Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	B12D	NDUFA4L2 NDUFA4	4.63e-05	3	74	2	IPR010530
Domain	B12D	NDUFA4L2 NDUFA4	4.63e-05	3	74	2	PF06522
Domain	VWC	NELL1 VWF PXDN	1.82e-04	28	74	3	PF00093
Domain	VWFC_1	NELL1 VWF PXDN	3.88e-04	36	74	3	PS01208
Domain	TyrKc	JAK2 ROR2 EPHA1 PTK7	4.12e-04	88	74	4	SM00219
Domain	Tyr_kinase_cat_dom	JAK2 ROR2 EPHA1 PTK7	4.12e-04	88	74	4	IPR020635
Domain	VWC	NELL1 VWF PXDN	4.56e-04	38	74	3	SM00214
Domain	VWFC_2	NELL1 VWF PXDN	4.56e-04	38	74	3	PS50184
Domain	PROTEIN_KINASE_TYR	JAK2 ROR2 EPHA1 PTK7	5.96e-04	97	74	4	PS00109
Domain	Tyr_kinase_AS	JAK2 ROR2 EPHA1 PTK7	5.96e-04	97	74	4	IPR008266
Domain	VWF_dom	NELL1 VWF PXDN	6.13e-04	42	74	3	IPR001007
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH9	1.37e-03	14	74	2	IPR024317
Domain	Dynein_HC_stalk	DNAH3 DNAH9	1.37e-03	14	74	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH3 DNAH9	1.37e-03	14	74	2	IPR013602
Domain	DHC_N2	DNAH3 DNAH9	1.37e-03	14	74	2	PF08393
Domain	MT	DNAH3 DNAH9	1.37e-03	14	74	2	PF12777
Domain	AAA_8	DNAH3 DNAH9	1.37e-03	14	74	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH3 DNAH9	1.37e-03	14	74	2	IPR011704
Domain	AAA_5	DNAH3 DNAH9	1.37e-03	14	74	2	PF07728
Domain	DHC_fam	DNAH3 DNAH9	1.57e-03	15	74	2	IPR026983
Domain	Dynein_heavy_dom	DNAH3 DNAH9	1.57e-03	15	74	2	IPR004273
Domain	Dynein_heavy	DNAH3 DNAH9	1.57e-03	15	74	2	PF03028
Domain	Pkinase_Tyr	JAK2 ROR2 EPHA1 PTK7	1.72e-03	129	74	4	PF07714
Domain	Ser-Thr/Tyr_kinase_cat_dom	JAK2 ROR2 EPHA1 PTK7	2.20e-03	138	74	4	IPR001245
Domain	Rib_L2_dom2	SUPT5H TP53BP1	2.27e-03	18	74	2	IPR014722
Domain	-	SUPT5H TP53BP1	2.27e-03	18	74	2	2.30.30.30
Domain	IGc2	PXDN HMCN1 ROR2 LILRA5 PTK7	2.41e-03	235	74	5	SM00408
Domain	Ig_sub2	PXDN HMCN1 ROR2 LILRA5 PTK7	2.41e-03	235	74	5	IPR003598
Domain	VWC_out	NELL1 VWF	2.54e-03	19	74	2	SM00215
Domain	BRCT	PARP4 TP53BP1	2.54e-03	19	74	2	PF00533
Domain	-	PARP4 VWF HMCN1	3.16e-03	74	74	3	3.40.50.410
Domain	Prot_kinase_dom	JAK2 TGFBR1 ROR2 BUB1B LRRK1 EPHA1 PTK7	3.21e-03	489	74	7	IPR000719
Domain	PROTEIN_KINASE_DOM	JAK2 TGFBR1 ROR2 BUB1B LRRK1 EPHA1 PTK7	3.35e-03	493	74	7	PS50011
Domain	BRCT	PARP4 TP53BP1	3.40e-03	22	74	2	SM00292
Domain	-	PARP4 TP53BP1	3.71e-03	23	74	2	3.40.50.10190
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NELL1 TRAF2 CS ITCH VWF DNAJC14 SUPT5H GNPTAB RANBP9 RAD54L2 CABIN1 SEC31B PBXIP1 DHX30	9.25e-07	1285	78	14	35914814
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	FLNC TRAF2 MIA3 ITCH VWF PRRC2C PBXIP1 TP53BP1	1.52e-06	360	78	8	33111431
Pubmed	Impaired flow mediated dilatation as evidence of endothelial dysfunction in chronic atrial fibrillation: relationship to plasma von Willebrand factor and soluble E-selectin levels.	SELE VWF	4.97e-06	2	78	2	17996280
Pubmed	Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria.	JAK2 MCTS1	4.97e-06	2	78	2	37875108
Pubmed	Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow.	UGT8 DBH	4.97e-06	2	78	2	16439213
Pubmed	Endothelial activation markers soluble E-selectin and von Willebrand factor in primary hyperparathyroidism.	SELE VWF	4.97e-06	2	78	2	21471547
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	FLNC SAAL1 CS ANKFY1 ITCH RANBP9 MSH2 PSMD12 TP53BP1 CA2 PPP6R3	1.48e-05	1005	78	11	19615732
