Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionrecombination hotspot binding

PRDM9 PRDM7

9.18e-062612GO:0010844
GeneOntologyMolecularFunctiontransition metal ion binding

ADCY10 TRAF4 ZMAT5 PRDM9 MYCBP2 KAT6A GATA4 HERC2 NOS1 TET3 CYP4A22 VDR

2.16e-0411896112GO:0046914
GeneOntologyMolecularFunctionhistone H3K14 acetyltransferase activity

KAT6A KAT6B

3.26e-049612GO:0036408
GeneOntologyMolecularFunctionzinc ion binding

TRAF4 ZMAT5 PRDM9 MYCBP2 KAT6A GATA4 HERC2 NOS1 TET3 VDR

3.39e-048916110GO:0008270
GeneOntologyMolecularFunctionhistone H3K36 methyltransferase activity

PRDM9 PRDM7

7.01e-0413612GO:0046975
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

KAT6A KAT6B

9.40e-0415612GO:0010484
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF607 ZNF277 ZNF629 GATA4 ZNF217 PRDM15 TET3 ZNF416 ZBTB14 ZNF121 VDR

1.23e-0312446111GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF607 ZNF277 ZNF629 GATA4 ZNF217 PRDM15 TET3 ZNF416 ZBTB14 ZNF121 VDR

1.46e-0312716111GO:0000987
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

PRDM9 PRDM7

1.68e-0320612GO:0042800
GeneOntologyBiologicalProcesspositive regulation of reciprocal meiotic recombination

PRDM9 PRDM7

5.14e-054612GO:0010845
GeneOntologyBiologicalProcessregulation of reciprocal meiotic recombination

PRDM9 PRDM7

5.14e-054612GO:0010520
GeneOntologyCellularComponentMOZ/MORF histone acetyltransferase complex

KAT6A KAT6B

1.69e-047602GO:0070776
GeneOntologyCellularComponentH3 histone acetyltransferase complex

