Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	regulation of embryonic development	LAMA2 LAMA5 TENM4 JAG1 LAMA1	3.54e-07	99	31	5	GO:0045995
GeneOntologyBiologicalProcess	regulation of basement membrane organization	LAMA2 LAMA1	1.19e-04	11	31	2	GO:0110011
GeneOntologyBiologicalProcess	morphogenesis of a polarized epithelium	LAMA5 ASTN2 LAMA1	1.78e-04	73	31	3	GO:0001738
GeneOntologyBiologicalProcess	embryo development	LAMA2 LAMA5 SP9 SP8 KMT2D TENM4 FZD5 JAG1 LAMA1	1.87e-04	1437	31	9	GO:0009790
GeneOntologyBiologicalProcess	positive regulation of integrin-mediated signaling pathway	LAMA2 LAMA1	1.97e-04	14	31	2	GO:2001046
GeneOntologyBiologicalProcess	morphogenesis of an epithelium	LAMA5 ASTN2 LGR5 FZD5 JAG1 LAMA1	2.77e-04	619	31	6	GO:0002009
GeneOntologyCellularComponent	laminin complex	LAMA5 LAMA1	9.51e-05	10	31	2	GO:0043256
GeneOntologyCellularComponent	clathrin-coated endocytic vesicle membrane	KIAA0319 BTC FZD5	2.16e-04	79	31	3	GO:0030669
GeneOntologyCellularComponent	protein complex involved in cell-matrix adhesion	LAMA2 LAMA1	2.85e-04	17	31	2	GO:0098637
GeneOntologyCellularComponent	clathrin-coated vesicle	KIAA0319 ASTN2 BTC FZD5	3.98e-04	237	31	4	GO:0030136
GeneOntologyCellularComponent	clathrin-coated endocytic vesicle	KIAA0319 BTC FZD5	4.46e-04	101	31	3	GO:0045334
GeneOntologyCellularComponent	basement membrane	LAMA2 LAMA5 LAMA1	7.74e-04	122	31	3	GO:0005604
GeneOntologyCellularComponent	synaptic cleft	LAMA2 LAMA5	1.09e-03	33	31	2	GO:0043083
GeneOntologyCellularComponent	clathrin-coated vesicle membrane	KIAA0319 BTC FZD5	1.33e-03	147	31	3	GO:0030665
GeneOntologyCellularComponent	coated vesicle	KIAA0319 ASTN2 BTC FZD5	1.88e-03	360	31	4	GO:0030135
GeneOntologyCellularComponent	protein complex involved in cell adhesion	LAMA2 LAMA1	3.45e-03	59	31	2	GO:0098636
GeneOntologyCellularComponent	early endosome membrane	KIAA0319 FZD5 PLEKHF2	3.75e-03	212	31	3	GO:0031901
GeneOntologyCellularComponent	endocytic vesicle membrane	KIAA0319 BTC FZD5	3.75e-03	212	31	3	GO:0030666
GeneOntologyCellularComponent	coated vesicle membrane	KIAA0319 BTC FZD5	3.90e-03	215	31	3	GO:0030662
GeneOntologyCellularComponent	early endosome	KIAA0319 ASTN2 FZD5 PLEKHF2	5.32e-03	481	31	4	GO:0005769
GeneOntologyCellularComponent	collagen-containing extracellular matrix	LAMA2 LAMA5 GDF15 LAMA1	7.47e-03	530	31	4	GO:0062023
GeneOntologyCellularComponent	neuromuscular junction	LAMA2 LAMA5	1.20e-02	112	31	2	GO:0031594
GeneOntologyCellularComponent	trans-Golgi network membrane	ST3GAL1 LGR5	1.20e-02	112	31	2	GO:0032588
Domain	Laminin_aI	LAMA2 LAMA5 LAMA1	4.13e-08	5	31	3	IPR009254
Domain	Laminin_I	LAMA2 LAMA5 LAMA1	4.13e-08	5	31	3	PF06008
Domain	Laminin_II	LAMA2 LAMA5 LAMA1	4.13e-08	5	31	3	PF06009
Domain	Laminin_domII	LAMA2 LAMA5 LAMA1	4.13e-08	5	31	3	IPR010307
Domain	EGF_1	LAMA2 LAMA5 ASTN2 TENM4 BTC JAG1 LAMA1	1.62e-07	255	31	7	PS00022
Domain	EGF_2	LAMA2 LAMA5 ASTN2 TENM4 BTC JAG1 LAMA1	2.10e-07	265	31	7	PS01186
Domain	LAMININ_IVA	LAMA2 LAMA5 LAMA1	2.31e-07	8	31	3	PS51115
Domain	Laminin_B	LAMA2 LAMA5 LAMA1	2.31e-07	8	31	3	PF00052
Domain	LamB	LAMA2 LAMA5 LAMA1	2.31e-07	8	31	3	SM00281
Domain	Laminin_IV	LAMA2 LAMA5 LAMA1	2.31e-07	8	31	3	IPR000034
Domain	EGF	LAMA2 LAMA5 TENM4 BTC JAG1 LAMA1	2.11e-06	235	31	6	SM00181
Domain	LAMININ_NTER	LAMA2 LAMA5 LAMA1	2.28e-06	16	31	3	PS51117
Domain	Laminin_N	LAMA2 LAMA5 LAMA1	2.28e-06	16	31	3	PF00055
Domain	Laminin_N	LAMA2 LAMA5 LAMA1	2.28e-06	16	31	3	IPR008211
Domain	LamNT	LAMA2 LAMA5 LAMA1	2.28e-06	16	31	3	SM00136
Domain	EGF-like_dom	LAMA2 LAMA5 TENM4 BTC JAG1 LAMA1	2.94e-06	249	31	6	IPR000742
Domain	EGF-like_CS	LAMA2 LAMA5 TENM4 BTC JAG1 LAMA1	3.86e-06	261	31	6	IPR013032
Domain	ZnF_NFX	NFXL1 NFX1	7.99e-06	3	31	2	SM00438
Domain	zf-NF-X1	NFXL1 NFX1	7.99e-06	3	31	2	PF01422
Domain	Znf_NFX1	NFXL1 NFX1	7.99e-06	3	31	2	IPR000967
Domain	EGF_LAM_2	LAMA2 LAMA5 LAMA1	1.63e-05	30	31	3	PS50027
Domain	EGF_LAM_1	LAMA2 LAMA5 LAMA1	1.63e-05	30	31	3	PS01248
Domain	Laminin_EGF	LAMA2 LAMA5 LAMA1	2.61e-05	35	31	3	PF00053
Domain	EGF_Lam	LAMA2 LAMA5 LAMA1	2.61e-05	35	31	3	SM00180
Domain	LAM_G_DOMAIN	LAMA2 LAMA5 LAMA1	3.36e-05	38	31	3	PS50025
Domain	Laminin_EGF	LAMA2 LAMA5 LAMA1	3.36e-05	38	31	3	IPR002049
Domain	Laminin_G_2	LAMA2 LAMA5 LAMA1	3.92e-05	40	31	3	PF02210
Domain	LamG	LAMA2 LAMA5 LAMA1	5.24e-05	44	31	3	SM00282
Domain	Sp1_fam	SP9 SP8	1.19e-04	10	31	2	IPR030450
Domain	Laminin_G	LAMA2 LAMA5 LAMA1	1.20e-04	58	31	3	IPR001791
Domain	Laminin_G_1	LAMA2 LAMA1	1.45e-04	11	31	2	PF00054
Domain	ConA-like_dom	LAMA2 LAMA5 TRIM36 LAMA1	4.51e-04	219	31	4	IPR013320
Domain	Galactose-bd-like	LAMA2 LAMA5 LAMA1	5.01e-04	94	31	3	IPR008979
Domain	-	LAMA2 LAMA5 LAMA1	5.17e-04	95	31	3	2.60.120.200
Domain	EGF_3	ASTN2 TENM4 BTC JAG1	5.89e-04	235	31	4	PS50026
