Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesssensory perception

SCN10A PRDM12 LAMB2 TAS2R20 OR12D1 CALHM3 POMK OR10X1 OR52B6 OR5D13 OR5B17 ITPR3

4.47e-0610724812GO:0007600
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

TAS2R20 OR12D1 CALHM3 OR10X1 OR52B6 OR5D13 OR5B17 ITPR3

3.45e-05547488GO:0007606
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

SCN10A PRDM12 TAS2R20 OR12D1 OR10X1 OR52B6 OR5D13 OR5B17

5.34e-05582488GO:0050906
GeneOntologyCellularComponentclathrin complex

SCN10A VPS41

1.76e-049472GO:0071439
MousePhenoabnormal gustatory system physiology

CALHM3 SCN7A ITPR3

1.63e-0522323MP:0001985
Domain-

ZNF521 PRDM12 ZNF630 ZNF776 IKZF2 ZBTB16 ZNF699 ZNF827 IKZF4

4.15e-056794793.30.160.60
Domainzf-C2H2

ZNF521 PRDM12 ZNF630 ZNF776 IKZF2 ZBTB16 ZNF699 ZNF827 IKZF4

4.87e-05693479PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF521 PRDM12 ZNF630 ZNF776 IKZF2 ZBTB16 ZNF699 ZNF827 IKZF4

