Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC38A1 SLC34A1 TRPM2 SCN8A SLC6A5 SCN10A SLC34A2 SLC10A3 SLC1A1 SLC1A3

1.00e-111714910GO:0015081
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.60e-105494GO:0052871
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC38A1 SLC34A1 TRPM2 SCN8A SLC6A5 SCN10A SLC34A2 SLC10A3 KCNG3 SLC1A1 SLC1A3 ATP2B4

9.33e-104654912GO:0046873
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC38A1 SLC34A1 SLC6A5 SLC34A2 SLC10A3 SLC1A1 SLC1A3

1.04e-0981497GO:0015370
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.11e-097494GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.11e-097494GO:0018685
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC38A1 SLC34A1 TRPM2 SCN8A SLC6A5 SCN10A TMEM63B SLC34A2 SLC10A3 KCNG3 SLC1A1 SLC1A3 ATP2B4

2.37e-096274913GO:0022890
GeneOntologyMolecularFunctionsymporter activity

SLC38A1 SLC34A1 SLC6A5 MFSD2B SLC34A2 SLC10A3 SLC1A1 SLC1A3

2.92e-09150498GO:0015293
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC38A1 SLC34A1 TRPM2 SCN8A SLC6A5 SCN10A TMEM63B SLC34A2 SLC10A3 KCNG3 SLC1A1 SLC1A3 ATP2B4

4.72e-096644913GO:0008324
GeneOntologyMolecularFunctiontransporter activity

SLC38A1 IGF1R SLC34A1 SLCO2B1 TRPM2 SCN8A SLC6A5 SCN10A TMEM63B MFSD2B SLC34A2 SLC10A3 KCNG3 SLC1A1 SLC1A3 ATP2B4 ABCG5

4.76e-0912894917GO:0005215
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.65e-0910494GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.65e-0910494GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.65e-0910494GO:0102033
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC38A1 SLC34A1 SLCO2B1 TRPM2 SCN8A SLC6A5 SCN10A TMEM63B MFSD2B SLC34A2 SLC10A3 KCNG3 SLC1A1 SLC1A3 ATP2B4 ABCG5

1.05e-0811804916GO:0022857
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC38A1 SLC34A1 SLC6A5 SLC34A2 SLC10A3 SLC1A1 SLC1A3

1.56e-08119497GO:0015294
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC38A1 SLC34A1 SLCO2B1 SLC6A5 MFSD2B SLC34A2 SLC10A3 SLC1A1 SLC1A3 ATP2B4 ABCG5

1.66e-084774911GO:0022804
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC38A1 SLC6A5 SLC10A3 SLC1A1 SLC1A3

2.22e-0835495GO:0005343
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.25e-0813494GO:0016713
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC38A1 SLC34A1 TRPM2 SCN8A SLC6A5 SCN10A TMEM63B SLC34A2 SLC10A3 KCNG3 SLC1A1 SLC1A3 ATP2B4

2.28e-087584913GO:0015318
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC38A1 SLC34A1 SLCO2B1 SLC6A5 MFSD2B SLC34A2 SLC10A3 SLC1A1 SLC1A3

3.74e-08296499GO:0015291
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC38A1 SLC34A1 TRPM2 SCN8A SLC6A5 SCN10A TMEM63B SLC34A2 SLC10A3 KCNG3 SLC1A1 SLC1A3 ATP2B4

3.87e-087934913GO:0015075
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

1.27e-0749495GO:0016712
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC38A1 SLC6A5 SLC1A1 SLC1A3

2.74e-0723494GO:0005283
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.28e-0724494GO:0008392
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.39e-0727494GO:0008391
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC38A1 SLC34A1 SLC6A5 SLC34A2 SLC10A3 SLC1A1 SLC1A3 ATP2B4

6.41e-07301498GO:0022853
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC38A1 SLC6A5 SLC1A1 SLC1A3

7.26e-0729494GO:0005416
GeneOntologyMolecularFunctionaromatase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.58e-0635494GO:0070330
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.74e-0640494GO:0016709
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC38A1 SLC6A5 SLC1A1 SLC1A3

3.03e-0641494GO:0015175
GeneOntologyMolecularFunction20-hydroxy-leukotriene B4 omega oxidase activity

CYP4F2 CYP4F3

5.90e-062492GO:0097258
GeneOntologyMolecularFunction20-aldehyde-leukotriene B4 20-monooxygenase activity

CYP4F2 CYP4F3

5.90e-062492GO:0097259
GeneOntologyMolecularFunctionarachidonate binding

CYP4F2 CYP4F12 CYP4F11

6.19e-0615493GO:0050544
GeneOntologyMolecularFunctionicosanoid binding

CYP4F2 CYP4F12 CYP4F11

7.60e-0616493GO:0050542
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4F2 CYP4F12 CYP4F11

7.60e-0616493GO:0050543
GeneOntologyMolecularFunctionmonooxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

9.04e-06115495GO:0004497
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC38A1 SLCO2B1 SLC6A5 SLC10A3 SLC1A1 SLC1A3

1.11e-05207496GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC38A1 SLCO2B1 SLC6A5 SLC10A3 SLC1A1 SLC1A3

1.14e-05208496GO:0005342
GeneOntologyMolecularFunctionglycine:sodium symporter activity

SLC38A1 SLC6A5

1.77e-053492GO:0015375
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC38A1 SLC6A5 SLC1A1 SLC1A3

2.76e-0571494GO:0015179
GeneOntologyMolecularFunctionheme binding

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

3.71e-05154495GO:0020037
GeneOntologyMolecularFunctionlong-chain fatty acid binding

CYP4F2 CYP4F12 CYP4F11

4.36e-0528493GO:0036041
GeneOntologyMolecularFunctiontetrapyrrole binding

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

5.01e-05164495GO:0046906
GeneOntologyMolecularFunctioniron ion binding

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

5.30e-05166495GO:0005506
GeneOntologyMolecularFunctionhigh-affinity L-glutamate transmembrane transporter activity

SLC1A1 SLC1A3

5.87e-055492GO:0005314
GeneOntologyMolecularFunctionglutamate:sodium symporter activity

SLC1A1 SLC1A3

5.87e-055492GO:0015501
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC38A1 SLCO2B1 SLC6A5 SLC10A3 SLC1A1 SLC1A3

7.80e-05293496GO:0008514
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

1.11e-04194495GO:0016705
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC38A1 SLC6A5 SLC1A1 SLC1A3

1.27e-04105494GO:0015171
GeneOntologyMolecularFunctionneutral L-amino acid:sodium symporter activity

SLC38A1 SLC6A5

1.64e-048492GO:0005295
GeneOntologyMolecularFunctionTAP complex binding

HLA-B HLA-H

2.10e-049492GO:0062061
GeneOntologyMolecularFunctionCD8 receptor binding

HLA-B HLA-H

2.10e-049492GO:0042610
GeneOntologyMolecularFunctionTAP1 binding

HLA-B HLA-H

2.62e-0410492GO:0046978
GeneOntologyMolecularFunctionTAP2 binding

HLA-B HLA-H

2.62e-0410492GO:0046979
GeneOntologyMolecularFunctionTAP binding

HLA-B HLA-H

2.62e-0410492GO:0046977
GeneOntologyMolecularFunctionglycine transmembrane transporter activity

SLC38A1 SLC6A5

2.62e-0410492GO:0015187
GeneOntologyMolecularFunctionsodium channel activity

TRPM2 SCN8A SCN10A

2.82e-0452493GO:0005272
GeneOntologyMolecularFunctioncarboxylic acid binding

CYP4F2 CYP4F12 SLC1A1 CYP4F11 SLC1A3

2.92e-04239495GO:0031406
GeneOntologyMolecularFunctionsodium:phosphate symporter activity

SLC34A1 SLC34A2

3.83e-0412492GO:0005436
GeneOntologyMolecularFunctionbeta-2-microglobulin binding

HLA-B HLA-H

3.83e-0412492GO:0030881
GeneOntologyMolecularFunctionorganic acid binding

CYP4F2 CYP4F12 SLC1A1 CYP4F11 SLC1A3

3.87e-04254495GO:0043177
GeneOntologyMolecularFunctionglutamate binding

SLC1A1 SLC1A3

5.27e-0414492GO:0016595
GeneOntologyMolecularFunctionsodium ion binding

SCN8A SLC34A2

5.27e-0414492GO:0031402
GeneOntologyMolecularFunctionL-glutamate transmembrane transporter activity

SLC1A1 SLC1A3

6.07e-0415492GO:0005313
GeneOntologyMolecularFunctionfatty acid binding

CYP4F2 CYP4F12 CYP4F11

6.49e-0469493GO:0005504
GeneOntologyMolecularFunctionnatural killer cell lectin-like receptor binding

HLA-B HLA-H

7.84e-0417492GO:0046703
GeneOntologyMolecularFunctionmonoatomic ion channel activity

TRPM2 SCN8A SCN10A TMEM63B KCNG3 SLC1A1

8.65e-04459496GO:0005216
GeneOntologyMolecularFunctionT cell receptor binding

HLA-B HLA-H

1.09e-0320492GO:0042608
GeneOntologyMolecularFunctionacidic amino acid transmembrane transporter activity

SLC1A1 SLC1A3

1.09e-0320492GO:0015172
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC38A1 SLC6A5 SLC1A1

1.11e-0383493GO:0015101
GeneOntologyMolecularFunctionlipid transporter activity

SLCO2B1 MFSD2B SLC10A3 ABCG5

1.35e-03196494GO:0005319
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TRPM2 SCN8A SCN10A TMEM63B KCNG3

1.49e-03343495GO:0005261
GeneOntologyMolecularFunctionphosphate transmembrane transporter activity

SLC34A1 SLC34A2

1.57e-0324492GO:0005315
GeneOntologyMolecularFunctionchannel activity

TRPM2 SCN8A SCN10A TMEM63B KCNG3 SLC1A1

1.72e-03525496GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

TRPM2 SCN8A SCN10A TMEM63B KCNG3 SLC1A1

1.74e-03526496GO:0022803
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN8A SCN10A

1.85e-0326492GO:0005248
GeneOntologyMolecularFunctionalkali metal ion binding

SCN8A SLC34A2

1.85e-0326492GO:0031420
GeneOntologyMolecularFunctionmonocarboxylic acid binding

CYP4F2 CYP4F12 CYP4F11

2.30e-03107493GO:0033293
GeneOntologyMolecularFunctionoxidoreductase activity

CYP4F2 CYP4F3 CYP4F12 ALDH1L1 CYP39A1 CYP4F11 ME3

2.51e-03766497GO:0016491
GeneOntologyMolecularFunctionMHC class I protein binding

HLA-B HLA-H

2.79e-0332492GO:0042288
GeneOntologyMolecularFunctionbile acid transmembrane transporter activity

SLCO2B1 SLC10A3

3.15e-0334492GO:0015125
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH-OH group of donors

CYP4F2 CYP4F3 ME3

4.72e-03138493GO:0016614
GeneOntologyMolecularFunction14-3-3 protein binding

HLA-B HLA-H

4.77e-0342492GO:0071889
GeneOntologyMolecularFunctionSH3 domain binding

ADAM19 SIRPB1 SOS1

5.21e-03143493GO:0017124
GeneOntologyMolecularFunctionprotein domain specific binding

ADAM19 SLC34A1 SLC34A2 SIRPB1 ITGB1 ATP2B4 SOS1

5.22e-03875497GO:0019904
GeneOntologyMolecularFunctionsodium channel regulator activity

FGF14 ATP2B4

5.23e-0344492GO:0017080
GeneOntologyMolecularFunctionpeptide antigen binding

HLA-B HLA-H

6.45e-0349492GO:0042605
GeneOntologyBiologicalProcessleukotriene B4 catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.20e-106494GO:0036101
GeneOntologyBiologicalProcessleukotriene B4 metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

9.78e-107494GO:0036102
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC38A1 SLC34A1 TRPM2 SCN8A SLC6A5 SCN10A SLC34A2 FGF14 ATP2B4

1.31e-09208499GO:0035725
GeneOntologyBiologicalProcessleukotriene catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.95e-098494GO:0036100
GeneOntologyBiologicalProcessicosanoid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

9.16e-0911494GO:1901523
GeneOntologyBiologicalProcessmenaquinone catabolic process

CYP4F2 CYP4F12 CYP4F11

1.26e-083493GO:0042361
GeneOntologyBiologicalProcesslong-chain fatty acid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.37e-0812494GO:0042758
GeneOntologyBiologicalProcesssodium ion transport

SLC38A1 SLC34A1 TRPM2 SCN8A SLC6A5 SCN10A SLC34A2 FGF14 ATP2B4

1.51e-08275499GO:0006814
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC38A1 SLC34A1 TRPM2 SCN8A SLC6A5 SCN10A TMEM63B SLC34A2 FGF14 KCNG3 ITGB1 SLC1A1 SLC1A3 ATP2B4

2.36e-089424914GO:0098655
GeneOntologyBiologicalProcessmenaquinone metabolic process

CYP4F2 CYP4F12 CYP4F11

5.03e-084493GO:0009233
GeneOntologyBiologicalProcessphylloquinone metabolic process

CYP4F2 CYP4F12 CYP4F11

5.03e-084493GO:0042374
GeneOntologyBiologicalProcessphylloquinone catabolic process

CYP4F2 CYP4F12 CYP4F11

5.03e-084493GO:0042376
GeneOntologyBiologicalProcessvitamin K catabolic process

CYP4F2 CYP4F12 CYP4F11

5.03e-084493GO:0042377
GeneOntologyBiologicalProcessimport across plasma membrane

SLC38A1 SLC34A1 TRPM2 SLC6A5 ITGB1 SLC1A1 SLC1A3 ATP2B4

6.44e-08230498GO:0098739
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC38A1 SLC34A1 TRPM2 SCN8A SLC6A5 SCN10A SLC34A2 FGF14 KCNG3 ITGB1 SLC1A1 SLC1A3 ATP2B4

1.54e-079224913GO:0098662
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC38A1 SLC34A1 TRPM2 SCN8A SLC6A5 SCN10A TMEM63B SLC34A2 FGF14 KCNG3 ITGB1 SLC1A1 SLC1A3 ATP2B4

