Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	GLUD1 GLUD2	1.09e-04	2	209	2	GO:0016639
GeneOntologyMolecularFunction	glutamate dehydrogenase [NAD(P)+] activity	GLUD1 GLUD2	1.09e-04	2	209	2	GO:0004353
GeneOntologyMolecularFunction	glutamate dehydrogenase (NAD+) activity	GLUD1 GLUD2	1.09e-04	2	209	2	GO:0004352
GeneOntologyMolecularFunction	glutamate dehydrogenase (NADP+) activity	GLUD1 GLUD2	1.09e-04	2	209	2	GO:0004354
GeneOntologyMolecularFunction	GTPase activator activity	SIPA1L3 ANKRD27 DOCK5 TBC1D1 ELMOD1 ARHGEF12 ARFGEF1 DNM1L TBCK RACGAP1 NCKAP1L	1.81e-04	279	209	11	GO:0005096
GeneOntologyMolecularFunction	nuclear retinoic acid receptor binding	PRAMEF5 PRAMEF26 PRAMEF6 RARB PRAMEF12	2.72e-04	55	209	5	GO:0042974
GeneOntologyMolecularFunction	N-acetylglucosamine-6-sulfatase activity	SULF2 SULF1	3.25e-04	3	209	2	GO:0008449
GeneOntologyMolecularFunction	MHC class Ib protein binding	KIR2DL3 KIR3DL1 KIR3DL2	5.72e-04	16	209	3	GO:0023029
Domain	-	PRAMEF5 LRG1 RXFP2 FBXO39 SLITRK6 NLRC3 CEP97 PRAMEF6 LRRIQ3 PRAMEF12 LINGO2 NLRP2 CMIP NISCH LGI3 LRRC27 SLIT3 FSHR	1.48e-08	321	203	18	3.80.10.10
Domain	L_dom-like	PRAMEF5 LRG1 RXFP2 FBXO39 SLITRK6 NLRC3 CEP97 PRAMEF6 LRRIQ3 PRAMEF12 LINGO2 NLRP2 CMIP NISCH LGI3 LRRC27 SLIT3 FSHR	2.07e-08	328	203	18	IPR032675
Domain	TF_fork_head_CS_2	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXF1 FOXC1 FOXE1 FOXS1	3.11e-08	46	203	8	IPR030456
Domain	TF_fork_head_CS_1	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXF1 FOXC1 FOXE1 FOXS1	3.71e-08	47	203	8	IPR018122
Domain	FH	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXF1 FOXC1 FOXE1 FOXS1	5.22e-08	49	203	8	SM00339
Domain	FORK_HEAD_1	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXF1 FOXC1 FOXE1 FOXS1	5.22e-08	49	203	8	PS00657
Domain	FORK_HEAD_2	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXF1 FOXC1 FOXE1 FOXS1	5.22e-08	49	203	8	PS00658
Domain	Fork_head_dom	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXF1 FOXC1 FOXE1 FOXS1	5.22e-08	49	203	8	IPR001766
Domain	FORK_HEAD_3	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXF1 FOXC1 FOXE1 FOXS1	5.22e-08	49	203	8	PS50039
Domain	Forkhead	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXF1 FOXC1 FOXE1 FOXS1	5.22e-08	49	203	8	PF00250
Domain	Leu-rich_rpt	LRG1 RXFP2 FBXO39 SLITRK6 NLRC3 CEP97 LRRIQ3 LINGO2 NLRP2 NISCH LGI3 LRRC27 SLIT3 FSHR	1.67e-06	271	203	14	IPR001611
Domain	ARM-type_fold	SMG1 SCYL1 USP9Y TEX10 TRRAP DOCK5 DNAAF5 AP2A1 TAF2 GCN1 TANGO6 ARFGEF1 HEATR1 AP3B2 VPS35	4.77e-06	339	203	15	IPR016024
Domain	HEAT_REPEAT	SMG1 SCYL1 TEX10 DNAAF5 GCN1 TANGO6 HEATR1	1.09e-05	70	203	7	PS50077
Domain	LRR	LRG1 RXFP2 FBXO39 SLITRK6 CEP97 LRRIQ3 LINGO2 NISCH LGI3 LRRC27 SLIT3	1.30e-05	201	203	11	PS51450
Domain	ARM-like	SMG1 SCYL1 USP9Y TEX10 TRRAP DNAAF5 AP2A1 GCN1 TANGO6 ARFGEF1 HEATR1 AP3B2	4.16e-05	270	203	12	IPR011989
Domain	ELFV_dehydrog_N	GLUD1 GLUD2	1.18e-04	2	203	2	PF02812
Domain	Glu/Leu/Phe/Val_DH_C	GLUD1 GLUD2	1.18e-04	2	203	2	IPR006096
Domain	Glu/Leu/Phe/Val_DH_dimer_dom	GLUD1 GLUD2	1.18e-04	2	203	2	IPR006097
Domain	Glu/Leu/Phe/Val_DH	GLUD1 GLUD2	1.18e-04	2	203	2	IPR006095
Domain	ELFV_dehydrog	GLUD1 GLUD2	1.18e-04	2	203	2	PF00208
Domain	NAD_bind_Glu_DH	GLUD1 GLUD2	1.18e-04	2	203	2	IPR033922
Domain	GLFV_DEHYDROGENASE	GLUD1 GLUD2	1.18e-04	2	203	2	PS00074
Domain	IFI44_fam	IFI44L IFI44	1.18e-04	2	203	2	IPR024644
Domain	Extracellular_sulfatase	SULF2 SULF1	1.18e-04	2	203	2	IPR014615
Domain	Extracellular_sulfatase_C	SULF2 SULF1	1.18e-04	2	203	2	IPR024609
Domain	DUF3740	SULF2 SULF1	1.18e-04	2	203	2	PF12548
Domain	ELFV_dehydrog	GLUD1 GLUD2	1.18e-04	2	203	2	SM00839
Domain	Glu/Leu/Phe/Val_DH_AS	GLUD1 GLUD2	1.18e-04	2	203	2	IPR033524
Domain	LRR_1	LRG1 RXFP2 SLITRK6 CEP97 LINGO2 NISCH LGI3 LRRC27 SLIT3 FSHR	1.46e-04	219	203	10	PF00560
Domain	-	SCYL1 TEX10 TRRAP DNAAF5 AP2A1 GCN1 TANGO6 ARFGEF1 HEATR1 AP3B2	1.64e-04	222	203	10	1.25.10.10
Domain	HEAT	SCYL1 TEX10 DNAAF5 GCN1 HEATR1	1.69e-04	48	203	5	PF02985
Domain	HEAT	SCYL1 TEX10 DNAAF5 GCN1 HEATR1	4.15e-04	58	203	5	IPR000357
Domain	-	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 METAP2 FOXF1 FOXC1 FOXE1 FOXS1	6.52e-04	218	203	9	1.10.10.10
Domain	HEAT_type_2	TEX10 DNAAF5 GCN1	7.69e-04	17	203	3	IPR021133
Domain	PRAME_family	PRAMEF5 PRAMEF6 PRAMEF12	1.08e-03	19	203	3	IPR026271
Domain	Protocadherin	PCDH11X PCDH11Y	1.15e-03	5	203	2	PF08374
Domain	Protocadherin	PCDH11X PCDH11Y	1.15e-03	5	203	2	IPR013585
Domain	WHTH_DNA-bd_dom	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 METAP2 FOXF1 FOXC1 FOXE1 FOXS1	1.36e-03	242	203	9	IPR011991
Domain	Dynamin_central	DNM1L MX1	1.71e-03	6	203	2	IPR000375
Domain	GED	DNM1L MX1	1.71e-03	6	203	2	SM00302
Domain	Dynamin_M	DNM1L MX1	1.71e-03	6	203	2	PF01031
Domain	GED_dom	DNM1L MX1	1.71e-03	6	203	2	IPR020850
Domain	FAT	SMG1 TRRAP	1.71e-03	6	203	2	PS51189
Domain	FATC	SMG1 TRRAP	1.71e-03	6	203	2	PS51190
Domain	GED	DNM1L MX1	1.71e-03	6	203	2	PS51388
Domain	Dynamin_GTPase_CS	DNM1L MX1	1.71e-03	6	203	2	IPR019762
Domain	FATC_dom	SMG1 TRRAP	1.71e-03	6	203	2	IPR003152
Domain	GED	DNM1L MX1	1.71e-03	6	203	2	PF02212
Domain	GED	DNM1L MX1	1.71e-03	6	203	2	IPR003130
Domain	PIK_FAT	SMG1 TRRAP	1.71e-03	6	203	2	IPR014009
Domain	FATC	SMG1 TRRAP	1.71e-03	6	203	2	SM01343
Pubmed	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXF1 FOXC1	8.14e-11	13	213	6	7957066
Pubmed	Six members of the mouse forkhead gene family are developmentally regulated.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXC1 FOXS1	2.35e-10	15	213	6	7689224
Pubmed	Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXC1 FOXS1	3.74e-10	16	213	6	10208738
Pubmed	FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines.	FOXD4L6 FOXD4L5 FOXD4L4 FOXC1	6.81e-09	5	213	4	12234674
Pubmed	Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	2.03e-08	6	213	4	27092474
Pubmed	Expression of the winged helix genes fkh-4 and fkh-5 defines domains in the central nervous system.	SCYL1 FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	3.40e-08	16	213	5	8861101
Pubmed	The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	9.39e-08	8	213	4	8530406