4.92e-05694479IPR013087
DomainZINC_FINGER_C2H2_2

ZNF521 PRDM12 ZNF630 ZNF776 IKZF2 ZBTB16 ZNF699 ZNF827 IKZF4

1.15e-04775479PS50157
DomainZINC_FINGER_C2H2_1

ZNF521 PRDM12 ZNF630 ZNF776 IKZF2 ZBTB16 ZNF699 ZNF827 IKZF4

1.17e-04777479PS00028
DomainZnf_C2H2-like

ZNF521 PRDM12 ZNF630 ZNF776 IKZF2 ZBTB16 ZNF699 ZNF827 IKZF4

1.41e-04796479IPR015880
DomainZnf_C2H2

ZNF521 PRDM12 ZNF630 ZNF776 IKZF2 ZBTB16 ZNF699 ZNF827 IKZF4

1.53e-04805479IPR007087
DomainZnF_C2H2

ZNF521 PRDM12 ZNF630 ZNF776 IKZF2 ZBTB16 ZNF699 ZNF827 IKZF4

1.57e-04808479SM00355
DomainDynein_heavy_dom-1

DNAH2 DNAH8

1.72e-048472IPR013594
DomainDHC_N1

DNAH2 DNAH8

1.72e-048472PF08385
DomainNa_channel_asu

SCN10A SCN7A

2.75e-0410472IPR001696
DomainNa_trans_assoc

SCN10A SCN7A

2.75e-0410472IPR010526
DomainNa_trans_assoc

SCN10A SCN7A

2.75e-0410472PF06512
DomainATPase_dyneun-rel_AAA

DNAH2 DNAH8

5.53e-0414472IPR011704
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH8

5.53e-0414472IPR024317
DomainDynein_HC_stalk

DNAH2 DNAH8

5.53e-0414472IPR024743
DomainDynein_heavy_dom-2

DNAH2 DNAH8

5.53e-0414472IPR013602
DomainDHC_N2

DNAH2 DNAH8

5.53e-0414472PF08393
DomainMT

DNAH2 DNAH8

5.53e-0414472PF12777
DomainAAA_8

DNAH2 DNAH8

5.53e-0414472PF12780
DomainAAA_5

DNAH2 DNAH8

5.53e-0414472PF07728
DomainDHC_fam

DNAH2 DNAH8

6.37e-0415472IPR026983
DomainDynein_heavy_dom

DNAH2 DNAH8

6.37e-0415472IPR004273
DomainDynein_heavy

DNAH2 DNAH8

6.37e-0415472PF03028
DomainIQ_motif_EF-hand-BS

SCN10A MYO1B SCN7A

1.51e-0390473IPR000048
DomainIon_trans_dom

SCN10A SCN7A ITPR3

2.95e-03114473IPR005821
DomainIon_trans

SCN10A SCN7A ITPR3

2.95e-03114473PF00520
DomainAAA+_ATPase

DNAH2 ASCC3 DNAH8

5.68e-03144473IPR003593
DomainAAA

DNAH2 ASCC3 DNAH8

5.68e-03144473SM00382
DomainGPCR_Rhodpsn_7TM

OXTR GALR2 OR10X1 OR52B6 OR5D13 OR5B17

6.40e-03670476IPR017452
Domain7tm_1

OXTR GALR2 OR10X1 OR52B6 OR5D13 OR5B17

6.73e-03677476PF00001
DomainG_PROTEIN_RECEP_F1_1

OXTR GALR2 OR10X1 OR52B6 OR5D13 OR5B17

7.11e-03685476PS00237
DomainG_PROTEIN_RECEP_F1_2

OXTR GALR2 OR10X1 OR52B6 OR5D13 OR5B17

7.41e-03691476PS50262
DomainGPCR_Rhodpsn

OXTR GALR2 OR10X1 OR52B6 OR5D13 OR5B17

7.46e-03692476IPR000276
DomainChannel_four-helix_dom

SCN10A SCN7A

9.06e-0357472IPR027359
Domain-

SCN10A SCN7A

9.06e-03574721.20.120.350
PathwayREACTOME_SENSORY_PERCEPTION

TAS2R20 BCO2 CALHM3 OR10X1 OR52B6 OR5D13 OR5B17 ITPR3

1.05e-04636348M41834
PathwayREACTOME_SENSORY_PERCEPTION_OF_TASTE

TAS2R20 CALHM3 ITPR3

1.93e-0447343M42524
Pubmed

CD4+ regulatory T cells lacking Helios and Eos.

IKZF2 IKZF4

1.87e-06248237413709
Pubmed

Evolution and diversity of mammalian sodium channel genes.

SCN10A SCN7A

1.12e-05448210198179
Pubmed

A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells.

IKZF2 IKZF4

1.12e-05448222961053
Pubmed

Chromatin remodeling: recruitment of histone demethylase RBP2 by Mad1 for transcriptional repression of a Myc target gene, telomerase reverse transcriptase.

TERT KDM5A

1.12e-05448219762557
Pubmed

Identification of apoptosis-related PLZF target genes.

ZBTB16 TERT

1.86e-05548217537403
Pubmed

Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities.

IKZF2 IKZF4

1.86e-05548210978333
Pubmed

Personal receptor repertoires: olfaction as a model.

OR12D1 OR10X1 OR5D13

2.01e-053848322908908
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH2 DNAH8

3.90e-0574829256245
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH2 DNAH8

3.90e-05748231178125
Pubmed

Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos.

IKZF2 IKZF4

6.67e-05948222638570
Pubmed

Genetic Identification of Vagal Sensory Neurons That Control Feeding.

SCN10A OXTR

8.33e-051048231730854
Pubmed

Binding of pRB to the PHD protein RBP2 promotes cellular differentiation.

ZBTB16 KDM5A

1.02e-041148215949438
Pubmed

Ikaros confers early temporal competence to mouse retinal progenitor cells.

IKZF2 IKZF4

1.44e-041348218940586
Pubmed

A molecular dissection of the repression circuitry of Ikaros.

IKZF2 IKZF4

1.68e-041448212015313
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH2 DNAH8

1.68e-04144829373155
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

MYO1B MSH2 ASCC3 ITPR3

1.76e-0420248433005030
Pubmed

Loss of G9a does not phenocopy the requirement for Prdm12 in the development of the nociceptive neuron lineage.

SCN10A PRDM12

1.94e-041548238167468
Pubmed

Ikaros promotes early-born neuronal fates in the cerebral cortex.