KAT6A KAT6B

2.24e-048602GO:0070775
MousePhenoabnormal heart and great artery attachment

QSOX1 ADAM19 PCSK6 KAT6A GATA4 WDPCP ZBTB14

1.01e-05205527MP:0010426
MousePhenoabnormal heart and great vessel attachment

QSOX1 ADAM19 PCSK6 KAT6A GATA4 WDPCP ZBTB14

1.11e-05208527MP:0010425
MousePhenocommon ventricle

PCSK6 KAT6A GATA4

1.35e-0513523MP:0010432
MousePhenoatrioventricular septal defect

QSOX1 KAT6A GATA4 WDPCP ZBTB14

1.45e-0584525MP:0010412
MousePhenoabnormal truncus arteriosus septation

QSOX1 ADAM19 PCSK6 GATA4 WDPCP

1.45e-0584525MP:0010454
MousePhenoabnormal atrioventricular septum morphology

QSOX1 KAT6A GATA4 WDPCP ZBTB14

1.72e-0587525MP:0010592
MousePhenoabnormal aorticopulmonary septum morphology

QSOX1 ADAM19 PCSK6 WDPCP

1.16e-0468524MP:0010650
MousePhenoaorticopulmonary septal defect

QSOX1 ADAM19 PCSK6 WDPCP

1.16e-0468524MP:0010651
MousePhenoabnormal heart ventricle morphology

FBLN5 ADAM19 PCSK6 KAT6A GATA4 PRDM15 NOS1 ZNF416 WDPCP ZBTB14 VDR

1.30e-047935211MP:0005294
MousePhenoabnormal cardiac outflow tract development

QSOX1 ADAM19 PCSK6 GATA4 WDPCP

1.36e-04134525MP:0006126
MousePhenoatrial septal defect

ADAM19 PCSK6 KAT6A GATA4

3.15e-0488524MP:0010403
DomainEGF-like_dom

NELL2 SCUBE1 FBLN5 ADAM19 MALRD1 SCUBE2 ZAN ADAM21 MATN2 PCSK6 LTBP2

3.02e-102495911IPR000742
DomainEGF_3

NELL2 SCUBE1 FBLN5 ADAM19 MALRD1 SCUBE2 ZAN ADAM21 MATN2 LTBP2

3.01e-092355910PS50026
DomainEGF_1

NELL2 SCUBE1 FBLN5 ADAM19 MALRD1 SCUBE2 ZAN ADAM21 LTBP2 USH2A

6.59e-092555910PS00022
DomainEGF-like_CS

NELL2 SCUBE1 FBLN5 ADAM19 MALRD1 SCUBE2 ZAN ADAM21 MATN2 LTBP2

8.23e-092615910IPR013032
DomainEGF_2

NELL2 SCUBE1 FBLN5 ADAM19 MALRD1 SCUBE2 ZAN ADAM21 MATN2 LTBP2

9.51e-092655910PS01186
DomainEGF

NELL2 SCUBE1 FBLN5 MALRD1 SCUBE2 ZAN MATN2 PCSK6 LTBP2

4.93e-08235599SM00181
DomainEGF_CA

NELL2 SCUBE1 FBLN5 SCUBE2 MATN2 LTBP2

2.96e-0786596PF07645
DomainGrowth_fac_rcpt_

NELL2 SCUBE1 FBLN5 SCUBE2 MATN2 PCSK6 LTBP2

5.87e-07156597IPR009030
DomainASX_HYDROXYL

NELL2 SCUBE1 FBLN5 SCUBE2 MATN2 LTBP2

7.25e-07100596PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

NELL2 SCUBE1 FBLN5 SCUBE2 MATN2 LTBP2

1.02e-06106596IPR000152
DomaincEGF

SCUBE1 FBLN5 SCUBE2 MATN2

1.27e-0626594IPR026823
DomaincEGF

SCUBE1 FBLN5 SCUBE2 MATN2

1.27e-0626594PF12662
DomainEGF_CA

NELL2 SCUBE1 FBLN5 SCUBE2 MATN2 LTBP2

2.33e-06122596SM00179
DomainEGF-like_Ca-bd_dom

NELL2 SCUBE1 FBLN5 SCUBE2 MATN2 LTBP2

2.56e-06124596IPR001881
DomainSecretoglobin_1C1/2

SCGB1C2 SCGB1C1

9.81e-062592IPR028659
DomainEGF_Ca-bd_CS

NELL2 SCUBE1 FBLN5 SCUBE2 LTBP2

1.37e-0597595IPR018097
DomainEGF_CA

NELL2 SCUBE1 FBLN5 SCUBE2 LTBP2

1.51e-0599595PS01187
DomainZINC_FINGER_C2H2_2

PRDM9 KIN ZNF607 ZNF277 ZNF629 ZNF217 PRDM7 PRDM15 ZNF416 ZBTB14 ZNF121

2.65e-057755911PS50157
DomainZINC_FINGER_C2H2_1

PRDM9 KIN ZNF607 ZNF277 ZNF629 ZNF217 PRDM7 PRDM15 ZNF416 ZBTB14 ZNF121

2.71e-057775911PS00028
DomainZnF_C2H2

PRDM9 KIN ZNF607 ZNF277 ZNF629 ZNF217 PRDM7 PRDM15 ZNF416 ZBTB14 ZNF121

3.88e-058085911SM00355
DomainEGF

MALRD1 SCUBE2 ZAN MATN2 LTBP2

4.83e-05126595PF00008
Domainzf-C2H2

PRDM9 ZNF607 ZNF277 ZNF629 ZNF217 PRDM7 PRDM15 ZNF416 ZBTB14 ZNF121

5.62e-056935910PF00096
DomainMOZ_SAS

KAT6A KAT6B

9.75e-055592PF01853
DomainHAT_MYST-type

KAT6A KAT6B

9.75e-055592IPR002717
DomainMYST_HAT

KAT6A KAT6B

9.75e-055592PS51726
DomainZnf_C2H2-like

PRDM9 KIN ZNF607 ZNF277 ZNF629 ZNF217 PRDM15 ZNF416 ZBTB14 ZNF121

1.76e-047965910IPR015880
DomainZnf_C2H2

PRDM9 ZNF607 ZNF277 ZNF629 ZNF217 PRDM7 PRDM15 ZNF416 ZBTB14 ZNF121

1.93e-048055910IPR007087
DomainAPC_su10/DOC_dom

MYCBP2 HERC2

2.04e-047592IPR004939
DomainDOC

MYCBP2 HERC2

2.04e-047592PS51284
DomainAPC10

MYCBP2 HERC2

2.04e-047592SM01337
DomainANAPC10

MYCBP2 HERC2

2.04e-047592PF03256
DomainSSXRD

PRDM9 PRDM7

2.71e-048592PF09514
DomainSSXRD_motif

PRDM9 PRDM7

2.71e-048592IPR019041
DomainSCGB

SCGB1C2 SCGB1C1

3.48e-049592PS51311
DomainSET

PRDM9 PRDM7 PRDM15

4.13e-0446593SM00317
DomainUteroglobin

SCGB1C2 SCGB1C1

4.34e-0410592PF01099
DomainSET_dom

PRDM9 PRDM7 PRDM15

5.28e-0450593IPR001214
DomainSET

PRDM9 PRDM7 PRDM15

5.28e-0450593PS50280
DomainKRAB_RELATED

PRDM9 PRDM7

5.30e-0411592PS50806
DomainEphrin_rec_like

SCUBE1 SCUBE2

5.30e-0411592PF07699
DomainSecretoglobin

SCGB1C2 SCGB1C1

5.30e-0411592IPR016126
DomainEGF_3

SCUBE1 SCUBE2

6.34e-0412592PF12947
DomainEGF_dom

SCUBE1 SCUBE2

6.34e-0412592IPR024731
DomainH15

KAT6A KAT6B

7.48e-0413592SM00526
DomainH15

KAT6A KAT6B

7.48e-0413592PS51504
DomainKrueppel-associated_box-rel

PRDM9 PRDM7

7.48e-0413592IPR003655
DomainHistone_H1/H5_H15

KAT6A KAT6B

8.71e-0414592IPR005818
DomainEGF_extracell

NELL2 ADAM19 LTBP2

9.02e-0460593IPR013111
DomainEGF_2

NELL2 ADAM19 LTBP2

9.02e-0460593PF07974
DomainDisintegrin_CS

ADAM19 ADAM21

1.14e-0316592IPR018358
Domain-

PRDM9 ZNF607 ZNF629 ZNF217 PRDM15 ZNF416 ZBTB14 ZNF121

1.26e-036795983.30.160.60
DomainMAM

MALRD1 ZAN

1.29e-0317592SM00137
DomainZnf_C2H2/integrase_DNA-bd

PRDM9 ZNF607 ZNF629 ZNF217 PRDM15 ZNF416 ZBTB14 ZNF121

1.45e-03694598IPR013087
DomainMAM

MALRD1 ZAN

1.45e-0318592PF00629
DomainMAM_dom

MALRD1 ZAN

1.45e-0318592IPR000998
DomainMAM_2

MALRD1 ZAN

1.45e-0318592PS50060
DomainADAM_CR

ADAM19 ADAM21

1.45e-0318592PF08516
Domain-

MYCBP2 PCSK6 HERC2

1.59e-03735932.60.120.260
DomainVWC_out

NELL2 ZAN

1.62e-0319592SM00215
DomainPDEase

PDE8A PDE5A

1.62e-0319592IPR023088
Domain-

ADAM19 ADAM21

1.80e-03205924.10.70.10
DomainRCC1

MYCBP2 HERC2

1.80e-0320592PF00415
DomainPDEase_I

PDE8A PDE5A

1.98e-0321592PF00233
DomainRCC1_1

MYCBP2 HERC2

1.98e-0321592PS00625
DomainRCC1_2

MYCBP2 HERC2

1.98e-0321592PS00626
DomainDisintegrin

ADAM19 ADAM21

1.98e-0321592PF00200
DomainRCC1_3

MYCBP2 HERC2

1.98e-0321592PS50012
DomainPDEASE_I

PDE8A PDE5A

1.98e-0321592PS00126
DomainPDEase_CS

PDE8A PDE5A

1.98e-0321592IPR023174
DomainDISIN

ADAM19 ADAM21

1.98e-0321592SM00050
DomainReg_chr_condens

MYCBP2 HERC2

2.18e-0322592IPR000408
Domain-

MYCBP2 HERC2

2.18e-03225922.130.10.30
Domain-

PDE8A PDE5A

2.18e-03225921.10.1300.10
DomainPDEase_catalytic_dom

PDE8A PDE5A

2.38e-0323592IPR002073
DomainRCC1/BLIP-II

MYCBP2 HERC2

2.38e-0323592IPR009091
DomainHDc

PDE8A PDE5A

2.59e-0324592SM00471
DomainHD/PDEase_dom

PDE8A PDE5A

2.59e-0324592IPR003607
DomainEphrin_rec_like

SCUBE1 SCUBE2

2.81e-0325592SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

SCUBE1 SCUBE2

2.81e-0325592IPR011641
DomainACR

ADAM19 ADAM21

3.27e-0327592SM00608
PathwayWP_PHOSPHODIESTERASES_IN_NEURONAL_FUNCTION

ADCY10 PDE8A PDE5A NOS1

3.00e-0555464M39763
Pubmed

SCGB1C1 Plays a Critical Role in Suppression of Allergic Airway Inflammation through the Induction of Regulatory T Cell Expansion.

