Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	5-methylcytosine dioxygenase activity	TET2 TET1	8.19e-05	3	105	2	GO:0070579
GeneOntologyMolecularFunction	histone H2AX kinase activity	VRK1 ATR	2.71e-04	5	105	2	GO:0141003
GeneOntologyMolecularFunction	histone kinase activity	VRK1 ATR DYRK1A	4.21e-04	28	105	3	GO:0035173
GeneOntologyCellularComponent	centriole	RTTN CEP76 CEP350 LRRCC1 SASS6 PCNT	2.22e-04	172	104	6	GO:0005814
GeneOntologyCellularComponent	non-motile cilium	MAP1A MAP1B PKD1L1 MYRIP MLF1 USH2A	4.46e-04	196	104	6	GO:0097730
GeneOntologyCellularComponent	nuclear RNA export factor complex	NXF5 NXF2	5.07e-04	7	104	2	GO:0042272
HumanPheno	Syndactyly	RTTN MAP3K20 DYRK1A FBXO11 PALB2 KIF7 SYNGAP1 JUP BRCA2 ARHGAP31 NPAP1 NECTIN4 CPLANE1 RAI1	3.76e-05	417	51	14	HP:0001159
HumanPheno	Gray matter heterotopias	DHX16 MAP1B RTTN CPLANE1 ZNF292	5.30e-05	42	51	5	HP:0002281
HumanPheno	Periventricular heterotopia	DHX16 MAP1B RTTN CPLANE1 ZNF292	5.30e-05	42	51	5	HP:0007165
HumanPheno	Cutaneous syndactyly	RTTN MAP3K20 DYRK1A KIF7 JUP NECTIN4 CPLANE1	6.28e-05	103	51	7	HP:0012725
MousePheno	embryonic growth retardation	PKD1L1 RTTN NACA MAP3K20 DYRK1A CHM GREB1L JUP PTPRJ BRCA2 PIK3C2A ANLN JAG1 TET1 SASS6 CPLANE1 PCNT	3.24e-06	763	86	17	MP:0003984
MousePheno	prenatal growth retardation	PKD1L1 RTTN NACA MAP3K20 DYRK1A CHM GREB1L JUP PTPRJ BRCA2 PIK3C2A ANLN JAG1 TET1 SASS6 CPLANE1 PCNT NPAT	4.43e-06	869	86	18	MP:0010865
MousePheno	decreased splenocyte apoptosis	NCOA3 BCL2L11 MLF1	1.23e-05	8	86	3	MP:0009341
MousePheno	prenatal lethality, incomplete penetrance	ATR BCL2L11 PATZ1 NACA DYRK1A CHM PALB2 JUP PTPRJ BRCA2 SH3RF2 TET1 MTMR2 CPLANE1 RAI1	4.50e-05	747	86	15	MP:0011101
MousePheno	abnormal prenatal growth/weight/body size	NCOA3 PATZ1 PKD1L1 RTTN NACA MAP3K20 DYRK1A CHM PALB2 GREB1L JUP PTPRJ BRCA2 PIK3C2A ARHGAP31 ANLN JAG1 TET1 SASS6 CPLANE1 PCNT NPAT	7.31e-05	1493	86	22	MP:0004196
MousePheno	abnormal embryonic growth/weight/body size	NCOA3 PKD1L1 RTTN NACA MAP3K20 DYRK1A CHM PALB2 GREB1L JUP PTPRJ BRCA2 PIK3C2A ARHGAP31 ANLN JAG1 TET1 SASS6 CPLANE1 PCNT	8.88e-05	1295	86	20	MP:0002088
Domain	Tet_JBP	TET2 TET1	3.07e-05	2	104	2	PF12851
Domain	2OGFeDO_noxygenase_dom	TET2 TET1	3.07e-05	2	104	2	IPR024779
Domain	SSFA2_C	ITPRID2 ITPRID1	3.07e-05	2	104	2	PF14723
Domain	SSFA2_C	ITPRID2 ITPRID1	3.07e-05	2	104	2	IPR029326
Domain	Tet_JBP	TET2 TET1	3.07e-05	2	104	2	SM01333
Domain	KRAP_IP3R_bind	ITPRID2 ITPRID1	9.18e-05	3	104	2	PF14722
Domain	MAP1	MAP1A MAP1B	9.18e-05	3	104	2	IPR026074
Domain	NXF_fam	NXF5 NXF2	9.18e-05	3	104	2	IPR030217
Domain	IP3R-bd	ITPRID2 ITPRID1	9.18e-05	3	104	2	IPR029325
Domain	KRAP_IP3R_bind	ITPRID2 ITPRID1	9.18e-05	3	104	2	SM01257
Domain	Tap-RNA_bind	NXF5 NXF2	1.83e-04	4	104	2	PF09162
Domain	Tap_RNA_bd	NXF5 NXF2	1.83e-04	4	104	2	PD043466
Domain	Tap_RNA-bd	NXF5 NXF2	1.83e-04	4	104	2	IPR015245
Domain	EGF_1	RELN ZAN NRXN3 MALRD1 EGF JAG1 USH2A	5.62e-04	255	104	7	PS00022
Domain	EGF	ZAN NRXN3 MALRD1 EGF JAG1	6.96e-04	126	104	5	PF00008
Domain	NTF2_DOMAIN	NXF5 NXF2	1.08e-03	9	104	2	PS50177
Domain	NTF2	NXF5 NXF2	1.08e-03	9	104	2	IPR002075
Domain	DOCK_C	DOCK2 DOCK7	1.63e-03	11	104	2	IPR010703
Domain	DHR-1_domain	DOCK2 DOCK7	1.63e-03	11	104	2	IPR027007
Domain	DHR_2	DOCK2 DOCK7	1.63e-03	11	104	2	PS51651
Domain	DHR_1	DOCK2 DOCK7	1.63e-03	11	104	2	PS51650
Domain	DOCK-C2	DOCK2 DOCK7	1.63e-03	11	104	2	PF14429
Domain	DHR-2	DOCK2 DOCK7	1.63e-03	11	104	2	IPR027357
Domain	DHR-2	DOCK2 DOCK7	1.63e-03	11	104	2	PF06920
Domain	DOCK	DOCK2 DOCK7	1.63e-03	11	104	2	IPR026791
Domain	RABBD	EXPH5 MYRIP	1.95e-03	12	104	2	PS50916
Domain	Rab_BD	EXPH5 MYRIP	1.95e-03	12	104	2	IPR010911
Domain	EGF_3	RELN ZAN NRXN3 MALRD1 EGF JAG1	2.03e-03	235	104	6	PS50026
Domain	EGF	RELN ZAN NRXN3 MALRD1 EGF JAG1	2.03e-03	235	104	6	SM00181
Domain	-	NXF5 NXF2	2.30e-03	13	104	2	3.10.450.50
Domain	EGF-like_dom	RELN ZAN NRXN3 MALRD1 EGF JAG1	2.70e-03	249	104	6	IPR000742
Domain	NTF2-like_dom	NXF5 NXF2	3.08e-03	15	104	2	IPR032710
Domain	PI3/4_kinase_CS	ATR PIK3C2A	3.08e-03	15	104	2	IPR018936
Domain	EGF-like_CS	RELN ZAN NRXN3 MALRD1 EGF JAG1	3.41e-03	261	104	6	IPR013032
Domain	-	ATR PIK3C2A	3.50e-03	16	104	2	1.10.1070.11
Domain	PI3Kc	ATR PIK3C2A	3.50e-03	16	104	2	SM00146
Domain	EGF_2	RELN ZAN NRXN3 MALRD1 EGF JAG1	3.67e-03	265	104	6	PS01186
Domain	MAM	ZAN MALRD1	3.95e-03	17	104	2	SM00137
Domain	MAM	ZAN MALRD1	4.43e-03	18	104	2	PF00629
Domain	PI3/4_kinase_cat_dom	ATR PIK3C2A	4.43e-03	18	104	2	IPR000403
Domain	PI3_PI4_kinase	ATR PIK3C2A	4.43e-03	18	104	2	PF00454
Domain	MAM_dom	ZAN MALRD1	4.43e-03	18	104	2	IPR000998
Domain	PI3_4_KINASE_3	ATR PIK3C2A	4.43e-03	18	104	2	PS50290
Domain	MAM_2	ZAN MALRD1	4.43e-03	18	104	2	PS50060
Domain	PI3_4_KINASE_1	ATR PIK3C2A	4.43e-03	18	104	2	PS00915
Domain	PI3_4_KINASE_2	ATR PIK3C2A	4.43e-03	18	104	2	PS00916
Domain	VWC_out	ZAN JAG1	4.94e-03	19	104	2	SM00215
Domain	-	MAP1A MAP1B	5.47e-03	20	104	2	3.60.15.10
Domain	Metallo-B-lactamas	MAP1A MAP1B	5.47e-03	20	104	2	IPR001279
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TET2 CASP8AP2 NCOA3 TSHZ3 PALB2 GREB1L JUP RESF1 BRCA2 TET1 DOCK7 PCNT NPAT	5.92e-10	418	107	13	34709266
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TET2 MAP1B EXPH5 PATZ1 MAP3K20 DYRK1A ITPRID2 E2F8 CEP350 JUP RESF1 PIK3C2A ANLN KIAA1217 TET1 DOCK7	9.22e-09	861	107	16	36931259
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	EPC2 VRK1 MAP1B DYRK1A CEP76 PALB2 KIF7 CEP350 ANLN RECQL5 SHPRH DOCK7 RAI1 PCNT	1.23e-08	645	107	14	25281560
Pubmed	Nuclear export factor family protein participates in cytoplasmic mRNA trafficking.	MAP1A MAP1B NXF5 NXF2	2.75e-08	11	107	4	16014633
Pubmed	A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.	MAP1B DYRK1A SPATS2L ANLN KIAA1217 DOCK7 PCNT	8.52e-08	118	107	7	30979931
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	TET2 NCOA3 ATR SPATS2L RESF1 BRCA2 MLF1	4.80e-07	152	107	7	38360978
Pubmed	Proximity interactions among centrosome components identify regulators of centriole duplication.	KIF7 CEP350 A2ML1 DOCK7 SASS6 PCNT	7.36e-07	101	107	6	24613305
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TET2 CASP8AP2 NACA WDR37 ZFYVE28 NRXN3 ARHGAP31 TET1 TMEM131L ARHGAP20 RAI1	7.56e-07	529	107	11	14621295