IKZF2 IKZF4

3.14e-041948223382203
Pubmed

Ontogeny and Trophic Factor Sensitivity of Gastrointestinal Projecting Vagal Sensory Cell Types.

SCN10A OXTR

3.14e-041948236973009
Pubmed

Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation.

SCN10A PRDM12

3.49e-042048233789102
Pubmed

Catalog of mRNA expression patterns for DNA methylating and demethylating genes in developing mouse lower urinary tract.

MSH2 APOBEC3D

5.05e-042448223920106
Pubmed

The functional interactome landscape of the human histone deacetylase family.

ZNF521 IKZF2 KDM5A ZNF827

6.81e-0428948423752268
Pubmed

Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation.

ZNF521 PRDM12

8.45e-043148236476860
Pubmed

Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA.

SCN10A PRDM12

9.58e-043348230917309
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

SCN10A SREBF2 MYO1B ITPR3

1.02e-0332248426514267
Pubmed

A probabilistic classifier for olfactory receptor pseudogenes.

OR10X1 OR5D13

1.08e-033548216939646
Pubmed

Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia.

SCN10A PRDM12

1.08e-033548238025786
Pubmed

RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation.

MRGBP KDM5A

1.14e-033648217573780
InteractionSIN3B interactions

IKZF2 ZBTB16 MRGBP KDM5A IKZF4

1.17e-05147415int:SIN3B
Cytoband11q23.1

ZBTB16 BCO2

6.96e-043748211q23.1
CytobandEnsembl 112 genes in cytogenetic band chr22q13

SREBF2 APOBEC3D EFCAB6

5.01e-03330483chr22q13
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF521 PRDM12 ZNF630 ZNF776 IKZF2 ZBTB16 ZNF699 ZNF827 IKZF4

1.35e-0571838928
GeneFamilyDyneins, axonemal

DNAH2 DNAH8

5.73e-0417382536
CoexpressionDESCARTES_FETAL_STOMACH_CILIATED_EPITHELIAL_CELLS

DNAH2 CFAP47 OXTR EFCAB6 C10orf67 SPATA18

1.63e-05317456M40298
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH2 CFAP47 EFCAB6 C10orf67 SPATA18

1.48e-061854755e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH2 CFAP47 OXTR BCO2 SPATA18

1.83e-06193475ea345d34440b25f65358a53dc72831998d1c3620
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IKZF2 TAS2R20 IKZF4 SCN7A

9.53e-06126474feedea978d76de326c14da5149e57d0d767271b9
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IKZF2 TAS2R20 IKZF4 SCN7A

9.53e-061264746311cc64320db7e24a09065ebdf054f5f551b182
ToppCellE12.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP47 ANKRD42 EFCAB6 SPATA18

1.57e-05143474cc396b81a5e47d78c2d1cb49d682391376b63476
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CFAP47 EFCAB6 C10orf67 SPATA18

2.05e-05153474fc0d2d50aa3b6b2772bbf3626c9df5c5e8d7d11e
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CFAP47 EFCAB6 C10orf67 SPATA18

2.05e-051534742482247d9c39c7b99bb45fb9153442f64fd6012f
ToppCellCiliated_cells-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

DNAH2 CFAP47 BCO2 SPATA18

2.82e-051664744b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 EFCAB6 BCO2 WDR17

3.02e-05169474fba841664939c771881ba97f14ef1df6635c04ff
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IKZF2 GALR2 IKZF4 SCN7A

3.24e-05172474b440184f2d98d2f2d59566795f44fb79c0647ca4
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1B ZBTB16 ZNF827 DNAH8

3.95e-05181474709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

DNAH2 CFAP47 EFCAB6 SPATA18

4.03e-05182474fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH2 CFAP47 C10orf67 SPATA18

4.30e-051854743e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

DNAH2 CFAP47 EFCAB6 SPATA18

4.30e-0518547418a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH2 CFAP47 EFCAB6 SPATA18

