Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessnegative regulation of neuron migration

ADGRG1 STAT3 TNN CX3CL1

2.54e-06131634GO:2001223
GeneOntologyBiologicalProcessvisual learning

RAG1 DCDC2 PDE1B GRIN1 RGS14 NPTN TANC1

2.79e-06781637GO:0008542
GeneOntologyBiologicalProcessvisual behavior

RAG1 DCDC2 PDE1B GRIN1 RGS14 NPTN TANC1

5.38e-06861637GO:0007632
GeneOntologyBiologicalProcessmembrane depolarization during action potential

CACNB2 ANK2 HCN4 SCN1A SCN9A

8.96e-06361635GO:0086010
GeneOntologyBiologicalProcessresponse to light stimulus

RAG1 DCDC2 PDE1B GRIN1 IRX6 INO80 GPR179 CIRBP MSH6 RGS14 NPTN GUCY2D TANC1

1.13e-0538216313GO:0009416
GeneOntologyBiologicalProcessregulation of odontogenesis

APC RUNX2 DICER1 IFT88

3.53e-05241634GO:0042481
GeneOntologyBiologicalProcessresponse to radiation

RAG1 DCDC2 PDE1B GRIN1 IRX6 INO80 GPR179 CIRBP MSH6 RGS14 NPTN GUCY2D TANC1 TMEM109

4.81e-0550316314GO:0009314
GeneOntologyBiologicalProcesslearning

RAG1 DCDC2 PDE1B GRIN1 RGS14 NPTN KCNQ2 TANC1 STRA6

4.93e-052121639GO:0007612
GeneOntologyBiologicalProcessmembrane depolarization

CACNB2 ANK2 HCN4 GPD1L SCN1A SCN9A KCNQ2

5.02e-051211637GO:0051899
GeneOntologyBiologicalProcesszygote asymmetric cell division

DICER1 RGS14

6.21e-0521632GO:0010070
GeneOntologyBiologicalProcesscardiac muscle cell action potential

CACNB2 ANK2 HCN4 GPD1L SCN1A SCN9A

6.61e-05871636GO:0086001
GeneOntologyBiologicalProcessspindle organization

RCC1 FSD1 CEP192 INO80 DICER1 RGS14 CEP72 STARD9 PSRC1

7.54e-052241639GO:0007051
GeneOntologyBiologicalProcessassociative learning

RAG1 DCDC2 PDE1B GRIN1 RGS14 NPTN TANC1

7.92e-051301637GO:0008306
GeneOntologyBiologicalProcessbehavior

RAG1 DCDC2 PDE1B DSCAM CHD8 GRIN1 RUNX1 STAT3 RGS14 NPTN CELSR1 IFT88 SCN1A SCN9A KCNQ2 KCNAB1 TANC1 STRA6 RASD2

8.23e-0589116319GO:0007610
GeneOntologyBiologicalProcesscardiac muscle cell contraction

CACNB2 ANK2 HCN4 GPD1L SCN1A SCN9A

9.60e-05931636GO:0086003
GeneOntologyBiologicalProcessactin filament-based process

FLNC CACNB2 ANK2 HCN4 EPB41L4B IQSEC2 MINK1 GPD1L TYROBP CELSR1 SCN1A SCN9A PDXP PIP5K1A CGNL1 PLEKHH2 CX3CL1 FGD6 SMTNL2

1.12e-0491216319GO:0030029
GeneOntologyBiologicalProcesssensory perception of mechanical stimulus

DCDC2 TSPEAR GRXCR1 ITGA2 OTOF SCN1A SCN9A KCNQ2 PPIP5K2

1.20e-042381639GO:0050954
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

CACNB2 ANK2 GPD1L SCN1A SCN9A

1.30e-04621635GO:0086002
GeneOntologyBiologicalProcessregulation of neuron migration

SCRT1 ADGRG1 STAT3 TNN CX3CL1

1.30e-04621635GO:2001222
GeneOntologyBiologicalProcesspositive regulation of mitochondrial RNA catabolic process

PNPT1 SUPV3L1

1.85e-0431632GO:0000962
GeneOntologyBiologicalProcessmitochondrial mRNA catabolic process

PNPT1 SUPV3L1

1.85e-0431632GO:0000958
GeneOntologyBiologicalProcessaction potential

CACNB2 DCDC2 ANK2 HCN4 GPD1L SCN1A SCN9A KCNQ2

2.02e-042011638GO:0001508
GeneOntologyBiologicalProcessregulation of odontogenesis of dentin-containing tooth

RUNX2 DICER1 IFT88

2.06e-04151633GO:0042487
GeneOntologyBiologicalProcessnegative regulation of mRNA metabolic process

DICER1 HNRNPCL3 CIRBP ACIN1 DHX34 HNRNPCL2

3.07e-041151636GO:1903312
GeneOntologyCellularComponentmitochondrial degradosome

PNPT1 SUPV3L1

6.27e-0521662GO:0045025
GeneOntologyCellularComponent9+2 non-motile cilium

DCDC2 GRXCR1 IFT88

1.68e-04141663GO:0097732
GeneOntologyCellularComponentkinocilium

DCDC2 GRXCR1 IFT88

1.68e-04141663GO:0060091
GeneOntologyCellularComponentcore-binding factor complex

RUNX1 RUNX3

1.87e-0431662GO:0016513
HumanPhenoAortopulmonary collateral arteries

FLT4 PKD1L1 SCN1A KCNQ2

1.76e-0515574HP:0031834
HumanPhenoFacial tics

PNPT1 SCN1A SCN9A KCNQ2

1.76e-0515574HP:0011468
MousePhenoneonatal lethality

FLNC FLT4 AMER1 ANK2 DSCAM MYT1 USP24 LAMA4 GBX2 GRIN1 RUNX2 RUNX1 RUNX3 SH2B1 KIF7 EHBP1L1 TIE1 GLCE SCN1A DUSP16 SCN9A KCNQ2

6.06e-0679913322MP:0002058
MousePhenoperinatal lethality

FLNC FLT4 AMER1 ANK2 DSCAM MYT1 USP24 APC LAMA4 GBX2 GRIN1 RUNX2 RUNX1 RUNX3 DICER1 SH2B1 STAT3 KIF7 CELSR1 EHBP1L1 TIE1 GLCE SCN1A DUSP16 SCN9A KCNQ2

1.96e-05113013326MP:0002081
MousePhenoperinatal lethality, complete penetrance

FLNC FLT4 AMER1 DSCAM MYT1 USP24 APC GBX2 GRIN1 RUNX2 STAT3 KIF7 CELSR1 EHBP1L1 TIE1 GLCE DUSP16 SCN9A KCNQ2

4.31e-0571213319MP:0011089
MousePhenoneonatal lethality, complete penetrance

FLNC FLT4 AMER1 DSCAM MYT1 USP24 GBX2 GRIN1 RUNX2 KIF7 EHBP1L1 TIE1 GLCE DUSP16 SCN9A KCNQ2

4.72e-0553413316MP:0011087
MousePhenolethality during fetal growth through weaning, complete penetrance

FLNC FLT4 AMER1 ANK2 DSCAM MYT1 PKD1L1 USP24 APC GBX2 GRIN1 RUNX2 RUNX1 RUNX3 DICER1 STAT3 KIF7 RCOR1 CELSR1 EHBP1L1 TIE1 GLCE SCN1A DUSP16 SCN9A KCNQ2 STRA6