Pubmed	Downregulation of ten-eleven translocation-2 triggers epithelial differentiation during organogenesis.	TET2 CLDN10 TET1	1.57e-06	8	107	3	35569195
Pubmed	Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk.	ATR PALB2 BRCA2	3.34e-06	10	107	3	37592023
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	TET2 NCOA3 EPC2 TSHZ3 DYRK1A CEP76 RESF1 ANLN ZNF292	4.11e-06	398	107	9	35016035
Pubmed	Distributive Processing by the Iron(II)/α-Ketoglutarate-Dependent Catalytic Domains of the TET Enzymes Is Consistent with Epigenetic Roles for Oxidized 5-Methylcytosine Bases.	TET2 TET1	9.38e-06	2	107	2	27362828
Pubmed	Decrease of 5-hydroxymethylcytosine and TET1 with nuclear exclusion of TET2 in small intestinal neuroendocrine tumors.	TET2 TET1	9.38e-06	2	107	2	30045709
Pubmed	Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells.	TET2 TET1	9.38e-06	2	107	2	23415914
Pubmed	Regulation of microtubule-associated protein 1B (MAP1B) subunit composition.	MAP1A MAP1B	9.38e-06	2	107	2	11002287
Pubmed	The Polyploid State Plays a Tumor-Suppressive Role in the Liver.	E2F8 ANLN	9.38e-06	2	107	2	29429824
Pubmed	Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice.	TET2 TET1	9.38e-06	2	107	2	30540950
Pubmed	Tet1 Deficiency Leads to Premature Reproductive Aging by Reducing Spermatogonia Stem Cells and Germ Cell Differentiation.	TET2 TET1	9.38e-06	2	107	2	32114381
Pubmed	Early Expression of Tet1 and Tet2 in Mouse Zygotes Altered DNA Methylation Status and Affected Embryonic Development.	TET2 TET1	9.38e-06	2	107	2	35955629
Pubmed	Fanconi anemia is associated with a defect in the BRCA2 partner PALB2.	PALB2 BRCA2	9.38e-06	2	107	2	17200672
Pubmed	Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells.	TET2 TET1	9.38e-06	2	107	2	24474761
Pubmed	Rare germline variants in PALB2 and BRCA2 in familial and sporadic chordoma.	PALB2 BRCA2	9.38e-06	2	107	2	35762214
Pubmed	Microtubule association of a neuronal RNA-binding protein HuD through its binding to the light chain of MAP1B.	MAP1B ELAVL4	9.38e-06	2	107	2	21288476
Pubmed	Specific functions of TET1 and TET2 in regulating mesenchymal cell lineage determination.	TET2 TET1	9.38e-06	2	107	2	30606231
Pubmed	Ten-eleven translocation 2 modulates allergic inflammation by 5-hydroxymethylcytosine remodeling of immunologic pathways.	TET2 TET1	9.38e-06	2	107	2	34165552
Pubmed	Breast-cancer risk in families with mutations in PALB2.	PALB2 BRCA2	9.38e-06	2	107	2	25099575
Pubmed	Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.	PALB2 BRCA2	9.38e-06	2	107	2	22194698
Pubmed	Heterotypic complex formation between subunits of microtubule-associated proteins 1A and 1B is due to interaction of conserved domains.	MAP1A MAP1B	9.38e-06	2	107	2	16996626
Pubmed	Fanconi anemia gene mutations are not involved in sporadic Wilms tumor.	PALB2 BRCA2	9.38e-06	2	107	2	20589654
Pubmed	Tet-mediated imprinting erasure in H19 locus following reprogramming of spermatogonial stem cells to induced pluripotent stem cells.	TET2 TET1	9.38e-06	2	107	2	26328763
Pubmed	Analysis of PALB2/FANCN-associated breast cancer families.	PALB2 BRCA2	9.38e-06	2	107	2	17420451
Pubmed	The mouse and rat MAP1B genes: genomic organization and alternative transcription.	MAP1A MAP1B	9.38e-06	2	107	2	9615228
Pubmed	Structural basis for recruitment of BRCA2 by PALB2.	PALB2 BRCA2	9.38e-06	2	107	2	19609323
Pubmed	Mutations in BRCA2 and PALB2 in male breast cancer cases from the United States.	PALB2 BRCA2	9.38e-06	2	107	2	20927582
Pubmed	Delayed development of nervous system in mice homozygous for disrupted microtubule-associated protein 1B (MAP1B) gene.	MAP1A MAP1B	9.38e-06	2	107	2	9199175
Pubmed	Structural insight into substrate preference for TET-mediated oxidation.	TET2 TET1	9.38e-06	2	107	2	26524525
Pubmed	Cloning of human microtubule-associated protein 1B and the identification of a related gene on chromosome 15.	MAP1A MAP1B	9.38e-06	2	107	2	7806212
Pubmed	PALB2 regulates recombinational repair through chromatin association and oligomerization.	PALB2 BRCA2	9.38e-06	2	107	2	19423707
Pubmed	Genotype-cancer association in patients with Fanconi anemia due to pathogenic variants in FANCD1 (BRCA2) or FANCN (PALB2).	PALB2 BRCA2	9.38e-06	2	107	2	34687993
Pubmed	Redox-active quinones induces genome-wide DNA methylation changes by an iron-mediated and Tet-dependent mechanism.	TET2 TET1	9.38e-06	2	107	2	24214992
Pubmed	A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance.	PALB2 BRCA2	9.38e-06	2	107	2	21637299
Pubmed	Ten-eleven translocation protein 1 modulates medulloblastoma progression.	TET2 TET1	9.38e-06	2	107	2	33926529
Pubmed	Coordination of engineered factors with TET1/2 promotes early-stage epigenetic modification during somatic cell reprogramming.	TET2 TET1	9.38e-06	2	107	2	24672749
Pubmed	Two Missense Variants Detected in Breast Cancer Probands Preventing BRCA2-PALB2 Protein Interaction.	PALB2 BRCA2	9.38e-06	2	107	2	30410870
Pubmed	A primary role of TET proteins in establishment and maintenance of De Novo bivalency at CpG islands.	TET2 TET1	9.38e-06	2	107	2	27288448
Pubmed	Tet1 and Tet2 Protect DNA Methylation Canyons against Hypermethylation.	TET2 TET1	9.38e-06	2	107	2	26598602
Pubmed	Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample.	PALB2 BRCA2	9.38e-06	2	107	2	20872766
Pubmed	Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice.	TET2 TET1	9.38e-06	2	107	2	26586431
Pubmed	Flanking sequences influence the activity of TET1 and TET2 methylcytosine dioxygenases and affect genomic 5hmC patterns.	TET2 TET1	9.38e-06	2	107	2	35075236
Pubmed	Ten-Eleven Translocation 1 and 2 Confer Overlapping Transcriptional Programs for the Proliferation of Cultured Adult Neural Stem Cells.	TET2 TET1	9.38e-06	2	107	2	27778125
Pubmed	Neuronal abnormalities in microtubule-associated protein 1B mutant mice.	MAP1A MAP1B	9.38e-06	2	107	2	8577753
Pubmed	Molecular cloning of microtubule-associated protein 1 (MAP1A) and microtubule-associated protein 5 (MAP1B): identification of distinct genes and their differential expression in developing brain.	MAP1A MAP1B	9.38e-06	2	107	2	2355215
Pubmed	TET-dependent regulation of retrotransposable elements in mouse embryonic stem cells.	TET2 TET1	9.38e-06	2	107	2	27863519