4.39e-05186474f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH2 CFAP47 C10orf67 SPATA18

4.39e-0518647485787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH2 CFAP47 C10orf67 SPATA18

4.48e-051874749e10ed56090d82589bc457788282f664b70ace4b
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

DNAH2 CFAP47 EFCAB6 SPATA18

4.58e-0518847434b11f72ca73153d02edcd09b38983ad1a504659
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

DNAH2 CFAP47 EFCAB6 SPATA18

4.58e-0518847461a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH2 CFAP47 EFCAB6 SPATA18

4.67e-0518947468a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

DNAH2 CFAP47 EFCAB6 SPATA18

4.67e-05189474b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

DNAH2 CFAP47 EFCAB6 SPATA18

4.67e-0518947427329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH2 CFAP47 EFCAB6 SPATA18

4.67e-051894743e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH2 CFAP47 EFCAB6 SPATA18

4.87e-05191474e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH2 CFAP47 EFCAB6 SPATA18

4.87e-051914749d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OXTR LARS2 IKZF4 SCN7A

4.87e-051914742f733d510a4862565a817f59829d8387d7ea26d9
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OXTR LARS2 IKZF4 SCN7A

4.87e-051914748691eba35793e4e90f93d50c2145847ee51289f7
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH2 CFAP47 EFCAB6 SPATA18

4.87e-051914741c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH2 CFAP47 EFCAB6 SPATA18

5.07e-051934740e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH2 CFAP47 EFCAB6 SPATA18

5.07e-05193474ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH2 CFAP47 EFCAB6 SPATA18

5.17e-051944741ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF699 LARS2 GK5 ITPR3

5.38e-05196474c57a95f8b4d8d6334f269d3c16246684f4222a3e
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Pnoc_(Fast-spiking_interneuron,_Pvalb+/Pnoc+)--|Striatum / BrainAtlas - Mouse McCarroll V32

PRDM12 ZBTB16 EFCAB6

2.13e-0411047341306a2d4a5a39569437eb123e47f98ef8afab24
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Pnoc_(Fast-spiking_interneuron,_Pvalb+/Pnoc+)|Striatum / BrainAtlas - Mouse McCarroll V32

PRDM12 ZBTB16 EFCAB6

2.13e-041104731fe08060248b25329f73b80d74435c108bee1359
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Pnoc_(Fast-spiking_interneuron,_Pvalb+/Pnoc+)-|Striatum / BrainAtlas - Mouse McCarroll V32

PRDM12 ZBTB16 EFCAB6

2.13e-041104735496c92932195386025254b9129d69b12c8e3340
ToppCellThalamus-Macroglia-CSF_related-EPENDYMAL|Thalamus / BrainAtlas - Mouse McCarroll V32

EFCAB6 GALR2 C10orf67

2.89e-041224737ab0b63244116e74c5783c3293cf08224d094d0a
ToppCellThalamus-Macroglia-CSF_related|Thalamus / BrainAtlas - Mouse McCarroll V32

EFCAB6 GALR2 C10orf67

2.89e-04122473eb944243424460bf5c66aced3ed7b7a1b6486ac7
ToppCellThalamus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)-|Thalamus / BrainAtlas - Mouse McCarroll V32

EFCAB6 GALR2 C10orf67

2.89e-04122473aca079f2f033cc1ac13c4ee02d490b6a514cbd5c
ToppCellThalamus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)--|Thalamus / BrainAtlas - Mouse McCarroll V32

EFCAB6 GALR2 C10orf67

2.89e-04122473ac38130010f76648757eac700a8039f3960ddde3
ToppCellThalamus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)|Thalamus / BrainAtlas - Mouse McCarroll V32

EFCAB6 GALR2 C10orf67

2.89e-041224739b0d6b0a394560ff5aadcd3b21519c2393e6def8
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