5.24e-05126913327MP:0011111
MousePhenoabnormal spatial learning

DCDC2 ANK2 PDE1B IQSEC2 GRIN1 RGS14 SCN1A PDXP KCNQ2 KCNAB1 HDC

6.53e-0527613311MP:0001463
MousePhenodecreased methionine level

PDXP MTRR

8.98e-0521332MP:0030642
DomainRunt

RUNX2 RUNX1 RUNX3

6.65e-0731643PF00853
DomainRUNT

RUNX2 RUNX1 RUNX3

6.65e-0731643PS51062
DomainTF_Runt-rel_RUNX

RUNX2 RUNX1 RUNX3

6.65e-0731643IPR016554
DomainRunxI

RUNX2 RUNX1 RUNX3

6.65e-0731643PF08504
DomainRunt_dom

RUNX2 RUNX1 RUNX3

6.65e-0731643IPR013524
DomainRunxI_C_dom

RUNX2 RUNX1 RUNX3

6.65e-0731643IPR013711
DomainRunx_central_dom

RUNX2 RUNX1 RUNX3

6.65e-0731643IPR027384
Domain-

RUNX2 RUNX1 RUNX3

6.65e-07316434.10.770.10
DomainAML1_Runt

RUNX2 RUNX1 RUNX3

6.65e-0731643IPR000040
DomainHelicase_C

DHX40 CHD8 INO80 DICER1 SUPV3L1 POLQ DHX34 DDX4

4.65e-061071648PF00271
DomainHELICc

DHX40 CHD8 INO80 DICER1 SUPV3L1 POLQ DHX34 DDX4

4.65e-061071648SM00490
DomainHelicase_C

DHX40 CHD8 INO80 DICER1 SUPV3L1 POLQ DHX34 DDX4

4.98e-061081648IPR001650
DomainHELICASE_CTER

DHX40 CHD8 INO80 DICER1 SUPV3L1 POLQ DHX34 DDX4

5.33e-061091648PS51194
DomainHELICASE_ATP_BIND_1

DHX40 CHD8 INO80 DICER1 SUPV3L1 POLQ DHX34 DDX4

5.33e-061091648PS51192
Domainp53/RUNT-type_TF_DNA-bd

RUNX2 RUNX1 RUNX3

1.30e-0561643IPR012346
Domain-

RUNX2 RUNX1 RUNX3

1.30e-05616432.60.40.720
DomainDEXDc

DHX40 CHD8 INO80 DICER1 POLQ DHX34 DDX4

4.98e-051091647SM00487
DomainHelicase_ATP-bd

DHX40 CHD8 INO80 DICER1 POLQ DHX34 DDX4

5.28e-051101647IPR014001
DomainLUC7

LUC7L LUC7L2

2.29e-0431642PF03194
DomainLuc7-rel

LUC7L LUC7L2

2.29e-0431642IPR004882
DomainDEAD/DEAH_box_helicase_dom

DHX40 DICER1 POLQ DHX34 DDX4

4.56e-04731645IPR011545
DomainDEAD

DHX40 DICER1 POLQ DHX34 DDX4

4.56e-04731645PF00270
DomainP-loop_NTPase

EFL1 CACNB2 DHX40 SMC6 CHST6 CHD8 INO80 DICER1 KIF7 MSH6 STARD9 SUPV3L1 RAB43 ABCG2 POLQ DHX34 DDX4 RASD2

4.82e-0484816418IPR027417
DomainRRM

RBM12B ZRSR2 CIRBP RBM15B RBM6 ACIN1 HNRNPCL4 HNRNPCL2

6.77e-042171648SM00360
Domain-

EFL1 CACNB2 DHX40 SMC6 CHST6 CHD8 INO80 DICER1 MSH6 SUPV3L1 RAB43 ABCG2 POLQ DHX34 DDX4 RASD2

8.98e-04746164163.40.50.300
DomainRRM_dom

RBM12B ZRSR2 CIRBP RBM15B RBM6 ACIN1 HNRNPCL4 HNRNPCL2

9.07e-042271648IPR000504
DomainNa_trans_cytopl

SCN1A SCN9A

1.12e-0361642PF11933
DomainNa_trans_cytopl

SCN1A SCN9A

1.12e-0361642IPR024583
DomainhnRNP_C

HNRNPCL4 HNRNPCL2

1.12e-0361642IPR017347
Domainp53-like_TF_DNA-bd

RUNX2 RUNX1 RUNX3 STAT3

1.20e-03531644IPR008967
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

EPB41L4B DHX40 MINK1 APC CHD8 DICER1 POLR3A HNRNPCL3 GTF3C1 LUC7L2 SUPV3L1 PIP5K1A HNRNPCL4 TANC1 PPIP5K2 PLCH1 DHX34 HR

3.46e-096501691838777146
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

FLNC SLC25A6 RBM12B ZRSR2 APC RCC1 INO80 IWS1 CIRBP CEP170 PNPT1 LUC7L MSH6 EHBP1L1 GTF3C1 LUC7L2 SMU1 RBM15B RBM6 SEC61B ACIN1 PPIP5K2

1.63e-0810821692238697112
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

AMER1 IQSEC2 MINK1 BACH1 APC FAM117B FSD1 CEP192 STAT3 CEP170 LUC7L STARD9 TANC1 CGNL1 PPIP5K2 PLCH1 FGD6 ARAP2 VCPIP1

4.69e-088611691936931259
Pubmed

AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization.

RUNX2 RUNX1 RUNX3

1.13e-07316937835892
Pubmed

Identification and comparative analysis of a second runx3 promoter.

RUNX2 RUNX1 RUNX3

1.13e-073169311483356
Pubmed

Expression of Runx1, -2 and -3 during tooth, palate and craniofacial bone development.

RUNX2 RUNX1 RUNX3

1.13e-073169314516670
Pubmed

Shared and distinct roles mediated through C-terminal subdomains of acute myeloid leukemia/Runt-related transcription factor molecules in murine development.

RUNX2 RUNX1 RUNX3

1.13e-073169315713794
Pubmed

Genetic regulation of the RUNX transcription factor family has antitumor effects.

RUNX2 RUNX1 RUNX3

1.13e-073169328530640
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

FLNC CACNB2 ANK2 EPB41L4B IQSEC2 MINK1 APC GRIN1 ITGA2 GFAP LRCH3 HNRNPCL3 CEP170 GPD1L AGBL4 NPTN SMU1 KCNQ2 PACS2 TANC1 CGNL1 PRKAG2 PLCH1 HNRNPCL2

1.28e-0714311692437142655
Pubmed

Anterior cleft palate due to Cbfb deficiency and its rescue by folic acid.

RUNX2 RUNX1 RUNX3 STAT3

3.72e-0713169431171577
Pubmed

The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells.

RUNX2 RUNX1 RUNX3

4.49e-074169325185713
Pubmed

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

RUNX2 RUNX1 RUNX3

4.49e-074169312464175
Pubmed

Dual color FISH on CBF primary acute myeloid leukemia.

RUNX2 RUNX1 RUNX3

4.49e-074169320306685
Pubmed

Mutagenesis of the Runt domain defines two energetic hot spots for heterodimerization with the core binding factor beta subunit.

RUNX2 RUNX1 RUNX3

4.49e-074169312807883
Pubmed

Evolution of the interaction between Runx2 and VDR, two transcription factors involved in osteoblastogenesis.

RUNX2 RUNX1 RUNX3

4.49e-074169320236534
Pubmed

Central Role of Core Binding Factor β2 in Mucosa-Associated Lymphoid Tissue Organogenesis in Mouse.

RUNX2 RUNX1 RUNX3

4.49e-074169326001080
Pubmed

Isolation of PEBP2 alpha B cDNA representing the mouse homolog of human acute myeloid leukemia gene, AML1.

RUNX2 RUNX1 RUNX3

4.49e-07416938437866
Pubmed

Inflammation-driven colon neoplasmatogenesis in uPA-deficient mice is associated with an increased expression of Runx transcriptional regulators.

RUNX2 RUNX1 RUNX3

4.49e-074169329107070
Pubmed

A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator.

RUNX2 RUNX1 RUNX3

4.49e-074169310228168
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

ANK2 EPB41L4B IQSEC2 GRIN1 SCN1A KCNQ2 KCNAB1 TANC1 UBASH3B

5.72e-07197169936604605
Pubmed

Oncogenic Runx1-Myc axis in p53-deficient thymic lymphoma.

RUNX2 RUNX1 RUNX3

1.12e-065169335114276
Pubmed

Runx3 is required for oncogenic Myc upregulation in p53-deficient osteosarcoma.

RUNX2 RUNX1 RUNX3

1.12e-065169334803166
Pubmed

Transcriptional regulation of osteopontin gene in vivo by PEBP2alphaA/CBFA1 and ETS1 in the skeletal tissues.

RUNX2 RUNX1 RUNX3

1.12e-06516939794229
Pubmed

Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis.

RAG1 APC STAT3

1.12e-065169326880802
Pubmed

Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1.

RUNX2 RUNX1 RUNX3

1.12e-065169317377532
Pubmed

Interplay between SOX7 and RUNX1 regulates hemogenic endothelial fate in the yolk sac.

RUNX2 RUNX1 RUNX3

1.12e-065169327802172
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MINK1 BACH1 USP24 RCC1 SNX33 RUNX1 IWS1 MSH6 RIF1 GTF3C1 BRPF1 RBM15B RBM6 ACIN1 PACS2 VCPIP1

1.34e-067741691615302935
Pubmed

Runx1 and Cbfβ regulate the development of Flt3+ dendritic cell progenitors and restrict myeloproliferative disorder.

RUNX2 RUNX1 RUNX3

2.23e-066169324677539
Pubmed

The essential requirement for Runx1 in the development of the sternum.

RUNX2 RUNX1 RUNX3

2.23e-066169320152828
Pubmed

Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes.

RAG1 RUNX1 RUNX3

2.23e-066169328951542
Pubmed

Transcription factors Runx1 to 3 are expressed in the lacrimal gland epithelium and are involved in regulation of gland morphogenesis and regeneration.

RUNX2 RUNX1 RUNX3

2.23e-066169323532528
Pubmed

RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2.

RUNX2 RUNX1 RUNX3 DDX4

3.02e-0621169431712577
Pubmed

Runx1 and Runx2 cooperate during sternal morphogenesis.

RUNX2 RUNX1 RUNX3

3.89e-067169320181744
Pubmed

The distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration: findings in murine models and in human disease.

RUNX2 RUNX1 RUNX3

3.89e-067169318759297
Pubmed

Associations between genetic variation in RUNX1, RUNX2, RUNX3, MAPK1 and eIF4E and riskof colon and rectal cancer: additional support for a TGF-β-signaling pathway.

RUNX2 RUNX1 RUNX3

3.89e-067169321088106
Pubmed

Bone morphogenic protein (BMP) signaling up-regulates neutral sphingomyelinase 2 to suppress chondrocyte maturation via the Akt protein signaling pathway as a negative feedback mechanism.

RUNX2 RUNX1 RUNX3

3.89e-067169324505141
Pubmed

Physical and functional link of the leukemia-associated factors AML1 and PML.

RUNX2 RUNX1 RUNX3

3.89e-067169315331439
Pubmed

A human MAP kinase interactome.