Pubmed	Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXF1	1.18e-07	20	213	5	12812790
Pubmed	An amphioxus winged helix/forkhead gene, AmphiFoxD: insights into vertebrate neural crest evolution.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	1.68e-07	9	213	4	12412011
Pubmed	Type II transmembrane serine protease gene variants associate with breast cancer.	HGF TMPRSS3 TMPRSS7	2.27e-07	3	213	3	25029565
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SMG1 GTPBP6 MYO1D SIPA1L3 PRPF6 TEX10 DCTN1 PTGFR PSMA8 AP2A1 PMPCA SYNE2 GLUD1 GLUD2 MLLT1 TMPRSS7 CAMSAP2 DNAH8 PCLO HEATR1 INSYN2A UTP18 SLC12A4 DGKK VPS35 MACF1 PCID2	2.70e-07	1442	213	27	35575683
Pubmed	Docking motif-guided mapping of the interactome of protein phosphatase-1.	MYO1D CNST ITPR3 PCDH11X KNL1 CEP192 HYDIN	6.37e-07	80	213	7	19389623
Pubmed	Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.	PRAMEF5 PRAMEF26 PRAMEF6 PRAMEF12 NLRP2	7.20e-07	28	213	5	25089626
Pubmed	Zscan5b Deficiency Impairs DNA Damage Response and Causes Chromosomal Aberrations during Mitosis.	ZSCAN5A ZSCAN5B ZSCAN5C	9.02e-07	4	213	3	31155506
Pubmed	ZSCAN5B and primate-specific paralogs bind RNA polymerase III genes and extra-TFIIIC (ETC) sites to modulate mitotic progression.	ZSCAN5A ZSCAN5B ZSCAN5C	9.02e-07	4	213	3	27732952
Pubmed	A genetic study of the suppressors of the Engrailed-1 cerebellar phenotype.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	9.36e-07	13	213	4	16884697
Pubmed	ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation.	PRAMEF5 PRAMEF6 ZSCAN5A PRAMEF12 ZSCAN5B ZSCAN5C	1.53e-06	58	213	6	31598710
Pubmed	Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	1.77e-06	15	213	4	22045912
Pubmed	Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.	KIR2DL3 KIR3DL1 KIR3DL2	2.24e-06	5	213	3	7716543
Pubmed	Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.	PRAMEF5 PRAMEF26 PRAMEF6 RARB PRAMEF12	2.30e-06	35	213	5	19389355
Pubmed	Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.	CNST PLEKHN1 ANKRD27 COMMD4 AP2A1 SULF1 SYNE2 AMOTL1 SLITRK6 ZC3H7B TRAF7 MAT2B CEP192 VPS35 RACGAP1 PNPLA8 YY1AP1	4.34e-06	750	213	17	11230166
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TET2 GTPBP6 CNST SIPA1L3 USP9Y DCTN1 AP2A1 SULF1 GLUD1 MAP3K11 STAMBPL1 METAP2 VWF RARB ADNP2 CACHD1 REV3L NISCH LGI3 MACF1 YY1AP1 ST18 SNTA1	4.66e-06	1285	213	23	35914814
Pubmed	Functional equivalency between Otx2 and Otx1 in development of the rostral head.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	4.93e-06	19	213	4	9895322
Pubmed	Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	7.54e-06	21	213	4	9449667
Pubmed	Identification of the mouse killer immunoglobulin-like receptor-like (Kirl) gene family mapping to chromosome X.	KIR2DL3 KIR3DL1 KIR3DL2	7.79e-06	7	213	3	12618911
Pubmed	Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis.	KIR2DL3 KIR3DL1 KIR3DL2	7.79e-06	7	213	3	26928464
Pubmed	Expression of a killer cell receptor-like gene in plastic regions of the central nervous system.	KIR2DL3 KIR3DL1 KIR3DL2	7.79e-06	7	213	3	15748957
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF5 PRAMEF26 PRAMEF6 PRAMEF12	9.18e-06	22	213	4	31729367
Pubmed	Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	9.18e-06	22	213	4	17389379
Pubmed	A population-based cohort study of KIR genes and genotypes in relation to cervical intraepithelial neoplasia.	KIR2DL3 KIR3DL1 KIR3DL2	1.24e-05	8	213	3	15730517
Pubmed	Human diversity in killer cell inhibitory receptor genes.	KIR2DL3 KIR3DL1 KIR3DL2	1.24e-05	8	213	3	9430221
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	USP45 PRAMEF5 SALL3 CNST SREBF2 DCTN1 RXFP2 DCAF17 HSD3B2 FERMT2 PRAMEF6 SHLD2 DNM1L PRAMEF12 CEP192 HEATR1 GRAMD2A TGIF1 MACF1 NCKAP1L	1.30e-05	1084	213	20	11544199
Pubmed	Otx2 is required to respond to signals from anterior neural ridge for forebrain specification.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	1.32e-05	24	213	4	11820816
Pubmed	A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	1.32e-05	24	213	4	29992973
Pubmed	MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.	PRAMEF5 PRAMEF26 PRAMEF6 PRAMEF12	1.56e-05	25	213	4	37451217
Pubmed	Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	1.84e-05	26	213	4	15857913
Pubmed	Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.	KIR2DL3 KIR3DL1 KIR3DL2	1.85e-05	9	213	3	7749980
Pubmed	Alternatively spliced forms of human killer inhibitory receptors.	KIR2DL3 KIR3DL1 KIR3DL2	1.85e-05	9	213	3	8662091
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MAZ PLEKHN1 TRRAP INO80D SULF2 FBXO5 MCM3AP MLLT1 TAF2 IQCM FOXC1 KNL1 TRAF7 NTPCR ADNP2 REV3L MTPAP MACF1 OSMR PCID2	1.97e-05	1116	213	20	31753913
Pubmed	Assessment of killer cell immunoglobulinlike receptor expression and corresponding HLA class I phenotypes demonstrates heterogenous KIR expression independent of anticipated HLA class I ligands.	KIR2DL3 KIR3DL1 KIR3DL2	2.63e-05	10	213	3	12559621
Pubmed	Distinctive KIR and HLA diversity in a panel of north Indian Hindus.	KIR2DL3 KIR3DL1 KIR3DL2	2.63e-05	10	213	3	11904677
Pubmed	Molecular profiling of synovial joints: use of microarray analysis to identify factors that direct the development of the knee and elbow.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	2.88e-05	29	213	4	22972626
Pubmed	Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.	PRAMEF5 PRAMEF6 PRAMEF12 NLRP2	3.31e-05	30	213	4	38786026
Pubmed	Sonic hedgehog regulation of Foxf2 promotes cranial neural crest mesenchyme proliferation and is disrupted in cleft lip morphogenesis.	FOXF1 FOXC1 FOXE1	3.60e-05	11	213	3	28506991
Pubmed	Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity.	SULF2 SULF1	3.73e-05	2	213	2	16901266
Pubmed	Glutamate Delta-1 Receptor Regulates Inhibitory Neurotransmission in the Nucleus Accumbens Core and Anxiety-Like Behaviors.	GLUD1 GLUD2	3.73e-05	2	213	2	34173171
Pubmed	Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulation.	GLUD1 GLUD2	3.73e-05	2	213	2	28621566
Pubmed	Decreased expression of killer cell inhibitory receptors on natural killer cells in eutopic endometrium in women with adenomyosis.	KIR2DL3 KIR3DL1	3.73e-05	2	213	2	15217996