EFCAB6 C10orf67 SPATA18

3.97e-0413647367d736096d6b6ddb4722809557f5e987063b8d23
ToppCellSubstantia_nigra-Macroglia-CSF_related|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

EFCAB6 C10orf67 SPATA18

3.97e-0413647347663c5d81c766a333207a44fc5b58b07309ee76
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

EFCAB6 C10orf67 SPATA18

3.97e-041364736d2e5b871f4cf8d64e6fe0be666fb3490797c635
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

EFCAB6 C10orf67 SPATA18

3.97e-04136473fd4269d194c7c11c6ab4383393a01efab05cbace
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

EFCAB6 C10orf67 SPATA18

3.97e-041364733f6cec8d52c84191f7f6e2dd4dc47524dfd5b21b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-OPC_related-Oligodendrocyte/OPC|GW26 / Sample Type, Dataset, Time_group, and Cell type.

ZNF630 OXTR SPATA18

4.06e-041374738ce463d1d74ac0ce80b812217d6bd76a788f14d2
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-OPC_related|GW26 / Sample Type, Dataset, Time_group, and Cell type.

ZNF630 OXTR SPATA18

4.06e-04137473264d5e06c37d1a9ef7748091b67d2a5aa803096e
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN10A LARS2 C10orf67

4.79e-0414547396712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Thalamus / BrainAtlas - Mouse McCarroll V32

PRDM12 FRMPD3 OXTR

5.09e-04148473afebb64365c94b9476494bffe7c364677f19c8cf
ToppCellThalamus-Neuronal-Inhibitory|Thalamus / BrainAtlas - Mouse McCarroll V32

PRDM12 FRMPD3 OXTR

5.09e-041484735f82e5ecacfd223020b8ee975c17d68c1fe6db38
ToppCellHealthy_donor-RBC|World / disease group, cell group and cell class (v2)

SPDYE1 PRDM12 MYO1B

5.29e-041504731e1a497ec4b048f7e9cc12dd5dd9aba7fedca9e1
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D2|343B / Donor, Lineage, Cell class and subclass (all cells)

APOBEC3D ZNF699 BCO2

5.60e-041534730b3b199678d4a70b0590393568c69454bece5c14
ToppCell10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-MEMP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ZNF521 PRDM12 ZBTB16

5.60e-0415347314753baa9980f75206fefc3c8b43685fd4178a43
ToppCellHealthy_donor-RBC|Healthy_donor / disease group, cell group and cell class (v2)

SPDYE1 PRDM12 MYO1B

5.71e-04154473e080d5104fe6f3f6ef617bbcdccf1332ab7231e1
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LAMB2 ZNF699 BCO2

6.15e-0415847374aa4f75307575ac3b2b1aa9f727753692f88742
ToppCellControl-B_naive-12|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MYO1B IKZF2 LARS2

6.15e-0415847341318f864770370ce77ed3fa4a84f76c0c22c482
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Tregs|Lung / Manually curated celltypes from each tissue

IKZF2 DNAH8 IKZF4

6.15e-04158473f433bc189f000efa34e8e09ab32b3fa22bcf64c4
ToppCellsevere_COVID-19-pDC|World / disease group, cell group and cell class (v2)

ZNF521 POMK GALR2

6.27e-04159473e1c48c4ceda116826819ff9adeed7bad6a58844d
ToppCellsevere_COVID-19-pDC|severe_COVID-19 / disease group, cell group and cell class (v2)

ZNF521 POMK GALR2

6.27e-04159473ea5088d27e42b8850455764d53b757ea8d8f14bc
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_SOX11|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CFAP47 DNAH8 SCN7A

6.38e-041604734cc34f40b56da39fbd26592fbdb4c07e7318d306
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

LAMB2 ZNF699 BCO2

6.50e-0416147358381131e651744b5141b202f9d6063f55432db5
ToppCell10x5'-Lung-Lymphocytic_T_CD4/8-lo|Lung / Manually curated celltypes from each tissue