FLNC MKNK2 APC RAP1GAP2 LAMA4 CHD8 CCDC88B GFAP RIF1 DUSP16 CGNL1 CPLANE1

5.08e-064861691220936779
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNB2 ANK2 PDE1B DSCAM HCN4 IQSEC2 MINK1 WDR81 APC CHD8 GRIN1 KIF7 CEP170 NPTN RCOR1 KCNAB1 UBASH3B

5.14e-069631691728671696
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

TGIF2 SLC25A6 CHD8 RUNX2 RUNX1 RUNX3 POLR3A RIF1 RCOR1 GTF3C1 SMU1 SEC61B ACIN1

6.13e-065831691329844126
Pubmed

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter.

RUNX2 RUNX1 RUNX3

6.20e-068169310531362
Pubmed

Early onset of Runx2 expression caused craniosynostosis, ectopic bone formation, and limb defects.

RUNX2 RUNX1 RUNX3

6.20e-068169321807129
Pubmed

Dominance of SOX9 function over RUNX2 during skeletogenesis.

RUNX2 RUNX1 RUNX3

6.20e-068169317142326
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

BACH1 USP24 APC RCC1 CHD8 IWS1 MSH6 RIF1 GTF3C1 RBM6 ACIN1 PSRC1

7.19e-065031691216964243
Pubmed

Runx1 contributes to neurofibromatosis type 1 neurofibroma formation.

RUNX2 RUNX1 RUNX3

9.27e-069169326073082
Pubmed

The MicroRNA-183-96-182 Cluster Promotes T Helper 17 Cell Pathogenicity by Negatively Regulating Transcription Factor Foxo1 Expression.

RAG1 DICER1 STAT3

9.27e-069169327332731
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

FLNC AMER1 SLC25A6 DHX40 SMC6 APC CIRBP CEP170 PNPT1 MSH6 LUC7L2 SEC61B ACIN1 TANC1 TMEM109

1.07e-058091691532129710
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

ANKRD35 AMER1 EPB41L4B PKD1L1 CCDC88B CEP170 LUC7L OTOF RBM15B CPLANE1

1.19e-053611691026167880
Pubmed

The cDNA cloning of the transcripts of human PEBP2alphaA/CBFA1 mapped to 6p12.3-p21.1, the locus for cleidocranial dysplasia.

RUNX2 RUNX1

2.35e-05216929233771
Pubmed

Long-chain saturated fatty acids in breast milk are associated with the pathogenesis of atopic dermatitis via induction of inflammatory ILC3s.

RAG1 HR

2.35e-052169234162906
Pubmed

Expression patterns and prognostic value of RUNX genes in kidney cancer.

RUNX1 RUNX3

2.35e-052169234294773
Pubmed

Downregulation of RUNX1 by RUNX3 requires the RUNX3 VWRPY sequence and is essential for Epstein-Barr virus-driven B-cell proliferation.

RUNX1 RUNX3

2.35e-052169219403666
Pubmed

Identification of sequence variants influencing immunoglobulin levels.

RUNX2 RUNX3

2.35e-052169228628107
Pubmed

BACH1 promotes lung adenocarcinoma cell metastasis through transcriptional activation of ITGA2.

BACH1 ITGA2

2.35e-052169237311571
Pubmed

Runx3 Regulates CD8+ T Cell Local Expansion and CD43 Glycosylation in Mice by H1N1 Influenza A Virus Infection.

SPN RUNX3

2.35e-052169238673806
Pubmed

ITGA2 as a prognostic factor of glioma promotes GSCs invasion and EMT by activating STAT3 phosphorylation.

ITGA2 STAT3

2.35e-052169238142122
Pubmed

Lymphocytes and the Dap12 adaptor are key regulators of osteoclast activation associated with gonadal failure.

RAG1 TYROBP

2.35e-052169217611620
Pubmed

Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells.

DICER1 ABCG2

2.35e-052169221878538
Pubmed

RUNX super-enhancer control through the Notch pathway by Epstein-Barr virus transcription factors regulates B cell growth.

RUNX1 RUNX3

2.35e-052169226883634
Pubmed

Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis.

RUNX2 RUNX1

2.35e-052169216059634
Pubmed

Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin-Independent Targets by Proteomics.

MINK1 APC

2.35e-052169231160382
Pubmed

Runx2/DICER/miRNA Pathway in Regulating Osteogenesis.

RUNX2 DICER1

2.35e-052169227064596
Pubmed

Runx1 and Runx3 Are Downstream Effectors of Nanog in Promoting Osteogenic Differentiation of the Mouse Mesenchymal Cell Line C3H10T1/2.

RUNX1 RUNX3

2.35e-052169226053522
Pubmed

Case-control association study of rare nonsynonymous variants of SCN1A and KCNQ2 in acute encephalopathy with biphasic seizures and late reduced diffusion.

SCN1A KCNQ2

2.35e-052169232276107
Pubmed

Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia.

RUNX2 RUNX1

2.35e-052169223321257
Pubmed

Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the ApcMin model of colorectal cancer.

APC PACS2

2.35e-052169229312533
Pubmed

Spatial and temporal expression pattern of Runx3 (Aml2) and Runx1 (Aml1) indicates non-redundant functions during mouse embryogenesis.

RUNX1 RUNX3

2.35e-052169211731260
Pubmed

INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis.

APC INO80

2.35e-052169229383140
Pubmed

Expression of AML/Runx and ETO/MTG family members during hematopoietic differentiation of embryonic stem cells.

RUNX2 RUNX1

2.35e-052169217533052
Pubmed

Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer.

RAG1 RUNX2

2.35e-052169225056120
Pubmed

A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice.

RUNX2 RUNX1

2.35e-052169227634876
Pubmed

Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder.

CGNL1 PRKAG2

2.35e-052169221305692
Pubmed

Stat3 activation in murine colitis induced by enterotoxigenic Bacteroides fragilis.

RAG1 STAT3

2.35e-052169224704822
Pubmed

Identification and expression of a novel 3'-exon of mouse Runx1/Pebp2alphaB/Cbfa2/AML1 gene.

RUNX2 RUNX1

2.35e-052169210903914
Pubmed

Localization of the domains in Runx transcription factors required for the repression of CD4 in thymocytes.

RUNX1 RUNX3

2.35e-052169215034051
Pubmed

PSM/SH2B1 splice variants: critical role in src catalytic activation and the resulting STAT3s-mediated mitogenic response.

SH2B1 STAT3

2.35e-052169218247337
Pubmed

Human mitochondrial RNA decay mediated by PNPase-hSuv3 complex takes place in distinct foci.

PNPT1 SUPV3L1

2.35e-052169223221631
Pubmed

AMER1 regulates the distribution of the tumor suppressor APC between microtubules and the plasma membrane.

AMER1 APC

2.35e-052169217925383
Pubmed

Oral interleukin-10 alleviates polyposis via neutralization of pathogenic T-regulatory cells.

RAG1 APC

2.35e-052169225228656
Pubmed

An Essential Role for the Transcription Factor Runx1 in T Cell Maturation.

RAG1 RUNX1

2.35e-052169227020276
Pubmed

Runx1/3-driven adaptive endoplasmic reticulum stress pathways contribute to neurofibromagenesis.

RUNX1 RUNX3

2.35e-052169236759572
Pubmed

Human mitochondrial SUV3 and polynucleotide phosphorylase form a 330-kDa heteropentamer to cooperatively degrade double-stranded RNA with a 3'-to-5' directionality.

PNPT1 SUPV3L1

2.35e-052169219509288
Pubmed

Human mitochondrial RNA turnover caught in flagranti: involvement of hSuv3p helicase in RNA surveillance.

PNPT1 SUPV3L1

2.35e-052169219864255
Pubmed

Relapsing-remitting central nervous system autoimmunity mediated by GFAP-specific CD8 T cells.

RAG1 GFAP

2.35e-052169224591371
Pubmed

Stat3 is a negative regulator of intestinal tumor progression in Apc(Min) mice.

APC STAT3

2.35e-052169219962983
Pubmed

Retroviral insertional mutagenesis identifies RUNX genes involved in chronic myeloid leukemia disease persistence under imatinib treatment.

RUNX1 RUNX3

2.35e-052169217360569
Pubmed

RUNX1 and RUNX2 transcription factors function in opposing roles to regulate breast cancer stem cells.

RUNX2 RUNX1

2.35e-052169232180230
Pubmed

Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles.

RUNX2 RUNX1

2.35e-052169217290219
Pubmed

Runx1 and Runx3 drive progenitor to T-lineage transcriptome conversion in mouse T cell commitment via dynamic genomic site switching.

RUNX1 RUNX3

2.35e-052169233479171
Pubmed

Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells.

RUNX2 RUNX1

2.35e-052169235551452
Pubmed

Expression of Stat3 in germ cells of developing and adult mouse ovaries and testes.

STAT3 DDX4

2.35e-052169215749075
Pubmed

Neuroblastoma cell proliferation is sensitive to changes in levels of RUNX1 and RUNX3 protein.

RUNX1 RUNX3

2.35e-052169221640801
Pubmed

Transcriptional repression of the RUNX3/AML2 gene by the t(8;21) and inv(16) fusion proteins in acute myeloid leukemia.

RUNX1 RUNX3

2.35e-052169218663147
Pubmed

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses.

APC STAT3

2.35e-052169219701202
Pubmed

Requirement for dicer in survival of proliferating thymocytes experiencing DNA double-strand breaks.

RAG1 DICER1

2.35e-052169223427252
Pubmed

Coexpression of Runx1 and Runx3 in mechanoreceptive dorsal root ganglion neurons.

RUNX1 RUNX3

2.35e-052169223378040
Pubmed

Transcriptional cross-regulation of RUNX1 by RUNX3 in human B cells.