1.91e-0711154914GO:0034220
GeneOntologyBiologicalProcessfatty acid derivative catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.99e-0722494GO:1901569
GeneOntologyBiologicalProcessprostaglandin catabolic process

CYP4F2 CYP4F12 CYP4F11

2.51e-076493GO:1905344
GeneOntologyBiologicalProcessprostanoid catabolic process

CYP4F2 CYP4F12 CYP4F11

2.51e-076493GO:0062232
GeneOntologyBiologicalProcessamino acid import across plasma membrane

SLC38A1 SLC6A5 ITGB1 SLC1A1 SLC1A3

2.56e-0758495GO:0089718
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC38A1 SLC34A1 TRPM2 SCN8A SLC6A5 SCN10A TMEM63B SLC34A2 FGF14 KCNG3 ITGB1 SLC1A1 SLC1A3 ATP2B4

3.00e-0711574914GO:0006812
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC38A1 SLC34A1 SLCO2B1 TRPM2 SCN8A SLC6A5 SCN10A TMEM63B SLC34A2 FGF14 KCNG3 ITGB1 SLC1A1 SLC1A3 ATP2B4

3.81e-0713744915GO:0006811
GeneOntologyBiologicalProcessmetal ion transport

SLC38A1 SLC34A1 TRPM2 SCN8A SLC6A5 SCN10A SLC34A2 FGF14 KCNG3 ITGB1 SLC1A1 SLC1A3 ATP2B4

3.90e-0710004913GO:0030001
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC38A1 SLC34A1 TRPM2 SCN8A SLC6A5 SCN10A SLC34A2 FGF14 KCNG3 ITGB1 SLC1A1 SLC1A3 ATP2B4

4.73e-0710174913GO:0098660
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

8.16e-0773495GO:1901616
GeneOntologyBiologicalProcessL-alpha-amino acid transmembrane transport

SLC38A1 SLC6A5 ITGB1 SLC1A1 SLC1A3

1.96e-0687495GO:1902475
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLC38A1 SLCO2B1 SLC1A1 SLC1A3 ATP2B4

1.96e-0687495GO:0150104
GeneOntologyBiologicalProcessvitamin K metabolic process

CYP4F2 CYP4F12 CYP4F11

2.05e-0611493GO:0042373
GeneOntologyBiologicalProcessvascular transport

SLC38A1 SLCO2B1 SLC1A1 SLC1A3 ATP2B4

2.07e-0688495GO:0010232
GeneOntologyBiologicalProcessleukotriene metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.67e-0641494GO:0006691
GeneOntologyBiologicalProcessfat-soluble vitamin catabolic process

CYP4F2 CYP4F12 CYP4F11

2.73e-0612493GO:0042363
GeneOntologyBiologicalProcessorganic acid catabolic process

CYP4F2 CYP4F3 CYP4F12 ALDH1L1 CYP39A1 CYP4F11 ATP2B4

3.44e-06272497GO:0016054
GeneOntologyBiologicalProcesscarboxylic acid catabolic process

CYP4F2 CYP4F3 CYP4F12 ALDH1L1 CYP39A1 CYP4F11 ATP2B4

3.44e-06272497GO:0046395
GeneOntologyBiologicalProcessomega-hydroxylase P450 pathway

CYP4F2 CYP4F12 CYP4F11

4.50e-0614493GO:0097267
GeneOntologyBiologicalProcesscarboxylic acid transport

SLC38A1 SLCO2B1 SLC6A5 CYP4F2 SLC10A3 ITGB1 SLC1A1 SLC1A3

5.03e-06410498GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

SLC38A1 SLCO2B1 SLC6A5 CYP4F2 SLC10A3 ITGB1 SLC1A1 SLC1A3

5.21e-06412498GO:0015849
GeneOntologyBiologicalProcessL-amino acid transport

SLC38A1 SLC6A5 ITGB1 SLC1A1 SLC1A3

5.69e-06108495GO:0015807
GeneOntologyBiologicalProcessneurotransmitter uptake

SLC38A1 SLC6A5 ITGB1 SLC1A3

7.00e-0652494GO:0001504
GeneOntologyBiologicalProcesscirculatory system process

SLC38A1 SLCO2B1 SCN8A SCN10A CYP4F2 CYP4F12 ITGB1 SLC1A1 SLC1A3 ATP2B4

7.07e-067334910GO:0003013
GeneOntologyBiologicalProcessnon-proteinogenic amino acid biosynthetic process

SLC38A1 SLC1A3 ATP2B4

8.37e-0617493GO:0170043
GeneOntologyBiologicalProcessamino acid transmembrane transport

SLC38A1 SLC6A5 ITGB1 SLC1A1 SLC1A3

9.53e-06120495GO:0003333
GeneOntologyBiologicalProcessvitamin catabolic process

CYP4F2 CYP4F12 CYP4F11

1.00e-0518493GO:0009111
GeneOntologyBiologicalProcessL-glutamate import across plasma membrane

ITGB1 SLC1A1 SLC1A3

1.19e-0519493GO:0098712
GeneOntologyBiologicalProcessneutral amino acid transport

SLC38A1 SLC6A5 SLC1A1 SLC1A3

1.24e-0560494GO:0015804
GeneOntologyBiologicalProcessketone catabolic process

CYP4F2 CYP4F12 CYP4F11

1.63e-0521493GO:0042182
GeneOntologyBiologicalProcessarachidonate metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.05e-0568494GO:0019369
GeneOntologyBiologicalProcessmonocarboxylic acid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

2.38e-05145495GO:0072329
GeneOntologyBiologicalProcesscarboxylic acid metabolic process

SLC38A1 SLC34A1 CYP4F2 CYP4F3 CYP4F12 ALDH1L1 CYP39A1 CYP4F11 SLC1A3 ATP2B4 ME3

2.42e-0510354911GO:0019752
GeneOntologyBiologicalProcessorganic anion transport

SLC38A1 SLCO2B1 SLC6A5 CYP4F2 SLC10A3 ITGB1 SLC1A1 SLC1A3

2.62e-05515498GO:0015711
GeneOntologyBiologicalProcessoxoacid metabolic process

SLC38A1 SLC34A1 CYP4F2 CYP4F3 CYP4F12 ALDH1L1 CYP39A1 CYP4F11 SLC1A3 ATP2B4 ME3

2.96e-0510584911GO:0043436
GeneOntologyBiologicalProcessorganic acid metabolic process

SLC38A1 SLC34A1 CYP4F2 CYP4F3 CYP4F12 ALDH1L1 CYP39A1 CYP4F11 SLC1A3 ATP2B4 ME3

3.12e-0510644911GO:0006082
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC38A1 SLC6A5 ITGB1 SLC1A1 SLC1A3

4.17e-05163495GO:1905039
GeneOntologyBiologicalProcessfatty acid derivative metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.29e-0582494GO:1901568
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC38A1 SLC6A5 ITGB1 SLC1A1 SLC1A3

4.68e-05167495GO:1903825
GeneOntologyBiologicalProcesssmall molecule catabolic process

CYP4F2 CYP4F3 CYP4F12 ALDH1L1 CYP39A1 CYP4F11 ATP2B4

5.76e-05421497GO:0044282
GeneOntologyBiologicalProcessL-glutamate transmembrane transport

ITGB1 SLC1A1 SLC1A3

7.82e-0535493GO:0015813
GeneOntologyBiologicalProcessD-aspartate import across plasma membrane

SLC1A1 SLC1A3

8.24e-056492GO:0070779
GeneOntologyBiologicalProcessD-aspartate transmembrane transport

SLC1A1 SLC1A3

8.24e-056492GO:0070777
GeneOntologyBiologicalProcessvitamin E metabolic process

CYP4F2 CYP4F12

8.24e-056492GO:0042360
GeneOntologyBiologicalProcessgamma-aminobutyric acid biosynthetic process

SLC38A1 SLC1A3

8.24e-056492GO:0009449
GeneOntologyBiologicalProcessL-aspartate import across plasma membrane

SLC1A1 SLC1A3

8.24e-056492GO:0140009
GeneOntologyBiologicalProcessamino acid transport

SLC38A1 SLC6A5 ITGB1 SLC1A1 SLC1A3

9.76e-05195495GO:0006865
GeneOntologyBiologicalProcesscellular response to alkaloid

SLC34A1 SLC1A1 SLC1A3

1.17e-0440493GO:0071312
GeneOntologyBiologicalProcesshippocampus development

IGF1R PTPRS BBS1 ATP2B4

1.26e-04108494GO:0021766
GeneOntologyBiologicalProcesschemical homeostasis

IGF1R SLC34A1 TRPM2 TMEM63B SLC34A2 CYP4F12 CYP39A1 SLC1A1 SLC1A3 ATP2B4 ABCG5

1.33e-0412494911GO:0048878
GeneOntologyBiologicalProcessresponse to wounding

IGF1R PTPRS MFSD2B CYP4F2 ITGB1 SLC1A1 CYP4F11 SLC1A3

1.47e-04659498GO:0009611
GeneOntologyBiologicalProcessregulation of pro-B cell differentiation

SOS1 SOS2

1.53e-048492GO:2000973
GeneOntologyBiologicalProcessD-amino acid transport

SLC1A1 SLC1A3

1.53e-048492GO:0042940
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent

HLA-B HLA-H

1.53e-048492GO:0002485
GeneOntologyBiologicalProcessgamma-aminobutyric acid metabolic process

SLC38A1 SLC1A3

1.53e-048492GO:0009448
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

SLC38A1 IGF1R PTPRD PTPRS FGF14 ITGB1 SLC1A1 SLC1A3

1.54e-04663498GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

SLC38A1 IGF1R PTPRD PTPRS FGF14 ITGB1 SLC1A1 SLC1A3

1.55e-04664498GO:0099177
GeneOntologyBiologicalProcessvascular process in circulatory system

SLC38A1 SLCO2B1 ITGB1 SLC1A1 SLC1A3 ATP2B4

1.57e-04344496GO:0003018
GeneOntologyBiologicalProcessfatty acid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.66e-04116494GO:0009062
GeneOntologyBiologicalProcessL-glutamate import

ITGB1 SLC1A1 SLC1A3

1.78e-0446493GO:0051938
GeneOntologyBiologicalProcesslong-chain fatty acid metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.14e-04124494GO:0001676
GeneOntologyBiologicalProcessresponse to alkaloid

IGF1R SLC34A1 SLC1A1 SLC1A3

2.21e-04125494GO:0043279
GeneOntologyBiologicalProcessresponse to xenobiotic stimulus

SLC34A1 SLCO2B1 CYP4F2 CYP4F12 SLC1A1 SLC1A3 ABCG5

2.26e-04525497GO:0009410
GeneOntologyBiologicalProcessunsaturated fatty acid metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.42e-04128494GO:0033559
GeneOntologyBiologicalProcessfat-soluble vitamin metabolic process

CYP4F2 CYP4F12 CYP4F11

2.42e-0451493GO:0006775
GeneOntologyBiologicalProcesscellular response to cocaine

SLC1A1 SLC1A3

2.46e-0410492GO:0071314
GeneOntologyBiologicalProcessvitamin metabolic process

CYP4F2 CYP4F12 ALDH1L1 CYP4F11

2.80e-04133494GO:0006766
GeneOntologyBiologicalProcessmonocarboxylic acid metabolic process

SLC38A1 CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11 SLC1A3 ME3

2.98e-04731498GO:0032787
GeneOntologyBiologicalProcessL-aspartate transmembrane transport

SLC1A1 SLC1A3

3.00e-0411492GO:0070778
GeneOntologyBiologicalProcessintracellular phosphate ion homeostasis

SLC34A1 SLC34A2

3.00e-0411492GO:0030643
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

SLC38A1 IGF1R PTPRD PTPRS SLC6A5 FGF14 ITGB1 SLC1A1 SLC1A3

3.02e-04931499GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

SLC38A1 IGF1R PTPRD PTPRS SLC6A5 FGF14 ITGB1 SLC1A1 SLC1A3

3.02e-04931499GO:0007268
GeneOntologyBiologicalProcesstrans-synaptic signaling

SLC38A1 IGF1R PTPRD PTPRS SLC6A5 FGF14 ITGB1 SLC1A1 SLC1A3

3.21e-04939499GO:0099537
GeneOntologyBiologicalProcesslimbic system development

IGF1R PTPRS BBS1 ATP2B4

3.49e-04141494GO:0021761
GeneOntologyBiologicalProcesspostsynaptic density organization

PTPRD PTPRS ITGB1

3.55e-0458493GO:0097106
GeneOntologyBiologicalProcessicosanoid metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.59e-04142494GO:0006690
GeneOntologyBiologicalProcessregulation of lymphoid progenitor cell differentiation

SOS1 SOS2

3.59e-0412492GO:1905456
GeneOntologyBiologicalProcesscellular response to nitrogen compound

IGF1R SLC34A1 TRPM2 SLC1A1 SLC1A3 ATP2B4 SOS1 SOS2

3.61e-04752498GO:1901699
GeneOntologyBiologicalProcessneurotransmitter transport

SLC38A1 SLC6A5 ITGB1 SLC1A1 SLC1A3

3.65e-04259495GO:0006836
GeneOntologyBiologicalProcesspro-B cell differentiation

SOS1 SOS2

4.24e-0413492GO:0002328
GeneOntologyBiologicalProcesssodium-dependent phosphate transport

SLC34A1 SLC34A2

4.24e-0413492GO:0044341
GeneOntologyBiologicalProcesssynaptic signaling

SLC38A1 IGF1R PTPRD PTPRS SLC6A5 FGF14 ITGB1 SLC1A1 SLC1A3

4.27e-04976499GO:0099536
GeneOntologyBiologicalProcesspositive regulation of organic acid transport

SLC38A1 CYP4F2 ITGB1

4.53e-0463493GO:0032892
GeneOntologyBiologicalProcessresponse to mercury ion

SLC34A1 SLC1A1

4.94e-0414492GO:0046689
GeneOntologyBiologicalProcessglycine transport

SLC38A1 SLC6A5

5.69e-0415492GO:0015816
GeneOntologyCellularComponentapical plasma membrane

SLC38A1 SLC34A1 SLCO2B1 SLC34A2 CYP4F2 CYP4F3 CYP4F12 SLC1A1 CYP4F11 ABCG5

1.56e-074874910GO:0016324
GeneOntologyCellularComponentapical part of cell

SLC38A1 SLC34A1 SLCO2B1 SLC34A2 CYP4F2 CYP4F3 CYP4F12 SLC1A1 CYP4F11 ABCG5

9.34e-075924910GO:0045177
GeneOntologyCellularComponentsecretory granule membrane