SCGB1C2 SCGB1C1

3.03e-06261238892470
Pubmed

FBLN5 was Regulated by PRDM9, and Promoted Senescence and Osteogenic Differentiation of Human Periodontal Ligament Stem Cells.

PRDM9 FBLN5

3.03e-06261237608663
Pubmed

Latent TGF-beta-binding protein 2 binds to DANCE/fibulin-5 and regulates elastic fiber assembly.

FBLN5 LTBP2

3.03e-06261217581631
Pubmed

Regulation of KAT6 Acetyltransferases and Their Roles in Cell Cycle Progression, Stem Cell Maintenance, and Human Disease.

KAT6A KAT6B

3.03e-06261227185879
Pubmed

ZFP217 regulates adipogenesis by controlling mitotic clonal expansion in a METTL3-m6A dependent manner.

METTL3 ZNF217

3.03e-06261231434544
Pubmed

ERα status of invasive ductal breast carcinoma as a result of regulatory interactions between lysine deacetylases KAT6A and KAT6B.

KAT6A KAT6B

3.03e-06261239505971
Pubmed

The double PHD finger domain of MOZ/MYST3 induces α-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.

KAT6A KAT6B

3.03e-06261224150941
Pubmed

MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain.

KAT6A KAT6B

9.07e-06361236754959
Pubmed

The relationship of serum SCUBE-1, -2 and -3 levels with clinical findings and ultrasonographic skin thickness in systemic sclerosis patients.

SCUBE1 SCUBE2

9.07e-06361231991528
Pubmed

Identification of a novel family of cell-surface proteins expressed in human vascular endothelium.

SCUBE1 SCUBE2

9.07e-06361212270931
Pubmed

Phosphodiesterase-5A dysregulation in penile erectile tissue is a mechanism of priapism.

PDE5A NOS1

9.07e-06361215668387
Pubmed

LTBP-2 competes with tropoelastin for binding to fibulin-5 and heparin, and is a negative modulator of elastinogenesis.

FBLN5 LTBP2

9.07e-06361224148803
Pubmed

Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin.

KAT6A KAT6B

9.07e-06361223063713
Pubmed

The gain-of-function GLI1 transcription factor TGLI1 enhances expression of VEGF-C and TEM7 to promote glioblastoma angiogenesis.

VEGFC PLXDC1

9.07e-06361226093087
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

QSOX1 NELL2 FBLN5 ZNF277 MATN2 KAT6A FHL2 KAT6B

1.09e-0560861816713569
Pubmed

The interaction of ETV6 (TEL) and TIP60 requires a functional histone acetyltransferase domain in TIP60.

KAT6A KAT6B

1.81e-05461217980166
Pubmed

Recognition of unmodified histone H3 by the first PHD finger of bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases monocytic leukemic zinc-finger protein (MOZ) and MOZ-related factor (MORF).

KAT6A KAT6B

1.81e-05461221880731
Pubmed

Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes.

PRDM9 PRDM7

1.81e-05461218231586
Pubmed

Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replication.

KAT6A KAT6B

3.02e-05561217182677
Pubmed

Scube3 is expressed in multiple tissues during development but is dispensable for embryonic survival in the mouse.

SCUBE1 SCUBE2

3.02e-05561223383134
Pubmed

Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways.

SCGB1C2 SCGB1C1

3.02e-05561212406855
Pubmed

MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2.

KAT6A KAT6B

3.02e-05561211965546
Pubmed

FHL2 inhibits the activated osteoclast in a TRAF6-dependent manner.

TRAF4 FHL2

3.02e-05561216184196
Pubmed

Simultaneous dystrophin and dysferlin deficiencies associated with high-level expression of the coxsackie and adenovirus receptor in transgenic mice.

DYSF NOS1

3.02e-05561217148677
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

ZMAT5 PCSK6 MKRN2 ZNF217 FHL2 KAT6B ZBTB14 VDR

3.26e-0570961822988430
Pubmed

Mesodermal expression of Moz is necessary for cardiac septum development.

KAT6A GATA4

6.32e-05761225912687
Pubmed

Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.

KAT6A KAT6B

6.32e-05761218794358
Pubmed

The yin-yang of PR-domain family genes in tumorigenesis.

PRDM9 PRDM7

6.32e-05761210668202
Pubmed

Disruption of Scube2 Impairs Endochondral Bone Formation.

SCUBE1 SCUBE2

6.32e-05761225639508
Pubmed

Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling.

MYCBP2 HERC2

6.32e-05761236700049
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

VEGFC QSOX1 FBLN5 MATN2 LTBP2

7.61e-0524861524006456
Pubmed

SET domains and histone methylation.

PRDM9 PRDM7

8.42e-05861214675547
Pubmed

Genetic modifiers of muscular dystrophy: implications for therapy.

DYSF NOS1

1.08e-04961216916601
Pubmed

Acetylation of HIV-1 integrase by p300 regulates viral integration.

KAT6A KAT6B

1.65e-041161216096645
Pubmed

Chromosomal assignment of four testis-expressed mouse genes from a new family of transmembrane proteins (ADAMs) involved in cell-cell adhesion and fusion.

GATA4 NOS1

1.97e-04126128786143
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

FBLN5 ADAM19 MATN2 LTBP2

2.16e-0416761422159717
Pubmed

Detection of novel skeletogenesis target genes by comprehensive analysis of a Runx2(-/-) mouse model.

PDE8A PCSK6 VDR

2.70e-047161316829211
Pubmed

Inhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytes.

PDE8A PDE5A

2.72e-041461225852085
Pubmed

Parathyroid hormone regulates fetal-placental mineral homeostasis.

LYPD8 VDR

3.13e-041561219968565
Pubmed

Tet proteins influence the balance between neuroectodermal and mesodermal fate choice by inhibiting Wnt signaling.

GATA4 TET3

3.13e-041561227930333
Pubmed

Identification and initial characterization of 5000 expressed sequenced tags (ESTs) each from adult human normal and osteoarthritic cartilage cDNA libraries.