Pubmed	Endothelial markers are associated with pancreatic necrosis and overall prognosis in acute pancreatitis: A preliminary cohort study.	SELE VWF	1.49e-05	3	78	2	28007459
Pubmed	Epithelial IL5RA promotes epithelial-mesenchymal transition in pulmonary fibrosis via Jak2/STAT3 cascade.	JAK2 IL5RA	1.49e-05	3	78	2	38191068
Pubmed	Endothelial cell markers in patients with pseudoexfoliation syndrome.	SELE VWF	1.49e-05	3	78	2	22593709
Pubmed	Identification of a Z-band associated protein complex involving KY, FLNC and IGFN1.	KY FLNC	1.49e-05	3	78	2	20206623
Pubmed	RanBPM interacts with TβRI, TRAF6 and curbs TGF induced nuclear accumulation of TβRI.	TGFBR1 RANBP9	1.49e-05	3	78	2	24103590
Pubmed	Analysis of Hemicentin-1, hOgg1, and E-selectin single nucleotide polymorphisms in age-related macular degeneration.	SELE HMCN1	2.97e-05	4	78	2	17057786
Pubmed	Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.	DNAH3 DNAH9	2.97e-05	4	78	2	11175280
Pubmed	Expression of TLR7, TLR9, JAK2, and STAT3 genes in peripheral blood mononuclear cells from patients with systemic sclerosis.	JAK2 TLR7	2.97e-05	4	78	2	29147913
Pubmed	Murine NFX.1: isolation and characterization of its messenger RNA, mapping of its chromosomal location and assessment of its developmental expression.	TGFBR1 NFX1	2.97e-05	4	78	2	12047746
Pubmed	AIP4 restricts transforming growth factor-beta signaling through a ubiquitination-independent mechanism.	TGFBR1 ITCH	2.97e-05	4	78	2	15946939
Pubmed	JAK2 and JAK1 constitutively associate with an interleukin-5 (IL-5) receptor alpha and betac subunit, respectively, and are activated upon IL-5 stimulation.	JAK2 IL5RA	2.97e-05	4	78	2	9516124
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	FLNC SUPT5H PRRC2C RANBP9 NDUFA4 TP53BP1 CA2	3.26e-05	399	78	7	35987950
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	PIGT SAAL1 CS SUPT5H PRRC2C MCTS1 RANBP9 MSH2 PSMD12 NDUFA4 DHX30 PPP6R3	4.07e-05	1335	78	12	29229926
Pubmed	Filamin C interacts with the muscular dystrophy KY protein and is abnormally distributed in mouse KY deficient muscle fibres.	KY FLNC	4.94e-05	5	78	2	15385448
Pubmed	The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation.	TRAF2 ITCH	4.94e-05	5	78	2	22057290
Pubmed	Defining the membrane proteome of NK cells.	PARP4 PIGT MIA3 ITCH DNAJC14 PRRC2C LSS MSH2 PSMD12 CTSA CCDC88B	5.80e-05	1168	78	11	19946888
Pubmed	PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential.	TGFBR1 ROR2 ARC PTK7	6.12e-05	94	78	4	32062451
Pubmed	Increased serum vWF and sVCAM-1 levels are associated with late or very late angiographic stent thrombosis after sirolimus-eluting stent implantation.	SELE VWF	7.40e-05	6	78	2	20508517
Pubmed	Itch E3 ligase-mediated regulation of TGF-beta signaling by modulating smad2 phosphorylation.	TGFBR1 ITCH	7.40e-05	6	78	2	15350225
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	TGFBR1 PIGT MIA3 PXDN GNPTAB ROR2 UGT8 CTSA PBXIP1 PTK7 PPP6R3	7.44e-05	1201	78	11	35696571
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	FLNC PIGT MIA3 UGT8 LSS PBXIP1 TP53BP1 PEX26 CA2 PTK7 PPP6R3	7.55e-05	1203	78	11	29180619