HLA-B TRPM2 HLA-H TMEM63B LAMP3 CD46 SIRPB1

1.09e-05329497GO:0030667
GeneOntologyCellularComponentalveolar lamellar body membrane

TMEM63B LAMP3

1.61e-053492GO:0097233
GeneOntologyCellularComponentlamellar body membrane

TMEM63B LAMP3

3.22e-054492GO:0097232
GeneOntologyCellularComponentcell surface

SLC38A1 ADAM19 HLA-B SLC34A1 HLA-H LAMP3 CD46 SIRPB1 ITGB1 SLC1A1 SLC1A3

4.10e-0511114911GO:0009986
GeneOntologyCellularComponentpresynaptic membrane

PTPRD PTPRS SCN8A SLC6A5 SCN10A ATP2B4

4.45e-05277496GO:0042734
GeneOntologyCellularComponentbasolateral plasma membrane

SLC38A1 SLC34A1 SLCO2B1 CD46 SLC1A3 ATP2B4

9.87e-05320496GO:0016323
GeneOntologyCellularComponentsecretory granule

HLA-B TRPM2 SLC6A5 HLA-H TMEM63B LAMP3 CD46 SIRPB1 ITGB1 IQUB

1.01e-0410144910GO:0030141
GeneOntologyCellularComponentMHC class Ib protein complex

HLA-B HLA-H

1.12e-047492GO:0032398
GeneOntologyCellularComponentsecretory vesicle

HLA-B PTPRS TRPM2 SLC6A5 HLA-H TMEM63B LAMP3 CD46 SIRPB1 ITGB1 IQUB

1.15e-0412464911GO:0099503
GeneOntologyCellularComponentearly endosome membrane

HLA-B HLA-H TMEM63B LAMP3 SLC1A1

1.36e-04212495GO:0031901
GeneOntologyCellularComponentbasal plasma membrane

SLC38A1 SLC34A1 SLCO2B1 CD46 SLC1A3 ATP2B4

1.71e-04354496GO:0009925
GeneOntologyCellularComponentmembrane raft

IGF1R HLA-B HLA-H ITGB1 SLC1A1 ATP2B4

1.93e-04362496GO:0045121
GeneOntologyCellularComponentmembrane microdomain

IGF1R HLA-B HLA-H ITGB1 SLC1A1 ATP2B4

1.99e-04364496GO:0098857
GeneOntologyCellularComponentMHC class I protein complex

HLA-B HLA-H

2.39e-0410492GO:0042612
GeneOntologyCellularComponentalveolar lamellar body

TMEM63B LAMP3

2.39e-0410492GO:0097208
GeneOntologyCellularComponentbasal part of cell

SLC38A1 SLC34A1 SLCO2B1 CD46 SLC1A3 ATP2B4

2.44e-04378496GO:0045178
GeneOntologyCellularComponentcell body

SLC38A1 IGF1R PTPRS TMEM132E TRPM2 SCN8A SLC1A1 SLC1A3 SOS1

2.69e-04929499GO:0044297
GeneOntologyCellularComponentsynaptic membrane

PTPRD PTPRS SCN8A SLC6A5 SCN10A ITGB1 ATP2B4

3.93e-04583497GO:0097060
GeneOntologyCellularComponentplasma membrane protein complex

IGF1R HLA-B SCN8A HLA-H SCN10A KCNG3 ITGB1 ABCG5

4.39e-04785498GO:0098797
GeneOntologyCellularComponentSchaffer collateral - CA1 synapse

PTPRD PTPRS ITGB1 SLC1A1

4.75e-04155494GO:0098685
GeneOntologyCellularComponentMHC class I peptide loading complex

HLA-B HLA-H

4.81e-0414492GO:0042824
GeneOntologyCellularComponentneuronal cell body

SLC38A1 IGF1R PTPRS TRPM2 SCN8A SLC1A1 SLC1A3 SOS1

6.61e-04835498GO:0043025
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN8A SCN10A

7.16e-0417492GO:0001518
GeneOntologyCellularComponentcis-Golgi network membrane

HLA-B HLA-H

7.16e-0417492GO:0033106
GeneOntologyCellularComponentcytoplasmic vesicle membrane

HLA-B PTPRS TRPM2 HLA-H TMEM63B LAMP3 CD46 SIRPB1 ITGB1 SLC1A1

7.71e-0413074910GO:0030659
GeneOntologyCellularComponentvesicle membrane

HLA-B PTPRS TRPM2 HLA-H TMEM63B LAMP3 CD46 SIRPB1 ITGB1 SLC1A1

8.57e-0413254910GO:0012506
GeneOntologyCellularComponentglycinergic synapse

SLC6A5 ITGB1

9.95e-0420492GO:0098690
GeneOntologyCellularComponentlamellar body

TMEM63B LAMP3

1.10e-0321492GO:0042599
GeneOntologyCellularComponentGolgi medial cisterna

HLA-B HLA-H

1.32e-0323492GO:0005797
GeneOntologyCellularComponentMHC protein complex

HLA-B HLA-H

1.69e-0326492GO:0042611
GeneOntologyCellularComponentrecycling endosome

HLA-B HLA-H ITGB1 SLC1A1

1.80e-03222494GO:0055037
GeneOntologyCellularComponentsomatodendritic compartment

SLC38A1 IGF1R PTPRS TRPM2 SCN8A ITGB1 SLC1A1 SLC1A3 SOS1

1.97e-031228499GO:0036477
GeneOntologyCellularComponentsodium channel complex

SCN8A SCN10A

2.10e-0329492GO:0034706
GeneOntologyCellularComponentrecycling endosome membrane

HLA-B HLA-H SLC1A1

2.31e-03112493GO:0055038
GeneOntologyCellularComponentendosome membrane

HLA-B HLA-H TMEM63B LAMP3 ITGB1 SLC1A1

2.72e-03602496GO:0010008
GeneOntologyCellularComponentglutamatergic synapse

IGF1R PTPRD PTPRS SCN8A SCN10A ITGB1 ATP2B4

2.79e-03817497GO:0098978
GeneOntologyCellularComponentendoplasmic reticulum membrane

HLA-B LPCAT4 HLA-H CYP4F2 CYP4F3 CYP4F12 IFI27 CYP39A1 CYP4F11

2.80e-031293499GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

HLA-B LPCAT4 HLA-H CYP4F2 CYP4F3 CYP4F12 IFI27 CYP39A1 CYP4F11

2.89e-031299499GO:0098827
GeneOntologyCellularComponentlumenal side of endoplasmic reticulum membrane

HLA-B HLA-H

3.05e-0335492GO:0098553
GeneOntologyCellularComponentendoplasmic reticulum protein-containing complex

GANAB HLA-B HLA-H

3.15e-03125493GO:0140534
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

HLA-B LPCAT4 HLA-H CYP4F2 CYP4F3 CYP4F12 IFI27 CYP39A1 CYP4F11

3.34e-031327499GO:0042175
GeneOntologyCellularComponentpresynapse

PTPRD PTPRS SCN8A SLC6A5 SCN10A SLC1A1 ATP2B4

4.36e-03886497GO:0098793
GeneOntologyCellularComponentendoplasmic reticulum exit site

HLA-B HLA-H

4.37e-0342492GO:0070971
GeneOntologyCellularComponentearly endosome

HLA-B HLA-H TMEM63B LAMP3 SLC1A1

5.24e-03481495GO:0005769
GeneOntologyCellularComponentendosome

HLA-B SLC34A1 SLC6A5 HLA-H TMEM63B LAMP3 ITGB1 SLC1A1

5.39e-031167498GO:0005768
GeneOntologyCellularComponentglial cell projection

ITGB1 SLC1A1

5.44e-0347492GO:0097386
GeneOntologyCellularComponentlumenal side of membrane

HLA-B HLA-H

5.67e-0348492GO:0098576
GeneOntologyCellularComponentexternal side of plasma membrane

SLC38A1 ADAM19 HLA-B HLA-H ITGB1

7.18e-03519495GO:0009897
GeneOntologyCellularComponentmembrane protein complex

IGF1R HLA-B SCN8A HLA-H SCN10A KCNG3 ITGB1 SLC1A3 ABCG5

7.35e-031498499GO:0098796
GeneOntologyCellularComponentneuron to neuron synapse

PTPRD PTPRS SCN8A ITGB1 SLC1A1

7.41e-03523495GO:0098984
GeneOntologyCellularComponentER to Golgi transport vesicle membrane

HLA-B HLA-H

9.89e-0364492GO:0012507
GeneOntologyCellularComponentsarcolemma

IGF1R ITGB1 ATP2B4

1.00e-02190493GO:0042383
GeneOntologyCellularComponentacrosomal vesicle

CD46 ITGB1 IQUB

1.25e-02206493GO:0001669
GeneOntologyCellularComponentaxoneme

CFAP54 BBS1 IQUB

1.26e-02207493GO:0005930
GeneOntologyCellularComponentciliary plasm

CFAP54 BBS1 IQUB

1.28e-02208493GO:0097014
GeneOntologyCellularComponentpresynaptic active zone membrane

SCN8A ATP2B4

1.44e-0278492GO:0048787
GeneOntologyCellularComponentT-tubule

IGF1R ATP2B4

1.48e-0279492GO:0030315
GeneOntologyCellularComponentperikaryon

PTPRS TRPM2 SLC1A1

1.54e-02223493GO:0043204
GeneOntologyCellularComponentbrush border membrane

SLC34A1 SLC34A2

1.62e-0283492GO:0031526
GeneOntologyCellularComponentphagocytic vesicle membrane

HLA-B HLA-H

1.62e-0283492GO:0030670
DomainCYTOCHROME_P450

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

3.81e-0757495PS00086
Domain-

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

4.16e-07584951.10.630.10
Domainp450

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

4.16e-0758495PF00067
DomainCyt_P450

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

4.94e-0760495IPR001128
DomainCyt_P450_E_grp-I

CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.75e-0645494IPR002401
DomainCyt_P450_CS

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.11e-0553494IPR017972
DomainNa/Pi_transpt

SLC34A1 SLC34A2

2.02e-053492IPR003841
DomainNa_Pi_cotrans

SLC34A1 SLC34A2

2.02e-053492PF02690
DomainMHC_I_a_C

HLA-B HLA-H

1.00e-046492IPR010579
DomainMHC_I_C

HLA-B HLA-H

1.00e-046492PF06623
DomainFN3

LRIT2 IGF1R PTPRD PTPRS SPEG

1.21e-04185495SM00060
DomainNa-dicarboxylate_symporter

SLC1A1 SLC1A3

1.40e-047492IPR001991
DomainNA_DICARBOXYL_SYMP_1

SLC1A1 SLC1A3

1.40e-047492PS00713
DomainNA_DICARBOXYL_SYMP_2

SLC1A1 SLC1A3

1.40e-047492PS00714
DomainNa-dicarboxylate_symporter_CS

SLC1A1 SLC1A3

1.40e-047492IPR018107
DomainSDF

SLC1A1 SLC1A3

1.40e-047492PF00375
Domain-

SLC1A1 SLC1A3

1.40e-0474921.10.3860.10
DomainFN3

LRIT2 IGF1R PTPRD PTPRS SPEG

1.70e-04199495PS50853
DomainFN3_dom

LRIT2 IGF1R PTPRD PTPRS SPEG

2.14e-04209495IPR003961
DomainIon_trans_dom

TRPM2 SCN8A SCN10A KCNG3

2.26e-04114494IPR005821
DomainIon_trans

TRPM2 SCN8A SCN10A KCNG3

2.26e-04114494PF00520
DomainIG_LIKE

LRIT2 PTPRD HLA-B PTPRS SPEG HLA-H SIRPB1

2.75e-04491497PS50835
DomainNa_channel_asu

SCN8A SCN10A

2.99e-0410492IPR001696
DomainCyt_P450_E_grp-IV

CYP4F12 CYP39A1

2.99e-0410492IPR002403
DomainNa_trans_assoc

SCN8A SCN10A

2.99e-0410492IPR010526
DomainNa_trans_assoc

SCN8A SCN10A

2.99e-0410492PF06512
DomainIg-like_dom

LRIT2 PTPRD HLA-B PTPRS SPEG HLA-H SIRPB1

3.18e-04503497IPR007110
DomainC1-set

HLA-B HLA-H SIRPB1

3.83e-0454493PF07654
DomainIGc1

HLA-B HLA-H SIRPB1

4.27e-0456493SM00407
DomainChannel_four-helix_dom

SCN8A SCN10A KCNG3

4.49e-0457493IPR027359
Domain-

SCN8A SCN10A KCNG3

4.49e-04574931.20.120.350
DomainIg-like_fold

LRIT2 IGF1R PTPRD HLA-B PTPRS SPEG HLA-H SIRPB1

4.58e-04706498IPR013783
DomainIg_C1-set

HLA-B HLA-H SIRPB1

4.73e-0458493IPR003597
DomainRas_G-nucl-exch_fac_CS

SOS1 SOS2

6.01e-0414492IPR019804
Domainfn3

IGF1R PTPRD PTPRS SPEG

8.53e-04162494PF00041
DomainRasGEFN

SOS1 SOS2

1.24e-0320492SM00229
DomainRasGEF_N

SOS1 SOS2

1.37e-0321492PF00618
DomainMHC_I

HLA-B HLA-H

1.37e-0321492PF00129
DomainMHC_I_a_a1/a2

HLA-B HLA-H

1.37e-0321492IPR001039
DomainRas-like_Gua-exchang_fac_N

SOS1 SOS2

1.51e-0322492IPR000651
DomainRASGEF_NTER

SOS1 SOS2

1.51e-0322492PS50212
DomainIg_I-set

LRIT2 PTPRD PTPRS SPEG

1.54e-03190494IPR013098
DomainI-set

LRIT2 PTPRD PTPRS SPEG

1.54e-03190494PF07679
Domain-

LRIT2 IGF1R PTPRD HLA-B PTPRS SPEG SIRPB1

1.62e-036634972.60.40.10
DomainIQ

SCN8A SCN10A IQUB

1.87e-0393493PS50096
DomainRASGEF

SOS1 SOS2

2.11e-0326492PS00720
DomainRASGEF_CAT

SOS1 SOS2

2.62e-0329492PS50009
DomainRasGEF

SOS1 SOS2

2.80e-0330492PF00617
Domain-

SOS1 SOS2

2.80e-03304921.10.840.10
DomainRas_GEF_dom

SOS1 SOS2

2.80e-0330492IPR023578
DomainRASGEF_cat_dom

SOS1 SOS2

2.80e-0330492IPR001895
DomainRasGEF

SOS1 SOS2

2.80e-0330492SM00147
DomainIGc2

LRIT2 PTPRD PTPRS SPEG

3.32e-03235494SM00408
DomainIg_sub2

LRIT2 PTPRD PTPRS SPEG

3.32e-03235494IPR003598
DomainPTPc

PTPRD PTPRS

4.01e-0336492SM00194
DomainGDS_CDC24_CS

SOS1 SOS2

4.70e-0339492IPR001331
DomainTYR_PHOSPHATASE_PTP

PTPRD PTPRS

4.70e-0339492PS50055
DomainIG

LRIT2 PTPRD PTPRS SPEG SIRPB1

4.80e-03421495SM00409
DomainIg_sub

LRIT2 PTPRD PTPRS SPEG SIRPB1

4.80e-03421495IPR003599
DomainPTPase_domain

PTPRD PTPRS

5.18e-0341492IPR000242
DomainY_phosphatase

PTPRD PTPRS

5.18e-0341492PF00102
PathwayREACTOME_EICOSANOIDS

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.65e-0812434M27129
PathwayREACTOME_EICOSANOIDS