SCUBE1 ZNF277

3.13e-041561211597177
Pubmed

Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA Transcription Factor Binding and Disrupts Conduction System Development and Function.

GALNT10 GATA4

3.13e-041561231366290
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

QSOX1 NELL2 FBLN5 MYCBP2 FHL2 VPS51

4.45e-0456061621653829
Pubmed

Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation.

METTL3 GATA4

4.55e-041861225569111
Pubmed

SCUBE3 loss-of-function causes a recognizable recessive developmental disorder due to defective bone morphogenetic protein signaling.

SCUBE1 SCUBE2

4.55e-041861233308444
Pubmed

MOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndrome.

KAT6A GATA4

5.63e-042061222921202
Pubmed

Analyses of associations with asthma in four asthma population samples from Canada and Australia.

NOS1 VDR SPINK5

5.77e-049261319247692
Pubmed

Wdpcp promotes epicardial EMT and epicardium-derived cell migration to facilitate coronary artery remodeling.

VEGFC WDPCP

6.22e-042161229487191
Pubmed

m6A epitranscriptomic modification regulates neural progenitor-to-glial cell transition in the retina.

TRAF4 METTL3

6.83e-042261236459087
Pubmed

Ets1 is required for proper migration and differentiation of the cardiac neural crest.

ADAM19 GATA4

6.83e-042261220356956
Pubmed

Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis.

PRDM9 PRDM15

6.83e-042261219050759
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

QSOX1 PCSK6 ZBTB14

7.35e-0410061325807483
Pubmed

KLF13 is a genetic modifier of the Holt-Oram syndrome gene TBX5.

VEGFC GATA4

7.48e-042361228164238
Pubmed

Klf14 is an imprinted transcription factor that regulates placental growth.

FBLN5 LTBP2

7.48e-042361231675530
Pubmed

Proteomics characterization of extracellular space components in the human aorta.

FBLN5 MATN2 LTBP2

7.57e-0410161320551380
Pubmed

HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development.

KAT6A GATA4

8.15e-042461221149574
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ZNF629 HERC2 KAT6B

8.24e-041046139205841
Pubmed

Overview of PDEs and their regulation.

PDE8A PDE5A

8.84e-042561217307970
Pubmed

A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation.

PRDM9 GATA4

8.84e-042561225611385
Pubmed

Replication of genetic association studies in asthma and related phenotypes.

NOS1 SPINK5

9.57e-042661220395963
Pubmed

Unconventional myosin VI in the heart: Involvement in cardiac dysfunction progressing with age.

GATA4 DYSF

1.03e-032761237169038
Pubmed

Nodal specifies embryonic visceral endoderm and sustains pluripotent cells in the epiblast before overt axial patterning.

PCSK6 GATA4

1.11e-032861216728477
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

NELL2 MATN2 PCSK6

1.19e-0311861321078624
Pubmed

Ovol2/Movo, a homologue of Drosophila ovo, is required for angiogenesis, heart formation and placental development in mice.

VEGFC GATA4

1.19e-032961217573777
Pubmed

Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity.

MYCBP2 GATA4

1.36e-033161227321927
Pubmed

Transcriptional Architecture of Synaptic Communication Delineates GABAergic Neuron Identity.

PDE5A NOS1

1.36e-033161228942923
Cytoband1q24

ADCY10 QSOX1

3.14e-04206021q24
GeneFamilyZinc fingers C2H2-type|PR/SET domain family

PRDM9 PRDM7 PRDM15

1.02e-05174631197
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

PRDM9 ZNF607 ZNF629 ZNF217 PRDM7 PRDM15 ZNF416 ZBTB14 ZNF121

6.88e-0571846928
GeneFamilySecretoglobins

SCGB1C2 SCGB1C1

5.65e-0414462734
GeneFamilyZinc fingers C2HC-type|PHD finger proteins|Lysine acetyltransferases

KAT6A KAT6B

7.43e-041646266
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

KAT6A KAT6B

8.41e-0417462486
GeneFamilyPhosphodiesterases

PDE8A PDE5A

1.69e-0324462681
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ADAM19 ADAM21

2.13e-032746247
CoexpressionNABA_MATRISOME

VEGFC NELL2 SCUBE1 FBLN5 ADAM19 SCUBE2 PLXDC1 ADAM21 MATN2 PCSK6 LTBP2 USH2A

3.60e-0610266112M5889
CoexpressionNABA_MATRISOME

VEGFC NELL2 SCUBE1 FBLN5 ADAM19 SCUBE2 PLXDC1 ADAM21 MATN2 PCSK6 LTBP2

1.85e-0510086111MM17056
CoexpressionENK_UV_RESPONSE_EPIDERMIS_DN

NELL2 ZNF277 MATN2 ZNF217 HERC2 FHL2 KAT6B SPINK5

2.38e-05512618M4508
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

NELL2 SCUBE1 SCUBE2 PDE8A MYCBP2 GATA4 DYSF

6.95e-05438617M1954
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

NELL2 SCUBE1 SCUBE2 PDE8A MYCBP2 GATA4 DYSF

7.15e-05440617MM832
CoexpressionNABA_ECM_GLYCOPROTEINS

NELL2 FBLN5 MATN2 LTBP2 USH2A

9.41e-05196615M3008
CoexpressionGSE23321_CD8_STEM_CELL_MEMORY_VS_EFFECTOR_MEMORY_CD8_TCELL_UP

TRAF4 METTL3 PDE8A ADAM21 KAT6B

1.01e-04199615M8429
CoexpressionGSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_DN

ZMAT5 ZNF217 HERC2 VPS51 DYSF

1.01e-04199615M8861
CoexpressionGSE41978_WT_VS_ID2_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN

FBLN5 ADAM19 PDE8A FHL2 CYP4A22

1.03e-04200615M9549
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_200

SCUBE1 PLXDC1 MATN2 GATA4

3.98e-0723574gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_500

SCUBE1 PLXDC1 MATN2 GATA4

7.00e-0646574gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k3_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500

SCUBE1 PLXDC1 MATN2 GATA4

1.15e-0552574gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k2_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_500

SCUBE1 PLXDC1 MATN2 GATA4

1.90e-0559574gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k3_500
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_500

SCUBE1 PLXDC1 MATN2 PCSK6 GATA4

1.98e-05123575gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k3_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_500

SCUBE1 PLXDC1 MATN2 GATA4

2.17e-0561574gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k3_500
CoexpressionAtlasdev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000