Pubmed	Interferon-Induced Protein 44 and Interferon-Induced Protein 44-Like Restrict Replication of Respiratory Syncytial Virus.	IFI44L IFI44	3.73e-05	2	213	2	32611756
Pubmed	Scatter factor/hepatocyte growth factor is essential for liver development.	HGF VWF	3.73e-05	2	213	2	7854452
Pubmed	GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior.	GLUD1 GLUD2	3.73e-05	2	213	2	32078638
Pubmed	Structure-activity relationships within the N-terminal short consensus repeats (SCR) of human CR1 (C3b/C4b receptor, CD35): SCR 3 plays a critical role in inhibition of the classical and alternative pathways of complement activation.	C3 CR1	3.73e-05	2	213	2	10382758
Pubmed	Development of mice with brain-specific deletion of floxed glud1 (glutamate dehydrogenase 1) using cre recombinase driven by the nestin promoter.	GLUD1 GLUD2	3.73e-05	2	213	2	23595828
Pubmed	HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo.	SULF2 SULF1	3.73e-05	2	213	2	16192265
Pubmed	Epithelial Deletion of Sulf2 Exacerbates Bleomycin-Induced Lung Injury, Inflammation, and Mortality.	SULF2 SULF1	3.73e-05	2	213	2	28657777
Pubmed	Conservation of PCDHX in mammals; expression of human X/Y genes predominantly in brain.	PCDH11X PCDH11Y	3.73e-05	2	213	2	11003707
Pubmed	Involvement of TRPV2 and SOCE in calcium influx disorder in DMD primary human myotubes with a specific contribution of α1-syntrophin and PLC/PKC in SOCE regulation.	TRPV2 SNTA1	3.73e-05	2	213	2	23426965
Pubmed	Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways.	GLUD1 GLUD2	3.73e-05	2	213	2	21621574
Pubmed	SULF1/SULF2 splice variants differentially regulate pancreatic tumour growth progression.	SULF2 SULF1	3.73e-05	2	213	2	24726914
Pubmed	Pcdh11x Negatively Regulates Dendritic Branching.	PCDH11X PCDH11Y	3.73e-05	2	213	2	25687328
Pubmed	Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.	GLUD1 GLUD2	3.73e-05	2	213	2	28911206
Pubmed	Different NK cell surface phenotypes defined by the DX9 antibody are due to KIR3DL1 gene polymorphism.	KIR3DL1 KIR3DL2	3.73e-05	2	213	2	11207248
Pubmed	Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase.	GLUD1 GLUD2	3.73e-05	2	213	2	22875990
Pubmed	Molecular basis of human glutamate dehydrogenase regulation under changing energy demands.	GLUD1 GLUD2	3.73e-05	2	213	2	15578726
Pubmed	Important role of Ser443 in different thermal stability of human glutamate dehydrogenase isozymes.	GLUD1 GLUD2	3.73e-05	2	213	2	15044002
Pubmed	Differential involvement of the extracellular 6-O-endosulfatases Sulf1 and Sulf2 in brain development and neuronal and behavioural plasticity.	SULF2 SULF1	3.73e-05	2	213	2	20394677
Pubmed	Differential complement activation pathways promote C3b deposition on native and acetylated LDL thereby inducing lipoprotein binding to the complement receptor 1.	C3 CR1	3.73e-05	2	213	2	25349208
Pubmed	The pathophysiology and morphology of murine hydrocephalus in Hy-3 and Ch mutants.	FOXC1 HYDIN	3.73e-05	2	213	2	4784576
Pubmed	Induction of excitatory and inhibitory presynaptic differentiation by GluD1.	GLUD1 GLUD2	3.73e-05	2	213	2	22138648
Pubmed	SULFs in human neoplasia: implication as progression and prognosis factors.	SULF2 SULF1	3.73e-05	2	213	2	21599997
Pubmed	Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia.	GLUD1 GLUD2	3.73e-05	2	213	2	34220417
Pubmed	Sulf1A and HGF regulate satellite-cell growth.	HGF SULF1	3.73e-05	2	213	2	20442248
Pubmed	Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues.	GLUD1 GLUD2	3.73e-05	2	213	2	26241911
Pubmed	SREBP-2/PNPLA8 axis improves non-alcoholic fatty liver disease through activation of autophagy.	SREBF2 PNPLA8	3.73e-05	2	213	2	27767079
Pubmed	Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum.	GLUD1 GLUD2	3.73e-05	2	213	2	21446915
Pubmed	Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling.	SULF2 SULF1	3.73e-05	2	213	2	27294358
Pubmed	Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways.	SULF2 SULF1	3.73e-05	2	213	2	20479257
Pubmed	GluD1 binds GABA and controls inhibitory plasticity.	GLUD1 GLUD2	3.73e-05	2	213	2	38060673
Pubmed	Cadherin expression delineates the divisions of the postnatal and adult mouse amygdala.	PCDH11X PCDH11Y	3.73e-05	2	213	2	22592879
Pubmed	Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice.	GLUD1 GLUD2	3.73e-05	2	213	2	24593767
Pubmed	Potentiation of neuronal activity by tonic GluD1 current in brain slices.	GLUD1 GLUD2	3.73e-05	2	213	2	37154294
Pubmed	Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions.	SULF2 SULF1	3.73e-05	2	213	2	26448642
Pubmed	Protocadherin X ( PCDHX) and Y ( PCDHY) genes; multiple mRNA isoforms encoding variant signal peptides and cytoplasmic domains.	PCDH11X PCDH11Y	3.73e-05	2	213	2	14727141
Pubmed	Diffusion magnetic resonance tractography-based evaluation of commissural fiber abnormalities in a heparan sulfate endosulfatase-deficient mouse brain.	SULF2 SULF1	3.73e-05	2	213	2	35131262
Pubmed	Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission.	GLUD1 GLUD2	3.73e-05	2	213	2	22924626
Pubmed	Lack of association between protocadherin 11-X/Y (PCDH11X and PCDH11Y) polymorphisms and late onset Alzheimer's disease.	PCDH11X PCDH11Y	3.73e-05	2	213	2	21276771
Pubmed	Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function.	GLUD1 GLUD2	3.73e-05	2	213	2	11032875
Pubmed	Plasma Protein Biomarker Candidates for Myelodysplastic Syndrome Subgroups.	LRG1 AHSG	3.73e-05	2	213	2	26448929
Pubmed	Expression of Heparan Sulfate Endosulfatases in the Adult Mouse Brain: Co-expression of Sulf1 and Dopamine D1/D2 Receptors.	SULF2 SULF1	3.73e-05	2	213	2	34489650
Pubmed	Localization of Human Glutamate Dehydrogenases Provides Insights into Their Metabolic Role and Their Involvement in Disease Processes.	GLUD1 GLUD2	3.73e-05	2	213	2	29943084
Pubmed	KIR3DL1 and KIR3DL2 gene copy number variation in axial spondyloarthritis.	KIR3DL1 KIR3DL2	3.73e-05	2	213	2	25940819
Pubmed	Sulfs are regulators of growth factor signaling for satellite cell differentiation and muscle regeneration.	SULF2 SULF1	3.73e-05	2	213	2	17920055
Pubmed	Accelerated evolution of Protocadherin11X/Y: a candidate gene-pair for cerebral asymmetry and language.	PCDH11X PCDH11Y	3.73e-05	2	213	2	16874762