SPDYE1 IKZF2 ITPR3

6.50e-04161473a1f10e04836848b1deaf295fae033f54d1572fcd
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4|Lung / Manually curated celltypes from each tissue

DNAH2 EFCAB6 TERT

6.61e-0416247391cc14aec8d580cf97a1929bc1acb00fcbcdb57a
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCN10A LARS2 C10orf67

6.61e-04162473bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellTCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma-Usual_Type-6|TCGA-Adrenal / Sample_Type by Project: Shred V9

APOBEC3D BCO2 IKZF4

6.61e-041624730e8fb83acb8ea9905cc3ca985feb8a00931549ff
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC28A2 IKZF2 IKZF4

6.73e-041634734af92b211d12c5b88b65bb746242cd702b545bd0
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC28A2 IKZF2 IKZF4

6.73e-04163473d24774e0aa612322c22fdb3b314aef275fa01d68
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal-GABAergic_neurons|GW16 / Sample Type, Dataset, Time_group, and Cell type.

ZBTB16 GALR2 ITPR3

6.85e-041644734d7b2d0980fb4f47721fa2891151e2bd892ccb91
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF521 FRMPD3 OXTR

6.98e-04165473347b59aa625a8a960828b8620824d8ac48990e07
ToppCellPND03-Endothelial-Endothelial_lymphatic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF521 FRMPD3 OXTR

6.98e-041654731890f9c33b0c5b381d57f97042da2610a093a6de
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-Tregs|bone_marrow / Manually curated celltypes from each tissue

IKZF2 DNAH8 IKZF4

6.98e-041654731ae1ad4e1fe19b6eefff0f9a03d58a384f169759
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF521 FRMPD3 OXTR

6.98e-04165473507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF521 FRMPD3 OXTR

6.98e-0416547339a25be081a5d59c7cf107a997d352793d5025fb
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TERT GALR2 SCN7A

7.10e-04166473aa2df07eff323ded751ced8938af08223d7f2029
ToppCellmild-Lymphocytic-CD4_T_cells_3|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

IKZF2 DNAH8 IKZF4

7.10e-04166473f8f8423423d72f0ea0266b59126abb27beb23094
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TERT GALR2 SCN7A

7.10e-04166473695298a94d62b8adab083900003ec636fbaae5d9
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 IKZF2 BCO2

7.22e-04167473eed22d1a17aab84dacb1a488528bae9389644cb9
ToppCell15-Distal-Epithelial-Multiciliated_cell|Distal / Age, Tissue, Lineage and Cell class

DNAH2 C10orf67 SPATA18

7.48e-04169473425d89ab69e9f9eb3df84056676423e390cc6ab1
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 IKZF2 BCO2

7.48e-04169473b08567ecfa3f8d83e7990330fc1b27f0bb7e75a1
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6|TCGA-Liver / Sample_Type by Project: Shred V9

ZNF521 WDR17 SCN7A

7.48e-04169473e992530776cab922d0360b275fb9cb8bd0017b06
ToppCellCV-Mild-7|CV / Virus stimulation, Condition and Cluster

MYO1B ZNF630 ZNF776

7.61e-0417047325ebde7d2f8ae1afdfaf5876284ff20bb179eb10
ToppCellfacs|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SREBF2 MRGBP LARS2

7.74e-04171473c9990bc041a632b2f7bbebbfe737772c423d7027
ToppCell10x5'-GI_small-bowel-Lymphocytic_NK-NK_CD16|GI_small-bowel / Manually curated celltypes from each tissue

FRMPD3 TAS2R20 GK5

7.74e-041714731ee505b91f15191d294a5d491ecdf154c08b8622
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

CFAP47 BCO2 C10orf67

7.74e-0417147374be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH2 CFAP47 SPATA18

7.74e-041714734f2a83d8091f1fd29542d2e5add57fd482e921b5
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-eo/baso/mast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ZNF521 PRDM12 ZBTB16