QSOX1 SCUBE1 PLXDC1 ZNF277 MATN2 PCSK6 GATA4 TEX15 KAT6B NOS1

4.87e-058035710gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_1000
CoexpressionAtlasdev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_200

PLXDC1 ZNF277 MATN2 GATA4 TEX15

9.53e-05171575gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_200
CoexpressionAtlasdev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500

NELL2 SCUBE1 PLXDC1 ZNF277 MATN2 GATA4 TEX15

9.98e-05404577gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000

QSOX1 SCUBE1 PLXDC1 ZNF277 MATN2 PCSK6 GATA4 TEX15 KAT6B

1.45e-04740579gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_500

SCUBE1 PLXDC1 ZNF277 MATN2 PCSK6 GATA4 TEX15

1.51e-04432577gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_1000

PLXDC1 ZNF277 MATN2 GATA4 KAT6B

1.60e-04191575gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_1000

SCUBE1 PLXDC1 PCSK6 GATA4

2.34e-04112574gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k1_1000
CoexpressionAtlasdev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000

NELL2 SCUBE1 PLXDC1 ZNF277 MATN2 PCSK6 GATA4 TEX15 KAT6B

2.39e-04791579gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_1000

SCUBE1 PLXDC1 ZNF277 MATN2 PCSK6 GATA4 TEX15 KAT6B NOS1

2.52e-04797579gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_1000

SCUBE1 PLXDC1 MATN2 GATA4

2.85e-04118574gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_500

SCUBE1 PLXDC1 GATA4

2.91e-0448573gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k1_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

SCUBE1 PLXDC1 MATN2 GATA4

3.55e-04125574gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k1_1000
CoexpressionAtlasdev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#2_top-relative-expression-ranked_1000

SCUBE1 PLXDC1 GATA4

4.84e-0457573gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k2_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_200

SCUBE1 PLXDC1 MATN2 GATA4

5.17e-04138574gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_200
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_500

SCUBE1 PLXDC1 ZNF277 MATN2 GATA4 TEX15

5.68e-04385576gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_200

SCUBE1 PLXDC1 MATN2 GATA4

6.38e-04146574gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_200
CoexpressionAtlasdev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_1000

SCUBE1 PLXDC1 ZNF277 GATA4 KAT6B

6.48e-04259575gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k1_1000
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

VEGFC SCGB1C2 PCSK6 PDE5A FHL2 SCGB1C1

1.91e-071866063bf38c80d892a73391009b426dec8ae26a027351
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

VEGFC SCGB1C2 PCSK6 PDE5A FHL2 SCGB1C1

1.91e-07186606107bc473f5e57238390f8e0ab9f7263a8f93948c
ToppCellPBMC-Control-Hematopoietic-Platelet|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

VEGFC SCGB1C2 PCSK6 PDE5A FHL2 SCGB1C1

1.91e-071866067496137cebc191aecd1e6ae7fa33118b128fbfe6
ToppCellPBMC-Control-Hematopoietic-Platelet|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

VEGFC SCGB1C2 PCSK6 PDE5A FHL2 SCGB1C1

1.91e-071866069c2fd0bbc968c317a763f52e72fa7182c3c49850
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

VEGFC SCGB1C2 PCSK6 PDE5A FHL2 SCGB1C1

1.91e-0718660613a9ddcf93b0c4319ab9d484af5e2056e9754caa
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

VEGFC SCGB1C2 PCSK6 PDE5A FHL2 SCGB1C1

1.91e-0718660606281df5e9665ccc510279bf7e552845c63d5dab
ToppCellHealthy_donor-Platelet|Healthy_donor / disease group, cell group and cell class (v2)

VEGFC SCGB1C2 PCSK6 PDE5A FHL2 SCGB1C1

1.98e-071876069040ffa5c23913b9dc0205fa6227223c2a2847ae
ToppCell368C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

QSOX1 FBLN5 KCTD16 PDE5A LTBP2 KAT6B

2.45e-07194606d9eec28fa7b255c0ec023276dd955f1e276e7159
ToppCell368C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

QSOX1 FBLN5 KCTD16 PDE5A LTBP2 KAT6B

2.45e-07194606e4d7e9709ce42d4610e44d3445927eefbcbb9eff
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBLN5 PLXDC1 MATN2 PDE5A LTBP2 FHL2

2.61e-07196606fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBLN5 PLXDC1 MATN2 PDE5A LTBP2 FHL2

2.61e-07196606802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-thrombocytic|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

VEGFC PCSK6 PDE5A FHL2 SCGB1C1

3.55e-061726051a9b99c7fc297d9e4b6098bf0c4fb98927a05f6d
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-thrombocytic-platelet|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

VEGFC PCSK6 PDE5A FHL2 SCGB1C1

3.55e-06172605d588ca825ab301910c1378e009b766c809b0bd5e
ToppCellInfluenza_Severe-Platelet|Influenza_Severe / Disease group and Cell class

SCGB1C2 PCSK6 PDE5A FHL2 SCGB1C1

4.55e-061816054d037b098bb6f780ed8b15c0ec23a6f4d86bf45a
ToppCellsevere_influenza-Platelet|severe_influenza / disease group, cell group and cell class (v2)

VEGFC PCSK6 PDE5A FHL2 SCGB1C1

4.68e-061826052018b71ec26bf3cd7ecdc04d5473900a697cd58a
ToppCellPBMC-Control-Hematopoietic|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SCGB1C2 PCSK6 PDE5A FHL2 SCGB1C1

5.06e-06185605c95c77d4302d7fff7fdef1774f15a93ba9ced61a
ToppCellPBMC-Control-Hematopoietic|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SCGB1C2 PCSK6 PDE5A FHL2 SCGB1C1

5.06e-0618560572a281ef246de5b30de1241d792c25bfae60e797
ToppCellControl-Hematopoietic_Mega-Platelet|Control / Disease group, lineage and cell class

SCGB1C2 PCSK6 PDE5A FHL2 SCGB1C1

5.33e-0618760553e9665e1feb02ce8fe78ff4128fd4beacef8471
ToppCellControl-Hematopoietic_Mega|Control / Disease group, lineage and cell class

SCGB1C2 PCSK6 PDE5A FHL2 SCGB1C1

5.33e-061876057bf98bdc83feb3918dbcf12e87a64fe4d2d41eba
ToppCellHealthy/Control-Platelet|World / Disease group and Cell class

VEGFC SCGB1C2 PCSK6 PDE5A FHL2

5.47e-06188605552077e4597d0956f4d8c40c9de8f109e87cb857
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT10 MALRD1 KCTD16 LTBP2 NOS1