Pubmed	Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory.	GLUD1 GLUD2	3.73e-05	2	213	2	31898404
Pubmed	Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux.	GLUD1 GLUD2	3.73e-05	2	213	2	15378063
Pubmed	PCDH11 is X/Y homologous in Homo sapiens but not in Gorilla gorilla and Pan troglodytes.	PCDH11X PCDH11Y	3.73e-05	2	213	2	16825765
Pubmed	Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions.	GLUD1 GLUD2	3.73e-05	2	213	2	27422263
Pubmed	Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer.	KIR3DL1 KIR3DL2	3.73e-05	2	213	2	8777725
Pubmed	Aberrant epigenetic regulation of RARβ by TET2 is involved in cutaneous squamous cell carcinoma resistance to retinoic acid.	TET2 RARB	3.73e-05	2	213	2	35248720
Pubmed	Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans.	SULF2 SULF1	3.73e-05	2	213	2	12368295
Cytoband	9q21.11	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	1.12e-05	30	213	4	9q21.11
Cytoband	1p36.21	PRAMEF5 PRAMEF26 PRAMEF6 PRAMEF12	2.17e-04	63	213	4	1p36.21
Cytoband	1p31.1	PTGFR IFI44L LRRIQ3 IFI44	3.43e-04	71	213	4	1p31.1
GeneFamily	PRAME family	PRAMEF5 PRAMEF26 PRAMEF6 PRAMEF12	3.34e-05	24	141	4	686
GeneFamily	Non-clustered protocadherins	PCDH11X PCDH10 PCDH11Y	9.70e-05	12	141	3	21
GeneFamily	Forkhead boxes	FOXF1 FOXC1 FOXE1 FOXS1	3.45e-04	43	141	4	508
GeneFamily	CD molecules\|Killer cell immunoglobulin like receptors	KIR2DL3 KIR3DL1 KIR3DL2	3.48e-04	18	141	3	620
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	MYO1D CNST ITPR3 PCDH11X KNL1 CEP192 HYDIN	5.50e-04	181	141	7	694
GeneFamily	EF-hand domain containing\|Nucleotide excision repair\|Transcription and export complex 2	MCM3AP PCID2	5.95e-04	5	141	2	1276
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	CD109 C3	2.10e-03	9	141	2	1234
Coexpression	ROETH_TERT_TARGETS_UP	PLA2G4A IFI44L IFI44 MX1	3.69e-06	14	209	4	M18660
Coexpression	FOURATI_BLOOD_TWINRIX_AGE_25_83YO_RESPONDERS_VS_POOR_RESPONDERS_0DY_DN	HGF ATP8A2 CD109 RO60 USP9Y IFI44L KIR3DL1 PCLO IFI44 LINGO2 HEATR1 NBPF15 CMIP NISCH ERMAP SLC6A5 HBZ MX1 NCKAP1L	9.31e-06	746	209	19	M40863
ToppCell	COVID-19_Moderate-NK_activated\|World / disease group, cell group and cell class	CD300A TRANK1 SYNE2 IFI44L FBXO39 KIR2DL3 KIR3DL2 NLRC3 TRGC1 CLIC3 IFI44 DGKK MX1	6.36e-12	186	212	13	ff8f32f69516bf785224fa12f8139a95359b0279
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-NK_activated\|COVID-19_Severe / Disease, condition lineage and cell class	CD300A TRANK1 SYNE2 IFI44L KIR2DL3 KIR3DL2 TRGC1 CLIC3 IFI44 MACF1 MX1	3.49e-09	200	212	11	6a77f9643646bafc1157bf1fc1e4c614860ee642
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	USP9Y TRANK1 SYNE2 IFI44L KIR3DL1 TRGC1 IFI44 ARHGEF12 DGKK MACF1 MX1	3.49e-09	200	212	11	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HGF SULF1 PLA2G4A PCDH10 RARB REV3L SNCAIP SLIT3 OSMR SH3RF3	3.54e-08	195	212	10	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD300A TRANK1 SYNE2 IFI44L KIR2DL3 TRGC1 CLIC3 IFI44 MACF1 MX1	4.09e-08	198	212	10	0e918e9db9b884f5328d438e90efe065e27266ee
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD300A TRANK1 SYNE2 IFI44L KIR2DL3 TRGC1 CLIC3 IFI44 MACF1 MX1	4.09e-08	198	212	10	ce92d5fbc2eac27fb246b044fb1914ab92506275
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CD300A TRANK1 SYNE2 IFI44L KIR2DL3 TRGC1 CLIC3 IFI44 MACF1 MX1	4.09e-08	198	212	10	fed823d6e684d113bcc9ff3cd1803bb001aa02fa
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CD300A TRANK1 SYNE2 IFI44L KIR2DL3 TRGC1 CLIC3 IFI44 MACF1 MX1	4.09e-08	198	212	10	1ef3a6bd681c223eed58300348adfef89df5563c
ToppCell	COVID-19_Severe-Lymphoid_T/NK-NK_activated\|COVID-19_Severe / Disease group, lineage and cell class	CD300A TRANK1 SYNE2 IFI44L KIR2DL3 KIR3DL2 TRGC1 CLIC3 IFI44 MX1	4.29e-08	199	212	10	edf5f80b4c299e6bf462675f2cd3329d86c923d8
ToppCell	343B-Lymphocytic-NK_cells-Proliferating_NK_cell\|343B / Donor, Lineage, Cell class and subclass (all cells)	ZNF862 TEX10 RXFP2 KIR3DL1 ZNF367 KNL1 TANGO6 CHST10 RACGAP1	1.26e-07	169	212	9	02fa66a91b8bd2bf971aec4f5ec58318b5bfdf14
ToppCell	RSV-Healthy-1\|Healthy / Virus stimulation, Condition and Cluster	TREX1 DOCK5 IFI44L LRRIQ3 CLIC3 IFI44 IL18BP ERMAP MX1	1.69e-07	175	212	9	ff3a27f512a3a710ebc863b7b75cce8167d5440b
ToppCell	RSV-Healthy-1\|RSV / Virus stimulation, Condition and Cluster	TREX1 DOCK5 IFI44L LRRIQ3 CLIC3 IFI44 IL18BP ERMAP MX1	1.69e-07	175	212	9	ca52b99b03535a5b3a2751d6981708dc5b255b91
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 NLRC3 TRGC1 CLIC3 MACF1	3.10e-07	188	212	9	9abd78970bbe4ed03b59a83da63bbd334712f605
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 NLRC3 TRGC1 CLIC3 MACF1	3.10e-07	188	212	9	5ae8ccdd328cf117da1d01ced2c3b7f763a5f1f1
ToppCell	COVID-19-Heart-EC_3\|Heart / Disease (COVID-19 only), tissue and cell type	CD109 SULF2 IFI44L VWF IFI44 CACHD1 CMIP OSMR SH3RF3	3.39e-07	190	212	9	78e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HGF DOCK5 SULF1 PLA2G4A STAMBPL1 RARB ITGA8 SLIT3 SH3RF3	3.71e-07	192	212	9	4022f208eb5db760abd0aac782a25e8ab63efc64
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 LINGO2 DGKK	4.22e-07	195	212	9	98b02beafe1d418442e41f85cbf0c7b194fe5957
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 LINGO2 DGKK	4.22e-07	195	212	9	9ecae6c26a0d0607d101ccf1c38f0b23c5a256a8
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HGF SULF1 PLA2G4A RARB REV3L GXYLT2 SLIT3 OSMR SH3RF3	4.41e-07	196	212	9	2b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 LINGO2 DGKK	4.41e-07	196	212	9	9b3848dd4256cd6d9a21ef6bfdbd0cb7c0030005
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_NK-NK_CD16\|lymph-node_spleen / Manually curated celltypes from each tissue	CD300A DOCK5 SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 DGKK	4.41e-07	196	212	9	f7e5a7fad4547e8ab9ab8b140239281832fb4260
ToppCell	COVID-19_Severe-NK_activated\|World / disease group, cell group and cell class	CD300A SYNE2 IFI44L KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 MX1	4.60e-07	197	212	9	a60db36d1a192998e3ded63e0c7c08d41689f95f