7.87e-041724737fb43b3938b9a3b6935ec22d9d853e7d47b82b3c
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-NK_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ZBTB16 ZNF827 SCN7A

7.87e-04172473a126dacd94939851de1403d30f0b63eaad48bfa1
ToppCellCV-Mild-7|Mild / Virus stimulation, Condition and Cluster

MYO1B ZNF630 ZNF776

8.00e-04173473c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SREBF2 CFAP47 IKZF2

8.00e-041734730f9c1d3298e59e6d22bb3306f0f445f490be8bbd
ToppCellControl-Lymphocyte-T_NK-gdT|Control / Disease, Lineage and Cell Type

IKZF2 FRMPD3 OXTR

8.13e-04174473202d222a53f967cce172e5f3f1b40920ea13ec6c
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP47 ANKRD42 C10orf67

8.13e-04174473f1510b0f7771936adf29ae3572feab55db31832b
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP47 ANKRD42 C10orf67

8.13e-041744735d5d2fc60afff47f997751e8e9ca1367a22d19ec
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANKRD42 C10orf67 SPATA18

8.13e-04174473179a52d77899a929396b98d4ab2c270dd2ec708e
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANKRD42 C10orf67 SPATA18

8.13e-041744739165a1094d345328e58962f4b2a20334c3e93ead
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 C10orf67 SPATA18

8.41e-04176473d6d7e4e937d49a5c0d16322c8dd3bf9e97eb8732
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TERT DNAH8 SCN7A

8.41e-0417647388ca2f83d8301633232735f39b0683efe49d0b86
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TERT DNAH8 SCN7A

8.41e-041764737292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 C10orf67 SPATA18

8.41e-04176473c03d80df2550c0d2b0452326480d6bf21d20fdd2
ToppCell3'_v3-lymph-node_spleen-Mast-Mast_cell_lympho|lymph-node_spleen / Manually curated celltypes from each tissue

IKZF2 GK5 DNAH8

8.55e-0417747353040dbeb18574a48e352e4bce252c7c3018762c
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP47 C10orf67 SPATA18

8.69e-04178473de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
DiseaseCongenital Pain Insensitivity

SCN10A PRDM12

4.75e-057452C0002768
Diseasesmoking status measurement

SREBF2 ZNF521 MYO1B IKZF2 ZBTB16 ASCC3 GK5 DNAH8 IKZF4

5.37e-051160459EFO_0006527
Diseaseprostate cancer (is_marker_for)

SREBF2 MSH2 TERT KDM5A

9.46e-05156454DOID:10283 (is_marker_for)
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN10A SCN7A

1.02e-0410452DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN10A SCN7A

1.02e-0410452DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN10A SCN7A

1.49e-0412452DOID:0060170 (implicated_via_orthology)
DiseaseMajor Depressive Disorder

ZBTB16 OXTR TERT GALR2

5.13e-04243454C1269683
DiseaseUnipolar Depression

ZBTB16 OXTR TERT GALR2

6.51e-04259454C0041696
Diseasemyeloproliferative disorder

ZNF521 TERT

6.67e-0425452EFO_0004251
Diseasecentral nervous system cancer, glioma

ZBTB16 TERT

8.99e-0429452EFO_0000326, EFO_0005543
Diseasecentral nervous system cancer

ZBTB16 TERT

1.03e-0331452EFO_0000326
DiseaseCognition Disorders

LAMB2 OXTR

1.54e-0338452C0009241
Diseasecervix uteri carcinoma in situ (is_marker_for)

MSH2 TERT

1.88e-0342452DOID:8991 (is_marker_for)
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

MSH2 TERT

2.16e-0345452DOID:3748 (is_implicated_in)
Diseaselung non-small cell carcinoma (is_marker_for)

MSH2 IKZF2 KDM5A

2.20e-03169453DOID:3908 (is_marker_for)
Diseaselung adenocarcinoma (is_implicated_in)