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	FLNC ITCH RANBP9 PBXIP1 DHX30 PPP6R3	7.55e-05	313	78	6	38270169
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	PIGT SAAL1 PXDN PRRC2C BUB1B RANBP9 MSH2 PSMD12 CABIN1 CTSA PBXIP1 PPP6R3	8.39e-05	1440	78	12	30833792
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	PRUNE2 FLNC CS ANKFY1 SUPT5H MCTS1 BUB1B RANBP9 MSH2 PSMD12 CTSA PPP6R3	9.26e-05	1455	78	12	22863883
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	PARP4 PXDN PRRC2C MSH2 DHX30	9.41e-05	202	78	5	33005030
Pubmed	Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.	ROR2 EPHA1 PTK7	1.01e-04	40	78	3	30898150
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PARP4 MIA3 SUPT5H PRRC2C BUB1B RAD54L2 PBXIP1 PTK7	1.06e-04	650	78	8	38777146
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FLNC SUPT5H PRRC2C MSH2 PSMD12 TP53BP1 DHX30 PPP6R3	1.09e-04	653	78	8	22586326
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MIA3 ITCH DNAJC14 ROR2 BUB1B LSS NDUFA4 PBXIP1 TP53BP1 PTK7 DHX30 PPP6R3	1.14e-04	1487	78	12	33957083
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	FLNC PARP4 TROAP PSMD12 LRRK1 TP53BP1 PPP6R3	1.24e-04	494	78	7	26831064
Pubmed	Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes.	TRAF2 ITCH	1.38e-04	8	78	2	20185725
Pubmed	TGF-β Targets the Hippo Pathway Scaffold RASSF1A to Facilitate YAP/SMAD2 Nuclear Translocation.	TGFBR1 ITCH	1.38e-04	8	78	2	27292796
Pubmed	K63-linked ubiquitination of DYRK1A by TRAF2 alleviates Sprouty 2-mediated degradation of EGFR.	TRAF2 RAD54L2	1.38e-04	8	78	2	34117217
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	TRAF2 PIGT MIA3 ITCH PXDN PRRC2C PSMD12 CTSA TP53BP1 DHX30 PPP6R3	1.46e-04	1297	78	11	33545068
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	NELL1 TRAF2 MIA3 VWF	1.48e-04	118	78	4	21078624
Pubmed	DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169.	FLNC TRAF2 TROAP RAD54L2	1.68e-04	122	78	4	30773093
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	PIGT SAAL1 CS SUPT5H RANBP9 MSH2 PSMD12 CTSA PCDH9 TP53BP1 DHX30	1.72e-04	1321	78	11	27173435
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	TGFBR1 SAAL1 CS RANBP9 MSH2 CTSA PTK7	1.97e-04	533	78	7	25544563
Pubmed	Identification of a 14-3-3 binding sequence in the common beta chain of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors that is serine-phosphorylated by GM-CSF.	JAK2 IL5RA	2.21e-04	10	78	2	10477722
Pubmed	The contribution of genetic factors to thrombotic and bleeding outcomes in coronary patients randomised to IIb/IIIa antagonists.	SELE VWF	2.21e-04	10	78	2	12082590
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	FLNC CS ANKFY1 PRRC2C RANBP9 CA2 DHX30	2.41e-04	551	78	7	34728620
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	MIA3 SAAL1 ITCH PXDN UGT8 LSS MSH2 PTK7 PPP6R3	2.59e-04	942	78	9	31073040
Pubmed	Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array.	PARP4 MSH2 TP53BP1	2.62e-04	55	78	3	19536092
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	NELL1 CASC3 TRAF2 VWF NDUFA4L2 RAD54L2 CCDC88B	2.66e-04	560	78	7	21653829
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	SUPT5H PRRC2C RANBP9 PSMD12 DHX30	2.68e-04	253	78	5	29911972