ToppCell	COVID-19_Severe-NK_activated\|COVID-19_Severe / disease group, cell group and cell class	CD300A SYNE2 IFI44L KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 MX1	5.01e-07	199	212	9	bda28d975f4017ec5bded1d3c72310eabc5aac07
ToppCell	(17)_gd_T\|World / shred on Cell_type and subtype	CD109 DOCK5 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 CMIP OXNAD1	5.44e-07	201	212	9	7fcfe48758acf07cb3dda939ce589ae1518e41c9
ToppCell	343B-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ZNF862 RXFP2 PLA2G4A ZNF367 KNL1 CHST10 GSTZ1 RACGAP1	2.70e-06	182	212	8	b1e66ccd5f33b4801f1cafddf97f5fc0c6dba8d1
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-NK_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD300A GAPDHS KIR2DL3 KIR3DL1 NLRC3 TRGC1 CLIC3 DGKK	2.81e-06	183	212	8	b902390614fe924d48511e4187b36a0b49b08f23
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRANK1 PCDH11X PCDH10 ZAN PCLO DGKK ST18 HYDIN	2.92e-06	184	212	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRANK1 PCDH11X PCDH10 ZAN PCLO DGKK ST18 HYDIN	2.92e-06	184	212	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRANK1 PCDH11X PCDH10 ZAN PCLO DGKK ST18 HYDIN	2.92e-06	184	212	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO1D CARD10 SULF1 FOXC1 VWF SNCAIP DGKK OSMR	3.17e-06	186	212	8	ffbc78058be8f0dc2e0335cc4c3195a636d17721
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO1D CARD10 SULF1 FOXC1 VWF SNCAIP DGKK OSMR	3.17e-06	186	212	8	ed924852cd7132c8f6703522037dc22bd2c83193
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HGF CFAP251 SULF1 PLA2G4A REV3L SLIT3 OSMR SH3RF3	3.30e-06	187	212	8	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 MACF1	3.43e-06	188	212	8	f7dc29dfec68236883469e848be5db34f5526d6b
ToppCell	COVID-19_Moderate-NK_activated\|COVID-19_Moderate / disease group, cell group and cell class	CD300A IFI44L KIR2DL3 KIR3DL2 TRGC1 CLIC3 DGKK MX1	3.57e-06	189	212	8	8f9f1e71857bed6d59c4b087b6a6970f30fd86be
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO1D CARD10 SULF1 FOXC1 VWF SNCAIP DGKK OSMR	3.71e-06	190	212	8	3b9abc25b17e7295356ded57ff2ca519fa9f2686
ToppCell	Fetal_29-31_weeks-Immune-natural_killer_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CD300A KIR2DL3 KIR3DL1 KIR3DL2 NLRC3 TRGC1 CLIC3 LINGO2	3.86e-06	191	212	8	5696e2e2db7b898a1c7ab3582ae74cb712dd5bdf
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HGF DOCK5 SULF1 PLA2G4A STAMBPL1 RARB ITGA8 SH3RF3	3.86e-06	191	212	8	1caf726bd07fdca389e678fc16304a6ef1790423
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HGF DOCK5 SULF1 PLA2G4A STAMBPL1 RARB ITGA8 SH3RF3	3.86e-06	191	212	8	3d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HGF DOCK5 SULF1 PLA2G4A STAMBPL1 RARB ITGA8 SH3RF3	4.01e-06	192	212	8	9333aba0d04203ccccad78d82bf6359922f810a7
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD300A SYNE2 KIR2DL3 KIR3DL2 NLRC3 TRGC1 CLIC3 LINGO2	4.16e-06	193	212	8	54604c2c5dce2ff6f3ec7ca82b595b09b8cdafe8
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DOCK5 SYNE2 KIR2DL3 KIR3DL1 NLRC3 TRGC1 CLIC3 MACF1	4.33e-06	194	212	8	24837a27b0041fe8c348225fa8b09b127d743603
ToppCell	LV-10._Endothelium_II\|LV / Chamber and Cluster_Paper	INO80D SULF2 PCDH11X FOXC1 VWF PCDH11Y CMIP OSMR	4.33e-06	194	212	8	b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell	Fibroblasts-CD34+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	PTGFR C3 SLITRK6 ITGA8 CACHD1 GXYLT2 GUCY1A1 SLIT3	4.49e-06	195	212	8	c6b5249ac8714b1b701cde31d00ab53f28355c36
ToppCell	BAL-Severe-Lymphocyte-T/NK-NK_cell-NK\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 NLRC3 TRGC1 CLIC3 OXNAD1	4.84e-06	197	212	8	48311c7d85ffabf59fd1685c31c18b3e84a145b5
ToppCell	BAL-Severe-Lymphocyte-T/NK-NK_cell\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 NLRC3 TRGC1 CLIC3 OXNAD1	4.84e-06	197	212	8	92f35ea602489efd29ce3a8a186d1f70d65faf40
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 LINGO2	4.84e-06	197	212	8	bc37b8919f98dc18c2200834405f06823d965d78
ToppCell	Severe_COVID-19-T/NK-NK\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	TRANK1 SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 NLRC3 TRGC1 CLIC3	4.84e-06	197	212	8	cc20162892b59e48653981f91fc9a0c27064444d
ToppCell	BAL-Severe-Lymphocyte-T/NK-NK_cell-NK-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 NLRC3 TRGC1 CLIC3 OXNAD1	4.84e-06	197	212	8	a26dd66a6bd08b46657b3a7c41669e206a8887b3
ToppCell	mild-Lymphocytic-NK_cells\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 MACF1	5.03e-06	198	212	8	dce3c008757786aa6bd4a869456b76b4cbbb1d5b
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 MACF1	5.22e-06	199	212	8	4820f5bcd7bc34c2ebf6a3422cc8eb383a3b5a4e
ToppCell	COVID_vent-Lymphocytic-ILC-NK_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	CD300A SYNE2 KIR3DL1 TRGC1 CLIC3 ARHGEF12 DGKK MACF1	5.22e-06	199	212	8	5f914962e2572b0c6372465b81b7496fa663d93c
ToppCell	COVID_vent-Lymphocytic-ILC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	CD300A SYNE2 KIR3DL1 TRGC1 CLIC3 ARHGEF12 DGKK MACF1	5.22e-06	199	212	8	e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 MACF1	5.22e-06	199	212	8	eb05ccae5187e4701bbbe6d714a6d2808fbcf306
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 MACF1	5.22e-06	199	212	8	10c8729b779073c3bf808e85958d59147f0be5c5
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 MACF1	5.22e-06	199	212	8	867fd292f3879982422e840e087bfdb3b21a8715
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 MACF1	5.22e-06	199	212	8	5e9fe852a70546c9d235414a2c26ca3e67ba6eb9
ToppCell	Control-Lymphoid_T/NK-NK\|Control / Disease group, lineage and cell class	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 MACF1	5.22e-06	199	212	8	94b2693a8378b9b2c58c6aebb2c6658d75b2e3de
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 MACF1	5.22e-06	199	212	8	d2c9fb69e5ef75778a1652da293fcf8cfa7ecfcc
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 NLRC3 TRGC1 CLIC3	5.41e-06	200	212	8	0b65855617fb7730de48facf411e2a8980f9f780
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-NK-ILC\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 NLRC3 TRGC1 CLIC3	5.41e-06	200	212	8	4150170a135c37a7932bfb61acedac22dad01a3e