5.47e-061886052ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellHealthy/Control-Platelet|Healthy/Control / Disease group and Cell class

VEGFC SCGB1C2 PCSK6 PDE5A FHL2

5.62e-061896053de7f8d8b8451ed9a146cce499552e9a060e9099
ToppCellHealthy-Platelet|Healthy / disease group, cell group and cell class

SCGB1C2 PCSK6 PDE5A FHL2 SCGB1C1

5.62e-061896055863e132536594e49bffbb637454cc43dfdbaa20
ToppCellHealthy-Platelet|World / disease group, cell group and cell class

SCGB1C2 PCSK6 PDE5A FHL2 SCGB1C1

5.62e-06189605c3d8e3682cb489bca887039cbea6c4cfc264de2f
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAM19 MYCBP2 KAT6A PDE5A LTBP2

5.76e-06190605d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

VEGFC FBLN5 KCTD16 PDE5A LTBP2

6.06e-0619260599ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellLA|World / Chamber and Cluster_Paper

GALNT10 FBLN5 ADAM19 PCSK6 LTBP2

6.22e-06193605d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

VEGFC SCUBE1 ADAM19 PCSK6 DYSF

6.22e-06193605479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

VEGFC QSOX1 FBLN5 MATN2 NOS1

6.38e-06194605582db7f7fa9aa08027ae18ed607945b5d1dc908a
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

VEGFC QSOX1 FBLN5 MATN2 NOS1

6.38e-06194605bda89111386398a072b70e8153b2a762298a047a
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

VEGFC FBLN5 KCTD16 PDE5A LTBP2

6.54e-0619560561c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell368C-Fibroblasts-Fibroblast-G|368C / Donor, Lineage, Cell class and subclass (all cells)

QSOX1 FBLN5 KCTD16 PDE5A LTBP2

6.87e-06197605156155c2f0c1a2461e45803da578af18ee221660
ToppCell368C-Fibroblasts-Fibroblast-G-|368C / Donor, Lineage, Cell class and subclass (all cells)

QSOX1 FBLN5 KCTD16 PDE5A LTBP2

6.87e-06197605d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

QSOX1 FBLN5 KCTD16 PDE5A LTBP2

7.04e-06198605e0e47cf65774191981840b22905b2094b95abe0f
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NELL2 SCUBE1 ADAM19 PDE5A DYSF

7.04e-0619860522e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell(5)_Fibroblast-G|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

QSOX1 FBLN5 KCTD16 PDE5A LTBP2

7.22e-06199605b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCellnormal_Lung-Endothelial_cells-Stalk-like_ECs|Endothelial_cells / Location, Cell class and cell subclass

VEGFC FBLN5 MYCBP2 MATN2 NOS1

7.39e-06200605413ac64bbe95b8c921c5396d8b5f298fec8c4f82
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VEGFC FBLN5 KCTD16 PDE5A LTBP2

7.39e-0620060534f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Serpinf1-Serpinf1_Clrn1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KCTD16 LTBP2 TEX15 VDR

1.96e-05118604702548d8187d54e8814375e5ae7609631fc71d5f
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Serpinf1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KCTD16 PDE5A TEX15 VDR

4.88e-051496045293c50b3fb41b1edaf9a97354899bd13770078c
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBLN5 SCUBE2 PDE5A FHL2

5.98e-05157604beab0ac47202266b04543c02cfcdda012375e879
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NELL2 TTC12 PDE5A HERC2

6.59e-051616045fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KCTD16 PDE5A LTBP2 FHL2

6.75e-051626043f264263878af630921911c2b344ac56eb1e7099
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN LTBP2 USH2A SPINK5

7.95e-0516960412bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FBLN5 MATN2 ZNF629 NOS1

8.32e-051716046a2f88c2a62cb2f69797804e24eb1137a3e148de
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FBLN5 MATN2 ZNF629 NOS1

8.32e-051716049be3554626408bb897d1f1c43b3ab4a92651f2e2
ToppCellcellseq-Immune-Hematopoietic-Megakaryocyte/Platelet-Megakaryocyte/Platelet|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SCGB1C2 PCSK6 PDE5A SCGB1C1

8.51e-05172604d0c3fb48c61762dcefca858cf13c9da8eb6d0f5e
ToppCellcellseq-Immune-Hematopoietic-Megakaryocyte/Platelet|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SCGB1C2 PCSK6 PDE5A SCGB1C1

8.51e-05172604eb2915165cab2660511e4b70c3a6d3ab2f770809
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT10 USP24 NOS1 VDR

8.70e-051736044bc6d93716f093b460c8b047199db8cab5fea720
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

NELL2 FBLN5 PLXDC1 MATN2

8.70e-05173604090dc3c5bd2652a65c2490fc889da858c3af368f
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN PLXDC1 ADAM21 ZNF629

8.90e-05174604268be5e7d2a18b866770b7cdb966c3958c7e6534
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN PLXDC1 ADAM21 ZNF629

8.90e-051746044cdf2eedc28d88d18241ee390092426fdf849e79
ToppCell10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega|lymph-node_spleen / Manually curated celltypes from each tissue

SCGB1C2 PDE5A FHL2 SCGB1C1

9.10e-051756045ca3369ce2c2bb88ba097260195aecd67cec1a3a
ToppCell(9)_Platelet|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

SCGB1C2 PDE5A FHL2 SCGB1C1

9.51e-051776040830944c43de300815831a9e2b2fce40965e7d12
ToppCell(9)_Platelet|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

SCGB1C2 PDE5A FHL2 SCGB1C1

9.51e-05177604e63d01c7fce4fa1256212fa7e95f74281edb3a01
ToppCell390C-Fibroblasts-Fibroblast-G|390C / Donor, Lineage, Cell class and subclass (all cells)

FBLN5 KCTD16 PDE5A LTBP2

1.01e-04180604137fc14859c89e1ecd98bee388bb58c04b835847
ToppCell390C-Fibroblasts-Fibroblast-G-|390C / Donor, Lineage, Cell class and subclass (all cells)

FBLN5 KCTD16 PDE5A LTBP2

1.01e-04180604cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCellInfluenza_Severe-Platelet|World / Disease group and Cell class

PCSK6 PDE5A FHL2 SCGB1C1

1.04e-041816045cdf935a89440114a58fa2042c1daed740d91c00
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT10 USP24 NOS1 VDR

1.04e-04181604e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCellMesenchymal_cells-Adipo-CAR|Mesenchymal_cells / Lineage and Cell class