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.65e-0812434MM14845
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES

CYP4F2 CYP4F3 CYP4F12 CYP4F11

7.35e-0814434MM15842
PathwayREACTOME_FATTY_ACIDS

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.00e-0715434M27126
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.23e-0718434MM14843
PathwayREACTOME_FATTY_ACIDS

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.23e-0718434MM14841
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F2 CYP4F3 CYP4F12 CYP4F11

9.06e-0725434MM14858
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

1.18e-0662435M39653
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

1.39e-0664435M5650
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

1.62e-0666435MM14839
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.88e-0633434MM15918
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.88e-0633434MM15963
PathwayREACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE

CYP4F2 CYP4F12 CYP4F11

4.29e-0611433MM14863
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4F3 CYP4F11

5.71e-0612433M27128
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC38A1 SLC34A1 SLCO2B1 SLC6A5 SLC34A2 SLC1A1 SLC1A3

6.87e-06238437MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC38A1 SLC34A1 SLCO2B1 SLC6A5 SLC34A2 SLC1A1 SLC1A3

9.23e-06249437M5988
PathwayKEGG_MEDICUS_VARIANT_IGF2_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY

IGF1R SOS1 SOS2

1.17e-0515433M47485
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

SLC34A1 SLC6A5 SLC34A2 SLC1A1 SLC1A3

1.20e-0599435M27474
PathwayKEGG_MEDICUS_REFERENCE_IGF_IGF1R_RAS_ERK_SIGNALING_PATHWAY

IGF1R SOS1 SOS2

1.44e-0516433M47483
PathwayREACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS

SLC34A1 SLC6A5 SLC34A2 SLC1A1 SLC1A3 ABCG5

1.49e-05177436M27476
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

1.53e-05104435M738
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

1.60e-05105435MM14842
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC38A1 SLC34A1 SLC34A2 SLC1A1 SLC1A3

1.84e-05108435M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC38A1 SLC34A1 SLC34A2 SLC1A1 SLC1A3

1.92e-05109435MM15074
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC38A1 SLC34A1 SLCO2B1 TRPM2 SLC6A5 SLC34A2 SLC1A1 SLC1A3 ATP2B4 ABCG5

2.91e-056814310MM14985
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F2 CYP4F3 CYP4F11

3.38e-0521433M27137
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.45e-0561434MM14861
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC38A1 SLC34A1 SLCO2B1 TRPM2 SLC6A5 SLC34A2 SLC1A1 SLC1A3 ATP2B4 ABCG5

5.64e-057364310M27287
PathwayBIOCARTA_NKCELLS_PATHWAY

HLA-B HLA-H ITGB1

5.80e-0525433MM1465
PathwayBIOCARTA_ERK_PATHWAY

IGF1R ITGB1 SOS1

7.35e-0527433M287
PathwayBIOCARTA_ERK_PATHWAY

IGF1R ITGB1 SOS1

8.21e-0528433MM1391
PathwayREACTOME_SODIUM_COUPLED_PHOSPHATE_COTRANSPORTERS

SLC34A1 SLC34A2

9.04e-055432M27345
PathwayREACTOME_SODIUM_COUPLED_PHOSPHATE_COTRANSPORTERS

SLC34A1 SLC34A2

9.04e-055432MM15085
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN8A SCN10A FGF14

1.23e-0432433M27455
PathwayREACTOME_SHC_RELATED_EVENTS_TRIGGERED_BY_IGF1R

IGF1R SOS1

1.35e-046432MM14887
PathwayWP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

2.25e-04183435M39588
PathwayREACTOME_SHC_RELATED_EVENTS_TRIGGERED_BY_IGF1R

IGF1R SOS1

3.23e-049432M27173
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES_PATHWAY

CYP4F2 CYP4F12

3.23e-049432M39819
PathwayREACTOME_ENDOSOMAL_VACUOLAR_PATHWAY

HLA-B HLA-H

3.23e-049432MM14527
PathwayREACTOME_DAP12_INTERACTIONS

HLA-B SIRPB1 SOS1

3.66e-0446433M27151
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PATHWAY_ADAPTOR_PROTEINS

SOS1 SOS2

4.03e-0410432M47930
PathwayWP_TRYPTOPHAN_METABOLISM

CYP4F2 CYP4F12 CYP4F11

4.16e-0448433MM15902
PathwayREACTOME_INTERLEUKIN_15_SIGNALING

SOS1 SOS2

4.91e-0411432MM15578
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_RALGDS_SIGNALING_PATHWAY

SOS1 SOS2

4.91e-0411432M47436
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_RASSF1_SIGNALING_PATHWAY

SOS1 SOS2

4.91e-0411432M47432
PathwayREACTOME_NEURONAL_SYSTEM

SLC38A1 PTPRD PTPRS KCNG3 SLC1A1 SLC1A3

5.00e-04335436MM14503
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

5.15e-04219435MM14838
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

5.25e-04220435M10320
PathwayREACTOME_DAP12_INTERACTIONS

HLA-B HLA-H SOS1

5.88e-0454433MM14871
PathwayREACTOME_CARDIAC_CONDUCTION

SCN8A SCN10A FGF14 ATP2B4

6.45e-04130434M27454
PathwayWP_CELL_LINEAGE_MAP_FOR_NEURONAL_DIFFERENTIATION

SLC6A5 ALDH1L1 ITGB1 SLC1A3

6.83e-04132434M48110
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_JNK_SIGNALING_PATHWAY

SOS1 SOS2

6.94e-0413432M47594
PathwayREACTOME_ACTIVATION_OF_RAC1

SOS1 SOS2

6.94e-0413432M6322
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F2 CYP4F3 CYP4F11

7.63e-0459433M27140
PathwayKEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

8.08e-0414432M47364
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

8.08e-0414432M47365
PathwayKEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

8.08e-0414432M47366
PathwayKEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_PI3K_SIGNALING_PATHWAY

SOS1 SOS2

8.08e-0414432M47390
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

8.08e-0414432M47378
PathwayREACTOME_INTERLEUKIN_15_SIGNALING

SOS1 SOS2

8.08e-0414432M27858
PathwayKEGG_MEDICUS_VARIANT_MET_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

8.08e-0414432M47488
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47367
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47389
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47375
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47380
PathwayKEGG_MEDICUS_REFERENCE_CA2_PYK2_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47592
PathwayKEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47593
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF17_TO_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47640
PathwayKEGG_MEDICUS_REFERENCE_HGF_MET_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47473
PathwayKEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47474
PathwayKEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_PI3K_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47475
PathwayKEGG_MEDICUS_REFERENCE_TGFA_EGFR_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47480
PathwayKEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47495
PathwayKEGG_MEDICUS_REFERENCE_EREG_EGFR_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47496
PathwayKEGG_MEDICUS_REFERENCE_AREG_EGFR_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47497
PathwayKEGG_MEDICUS_REFERENCE_KITLG_KIT_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47472
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_GB_TO_PDGFR_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47535
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E5_TO_EGFR_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

9.31e-0415432M47531
PathwayKEGG_GLIOMA

IGF1R SOS1 SOS2

1.01e-0365433M1835
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

1.06e-0316432M47363
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_FGFR3_TO_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

1.06e-0316432M47373
PathwayKEGG_MEDICUS_REFERENCE_EGF_ERBB2_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

1.06e-0316432M47381
PathwayKEGG_MEDICUS_REFERENCE_P4_PR_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

1.06e-0316432M47804
PathwayWP_MAPK_PATHWAY_IN_CONGENITAL_THYROID_CANCER

SOS1 SOS2

1.06e-0316432M39882
PathwaySIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES

IFI27 SOS1 SOS2

1.11e-0367433M295
PathwayKEGG_MEDICUS_REFERENCE_PDGF_PDGFR_RAS_ERK_SIGNALING_PATHWAY

SOS1 SOS2

1.20e-0317432M47376
PathwayREACTOME_SIGNALING_BY_NTRK3_TRKC

PTPRS SOS1

1.20e-0317432M27918
PathwayBIOCARTA_PTEN_PATHWAY

ITGB1 SOS1

1.35e-0318432M10145
PathwayBIOCARTA_PTEN_PATHWAY

ITGB1 SOS1

1.35e-0318432MM1461
PathwayREACTOME_ER_PHAGOSOME_PATHWAY

HLA-B HLA-H

1.35e-0318432MM14525
PathwayREACTOME_NEURONAL_SYSTEM

SLC38A1 PTPRD PTPRS KCNG3 SLC1A1 SLC1A3

1.45e-03411436M735
PathwayBIOCARTA_CTL_PATHWAY

HLA-B HLA-H

1.67e-0320432MM1374
PathwayREACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES

PTPRD PTPRS

1.67e-0320432M27290
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

PTPRD PTPRS

1.67e-0320432MM15485
PathwayREACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES

PTPRD PTPRS

1.67e-0320432MM14991
PathwayREACTOME_INTERFERON_ALPHA_BETA_SIGNALING

HLA-B HLA-H IFI27

1.72e-0378433M973
PathwayREACTOME_FATTY_ACID_METABOLISM

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.75e-03170434MM15573
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

PTPRD PTPRS

1.84e-0321432M27736
PathwayBIOCARTA_IGF1_PATHWAY

IGF1R SOS1

1.84e-0321432M2623
PathwayBIOCARTA_IGF1_PATHWAY

IGF1R SOS1

2.02e-0322432MM1409
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.48e-12449418065749
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.20e-1164949068972
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

SLC38A1 SLCO2B1 ITGB1 SLC1A1 SLC1A3 ATP2B4

8.25e-0910549630280653
Pubmed

Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.

CYP4F2 CYP4F12 CYP4F11

1.05e-08449322665481
Pubmed

Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

CYP4F2 CYP4F12 CYP4F11

1.05e-08449311185557
Pubmed

Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.

CYP4F2 CYP4F12 CYP4F11

2.62e-08549322969154
Pubmed

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.

CYP4F2 CYP4F12 CYP4F11

2.62e-08549321466787
Pubmed

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

5.08e-087049515128046
Pubmed

Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice.

CYP4F2 CYP4F12 CYP4F11

9.16e-08749322160543
Pubmed

Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues.

CYP4F2 CYP4F12 CYP39A1 CYP4F11

4.53e-074449412745259
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

SLC38A1 SLCO2B1 SLC1A1 SLC1A3

8.95e-075249426590417
Pubmed

Selective modulation of type 1 insulin-like growth factor receptor signaling and functions by beta1 integrins.

IGF1R ITGB1

1.94e-06249215289498
Pubmed

Functional analysis of glutamate transporters in excitatory synaptic transmission of GLAST1 and GLAST1/EAAC1 deficient mice.

SLC1A1 SLC1A3

1.94e-06249215363892
Pubmed

Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11.

CYP4F2 CYP4F11

1.94e-06249224138531
Pubmed

Expression of CYP4F2 in human liver and kidney: assessment using targeted peptide antibodies.

CYP4F2 CYP4F12

1.94e-06249218662666
Pubmed

Expression and physiological function of CYP4F subfamily in human eosinophils.

CYP4F3 CYP4F12

1.94e-06249217980168
Pubmed

Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver.

CYP4F2 CYP4F3

1.94e-0624928026587
Pubmed

Integrin expression regulates neuroblastoma attachment and migration.

IGF1R ITGB1

1.94e-06249215256055
Pubmed

Protective effect of hyaluronic acid on interleukin-1-induced deregulation of beta1-integrin and insulin-like growth factor-I receptor signaling and collagen biosynthesis in cultured human chondrocytes.

IGF1R ITGB1

1.94e-06249217899316
Pubmed

FGF14 localization and organization of the axon initial segment.

SCN8A FGF14

1.94e-06249223891806
Pubmed

A homologue of the Drosophila Son of sevenless gene maps to mouse chromosome 17.

SOS1 SOS2

1.94e-0624928307589
Pubmed

Absence of both Sos-1 and Sos-2 in peripheral CD4(+) T cells leads to PI3K pathway activation and defects in migration.

SOS1 SOS2

1.94e-06249225973715
Pubmed

HLA-B influences integrin beta-1 expression and pancreatic cancer cell migration.

HLA-B ITGB1

1.94e-06249232194036
Pubmed

Identification of Amino Acid Residues in Fibroblast Growth Factor 14 (FGF14) Required for Structure-Function Interactions with Voltage-gated Sodium Channel Nav1.6.

SCN8A FGF14

1.94e-06249226994141
Pubmed

The fibroblast growth factor 14·voltage-gated sodium channel complex is a new target of glycogen synthase kinase 3 (GSK3).

SCN8A FGF14

1.94e-06249223640885
Pubmed

Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids.

CYP4F3 CYP4F11

1.94e-06249215364545
Pubmed

Mapping of the FGF14:Nav1.6 complex interface reveals FLPK as a functionally active peptide modulating excitability.