Pubmed	USP11 augments TGFβ signalling by deubiquitylating ALK5.	TGFBR1 ITCH	2.70e-04	11	78	2	22773947
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CASC3 MIA3 ANKFY1 ITCH PRRC2C RANBP9 ARC CABIN1 TP53BP1	3.04e-04	963	78	9	28671696
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	FLNC DUSP21 SUPT5H RANBP9 MSH2 PSMD12 NDUFA4 PTK7 PPP6R3	3.30e-04	974	78	9	28675297
Pubmed	The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.	FLNC HMCN1 SUPT5H PRRC2C	3.43e-04	147	78	4	28977470
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	DUSP21 SUPT5H ROR2 LRRK1 EPHA1 PTK7	3.69e-04	420	78	6	28065597
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	PRRC2C MSH2 TP53BP1 PPP6R3	3.99e-04	153	78	4	26365490
Pubmed	Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.	ANKFY1 RANBP9 DHX30 PPP6R3	4.29e-04	156	78	4	22952844
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	PXDN HMCN1 ROR2 PTK7	4.95e-04	162	78	4	25826454
Pubmed	The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1.	TRAF2 ITCH	5.12e-04	15	78	2	21765415
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	PIGT PXDN UGT8 CTSA	5.18e-04	164	78	4	32409323
Pubmed	The human plasma proteome: a nonredundant list developed by combination of four separate sources.	VWF DBH CTSA CA2	5.30e-04	165	78	4	14718574
Pubmed	A protein interaction landscape of breast cancer.	SUPT5H LSS MSH2 CTSA PBXIP1 DHX30 PPP6R3	5.59e-04	634	78	7	34591612
Pubmed	Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis.	SELE DBH	5.84e-04	16	78	2	10391210
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	SAAL1 ITCH PXDN PRRC2C PSMD12 TP53BP1 PPP6R3	6.29e-04	647	78	7	26618866
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	BUB1B RANBP9 MSH2 PSMD12 TP53BP1 PPP6R3	6.82e-04	472	78	6	38943005
Pubmed	Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells.	SUPT5H RANBP9 CABIN1 TP53BP1	7.04e-04	178	78	4	27637333
Pubmed	Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.	BUB1B MSH2 IL5RA TP53BP1	7.19e-04	179	78	4	19074885
Pubmed	A massively parallel pipeline to clone DNA variants and examine molecular phenotypes of human disease mutations.	TRAF2 SUPT5H BUB1B	7.59e-04	79	78	3	25502805
Pubmed	PELI1 Selectively Targets Kinase-Active RIP3 for Ubiquitylation-Dependent Proteasomal Degradation.	TRAF2 BUB1B	8.28e-04	19	78	2	29883609
Pubmed	Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.	MIA3 PXDN ARC	8.76e-04	83	78	3	9039502
Pubmed	The protein tyrosine kinase family of the human genome.	JAK2 ROR2 EPHA1	8.76e-04	83	78	3	11114734
Pubmed	Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.	ITCH MSH2 TP53BP1	9.39e-04	85	78	3	16051665
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	CS ANKFY1 MCTS1 RANBP9 PSMD12 NDUFA4 CA2 PPP6R3	1.04e-03	916	78	8	32203420
Pubmed	Myosin-X recruits lamellipodin to filopodia tips.	TRAF2 PSMD12 PPP6R3	1.07e-03	89	78	3	36861887
Pubmed	Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes.	CS LIPE	1.11e-03	22	78	2	15242332
Pubmed	USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling.	TGFBR1 ITCH	1.11e-03	22	78	2	24850914
Pubmed	The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.	CASC3 TROAP PRRC2C DHX30	1.15e-03	203	78	4	35012549