VEGFC FBLN5 LTBP2 FHL2

1.04e-041816041cfb03eb03a37b036b4eeacec69c9b8163af1ee4
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SCGB1C2 PCSK6 PDE5A SCGB1C1

1.10e-04184604a5d904dd030d9c21be0f8b9ec432025f90fb5b8e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT10 MALRD1 LTBP2 NOS1

1.10e-04184604e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TRAF4 PLXDC1 PDE5A LTBP2

1.10e-0418460423c24ab5786af33d605bc445d06117b9da6c6331
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SCGB1C2 PCSK6 PDE5A SCGB1C1

1.10e-041846047617a00b2ebd6c5c9386c39a7e8220fdbf8669ff
ToppCell(7)_DC_activated|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ADCY10 NELL2 NOS1 LYPD8

1.10e-04184604b89871a3e36fde6daa68daf116f8c8d587554c0f
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBLN5 ADAM19 PLXDC1 ZNF217

1.13e-04185604e1fbec55b71f604189eb2431768fadbaa0453a83
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBLN5 ADAM19 PLXDC1 ZNF217

1.13e-041856049d933cd5ebc8368fd37aa83113d2dfa6938ff72d
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TRAF4 PLXDC1 PDE5A LTBP2

1.13e-04185604b1e84228c95be8ccf7c3c1afb66b71ffb93cf61e
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN5 PCSK6 GATA4 FHL2

1.15e-04186604a66da8453bb78f7e9f5f59452b3c50ae679d83c3
ToppCell(0)_MSCs|World / Cell class and subclass of bone marrow stroma cells in homeostatis

VEGFC FBLN5 LTBP2 FHL2

1.15e-04186604a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell(0)_MSCs-(00)_Lepr-MSC|World / Cell class and subclass of bone marrow stroma cells in homeostatis

VEGFC FBLN5 LTBP2 FHL2

1.15e-04186604f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCellsevere-Others|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

VEGFC PCSK6 PDE5A FHL2

1.15e-04186604234a4bc7c3529daf8804f2a366887d02a47075cd
ToppCellMesenchymal_cells-Adipo-CAR|World / Lineage and Cell class

VEGFC FBLN5 LTBP2 FHL2

1.15e-041866046ca8ce7ced91d6308b7c056032ffec1b37c974bf
ToppCellsevere-Others-Megakaryocytes|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

VEGFC PCSK6 PDE5A FHL2

1.17e-04187604ef16331d1e5abe6bde7f09793c4a87a6ac24e592
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

GALNT10 FBLN5 PCSK6 LTBP2

1.17e-041876044ea486991f66c29728d127171a07b81404ec0b78
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

VEGFC FBLN5 KCTD16 LTBP2

1.17e-0418760492d468dde81125d51daf7abd4703741abe1ab91c
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

VEGFC KCTD16 PDE5A LTBP2

1.17e-04187604e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellPBMC-Mild-Hematopoietic|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SCGB1C2 PCSK6 PDE5A FHL2

1.20e-04188604e3d9919eafc6181d2145b9d36f47066d0e22a8bd
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

FBLN5 PLXDC1 PCSK6 LTBP2

1.20e-04188604fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SCUBE1 ADAM19 LTBP2 FHL2

1.20e-04188604f54b063025d80de631382bf5326bc40aab7f7d00
ToppCellPBMC-Mild-Hematopoietic|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SCGB1C2 PCSK6 PDE5A FHL2

1.20e-041886046bd9317be8918da639254f4bdd432647c43ba9b1
ToppCellsevere_influenza-Platelet|World / disease group, cell group and cell class (v2)

PCSK6 PDE5A FHL2 SCGB1C1

1.20e-04188604b54632baa682aaf51100d44e7f114a54d5edd695
ToppCellP28-Mesenchymal-developing_mesenchymal_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TRAF4 PLXDC1 PDE5A LTBP2

1.20e-04188604e7681efb4d2de7f1d8a89552fff76a829376bf1b
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADAM19 MATN2 LTBP2 FHL2

1.20e-041886043004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCellPBMC-Severe-Hematopoietic-Platelet-Platelet-plt_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SCGB1C2 PCSK6 PDE5A SCGB1C1

1.22e-04189604d357fa946b9d6af46c15402f68758fb9c747bcaf
ToppCellPBMC-Severe-Hematopoietic-Platelet-Platelet-plt_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SCGB1C2 PCSK6 PDE5A SCGB1C1

1.22e-041896048b4a9434d7b7ca8cf74712227407ed7c96ce02f8
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADAM19 MATN2 LTBP2 FHL2

1.22e-04189604f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCellAT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

QSOX1 GALNT10 SCUBE2 RRM2B

1.22e-041896042d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN5 MATN2 PCSK6 GATA4

1.22e-041896042a5fda73d38bdc23cf47e5335ffd4e086e990245
ToppCellPBMC-Mild-Hematopoietic-Platelet|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SCGB1C2 PCSK6 PDE5A FHL2

1.25e-04190604726aeb280ea911f3551b18e388c4f7580ae2ea74
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet-plt_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SCGB1C2 PCSK6 PDE5A FHL2

1.25e-04190604b719061be370ffc293854f1f6e526bf33cd2f442
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SCGB1C2 PCSK6 PDE5A FHL2

1.25e-0419060450ea3ff7ba1ca335b4e4538fae5f9b74b1fc10f7
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet-plt_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SCGB1C2 PCSK6 PDE5A FHL2

1.25e-04190604427038bae9c7b3a9441c8d59ace69da74e9d37bf
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SCGB1C2 PCSK6 PDE5A FHL2

1.25e-04190604a1f8757dc719ed030f67d65735358a8d7a407bad
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SCUBE1 ADAM19 LTBP2 FHL2

1.25e-04190604938d1f66094b1c94606e0d40213a39e5112f3322
ToppCellPBMC-Mild-Hematopoietic-Platelet|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SCGB1C2 PCSK6 PDE5A FHL2

1.25e-04190604c4f55f5a0c42aeb571791925ea80e02fac320608
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Lymphocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZMAT5 MYCBP2 COA4 RBM48

1.25e-04190604373629dde5eda722424c5e6087763f0c5db67cf4
ToppCellP07|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBLN5 ADAM19 PDE5A LTBP2

1.25e-0419060438a613a9bca0ba040c3ada00286d1ce6f83ab23a
ToppCellCOVID-19_Mild-Hematopoietic_Mega-Platelet|COVID-19_Mild / Disease group, lineage and cell class