MSH2 TERT

2.56e-0349452DOID:3910 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
VVFFRVKEILHCHSM

ARHGEF10L

361

Q9HCE6
LCFTMEVTKHHSAVF

APOBEC3D

231

Q96AK3
RDFAHRCVLHFFASM

CALHM3

236

Q86XJ0
MFFRVFLHFIRSHSA

BCO2

1

Q9BYV7
HLHCFKFLVSRMSSA

ANKRD42

176

Q8N9B4
FDLRASFCHLMLHVH

ITPR3

771

Q14573
KHFFCHMLAVIRLSC

OR10X1

191

Q8NGY0
EAFHVAKMAFRHFKI

SPATA18

341

Q8TC71
MFFIHFLFIHSAVLL

OR52B6

121

Q8NGF0
SCVEHLHKLFVFGLM

DNAH8

2341

Q96JB1
AEFHFTHLIMTFKTF

LAMB2

141

P55268
HMRIHTLDKPFVCRF

PRDM12

261

Q9H4Q4
HSRLFFFMKHLSIAD

OXTR

71

P30559
FKCEHCRVLFLDHVM

IKZF2

471

Q9UKS7
RRHCVFSHEELIFKM

KDM5A

606

P29375
HLFFKTHSFSMLRKA

OR12D1

216

P0DN82
LLCKAVHFLIFLTMH

GALR2

96

O43603
KIMHVFCPFLTNAHF

EFCAB6

531

Q5THR3
RTHYHGMKCLFRISF

FRMPD3

251

Q5JV73
MKIFHSSCRVLHFFT

GK5

136

Q6ZS86
RSFFFMSEKALTNHH

FAM172BP

91

A6NC97
RTLFERHKLLFSFHM

DNAH2

3676

Q9P225
REFFCSMHTVHLGVK

CFAP47

2066

Q6ZTR5
ATKIGAFCMFATHFH

MSH2

771

P43246
KCEHCRILFLDHVMF

IKZF4

531

Q9H2S9
TFRLSFCMSNVIHHF

OR5B17

161

Q8NGF7
KLHTIMCFFLSHLSL

OR5D13

56

Q8NGL4
SLFFLVCHLVMKHTY

TAS2R20

136

P59543
ARFFSHFCHDQKMVK

LARS2

571

Q15031
VNRHFHMICIRDKFS

MRGBP

51

Q9NV56
FLHICTHAFFKAMLF

MT-ND5

326

P03915
HKDAHSFLSDICMFR

WDR17

166

Q8IZU2
MVRFHLFDIHKACKS

POMK

301

Q9H5K3
CMFILILFACSKHHS

SLC28A2

181

O43868
FLFMTFHLKDSVGHK

ASCC3

96

Q8N3C0
FHVLKNEMFTRHTLF

C10orf67

451

Q8IYJ2
VLACTSKMFEILFHR

ZBTB16

51

Q05516
HMHDFFHSFLIVFRI

SCN10A

831

Q9Y5Y9
KHLLDMHTFVFFRCT

ZNF521

711

Q96K83
VLFQKRRFHFFCSMS

SPDYE1

291

Q8NFV5
LVKAIFHACRAMHAS

SREBF2

916

Q12772
PFSVVVFHCRHMFHK

VPS41

806

P49754
RKAFCEMSHLFIHQI

ZNF630

381

Q2M218
HLITRMFECDVCHKF

ZNF827

1041

Q17R98
MHDFFHSFLNVFRIL

SCN7A

671

Q01118
SCSSFFRAHMKIHIG

ZNF699

261

Q32M78
FDVFLRFMCHHAVRI

TERT

806

O14746
FLVFAHHLSMLQACT

ZRANB3

341

Q5FWF4
FVKNCKFHMSHEPFI

ZNF776

151

Q68DI1
HQHFESRMSKCSRFL

MYO1B

486

O43795