RUNX1 RUNX3

2.35e-052169215688019
Pubmed

RUNX3-mediated repression of RUNX1 in B cells.

RUNX1 RUNX3

2.35e-052169219603429
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FLNC RAP1GAP2 GBX2 CHD8 CEP192 INO80 ACOX3 PLEKHH3 CELSR1 EHBP1L1 RAB43 DUSP16 KCNQ2 TANC1 DHX34 HR RASD2

2.99e-0511051691735748872
Pubmed

Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair.

APC CHD8 GFAP

3.11e-0513169329920279
GeneFamilyImmunoglobulin like domain containing

FLT4 DSCAM CADM4 FCRLA NPTN TIE1 ALPK3

1.89e-041931117594
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2A

FLNC CACNB2 TGIF2 EPB41L4B CADM4 APC LAMA4 CHST6 ADGRG1 GFAP CELSR1 SCN1A KLHDC8A KCNQ2 ARAP2

6.93e-0660016615M39055
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KRT7 DCDC2 ANK2 TSPEAR RAP1GAP2 AGBL4 CELSR1 SCN9A CGNL1 PLCH1

3.51e-0919216910b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNC PDE1B FCRLA CCDC88B ACOX3 TYROBP TRABD KLHDC8A SP140

1.24e-081621699388670cf3acef17df971c0d8ae3ce14398945192
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNC PDE1B FCRLA CCDC88B ACOX3 TYROBP TRABD KLHDC8A SP140

1.24e-0816216999333d923225df7bfdf6b3a4c32816751315aec50
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DCDC2 TSPEAR RAP1GAP2 ADGRG1 CELSR1 SCN9A PLCH1 VWA2 ARAP2

3.57e-081831699c5b10571599dc26476170b54b53f09c23e6b3117
ToppCellfacs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE1B FCRLA RUNX3 CCDC88B ACOX3 OTOF RAB43 UBASH3B

3.50e-0717416986688424fc4e40c3c4a89669a2bc79369a726f1e6
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SPN NEK10 FSD1 RUNX2 TYROBP TANC1 ABCG2 UBASH3B

4.92e-071821698b86690c109cdc16844a6cd2216c1bf2bf28efd45
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

CACNB2 DPY19L2 ANK2 RAP1GAP2 ACOX3 AGBL4 TANC1 PRKAG2

6.29e-0718816986d249fe92d51a19da19ec14bb2262d394255d577
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DCDC2 EPB41L4B RAP1GAP2 ITGA2 ALPK3 PLCH1 VWA2 HDC

6.55e-0718916985d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT7 RAP1GAP2 ADGRG1 SORT1 KLHDC8A TANC1 CGNL1 INPP5J

6.82e-071901698c247562df3e1aa3173c9f01a74d5831f0764a1b2
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT7 RAP1GAP2 ADGRG1 SORT1 KLHDC8A TANC1 CGNL1 INPP5J

6.82e-0719016985cea8298c8336c136ba009630c9e48d4bc832cb2
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KRT7 DCDC2 TSPEAR RAP1GAP2 ADGRG1 CELSR1 SCN9A PLCH1

7.09e-07191169805731ece7867659c662f952812805f947032fe10
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

CACNB2 DPY19L2 ANK2 RAP1GAP2 AGBL4 ACOT11 TANC1 PRKAG2

7.09e-0719116985d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT4 ADGRG1 FAM117B RASIP1 TIE1 SCN9A TANC1 CX3CL1

7.38e-071921698c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KRT7 ANK2 DSCAM RAP1GAP2 ADGRG1 AGBL4 CELSR1 SCN9A

7.98e-071941698b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BACH1 USP24 APC ADGRG1 CEP170 NPTN LONRF3 UBASH3B

8.29e-071951698a1478021a3ed0e779716393124ca2a7770c433b7
ToppCellNon-neuronal-Postmitotic-Endothelial|World / Primary Cells by Cluster

DPEP1 FLT4 LAMA4 RASIP1 TIE1 ALPK3 ABCG2 CGNL1

9.66e-071991698b9763ac9857a60db6f1f104fe1e9ea2266cf931b
ToppCellNon-neuronal-Postmitotic-Endothelial-Endothelial-24|World / Primary Cells by Cluster

DPEP1 FLT4 LAMA4 RASIP1 TIE1 ALPK3 ABCG2 CGNL1

9.66e-0719916980b4edf3e359749827ef978a77b5267ddde732d71
ToppCellNon-neuronal-Postmitotic-Endothelial-Endothelial|World / Primary Cells by Cluster

DPEP1 FLT4 LAMA4 RASIP1 TIE1 ALPK3 ABCG2 CGNL1

9.66e-0719916989e01eee126247a0696c71b019f855a8a41a0ede3
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DPEP1 FLT4 LAMA4 RASIP1 TIE1 ABCG2 STRA6 VWA2

9.66e-071991698463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCellControl-Myeloid-Monocytes,_Macrophages-Mast-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPN NEK10 TYROBP KCNAB1 PACS2 PSRC1 HDC

2.57e-06159169781782e9e370558d61af5e0c760ac9759d69fb725
ToppCellfacs-Lung-EPCAM-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPN CD300A RAP1GAP2 RUNX2 TYROBP BRPF1 DUSP16

2.91e-061621697484ea4ac40de672dcbd2583a52cb7f385c918814
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPN CD300A RAP1GAP2 RUNX2 TYROBP BRPF1 DUSP16

2.91e-061621697bba144ac5332bab9eba2ccf599703c781a7f88f1
ToppCellcontrol-Epithelial-Ionocyte|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DPY19L2 ANK2 ZSCAN31 SCN9A CGNL1 DDX4 INPP5J

3.29e-0616516975cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCellcontrol-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DPY19L2 ANK2 ZSCAN31 SCN9A CGNL1 DDX4 INPP5J

3.70e-061681697327b02f19f4a8607c033203824fdc60a1254331f
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPN CD300A SMC6 RAP1GAP2 RUNX2 TYROBP DUSP16

3.70e-0616816974b5be7c6662eceddf90a65015f12908278d1664e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPN CD300A SMC6 RAP1GAP2 RUNX2 TYROBP DUSP16

3.70e-061681697689c41f6e9f65381570991cc311cba49a57ec955
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Intermediate|GW26 / Sample Type, Dataset, Time_group, and Cell type.

NEK10 FAM117B ACOT11 TNN PACS2 CGNL1

3.78e-06109169648f675d36fece070410eb9cfe64805f4629e290f
ToppCelldroplet-Lung-nan-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPN CD300A SMC6 RAP1GAP2 RUNX2 TYROBP DUSP16

3.85e-061691697ba023ee7bb165c2bfbefc2d969ff32ca1eeed33b
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPN CD300A BACH1 SMC6 RAP1GAP2 TYROBP DUSP16

3.85e-061691697411556e93adcbb7e4d79b02f3dc72963ec8a0759
ToppCelldroplet-Lung-nan-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPN CD300A SMC6 RAP1GAP2 RUNX2 TYROBP DUSP16

3.85e-061691697c96e0f3241d13926dbee9f91c0c8c5bfa7479a0d
ToppCelldroplet-Lung-LUNG-30m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPN CD300A BACH1 SMC6 RAP1GAP2 TYROBP DUSP16

3.85e-06169169739b1acfd099abb9de18c29c05c7a67709ea76775
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC FLT4 TSPEAR LAMA4 RASIP1 STARD9 HR

4.00e-0617016976035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC FLT4 TSPEAR LAMA4 RASIP1 STARD9 HR

4.00e-061701697c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC FLT4 TSPEAR LAMA4 RASIP1 STARD9 HR

4.00e-061701697dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DPEP1 FLT4 NEK10 TIE1 ABCG2 CGNL1 STRA6

4.32e-061721697c3a99828838af3b85c8c885d69cc8018f55ced50
ToppCelldroplet-Lung-LUNG-1m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPN CD300A SMC6 RAP1GAP2 RUNX2 TYROBP DUSP16

4.84e-061751697c8cfe0ac0c1ac447c626a623cc49692a0b177a1c
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPN CD300A SMC6 RAP1GAP2 RUNX2 TYROBP DUSP16

4.84e-06175169761fbd8f685d3daad46449e4c0386a38886496566
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1B FCRLA CCDC88B ACOX3 OTOF RAB43 UBASH3B

5.42e-0617816978c5e9fab7b55a654ccaabf2c4d02397399d94616
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCRT1 GARNL3 ANK2 MYT1 FSD1 AGBL4 SCN9A

6.04e-0618116977f99002a6411117cc2361334c7c9228e20c574b4
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 ASPG GRIN1 FCRLA VWA2 FGD6 SMTNL2

6.50e-061831697bc24145855bf4d027a8058bf92bc796c10f241bb
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG1 ASPG GRIN1 FCRLA VWA2 FGD6 SMTNL2

6.50e-0618316974c325ee6da070513097a11445ec95b0415ffd8a2
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DCDC2 EPB41L4B IRX6 ITGA2 AGBL4 PLCH1 VWA2

7.48e-061871697db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell11.5-Airway-Immune-Hematopoietic,_Natural_Killer_Cell|Airway / Age, Tissue, Lineage and Cell class

CRACR2A SPN CD300A ADGRG1 RUNX3 TYROBP SP140

7.48e-061871697bebb56d31a1df678d85a29931a2ec585549ac122
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC FLT4 TSPEAR LAMA4 RASIP1 TIE1 TMEM109