Pubmed	Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism.	TET2 TET1	9.38e-06	2	107	2	28783731
Pubmed	Novel Epigenetic Controlling of Hypoxia Pathway Related to Overexpression and Promoter Hypomethylation of TET1 and TET2 in RPE Cells.	TET2 TET1	9.38e-06	2	107	2	28252217
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	PKD1L1 DYRK1A KIF7 CEP350 BRCA2 KIAA1217 MTMR2 MLF1 LRRCC1 SASS6 CPLANE1 PCNT	1.29e-05	853	107	12	28718761
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	DHX16 RELN NACA JUP ANLN KIAA1217 PRKCSH PCNT	1.63e-05	360	107	8	33111431
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	DHX16 TSHZ3 VRK1 ANLN RECQL5 SHPRH USF1 RAI1 ZNF292 NPAT	1.90e-05	608	107	10	36089195
Pubmed	The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly.	CEP76 SASS6 PCNT	2.65e-05	19	107	3	24421332
Pubmed	Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter.	TET2 TET1	2.81e-05	3	107	2	24194590
Pubmed	PRDM14 maintains pluripotency of embryonic stem cells through TET-mediated active DNA demethylation.	TET2 TET1	2.81e-05	3	107	2	26325469
Pubmed	TET proteins in malignant hematopoiesis.	TET2 TET1	2.81e-05	3	107	2	19923888
Pubmed	Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells.	TET2 TET1	2.81e-05	3	107	2	31433977
Pubmed	Two PALB2 germline mutations found in both BRCA1+ and BRCAx familial breast cancer.	PALB2 BRCA2	2.81e-05	3	107	2	25833210
Pubmed	A Survey of BRCA1, BRCA2, and PALB2 mutations in women with breast cancer in Trinidad and Tobago.	PALB2 BRCA2	2.81e-05	3	107	2	27469594
Pubmed	Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.	TET2 TET1	2.81e-05	3	107	2	21778364
Pubmed	Tet family proteins and 5-hydroxymethylcytosine in development and disease.	TET2 TET1	2.81e-05	3	107	2	22569552
Pubmed	The risk of breast cancer due to PALB2 gene mutations.	PALB2 BRCA2	2.81e-05	3	107	2	28791855
Pubmed	One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering.	TET2 TET1	2.81e-05	3	107	2	23992847
Pubmed	Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors.	PALB2 BRCA2	2.81e-05	3	107	2	33186520
Pubmed	Germline mutations of multiple breast cancer-related genes are differentially associated with triple-negative breast cancers and prognostic factors.	PALB2 BRCA2	2.81e-05	3	107	2	32029870
Pubmed	Breast cancer proteins PALB2 and BRCA2 stimulate polymerase η in recombination-associated DNA synthesis at blocked replication forks.	PALB2 BRCA2	2.81e-05	3	107	2	24485656
Pubmed	FLASH interacts with p160 coactivator subtypes and differentially suppresses transcriptional activity of steroid hormone receptors.	CASP8AP2 NCOA3	2.81e-05	3	107	2	15698540
Pubmed	A Phase I/II Study of Veliparib (ABT-888) in Combination with 5-Fluorouracil and Oxaliplatin in Patients with Metastatic Pancreatic Cancer.	PALB2 BRCA2	2.81e-05	3	107	2	32669374
Pubmed	Inhibition of Tet1- and Tet2-mediated DNA demethylation promotes immunomodulation of periodontal ligament stem cells.	TET2 TET1	2.81e-05	3	107	2	31611558
Pubmed	Identification and Management of Pathogenic Variants in BRCA1, BRCA2, and PALB2 in a Tumor-Only Genomic Testing Program.	PALB2 BRCA2	2.81e-05	3	107	2	35363308
Pubmed	The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.	TET2 TET1	2.81e-05	3	107	2	25915124
Pubmed	A Hypomorphic PALB2 Allele Gives Rise to an Unusual Form of FA-N Associated with Lymphoid Tumour Development.	PALB2 BRCA2	2.81e-05	3	107	2	26990772
Pubmed	Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.	PALB2 BRCA2	2.81e-05	3	107	2	16793542
Pubmed	Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine.	TET2 TET1	2.81e-05	3	107	2	23548903
Pubmed	Contribution of germline mutations in the BRCA and PALB2 genes to pancreatic cancer in Italy.	PALB2 BRCA2	2.81e-05	3	107	2	21989927
Pubmed	Interaction of tubby-like protein-1 (Tulp1) and microtubule-associated protein (MAP) 1A and MAP1B in the mouse retina.	MAP1A MAP1B	2.81e-05	3	107	2	24664738
Pubmed	5-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and function.	TET2 TET1	2.81e-05	3	107	2	34919053
Pubmed	Interaction of PDZRhoGEF with microtubule-associated protein 1 light chains: link between microtubules, actin cytoskeleton, and neuronal polarity.	MAP1A MAP1B	2.81e-05	3	107	2	16478718
Pubmed	Coupling of Homologous Recombination and the Checkpoint by ATR.	ATR PALB2	2.81e-05	3	107	2	28089683
Pubmed	Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development.	TET2 TET1	2.81e-05	3	107	2	23352810
Pubmed	Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development.	TET2 TET1	2.81e-05	3	107	2	21816367
Pubmed	Effect of aging on 5-hydroxymethylcytosine in brain mitochondria.	TET2 TET1	2.81e-05	3	107	2	22445327
Pubmed	IGF2BP1 expression in human mesenchymal stem cells significantly affects their proliferation and is under the epigenetic control of TET1/2 demethylases.	TET2 TET1	2.81e-05	3	107	2	24915579
Pubmed	TET-catalyzed oxidation of intragenic 5-methylcytosine regulates CTCF-dependent alternative splicing.	TET2 TET1	2.81e-05	3	107	2	26711177
Pubmed	TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23).	TET2 TET1	2.81e-05	3	107	2	12646957
Pubmed	Loss of Tet enzymes compromises proper differentiation of embryonic stem cells.	TET2 TET1	2.81e-05	3	107	2	24735881
Pubmed	PRDM14 promotes active DNA demethylation through the ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells.	TET2 TET1	2.81e-05	3	107	2	24335252
Pubmed	Analysis of large deletions in BRCA1, BRCA2 and PALB2 genes in Finnish breast and ovarian cancer families.	PALB2 BRCA2	2.81e-05	3	107	2	18501021
Pubmed	Polyglutamine repeat length in the AIB1 gene modifies breast cancer susceptibility in BRCA1 carriers.	NCOA3 BRCA2	2.81e-05	3	107	2	14648706
Pubmed	Breast cancer risk in BRCA1 and BRCA2 mutation carriers and polyglutamine repeat length in the AIB1 gene.	NCOA3 BRCA2	2.81e-05	3	107	2	15900600
Pubmed	Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.	TET2 TET1	2.81e-05	3	107	2	20639862
Pubmed	Ten-Eleven Translocation Genes are Downregulated in Endometriosis.	TET2 TET1	2.81e-05	3	107	2	26917261
Pubmed	BRCA and pancreatic cancer.	PALB2 BRCA2	2.81e-05	3	107	2	23846919
Pubmed	Alternation of ten-eleven translocation 1, 2, and 3 expression in eutopic endometrium of women with endometriosis-associated infertility.	TET2 TET1	2.81e-05	3	107	2	30130982