SCGB1C2 PCSK6 PDE5A FHL2

1.27e-041916046b3cfc670f69ed3e757cbf7498943e549e31326e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT10 MALRD1 LTBP2 NOS1

1.27e-04191604963f4f2e852bbb4faf070aafb0d368297abacd3b
DrugDihydrostreptomycin sulfate [5490-27-7]; Up 200; 2.8uM; MCF7; HT_HG-U133A

NELL2 ADAM19 PCSK6 KAT6A PDE5A LTBP2 USH2A

8.55e-071976072237_UP
Drugamyl nitrate

FBLN5 PDE5A

6.83e-062602CID000061250
Diseaseimpotence (implicated_via_orthology)

PDE5A NOS1

3.79e-0415572DOID:1875 (implicated_via_orthology)
DiseaseLeft Ventricle Remodeling

GATA4 NOS1

7.52e-0421572C0600520
DiseaseVentricular Remodeling

GATA4 NOS1

7.52e-0421572C0600519
Diseaseactivities of daily living score measurement

FHL2 NOS1

7.52e-0421572EFO_0008451
Diseasesunburn

HERC2 PRDM7 WDPCP

8.60e-0496573EFO_0003958
Diseasesuntan

HERC2 PRDM7 PRDM15

1.05e-03103573EFO_0004279
Diseasecorneal endothelial cell measurement

GATA4 FHL2 ZNF121

1.21e-03108573EFO_0010079
Diseaseanxiety measurement

GALNT10 NOS1 WDPCP

1.21e-03108573EFO_0009863

Protein segments in the cluster

PeptideGeneStartEntry
ATGFHFNAMTCEGCK

VDR

31

P11473
FGMTHDSADCCSASA

ADAM19

351

Q9H013
TLGMQHDEEFCFCGE

ADAM21

346

Q9UKJ8
HDEEFCFCGERGCIM

ADAM21

351

Q9UKJ8
MLNAFANEDFSCHGD

ANKRD18B

726

A2A2Z9
HALECAMDIFDFCSQ

ADCY10

361

Q96PN6
FMHGVCREGSQCLFS

MKRN2

11

Q9H000
EDFRQDFHSEMSGFC

RBM48

166

Q5RL73
FFGCRDCASHFEQMA

QSOX1

446

O00391
NADNMLFCDSCDRGF

KAT6B

281

Q8WYB5
RDENGFKCHCMSESH

KIN

36

O60870
SDHGCEYSCVNMDRS

MATN2

491

O00339
KGYDFCSERHNCMEN

NELL2

396

Q99435
AFDMLSECGFHMVAC

KCTD16

236

Q68DU8
QFEDTRESMHAFCVG

HERC2

1266

O95714
HGNTCSMCEVFFQAE

SPINK5

396

Q9NQ38
HGNTCSMCEAFFQQE

SPINK5

466

Q9NQ38
HGNTCSMCEAFFQQE

SPINK5

596

Q9NQ38
GSCMDCSESDHRIFM

GALNT10

561

Q86SR1
TNHTCSNADETFCEM

PCSK6

931

P29122
CSDSFSSVFHMECEE

PDE5A

376

O76074
MFARFGICEFLHCSE

PDE8A

521

O60658
LGDCSFLNTCFHMDT

METTL3

311

Q86U44
VFDARDCTTAHGMFN

NOS1

431

P29475
EMCQNFFIDSCAAHG

PRDM9

206

Q9NQV7
DNMLFCDSCDRGFHM

KAT6A

276

Q92794
ERCDFEDGLCHMTQD

MALRD1

71

Q5VYJ5
DRDSFCHQMSFCLTE

WDPCP

26

O95876
DMFDDFSEGRECVNC

GATA4

206

P43694
SLVFCCMRNAFHEND

CYP4A22

226

Q5TCH4
MTERFDCHHCNESLF

FHL2

1

Q14192
ECANDTMCGSHGFCD

LTBP2

1306

Q14767
TCDCFEGFQLDAAHM

LTBP2

1756

Q14767
NMFCSAENCSEETHI

LYPD8

66

Q6UX82
DGVHCSDMDECSFSE

FBLN5

241

Q9UBX5
SDMDECSFSEFLCQH

FBLN5

246

Q9UBX5
HFSSFGDVACMAICS

SEC22C

61

Q9BRL7
TCFDGFMLAHDGHNC

SCUBE1

101

Q8IWY4
CTCFDGFMLAHDGHN

SCUBE2

111

Q9NQ36
HDTYGADEFMGRCIC

DYSF

1231

O75923
FMFCQAIGFSCSSAH

TAS2R45

261

P59539
SMEATEHCGRCDFNF

USH2A

3406

O75445
FHNCRTDDKTFQCEM

PRDM15

816

P57071
EMCQNFFIDSCAAHG

PRDM7

206

Q9NQW5
CICRMATGEDNDEFF

SCGB1C2

16

P0DMR2
FCNACHDDFQRMTSI

MYCBP2

4616

O75592
RSGCAASHFAVQECM

COA4

31

Q9NYJ1
RDEGLHCDFACLMFQ

RRM2B

226

Q7LG56
GFVHSMCQTAQSFCD

VPS51

496

Q9UID3
SNERPFACHMCDKAF

ZBTB14

356

O43829
NHICRCLAQEDFMFS

VEGFC

251

P49767
MCEECGKAFNSSHEL

ZNF607

646

Q96SK3
CICRMATGEDNDEFF

SCGB1C1

16

Q8TD33
CDFSGEAYESHEGMC

TRAF4

146

Q9BUZ4
RPFAGVTACMDFCAH

TET3

1061

O43151
CDFMENGEIFSEHSC

ZNF121

11

P58317
SDMDKASFVQCCLFH

ZNF416

151

Q9BWM5
RNDTNFHGVCMFCNE

ZNF277

166

Q9NRM2
DDMARSCAKSFCENF

USP24

1191

Q9UPU5
CDFGSNCRFSHMSER

ZMAT5

66

Q9UDW3
RHMAACEEFGDGCLS

TTC12

466

Q9H892
DCMFCSQTFTHSEDL

ZNF217

66

O75362
QHRSCDACMSSDLTF

PLXDC1

306

Q8IUK5
IMEHCSDCFDFSLSV

TEX15

1796

Q9BXT5
RTHMDENLFVCSDCG

ZNF629

506

Q9UEG4
DTCHSGFSGMFCSDR

ZAN

1441

Q9Y493