SCN8A FGF14

1.94e-06249232671946
Pubmed

Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras.

SOS1 SOS2

1.94e-0624921631150
Pubmed

The second catalytic domain of protein tyrosine phosphatase delta (PTP delta) binds to and inhibits the first catalytic domain of PTP sigma.

PTPRD PTPRS

1.94e-0624929566880
Pubmed

The role of an intracellular cysteine stretch in the sorting of the type II Na/phosphate cotransporter.

SLC34A1 SLC34A2

1.94e-06249217574207
Pubmed

SOS2 Comes to the Fore: Differential Functionalities in Physiology and Pathology.

SOS1 SOS2

1.94e-06249234205562
Pubmed

Neuron-specific human glutamate transporter: molecular cloning, characterization and expression in human brain.

SLC1A1 SLC1A3

1.94e-0624927859077
Pubmed

Type II Na+-Pi cotransporters in osteoblast mineral formation: regulation by inorganic phosphate.

SLC34A1 SLC34A2

1.94e-06249217310099
Pubmed

The Ras-specific exchange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1.

SOS1 SOS2

1.94e-0624929372945
Pubmed

Bioluminescence methodology for the detection of protein-protein interactions within the voltage-gated sodium channel macromolecular complex.

SCN8A FGF14

1.94e-06249222364545
Pubmed

Cloning and expression of a glutamate transporter from mouse brain.

SLC1A1 SLC1A3

1.94e-0624927903437
Pubmed

Critical Requirement of SOS1 for Development of BCR/ABL-Driven Chronic Myelogenous Leukemia.

SOS1 SOS2

1.94e-06249236010887
Pubmed

Functional Modulation of Voltage-Gated Sodium Channels by a FGF14-Based Peptidomimetic.

SCN8A FGF14

1.94e-06249229359916
Pubmed

Chromosomal localization of two genes encoding human ras exchange factors: SOS1 maps to the 2p22-->p16 region and SOS2 to the 14q21-->q22 region of the human genome.

SOS1 SOS2

1.94e-0624928275713
Pubmed

Expression of renal and intestinal Na/Pi cotransporters in the absence of GABARAP.

SLC34A1 SLC34A2

5.83e-06349220354864
Pubmed

The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma.

SLC1A1 SLC1A3

5.83e-06349217607354
Pubmed

Increased expression and function of glutamate transporters in multiple sclerosis.

SLC1A1 SLC1A3

5.83e-06349216061389
Pubmed

Growth-related renal type II Na/Pi cotransporter.

SLC34A1 SLC34A2

5.83e-06349211880379
Pubmed

High-affinity glutamate transporter GLAST/EAAT1 regulates cell surface expression of glutamine/neutral amino acid transporter ASCT2 in human fetal astrocytes.

SLC38A1 SLC1A3

5.83e-06349216516348
Pubmed

Insulin regulates neurovascular coupling through astrocytes.

IGF1R SLC1A3

5.83e-06349235858325
Pubmed

Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides.

CYP4F2 CYP4F3

5.83e-06349215145985
Pubmed

LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.

PTPRD PTPRS

5.83e-06349231985401
Pubmed

Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.

PTPRD PTPRS

5.83e-06349220139422
Pubmed

Trpm2 deficiency in microglia attenuates neuroinflammation during epileptogenesis by upregulating autophagy via the AMPK/mTOR pathway.

TRPM2 ALDH1L1

5.83e-06349237648036
Pubmed

Activation of β1 integrins and caveolin-1 by TF/FVIIa promotes IGF-1R signaling and cell survival.

IGF1R ITGB1

5.83e-06349232458278
Pubmed

Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.

PTPRD PTPRS

5.83e-0634929784606
Pubmed

A dominant-negative mutant of mSOS1 inhibits insulin-induced Ras activation and reveals Ras-dependent and -independent insulin signaling pathways.

IGF1R SOS1

5.83e-0634927799946
Pubmed

Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival.

SOS1 SOS2

5.83e-06349224043312
Pubmed

Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.

PTPRD PTPRS

5.83e-06349233656439
Pubmed

Distribution of glutamate transporters in the human placenta.

SLC1A1 SLC1A3

5.83e-06349215135231
Pubmed

Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex.

SLC1A1 SLC1A3

5.83e-0634927521911
Pubmed

Extracellular Prolidase (PEPD) Induces Anabolic Processes through EGFR, β1-integrin, and IGF-1R Signaling Pathways in an Experimental Model of Wounded Fibroblasts.

IGF1R ITGB1

5.83e-06349233477899
Pubmed

Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS.

SOS1 SOS2

5.83e-06349212628188
Pubmed

Facilitated activation of metabotropic glutamate receptors in cerebellar Purkinje cells in glutamate transporter EAAT4-deficient mice.

SLC1A1 SLC1A3

5.83e-06349217727989
Pubmed

Differential Role of the RasGEFs Sos1 and Sos2 in Mouse Skin Homeostasis and Carcinogenesis.

SOS1 SOS2

5.83e-06349229844066
Pubmed

Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion.

PTPRD PTPRS

5.83e-06349225394468
Pubmed

Glial glutamate transporter GLT-1 determines susceptibility to spreading depression in the mouse cerebral cortex.

SLC1A1 SLC1A3

5.83e-06349232585762
Pubmed

Alteration of the glutamate and GABA transporters in the hippocampus of the Niemann-Pick disease, type C mouse using proteomic analysis.

SLC1A1 SLC1A3

5.83e-06349216429462
Pubmed

Single exposure to cocaine impairs aspartate uptake in the pre-frontal cortex via dopamine D1-receptor dependent mechanisms.

SLC1A1 SLC1A3

5.83e-06349227208619
Pubmed

Molecular regulation of antioxidant ability in the hippocampus of EL mice.

SLC1A1 SLC1A3

5.83e-06349218621028
Pubmed

Conditional knockout of NaV1.6 in adult mice ameliorates neuropathic pain.

SCN8A SCN10A

5.83e-06349229497094
Pubmed

Dynamic changes in expression of glutamate transporter mRNAs in developing brain.

SLC1A1 SLC1A3

5.83e-0634928733726
Pubmed

Association study of polymorphisms in the glutamate transporter genes SLC1A1, SLC1A3, and SLC1A6 with schizophrenia.

SLC1A1 SLC1A3

5.83e-06349217221839
Pubmed

Upregulation of the Na⁺-coupled phosphate cotransporters NaPi-IIa and NaPi-IIb by B-RAF.

SLC34A1 SLC34A2

5.83e-06349224258620
Pubmed

Functional roles of high-affinity glutamate transporters in cochlear afferent synaptic transmission in the mouse.

SLC1A1 SLC1A3

5.83e-06349220220082
Pubmed

JAK2 regulates Nav1.6 channel function via FGF14Y158 phosphorylation.

SCN8A FGF14

5.83e-06349232599005
Pubmed

Deconstructing Ras signaling in the thymus.

SOS1 SOS2

5.83e-06349222586275
Pubmed

Interleukin-1 attenuates normal tension glaucoma-like retinal degeneration in EAAC1-deficient mice.

SLC1A1 SLC1A3

5.83e-06349219766171
Pubmed

Phosphoenolpyruvate-dependent inhibition of collagen biosynthesis, alpha2beta1 integrin and IGF-I receptor signaling in cultured fibroblasts.

IGF1R ITGB1

5.83e-06349218491034
Pubmed

Disassembly of Son-of-sevenless proteins from Grb2 during p21ras desensitization by insulin.

SOS1 SOS2

5.83e-0634927829473
Pubmed

Differential interactions of human Sos1 and Sos2 with Grb2.

SOS1 SOS2

5.83e-0634927629138
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

SLCO2B1 CYP4F2 CYP4F3 ALDH1L1 ABCG5

7.81e-0619349519343046
Pubmed

Expression of Glutamate Transporters in Mouse Liver, Kidney, and Intestine.

SLC1A1 SLC1A3

1.16e-05449229303644
Pubmed

SIRPα Mediates IGF1 Receptor in Cardiomyopathy Induced by Chronic Kidney Disease.

IGF1R SIRPB1

1.16e-05449235722884
Pubmed

Gene expression of glutamate transporters SLC1A1, SLC1A3 and SLC1A6 in the cerebellar subregions of elderly schizophrenia patients and effects of antipsychotic treatment.

SLC1A1 SLC1A3

1.16e-05449222424243
Pubmed

Astrocyte glutamate transporters regulate metabotropic glutamate receptor-mediated excitation of hippocampal interneurons.

SLC1A1 SLC1A3

1.16e-05449215140926
Pubmed

Semi-quantitative distribution of excitatory amino acid (glutamate) transporters 1-3 (EAAT1-3) and the cystine-glutamate exchanger (xCT) in the adult murine spinal cord.

SLC1A1 SLC1A3

1.16e-05449232768484
Pubmed

Identifying a kinase network regulating FGF14:Nav1.6 complex assembly using split-luciferase complementation.

SCN8A FGF14

1.16e-05449225659151
Pubmed

The sodium phosphate cotransporter family and nicotinamide phosphoribosyltransferase contribute to the daily oscillation of plasma inorganic phosphate concentration.

SLC34A1 SLC34A2

1.16e-05449229398136
Pubmed

Targeted deletion of the tybe IIb Na(+)-dependent Pi-co-transporter, NaPi-IIb, results in early embryonic lethality.

SLC34A1 SLC34A2

1.16e-05449219233126
Pubmed

Platelet-Rich Plasma Promotes the Proliferation of Human Keratinocytes via a Progression of the Cell Cycle. A Role of Prolidase.

IGF1R ITGB1

1.16e-05449233477820
Pubmed

High-density presynaptic transporters are required for glutamate removal from the first visual synapse.

SLC1A1 SLC1A3

1.16e-05449216600856
Pubmed

Caveolin-1 Sensitivity of Excitatory Amino Acid Transporters EAAT1, EAAT2, EAAT3, and EAAT4.

SLC1A1 SLC1A3

1.16e-05449226690923
Pubmed

A new member of the amphiphysin family connecting endocytosis and signal transduction pathways.

SOS1 SOS2

1.16e-0544929182529
Pubmed

The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.

PTPRD PTPRS

1.16e-0544928524829
Pubmed

Structure and functional expression of the cloned mouse neuronal high-affinity glutamate transporter.

SLC1A1 SLC1A3

1.16e-0544929379843
Pubmed

Alternative ZAP70-p38 signals prime a classical p38 pathway through LAT and SOS to support regulatory T cell differentiation.

SOS1 SOS2

1.16e-05449231337738
Pubmed

Engagement of the T lymphocyte antigen receptor regulates association of son-of-sevenless homologues with the SH3 domain of phospholipase Cgamma1.

SOS1 SOS2

1.16e-05449210940929
Pubmed

Insulin and Insulin-Like Growth Factor 1 Signaling Preserves Sarcomere Integrity in the Adult Heart.

IGF1R ITGB1

1.94e-05549236125265
Pubmed

Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development.

SOS1 SOS2

1.94e-0554929030684
Pubmed

Changes in expression and distribution of the glutamate transporter EAAT4 in developing mouse Purkinje cells.

SLC1A1 SLC1A3

1.94e-0554929129177
Pubmed

Multiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine phosphatase domains of various RPTPs.

PTPRD PTPRS

1.94e-05549210777529
Pubmed

Decorin regulates endothelial cell motility on collagen I through activation of insulin-like growth factor I receptor and modulation of alpha2beta1 integrin activity.

IGF1R ITGB1

1.94e-05549218413316
Pubmed

Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule.

PTPRD PTPRS

1.94e-05549222357843
Pubmed

A phospholipase C-γ1-independent, RasGRP1-ERK-dependent pathway drives lymphoproliferative disease in linker for activation of T cells-Y136F mutant mice.

SOS1 SOS2

1.94e-05549223209318
InteractionOPALIN interactions

TMEM161A PTPRD AHCTF1 LPCAT4 SLC1A1 ATP2B4

9.88e-06209486int:OPALIN
Cytoband2p21

KCNG3 ABCG5 SOS1

3.94e-05614932p21
CytobandEnsembl 112 genes in cytogenetic band chr19p13

TMEM161A PTPRS CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.99e-04797496chr19p13
Cytoband19p13.1

CYP4F12 CYP4F11

1.22e-034849219p13.1
CytobandEnsembl 112 genes in cytogenetic band chr2p21

KCNG3 ABCG5

3.34e-0380492chr2p21
GeneFamilyCytochrome P450 family 4

CYP4F2 CYP4F3 CYP4F12 CYP4F11

9.31e-07363841003
GeneFamilySolute carriers

SLC38A1 SLC34A1 SLCO2B1 SLC6A5 SLC34A2 SLC10A3 SLC1A1 SLC1A3

1.33e-06395388752
GeneFamilySodium voltage-gated channel alpha subunits

SCN8A SCN10A

1.53e-0493821203
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

LRIT2 PTPRD PTPRS SPEG

3.53e-04161384593
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRD PTPRS

8.81e-0421382813
GeneFamilyADAM metallopeptidase domain containing|CD molecules

IGF1R LAMP3 CD46 SIRPB1 ITGB1

1.33e-03394385471
GeneFamilyC1-set domain containing

HLA-B SIRPB1

3.51e-0342382591
GeneFamilyHistocompatibility complex|C1-set domain containing

HLA-B HLA-H

3.85e-0344382588
GeneFamilyFibronectin type III domain containing

IGF1R PTPRD PTPRS

4.57e-03160383555
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SOS1 SOS2

8.48e-0366382722
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

SLC38A1 TMEM161A IGF1R GANAB HLA-B PTPRS HLA-H TMEM63B SLC10A3 ITGB1

5.77e-077034910MM1055
CoexpressionMILI_PSEUDOPODIA_CHEMOTAXIS_DN

IGF1R GANAB HLA-B PTPRS AHCTF1 HLA-H SLC10A3 ITGB1

2.38e-06470498MM1053
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

SLC38A1 TMEM161A IGF1R GANAB HLA-B PTPRS TMEM63B SLC10A3 ITGB1

4.15e-06681499M5314
CoexpressionSAENZ_DETOX_PATHWAY_AND_CARCINOGENESIS_DN

CYP4F2 CYP4F12 CYP4F11

6.84e-0620493MM1104
CoexpressionWOO_LIVER_CANCER_RECURRENCE_DN

CYP4F2 CYP4F3 CYP4F12 ALDH1L1

1.39e-0578494M9911
CoexpressionGSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_DN