Interaction	YWHAH interactions	TET2 NCOA3 EXPH5 MAP3K20 DYRK1A ITPRID2 KRR1 WDR37 E2F8 KIF7 SYNGAP1 CEP350 JUP GRID2IP RESF1 PIK3C2A ANLN KIAA1217 TET1 DOCK7 PCNT	2.41e-07	1102	106	21	int:YWHAH
Interaction	LRCH1 interactions	DYRK1A PIK3C2A ANLN DOCK7 TMEM131L DSG4	1.18e-06	65	106	6	int:LRCH1
Interaction	KDM1A interactions	TET2 CASP8AP2 NCOA3 TSHZ3 CEP76 PALB2 GREB1L CEP350 C4orf17 KRT39 JUP RESF1 BRCA2 KIAA1217 TET1 DOCK7 PCNT NPAT	1.88e-06	941	106	18	int:KDM1A
Interaction	CFAP184 interactions	MAP1B EXPH5 ITPRID2 WDR37 CEP350 BRCA2 PIK3C2A PCNT	2.27e-06	162	106	8	int:CFAP184
Interaction	DUSP16 interactions	MAP1B EXPH5 ITPRID2 CEP350 BRCA2 PIK3C2A NXF2 MLF1 PCNT	4.51e-06	237	106	9	int:DUSP16
Interaction	PLEC interactions	TET2 ATR MAP1A NACA KRR1 KRT39 JUP BRCA2 ANLN MLF1 PCNT	1.66e-05	430	106	11	int:PLEC
Interaction	SYNE3 interactions	EXPH5 ITPRID2 PALB2 KIF7 CEP350 BRCA2 PIK3C2A KIAA1217 TMEM131L PRKCSH PCNT	2.23e-05	444	106	11	int:SYNE3
Interaction	FAM153CP interactions	MAP1A CAMK1 DSG4	2.26e-05	11	106	3	int:FAM153CP
Interaction	PRG4 interactions	MAP1B BRCA2 ANLN	4.94e-05	14	106	3	int:PRG4
Interaction	FGL2 interactions	ITPRID2 KIF7 PCNT	7.54e-05	16	106	3	int:FGL2
Interaction	LZTS2 interactions	DHX16 EXPH5 PATZ1 DYRK1A KIF7 BRCA2 PIK3C2A ANLN SH3RF2 KIAA1217 SASS6	8.07e-05	512	106	11	int:LZTS2
Interaction	YWHAG interactions	TET2 EXPH5 MAP3K20 DYRK1A ITPRID2 KRR1 WDR37 E2F8 KIF7 SYNGAP1 CEP350 JUP GRID2IP PIK3C2A ANLN TET1 SHPRH DOCK7	8.43e-05	1248	106	18	int:YWHAG
Interaction	CEP131 interactions	DYRK1A KIF7 BRCA2 NXF2 LRRCC1 SASS6 PCNT	9.08e-05	200	106	7	int:CEP131
Interaction	PRELID2 interactions	EXPH5 BRCA2 MLF1	9.12e-05	17	106	3	int:PRELID2
Interaction	MAGEA9 interactions	SAMD9 ITPRID2 TRMT2A BRCA2 PIK3C2A SHPRH MLF1	1.16e-04	208	106	7	int:MAGEA9
Interaction	NIN interactions	KIF7 CEP350 BRCA2 ANLN KIAA1217 LRRCC1 SASS6 CPLANE1 PCNT	1.18e-04	359	106	9	int:NIN
Interaction	HELQ interactions	DHX16 ATR BRCA2	1.51e-04	20	106	3	int:HELQ
Interaction	NINL interactions	NACA DYRK1A KIF7 CEP350 BRCA2 PIK3C2A KIAA1217 A2ML1 SASS6 PCNT	1.52e-04	458	106	10	int:NINL
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	CASP8AP2 EPC2 ATR MAP1B PDSS1 CEP76 PALB2 E2F8 CEP350 NRXN3 BRCA2 ANLN TET1 DOCK7 LRRCC1 TMEM131L SASS6 ELAVL4 CPLANE1 ZNF454 ZNF292	3.51e-06	1459	100	21	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_500	RGMB MAP1B DYRK1A MYRIP CEP350 NRXN3 TRMT2A PIK3C2A SHPRH ELAVL4 CPLANE1	4.24e-06	416	100	11	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_1000	NCOA3 RGMB ADAMTSL1 CALHM5 BCL2L11 MAP1B MAP3K20 DYRK1A E2F8 CEP350 RESF1 PIK3C2A SHPRH NECTIN4 CPLANE1	5.81e-06	811	100	15	gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#2_top-relative-expression-ranked_500	RGMB MAP1B DYRK1A CEP350 TRMT2A PIK3C2A SHPRH CPLANE1	6.60e-06	209	100	8	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_1000	RGMB TSHZ3 ADAMTSL1 CALHM5 BCL2L11 MAP1B MAP3K20 WDR37 NRXN3 SPATS2L ANLN NECTIN4 ELAVL4 CPLANE1 ZNF292	7.23e-06	826	100	15	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500	CASP8AP2 EPC2 RELN MAP1A MAP1B MYRIP CEP76 E2F8 NRXN3 BRCA2 ZNRF3 DOCK7 MLF1 LRRCC1 NECTIN4 TMEM131L SASS6 ELAVL4 ZNF454 ZNF292	8.12e-06	1414	100	20	facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1	CASP8AP2 EPC2 RELN MAP1A MAP1B MYRIP CEP76 E2F8 BRCA2 ZNRF3 DOCK7 MLF1 LRRCC1 TMEM131L SASS6 ZNF454 ZNF292	8.63e-06	1060	100	17	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#5_top-relative-expression-ranked_500	RGMB BCL2L11 MAP1B DYRK1A CEP350 SHPRH CPLANE1	1.31e-05	165	100	7	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k5_500
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	NCOA3 ATR BCL2L11 CHM PALB2 GREB1L ELL2 RESF1 BRCA2 SHPRH NXF2 MLF1 CPLANE1 NPAT	1.62e-05	776	100	14	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000	NCOA3 RGMB BCL2L11 MAP1B DYRK1A CEP350 RESF1 PIK3C2A SHPRH CPLANE1	1.81e-05	397	100	10	gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	CASP8AP2 EPC2 ATR PDSS1 CEP76 PALB2 E2F8 CEP350 BRCA2 ANLN TET1 DOCK7 LRRCC1 TMEM131L SASS6 CPLANE1 ZNF454 ZNF292	2.11e-05	1257	100	18	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500	NCOA3 BCL2L11 PATZ1 CHM WDR37 RESF1 KIAA1217 TET1 ARHGAP20 CPLANE1	2.19e-05	406	100	10	gudmap_developingGonad_e16.5_epididymis_500
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_500	NCOA3 BCL2L11 PATZ1 CHM WDR37 RESF1 KIAA1217 TET1 ARHGAP20 CPLANE1	2.53e-05	413	100	10	gudmap_developingGonad_e14.5_ epididymis_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_500	RGMB ADAMTSL1 CALHM5 BCL2L11 MAP1B MAP3K20 DYRK1A SHPRH NECTIN4 CPLANE1	2.98e-05	421	100	10	gudmap_developingLowerUrinaryTract_e14.5_ bladder_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#1	MAP1B CEP76 KRR1 ZFYVE28 PIK3C2A ANLN TET1 LRRCC1	3.11e-05	259	100	8	Facebase_RNAseq_e8.5_Floor Plate_1000_K1
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000	NCOA3 ADAMTSL1 BCL2L11 PATZ1 CHM WDR37 RESF1 ARHGAP31 KIAA1217 TET1 C2 ARHGAP20 CPLANE1	9.54e-05	799	100	13	gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000	NCOA3 BCL2L11 PATZ1 CHM WDR37 GREB1L ELL2 RESF1 KIAA1217 TET1 SHPRH ARHGAP20 CPLANE1	1.02e-04	804	100	13	gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000	RGMB ADAMTSL1 MAP1B DYRK1A MYRIP CEP350 NRXN3 TRMT2A PIK3C2A SHPRH NECTIN4 ELAVL4 CPLANE1	1.21e-04	818	100	13	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_200	RGMB TSHZ3 CALHM5 MAP1B PIK3C2A CPLANE1	1.27e-04	164	100	6	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000	RGMB BCL2L11 MAP1B DYRK1A CEP350 PIK3C2A SHPRH CPLANE1	1.68e-04	330	100	8	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#4_top-relative-expression-ranked_500	NCOA3 BCL2L11 PATZ1 KIAA1217 TET1 ARHGAP20	1.81e-04	175	100	6	gudmap_developingGonad_e14.5_ epididymis_500_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_500	RGMB BCL2L11 MAP1B DYRK1A MYRIP CEP350 SHPRH ELAVL4 CPLANE1	1.87e-04	427	100	9	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000	CASP8AP2 VRK1 ADAMTSL1 MAP1A MAP1B CEP350 ZFYVE28 NRXN3 PTPRJ BRCA2 LRRCC1 ELAVL4 ARHGAP20 PCNT	2.04e-04	983	100	14	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4	