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Mild / Disease, condition lineage and cell class	USP9Y TRANK1 SYNE2 IFI44L STAMBPL1 IFI44 OXNAD1 MX1	5.41e-06	200	212	8	d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-NK\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 NLRC3 TRGC1 CLIC3	5.41e-06	200	212	8	d1cfc4ef6ae75c486427e393d98b84a2a7ec67fe
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-NK\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 NLRC3 TRGC1 CLIC3	5.41e-06	200	212	8	0a6fc7eff94e2f71af9f31a01779aafd2f4a6699
ToppCell	Caecum-T_cell-gd_T\|T_cell / Region, Cell class and subclass	CD109 DOCK5 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 CMIP	5.41e-06	200	212	8	564117144a3059017a07d66f718b9b5a1f18265b
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Severe / Disease, condition lineage and cell class	USP9Y TRANK1 SYNE2 IFI44L DYRK2 IFI44 OXNAD1 MX1	5.41e-06	200	212	8	deeed668b129e66156b5f6abe1a07a9bf842a14d
ToppCell	Control-Control-Lymphocyte-T/NK-NK\|Control / Disease, condition lineage and cell class	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3 MACF1	5.41e-06	200	212	8	c64c27dbf4df42ca2ad2bd94b50fab87b4050ef3
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 NLRC3 TRGC1 CLIC3	5.41e-06	200	212	8	b4d956067eb292cf2855c674d1eb05a5f2d988f7
ToppCell	mild-NK\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CD300A SYNE2 IFI44L KIR2DL3 KIR3DL1 CLIC3 MACF1 MX1	5.41e-06	200	212	8	a11fb1d7e124c352eb73fea0e0ec0fed577c97f7
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-NK-ILC\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CD300A SYNE2 KIR2DL3 KIR3DL1 KIR3DL2 NLRC3 TRGC1 CLIC3	5.41e-06	200	212	8	c09bb5c994f098d86e873bd3f1d911b02563e6e2
ToppCell	356C-Fibroblasts-Fibroblast-D\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CCDC168 CD209 FBXO39 KYNU LRRIQ3 VWF PCLO	1.14e-05	159	212	7	0a3a363b30a8c741e1a3e2525725108d03c21776
ToppCell	FLU-Healthy-1\|FLU / Virus stimulation, Condition and Cluster	SYNE2 IFI44L KIR3DL1 KNL1 CLIC3 IFI44 MX1	1.14e-05	159	212	7	fe2a9f79b058e89214256e736f6e266830cdfa28
ToppCell	356C-Fibroblasts-Fibroblast-D-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CCDC168 CD209 FBXO39 KYNU LRRIQ3 VWF PCLO	1.14e-05	159	212	7	299e2162a82e31196d7f3a110c2db622349edfff
ToppCell	FLU-Healthy-1\|Healthy / Virus stimulation, Condition and Cluster	SYNE2 IFI44L KIR3DL1 KNL1 CLIC3 IFI44 MX1	1.14e-05	159	212	7	97c8e16a7ac10ebba96daee97f9fb1d4a404f23b
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|356C / Donor, Lineage, Cell class and subclass (all cells)	PLEKHN1 INO80D SYNE2 NLRC3 CEP97 TANGO6 CHST10	1.50e-05	166	212	7	c4f7ea1cad962b1d6ad77423d15978b68a0d6f1d
ToppCell	facs-Aorta-Heart-3m-Endothelial-endocardial_endothelial_cells\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IP6K3 SULF1 CDADC1 ELMOD1 VWF GXYLT2 CMIP	1.56e-05	167	212	7	a4a795751644b22af616335379e64ae95175180c
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZNF597 SYCP2L CD109 MAP3K11 VWF LINGO2 OSMR	1.82e-05	171	212	7	1ae4b6a25bc9c1065cf5d95998ebcc70aee21ab5
ToppCell	Mild-CD4+_T_Exhausted\|World / Disease group and Cell class	CFAP251 IFI44L IFI44 NLRP2 NBPF15 MX1 NCKAP1L	1.89e-05	172	212	7	efe68d9477aa873b1637ee689f298120303aa322
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCDC168 FBXO5 FOXC1 KNL1 VWF GXYLT2 RACGAP1	2.11e-05	175	212	7	d43ae33a6256606ce848247cad32d74f21b38988
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD300A DOCK5 KIR2DL3 KIR3DL1 KIR3DL2 TRGC1 CLIC3	2.11e-05	175	212	7	8fb8c4b9e2d9b7d737f59cd9bd3dc2bca5a8dfc4
ToppCell	(03)_Secretory-(4)_1wkpi\|(03)_Secretory / shred by cell type and Timepoint	ITPR3 SULF2 FBXO5 SYNE2 GRAMD2A CMIP OSMR	2.11e-05	175	212	7	06b52f85baa31b55bb31477244892b6da79fe2c9
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	TRANK1 IFI44L FBXO39 IFI44 OSMR MX1	2.17e-05	118	212	6	f76fc6db7368a1e8e5e4f8535fc3dc78afe13b9b
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TRANK1 IFI44L FBXO39 IFI44 OSMR MX1	2.17e-05	118	212	6	c5c6724e0e526d7c2fc8cabff4a112a900ec997f
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRANK1 IFI44L FBXO39 IFI44 OSMR MX1	2.17e-05	118	212	6	0dcac16eea8e7978de370a815da9a0cdd212598e
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRANK1 IFI44L FBXO39 IFI44 OSMR MX1	2.17e-05	118	212	6	7da3957d102e9f9825fc2609d6d0bd9ca6a3fba4
ToppCell	Control-Lymphoid_T/NK-CD4+_T_activated\|Control / Disease group, lineage and cell class	TRANK1 IFI44L FBXO39 IFI44 OSMR MX1	2.27e-05	119	212	6	d7352d0dafbb664619b7a1e3cd07b159fdfec197
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SULF1 PLA2G4A FOXC1 IFI44 CMIP SNCAIP OSMR	2.27e-05	177	212	7	d68132e145bd413404fdbe215b5dbe520e756e50
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_C\|356C / Donor, Lineage, Cell class and subclass (all cells)	CD300A SYNE2 KIR2DL3 KIR3DL1 NLRC3 TRGC1 CLIC3	2.36e-05	178	212	7	7203149864cc8d5ae25329fdbf15c6b73c3d3595
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HGF SULF1 PLA2G4A STAMBPL1 RARB ITGA8 SH3RF3	2.53e-05	180	212	7	280ff5c8f292be1b88120db5ff1788b750644856
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANKRD27 DOCK5 FBXO5 MLLT1 TRAF7 NTPCR ERMAP	2.53e-05	180	212	7	1bc01bb76d0d3f8db74f9244436d3e6d6015ed5d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HGF SULF1 PLA2G4A STAMBPL1 RARB ITGA8 SH3RF3	2.53e-05	180	212	7	fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANKRD27 DOCK5 FBXO5 MLLT1 TRAF7 NTPCR ERMAP	2.53e-05	180	212	7	2a28fbfe10a340c8662c2c8be33792f41fc09088
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SYCP2L CD109 SULF2 SYNE2 ITGA8 MACF1 SH3RF3	2.53e-05	180	212	7	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANKRD27 DOCK5 FBXO5 MLLT1 TRAF7 NTPCR ERMAP	2.53e-05	180	212	7	12f3c4c4aa7fe03c0ef847bd4d4942c808015f5f
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FBXO5 SULF1 PLA2G4A SLITRK6 FOXF1 RARB ITGA8	2.62e-05	181	212	7	9b2d207dc9fc2228a1555ed360286bb7c2d988ff