Pubmed	Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.	JAK2 TGFBR1 TLR7 IL5RA	1.17e-03	204	78	4	20503287
Pubmed	Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.	JAK2 TGFBR1 TLR7 IL5RA	1.19e-03	205	78	4	19258923
Pubmed	TIM-1 Ubiquitination Mediates Dengue Virus Entry.	TGFBR1 ITCH	1.22e-03	23	78	2	29742433
Pubmed	Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity.	TRAF2 TROAP	1.22e-03	23	78	2	22792062
Pubmed	Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.	JAK2 TGFBR1 TLR7 IL5RA	1.23e-03	207	78	4	17703412
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	ANKFY1 PRRC2C MSH2 PSMD12 CA2 DHX30	1.29e-03	534	78	6	35032548
Pubmed	USP10 regulates B cell response to SARS-CoV-2 or HIV-1 nanoparticle vaccines through deubiquitinating AID.	SUPT5H MSH2	1.33e-03	24	78	2	34983926
Pubmed	Two-hybrid analysis identifies PSMD11, a non-ATPase subunit of the proteasome, as a novel interaction partner of AMP-activated protein kinase.	FLNC PBXIP1	1.33e-03	24	78	2	19616115
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	PARP4 TROAP PRRC2C BUB1B PSMD12 NDUFA4 DHX30 PPP6R3	1.50e-03	971	78	8	33306668
Pubmed	Characterization of carbonic anhydrase IX interactome reveals proteins assisting its nuclear localization in hypoxic cells.	SAAL1 CA2	1.56e-03	26	78	2	23181366
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	MIA3 PRRC2C ROR2 PBXIP1 DHX30	1.57e-03	375	78	5	32788342
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	SUPT5H MSH2 RAD54L2 DHX30	1.59e-03	222	78	4	37071664
Pubmed	Proteomic and Interactome Approaches Reveal PAK4, PHB-2, and 14-3-3η as Targets of Overactivated Cdc42 in Cellular Responses to Genomic Instability.	FLNC PXDN MSH2 PSMD12	1.67e-03	225	78	4	31478661
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	PRUNE2 CABIN1 DNAH9	1.68e-03	104	78	3	9205841
Pubmed	Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo.	BUB1B TP53BP1	1.68e-03	27	78	2	24706806
Pubmed	Genetic polymorphisms, their allele combinations and IFN-beta treatment response in Irish multiple sclerosis patients.	JAK2 DBH	1.68e-03	27	78	2	19604093
Pubmed	Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment.	ROR2 PTK7	1.68e-03	27	78	2	30516471
Pubmed	Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics.	PRRC2C NFX1 RANBP9 PSMD12 DHX30	1.74e-03	384	78	5	31059266
Pubmed	Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.	MSH2 RAD54L2 TP53BP1	1.77e-03	106	78	3	19394292
Pubmed	Integrative predictive model of coronary artery calcification in atherosclerosis.	SELE VWF HMCN1 TLR7	1.78e-03	229	78	4	19948975
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TATDN3 JAK2 PRUNE2 CASC3 MIA3 ITCH PXDN ROR2 LSS PTK7	1.79e-03	1489	78	10	28611215
Cytoband	9q22	TGFBR1 ROR2	4.78e-04	19	78	2	9q22
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	PXDN HMCN1 ROR2 PTK7	8.69e-04	161	48	4	593
GeneFamily	Dyneins, axonemal	DNAH3 DNAH9	9.15e-04	17	48	2	536
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRUNE2 TGFBR1 GBP7 AOAH TLR7 CTSA LILRA5	2.77e-08	180	77	7	a600bc705993d3a010550a25d3b54358946f061f