7.75e-061881697d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC FLT4 TSPEAR LAMA4 RASIP1 TIE1 TMEM109

7.75e-061881697524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DPEP1 FLT4 TIE1 ABCG2 CGNL1 STRA6 FGD6

8.02e-061891697f44ddb6cdbb406b0528a9b0ba3811183ab6d1fc6
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

FLNC CACNB2 DPY19L2 ANK2 ALPK3 TANC1 PRKAG2

8.02e-0618916970a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell3'_v3-bone_marrow-Lymphocytic_NK-NK_CD56bright_CD16-|bone_marrow / Manually curated celltypes from each tissue

CD300A RUNX2 RUNX3 CIRBP TYROBP TIE1 ARAP2

8.02e-0618916976e402fb3fc31e4cb541e3cd140d7a86c1083dbf5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 ANK2 MYT1 ACOT11 CGNL1 UBASH3B SMTNL2

8.30e-0619016971cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RUNX2 SCN9A KCNAB1 TANC1 UBASH3B PLCH1 INPP5J

8.30e-061901697d19bc44310c53726e2f5f6a2bd377bbbf1d1983f
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DCDC2 EPB41L4B RAP1GAP2 ITGA2 PLCH1 VWA2 HDC

8.30e-061901697625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC FLT4 ANK2 LAMA4 CELSR1 TIE1 ABCG2

8.30e-06190169726e2237f65cb43723c5da853831b40df2982d6e4
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

FLNC CACNB2 ANK2 ALPK3 TANC1 ABCG2 PRKAG2

8.30e-06190169793c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC FLT4 ANK2 LAMA4 CELSR1 TIE1 ABCG2

8.30e-061901697a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC FLT4 ANK2 LAMA4 CELSR1 TIE1 ABCG2

8.30e-0619016970bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DCDC2 NEK10 RAP1GAP2 CELSR1 SCN9A PLCH1 ARAP2

8.59e-06191169760ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DCDC2 EPB41L4B ITGA2 SCN1A PLCH1 VWA2 HDC

8.89e-061921697b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RUNX2 SCN9A KCNAB1 TANC1 UBASH3B PLCH1 INPP5J

9.19e-0619316974979862c0c16e6b4baa4c79894f1d237c861f5a5
ToppCellControl-NK_CD56bright|Control / Disease condition and Cell class

CD300A RUNX2 RUNX3 TYROBP CELSR1 TIE1 STARD9

9.19e-0619316978b1e7a226a6057e1097c1525984127b54e823876
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KRT7 DCDC2 TSPEAR RAP1GAP2 ADGRG1 CELSR1 SCN9A

9.19e-061931697aa10924b203c71e65fdbd2b90ba131dbd362d8b1
ToppCelldroplet-Heart-HEART-1m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC FLT4 MSH6 SCN1A CGNL1 STRA6 SMTNL2

9.19e-061931697d0a5f212f8e8a13dbbe3e41df92548ef82eef70b
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCRT1 CALCB CADM4 MYT1 SCN1A SCN9A KCNQ2

9.19e-06193169766af80f4b51e1ce97b6fb7c630dc5f95bfa7e7d4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPN CD300A RAP1GAP2 ADGRG1 RUNX3 TYROBP GTF3C1

9.19e-061931697b53ffef20f918b7d1e9d3924562691d13245e2dd
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DCDC2 EPB41L4B ITGA2 SCN1A PLCH1 VWA2 HDC

9.19e-0619316974b8202fcfe639a73f69a13f48fc3601ade256346
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

CACNB2 DPY19L2 ANK2 ACOX3 AGBL4 TANC1 PRKAG2

9.51e-06194169789812fb164065041357bb37a3c2d87028ec3de4e
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

KRT7 ZNF407 RCOR1 CELSR1 RBM6 TANC1 PPIP5K2

9.51e-06194169788db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

KRT7 ZNF407 RCOR1 CELSR1 RBM6 TANC1 PPIP5K2

9.51e-061941697a71728202493d4858342ea2756ea281cd0d99a3a
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPN CD300A ADGRG1 FSD1 RUNX3 TYROBP GTF3C1

9.83e-061951697acc603dc94ac6518adb0dffb43305b380ec75b52
ToppCell10x5'-lymph-node_spleen-Lymphocytic_NK-NK_CD16|lymph-node_spleen / Manually curated celltypes from each tissue

SPN CD300A RAP1GAP2 ADGRG1 RUNX3 TYROBP GTF3C1

1.02e-051961697f7e5a7fad4547e8ab9ab8b140239281832fb4260
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_dim-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPN CD300A ADGRG1 FSD1 RUNX3 TYROBP GTF3C1

1.02e-051961697c25f90c4e5abfe7cfaa85bfe136c438a5179c978
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_dim|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPN CD300A ADGRG1 FSD1 RUNX3 TYROBP GTF3C1

1.02e-051961697d451f279f4086fcf727af712f98923551181c76e
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT4 ZNF407 CEP170 RASIP1 TIE1 STARD9 PACS2

1.05e-051971697789c97ca9d1e28df3353140046047f11fbccc1d0
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_dim-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPN CD300A ADGRG1 FSD1 RUNX3 TYROBP GTF3C1

1.05e-05197169776304df40f87224f8e415677e3ee8fb183fe0c03
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPN CD300A ADGRG1 FSD1 RUNX3 TYROBP GTF3C1

1.05e-051971697300849a922722adcbc068593fc5cc0bef936d9cb
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KRT7 DPY19L2 DSCAM GFAP KLHDC8A SCN9A DDX4

1.05e-0519716978f009a15f154b3bb184b489da4722b7c27de7e11
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPN CD300A ADGRG1 FSD1 RUNX3 TYROBP GTF3C1

1.05e-051971697a97c4a9eb89260b0b5745834ccef9d558d857f93
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DPEP1 FLT4 LAMA4 RASIP1 TIE1 ABCG2 CX3CL1

1.09e-05198169772e8b9cccb7b0a2ea9d415218fff4fa2f09728f4
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE1B SPN CEP170 TYROBP ALPK3 KCNAB1 LONRF3

1.12e-051991697fde8e3ba19d19069a4d3b8db55bfe6220cf634d5
ToppCellSepsis-Int-URO-Myeloid-pDC|Int-URO / Disease, condition lineage and cell class

CADM4 SMC6 RUNX2 GUCY2D SCN9A SEC61B TMEM109

1.12e-051991697a41c3c3360b1b4546c9b2c49bda595feef6a4a4a
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DPEP1 FLT4 LAMA4 RASIP1 TIE1 ABCG2 VWA2

1.12e-0519916970602e2b2aa56d106da63bd342a38bef437b4d496
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DPEP1 FLT4 LAMA4 RASIP1 TIE1 ABCG2 STRA6

1.12e-05199169763c01e8961f48ed1bed4ab619cacf318cd6de7b9
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE1B SPN BACH1 CEP170 TYROBP ALPK3 LONRF3

1.12e-0519916975b6feacb0ca92c3fc6b327be978320426dcf6f68
ToppCellmLN-(0)_NK_cell-(00)_NK|mLN / shred on region, Cell_type, and subtype

CD300A ADGRG1 FSD1 RUNX2 RUNX3 TYROBP TIE1

1.12e-05199169759d8e4f57580c7273308c32e5308fc1d704b1f6d
ToppCellmLN-NK_cell-NK|mLN / Region, Cell class and subclass

CD300A ADGRG1 FSD1 RUNX2 RUNX3 TYROBP TIE1

1.12e-051991697cc9836b8d18edabe8849a3e948b84d954ef68c48
ToppCellmLN-NK_cell|mLN / Region, Cell class and subclass

CD300A ADGRG1 FSD1 RUNX2 RUNX3 TYROBP TIE1

1.12e-051991697dcc1d9a3f6f0e64f111d18386bfe5b154e9d5bbe
ToppCellmLN-(0)_NK_cell|mLN / shred on region, Cell_type, and subtype

CD300A ADGRG1 FSD1 RUNX2 RUNX3 TYROBP TIE1

1.12e-05199169705f5ae4c049f242131a7f59bcce4b18ed52f11be
ToppCellTransverse-B_cell-B_cell_cycling|B_cell / Region, Cell class and subclass

CRACR2A CEP192 ARHGAP11A RASIP1 TIE1 POLQ FGD6

1.12e-051991697170ae68963d31f3b821b6f0e8f0c039bea0bc981
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CALCB ANK2 CADM4 MYT1 FSD1 SCN9A KCNQ2

1.16e-05200169751d20543a9c9330c34c085d9290a1fc8b5bff0d4
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-NK-ILC|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SPN CD300A ADGRG1 FSD1 RUNX3 TYROBP GTF3C1

1.16e-05200169748131c7c9444af84afb23184382d82e850acb445
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SPN CD300A ADGRG1 FSD1 RUNX3 TYROBP GTF3C1

1.16e-052001697755d65be8f05d4bf37c5dbe54948d2d8ab357d30
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CD300A TYROBP CELSR1 SCN1A GUCY2D ALPK3

1.72e-051421696e5608bbbc04edcdaafe1affc4db7f9d8edba04d9
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPN RAP1GAP2 FCRLA RUNX2 RUNX3 TYROBP

2.63e-051531696c81a88d3f707487c511020d3960a1c41e706c6a0
ToppCelldroplet-Liver-Npc-21m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD35 CD300A KIF7 TYROBP INPP5J PADI1