ADAM19 HLA-H ITGB1 ATP2B4 SOS2

2.16e-05180495M6317
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4

PTPRD HLA-B HLA-H CYP4F2 CYP4F12 CYP4F11

3.37e-05330496MM1120
CoexpressionTABULA_MURIS_SENIS_SPLEEN_B_CELL_AGEING

HLA-B HLA-H CYP4F3 ITGB1

5.57e-05111494MM3831
CoexpressionTABULA_MURIS_SENIS_KIDNEY_KIDNEY_DISTAL_CONVOLUTED_TUBULE_EPITHELIAL_CELL_AGEING

HLA-B SLC34A1 HLA-H IFI27

8.57e-05124494MM3726
CoexpressionTABULA_MURIS_SENIS_LIVER_HEPATOCYTE_AGEING

HLA-B HLA-H ALDH1L1 IFI27

1.65e-04147494MM3753
CoexpressionMILI_PSEUDOPODIA_CHEMOTAXIS_DN

IGF1R GANAB PTPRS AHCTF1 SLC10A3 ITGB1

2.02e-04457496M1613
CoexpressionDESCARTES_FETAL_KIDNEY_METANEPHRIC_CELLS

SLC34A1 SLC6A5 SLC34A2 KCNG3

2.13e-04157494M40223
CoexpressionNFE2L2.V2

PTPRD SLCO2B1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.32e-04469496M2870
CoexpressionJONES_OVARY_ENDOTHELIAL

HLA-B SLCO2B1 IFI27 ITGB1

2.40e-04162494M48350
CoexpressionDURAND_STROMA_S_UP

ADAM19 SPEG IFI27 SLC1A3 TMEM121

2.40e-04300495M2581
CoexpressionDURAND_STROMA_S_UP

ADAM19 SPEG IFI27 SLC1A3 TMEM121

2.55e-04304495MM1083
CoexpressionGSE3920_UNTREATED_VS_IFNG_TREATED_FIBROBLAST_UP

ADAM19 LPCAT4 KCNG3 ITGB1

2.63e-04166494M6688
CoexpressionTAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP

SLC38A1 ADAM19 LAMP3 IFI27

3.29e-04176494M15588
CoexpressionCHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN

CYP4F2 CYP4F3 ALDH1L1 CYP4F11

3.51e-04179494M16932
CoexpressionDESCARTES_FETAL_ADRENAL_MYELOID_CELLS

SLCO2B1 TRPM2 SIRPB1 SLC1A3

3.97e-04185494M40148
CoexpressionTABULA_MURIS_SENIS_LUNG_ENDOTHELIAL_CELL_OF_LYMPHATIC_VESSEL_AGEING

HLA-B HLA-H

4.04e-0416492MM3766
CoexpressionGSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_UP

GANAB SCN10A CYP4F3 ABCG5

4.22e-04188494M3300
CoexpressionSERVITJA_LIVER_HNF1A_TARGETS_DN

CYP4F2 CYP4F12 ALDH1L1 CYP4F11

4.39e-04190494MM1311
CoexpressionGSE29615_CTRL_VS_LAIV_FLU_VACCINE_PBMC_UP

LAMP3 CYP4F2 CYP4F3 IFI27

4.57e-04192494M4923
CoexpressionDESCARTES_ORGANOGENESIS_HEPATOCYTES

HLA-B HLA-H CYP4F2 CYP4F12 KCNG3 CYP4F11

4.67e-04535496MM3635
CoexpressionP53_DN.V1_UP

LPCAT4 LAMP3 IFI27 ME3

4.75e-04194494M2698
CoexpressionGSE3400_UNTREATED_VS_IFNB_TREATED_MEF_DN

PTPRD HLA-B FGF14 ME3

4.75e-04194494M6134
CoexpressionLTE2_UP.V1_DN

IGF1R LAMP3 IFI27 SLC1A1

4.84e-04195494M2721
CoexpressionGSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP

CYP4F2 CYP4F3 CD46 SOS2

4.94e-04196494M5349
CoexpressionTABULA_MURIS_SENIS_KIDNEY_KIDNEY_PROXIMAL_CONVOLUTED_TUBULE_EPITHELIAL_CELL_AGEING

HLA-B HLA-H SIRPB1 IFI27

4.94e-04196494MM3730
CoexpressionSHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4

SLC34A2 DAAM2 ATP2B4 ME3

5.03e-04197494M12824
CoexpressionGSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_UP

AHCTF1 LAMP3 CD46 ATP2B4

5.03e-04197494M9969
CoexpressionGSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN

ADAM19 IFI27 ITGB1 ATP2B4

5.03e-04197494M3105
CoexpressionGSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_DN

LAMP3 IFI27 SLC1A1 CYP4F11

5.13e-04198494M3302
CoexpressionGSE37534_GW1929_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_UP

HLA-B PTPRS CYP4F2 IFI27

5.13e-04198494M8985
CoexpressionGSE3982_MAC_VS_NKCELL_DN

PTPRD HLA-B SLC10A3 ATP2B4

5.13e-04198494M5509
CoexpressionGSE1925_CTRL_VS_3H_IFNG_STIM_MACROPHAGE_DN

SLC34A1 SCN10A SLC34A2 CYP4F11

5.23e-04199494M6290
CoexpressionGSE42021_TREG_PLN_VS_TREG_PRECURSORS_THYMUS_DN

HLA-B LAMP3 IFI27 CYP4F11

5.33e-04200494M9570
CoexpressionGSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_UP

HLA-B TRPM2 CYP4F3 ITGB1

5.33e-04200494M8569
CoexpressionGSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_UP

CFAP54 TMEM63B MFSD2B SLC34A2

5.33e-04200494M7198
CoexpressionGSE46606_IRF4_KO_VS_WT_UNSTIM_BCELL_DN

HLA-B TRPM2 SLC34A2 SIRPB1

5.33e-04200494M9861
CoexpressionGSE7852_TREG_VS_TCONV_THYMUS_UP

IGF1R HLA-B PTPRS ITGB1

5.33e-04200494M5730
CoexpressionGSE7460_TCONV_VS_TREG_THYMUS_DN

ADAM19 HLA-B PTPRS ITGB1

5.33e-04200494M5676
CoexpressionYAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9

HLA-B HLA-H SLC1A1

5.44e-0485493MM1279
CoexpressionWUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_DN

HLA-B HLA-H

5.74e-0419492MM797
CoexpressionMIKKELSEN_NPC_ICP_WITH_H3K27ME3

HLA-B HLA-H

5.74e-0419492MM862
CoexpressionZENG_GU_POST_ICB_METAGENE_39

SLC34A2 CYP4F2 CYP4F12 CYP4F11

5.74e-04204494MM17090
CoexpressionLEE_CALORIE_RESTRICTION_NEOCORTEX_UP

PTPRD HLA-B HLA-H

5.83e-0487493MM652
CoexpressionTABULA_MURIS_SENIS_BLADDER_LEUKOCYTE_AGEING

HLA-B HLA-H

6.37e-0420492MM3682
CoexpressionFAN_EMBRYONIC_CTX_MICROGLIA_3

SLCO2B1 SLC1A3

6.37e-0420492M39043
CoexpressionTABULA_MURIS_SENIS_LUNG_B_CELL_AGEING

HLA-B HLA-H ITGB1

6.43e-0490493MM3756
CoexpressionTABULA_MURIS_SENIS_LIMB_MUSCLE_SMOOTH_MUSCLE_CELL_AGEING

HLA-B HLA-H ITGB1

6.86e-0492493MM3748
CoexpressionRUAN_RESPONSE_TO_TNF_UP

HLA-B HLA-H

7.03e-0421492MM651
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAAM2 CYP4F3 CYP4F12 ALDH1L1 SLC1A3

1.44e-061764952bc4d3ddc2f752d8255dec0e7a9b87c7f82a372d
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLCO2B1 TRPM2 LAMP3 MFSD2B SLC1A3

1.65e-0618149579102845baee5af583eec24e9f91dfec46ab7de3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC34A1 CYP4F2 CYP4F3 ALDH1L1 SLC1A1

1.74e-06183495facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAAM2 CYP4F12 ALDH1L1 CYP4F11 SLC1A3

1.79e-0618449522c18964818fc9c8f18051f836d718937b0d8d12
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD SLC34A1 CYP4F3 ALDH1L1 SLC1A1

1.93e-06187495dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD SLC34A1 CYP4F3 ALDH1L1 SLC1A1

1.93e-06187495f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellBAL|World / Compartment, Disease Groups and Clusters

ADAM19 SLCO2B1 LAMP3 IFI27 SLC1A3

2.37e-06195495f59faf77fc7d7fd7ddb9d4d6d469951d5066bebb
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-CD1c+_DCs|Myeloid_cells / Location, Cell class and cell subclass

SLC38A1 ADAM19 LAMP3 FGF14

2.81e-05159494b3c52908cd24bbf851fac69db3850fc7f53c2092
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

TMEM63B LAMP3 SLC34A2 DAAM2

3.17e-05164494beaa13a75c3bb72446c85084d75e9fe3f15fd3d4
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRPM2 TMEM63B LAMP3 SLC34A2

3.17e-05164494fe11fcce4ba7f44ba2989ea3705916b67e75f8e7
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRPM2 TMEM63B LAMP3 SLC34A2

3.17e-05164494b6beb8548ac0dd07e8a580a938e5ee4bf25a3c1f
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|E18.5-samps / Age Group, Lineage, Cell class and subclass

PTPRD PTPRS MFSD2B ATP2B4

3.17e-05164494519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

TMEM63B LAMP3 SLC34A2 DAAM2

3.17e-05164494d005cfd821b87548b075120bffe65a0be9860463
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-cDC2|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM19 TRPM2 LAMP3 SLC1A3

3.41e-051674941bd0aa7a3c8649f342bb856cf861c4c5984ad889
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD SLC34A1 CYP4F3 ALDH1L1

3.49e-05168494fa0d251693935116adf633d02b7ec4a295100865
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD SLC34A1 CYP4F3 SLC1A1

3.91e-051734948888434641ea554a9b62c436e87920378eef29cd
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

SLC38A1 ADAM19 HLA-B CD46

4.27e-0517749482fdd6185b368f54f03de389427cbe3071d21a99
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC34A1 CYP4F3 ALDH1L1 SLC1A1

4.37e-0517849423a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCellBAL-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC38A1 CFAP54 ADAM19 ATP2B4

4.46e-05179494a634ca46ffc394c5f5215fc5d8eae4a77819af9c
ToppCellBAL-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC38A1 CFAP54 ADAM19 ATP2B4

4.46e-0517949435f014b6e752626909d829c5ab9bb761c1f3e3dc
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Macrophage|lymph-node_spleen / Manually curated celltypes from each tissue

SLCO2B1 SCN10A IFI27 SLC1A3

4.46e-05179494b4430f633711cecf793e8e76e766a66ff1eff473
ToppCellCOPD-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

SLC38A1 ADAM19 PTPRS TRPM2

4.46e-0517949429b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC34A1 CYP4F3 ALDH1L1 SLC1A1

4.56e-05180494f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PTPRD CYP4F3 ALDH1L1 SLC1A1

4.56e-05180494358923e4228035a3e90e2957392089219e90dcd7
ToppCellControl-Myeloid-Dendritic_cells|Control / group, cell type (main and fine annotations)

ADAM19 SLCO2B1 TRPM2 SLC1A3

4.56e-0518049425ad95c3c30e3b82abe93bd77ba003f5c2241f7c
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

PTPRD CYP4F3 ALDH1L1 SLC1A1

4.56e-05180494864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TMEM63B LAMP3 SLC34A2 CD46

4.66e-05181494576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD SLC34A1 CYP4F3 SLC1A1

4.76e-05182494e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLCO2B1 TRPM2 SIRPB1 SLC1A3

4.76e-05182494ea39b1b5db185b0cb11dfa2e01f3f972effbd770
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD SLC34A1 CYP4F3 SLC1A1

4.76e-0518249457bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 CFAP54 ALDH1L1 SLC1A3

4.97e-051844946b0c110d8930df99043c3b99cf4d873985126960
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 CFAP54 ALDH1L1 SLC1A3

4.97e-0518449435928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCellCOVID-19-kidney-PCT-S1/S2|kidney / Disease (COVID-19 only), tissue and cell type

PTPRD SLC34A1 CYP4F3 SLC1A1

4.97e-05184494dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

SLC38A1 ADAM19 AHCTF1 CD46

5.07e-05185494a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC34A1 CYP4F3 ALDH1L1 SLC1A1

5.07e-051854941bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAAM2 ALDH1L1 CYP4F11 SLC1A3

5.18e-0518649473cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HLA-B SLCO2B1 HLA-H IFI27

5.18e-05186494422d24e3e1a9397bb7d5c7ef75de2fd7ae8e136d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD SLC34A1 CYP4F3 ALDH1L1

5.18e-051864948287146f0ba415ea04475588117d4668ae00f75c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD CYP4F3 ALDH1L1 SLC1A1

5.18e-05186494a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PTPRD LAMP3 SLC34A2 CD46

5.18e-05186494acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HLA-B SLCO2B1 HLA-H IFI27

5.18e-0518649465da0666a10a59f8cc379589860a2e98fe487754
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HLA-B SLCO2B1 HLA-H IFI27

5.18e-05186494dc84fef1ca2f5d5d818b76a3321559e87d1c4a4d
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM132E CYP4F2 SLC1A1 ABCG5

5.29e-051874949042bd0f57213a51503d9df2e4dce3209b7772d3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD CYP4F3 ALDH1L1 SLC1A1

5.29e-051874941b82920588f9e26ef1db244d452736d75fcfd342
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD SLC34A1 CYP4F3 ALDH1L1

5.29e-0518749471eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAAM2 ALDH1L1 CYP4F11 SLC1A3

5.29e-051874942b1b2c3792d6c9ab69675ce88842bb589414b530
ToppCelldroplet-Kidney-nan-18m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRD SLC34A1 ALDH1L1 SLC1A1

5.29e-05187494236e9857729670e87eed30fad58f49e1f56e4a85
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD CYP4F3 ALDH1L1 SLC1A1