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARD10 LRG1 FBXO5 SYNE2 C3 KNL1 RACGAP1	2.62e-05	181	212	7	566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARD10 LRG1 FBXO5 SYNE2 C3 KNL1 RACGAP1	2.62e-05	181	212	7	db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	TRANK1 SYNE2 IFI44L GCN1 IFI44 NBPF15 MX1	2.72e-05	182	212	7	1aea96ee211f7b9caef7fd385233f51be6021a73
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TRANK1 SYNE2 IFI44L GCN1 IFI44 NBPF15 MX1	2.72e-05	182	212	7	b427e43ee523a3ea9eca3207f3d82042f10f022a
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRANK1 SYNE2 IFI44L GCN1 IFI44 NBPF15 MX1	2.72e-05	182	212	7	c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRANK1 SYNE2 IFI44L GCN1 IFI44 NBPF15 MX1	2.72e-05	182	212	7	4cb182ef39be2044a6ad7266f332d4177591e550
Drug	methoxyethylmercury	GLUD1 GLUD2 KIR3DL1	7.19e-07	3	205	3	CID000115155
Disease	fascioliasis (biomarker_via_orthology)	GLUD1 GLUD2	1.28e-04	3	194	2	DOID:885 (biomarker_via_orthology)
Disease	Influenza	TREX1 IFI44L IFI44 MX1	3.83e-04	52	194	4	C0021400
Disease	Hypospadias	HSD3B2 DGKK	4.24e-04	5	194	2	C0848558
Disease	response to peginterferon alfa-2a	ZNF367 VWF CENPO	5.78e-04	25	194	3	EFO_0010103
Disease	childhood absence epilepsy (biomarker_via_orthology)	GLUD1 GLUD2	6.34e-04	6	194	2	DOID:1825 (biomarker_via_orthology)
Disease	mesangial proliferative glomerulonephritis (biomarker_via_orthology)	VWF ITGA8	1.17e-03	8	194	2	DOID:4783 (biomarker_via_orthology)
Disease	sarcoma (is_implicated_in)	SREBF2 KNL1	1.17e-03	8	194	2	DOID:1115 (is_implicated_in)
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CACNA1S SLC6A5 SNTA1	1.70e-03	36	194	3	DOID:11723 (implicated_via_orthology)
Disease	oppositional defiant disorder measurement	MLLT1 RARB ST18	1.70e-03	36	194	3	EFO_0007679
Disease	Primary ciliary dyskinesia	DNAAF5 RSPH4A HYDIN	1.70e-03	36	194	3	cv:C0008780
Disease	Cryptorchidism	RXFP2 HSD3B2	1.87e-03	10	194	2	C0010417
Disease	myelodysplastic syndrome	PLA2G4A TAF2	1.87e-03	10	194	2	EFO_0000198
Disease	response to selective serotonin reuptake inhibitor	TBC1D1 KYNU NTPCR OSMR	2.12e-03	82	194	4	EFO_0005658
Disease	primary angle closure glaucoma	FERMT2 ST18	2.27e-03	11	194	2	EFO_1001506
Disease	Paranoia	HSD3B2 DNAH8	2.27e-03	11	194	2	C1456784
Disease	Colorectal Carcinoma	TET2 SALL3 CD109 MCM3AP PCDH11X CAMSAP2 DNAH8 RARB ZSCAN5A ARFGEF1 PTPRT ZKSCAN3	2.48e-03	702	194	12	C0009402
Disease	epilepsy	PLA2G4A CAMSAP2 IQCM	2.48e-03	41	194	3	EFO_0000474
Disease	venous thromboembolism, response to antineoplastic agent	CAMSAP2 IQCM LRRIQ3	2.48e-03	41	194	3	EFO_0004286, GO_0097327
Disease	clostridium difficile infection	ANKRD27 SLC25A33 PTPRT RACGAP1 PCID2	2.69e-03	144	194	5	EFO_0009130
Disease	PARKINSON DISEASE, LATE-ONSET	GLUD2 SNCAIP	2.72e-03	12	194	2	C3160718
Disease	visual epilepsy (biomarker_via_orthology)	SREBF2 GLUD1 GLUD2 GABBR1	2.98e-03	90	194	4	DOID:11832 (biomarker_via_orthology)
Disease	Alcohol Use Disorder	VWF ST18 GABBR1	3.04e-03	44	194	3	C0001956
Disease	taurolithocholate 3-sulfate measurement	PLA2G4A RARB	3.20e-03	13	194	2	EFO_0021036
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	SULF2 PMPCA SYNE2 AHSG CMIP SLC12A4 MACF1	3.25e-03	291	194	7	EFO_0008317, EFO_0020946
Disease	Seizures	TREX1 ZNF142 SLC30A1 TRRAP TBCK MACF1	3.29e-03	218	194	6	C0036572
Disease	Thrombus	HGF VWF GUCY1A1	3.45e-03	46	194	3	C0087086
Disease	Gastrointestinal Stromal Sarcoma	SALL3 FOXF1 DYRK2	3.67e-03	47	194	3	C3179349
Disease	Primary Ciliary Dyskinesia	DNAAF5 RSPH4A HYDIN	3.67e-03	47	194	3	C4551720
Disease	periodontitis	PSMA8 TBC1D1 MCM3AP ITGA8 PTPRT TGIF1	3.68e-03	223	194	6	EFO_0000649
Disease	motion sickness	LINGO2 GXYLT2 ST18	3.89e-03	48	194	3	EFO_0006928
Disease	Thrombosis	HGF VWF GUCY1A1	4.13e-03	49	194	3	C0040053
Disease	Proteinuria	VWF RARB	4.27e-03	15	194	2	HP_0000093
Disease	hepatic encephalopathy (biomarker_via_orthology)	GLUD1 GLUD2	4.27e-03	15	194	2	DOID:13413 (biomarker_via_orthology)
Disease	Gastrointestinal Stromal Tumors	SALL3 FOXF1 DYRK2	4.37e-03	50	194	3	C0238198
Disease	testosterone measurement	TET2 HGF DOCK5 COMMD4 SYNE2 RXFP2 FOXC1 KNL1 ZAN LINGO2 GSS CMIP NISCH DGKK MACF1 YY1AP1 GREB1	4.64e-03	1275	194	17	EFO_0004908
Disease	brain ischemia (biomarker_via_orthology)	GLUD1 GLUD2 PLA2G4A C3	4.66e-03	102	194	4	DOID:2316 (biomarker_via_orthology)
Disease	–	CD209 KIR3DL1	4.86e-03	16	194	2	609423
Disease	Susceptibility to HIV infection	CD209 KIR3DL1	4.86e-03	16	194	2	cv:C1836230
Disease	systemic scleroderma (is_marker_for)	HGF C3 VWF	5.15e-03	53	194	3	DOID:418 (is_marker_for)
Disease	susceptibility to common cold measurement	ANKRD27 DOCK5 RARB	5.43e-03	54	194	3	EFO_0008417
Disease	essential hypertension, age at diagnosis	RXFP2 FOXC1 GUCY1A1	6.01e-03	56	194	3	EFO_0004918, MONDO_0001134

Protein segments in the cluster

Peptide	Gene	Start	Entry
HFKVASPLETCLLEL	nan	171	A8MVM7
LVLHIEQKPNRVFSC	DCAF17	486	Q5H9S7
RTIICTIHQPSAKLF	ABCG4	251	Q9H172
PFLKRACQDVSVVIH	HSD3B2	66	P26439
QLLEVQEKCLPSSRH	CARD10	771	Q9BWT7
QQVLSDSLHPKCRDI	ELMOD1	196	Q8N336
VTLSPKDCQVFRSDH	LRG1	36	P02750
PHCATIIARKSDLRV	CTCFL	431	Q8NI51
PQVSDTLLDCRKHLT	DCTN1	821	Q14203
RFPKLHDAIVEVVTC	DNM1L	456	O00429
LADCSLLPKLHIVDT	CLIC3	171	O95833
CTLDIFKTTIPHALL	ARFGEF1	1526	Q9Y6D6
LSATLHACPEVLLKD	FAM220BP	186	B1ANY3
LKHINPSQDELTVRC	ADGRG2	556	Q8IZP9
QVCVIRHPRTFLSKI	CMIP	61	Q8IY22
SKEPVSRHLCELLAQ	AP2A1	961	O95782
CLHFKQLATLESPTI	CACHD1	641	Q5VU97
KVRVELLHNPAFCSL	C3	861	P01024
SIREKVVEDPLCNFH	AMOTL1	61	Q8IY63
ELTQLKAAVERLCHP	CD209	241	Q9NNX6
KSNSRAHVCVLLQPL	CDADC1	181	Q9BWV3
LNLSEDHVCTIAKVP	CTBS	261	Q01459
CFIHREALVSKEISP	FAM200A	241	Q8TCP9
LTLLAVCHTVVPEKD	ATP8A2	501	Q9NTI2
IAVHLVRCRSAPKDS	ADNP2	931	Q6IQ32
CFQSIELLKSRPAHL	ARHGEF12	371	Q9NZN5
LPDTCRSDHIVVQKV	AP3B2	1001	Q13367
RKVSEHICLSELPFV	CFAP251	976	Q8TBY9
SVLHTEACQRLKASP	C17orf113	186	A0A1B0GUU1
SELPLECATHFVRIK	OSMR	101	Q99650
IRKAHQETFPSLCQL	RARB	191	P10826
RICFPKELSKSEHLQ	IQCM	86	A0A1B0GVH7
CQRIVPHTEVVDLKA	INSYN2A	346	Q6ZSG2
PGICQFLTEETKHRL	ITPR3	2141	Q14573
LDHCVFIQRKISRPS	KIR3DL2	401	P43630
ESFSILCIAHPLEKR	ANKRD27	106	Q96NW4
HSFCVITPQRKITLA	DGKK	276	Q5KSL6
AQFEHTILLRPTCKE	METAP2	456	P50579
PTHVKDVATVCRQLA	MAT2B	221	Q9NZL9
PLTFRDLNTHEKLCA	NLRC3	176	Q7RTR2
CREVKEAPNIVTLHV	GREB1	801	Q4ZG55
HPEAELQKCSVLSTL	GTPBP6	386	O43824