Domain	FYVE	PLEKHF2 FGD3	1.05e-03	29	31	2	PF01363
Domain	FYVE	PLEKHF2 FGD3	1.05e-03	29	31	2	SM00064
Domain	ZF_RING_1	NFXL1 KMT2D TRIM36 NFX1	1.30e-03	291	31	4	PS00518
Domain	ZF_RING_2	NFXL1 KMT2D TRIM36 NFX1	1.42e-03	298	31	4	PS50089
Domain	Znf_FYVE-rel	PLEKHF2 FGD3	1.45e-03	34	31	2	IPR017455
Domain	Znf_FYVE	PLEKHF2 FGD3	1.81e-03	38	31	2	IPR000306
Domain	Znf_FYVE_PHD	KMT2D PLEKHF2 FGD3	1.83e-03	147	31	3	IPR011011
Domain	Znf_RING	NFXL1 KMT2D TRIM36 NFX1	1.98e-03	326	31	4	IPR001841
Domain	ZF_FYVE	PLEKHF2 FGD3	2.00e-03	40	31	2	PS50178
Domain	Growth_fac_rcpt_	LAMA5 JAG1 LAMA1	2.16e-03	156	31	3	IPR009030
Domain	FN3	KIAA0319 ASTN2 TRIM36	3.50e-03	185	31	3	SM00060
Domain	EGF_extracell	TENM4 JAG1	4.44e-03	60	31	2	IPR013111
Domain	EGF_2	TENM4 JAG1	4.44e-03	60	31	2	PF07974
Domain	FN3_dom	KIAA0319 ASTN2 TRIM36	4.93e-03	209	31	3	IPR003961
Domain	Zinc_finger_PHD-type_CS	NFXL1 NFX1	5.20e-03	65	31	2	IPR019786
Domain	Znf_C2H2/integrase_DNA-bd	ZNF202 SP9 SP8 OVOL3 ZNF425	5.32e-03	694	31	5	IPR013087
Domain	-	KMT2D TRIM36 PLEKHF2 FGD3	6.20e-03	449	31	4	3.30.40.10
Domain	Znf_RING/FYVE/PHD	KMT2D TRIM36 PLEKHF2 FGD3	6.70e-03	459	31	4	IPR013083
Domain	Znf_PHD-finger	KMT2D NFX1	7.59e-03	79	31	2	IPR019787
Domain	ZINC_FINGER_C2H2_2	ZNF202 SP9 SP8 OVOL3 ZNF425	8.42e-03	775	31	5	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF202 SP9 SP8 OVOL3 ZNF425	8.51e-03	777	31	5	PS00028
Pathway	PID_INTEGRIN4_PATHWAY	LAMA2 LAMA5 LAMA1	5.40e-07	11	22	3	M158
Pathway	REACTOME_MET_ACTIVATES_PTK2_SIGNALING	LAMA2 LAMA5 LAMA1	1.30e-05	30	22	3	M27772
Pathway	REACTOME_LAMININ_INTERACTIONS	LAMA2 LAMA5 LAMA1	1.30e-05	30	22	3	M27216
Pathway	WP_ALPHA_6_BETA_4_SIGNALING	LAMA2 LAMA5 LAMA1	1.75e-05	33	22	3	M39503
Pathway	REACTOME_MET_PROMOTES_CELL_MOTILITY	LAMA2 LAMA5 LAMA1	3.38e-05	41	22	3	M27778
Pathway	PID_A6B1_A6B4_INTEGRIN_PATHWAY	LAMA2 LAMA5 LAMA1	4.79e-05	46	22	3	M239
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	LAMA2 LAMA5 LAMA1	1.01e-04	59	22	3	M27218
Pathway	WP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY	LAMA2 LAMA5 LAMA1	1.42e-04	66	22	3	MM15925
Pathway	PID_INTEGRIN1_PATHWAY	LAMA2 LAMA5 LAMA1	1.42e-04	66	22	3	M18
Pathway	REACTOME_ECM_PROTEOGLYCANS	LAMA2 LAMA5 LAMA1	2.15e-04	76	22	3	M27219
Pathway	REACTOME_SIGNALING_BY_MET	LAMA2 LAMA5 LAMA1	2.42e-04	79	22	3	M27643
Pathway	KEGG_SMALL_CELL_LUNG_CANCER	LAMA2 LAMA5 LAMA1	2.90e-04	84	22	3	M3228
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	LAMA2 LAMA5 LAMA1	2.90e-04	84	22	3	M7098
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_LGR_RSPO	LGR5 FZD5	3.91e-04	19	22	2	M47833
Pathway	WP_SMALL_CELL_LUNG_CANCER	LAMA2 LAMA5 LAMA1	4.29e-04	96	22	3	M39834
Pathway	REACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION	LGR5 FZD5	4.34e-04	20	22	2	MM15155
Pathway	REACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION	LGR5 FZD5	4.80e-04	21	22	2	M27401
Pathway	WP_PLEURAL_MESOTHELIOMA	LAMA2 LAMA5 BTC FZD5 LAMA1	4.86e-04	439	22	5	M42563
Pathway	WP_CANCER_PATHWAYS	LAMA2 LAMA5 FZD5 JAG1 LAMA1	9.35e-04	507	22	5	M48302
Pathway	BIOCARTA_AGR_PATHWAY	LAMA2 LAMA1	1.05e-03	31	22	2	MM1343
Pathway	KEGG_PATHWAYS_IN_CANCER	LAMA2 LAMA5 FZD5 LAMA1	1.46e-03	325	22	4	M12868
Pathway	REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT	KMT2D LGR5 FZD5	1.82e-03	158	22	3	MM14791
Pathway	WP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER	GDF15 FZD5 JAG1	1.92e-03	161	22	3	M39770
Pathway	WP_FOCAL_ADHESION	LAMA2 LAMA5 LAMA1	2.94e-03	187	22	3	MM15913
Pathway	PID_TAP63_PATHWAY	GDF15 JAG1	3.17e-03	54	22	2	M256
Pathway	KEGG_FOCAL_ADHESION	LAMA2 LAMA5 LAMA1	3.50e-03	199	22	3	M7253
Pathway	WP_FOCAL_ADHESION	LAMA2 LAMA5 LAMA1	3.50e-03	199	22	3	M39402
Pubmed	The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.	LAMA2 LAMA5 LGR5 LAMA1	4.19e-10	13	32	4	36350252
Pubmed	Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach.	LAMA2 LAMA5 LAMA1	7.07e-09	5	32	3	11969289
Pubmed	Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.	LAMA2 LAMA5 LAMA1	7.07e-09	5	32	3	11829758
Pubmed	Differential expression of five laminin alpha (1-5) chains in developing and adult mouse kidney.	LAMA2 LAMA5 LAMA1	7.07e-09	5	32	3	9415429
Pubmed	Differential expression of laminin alpha chains during murine tooth development.	LAMA2 LAMA5 LAMA1	7.07e-09	5	32	3	9389447
Pubmed	HIV-protein-mediated alterations in T cell interactions with the extracellular matrix proteins and endothelium.	LAMA2 LAMA5 LAMA1	1.41e-08	6	32	3	9597096
Pubmed	Laminin isoforms in fetal and adult human adrenal cortex.	LAMA2 LAMA5 LAMA1	2.47e-08	7	32	3	14557481
Pubmed	Abscence of laminin alpha1 chain in the skeletal muscle of dystrophic dy/dy mice.	LAMA2 LAMA5 LAMA1	2.47e-08	7	32	3	9390664