CASP8AP2 EPC2 RELN MAP1A MAP1B MYRIP FBXO11 CEP76 CHM WDR37 E2F8 BRCA2 DOCK7 LRRCC1 SASS6 ELAVL4 CPLANE1	2.12e-04	1370	100	17	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlas	facebase_RNAseq_e10.5_MaxArch_2500_K3	TET2 CASP8AP2 EPC2 ATR PDSS1 CEP76 GREB1L RESF1 BRCA2 TET1 DOCK7 LRRCC1 TMEM131L CPLANE1 ZNF454 ZNF292	2.39e-04	1252	100	16	facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	NCOA3 BCL2L11 PATZ1 CHM WDR37 NRXN3 RESF1 ARHGAP31 KIAA1217 TET1 ARHGAP20 CPLANE1	3.38e-04	790	100	12	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000	RGMB MAP1B DYRK1A CEP350 PIK3C2A SHPRH CPLANE1 ZNF292	3.57e-04	369	100	8	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000	NCOA3 BCL2L11 PATZ1 CHM WDR37 GREB1L ELL2 RESF1 KIAA1217 TET1 ARHGAP20 CPLANE1	4.05e-04	806	100	12	gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000	RGMB MAP1B DYRK1A CEP350 TRMT2A PIK3C2A SHPRH CPLANE1	4.73e-04	385	100	8	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlas	dev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500	WDR37 SYNGAP1 GREB1L ELL2 RESF1 PIK3C2A TMEM131L ARHGAP20	6.49e-04	404	100	8	gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_1000	RGMB BCL2L11 MAP1B CEP350 PIK3C2A SHPRH CPLANE1	6.89e-04	312	100	7	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#5_top-relative-expression-ranked_500	RGMB BCL2L11 MAP1B CEP350 CPLANE1	7.01e-04	149	100	5	gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#4_top-relative-expression-ranked_1000	RGMB MAP1B CEP350 PIK3C2A ARHGAP20	7.45e-04	151	100	5	gudmap_developingLowerUrinaryTract_P1_ureter_1000_k4
CoexpressionAtlas	Myeloid Cells, DC.8-4-11b+.MLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-2	ITPRID2 TNFRSF11A ELL2 PTPRJ ARHGAP31 JAG1 DOCK7 TMEM131L	7.49e-04	413	100	8	GSM538263_500
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	EXPH5 RTTN NRXN3 PTPRJ ZNRF3 PIK3C2A SDK1	3.52e-07	187	107	7	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	EXPH5 RTTN NRXN3 ZNRF3 PIK3C2A KIAA1217 SDK1	3.65e-07	188	107	7	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	MYRIP ITPRID1 CLDN10 EGF SH3RF2 KIAA1217 TET1	5.53e-07	200	107	7	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	RELN ADAMTSL1 RIT2 GREB1L NRXN3 USH2A	2.39e-06	159	107	6	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK2 RELN RIT2 GREB1L NRXN3 USH2A	2.75e-06	163	107	6	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TSHZ3 ADAMTSL1 SAMD9 MAP3K20 KIAA1217 HCRTR2	3.39e-06	169	107	6	1c9e54e7b14eb99996590fb93b257cf881a9f184
ToppCell	LPS-IL1RA-Epithelial_alveolar-Mes-Like-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NAT16 E2F8 BRCA2 KIAA1217 SASS6	5.04e-06	103	107	5	eb9f008b5fb8a01df8ea4faf6e6aebc1a9db9bd3
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	SHLD2 NCOA3 NRXN3 SPATS2L ZNRF3 SDK1	5.89e-06	186	107	6	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	SHLD2 NCOA3 NRXN3 SPATS2L ZNRF3 SDK1	5.89e-06	186	107	6	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B MAP3K20 NRXN3 JAG1 TMEM131L SDK1	6.45e-06	189	107	6	7fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B MAP3K20 NRXN3 JAG1 TMEM131L SDK1	6.45e-06	189	107	6	06b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell	NS-critical-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RTTN SLCO1B3 E2F8 BRCA2 ANLN PCNT	6.65e-06	190	107	6	7be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FBXO11 ELL2 PIK3C2A MLF1 ARHGAP20 FBXO34	7.06e-06	192	107	6	6bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCell	PSB-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RTTN E2F8 BRCA2 ANLN SASS6 PCNT	7.27e-06	193	107	6	b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCell	moderate-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RTTN E2F8 CEP350 BRCA2 ANLN PCNT	7.49e-06	194	107	6	dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCell	critical-Epithelial-FOXN4+\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RTTN SLCO1B3 E2F8 BRCA2 ANLN PCNT	8.41e-06	198	107	6	6b160b3d6a2c1b1641c2c7dcec1a7ef38411fec9
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 SAMD9 CEP350 JUP RESF1 ZNF292	8.91e-06	200	107	6	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TNFRSF11A ITPRID1 CLDN10 ELL2 EGF PTPRJ	8.91e-06	200	107	6	7c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYRIP TNFRSF11A ITPRID1 CLDN10 EGF KIAA1217	8.91e-06	200	107	6	85c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PATZ1 TNFRSF11A ITPRID1 CLDN10 ZNF454	2.48e-05	143	107	5	92ddc3e3f6ba78dd9daeb272c12503ec2650a874
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ADAMTSL1 ATR TNFRSF11A C2	3.87e-05	157	107	5	a426c54fd1545093d41426e9620862f71bd06f6b
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLCO1B3 E2F8 BRCA2 ANLN SASS6	4.63e-05	163	107	5	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	facs-Marrow-KLS-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHLD2 TNFRSF11A WDR37 JAG1 MLF1	4.63e-05	163	107	5	b83a35c4426d66b5734a98fa6c72b345fe462030
ToppCell	facs-Marrow-KLS-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHLD2 TNFRSF11A WDR37 JAG1 MLF1	4.63e-05	163	107	5	c20ca9b6b4170ebcb0e66eef3e5d8ebff22b1a91
ToppCell	Dividing_Macrophages-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	NAT16 E2F8 BRCA2 ANLN NECTIN4	5.05e-05	166	107	5	ea95b94ccc2ac67df741b30c27f4ae698925875f
ToppCell	Adult-Epithelial-lung_goblet_cell-D122\|Adult / Lineage, Cell type, age group and donor	ADAMTSL1 NRXN3 KIAA1217 NECTIN4 SDK1	5.20e-05	167	107	5	6efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell	Fetal_29-31_weeks-Epithelial-basal_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CLDN10 GREB1L NRXN3 KIAA1217 SDK1	5.35e-05	168	107	5	6521bead9789d626b86cbd08692c621c5a5aef33
ToppCell	LA-16._Neuronal\|LA / Chamber and Cluster_Paper	RELN NRXN3 PTPRJ ARHGAP31 KIAA1217	5.35e-05	168	107	5	c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CASP8AP2 VRK1 E2F8 BRCA2 ANLN	5.50e-05	169	107	5	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	Fetal_29-31_weeks-Epithelial-basal_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CLDN10 GREB1L NRXN3 KIAA1217 SDK1	5.50e-05	169	107	5	c3ee781735a9288ce1822b230d39bb91c1415589