2.73e-051541696d883b3e2a65e4375bea1216eb9bbc86c64ee449c
ToppCellfacs-Marrow-Granulocytes-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPB41L4B SNX33 IFT88 ALPK3 LONRF3 PPIP5K2

2.83e-051551696cd2f3ad4f131588325a667b6724e530d821fbe30
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 ARHGAP11A RASIP1 KLHDC8A POLQ PSRC1

2.83e-051551696969fc4c98a96bf2f436e8e63d4deb2183ef3b864
ToppCellfacs-Marrow-Granulocytes-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPB41L4B SNX33 IFT88 ALPK3 LONRF3 PPIP5K2

2.83e-0515516964246709e27703b94529369abbed5763e4002e79d
ToppCellfacs-Marrow-Granulocytes-3m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPB41L4B SNX33 IFT88 ALPK3 LONRF3 PPIP5K2

2.83e-0515516969b26ade19488511c72b64335011d2dcd81e8f167
ToppCellT_cells-GNLY+GZMB+_T_cells|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SPN CD300A RAP1GAP2 ADGRG1 RUNX3 ARAP2

3.04e-051571696e9eb56a1dd96bd2e9725a20f2cf70ddeab811bd6
ToppCellfacs-Lung-Endomucin-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPN CD300A RAP1GAP2 RUNX2 TYROBP DUSP16

3.04e-0515716960ad242320ada7bcb9e29548d3050bf4fd3a07115
ToppCellfacs-Lung-Endomucin-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPN CD300A RAP1GAP2 RUNX2 TYROBP DUSP16

3.04e-051571696fe4c9556806203e57522d1986754ebe5a20aa2de
DrugCefaclor [70356-03-5]; Up 200; 10.4uM; MCF7; HT_HG-U133A

CACNB2 BACH1 APC RCC1 RUNX1 EHBP1L1 PLCH1 CPLANE1 DHX34 INPP5J

1.87e-06194168104967_UP
DrugFluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; PC3; HT_HG-U133A

APC ADGRG1 ZNF407 ITGA2 RUNX1 ACOX3 RGS14 ACOT11 SCN1A DHX34

1.96e-06195168106691_UP
DrugPF-00539745-00 [351321-33-0]; Up 200; 10uM; PC3; HT_HG-U133A

FLT4 SPN IQSEC2 BACH1 RUNX1 RGS14 ALPK3 CCDC106 LONRF3 DHX34

2.15e-06197168105939_UP
DrugMethoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; MCF7; HT_HG-U133A

CACNB2 FLT4 TGIF2 USP24 ADGRG1 RUNX2 PLEKHH3 PACS2 PADI1 VCPIP1

2.25e-06198168102848_UP
DrugEthylnitrosourea

MYT1 APC DICER1 STAT3 MSH6 CELSR1 IFT88 OTOF KCNQ2 POLQ HR

1.13e-0529116811ctd:D005038
DrugPempidine tartrate [546-48-5]; Up 200; 13uM; PC3; HT_HG-U133A

CACNB2 IQSEC2 LAMA4 ADGRG1 ZNF407 RUNX1 PLCH1 DHX34 HR

1.57e-0519616894307_UP
DrugOxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; PC3; HT_HG-U133A

FLT4 LAMA4 RCC1 RUNX1 DICER1 RGS14 ACOT11 KCNAB1 PLCH1

1.57e-0519616895871_UP
DrugDebrisoquin sulfate [581-88-4]; Up 200; 9uM; PC3; HT_HG-U133A

APC ADGRG1 RCC1 GRIN1 RUNX1 ACOX3 EHBP1L1 ACOT11 PADI1

1.64e-0519716896688_UP
Drugtrifluoperazine dihydrochloride; Down 200; 10uM; PC3; HT_HG-U133A

ZSCAN31 SPN IQSEC2 RCC1 SH2B1 ACOX3 CCDC106 INPP5J PADI1

1.70e-0519816894448_DN
DrugEthotoin [86-35-1]; Up 200; 19.6uM; PC3; HT_HG-U133A

MYT1 IQSEC2 LAMA4 ZNF407 RCC1 STAT3 ACOT11 ABCG2 INPP5J

1.70e-0519816893809_UP
DiseaseBrugada Syndrome (disorder)

CACNB2 ANK2 HCN4 GPD1L

8.75e-06241634C1142166
DiseaseBrugada syndrome

CACNB2 HCN4 GPD1L

9.08e-0681633cv:C1142166
DiseaseOther specified cardiac arrhythmias

CACNB2 HCN4 GPD1L

2.64e-05111633C0348626
DiseaseNodal rhythm disorder

CACNB2 HCN4 GPD1L

2.64e-05111633C0264893
DiseaseEctopic rhythm

CACNB2 HCN4 GPD1L

2.64e-05111633C1399226
DiseaseCARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)

CACNB2 HCN4 GPD1L

2.64e-05111633C2748542
DiseaseEarly Infantile Epileptic Encephalopathy 6

SCN1A SCN9A

3.03e-0521632C4551549
DiseaseBrugada Syndrome 1

CACNB2 HCN4 GPD1L

4.54e-05131633C4551804
DiseaseSinus Node Dysfunction (disorder)

CACNB2 HCN4 GPD1L

7.17e-05151633C0428908
DiseaseProfound Mental Retardation

APC CHD8 KIF7 SNX14 SCN1A STRA6

1.27e-041391636C0020796
DiseaseMental Retardation, Psychosocial

APC CHD8 KIF7 SNX14 SCN1A STRA6

1.27e-041391636C0025363
DiseaseMental deficiency

APC CHD8 KIF7 SNX14 SCN1A STRA6

1.27e-041391636C0917816
DiseaseColorectal Carcinoma

DPEP1 FLNC CACNB2 ANK2 TSPEAR APC MSH6 MTRR ACIN1 ABCG2 VWA2 HDC HR

1.51e-0470216313C0009402
DiseaseNeurodevelopmental Disorders

ANK2 DSCAM IQSEC2 SCN1A KCNQ2

1.70e-04931635C1535926
Diseasesortilin measurement

SORT1 PSRC1

1.81e-0441632EFO_0600000
DiseaseIntellectual Disability

APC CHD8 GRIN1 KIF7 PNPT1 SNX14 SCN1A ACIN1 PACS2 STRA6

2.02e-0444716310C3714756
Diseasenervous system disorder

GFAP MTRR KCNQ2 ABCG2

2.13e-04531634C0027765
DiseaseMetastatic melanoma

FLT4 NEK10 GUCY2D ALPK3

2.29e-04541634C0278883
Diseasesick sinus syndrome (is_implicated_in)

ANK2 HCN4

3.00e-0451632DOID:13884 (is_implicated_in)
DiseaseTurcot syndrome (disorder)

APC MSH6

3.00e-0451632C0265325
DiseaseMilroy Disease

FLT4 CELSR1

3.00e-0451632C1704423
DiseaseEpilepsy

IQSEC2 GFAP SCN1A SCN9A KCNQ2

3.56e-041091635C0014544
DiseaseGilles de la Tourette syndrome (is_implicated_in)

HCN4 HDC

4.48e-0461632DOID:11119 (is_implicated_in)
Diseasecolorectal cancer (implicated_via_orthology)

APC SNX33 STAT3

6.02e-04301633DOID:9256 (implicated_via_orthology)
Diseaseresponse to angiotensin receptor blocker

CACNB2 DUSP16 PRKAG2

6.02e-04301633EFO_0010735
Diseasehereditary lymphedema (is_implicated_in)

CELSR1 TIE1

6.25e-0471632DOID:0050580 (is_implicated_in)
DiseaseCD5 antigen-like measurement

FCRLA RUNX3

6.25e-0471632EFO_0020248
Diseasehyperuricemia (implicated_via_orthology)

STAT3 ABCG2

6.25e-0471632DOID:1920 (implicated_via_orthology)
DiseaseOROFACIODIGITAL SYNDROME VI

KIF7 CPLANE1

6.25e-0471632C2745997
Diseasetea consumption measurement

MYT1 PLEKHH3 OR2W3 MSH6 ABCG2

7.67e-041291635EFO_0010091
Diseasecalcium measurement

DPEP1 WDR81 CHD8 AGBL4 RGS14 EHBP1L1 PIP5K1A CGNL1 UBASH3B PRKAG2 POLQ

7.73e-0462816311EFO_0004838
DiseaseEarly Childhood Epilepsy, Myoclonic

SCN1A SCN9A

8.31e-0481632C0393695
DiseaseIdiopathic Myoclonic Epilepsy

SCN1A SCN9A

8.31e-0481632C0338478
DiseaseSymptomatic Myoclonic Epilepsy

SCN1A SCN9A

8.31e-0481632C0338479
Diseaseplacental insufficiency (biomarker_via_orthology)

GRIN1 ITGA2

8.31e-0481632DOID:3891 (biomarker_via_orthology)
DiseaseBenign Infantile Myoclonic Epilepsy

SCN1A SCN9A

8.31e-0481632C0751120
DiseaseMyoclonic Encephalopathy

SCN1A SCN9A

8.31e-0481632C0438414
DiseaseMyoclonic Absence Epilepsy

SCN1A SCN9A

8.31e-0481632C0393703
Diseaseovarian cancer (implicated_via_orthology)