Pubmed	Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.	LAMA2 LAMA5 LAMA1	3.95e-08	8	32	3	9852162
Pubmed	Laminin-1 promotes differentiation of fetal mouse pancreatic beta-cells.	LAMA2 LAMA5 LAMA1	3.95e-08	8	32	3	10102687
Pubmed	Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.	LAMA2 LAMA5 LAMA1	3.95e-08	8	32	3	8872465
Pubmed	Expression of laminin alpha1, alpha2, alpha4, and alpha5 chains, fibronectin, and tenascin-C in skeletal muscle of dystrophic 129ReJ dy/dy mice.	LAMA2 LAMA5 LAMA1	5.92e-08	9	32	3	9882526
Pubmed	Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.	LAMA2 LAMA5 LAMA1	8.45e-08	10	32	3	9034910
Pubmed	Integrin-laminin interactions controlling neurite outgrowth from adult DRG neurons in vitro.	LAMA2 LAMA5 LAMA1	8.45e-08	10	32	3	18590826
Pubmed	Trophoblast-specific expression and function of the integrin alpha 7 subunit in the peri-implantation mouse embryo.	LAMA2 LAMA5 LAMA1	8.45e-08	10	32	3	11784026
Pubmed	Primary cellular meningeal defects cause neocortical dysplasia and dyslamination.	LAMA2 LAMA5 LAMA1	8.45e-08	10	32	3	20976766
Pubmed	Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung.	LAMA2 LAMA5 LAMA1	1.16e-07	11	32	3	12051813
Pubmed	Regional differences in the expression of laminin isoforms during mouse neural tube development.	LAMA2 LAMA5 LAMA1	1.16e-07	11	32	3	21524702
Pubmed	Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.	LAMA2 LAMA5 LAMA1	1.16e-07	11	32	3	23472759
Pubmed	Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis.	LAMA2 LAMA5 LAMA1	1.55e-07	12	32	3	11381080
Pubmed	Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.	LAMA2 LAMA5 LAMA1	1.55e-07	12	32	3	16750824
Pubmed	Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.	LAMA2 LAMA5 LAMA1	1.55e-07	12	32	3	9396756
Pubmed	Fukutin-related protein alters the deposition of laminin in the eye and brain.	LAMA2 LAMA5 LAMA1	2.01e-07	13	32	3	21900571
Pubmed	The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform.	LAMA2 LAMA5 LAMA1	2.56e-07	14	32	3	9151674
Pubmed	Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.	LAMA2 LAMA5 LAMA1	3.19e-07	15	32	3	10625553
Pubmed	Laminin alpha5 chain is required for intestinal smooth muscle development.	LAMA2 LAMA5 LAMA1	3.19e-07	15	32	3	12921739
Pubmed	Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.	LAMA2 LAMA5 LAMA1	3.19e-07	15	32	3	9264260
Pubmed	Basement membrane composition in the early mouse embryo day 7.	LAMA2 LAMA5 LAMA1	3.19e-07	15	32	3	15895400
Pubmed	Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.	LAMA2 LAMA5 LAMA1	3.93e-07	16	32	3	17601529
Pubmed	Laminin α1 is essential for mouse cerebellar development.	LAMA2 LAMA5 LAMA1	4.77e-07	17	32	3	21983115
Pubmed	Beta1-integrins are critical for cerebellar granule cell precursor proliferation.	LAMA2 LAMA5 LAMA1	4.77e-07	17	32	3	15056720
Pubmed	Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.	LAMA2 LAMA5 LAMA1	5.72e-07	18	32	3	11311202
Pubmed	A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.	LAMA2 LAMA5 LAMA1	5.72e-07	18	32	3	14730302
Pubmed	Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.	LAMA2 LAMA5 LAMA1	7.98e-07	20	32	3	22911573
Pubmed	Transgenic overexpression of laminin alpha1 chain in laminin alpha2 chain-deficient mice rescues the disease throughout the lifespan.	LAMA2 LAMA1	8.20e-07	2	32	2	20544910
Pubmed	Presynaptic congenital myasthenic syndrome with a homozygous sequence variant in LAMA5 combines myopia, facial tics, and failure of neuromuscular transmission.	LAMA5 LAMA1	8.20e-07	2	32	2	28544784
Pubmed	Conserved neuron promoting activity in Drosophila and vertebrate laminin alpha1.	LAMA2 LAMA1	8.20e-07	2	32	2	8663504
Pubmed	Laminin α1 reduces muscular dystrophy in dy2J mice.	LAMA2 LAMA1	8.20e-07	2	32	2	29544677
Pubmed	The expression pattern of laminin isoforms in Hirschsprung disease reveals a distal peripheral nerve differentiation.	LAMA2 LAMA5	8.20e-07	2	32	2	16226104
Pubmed	Laminin 2 attachment selects myofibroblasts from fetal mouse lung.	LAMA2 LAMA1	8.20e-07	2	32	2	9728058
Pubmed	The laminin response in inflammatory bowel disease: protection or malignancy?	LAMA5 LAMA1	8.20e-07	2	32	2	25347196
Pubmed	Distinct roles for laminin globular domains in laminin alpha1 chain mediated rescue of murine laminin alpha2 chain deficiency.	LAMA2 LAMA1	8.20e-07	2	32	2	20657839
Pubmed	[Correlation between ultrastructural changes of glomerular basement membrane and abnormal distribution of laminins in patients with Alport's syndrome].	LAMA5 LAMA1	8.20e-07	2	32	2	20019771
Pubmed	Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.	LAMA2 LAMA5 LAMA1	1.08e-06	22	32	3	28334989
Pubmed	Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis.	LAMA2 LAMA5 LAMA1	1.60e-06	25	32	3	19373938