LNHCVFTQRKITRPS	KIR2DL3	306	P43628
DVSILPQLEHCSSRK	GABBR1	751	Q9UBS5
IRHNLSLNDCFVKIP	FOXD4L4	156	Q8WXT5
IRHNLSLNDCFVKIP	FOXD4L3	156	Q6VB84
IDSHLRDKLPNISCI	GABRQ	311	Q9UN88
CKALVLEQLTPALHS	IL18BP	131	O95998
CISLLLDPQRKQSHI	KIF12	296	Q96FN5
FITSPSLKDRIHCVA	IFI44L	306	Q53G44
KIFTHRPIEDLCANS	MFI	86	Q8NCR3
RKDITQQHLCDPLTV	MCM3AP	731	O60318
DPLTVSLIEKCTRFH	MCM3AP	741	O60318
CDVQVHKTRPLLNIR	BMI1	56	P35226
LDHCVFTQRKITRPS	KIR3DL1	401	P43629
IERCIGVTKPIFHST	PTGFR	131	P43088
LCNTTELLLHVPEKA	PCLO	591	Q9Y6V0
DRTKAFSTCIPHILV	OR14C36	231	Q8NHC7
RQSKHPALLCVVIFV	OR2T4	51	Q8NH00
IPTLLSLFKHECSRV	DNAH8	2681	Q96JB1
RSRKNLHVVLCFSPV	DNAH8	2941	Q96JB1
VLNCHLAVKVLSPED	NUS1	181	Q96E22
DLLPTFRHTLQKLTC	FBXO39	331	Q8N4B4
KFLETVHTLCGRIPQ	GXYLT2	401	A0PJZ3
RNLSEQLLPKHCATT	NCKAP1L	621	P55160
VRQVHSTERPFKCEK	MAZ	356	P56270
RSHTTALECKTLLPN	KNL1	1156	Q8NG31
KCNLTAVPTEALSHL	LINGO2	186	Q7L985
KENRNHLLPDIVTCV	NTPCR	171	Q9BSD7
SHVTLRLLKPECVLD	GCN1	921	Q92616
DTCHLQRVVFKNISP	NLRP2	726	Q9NX02
VSRELTHLCLAKNPI	NLRP2	866	Q9NX02
DHPVISCAKTKQLRV	HGF	481	P14210
LASRTPKDQSLCHVL	MPND	446	Q8N594
TAVVRCRQAPHLKAA	PCDH11X	831	Q9BZA7
KQSPSCVLHLEVFLE	PCDH10	86	Q9P2E7
NAVPAHCKVLVRVLD	PCDH10	336	Q9P2E7
RTVLIHCPEKISENK	MTPAP	76	Q9NVV4
EHTVCKPLVSREQRF	IP6K3	36	Q96PC2
VEFHRQSPAKILNCT	ITGA8	911	P53708
RCIVHQESGFKLLPV	MACF1	1721	Q9UPN3
LLPTLKENDTHCIDF	PTPRT	91	O14522
LVNEFPEKIACSLHV	OXNAD1	231	Q96HP4
HVSACIPLDRKEQFV	PRAMEF12	241	O95522
HLCKPLIRAIDSSNL	PCID2	186	Q5JVF3
ILRVDPVNFKLLSHC	HBZ	91	P02008
VELLEHCPSQVTVKA	CD109	46	Q6YHK3
VPTDTHECKRFILTI	IL31	126	Q6EBC2
HTLTCVTEREKFIVP	HYDIN	176	Q4G0P3
DSPSLKDRIHCVAFV	IFI44	296	Q8TCB0
LTEQLKPLHERLSSC	DOCK5	1611	Q9H7D0
PLAKCTSRTHDALIV	CR1	1961	P17927
IFSPTNKIRVLCHRI	CACNA1S	781	Q13698
LLPVLHFEKVVCSTL	FBXO5	191	Q9UKT4
PVARCSVRQLKEHAV	AHSG	96	P02765
IRHNLSLNECFVKVP	FOXC1	126	Q12948
RDSKLHIACFPVQLD	CEP97	796	Q8IW35
LRIIKPCNHVLSLSF	GLUD1	106	P00367
EEKQSPLQKHLRVCS	COMMD4	111	Q9H0A8
KRLLVLEAFQVSHPC	GSTZ1	191	O43708
HTCLPARKAVEATQV	MBTPS2	356	O43462
SNCEIRIHPKEDIFI	CEP192	1826	Q8TEP8
IRHNLSLNECFVKVP	FOXS1	66	O43638
CIRHVLEDKTAPFKQ	INO80D	36	Q53TQ3
SPHFSCISRLQRLVK	INO80D	291	Q53TQ3
EQRASHETLFCTKPL	CENPO	266	Q9BU64
VTKHLIPCIAQFSVA	HEATR1	2041	Q9H583
LVAAKICESILSLPH	CCDC168	3621	Q8NDH2
HLRCEKLTFNNPTTE	MLLT1	116	Q03111
NLSKILPALCHDITD	DNAAF5	356	Q86Y56
SELHPICNKSILRQE	FSHR	286	P23945
ICKTFNIRHPEELSL	FERMT2	126	Q96AC1
LERSHAAKCPDIATQ	GSS	286	P48637
DLLRRVCTHLQPSSK	GRAMD2A	171	Q8IUY3
TNCLAPLAKVIHERF	GAPDHS	226	O14556
IKTPSHIFCTRRAIN	SDIM1	46	Q6ZPB5
FLEHQRSCTKLPPVL	SALL3	66	Q9BXA9
SLPLVRKFAHSILQC	DYRK2	321	Q92630
SSVIRQLKVFPRHLC	PKD1L1	2376	Q8TDX9
VLLESDLKHLSQCPS	PRAMEF26	211	H0Y7S4
LNIDSHSDLKSCVPL	CAMSAP2	501	Q08AD1
LRIIKPCNHVLSLSF	GLUD2	106	P49448
CEALVPVIHRDLKSN	MAP3K11	231	Q16584
FERLTKICATHQDPL	CNST	261	Q6PJW8
LVKRLPFCQSNIISH	OR52N5	171	Q8NH56
FITAVVRCRQAPHLK	PCDH11Y	861	Q9BZA8
EKDCPTIIHFVLANI	PLA2G4A	631	P47712
PKLCITRVEELTFHL	PNPLA8	376	Q9NP80
TAHPKLILSEDQRCV	ERMAP	246	Q96PL5
VRHNLSLNECFIKLP	FOXF1	96	Q12946
LKQLTDTHPIQRCRF	RSPH4A	341	Q5TD94
LHRFCPTENVAKINR	PMPCA	221	Q10713
KEAVRLVHLPSCTVF	UTP18	496	Q9Y5J1
SAVCASRVKLQHLPA	PLEKHN1	221	Q494U1
QLDLHSCPKTIVFII	SNTA1	476	Q13424
KVLSPSGLLIHCQER	SLITRK6	336	Q9H5Y7
TVPEKSLDKEHRCIV	TRGC1	76	P0CF51
EHSKPVVLSLETLRC	SYNE2	5301	Q8WXH0
EDFCRHKVLPQLLTA	SCYL1	306	Q96KG9
LLLDSCVISDHPKIQ	SLC6A5	326	Q9Y345
IRHNLTLNDCFLKIP	FOXE1	101	O00358
VTTLKALNLRHCPLE	LRRC27	136	Q9C0I9
GCRLTQHLVQKLSPE	NBPF15	151	Q8N660
LLQRAVAHCPKAEVL	PRPF6	596	O94906
RDVHNLCPKEVLTFI	TAF2	761	Q6P1X5
AIKPIDRKSVHQICS	PMS2P2	76	O95744
IRHNLSLNDCFVKIP	FOXD4L5	156	Q5VV16
IRHNLSLNDCFVKIP	FOXD4L6	156	Q3SYB3
TNKHFPCLTVSVELL	HUS1	106	O60921
PLFSEALRSCKQHDV	SMG1	1376	Q96Q15
HCLRLALNTPKVTEQ	SIPA1L3	596	O60292
HSLLAVSAEPCVLKI	SHLD2	786	Q86V20
CITTLRPGIFKDLHQ	RXFP2	196	Q8WXD0
VEKTTPDCQLRAFHL	SNCAIP	271	Q9Y6H5
AFKAVSEVCRIPTHL	RO60	111	P10155
VPLLSKVDDIHAICS	RACGAP1	406	Q9H0H5
LQSCLLVIFATKPHV	PYCR3	66	Q53H96
RCTTAAHLALLVPKN	SLC12A4	816	Q9UP95
AIFTCPLEVIKTRLQ	SLC25A33	26	Q9BSK2
EKAHVTSNICQPREI	SLC36A3	166	Q495N2
CPDQAHRTSLVKQIE	ST18	461	O60284
PCVKSIVRQVLHGLD	SRPK3	186	Q9UPE1
SLSVQCPYEKEHRTL	CD300A	31	Q9UGN4
CRSHVRIAEAATLKP	CHST6	246	Q9GZX3
VCRDDALKNLSHTPV	CHST10	91	O43529
VDCSNQKLVRIPSHL	SLIT3	516	O75094
VICHTTVTALKDVPF	TGIF1	301	Q15583
AVPLISNKICNHRDV	TMPRSS3	361	P57727
LLESDLKHLSQCPSI	PRAMEF6	306	Q5VXH4
QVRIPKDFTCNLHVL	nan	31	Q6ZQY7
FKSSRTEPHCIIINL	USP45	106	Q70EL2
HCDVLAVPVKVTDRF	ZCCHC3	276	Q9NUD5
QLLKSTSVFARCHPL	VWF	226	P04275
SLCFHSTPIIQRKLL	REV3L	2196	O60673
VHIQLQCSSRLSDKP	TMPRSS7	456	Q7RTY8
LERLDTTAKVLPCQH	SH3RF3	61	Q8TEJ3
HEPLRTQCALAASKL	VPS35	646	Q96QK1
TKEPRLFSICKHVLV	STAMBPL1	411	Q96FJ0
LKTFNCILHAVPREE	SYCP2L	186	Q5T4T6
SDPIQALRKLTELCH	ZSCAN5B	56	A6NJL1
VTESPLVKAIFHACR	SREBF2	911	Q12772
SSIFECKPQRVHKLI	TBC1D1	91	Q86TI0
PELCLVLKVRHSENT	NISCH	776	Q9Y2I1
LLESDLKHLSQCPSI	PRAMEF5	306	Q5TYX0
ENSVLEIIAFHCKSP	TRPV2	351	Q9Y5S1
SDPIQALRKLTELCH	ZSCAN5A	56	Q9BUG6
DLQHPQDRVVTCKLF	TLE7	201	A0A1W2PR48
KVNTIRAHDNPVCTL	TRAF7	471	Q6Q0C0
LDKAVPSLHSLCQFR	TANGO6	526	Q9C0B7
KLLDHTCVVSETLLP	TEX10	781	Q9NXF1
TFIIDLLLHCPSKTV	USP9Y	1316	O00507
RTQKLQFLTVPHSCV	TNXA	296	Q16473
KTITHPRLCQYVDIS	TBCK	46	Q8TEA7
PSIVISEANKQHVRC	ZCCHC10	31	Q8TBK6
REQATVFKRICAPLH	nan	106	Q6ZVL8
RLCVNTVEIKEDTPH	ZNF862	526	O60290
CKEVHQTLILDPAQR	YY1AP1	151	Q9H869
VIRTCEKRPTFNQHT	ZNF790	141	Q6PG37
KISCHLREDIAQIPT	ZKSCAN3	276	Q9BRR0
LVHRDLKCENVLLSP	TSSK6	131	Q9BXA6
FSDLTKSLQECRIPH	UBXN10	251	Q96LJ8
EECVTLHPAQRSLSK	ZNF597	26	Q96LX8
CPFITRREKALNLHS	ZNF142	841	P52746
IFCHDSPKRVLVSVI	ZNF367	21	Q7RTV3
ICNRVFPREKSLQAH	ZNF367	171	Q7RTV3
RIIATAHIKCEDPTS	SLC30A1	381	Q9Y6M5
QESQERPVVTCLKHE	TRANK1	461	O15050
RVECQSHKLTVEDPV	PSMA8	96	Q8TAA3
SDLIPTIKFRHCSLL	GINS1	56	Q14691
TVNLEEPFHITCKIT	TRAPPC13	316	A5PLN9
ILIECAKRELHATTP	TET2	1871	Q6N021
TVRVTHKCFILPNDS	SULF1	611	Q8IWU6
FSQPKVTELCLLAVH	TREX1	26	Q9NSU2
LLSNCPAETAHLRKE	TRRAP	316	Q9Y4A5
KHILTTELRNQFIPC	TRRAP	336	Q9Y4A5
SDPIQALRKLTELCH	ZSCAN5C	56	A6NGD5
PIKVTHRCYILENDT	SULF2	596	Q8IWU5
SDQVALPRELLCKLH	ZC3H7B	71	Q9UGR2
NHSIPDACTLVLVKV	ZAN	1946	Q9Y493
LHTLAESICKLIFPE	GUCY1A1	71	Q02108
DTVQRIAAELKCHPT	KYNU	11	Q16719
HKVQDLPLREFDCIT	LGI3	206	Q8N145
FITDIHPLQSCIKLI	LRRIQ3	61	A6PVS8
PCLAEKLTSELITHI	MX1	321	P20591
DLIVCLFSKQPTHES	MYO1D	926	O94832