APC MSH6

8.31e-0481632DOID:2394 (implicated_via_orthology)
DiseaseAdenoma, Microcystic

APC MTRR ABCG2

1.03e-03361633C0205648
DiseaseAdenoma, Monomorphic

APC MTRR ABCG2

1.03e-03361633C0205649
DiseaseAdenoma, Basal Cell

APC MTRR ABCG2

1.03e-03361633C0205646
DiseaseFollicular adenoma

APC MTRR ABCG2

1.03e-03361633C0205647
DiseasePapillary adenoma

APC MTRR ABCG2

1.03e-03361633C0205650
DiseaseAdenoma, Trabecular

APC MTRR ABCG2

1.03e-03361633C0205651
DiseaseAdenoma

APC MTRR ABCG2

1.03e-03361633C0001430
DiseaseLynch Syndrome

APC MSH6

1.06e-0391632C4552100
DiseaseMyoclonic Epilepsy

SCN1A SCN9A

1.06e-0391632C0014550
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN9A

1.06e-0391632C3502809
DiseaseEpilepsy, Cryptogenic

IQSEC2 GFAP SCN1A KCNQ2

1.12e-03821634C0086237
DiseaseAwakening Epilepsy

IQSEC2 GFAP SCN1A KCNQ2

1.12e-03821634C0751111
DiseaseAura

IQSEC2 GFAP SCN1A KCNQ2

1.12e-03821634C0236018
Diseasediastolic blood pressure, systolic blood pressure

DPEP1 EFL1 CACNB2 ANK2 HCN4 NEK10 BACH1 AGBL4 PNPT1 MSH6 GUCY2D

1.30e-0367016311EFO_0006335, EFO_0006336
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN9A

1.33e-03101632DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN9A

1.33e-03101632DOID:0080422 (implicated_via_orthology)
DiseaseEpilepsy, Myoclonic, Infantile

SCN1A SCN9A

1.33e-03101632C0917800
Diseaselipoprotein-associated phospholipase A(2) measurement

GLCE ABCG2 PSRC1

1.41e-03401633EFO_0004746
DiseaseCopper-Overload Cirrhosis

KRT7 STAT3

1.61e-03111632C1876165
DiseaseMyoclonic Astatic Epilepsy

SCN1A SCN9A

1.61e-03111632C0393702
Diseaseimmunoglobulin isotype switching measurement

LAMA4 STAT3 RCOR1

1.86e-03441633EFO_0010128
Diseaseleft ventricular systolic function measurement

FLNC LUC7L2 ALPK3

1.86e-03441633EFO_0008206
Diseaseendometrial carcinoma (is_implicated_in)

APC RUNX3

1.93e-03121632DOID:2871 (is_implicated_in)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN9A

1.93e-03121632DOID:0060170 (implicated_via_orthology)
DiseaseTrigeminal Neuralgia

GRIN1 GFAP

1.93e-03121632C0040997
DiseaseSecondary Trigeminal Neuralgia

GRIN1 GFAP

1.93e-03121632C0393787
DiseaseTrigeminal Neuralgia, Idiopathic

GRIN1 GFAP

1.93e-03121632C0393786
DiseasePrecursor B-Cell Lymphoblastic Leukemia-Lymphoma

RUNX1 STAT3

1.93e-03121632C0023485
Diseaseepilepsy (implicated_via_orthology)

ANK2 SLC25A6 MINK1 SCN1A SCN9A

2.16e-031631635DOID:1826 (implicated_via_orthology)
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN9A

2.27e-03131632C0751122
Diseaseautosomal dominant polycystic kidney disease (implicated_via_orthology)

FLNC IFT88

2.64e-03141632DOID:898 (implicated_via_orthology)
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

DCDC2 GRXCR1 OTOF

2.84e-03511633cv:CN043650
Diseasecerebellar volume measurement

EFL1 APC ABCG2

3.00e-03521633EFO_0020864
DiseaseAlopecia, Male Pattern

SUPV3L1 HR

3.04e-03151632C4083212
DiseaseAndrogenetic Alopecia

SUPV3L1 HR

3.04e-03151632C0162311
DiseaseFemale pattern alopecia (disorder)

SUPV3L1 HR

3.04e-03151632C0263477
Diseasenon-alcoholic fatty liver disease, cirrhosis of liver

CRACR2A EHBP1L1 ZP4

3.17e-03531633EFO_0001422, EFO_0003095
Diseasecoronary thrombosis, GM11992

DSCAM EPB41L4B

3.46e-03161632EFO_0001124, EFO_1000883
Diseaseidiopathic scoliosis (implicated_via_orthology)

RUNX3 KIF7

3.46e-03161632DOID:0060250 (implicated_via_orthology)
Diseasecreatinine measurement

DPEP1 DCDC2 DSCAM DHX40 INO80 STAT3 RASIP1 RGS14 PIP5K1A ABCG2 CGNL1 PRKAG2 PLEKHH2

3.64e-0399516313EFO_0004518
DiseaseHypertrophic Cardiomyopathy

CACNB2 ALPK3 PRKAG2

3.89e-03571633C0007194
DiseaseAstrocytosis

ITGA2 GFAP

3.91e-03171632C3887640
Diseasecyclic adenosine monophosphate measurement

ABCG2 ARAP2

3.91e-03171632EFO_0010473
Diseaseulcerative colitis (is_implicated_in)