Pubmed	Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.	LAMA2 LAMA5 LAMA1	1.81e-06	26	32	3	24742657
Pubmed	Adamts18 modulates the development of the aortic arch and common carotid artery.	LAMA5 JAG1 LAMA1	1.81e-06	26	32	3	34189436
Pubmed	Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5(+) stem cells.	LGR5 FZD5	2.46e-06	3	32	2	25892522
Pubmed	Laminin α2, α4, and α5 Chains Positively Regulate Migration and Survival of Oligodendrocyte Precursor Cells.	LAMA2 LAMA5	2.46e-06	3	32	2	31882770
Pubmed	Expression of laminin alpha 1, alpha 5 and beta 2 chains during embryogenesis of the kidney and vasculature.	LAMA5 LAMA1	2.46e-06	3	32	2	9049978
Pubmed	Fibulin-2 binds to the short arms of laminin-5 and laminin-1 via conserved amino acid sequences.	LAMA5 LAMA1	2.46e-06	3	32	2	9006922
Pubmed	Expression of laminin chains during myogenic differentiation.	LAMA2 LAMA1	2.46e-06	3	32	2	7510707
Pubmed	Dystroglycan is a binding protein of laminin and merosin in peripheral nerve.	LAMA2 LAMA1	2.46e-06	3	32	2	7925941
Pubmed	Laminin isoform-specific promotion of adhesion and migration of human bone marrow progenitor cells.	LAMA5 LAMA1	2.46e-06	3	32	2	12393739
Pubmed	Laminin alpha1 chain mediated reduction of laminin alpha2 chain deficient muscular dystrophy involves integrin alpha7beta1 and dystroglycan.	LAMA2 LAMA1	2.46e-06	3	32	2	16504180
Pubmed	α1- and α5-containing laminins regulate the development of bile ducts via β1 integrin signals.	LAMA5 LAMA1	2.46e-06	3	32	2	22761447
Pubmed	Developmental expression and cellular origin of the laminin alpha2, alpha4, and alpha5 chains in the intestine.	LAMA2 LAMA5	2.46e-06	3	32	2	10364433
Pubmed	Differential expression of laminin isoforms and alpha 6-beta 4 integrin subunits in the developing human and mouse intestine.	LAMA2 LAMA1	2.46e-06	3	32	2	7803849
Pubmed	Heterologously overexpressed, affinity-purified human meprin alpha is functionally active and cleaves components of the basement membrane in vitro.	LAMA5 LAMA1	2.46e-06	3	32	2	10620696
Pubmed	Brain alpha-dystroglycan displays unique glycoepitopes and preferential binding to laminin-10/11.	LAMA2 LAMA1	2.46e-06	3	32	2	16709410
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	LAMA2 LAMA5 LAMA1	2.54e-06	29	32	3	22613833
Pubmed	Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation.	SP9 ASTN2 FZD5	3.12e-06	31	32	3	36476860
Pubmed	Large-scale identification of genes implicated in kidney glomerulus development and function.	LAMA2 LAMA5 LAMA1	4.15e-06	34	32	3	16498405
Pubmed	Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.	LGR5 FZD5	4.92e-06	4	32	2	22895187
Pubmed	Expression of laminin chains by central neurons: analysis with gene and protein trapping techniques.	LAMA5 LAMA1	4.92e-06	4	32	2	12820173
Pubmed	Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits.	LAMA2 LAMA1	4.92e-06	4	32	2	2099832
Pubmed	Laminin compensation in collagen alpha3(IV) knockout (Alport) glomeruli contributes to permeability defects.	LAMA5 LAMA1	4.92e-06	4	32	2	17699809
Pubmed	Laminin-1 reexpression in Alport mouse glomerular basement membranes.	LAMA5 LAMA1	4.92e-06	4	32	2	12631063
Pubmed	Developmental regulation of the laminin alpha5 chain suggests a role in epithelial and endothelial cell maturation.	LAMA5 LAMA1	4.92e-06	4	32	2	9299121
Pubmed	Molecular recognition by LARGE is essential for expression of functional dystroglycan.	LAMA2 LAMA1	4.92e-06	4	32	2	15210115
Pubmed	Laminin alpha 1, alpha 2, alpha 4 and beta 1 chain mRNA expression in mouse embryonic, neonatal, and adult hearts.	LAMA2 LAMA1	4.92e-06	4	32	2	9201115
Pubmed	An agrin minigene rescues dystrophic symptoms in a mouse model for congenital muscular dystrophy.	LAMA2 LAMA5	4.92e-06	4	32	2	11565031
Pubmed	Organisation of extracellular matrix proteins laminin and agrin in pericapillary basal laminae in mouse brain.	LAMA2 LAMA1	4.92e-06	4	32	2	32072250
Pubmed	Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.	LAMA2 LAMA5 LAMA1	6.83e-06	40	32	3	27068110
Pubmed	Tissue-specific expression of the human laminin alpha5-chain, and mapping of the gene to human chromosome 20q13.2-13.3 and to distal mouse chromosome 2 near the locus for the ragged (Ra) mutation.	LAMA2 LAMA5	8.19e-06	5	32	2	9271224
Pubmed	Sp8 and Sp9, two closely related buttonhead-like transcription factors, regulate Fgf8 expression and limb outgrowth in vertebrate embryos.	SP9 SP8	8.19e-06	5	32	2	15358670
Pubmed	Posttranslational modifications and beta/gamma chain associations of human laminin alpha1 and laminin alpha5 chains: purification of laminin-3 from placenta.	LAMA5 LAMA1	8.19e-06	5	32	2	10964500
Pubmed	Laminin alpha 2 chain (M chain) is found within the pathway of avian and murine retinal projections.	LAMA2 LAMA1	8.19e-06	5	32	2	8613743