5.29e-05187494c1e4c0345f9bfa0538730bad5ff3fa5240168b25
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 TRPM2 SCN8A SLC6A5

5.40e-051884941efbc99bcd6542e5d9fa91edb7c4295167914786
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD SLC34A1 CYP4F3 SLC1A1

5.40e-05188494f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD SLC34A1 CYP4F3 SLC1A1

5.40e-051884940792432cd4c564dea1102241ea9884f7ced7658c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD SLC34A1 CYP4F3 SLC1A1

5.51e-05189494204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD SLC34A1 CYP4F3 SLC1A1

5.51e-0518949413fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRS SPEG DAAM2 FGF14

5.51e-0518949445e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAAM2 ALDH1L1 CYP4F11 SLC1A3

5.63e-0519049478cc6c28b31de041c24175a98f47da256ecc15a2
ToppCellBAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC38A1 ADAM19 HLA-B LAMP3

5.63e-0519049455df73c8b696967a925b1772631f6900eff0fa30
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLCO2B1 TRPM2 DAAM2 SLC1A3

5.63e-051904942d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCellpdx-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SLCO2B1 CYP4F3 CYP4F12 ABCG5

5.63e-05190494b05db0de9b6ae01dd30074453f7de44f7397631e
ToppCellBAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC38A1 ADAM19 HLA-B LAMP3

5.63e-05190494494fbab37305a7f92cddec75b291d42282555f5f
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAAM2 ALDH1L1 CYP4F11 SLC1A3

5.63e-05190494e67d9400467b438592690b23d681e6c2fb8f09fd
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRS SPEG DAAM2 SLC1A3

5.74e-0519149414057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

SLC38A1 ADAM19 AHCTF1 CD46

5.74e-051914949454f642c3621370fa23640b631301346b300950
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TMEM63B LAMP3 SLC34A2 SLC1A1

5.74e-05191494ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellhuman_hepatoblastoma-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SLCO2B1 CYP4F3 CYP4F12 ABCG5

5.86e-05192494e785135262f4c9cc66c403bf362bb34643b212c5
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SLC38A1 LAMP3 IFI27 ITGB1

5.86e-05192494e07b6892276c81c1227e94ca942f6820d89a7ca3
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMH+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-B IFI27 ITGB1 ATP2B4

5.86e-05192494fdc741e1846cfd8ed741b160e3c611c310c5d36d
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMH+-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-B IFI27 ITGB1 ATP2B4

5.86e-051924940f8c63de26128694f4522f9f6d029e4628c890bc
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SLC38A1 LAMP3 IFI27 ITGB1

6.10e-051944940b0042b6a356a49a059fb64a1e1abb25c82d48cf
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRD PTPRS CYP39A1 SLC1A3

6.10e-0519449460622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellLA-08._Macrophage|LA / Chamber and Cluster_Paper

SLCO2B1 TRPM2 DAAM2 SLC1A3

6.22e-051954945e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCellfacs-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLCO2B1 LAMP3 SLC34A2 ITGB1

6.22e-05195494c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCell3'-Child09-12|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-B CYP4F2 IFI27 SLC1A1

6.35e-051964941bcc4ffff51cdb6211824686c2422c43b09e24b2
ToppCell(7)_Epithelial-I_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

TMEM63B SLC34A2 IFI27 SLC1A1

6.35e-05196494150554fa06868d29b0608189862eef6505ba757f
ToppCellControl_saline-Epithelial_alveolar-AT_2-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

SLC38A1 TMEM63B LAMP3 SLC34A2

6.47e-0519749444a59dfb889577b3160a5b13ada1276771a00241
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 SLCO2B1 TRPM2 SLC1A3

6.47e-05197494c9b1f2ee7eb31a66af331c5aae29e1bbb5186f5a
ToppCellControl-Lymphoid-CD4_T_cells|Control / Condition, Lineage and Cell class

SLC38A1 ADAM19 HLA-B ATP2B4

6.47e-05197494dad6479caac07c1536f2b3082a51d61ae08beca0
ToppCellBAL-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC38A1 ADAM19 LAMP3 ATP2B4

6.47e-05197494927bf36bad3bcb7346c13b660777c1c0de7dc322
ToppCellBAL-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC38A1 ADAM19 LAMP3 ATP2B4

6.47e-051974943e09158507df08c08e08613ce23617206280c911
ToppCellMonocytes-Phagocytic_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

SLCO2B1 SIRPB1 IFI27 SLC1A3

6.60e-0519849409009cc966bf1503c3b15dfa079a6c5f6ad1f507
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Trm_Th1/Th17|Lung / Manually curated celltypes from each tissue

ADAM19 HLA-B LPCAT4 ATP2B4

6.73e-051994941acf522a5d296042fe9f1cb47c1a06fc22da75a3
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_CHIT1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SLCO2B1 TRPM2 SIRPB1 SLC1A3

6.73e-05199494368e2bafae00ce8e9c6ea480f81b78f96b680acd
ToppCellControl-Control-Lymphocyte-T/NK-CD8+_Tem|Control / Disease, condition lineage and cell class

SLC38A1 HLA-B ITGB1 ATP2B4

6.86e-05200494fddb3df5b90eb97ef8ed80fac320c1a90903f012
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Calb2|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC34A1 SCN10A KCNG3

9.06e-057949303c5af851b53800eced1c74e9da374c71092bcd4
ToppCellBronchial_Biopsy-Endothelial-Endothelial|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X

HLA-B IFI27

2.65e-0422492124067c169b11131084e634b8c29fd855b8eb231
ToppCellVE-CD4-CD8_2|VE / Condition, Cell_class and T cell subcluster

IGF1R SPEG IQUB

3.27e-041224936745035feaf807b6a6b9537ac9d5ee0e000196eb
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_B3|TCGA-Thymus / Sample_Type by Project: Shred V9

SLC34A1 SLC10A3 CYP4F12

3.85e-04129493c760a1f9b86f086074e6e04e50ab40da3639e5fb
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-DC2|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CYP4F2 KCNG3 CYP39A1

4.89e-04140493c3331cb7720f93af8bab35d02c6cbe87dd324d91
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma-4|TCGA-Cervix / Sample_Type by Project: Shred V9

CFAP54 BBS1 IQUB

5.10e-04142493369f2e51e0283a4de70e6c7a3b95672c0838f205
ToppCellEpithelial-B_(AT1-AT2-progenitors)|World / shred on cell class and cell subclass (v4)

LRIT2 LAMP3 SLC34A2

5.53e-041464934511916904c1fac252cb68e871b782207f8137b3
ToppCellmetastatic_Brain-T/NK_cells-Naive_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

PTPRD SPEG BBS1

5.64e-041474934f7a0c287721befeffabf95b8c5f9ff64149c7c1
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT1_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC34A1 LAMP3 SLC34A2

5.64e-04147493a82a971a934faff6806823ca62a398b429ecd9c8
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-Trm_Th1/Th17|bone_marrow / Manually curated celltypes from each tissue

ADAM19 ABCG5 TMEM121

5.87e-04149493264fe2ceac6379b3394d2bb47ef34692e4a64559
ToppCellremission-multiplets|remission / disease stage, cell group and cell class

MFSD2B DAAM2 CYP4F3

5.87e-04149493e9974260a5f2999b363f306cae005698c912893a
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1R ADAM19 TRPM2

5.98e-041504936e806a028c0519489151c181d9907e05289e27e0
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CFAP54 GANAB SPEG

5.98e-04150493b6f1fc62d08199fed6156c7cd32f66d9926531b5
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HLA-B CYP39A1 ITGB1

6.33e-04153493764fb5e5fa028c137b8ea65dcd5e4ec9b22191e9
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC34A1 CYP4F2 CYP4F3

6.46e-0415449389a60a79d07466d7ad05888d10a72d3b1ab384af
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC34A1 CYP4F2 CYP4F3

6.46e-04154493f1fea1a87e977221fa125b62287368be9af4987d
ToppCellHealthy_donor-RBC|Healthy_donor / disease group, cell group and cell class (v2)

SPEG MFSD2B IFI27

6.46e-04154493e080d5104fe6f3f6ef617bbcdccf1332ab7231e1
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT4 MFSD2B CD46

6.46e-0415449375eac6970259a6916fcfa6d3400509cfa2d98d9d
ComputationalNeighborhood of GSTM1

CYP4F2 CYP4F12 ALDH1L1 CYP4F11

3.67e-04109344GNF2_GSTM1
ComputationalNeighborhood of LCAT

CYP4F2 CYP4F12 ALDH1L1 CYP4F11

5.99e-04124344GNF2_LCAT
ComputationalNeighborhood of HPN

CYP4F2 CYP4F12 ALDH1L1 CYP4F11

8.01e-04134344GNF2_HPN
ComputationalNeighborhood of HPX

CYP4F2 CYP4F12 ALDH1L1 CYP4F11

8.24e-04135344GNF2_HPX
Drugsodium

SLC38A1 SLC34A1 SLCO2B1 TRPM2 SLC6A5 SCN10A SLC34A2 SLC10A3 SLC1A1 SLC1A3 ATP2B4 SOS1 SOS2

6.46e-089444913CID000000923
Drugbumetanide

SLC34A1 SLCO2B1 SLC6A5 SLC34A2 SLC10A3 SLC1A1 SLC1A3

3.08e-07209497CID000002471
Drugpropoxyphene

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

3.27e-0767495CID000010100
Drugcarteolol

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

4.70e-0772495CID000002583
Drugarsenic pentoxide

SLC34A1 SLCO2B1 SLC34A2

5.21e-078493ctd:C042120
Drugtrimipramine

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

7.97e-0780495CID000005584
Drugdiosmetin

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

1.08e-0685495CID005281612
Drughydride

SLC34A1 CYP4F2 CYP4F12 ALDH1L1 CYP39A1 SLC1A1 CYP4F11 SLC1A3 ATP2B4 SOS1 SOS2

1.23e-068354911CID000000783
Drugmephenytoin

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

1.28e-0688495CID000004060
Drugtienilic acid

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

1.69e-0693495CID000038409
Druglansoprazole

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

1.69e-0693495CID000003883
Drugdichloran

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.81e-0641494CID000007430
DrugL-alanosine

SLC6A5 SLC1A1 SLC1A3 SOS2

1.81e-0641494CID000022128
DrugAC1L1KIN

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

2.42e-06100495CID000005516
DrugSparteinum

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

2.54e-06101495CID000003966
Drugalprazolam

CYP4F2 CYP4F3 CYP4F12 CYP39A1 SLC1A1 CYP4F11

3.54e-06193496CID000002118
DrugPropafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; MCF7; HT_HG-U133A

IGF1R SPEG DAAM2 ATP2B4 ABCG5 TMEM121

3.87e-061964962871_UP
Drugrifampicin

SLCO2B1 CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11 SLC1A3

3.92e-06306497CID005381226
Drugbetaine

SLC38A1 SLC6A5 ALDH1L1 ITGB1 SLC1A1 SLC1A3

4.35e-06200496CID000000247
DrugAC1Q7AUJ

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

5.23e-06117495CID000003303
Drug8-MOP

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

5.46e-06118495CID000004114
Drughexobarbital

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

7.82e-06127495CID000003608
Drugchloral hydrate

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

8.43e-06129495CID000002707
Drugsenkirkine

PTPRD SLCO2B1 CYP4F3 CYP4F12

9.03e-0661494ctd:C009238
Drugaminoglutethimide

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

1.13e-05137495CID000002145
Drugmethylisobutylamiloride

SLC34A1 SOS1 SOS2

1.21e-0521493CID000073314
Drugebastine

CYP4F2 CYP4F3 CYP4F12

2.08e-0525493CID000003191
DrugVerteporfin [129497-78-5]; Down 200; 2.8uM; HL60; HT_HG-U133A

SLC38A1 IGF1R GANAB ITGB1 ATP2B4

2.39e-051604956133_DN
Drugfurosemide

SLC34A1 SLC6A5 SLC34A2 SLC10A3 SLC1A1 SLC1A3

2.50e-05272496CID000003440
Drugparaoxon

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

2.69e-05164495CID000009395
DrugAPETx2 protein, Anthopleura elegantissima

SCN8A SCN10A

2.71e-054492ctd:C501880
DrugYVN

SLC1A1 SLC1A3

2.71e-054492CID009547990
Drugfelodipine

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

3.11e-05169495CID000003333
Drugaminopyrine

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

3.29e-05171495CID000006009
Drugsarcolysin

SLC38A1 SLC6A5 ITGB1 SLC1A1 SLC1A3

3.38e-05172495CID000004053
Drugalpha-(methylamino)isobutyric acid

SLC38A1 SLC1A1 SLC1A3

4.04e-0531493CID000075725
DrugHis-pro-dkp

SLC6A5 SLC1A1 SLC1A3

4.04e-0531493CID000065137
Drugcarbamazepine

HLA-B TRPM2 SCN10A CYP39A1 SLC1A1

4.09e-05179495CID000002554
Drugmetyrapone

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

4.09e-05179495CID000004174
Drugpotassium

SLC38A1 SLC6A5 SCN10A SLC10A3 KCNG3 SLC1A1 SLC1A3 ATP2B4 SOS1 SOS2

4.71e-0510084910CID000000813
Drugclofibrate

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11 ABCG5

5.28e-05311496CID000002796
Drugethylnylestradiol

IGF1R SLC34A1 SLC34A2 CYP4F2 CYP4F3 CYP4F12 IFI27 CYP39A1 CYP4F11 SLC1A3 ABCG5

5.57e-0512514911CID000003285
Drughalothane

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11 ATP2B4

5.57e-05314496CID000003562
Drugethyldichloroarsine

CD46 SLC1A1 SLC1A3

5.84e-0535493CID000011711
Drugpropafenone

SCN10A CYP4F2 CYP4F12 CYP39A1

5.89e-0598494CID000004932
DrugIndomethacin [53-86-1]; Down 200; 11.2uM; PC3; HT_HG-U133A

SPEG SCN8A ITGB1 ME3 SOS2

6.00e-051944955049_DN
DrugGlipizide [29094-61-9]; Up 200; 9uM; MCF7; HT_HG-U133A

IGF1R ALDH1L1 IFI27 CYP4F11 TMEM121

6.15e-051954954991_UP
DrugPrazosin hydrochloride [19237-84-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A