STAT3 MTRR

3.91e-03171632DOID:8577 (is_implicated_in)
DiseaseGliosis

ITGA2 GFAP

3.91e-03171632C0017639
Diseaseasthma, Eczema, allergic rhinitis

RUNX1 RUNX3 RGS14 RCOR1

4.62e-031211634EFO_0005854, HP_0000964, MONDO_0004979
DiseasePseudopelade

SUPV3L1 HR

4.88e-03191632C0086873
DiseaseJuvenile Myelomonocytic Leukemia

ZRSR2 RUNX1

4.88e-03191632C0349639
DiseaseAlopecia

SUPV3L1 HR

4.88e-03191632C0002170
Diseasesarcoidosis

FAM117B CCDC88B SP140

5.39e-03641633MONDO_0019338
DiseaseFamilial aplasia of the vermis

KIF7 CPLANE1

5.40e-03201632cv:C0431399

Protein segments in the cluster

PeptideGeneStartEntry
RGGRFTRSQEEARKS

ACIN1

336

Q9UKV3
STDVGSRADGRKFVQ

CEP170

996

Q5SW79
SRADGRKFVQSSGRI

CEP170

1001

Q5SW79
GIRFFSRSRKTSGLS

PRKAG2

146

Q9UGJ0
QKAFGTDRVRTGESS

BACH1

231

O14867
FARTRLAADVGKSGT

SLC25A6

136

P12236
AVSTAAAQFTKLRRG

CHD8

2231

Q9HCK8
ETLAGGQRRKLSSRF

CCDC88B

1386

A6NC98
TNVGSKAFGRRRRDL

CALCB

111

P10092
STRGNVFASVDTRKG

DDX4

686

Q9NQI0
KDVRQRFGASLGSLS

ACOX3

291

O15254
AGTAARRDSRGNEKT

DNM1P46

181

Q6ZS02
IAFARVFSGVARRGK

EFL1

506

Q7Z2Z2
QFIRGVSGGERKRTS

ABCG2

181

Q9UNQ0
GDGTQTAQRTRADRK

ALPK3

826

Q96L96
VFSNRTSRKSALRAG

ACOT11

16

Q8WXI4
SGGQRANRDGTKRSS

AMER1

346

Q5JTC6
RRSSSGFRVDGFEKR

GLCE

41

O94923
VGNSAVGKTSFLRRF

CRACR2A

551

Q9BSW2
TKGVSGSYFRERRNV

ARAP2

296

Q8WZ64
GDVGRVAALASRKSA

ANKRD35

31

Q8N283
SFSQKGREADSRGSQ

CEP72

216

Q9P209
ASEDKVSVRRGFRGC

CELSR1

1826

Q9NYQ6
RGDFSRNGKRTVFLV

DICER1

86

Q9UPY3
ARRKNRFKGSDGSTS

CACNB2

46

Q08289
EDARRAISRSGGFIK

RBM12B

51

Q8IXT5
SEGNESGNKLFRRFR

RAG1

961

P15918
VSGKRRGRNNAAASA

RCOR1

11

Q9UKL0
LKSRGSRGHVRFQDA

RCC1

231

P18754
ASGSRAKRISQLFRG

RASIP1

81

Q5U651
RTKGSGQQSERGSDR

RBM15B

616

Q8NDT2
SDSKRVRVFCARGGN

PADI1

206

Q9ULC6
QRFKTGAFSERQGST

RAB43

36

Q86YS6
GKRRRNRDGGTFISD

IWS1

541

Q96ST2
AVELSGAGRRKNATR

IRX6

141

P78412
GAGRRKNATRETTST

IRX6

146

P78412
ATAGDRLTEFRKGAQ

IRX6

276

P78412
SRAAALRAANKSGTG

INO80

476

Q9ULG1
DSGEKFNGSSQRRKR

ANK2

11

Q01484
EASVKNGGSSRVRIF

HDC

601

P19113
RIQSGEGRRKAFSTC

OR2A12

226

Q8NGT7
RIQSGEGRRKAFSTC

OR2A14

226

Q96R47
SFLFRAGVRAETNKG

LRCH3

611

Q96II8
RVAAKARVSATAGAR

MAGEB10

321

Q96LZ2
GTARDGDETRQRVKF

LUC7L

16

Q9NQ29
QRISGNTSRRGKSGF

HNRNPCL2

146

B2RXH8
SKVVQRGREFFDSNG

NGRN

271

Q9NPE2
AASEKGFGTRRVNIL

GRXCR1

86

A8MXD5
KASSQRLVSTGGRAA

GPR179

1981

Q6PRD1
RKVAQGSRSSLGARS

GUCY2D

521

Q02846
SNSFKASPERRNSGR

IZUMO1R

191

A6ND01
AFSGRGAQVRLSSAR

KRT7

16

P08729
TLTTFFGRRKSRQGS

SPN

341

P16150
FRGNRATKVDARRFA

ASPG

181

Q86U10
RNRRVAEAFARTGKT

GPD1L

271

Q8N335
RSLGRFEQLGKTAAS

FSD1

376

Q9BTV5
QRISGNTSRRGKSGF

HNRNPCL3

146

B7ZW38
ENTKLRRQSGFSVAG

KCNAB1

16

Q14722
GKRGRRNSVGSLDST

IQSEC2

1151

Q5JU85
RKHFRSSRGQEEISG

MTRR

151

Q9UBK8
TGRAREKAGFQEQSA

HR

631

O43593
NILKRSFSASGGERQ

NEK10

926

Q6ZWH5
FGDRSRARQAFRIKG

KCNQ2

486

O43526
KKRGRATDSFSGRFE

MKNK2

66

Q9HBH9
LQIRSASGRQKAFGT

OR2W3

226

Q7Z3T1
LASTFTQQARAKGRR

PDE1B

101

Q01064
NKANRFTVETRGAGT

FLNC

1366

Q14315
REANTKRSGVRAGEA

EHBP1L1

401

Q8N3D4
GVASRNAVAGRASKD

EHBP1L1

1206

Q8N3D4
AFQRKRRSGSNGSVV

KIF7

886

Q2M1P5
QRISGNTSRRGKSGF

HNRNPCL4

146

P0DMR1
NDRKGSVRALRATSG

PSRC1

151

Q6PGN9
GALNAGFKETRASER

GFAP

56

P14136
STRSEGKQAGRRGRS

PACS2

421

Q86VP3
RSQSKGRRGASLARE

DPY19L2

16

Q6NUT2
NKASARASREGGRAA

MSH6

21

P52701
GFSSRVTSRGLFKEN

ITGA2

706

P17301
KKFRSGSSFSRRAGS

PIP5K1A

461

Q99755
KSSTNGDCRRFRGSL

HCN4

86

Q9Y3Q4
QNRKTRTSFATDGGI

PLEKHH2

261

Q8IVE3
LRIQSGEGRRKAFST

OR2A5

226

Q96R48
GAAGSTTSTGKNRRR

GBX2

236

P52951
TAVRAAGFTKAALRG

IFT88

96

Q13099
GASEEGSASERRRQK

CCDC106

141

Q9BWC9
VKSRGALISAFSRDG

CPLANE1

251

Q9H799
SQERRGKQSVGRTFA

CGNL1

431

Q0VF96
KDGRIVQSRGLSSEF

FCRLA

211

Q7L513
KSTGSRFRNSVEGLN

FAM117B

336

Q6P1L5
DNGRKLRLGRQFSTS

POLQ

2166

O75417
RSREELGKVGSQSSF

DUSP16

641

Q9BY84
TSFNRDAVKAGTGRR

AGBL4

371

Q5VU57
ASTVRFRVDRKDDGG

CADM4

181

Q8NFZ8
RTLFQRTKGRSGEAE

ADGRG1

271

Q9Y653
RNTGSRAAFVKAVGF

CEP192

1916

Q8TEP8
KRRADFVAGSLSGRV

KLHDC8A

266

Q8IYD2
SQASAEQRKGRAGRT

DHX34

481

Q14147
SKSEALQRSGRAGRT

DHX40

386

Q8IX18
SSAGIRQAFREGKVA

DPEP1

121

P16444
GNSKSNRSDFIRLGS

EPB41L4B

371

Q9H329
ASAILSGSGRAQRKA

PKD1L1

2061

Q8TDX9
IFKAGAERSETRGAA

DCDC2

311

Q9UHG0
SSDADGAIQRAGRFR

GARNL3

51

Q5VVW2
RGDRIAKVTFRGQSF

OTOF

16

Q9HC10
RIQSGEGRRKAFSTC

OR2A1;

226

Q8NGT9
VADTSRRVGGALARK

LAMA4

691

Q16363
GTSRDGDTTRQRIKF

LUC7L2

16

Q9Y383
ERNDKVFFASVRSGG

MINK1

1301

Q8N4C8
AGDGVRSEQIFTRTK

DSCAM

1171

O60469
FNDLRFVGRSGRGKS

RUNX1

131

Q01196
RFVGRSGRGKSFTLT

RUNX2

186

Q13950
NDLRFVGRSGRGKSF

RUNX3

136

Q13761
GRGNDRREKLQSFDS

RBM6

1011

P78332
KRRQSVGDFVSGALN

ARHGAP11A

281

Q6P4F7
KRFSLRSVGRSVRGS

SH2B1

151

Q9NRF2
GSRGGRIFRSSDFAK

SORT1

191

Q99523
GGFLESFKRAIRVRS

RAP1GAP2

491

Q684P5
RDSLDQFSSSGKGAR

PLEKHH3

126

Q7Z736
DGRSRRKASNAGAAA

SCRT1

121

Q9BWW7
VNGTKRSSRRAGKAE

RIF1

1281

Q5UIP0
VLARGSKRETAFSRG

PPP1R32

256

Q7Z5V6
RFRGNLSGKRVDFSG

POLR3A

351

O14802
RTSLFSFKGRGRDIG

SCN9A

551

Q15858
RQDSLASAKRGSVVG

SNX33

166

Q8WV41
NTAGGRAQEVKARFA

TANC1

346

Q9C0D5
VQKTGFRSSGRFSDK

SPATA31E1

691

Q6ZUB1
KRRTGELRQFAGASE

STARD9

2676

Q9P2P6
QIAGRAGRFSSRFKE

SUPV3L1

466

Q8IYB8
RQSERGFREKTGALR

OVCA2

16

Q8WZ82
SAGSRAVAVDLGNRK

PNPT1

41

Q8TCS8
QLVRSFSRRTGAGSK

STRA6

226

Q9BX79
FTISRRGGKASDVAL

TGIF2

91

Q9GZN2
GKAALFVSNNSRRAR

PDXP

51

Q96GD0
RTSLFSFRGRAKDVG

SCN1A

571

P35498
VRETGANGTSFSVRK

BRPF1

426

P55201
GNSRGSKEARARASA

APC

371

P25054
GSAGKRNGRVSIRDS

CD300A

66

Q9UGN4
GPGARREAFKTSSRN

CHST6

311

Q9GZX3
QAGKSSDNRSRGYRG

CIRBP

81

Q14011
SRKTRGGEAALASAR

PRDM10-DT

86

Q96N53
GAASVGQTSARKRDA

INPP5J

226

Q15735
GRGAAEAATRKQRIT

TYROBP

71

O43914
GKAFSASNGLTRHRR

ZSCAN31

301

Q96LW9
IVRSFSSGKREGGDF

SMU1

431

Q2TAY7
AVAARAAGSTVRQRK

SEC61B

21

P60468
FRNTQKRGESFGISR

SNX14

491

Q9Y5W7
LVAFKGGRRSRNVST

TNN

1041

Q9UQP3
SGRVSRLAVKAAFFG

TRABD

326

Q9H4I3
CRVSTSGGQDSRRFK

TIE1

426

P35590
DSGDVAALRGSRKFN

STAT3

371

P40763
LFARFSKTEGGARRA

FLT4

981

P35916
KSRGQTSAANGLRAE

FGD6

706

Q6ZV73
GARKRRVTVNTAYGS

NPTN

81

Q9Y639
LRQAAERGFGSATRT

VWA2

426

Q5GFL6
GKSSIVSRFLNGRFE

RASD2

31

Q96D21
RARLKRSQSFGVASA

SMTNL2

336

Q2TAL5
RAVATNRGSSLKGFV

SMC6

96

Q96SB8
RKSFRRELGGTANAA

RGS14

241

O43566
DALGAAFATRSKAQR

VCPIP1

1181

Q96JH7
NRGKGRAATSFSLSD

PLCH1

1141

Q4KWH8
RLTGSRASGAQLEAK

TMEM109

201

Q9BVC6
GRIGREARFETTSGK

USP24

536

Q9UPU5
GTRFTQSDRAAQKRV

SP140

556

Q13342
LSVKGARFFVGSRRR

TSPEAR

191

Q8WU66
RARAQKALASTGGRS

UBASH3B

51

Q8TF42
RNVGSTFKDFRGSIS

ZNF407

321

Q9C0G0
GGSQRLFRKIGSRSS

PPIP5K2

206

O43314
GRGSQKDTRASANLR

GTF3C1

491

Q12789
DRTGSSFGKNSERRE

ZRSR2

351

Q15696
SFSVASASRPGRRNK

WDR81

691

Q562E7
ATRDVKNGSRGSVTR

ZP4

261

Q12836
KNGSRGSVTRDSIFR

ZP4

266

Q12836
RQAAALTRNGGTFEK

CX3CL1

91

P78423
ISTGKRDNEFSNSGR

ZNF527

156

Q8NB42
ADGRSVVDSIGKRRF

LONRF3

621

Q496Y0
ARRQKEGSLNGSSFS

MYT1

921

Q01538
FKRRRSSKDTSTGGG

GRIN1

891

Q05586