Pubmed	Laminin gamma2 expression is developmentally regulated during murine tooth morphogenesis and is intense in ameloblasts.	LAMA5 LAMA1	8.19e-06	5	32	2	9719032
Pubmed	Laminin-10 is crucial for hair morphogenesis.	LAMA5 LAMA1	8.19e-06	5	32	2	12743034
Pubmed	Expression of laminin isoforms in mouse myogenic cells in vitro and in vivo.	LAMA2 LAMA1	8.19e-06	5	32	2	8719886
Pubmed	Cross-linking of laminin-nidogen complexes by tissue transglutaminase. A novel mechanism for basement membrane stabilization.	LAMA2 LAMA1	1.23e-05	6	32	2	1678389
Pubmed	Structural elucidation of full-length nidogen and the laminin-nidogen complex in solution.	LAMA2 LAMA1	1.23e-05	6	32	2	23948589
Pubmed	Essential role of alpha 6 integrins in cortical and retinal lamination.	LAMA2 LAMA1	1.23e-05	6	32	2	9742403
Pubmed	A synaptic nidogen: developmental regulation and role of nidogen-2 at the neuromuscular junction.	LAMA2 LAMA5	1.23e-05	6	32	2	18817539
Pubmed	Entactin: structure and function.	LAMA2 LAMA1	1.23e-05	6	32	2	2119632
Pubmed	Laminin is the ECM niche for trophoblast stem cells.	LAMA5 LAMA1	1.23e-05	6	32	2	31937556
Pubmed	Laminin alpha1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly.	LAMA5 LAMA1	1.23e-05	6	32	2	15668394
Pubmed	Indispensable role of Notch ligand-dependent signaling in the proliferation and stem cell niche maintenance of APC-deficient intestinal tumors.	LGR5 JAG1	1.23e-05	6	32	2	27939883
Pubmed	Absence of post-phosphoryl modification in dystroglycanopathy mouse models and wild-type tissues expressing non-laminin binding form of α-dystroglycan.	LAMA2 LAMA1	1.23e-05	6	32	2	22270369
Pubmed	Impaired primary mouse myotube formation on crosslinked type I collagen films is enhanced by laminin and entactin.	LAMA2 LAMA1	1.23e-05	6	32	2	26555376
Pubmed	Effect of basement membrane entactin on epidermal cell attachment and growth.	LAMA2 LAMA1	1.23e-05	6	32	2	3794389
Pubmed	Laminin regulates PDGFRβ(+) cell stemness and muscle development.	LAMA2 LAMA1	1.23e-05	6	32	2	27138650
Pubmed	Laminin-nidogen complex. Extraction with chelating agents and structural characterization.	LAMA2 LAMA1	1.23e-05	6	32	2	3109910
Pubmed	Sox9 plays multiple roles in the lung epithelium during branching morphogenesis.	LAMA2 LAMA5 LAMA1	1.35e-05	50	32	3	24191021
Pubmed	Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling.	LGR5 FZD5 JAG1	1.35e-05	50	32	3	27510977
Pubmed	Dynamic expression of Lgr5, a Wnt target gene, in the developing and mature mouse cochlea.	LGR5 JAG1	1.72e-05	7	32	2	21472479
Pubmed	Distinct alpha 7A beta 1 and alpha 7B beta 1 integrin expression patterns during mouse development: alpha 7A is restricted to skeletal muscle but alpha 7B is expressed in striated muscle, vasculature, and nervous system.	LAMA2 LAMA1	1.72e-05	7	32	2	8950511
Pubmed	Beta1 integrins are required for the invasion of the caecum and proximal hindgut by enteric neural crest cells.	LAMA5 LAMA1	2.29e-05	8	32	2	19633172
Pubmed	Mouse AMACO, a kidney and skin basement membrane associated molecule that mediates RGD-dependent cell attachment.	LAMA5 LAMA1	2.29e-05	8	32	2	19651211
Cytoband	Ensembl 112 genes in cytogenetic band chr11q14	TENM4 TMEM135	5.32e-03	156	32	2	chr11q14
GeneFamily	Laminin subunits	LAMA2 LAMA5 LAMA1	3.42e-07	12	22	3	626
GeneFamily	Zinc fingers C2H2-type\|Sp transcription factors	SP9 SP8	5.06e-05	9	22	2	755
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	PLEKHF2 FGD3	6.43e-04	31	22	2	81
GeneFamily	PHD finger proteins	KMT2D NFX1	5.31e-03	90	22	2	88
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF202 SP9 SP8 ZNF425	1.02e-02	718	22	4	28
GeneFamily	Fibronectin type III domain containing	ASTN2 TRIM36	1.60e-02	160	22	2	555
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHF2 FGD3	2.57e-02	206	22	2	682
Coexpression	NABA_BASEMENT_MEMBRANES	LAMA2 LAMA5 LAMA1	1.58e-05	40	32	3	M5887
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	SP9 SP8 TENM4 TRIM36 LGR5 FZD5 JAG1 LAMA1	3.38e-05	1074	32	8	M1941
ToppCell	3'-Adult-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TENM4 LGR5 GDF15 FZD5	6.22e-06	168	32	4	b08458164d270d625b8ee390122d1c2ce8c653db
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ASTN2 TENM4 LGR5 LAMA1	7.81e-06	178	32	4	4df6218b20c2f076c22346d23260964cc0d73e65
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_3\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	SP9 SP8 TRIM36 FGD3	1.16e-05	197	32	4	d77bc37a77546a1f0a508486a38a45e571e4645b
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA5 TENM4 GDF15 JAG1	1.19e-05	198	32	4	19d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Vip_Itih5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMA5 SP8 TRIM36	7.84e-05	116	32	3	605bd4fdf547cc41783e99cd78425760ef6461ef