ToppCell	facs\|World / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NCOA3 JUP ZNRF3 JAG1 MTMR2	5.81e-05	171	107	5	bb71e816dde44fda6af0ad98d979be9f8740fda6
ToppCell	facs\|World / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCOA3 JUP ZNRF3 JAG1 MTMR2	5.81e-05	171	107	5	5bcb96ed7fc15548f2dc9cf47482f890640cb39c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 TNFRSF11A E2F8 BRCA2 ANLN	5.81e-05	171	107	5	55c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCell	ASK440-Epithelial-Transformed_epithelium\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	BCL2L11 PDSS1 ZNRF3 NFKBIL1 SHPRH	5.98e-05	172	107	5	df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCell	ASK440-Epithelial-Transformed_epithelium\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	BCL2L11 PDSS1 ELL2 NFKBIL1 SHPRH	7.03e-05	178	107	5	86f1741636ed3e85bb4a65f84949b718fc38c290
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZAN SYNGAP1 ANLN C2 SDK1	7.03e-05	178	107	5	c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP1A E2F8 CEP350 BRCA2 ANLN	7.22e-05	179	107	5	d15182c668d7c37be8214cad9f1fe35d1409c9a1
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP1A E2F8 CEP350 BRCA2 ANLN	7.22e-05	179	107	5	e22a275a7c0ed19113c833a75d6c49fcc19aa13a
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	E2F8 SPATS2L ANLN TMEM131L PCNT	8.22e-05	184	107	5	a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	E2F8 SPATS2L ANLN TMEM131L PCNT	8.22e-05	184	107	5	081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCell	Control-Myeloid_G-immature_Neutrophil\|Control / Disease group, lineage and cell class	E2F8 SPATS2L ANLN TMEM131L PCNT	8.22e-05	184	107	5	45f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ZAN ELAVL4 USH2A SDK1	8.22e-05	184	107	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAP1B MYRIP ITPRID2 C4orf17 JAG1	8.22e-05	184	107	5	087666ba949b129c53d7ace40f9e543e3875a7de
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	E2F8 SPATS2L ANLN TMEM131L PCNT	8.22e-05	184	107	5	84c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	E2F8 SPATS2L ANLN TMEM131L PCNT	8.22e-05	184	107	5	d31d4116d1d196633784863781fa45673607a421
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ZAN ELAVL4 USH2A SDK1	8.22e-05	184	107	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	CASP8AP2 PIK3C2A ANLN TMEM131L PCNT	8.22e-05	184	107	5	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ZAN ELAVL4 USH2A SDK1	8.22e-05	184	107	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B MAP3K20 NRXN3 JAG1 TMEM131L	8.43e-05	185	107	5	51dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITPRID1 KRT39 SPATS2L PTPRJ A2ML1	8.43e-05	185	107	5	686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ADAMTSL1 E2F8 ELAVL4 C2	8.43e-05	185	107	5	bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	SHLD2 NCOA3 RELN ELL2 SPATS2L	8.43e-05	185	107	5	1d874608aa2062024323512f68889219471b2f00
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GREB1L SPATS2L NPAP1 DOCK7 SDK1	8.43e-05	185	107	5	d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B MAP3K20 NRXN3 JAG1 TMEM131L	8.43e-05	185	107	5	a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN MAP1B EXPH5 ZFYVE28 NRXN3	8.65e-05	186	107	5	d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	CASP8AP2 CEP350 RESF1 PIK3C2A NPAT	8.65e-05	186	107	5	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B MAP3K20 NRXN3 JAG1 TMEM131L	8.87e-05	187	107	5	ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B MAP3K20 NRXN3 JAG1 TMEM131L	8.87e-05	187	107	5	530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCell	Endothelial-Endothelial-E\|Endothelial / shred on cell class and cell subclass (v4)	MAP1B MYRIP ITPRID2 NRXN3 JAG1	9.09e-05	188	107	5	2777eb7689b271c199021fe7d9db88ccebff14de
ToppCell	COPD-Endothelial-VE_Capillary_A\|Endothelial / Disease state, Lineage and Cell class	NCOA3 EXPH5 ITPRID1 ARHGAP31 KIAA1217	9.09e-05	188	107	5	1aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	ADAMTSL1 MYRIP NRXN3 PIK3C2A ARHGAP31	9.32e-05	189	107	5	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP1A SLCO1B3 E2F8 BRCA2 ANLN	9.56e-05	190	107	5	0adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCell	NS-moderate-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RTTN E2F8 BRCA2 ANLN PCNT	9.56e-05	190	107	5	250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP1A SLCO1B3 E2F8 BRCA2 ANLN	9.56e-05	190	107	5	05455775845f4ded5c27e7b83242078d23162aaf
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	VRK1 RTTN E2F8 BRCA2 ANLN	9.56e-05	190	107	5	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	IPF-Epithelial-Goblet\|World / Disease state, Lineage and Cell class	JUP NRXN3 KIAA1217 NECTIN4 SDK1	9.56e-05	190	107	5	c29dabf0826663b9d6df51a7af9b76592090e44c
ToppCell	COVID-19-kidney-vSMC/Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	MAP1B MAP3K20 ELL2 JAG1 TMEM131L	9.80e-05	191	107	5	fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ADAMTSL1 EXPH5 CLDN10 GREB1L NECTIN4	9.80e-05	191	107	5	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	(04)_Pre-ciliated\|World / shred by cell type and Timepoint	MAP1A CEP76 E2F8 MLF1 PCNT	9.80e-05	191	107	5	37cf121e6e80760c8519075b7845b9029958a988
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK2 VRK1 E2F8 BRCA2 ANLN	9.80e-05	191	107	5	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	(1)_Control_(PBS)\|World / Stress and Cell class	MAP1B CLDN10 JUP ARHGAP31 C2	9.80e-05	191	107	5	b346e13259cb2d506b923ad44b894c21a3eee4c3
ToppCell	RA-09._Endothelium_I\|World / Chamber and Cluster_Paper	NCOA3 MYRIP PIK3C2A ARHGAP31 KIAA1217	9.80e-05	191	107	5	c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP3K20 NRXN3 JAG1 TMEM131L SDK1	1.00e-04	192	107	5	bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCell	RA-09._Endothelium_I\|RA / Chamber and Cluster_Paper	NCOA3 MYRIP PIK3C2A ARHGAP31 KIAA1217	1.00e-04	192	107	5	8a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP3K20 NRXN3 JAG1 TMEM131L SDK1	1.00e-04	192	107	5	b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ADAMTSL1 EXPH5 CLDN10 GREB1L NECTIN4	1.03e-04	193	107	5	b25cdca3a1e381784ae48ca73c51cbb6ac62b811