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRUNE2 TGFBR1 GBP7 AOAH TLR7 CTSA	5.99e-07	175	77	6	53e6f1f8dd482dfa2539e068dacefbb6e08443bc
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRUNE2 GBP7 AOAH CTSA LILRA5	7.13e-06	154	77	5	79ebda35dd1719e157738d7c13e5b8ccc3991f03
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRUNE2 TGFBR1 GNPTAB AOAH LILRA5	8.85e-06	161	77	5	8937f6b92cb2a93ea8c4780d9200a518c3112e53
ToppCell	facs-MAT-Fat-3m-Myeloid-myeloid_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 AOAH TLR7 RAB44 LILRA5	9.39e-06	163	77	5	5fc836444bc156c8248abee001b0ecbe43f980c9
ToppCell	facs-Lung-24m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 TGFBR1 AOAH CTSA LILRA5	1.03e-05	166	77	5	7be2b5c62e2be3437ea50b9a473cf9fc7f05e0b1
ToppCell	facs-Lung-24m-Hematologic-myeloid-interstitial_macrophage\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 TGFBR1 AOAH CTSA LILRA5	1.03e-05	166	77	5	8418b191e7f16cb39301df3ddbfb1bab6c0632d6
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRUNE2 GBP7 AOAH CTSA LILRA5	1.22e-05	172	77	5	c96bd3407911df3e3e6d7a3dba786b11814b9598
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRUNE2 TGFBR1 AOAH TLR7 CTSA	1.22e-05	172	77	5	f0e767a20d93e546ce278db67dbd779cc68af533
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRUNE2 GBP7 AOAH TLR7 CTSA	1.29e-05	174	77	5	0a8fa44604be19fbac722ebc6d1cd72b71be7022
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRUNE2 TGFBR1 AOAH TLR7 CTSA	1.29e-05	174	77	5	f520b79d277e286c9bb5d091e6c94e7ec7e46699
ToppCell	356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TGFBR1 ROR2 TLR7 NDUFA4 CTSA	1.97e-05	190	77	5	d541e076137cf7334bdb0ed69db2f9a27c668c65
ToppCell	droplet-Heart-HEART-1m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC VWF HMCN1 SCN1A PTK7	2.12e-05	193	77	5	d0a5f212f8e8a13dbbe3e41df92548ef82eef70b
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE VWF TROAP BUB1B ARC	2.34e-05	197	77	5	76b61e60a757e58b465569538e632d6d9953e89a
ToppCell	3'-GW_trimst-1-SmallIntestine\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	UGT8 NDUFA4 CTSA NR0B2 CA2	2.46e-05	199	77	5	c4a1e0cf3be867e7cebbd8bd3668bc2df391671b
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SELE VWF PXDN HMCN1 CA2	2.46e-05	199	77	5	0602e2b2aa56d106da63bd342a38bef437b4d496
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-OPC_related-OPC\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	TROAP SCN1A BUB1B ARC UGT8	2.52e-05	200	77	5	02594c1edbc9f2cf831639cd83363abd2551cb94
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-OPC_related\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	TROAP SCN1A BUB1B ARC UGT8	2.52e-05	200	77	5	46521d83b917b0357601db8783c8da6b73730d60
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	PRUNE2 DNAJC14 ARC UGT8 ENPEP	2.52e-05	200	77	5	6b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCell	LPS_only-Hematopoietic_Myeloid-Granulocytic_cells-Mast-cells\|LPS_only / Treatment groups by lineage, cell group, cell type	DUSP21 GNPTAB DNAH9 RAB44 IL5RA	2.52e-05	200	77	5	afbbfe0b8e66df36c244935182cb26feeb31a085