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA5 LINC01548 GDF15	2.43e-04	170	32	3	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_ventral_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	SP9 SP8 FGD3	2.43e-04	170	32	3	73601c873b177d5d134618d8e228c51381119f7d
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Chat_Htr1f\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMA5 SP9 SP8	2.47e-04	171	32	3	f9ae7964a3740f559431125c17c660549798cccc
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ASTN2 TENM4 LAMA1	2.51e-04	172	32	3	0c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 ZNF202 ASTN2	2.51e-04	172	32	3	de4961f4037c439d3e0ec706a257b0ec17f4d5be
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ASTN2 TENM4 LAMA1	2.51e-04	172	32	3	eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SP8 LGR5 GDF15	2.60e-04	174	32	3	e7cca4b6a3935fad61cf2a3d9984ab1ffa1a9447
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-Alox5+_Lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NMUR1 GDF15 FZD5	2.60e-04	174	32	3	a8bd1fa08bf061a627529a38e5a23a68b6d80697
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SP8 LGR5 GDF15	2.60e-04	174	32	3	ad5b56f0ace6455c033834b931ec870cc0dc9290
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NMUR1 GDF15 FZD5	2.60e-04	174	32	3	7f8f6a15a823809effd37c1a5b09ef19b6d67755
ToppCell	wk_15-18-Epithelial-Distal_epithelial-type_I_pneumocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	LAMA5 GDF15 FZD5	2.60e-04	174	32	3	2cd6638b361ca05ab83d09ce657194aed97873b7
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Chat_Htr1f\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMA5 SP9 SP8	2.60e-04	174	32	3	a5f2a4e3b25e6084bd7003a53da86a44f6fcf294
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TENM4 LGR5 LAMA1	2.64e-04	175	32	3	e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NMUR1 TRIM36 EPHX3	2.64e-04	175	32	3	fb91a45763e4c48d993094a13088ffc19f1e2574
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NMUR1 TRIM36 EPHX3	2.64e-04	175	32	3	2a53d4f140d5ab096efe8118d8aa351db7838b49
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	EPHX3 BTC FAM229A	2.73e-04	177	32	3	ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	EPHX3 BTC FAM229A	2.73e-04	177	32	3	d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SP9 SP8 TRIM36	2.78e-04	178	32	3	08b4a497aca0aeabf4f6a8a55c05b56417b69e78
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TENM4 LGR5 LAMA1	2.78e-04	178	32	3	dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 EPHX3 LAMA1	2.82e-04	179	32	3	f99500c4a590e5152ded5862690f7fa614d64a80
ToppCell	facs-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 NMUR1 EPHX3	2.82e-04	179	32	3	7078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 EPHX3 LAMA1	2.82e-04	179	32	3	7d61466181ab73088de3ec8a129d7cfa8cac7ecc
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TENM4 LGR5 LAMA1	2.82e-04	179	32	3	d0fa700648db8ce76a8aa689879a25048299fa40
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 EPHX3 LAMA1	2.82e-04	179	32	3	6c98ce32cb55cf9cee557449e41b23bdb22f5efd
ToppCell	facs-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 NMUR1 EPHX3	2.82e-04	179	32	3	d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TENM4 LGR5 LAMA1	2.82e-04	179	32	3	2e49b215b71438400aebb483f2c2c08d5e956961
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SP9 SP8 TRIM36	2.87e-04	180	32	3	392bc71a69653ba12de31bed4e9357f181094641
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SP9 SP8 TRIM36	2.91e-04	181	32	3	8fd64404e57c22c204d835fc5626f73554257b19
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SP8 NMUR1 TRIM36	2.91e-04	181	32	3	03a303cd2f366f09c18b118bbba6f5e3f95ad56c
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 SP9 SP8	2.96e-04	182	32	3	904804813849b7f7f716ba1554d33b07bc0a701e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 SP9 SP8	2.96e-04	182	32	3	5d8b7fe18286e27f0f50c5d2d9be56850e2cb8f4
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-SST-MGE1-3\|World / Primary Cells by Cluster	SP9 SP8 FGD3	3.06e-04	184	32	3	907ba412166bcb0526c5be0b06a76b6bd37c5a35
ToppCell	facs-Heart-RA-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LGR5 EPHX3 JAG1	3.11e-04	185	32	3	c4ef8d9f8b9769e887daac4efd9dc05738b28ae2
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LGR5 GDF15 LAMA1	3.11e-04	185	32	3	6da9a06e1514d5d5f47359a14637f02539846096
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KMT2D LGR5 ZNF425	3.11e-04	185	32	3	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	facs-Heart-RA-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LGR5 EPHX3 JAG1	3.11e-04	185	32	3	10ddf38d908525b4258f9d2da8be4c56ebc08ff4