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ADAMTSL1 EXPH5 CLDN10 GREB1L NECTIN4	1.03e-04	193	107	5	b38aaffbea36ef6c08ebe82675438f873c89b242
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	VRK1 RTTN BRCA2 ANLN SASS6	1.03e-04	193	107	5	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	GREB1L ELL2 NRXN3 ZNRF3 SDK1	1.03e-04	193	107	5	503a979328c68b096680b71359a26f02fafdff35
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ADAMTSL1 EXPH5 CLDN10 GREB1L NECTIN4	1.05e-04	194	107	5	6b286992d4bb56013c0ea5a7601d3476d806175a
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ADAMTSL1 EXPH5 CLDN10 GREB1L NECTIN4	1.05e-04	194	107	5	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	ASK452-Endothelial-Lymphatic\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	TSHZ3 RELN MAP1B CEP76 MLF1	1.08e-04	195	107	5	20f492299a684ac1b7dd1bbc36a533cd6f9a1c93
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ADAMTSL1 EXPH5 CLDN10 GREB1L NECTIN4	1.08e-04	195	107	5	d673f8844896d5c7b76a7bc7f6b88a039f1bc263
ToppCell	COVID-19-kidney-Proliferating_T_cell\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK2 VRK1 E2F8 BRCA2 ANLN	1.08e-04	195	107	5	7e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CASP8AP2 VRK1 RTTN E2F8 BRCA2	1.08e-04	195	107	5	b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	VRK1 E2F8 BRCA2 ANLN PCNT	1.08e-04	195	107	5	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	LA-09._Endothelium_I\|LA / Chamber and Cluster_Paper	NCOA3 MYRIP PIK3C2A ARHGAP31 KIAA1217	1.13e-04	197	107	5	ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLDN10 JUP SH3RF2 KIAA1217 JAG1	1.16e-04	198	107	5	77517df37dc894c78ef1e2b24dd7ba31f928bdb7
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	E2F8 BRCA2 ANLN JAG1 SDK1	1.16e-04	198	107	5	f088badb90c6c2d916195f5649eda102119c9ac6
ToppCell	PSB\|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAP1B CLDN10 NRXN3 MLF1 SDK1	1.16e-04	198	107	5	4e6b0d1abc55d7a0d89bd7ecf0f13dc5bed66626
ToppCell	(11)_FOXN4+\|World / shred by cell type by condition	MAP1A E2F8 BRCA2 ANLN MLF1	1.16e-04	198	107	5	516b1acdf997dd8debc3dca066519366e507b414
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TSHZ3 ADAMTSL1 MAP1B KIF7 TET1	1.19e-04	199	107	5	a13f4b8a039304e685464cc8879659824cad5a3e
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAP1B E2F8 BRCA2 ANLN SASS6	1.19e-04	199	107	5	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ITPRID2 RESF1 PIK3C2A KIAA1217 PCNT	1.22e-04	200	107	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	EXPH5 JUP KIAA1217 NECTIN4 CPLANE1	1.22e-04	200	107	5	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAP1A MAP1B MAP3K20 JAG1 TMEM131L	1.22e-04	200	107	5	a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	RGMB CHM GREB1L NRXN3 ZNF292	1.22e-04	200	107	5	ac0e023dbb383bbc46c5cc525431778be8f7ef46
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAP1B JUP SPATS2L MLF1 NECTIN4	1.22e-04	200	107	5	1c02a7f4047d1d2208cc522c6bb4a4989d7845bb
ToppCell	critical-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RTTN CEP350 BRCA2 ANLN PCNT	1.22e-04	200	107	5	f39db4250ce220a3eb58edee3f7fc3671701d46f
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TSHZ3 JUP SH3RF2 KIAA1217 SDK1	1.22e-04	200	107	5	8827653738a931e4a4545e0c7d75be12bed40740
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	DYRK1A CEP76 CEP350 BRCA2 TMEM131L FBXO34 ZNF292 NPAT	2.58e-06	184	107	8	2321_DN
Disease	Autism Spectrum Disorders	TSHZ3 RELN NRXN3 TET1 USH2A RAI1	5.46e-07	85	103	6	C1510586
Disease	Intellectual Disability	VRK1 MAP1B RTTN WDR37 KIF7 SYNGAP1 NXF5 RAI1 ZNF292	2.77e-05	447	103	9	C3714756
Disease	Seckel syndrome 1	ATR PCNT	3.61e-05	3	103	2	C4551474
Disease	response to cranial radiation therapy, short-term memory	EPC2 MAP3K20 NRXN3 MALRD1	5.88e-05	60	103	4	EFO_0004335, EFO_0010950
Disease	Prostatic Neoplasms	TET2 NCOA3 RGMB SAMD9 ATR PALB2 JUP EGF BRCA2 ZNF292	6.05e-05	616	103	10	C0033578
Disease	Malignant neoplasm of prostate	TET2 NCOA3 RGMB SAMD9 ATR PALB2 JUP EGF BRCA2 ZNF292	6.05e-05	616	103	10	C0376358
Disease	Down syndrome (is_marker_for)	RELN DYRK1A PCNT	6.06e-05	22	103	3	DOID:14250 (is_marker_for)
Disease	Corneal Opacity	WDR37 JAG1	7.21e-05	4	103	2	C0010038
Disease	breast cancer (implicated_via_orthology)	NCOA3 ATR BRCA2	8.98e-05	25	103	3	DOID:1612 (implicated_via_orthology)
Disease	MYELODYSPLASTIC SYNDROME	TET2 SAMD9 PALB2 BRCA2	9.06e-05	67	103	4	C3463824
Disease	mean reticulocyte volume	SAMD9 ATR BCL2L11 RTTN DYRK1A E2F8 CEP350 RESF1 PTPRJ KIAA1217 TMEM131L	1.11e-04	799	103	11	EFO_0010701
Disease	hereditary breast ovarian cancer syndrome (is_implicated_in)	PALB2 BRCA2	1.20e-04	5	103	2	DOID:5683 (is_implicated_in)
Disease	hypothyroidism (biomarker_via_orthology)	RELN MAP1A MAP1B ELAVL4	1.81e-04	80	103	4	DOID:1459 (biomarker_via_orthology)
Disease	autism spectrum disorder (implicated_via_orthology)	TSHZ3 DYRK1A SYNGAP1 NRXN3 SH3RF2	1.98e-04	152	103	5	DOID:0060041 (implicated_via_orthology)
Disease	Urogenital Abnormalities	SAMD9 WDR37	2.51e-04	7	103	2	C0042063
Disease	OROFACIODIGITAL SYNDROME VI	KIF7 CPLANE1	2.51e-04	7	103	2	C2745997
Disease	Abnormality of the skeletal system	WDR37 ZNF292	3.33e-04	8	103	2	C4021790
Disease	age at first sexual intercourse measurement	MAP3K20 RIT2 ELL2 C2 SDK1 HCRTR2 ZNF292	4.00e-04	383	103	7	EFO_0009749
Disease	Pancreatic carcinoma, familial	PALB2 BRCA2	4.28e-04	9	103	2	C2931038
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	TET2 TSHZ3 MAP3K20 FBXO11 RIT2 NRXN3 SPATS2L ELAVL4 USH2A SDK1	5.00e-04	801	103	10	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	Abnormality of nervous system morphology	WDR37 ZNF292	5.33e-04	10	103	2	C4022810
Disease	HbA1c measurement	TET2 JUP EGF PTPRJ TET1 NFKBIL1 TMEM131L PRKCSH RAI1	6.04e-04	675	103	9	EFO_0004541
Disease	neuropsychological test	TSHZ3 ADAMTSL1 RIT2 NRXN3 KIAA1217	6.50e-04	197	103	5	EFO_0003926
Disease	pneumococcal bacteremia	DOCK2 DOCK7	6.50e-04	11	103	2	EFO_1001925
Disease	autosomal dominant nonsyndromic deafness (is_implicated_in)	MAP1B GREB1L	6.50e-04	11	103	2	DOID:0050564 (is_implicated_in)
Disease	abdominal fat cell number	ITPRID1 C4orf17 SPATS2L SH3RF2 KIAA1217	6.65e-04	198	103	5	EFO_0021534
Disease	X-24588 measurement	PDSS1 SLCO1B3	9.18e-04	13	103	2	EFO_0800898