LPCAT4 LAMP3 IFI27 TMEM121 SOS2

6.15e-051954955416_DN
DrugPhentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A

SCN8A SCN10A DAAM2 CYP4F12 IFI27

6.30e-051964953971_UP
DrugHydrastine hydrochloride [5936-28-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A

TRPM2 SLC34A2 DAAM2 SLC1A3 SOS2

6.45e-051974952889_UP
Drug3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A

PTPRS SLC34A2 ALDH1L1 IFI27 SOS2

6.45e-051974954764_DN
DrugVigabatrin [60643-86-9]; Down 200; 31uM; MCF7; HT_HG-U133A

PTPRS LAMP3 IFI27 CYP4F11 SOS2

6.45e-051974955415_DN
DrugNSC98537

IGF1R CYP4F2 CYP4F3 CYP4F12 IFI27 CYP39A1 CYP4F11

6.45e-05473497CID000005410
DrugBucladesine sodium salt [16980-89-5]; Up 200; 7.8uM; PC3; HT_HG-U133A

IGF1R PTPRS SCN10A DAAM2 SOS2

6.61e-051984955886_UP
Drugtolbutamide

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

6.61e-05198495CID000005505
DrugAzacyclonol [115-46-8]; Down 200; 15uM; MCF7; HT_HG-U133A

LPCAT4 IFI27 ITGB1 CYP4F11 SOS2

6.61e-051984955398_DN
DrugAminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A

TRPM2 SCN8A SCN10A DAAM2 ATP2B4

6.77e-051994954748_UP
DrugEthoxyquin [91-53-2]; Up 200; 18.4uM; PC3; HT_HG-U133A

IGF1R SLCO2B1 SLC34A2 ALDH1L1 SOS2

6.77e-051994953764_UP
DrugAPETx1, Anthopleura elegantissima

SCN8A SCN10A

6.77e-056492ctd:C475726
Drugsipatrigine

SLC6A5 SLC1A1 SLC1A3

6.91e-0537493CID000060803
DrugAC1O5PIQ

CYP4F2 CYP4F3 CYP4F12

8.11e-0539493CID006438348
Drugdiclofenac

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

8.53e-05209495CID000003032
Drugdesvenlafaxine

SLC6A5 SLC1A1 SLC1A3

9.43e-0541493CID000125017
Drug3-hydroxystearate

CYP4F2 CYP4F12

9.46e-057492CID005282907
Drugdioxin

SLCO2B1 CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

9.66e-05347496CID000015625
Drugphenobarbital

SLCO2B1 CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

1.18e-04360496CID000004763
Drugbenzphetamine

CYP4F3 CYP4F12 CYP39A1 CYP4F11

1.25e-04119494CID000002341
Drug2,3-PDCA

SLC1A1 SLC1A3

1.26e-048492CID000127037
Drug2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate

SCN8A SCN10A

1.26e-048492ctd:C489827
DrugNADP(H

CYP4F2 CYP4F3 CYP4F12 ALDH1L1 CYP39A1 CYP4F11 ME3

1.27e-04527497CID000000930
Drugamoxapine

SLC6A5 SLC1A1 SLC1A3

1.33e-0446493CID000002170
Drugnaphthalene

SCN10A CYP4F12 CYP39A1 CYP4F11

1.42e-04123494CID000000931
DrugClofibric Acid

PTPRD SLCO2B1 CYP4F2 CD46 ALDH1L1 IFI27 ABCG5 ME3

1.47e-04727498ctd:D002995
DrugMirex

SLC38A1 SLC34A2 ABCG5

1.51e-0448493ctd:D008917
Drugheliotrine

PTPRD SLCO2B1 CYP4F3

1.51e-0448493ctd:C010178
Drug3 -hydroxypregn-5-en-20-one

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11

1.57e-04238495CID000001027
DrugPhosphates

SLC34A1 SLC34A2 ATP2B4

1.61e-0449493ctd:D010710
DrugLithocholic Acid

HLA-B LPCAT4 CYP39A1 ITGB1 ABCG5

1.63e-04240495ctd:D008095
DrugC7 5

SLC34A1 SLC34A2

2.02e-0410492CID004248455
Drug18-HETE

CYP4F2 CYP4F12

2.02e-0410492CID006442778
Drug9-hydroxybenzo(a)pyrene

CYP4F12 CYP39A1 CYP4F11

2.03e-0453493CID000028598
Drugnifedipine

CYP4F2 CYP4F3 CYP4F12 CYP39A1 CYP4F11 ATP2B4

2.55e-04415496CID000004485
Drug17-ODYA

CYP4F2 CYP4F3 CYP4F12

2.94e-0460493CID000001449
Drugpyrrolidine-2,4-dicarboxylate

SLC6A5 SLC1A1 SLC1A3

3.09e-0461493CID000003868
DrugBP-4,5-oxide

CYP4F12 CYP39A1 CYP4F11

3.09e-0461493CID000037786
Drugmethylglucamine

SLC38A1 SCN8A ATP2B4

3.24e-0462493CID000004049
DrugVerteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A

IGF1R GANAB CD46 ITGB1

3.45e-041554946817_DN
Drugazo analog I

CYP4F3 CYP4F12

3.49e-0413492CID006438575
Drug3-hydroxyhexadecanoic acid

CYP4F2 CYP4F12

3.49e-0413492CID000301590
Druganthglutin

SLC1A1 SLC1A3

3.49e-0413492CID000125748
DrugNO-711

SLC6A5 SLC1A1 SLC1A3

3.90e-0466493CID000004515
DrugVerteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A

IGF1R GANAB CD46 ITGB1

3.98e-041614943556_DN
Drugbioallethrin

SCN8A SCN10A

4.06e-0414492ctd:C018465
Drug7-BFC

CYP4F2 CYP4F12

4.06e-0414492CID000848780
DrugN-(2-chloroethyl)-N-ethyl-2-bromobenzylamine

SLC6A5 SLC1A1 SLC1A3

4.44e-0469493CID000003172
Drugaminotriazole

SLC38A1 CYP4F2 CYP4F12 ALDH1L1

4.57e-04167494CID000001639
DrugRo106-9920

SLC1A1 SLC1A3

4.68e-0415492CID003906779
Drugdiamidine

CYP4F2 CYP4F3

4.68e-0415492CID000008813
DrugBetamethasone-d5

IGF1R SLC34A1 SCN10A CYP4F2 CYP4F3 CD46 CYP4F12 CYP39A1 ITGB1 CYP4F11

4.82e-0413404910CID000003003
Drug1-aminobenzotriazole

CYP4F2 CYP4F3 CYP39A1

4.83e-0471493CID000001367
Diseaselow tension glaucoma (implicated_via_orthology)

SLC1A1 SLC1A3

2.69e-055492DOID:13544 (implicated_via_orthology)
Diseaseepisodic ataxia type 6 (implicated_via_orthology)

SLC1A1 SLC1A3

4.04e-056492DOID:0050994 (implicated_via_orthology)
Diseasehexadecenedioate (C16:1-DC) measurement

CYP4F2 CYP4F11

9.65e-059492EFO_0800562
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN8A SCN10A

1.21e-0410492DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN8A SCN10A

1.21e-0410492DOID:0080422 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SCN8A SCN10A SLC1A1 SLC1A3

1.57e-04163494DOID:1826 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN8A SCN10A

1.76e-0412492DOID:0060170 (implicated_via_orthology)
Diseaseunipolar depression, mood disorder, response to antidepressant

PTPRD SCN8A

2.43e-0414492EFO_0003761, EFO_0004247, GO_0036276
DiseaseEpilepsy, Cryptogenic

SCN8A SLC1A1 SLC1A3

3.48e-0482493C0086237
DiseaseAwakening Epilepsy

SCN8A SLC1A1 SLC1A3

3.48e-0482493C0751111
DiseaseAura

SCN8A SLC1A1 SLC1A3

3.48e-0482493C0236018
DiseaseNoonan-Like Syndrome With Loose Anagen Hair

SOS1 SOS2

4.54e-0419492C3501846
DiseaseCostello syndrome (disorder)

SOS1 SOS2

4.54e-0419492C0587248
DiseaseNoonan syndrome-like disorder with loose anagen hair

SOS1 SOS2

4.54e-0419492C1843181
DiseaseCardio-facio-cutaneous syndrome

SOS1 SOS2

4.54e-0419492C1275081
Diseasehypertension (biomarker_via_orthology)

IGF1R CYP4F2 CYP4F12 CYP4F11

5.51e-04227494DOID:10763 (biomarker_via_orthology)
DiseaseLEOPARD Syndrome

SOS1 SOS2

6.11e-0422492C0175704
DiseaseNoonan Syndrome

SOS1 SOS2

7.28e-0424492C0028326
Diseaseosteonecrosis

PTPRD CYP4F12

7.91e-0425492EFO_0004259
DiseaseLeft ventricular mass to end-diastolic volume ratio

IGF1R HLA-B

7.91e-0425492EFO_0010556
DiseaseBrain Diseases

SLC6A5 SLC1A1

7.91e-0425492C0006111
DiseaseEpilepsy

SCN8A SLC1A1 SLC1A3

7.98e-04109493C0014544
DiseaseEncephalopathies

SLC6A5 SLC1A1

9.23e-0427492C0085584
Diseaseazoospermia (implicated_via_orthology)

PTPRD PTPRS

9.23e-0427492DOID:14227 (implicated_via_orthology)
Diseasehyperthyroidism (biomarker_via_orthology)

IGF1R SLC34A1

9.93e-0428492DOID:7998 (biomarker_via_orthology)
DiseaseColorectal Carcinoma

ADAM19 PTPRD PTPRS CD46 ALDH1L1 IQUB

1.04e-03702496C0009402
Diseasenon-high density lipoprotein cholesterol measurement

SLC38A1 HLA-B SLC34A1 HLA-H BBS1 CYP4F12

1.13e-03713496EFO_0005689
Diseasecreatinine measurement

IGF1R SLC34A1 SPEG ALDH1L1 SLC1A3 ABCG5 SOS2

1.21e-03995497EFO_0004518
Diseaseclopidogrel metabolite measurement

TMEM132E ATP2B4

1.38e-0333492EFO_0007966
Diseasepeak expiratory flow

IGF1R ADAM19 HLA-B ABCG5 ME3

1.39e-03498495EFO_0009718
DiseaseQRS duration

SLC38A1 IGF1R PTPRD SCN10A

1.51e-03298494EFO_0005055
Diseasetriacylglycerol 58:8 measurement

TMEM132E AHCTF1

1.55e-0335492EFO_0010442
Diseasephospholipid measurement

SLC38A1 CFAP54 HLA-B

1.64e-03140493EFO_0004639

Protein segments in the cluster

PeptideGeneStartEntry
VQILIKCIVVLQGLP

CFAP54

1171

Q96N23
GPVVAGVLVAILVLA

ADAM19

701

Q9H013
IIGITVLVVAVPEGL

ATP2B4

411

P23634
PIVAGVVAGIVLIGL

ITGB1

731

P05556
VPIVGIVAGLVLLVA

HLA-H

306

P01893
GVCVVSGIVLLALPI

KCNG3

391

Q8TAE7
KVAVLEILGAVCLVP

DAAM2

216

Q86T65
VVLPLARIATVVIGG

IFI27

26

P40305
VIAIVVGVAVICVVP

CD46

351

P15529
FVGSLPVIVVGRLKV

LPCAT4

306

Q643R3
VTVVLCVVLLAVPVG

LRIT2

466

A6NDA9
LIIALPVAVLLIVGG

IGF1R

936

P08069
VLVGITVPLVGLLVG

SLC10A3

386

P09131
LIPVGLRVVAIQGVK

FGF14

106

Q92915
TIVLPVIGAIVVGLC

LAMP3

381

Q9UQV4
EEVVVTLKVLIGAVP

MFSD2B

451

A6NFX1
VPIVGIVAGLAVLAV

HLA-B

306

P01889
VIGPVLAVVFIICIV

PTPRS

1286

Q13332
PVAGLVVGILVTVLV

SLC34A1

146

Q06495
VIGIIIVIIIHPGKG

SLC1A3

136

P43003
GRVIPKGIVCLINII

CYP4F11

411

Q9HBI6
GRVIPKGITCLIDII

CYP4F12

411

Q9HCS2
LLVVVGVLSVGIVLP

TMEM63B

161

Q5T3F8
IPALVILGIVVFKIR

ABCG5

631

Q9H222
GRVIPKGIICLISVF

CYP4F2

411

P78329
EVVRLVKPTAIIGVA

ME3

401

Q16798
ATVKVVLIPVGQEIV

IQUB

131

Q8NA54
PGVITRKVVKPVEIL

CYP39A1

341

Q9NYL5
GRVIPKGIICLISVF

CYP4F3

411

Q08477
VVKAVVLPGRVTAIE

AHCTF1

116

Q8WYP5
QPVGLIRVHKVLVVG

BBS1

291

Q8NFJ9
VILGIVLVVSIKPGV

SLC1A1

106

P43005
VGPVLAVVFIICIVI

PTPRD

1271

P23468
IPIIKGGTVVKLIER

SOS2

596

Q07890
VAIPVKVIAIEVNGL

TMEM132E

461

Q6IEE7
PVAKLAIRVGLAVVG

TMEM161A

221

Q9NX61
VVLVILLIRGVTLPG

SLC6A5

431

Q9Y345
RVVIIGAGKPAAVVL

GANAB

891

Q14697
AGIPIIKAGTVIKLI

SOS1

596

Q07889
LLGPKVLLVVGVSVI

SIRPB1

376

Q5TFQ8
LTLTRKEPVGVCGII

ALDH1L1

556

O75891
VGVGVPVVFIIILVL

SLC34A2

556

O95436
VVVAPGADVLLKCII

SPEG

731

Q15772
VIVGIVVGGVLVKRL

SLCO2B1

421

O94956
VSVIPGLKVIVGALI

SCN10A

226

Q9Y5Y9
RGGVAIKIPIVCVVL

TRPM2

316

O94759
PRKIGVCIIVLVGDV

TMEM121

36

Q9BTD3
ISVIPGLKTIVGALI

SCN8A

231

Q9UQD0
VLVVIVTFGIILPLC

SLC38A1

196

Q9H2H9