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LGR5 GDF15 LAMA1	3.11e-04	185	32	3	4a188e2566a75d1b4f3c879a8c241c277c4b451c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ASTN2 TENM4 LAMA1	3.11e-04	185	32	3	03f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ASTN2 TENM4 LAMA1	3.16e-04	186	32	3	1850583d23903d08226aeb0edb3e07b0994330e4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ASTN2 TENM4 LAMA1	3.16e-04	186	32	3	4dafc215c42e7949f932a3627359c107943b5d6b
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LAMA5 GDF15 FZD5	3.21e-04	187	32	3	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	LAMA2 TENM4 FGD3	3.21e-04	187	32	3	a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-NK_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NMUR1 ST3GAL1 FGD3	3.31e-04	189	32	3	5a9c3c61998efc40a5d2042e0f568b52103734a9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ASTN2 TENM4 LAMA1	3.36e-04	190	32	3	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ASTN2 TENM4 LAMA1	3.36e-04	190	32	3	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-RG-RG-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SP9 SP8 TRIM36	3.36e-04	190	32	3	7a560d046aeff979cdf543c519e4e51280f5e232
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	SP9 SP8 FGD3	3.36e-04	190	32	3	842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCell	COVID-19-kidney-TAL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ASTN2 TENM4 LAMA1	3.41e-04	191	32	3	fe55475ce0666ab5122447a813dc2369e24947b8
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ASTN2 TENM4 LAMA1	3.41e-04	191	32	3	9032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron\|World / Primary Cells by Cluster	SP9 SP8 FGD3	3.41e-04	191	32	3	4dd9c8117c4499ed9bde127baf2598603a82080d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ASTN2 TENM4 LAMA1	3.41e-04	191	32	3	2fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_2\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	SP9 FZD5 FGD3	3.41e-04	191	32	3	509d17d8ee0d028757ce0f2c9b97e5875f06f0ab
ToppCell	COVID-19-kidney-Mito-rich_Distal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ASTN2 TENM4 LAMA1	3.41e-04	191	32	3	0965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ASTN2 TENM4 LAMA1	3.41e-04	191	32	3	5717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-SST-MGE1\|World / Primary Cells by Cluster	SP9 SP8 FGD3	3.46e-04	192	32	3	bcc499f4c7ba2898ecd9c47bf68c92ed359b81ba
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX3 GDF15 JAG1	3.57e-04	194	32	3	3bff2e4eb16719ab7419b2f94c9c6e7302aa6629
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 ASTN2 LAMA1	3.57e-04	194	32	3	415801a3dfacf05f2b603fb424df3d045190a812
ToppCell	18-Airway-Epithelial-Bud_tip_adjacent\|Airway / Age, Tissue, Lineage and Cell class	LAMA5 GDF15 FZD5	3.57e-04	194	32	3	b45f1e80074a19245bc5dc4b3a583419a1904404
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 ASTN2 LAMA1	3.57e-04	194	32	3	256cb33ec90328f2704921fb0fe0fd9812e138b0
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX3 GDF15 JAG1	3.57e-04	194	32	3	fdaf61cbe7f77ff5358d150b38adb1fe3778e961
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 ASTN2 LAMA1	3.57e-04	194	32	3	7942bc83c1bdca687795b91aa232824d603f9b09
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SP8 TENM4 GDF15	3.62e-04	195	32	3	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	wk_20-22-Epithelial-Distal_epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	LAMA5 GDF15 FZD5	3.68e-04	196	32	3	cd507ee2baf4f52d6498811b3510d3164b56311f
ToppCell	wk_20-22-Epithelial-Distal_epithelial-type_I_pneumocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	LAMA5 GDF15 FZD5	3.68e-04	196	32	3	e24a7aaf41793abba66c1189d933ca05b14c1af9
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 TENM4 LGR5	3.73e-04	197	32	3	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SP8 GDF15 LAMA1	3.73e-04	197	32	3	5027787ab3ce60e1ddcb99e3a01f40bb07b05804
ToppCell	5'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SP8 GDF15 LAMA1	3.73e-04	197	32	3	6ee6939c492bedf1f96a715da7a26a4c55a7c36f
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRIM36 BTC JAG1	3.73e-04	197	32	3	15a08b04acb1cb7e84aeb072c650ce07374181f5
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_3\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	SP9 SP8 FGD3	3.73e-04	197	32	3	62c0682eb32a41c58d31ae33b23e7d61ce5a6abb
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_2\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	SP9 SP8 FGD3	3.79e-04	198	32	3	b73b9feb82997b654718aa27f33ca7b454214802
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA5 TENM4 JAG1	3.79e-04	198	32	3	5374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GDF15 FZD5 LAMA1	3.85e-04	199	32	3	9d24223b571fba202455c5bd49bd79530abf09c0