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PXDN ROR2 NDUFA4 PCDH9 PTK7	2.52e-05	200	77	5	ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCell	Substantia_nigra-Hematopoietic-MACROPHAGE-MP1(C1qb)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	AOAH TLR7 RAB44 LILRA5	4.91e-05	116	77	4	e93dd059d272e597a30e93f4c0504636f4e6c899
ToppCell	Substantia_nigra-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	AOAH TLR7 RAB44 LILRA5	4.91e-05	116	77	4	27201cb805fe73b5ec51d7d585d047a4c043e8b0
ToppCell	Substantia_nigra-Hematopoietic-MACROPHAGE\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	AOAH TLR7 RAB44 LILRA5	4.91e-05	116	77	4	d3194bda2e3d5fd021e4015eed98c5888befe03d
ToppCell	Substantia_nigra-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	AOAH TLR7 RAB44 LILRA5	4.91e-05	116	77	4	4e84b6f6661bb5ba0fe0de38a23bee9cc3727d94
ToppCell	Substantia_nigra-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	AOAH TLR7 RAB44 LILRA5	4.91e-05	116	77	4	15d9a3d8c3cc1f6a1aead03cf84dc876c76b7063
ToppCell	LPS_only-Hematopoietic_Mast-Mast_cells-Mast-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DUSP21 GNPTAB RAB44 IL5RA	9.11e-05	136	77	4	82d7f90ef2a63a3137c331efd68c036cd0db3ac1
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NELL1 TROAP BUB1B NDUFA4	1.40e-04	152	77	4	f748ee34167f79ecda116aa1914afab47403385a
ToppCell	facs-Lung-EPCAM-24m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 TGFBR1 AOAH LILRA5	1.87e-04	164	77	4	4e0133a7f80cf6bd3d70f72ee26360df5f80ab32
ToppCell	Mild-MAIT\|World / Disease group and Cell class	PRUNE2 NYNRIN PBXIP1 CA2	1.87e-04	164	77	4	21dc02997dfae73cf70ce291661928526605dba1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PARP4 GNPTAB RAB44 IL5RA	1.87e-04	164	77	4	2c48c6e4eeee845f0563982d0bfa2a176ca5ef61
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 TGFBR1 AOAH LILRA5	1.87e-04	164	77	4	4ab1a7d5379a633c3f61af1c8c2df93b6961d9cf
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	PXDN NYNRIN RAB44 PTK7	1.92e-04	165	77	4	7b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRUNE2 AOAH CTSA MGME1	1.96e-04	166	77	4	bb8135119dc37fdbba476599a56d368f422688dc
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KY CCDC88B RAB44 IL5RA	2.01e-04	167	77	4	a813b95c2fafb638b249bc4fa4f708c6f39ad444
ToppCell	PND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TROAP DCP2 BUB1B CCDC88B	2.05e-04	168	77	4	4c402a1613fcf0a6e4d9b9d5551812940e91ff32
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 AOAH TLR7 LILRA5	2.05e-04	168	77	4	4ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 AOAH TLR7 LILRA5	2.05e-04	168	77	4	04e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AOAH TLR7 CCDC88B LILRA5	2.10e-04	169	77	4	c3d410a5e98000ba872141b62e17ef4ed3d1a8eb
ToppCell	facs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l12\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 TLR7 CTSA LILRA5	2.10e-04	169	77	4	8180aeda13c511260d0542a94156059d558848a7
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 AOAH TLR7 LILRA5	2.10e-04	169	77	4	454b92b9b67299a64278c010db033ca5b9d217a0
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Trf.Ctps_(Ctps)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	RAB44 IL5RA EPHA1	2.13e-04	67	77	3	820120f1f8500c948ef54280e5237f9b311f1b3e