Disease	multiple myeloma, monoclonal gammopathy	ELL2 ULK4	1.07e-03	14	103	2	EFO_0000203, EFO_0001378
Disease	Fanconi anemia	PALB2 BRCA2	1.07e-03	14	103	2	cv:C0015625
Disease	Hereditary Breast and Ovarian Cancer Syndrome	PALB2 BRCA2	1.07e-03	14	103	2	C0677776
Disease	Cardiovascular Abnormalities	WDR37 ZNF292	1.40e-03	16	103	2	C0243050
Disease	Profound Mental Retardation	VRK1 KIF7 SYNGAP1 RAI1	1.45e-03	139	103	4	C0020796
Disease	Mental Retardation, Psychosocial	VRK1 KIF7 SYNGAP1 RAI1	1.45e-03	139	103	4	C0025363
Disease	Mental deficiency	VRK1 KIF7 SYNGAP1 RAI1	1.45e-03	139	103	4	C0917816
Disease	Moyamoya Disease	JAG1 PCNT	1.59e-03	17	103	2	C0026654
Disease	acute lymphoblastic leukemia	MYRIP RIT2 PTPRJ	1.61e-03	66	103	3	EFO_0000220
Disease	adiponectin measurement	MAP3K20 NRXN3 EGF SASS6	1.74e-03	146	103	4	EFO_0004502
Disease	late-onset myasthenia gravis	TNFRSF11A NFKBIL1	1.78e-03	18	103	2	EFO_1001490
Disease	Bone marrow hypocellularity	PALB2 BRCA2	1.78e-03	18	103	2	C1855710
Disease	Prostate cancer, familial	DOCK2 BCL2L11 BRCA2	1.83e-03	69	103	3	C2931456
Disease	Chronic myeloproliferative disorder	ATR PCNT	1.99e-03	19	103	2	C1292778
Disease	acute lymphoblastic leukemia, response to antineoplastic agent	NCOA3 SPATS2L	1.99e-03	19	103	2	EFO_0000220, GO_0097327
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	PALB2 PTPRJ	1.99e-03	19	103	2	C1333991
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	PALB2 PTPRJ	1.99e-03	19	103	2	C2936783
Disease	eosinophil count	DHX16 TET2 ATR BCL2L11 PATZ1 DYRK1A RESF1 PTPRJ JAG1 NFKBIL1 PRKCSH RAI1 ZNF292	2.03e-03	1488	103	13	EFO_0004842
Disease	monocyte count	TET2 BCL2L11 ZFYVE28 OR52I2 OR52I1 EGF JAG1 NFKBIL1 TMEM131L USF1 RAI1 NPAT	2.19e-03	1320	103	12	EFO_0005091
Disease	Familial aplasia of the vermis	KIF7 CPLANE1	2.20e-03	20	103	2	cv:C0431399
Disease	Adenocarcinoma of prostate	PALB2 BRCA2	2.20e-03	20	103	2	C0007112
Disease	alpha-tocopherol measurement	DYRK1A USH2A	2.20e-03	20	103	2	EFO_0007898
Disease	Autistic Disorder	RELN SYNGAP1 NRXN3 EGF ZNF292	2.26e-03	261	103	5	C0004352
Disease	Seckel syndrome	ATR PCNT	2.66e-03	22	103	2	C0265202
Disease	small cell lung carcinoma	ADAMTSL1 BRCA2 A2ML1	2.79e-03	80	103	3	EFO_0000702
Disease	susceptibility to shingles measurement	DHX16 MYRIP C2	2.89e-03	81	103	3	EFO_0008401
Disease	serum alanine aminotransferase measurement	EXPH5 PKD1L1 MAP3K20 DYRK1A SLCO1B3 C4orf17 RESF1 PTPRJ TET1	3.41e-03	869	103	9	EFO_0004735
Disease	Fanconi Anemia	PALB2 BRCA2	3.44e-03	25	103	2	C0015625

Protein segments in the cluster

Peptide	Gene	Start	Entry
PKAQGSSTSDCMSKT	EPC2	616	Q52LR7
SSGGVKEDCTASMEP	ELL2	506	O00472
CSMSGKSPVESSLNV	FBXO34	71	Q9NWN3
TDKTGCFSAPVDMAT	A2ML1	286	A8K2U0
EAPTASGSSEAMQKC	ALPK3	1741	Q96L96
TDRSPAPMSCDKSTQ	BCL2L11	101	O43521
CPSPMQTGATTDDSK	ELAVL4	36	P26378
MSEEAIKSVCAPGAT	CEP76	491	Q8TAP6
MHTGGETSACKPSSV	DYRK1A	1	Q13627
MESLTVTPCSKASAN	DHX16	706	O60231
DSTGVSNCKDFPSML	CLDN10	56	P78369
PKSSGVCDSESSMQV	CASP8AP2	586	Q9UKL3
TCVPSTSAEDMSENV	CHM	186	P24386
CSVTSPDDMSTKSDD	RAI1	556	Q7Z5J4
STAGSCSSDKMGPEA	ZFYVE28	686	Q9HCC9
CSPASETGSENSVNM	NPAT	1316	Q14207
ISITTVSCGKMAAPT	PTPRJ	791	Q12913
SSTVVMQDESFPACK	MAP1A	2786	P78559
SSTVVMQDESFPACK	MAP1B	2451	P46821
KSVSLDSGFSSICPM	ITPRID1	781	Q6ZRS4
MDTKGCTTTNSPSTP	KRT39	1	Q6A163
GKETMVTSTTEPSRC	PRKCSH	486	P14314
NSSTEPKGFTECEMT	ANLN	501	Q9NQW6
TSCAEVVSQEKTMFP	C2	636	P06681
DMSNSSTTEGCMGPV	DSG4	976	Q86SJ6
KASGISTPVSNDMCT	ADAMTSL1	1576	Q8N6G6
SETMKPCKENFTGSE	NXF5	261	Q9H1B4
MAQISSNSGFKECPS	PIK3C2A	1	O00443
MKLEASCGTATSEVP	NAT16	1	Q8N8M0
GNAKTVMIACVSPSS	KIF7	316	Q2M1P5
MEKSSSCESLGSQPA	MTMR2	1	Q13614
SGTPSCENLKMSVNS	EXPH5	1306	Q8NEV8
EGSMTVCTTKKTFDP	KRR1	96	Q13601
EEASTSVCRPKSSMA	NFKBIL1	11	Q9UBC1
CDSLGPQMASSTTSK	GREB1L	1186	Q9C091
AKCSDMSSENTTGPP	ITPRID2	671	P28290
EKSECQDMSLSSPTS	PCNT	2181	O95613
NTCVPSVSSKGIMEE	JUP	31	P14923
EQDTCSTSPFAMSKS	H1-10-AS1	26	Q4G0G2
EGMVKNETFCAATPS	RELN	1261	P78509
SKMEDPGSVLSTACG	CAMK1	166	Q14012
TPEKQSANGSFSCDM	PATZ1	576	Q9HBE1
LKNPSGSCSVDVSAM	PALB2	861	Q86YC2
TTSKSFPASLGMCTV	MALRD1	1796	Q5VYJ5
MECSTVFPGLANKTT	HCRTR2	191	O43614
CNKPVDGSSSTLSMS	ATR	2226	Q13535
ACQSISPSSEDKFAM	GRID2IP	1116	A4D2P6
TKPTSSSCMDFEGAN	E2F8	831	A0AVK6
ISLASMNSDCSTPSK	DOCK2	1646	Q92608
MNSDCSTPSKPTSES	DOCK2	1651	Q92608
SNAMPVIFGKSSCSE	DOCK7	596	Q96N67
STPVSAQMTSKSCKG	BRCA2	3241	P51587
TSPGMNSSDELCESV	CPLANE1	2821	Q9H799
SSDKGSCPQVMERSF	EGF	1151	P01133
TACPTKNSMEGASTS	FBXO11	111	Q86XK2
DFTSCSDQMGKPTSA	PDSS1	311	Q5T2R2
VSCGKTSMLPTVNEE	CALHM5	156	Q8N5C1
TPGSCSSGMTSTKND	C4orf17	151	Q53FE4
APTSTAVCDSVMDTK	CEP350	51	Q5VT06
ESMSNDTSLPDKCNS	MAP3K20	261	Q9NYL2
CSTGKGISTMEESVT	SDK1	2041	Q7Z5N4
QSGATISMPCSTDKE	SASS6	576	Q6UVJ0
GTTSAAAPCSLKMEA	PKD1L1	176	Q8TDX9
SCSGPLVMASDSDVK	FAM181A	56	Q8N9Y4
DSCTVAMASNDTPEG	JAG1	576	P78504
SSETMKPCKENFTGS	NXF2	371	Q9GZY0
VVPKMVSIFCSGDSS	OR52I1	81	Q8NGK6
SVVPKMVSIFCSGDS	OR52I2	106	Q8NH67
NSICPAPSTMSKAEE	RPIA	66	P49247
CMKSHEEIEPGSQSS	ARHGAP20	1136	Q9P2F6
SKASSDTEEMLPCTT	RTTN	741	Q86VV8
SCGVSSRMFVKTPEA	USH2A	3851	O75445
MSQRNCSKDGPTSST	RGMB	116	Q6NW40
KPMESCGQESSSALS	TRMT2A	11	Q8IZ69
GPMNGCEKDSSSTDS	SPATS2L	106	Q9NUQ6
FSNPSSECSMKEGIQ	TMEM131L	1066	A2VDJ0
PAKSDSSCSMEVLAT	RESF1	661	Q9HCM1
MEVENEASCSPGSAS	RIT2	1	Q99578
AMIQNCADSSKPTST	SAMD9	716	Q5K651
TKDSLSMTSEAGLPC	NRXN3	371	Q9HDB5
GVDNKMSQCTSSTIP	NCOA3	761	Q9Y6Q9
SEMSPKALVDTSCSS	KIAA1217	1681	Q5T5P2
TSSNMQICGFKSTVP	SHLD2	116	Q86V20
CPATSDSGITDVAMS	SHPRH	601	Q149N8
MSEKAQASPASSCLE	NPAP1	221	Q9NZP6
TSGSPKMFAQDTVCA	TET1	236	Q8NFU7
KGSCPFQTATELMET	RECQL5	661	O94762
CTSSSDITEPEQKML	SYNGAP1	821	Q96PV0
MSEGESKDSSGSECP	RNF222	1	A6NCQ9
VPSAGTDSKTCNLDM	SLCO1B3	681	Q9NPD5
CSSSVMTYSKIGDEP	MLF1	106	P58340
SMTASVDVGKFPCDQ	ZNF292	2206	O60281
SMDSLCSVPVEGKET	ARHGAP31	346	Q2M1Z3
CSSEVGEPIKMEASS	TSHZ3	646	Q63HK5
MNSSESVGSDAPCVV	VRK1	56	Q99986
MPTESASCSTARQTK	WDR37	1	Q9Y2I8
ASPSGDQVSTCSLEM	ZNRF3	651	Q9ULT6
NTPSQECDESGSTMS	ZNF454	146	Q8N9F8
MEKADVPSSCVGQVS	SH3RF2	341	Q8TEC5
QTAGTMTVPLCSEKT	TET2	491	Q6N021
SPGEDMTHCSPQKTS	ULK4	376	Q96C45
EPGKYMSSKCTTTSD	TNFRSF11A	51	Q9Y6Q6
IPDCSMESTKSGQSK	USF1	226	P22415
TMTTTCQDAGHAVKP	ZAN	1401	Q9Y493
DVSSCRSSFPETMNK	LEG1	171	Q6P5S2
TSFMSVCQSSEPEKN	LRRCC1	271	Q9C099
SVTCKMGATVPQASK	NACA	1656	E9PAV3
PNPEAMCSDSETSSA	MYRIP	446	Q8NFW9
SLKDNSSCSVMSEEP	NECTIN4	426	Q96NY8