ToppCell	Biopsy_IPF-Epithelial-Transitional_AT2\|Biopsy_IPF / Sample group, Lineage and Cell type	LAMA5 GDF15 FZD5	3.85e-04	199	32	3	83ff8b7e472d1212324c05cc719b746d19e5e23b
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1--L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SP9 ASTN2 LGR5	3.90e-04	200	32	3	4a426ef88376d8bb2b9dc50aa06e7b9fc50ecc9c
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-STK32A\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ASTN2 LGR5 FGD3	3.90e-04	200	32	3	8d51b4f7b7002ee51401ebe5eaca1e8f04bfadd5
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-STK32A-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ASTN2 LGR5 FGD3	3.90e-04	200	32	3	6a44439e4a7ce3627271375b04cfcfb9467218f4
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-STK32A--L4-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ASTN2 LGR5 FGD3	3.90e-04	200	32	3	cb1f4b0d66da5b0466ff17b29e7034d451d93e4f
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Suprabasal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF425 EPHX3 GDF15	3.90e-04	200	32	3	924eacea513dde8e3bd805a335bc4285647b800d
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SP9 ASTN2 LGR5	3.90e-04	200	32	3	fbeee1c16ac0a7fe28d90491c8b079f21ce80bdc
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SP9 ASTN2 LGR5	3.90e-04	200	32	3	c6eda342ea0cb37d71d89dbb8d11e819e0745172
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 TENM4 LGR5	3.90e-04	200	32	3	fb53be20392a8309a7393774c774a1b1aec6e676
Drug	AC1L1G72	LAMA2 LAMA5 LAMA1	4.13e-07	11	32	3	CID000003553
Drug	dysprosium	LAMA2 LAMA5 NMUR1 LAMA1	3.45e-06	74	32	4	CID000023912
Drug	AC1L1B58	LAMA2 LAMA5 LAMA1	8.99e-06	29	32	3	CID000001288
Drug	chromotropic acid	BTC JAG1	1.91e-05	5	32	2	CID000067220
Drug	Calcort	LAMA2 LAMA5 LAMA1	2.06e-05	38	32	3	CID000026709
Disease	Schizophrenia	LAMA2 ASTN2 ST3GAL1 TENM4 BTC JAG1 LAMA1	2.34e-05	883	30	7	C0036341
Disease	Nonorganic psychosis	SP8 ST3GAL1 TENM4	4.75e-05	69	30	3	C0349204
Disease	cortical thickness	LAMA2 SP8 ASTN2 LINC01548 TRIM36 JAG1 LAMA1	1.01e-04	1113	30	7	EFO_0004840
Disease	Psychotic Disorders	SP8 ST3GAL1 TENM4	1.48e-04	101	30	3	C0033975
Disease	refractive error, self reported educational attainment	LAMA2 BTC	5.49e-04	34	30	2	EFO_0004784, MONDO_0004892
Disease	metastasis measurement, disease progression measurement	SP9 ASTN2	5.49e-04	34	30	2	EFO_0007675, EFO_0008336
Disease	hippocampal CA3 volume	ASTN2 JAG1	6.16e-04	36	30	2	EFO_0009395
Disease	heel bone mineral density, urate measurement	ASTN2 ST3GAL1 TMEM135	8.29e-04	182	30	3	EFO_0004531, EFO_0009270
Disease	idiopathic osteonecrosis of the femoral head	SPRY3 ASTN2	1.28e-03	52	30	2	EFO_1001930
Disease	Bipolar Disorder	SP8 ASTN2 ST3GAL1 TENM4	1.32e-03	477	30	4	C0005586
Disease	interleukin 12 measurement	TENM4 NFX1	1.33e-03	53	30	2	EFO_0004753
Disease	adverse effect, response to xenobiotic stimulus	ASTN2 LAMA1	1.65e-03	59	30	2	EFO_0009658, GO_0009410
Disease	response to antipsychotic drug	ZNF202 TENM4	1.71e-03	60	30	2	GO_0097332
Disease	Corneal astigmatism	NMUR1 TMEM135	2.79e-03	77	30	2	EFO_1002040
Disease	Glioblastoma	JAG1 TMEM135	2.93e-03	79	30	2	C0017636
Disease	Giant Cell Glioblastoma	JAG1 TMEM135	3.31e-03	84	30	2	C0334588
Disease	migraine disorder, Headache	ASTN2 DGKZ	3.46e-03	86	30	2	HP_0002315, MONDO_0005277
Disease	diastolic blood pressure, systolic blood pressure	TENM4 OVOL3 EPHX3 JAG1	4.52e-03	670	30	4	EFO_0006335, EFO_0006336
Disease	malaria	ASTN2 TRIM36	4.83e-03	102	30	2	EFO_0001068

Protein segments in the cluster

Peptide	Gene	Start	Entry
LRRCPGCHCLTLLHV	FAM229A	96	H3BQW9
GRCPSTCHLCRRPGK	ASTN2	981	O75129
SPCHRSCFCGELKRG	LINC01548	56	A6NM66
LCLGACCHRLRPRHS	NMUR1	371	Q9HB89
LGCRNHKCPSVCHRG	NFXL1	501	Q6ZNB6
CPLICGRKLRCGLHR	NFX1	711	Q12986
GRKLRCGLHRCEEPC	NFX1	716	Q12986
KHARRGLAPGSCHCK	LAMA2	431	P24043
DHCPLGPGRCCRLHT	GDF15	201	Q99988
RRHHCKLCGAVICGK	FGD3	551	Q5JSP0
CRGCLRHTTGPRCEI	LAMA5	1991	O15230
HSPVRRHLCRCCGKG	OVOL3	116	O00110
RCCCRPRRGHKSGGA	FZD5	536	Q13467
CIALTHVLCRPRRGC	EPHX3	41	Q9H6B9
HRRRQDGKCRHCGKG	DGKZ	176	Q13574
IGVCTCCHPLRKRRK	BTC	136	P35070
RSGVLLRGCPTHCHC	LGR5	26	O75473
RRHHCRKCGFVVCGP	PLEKHF2	171	Q9H8W4
RAICRQGCSPKHGSC	JAG1	231	P78504
LCRRPVCHLCKLGGN	TRIM36	226	Q9NQ86
CVPGVAGKRCDRCAH	LAMA1	971	P25391
HRPCTCTHCIGQRKL	ST3GAL1	56	Q11201
LRRKGLHSCHIPGCG	SP9	326	P0CG40
RRPGCRCKRHTNTVC	SPRY3	256	O43610
RRKGLHSCHIPGCGK	SP8	351	Q8IXZ3
DSICKHGPRHRCCKH	TMEM135	231	Q86UB9
HPRCAEHGTCRDGKC	TENM4	761	Q6N022
ACRHGDRCSRLHNKP	U2AF1	26	Q01081
KHLCLHRGERPFCCG	ZNF425	291	Q6IV72
AKHLRGHASVRPCRC	ZNF202	581	O95125
GHCDPRRCTGRKLAR	TSR3	66	Q9UJK0
RCSHCTRLGASIPCR	KMT2D	171	O14686
GHCDPLTKRCICSHL	KIAA0319	921	Q5VV43