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	RAB44 IL5RA EPHA1	2.13e-04	67	77	3	c6a3ac0829f924e0c7822df2ef8f45e7925f2d3d
ToppCell	390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TGFBR1 CCDC88B RAB44 CA2	2.15e-04	170	77	4	a6fa0cab1fa829ec601fe48306b4c43c83425b04
ToppCell	390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TGFBR1 CCDC88B RAB44 CA2	2.15e-04	170	77	4	b40255eee45eb18b5a297336d7f3845fd8f8aa3b
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFBR1 TLR7 DNAH9 LILRA5	2.15e-04	170	77	4	8e774af244cfe787fa0ea2b6be0c3c2d00bfe4fc
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFBR1 TLR7 DNAH9 LILRA5	2.15e-04	170	77	4	f5140eb9313c0d1bb31f8a761d9c062c56733a61
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GBP7 AOAH TLR7 CTSA	2.25e-04	172	77	4	714172f31abd0d25261df6115ec6a9df491fa14b
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	PRUNE2 TROAP BUB1B LILRA5	2.30e-04	173	77	4	783b8fa08b9d8f597f251793eae164151662f1f9
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	NDUFA4L2 ENPEP EPHA1	2.33e-04	69	77	3	a157b1582401cebd222343d94086dbea876140c2
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	NDUFA4L2 ENPEP EPHA1	2.33e-04	69	77	3	cdd42abdd072aa438830d837ee857529269a81e0
ToppCell	facs-Heart-LA-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 AOAH TLR7 LILRA5	2.35e-04	174	77	4	30c083fe4711735e83dccfd00fcd746ae673d353
ToppCell	facs-Heart-LV-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 AOAH TLR7 LILRA5	2.35e-04	174	77	4	54166a0faf748cccb6406c2c268e1e6e21caf6d0
ToppCell	facs-Heart-LA-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 AOAH TLR7 LILRA5	2.35e-04	174	77	4	46d19c1144fff19be682b7ba59d4c3e014f79e15
ToppCell	facs-Heart-LA-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 AOAH TLR7 LILRA5	2.35e-04	174	77	4	1802a52552256d1e25d8b328ba62dcfe41671900
ToppCell	facs-Heart-LV-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 AOAH TLR7 LILRA5	2.35e-04	174	77	4	dc8a238ec1d954bec0f8eb67c04a61734c96f5b5
ToppCell	facs-Heart-LV-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 AOAH TLR7 LILRA5	2.40e-04	175	77	4	5d106ef542b97f97aeb19179e3f72963ead1e82a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AOAH TLR7 LRRK1 LILRA5	2.45e-04	176	77	4	926ed37e636fe4dd3a18731cea15761f0c2c285a
ToppCell	COVID-19-Myeloid-MoAM4\|COVID-19 / Condition, Lineage and Cell class	NYNRIN RAB44 CA2 CAPN11	2.50e-04	177	77	4	ca5d0c3d5c700bbe4c2da068eb02be6229afb9a0
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TROAP BUB1B NDUFA4L2 GPRC6A	2.50e-04	177	77	4	2b63f0529ef73e0eede9b7ef1f08b0a0426a9c82
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRUNE2 AOAH CTSA LILRA5	2.50e-04	177	77	4	ab92ffc9624850a50c88e6b8f3a517ff2251ff15
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELE NDUFA4L2 ENPEP PTK7	2.50e-04	177	77	4	7c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELE NDUFA4L2 ENPEP PTK7	2.50e-04	177	77	4	e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NELL1 HMCN1 UGT8 PCDH9	2.56e-04	178	77	4	4df6218b20c2f076c22346d23260964cc0d73e65
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-Mast_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GNPTAB RAB44 IL5RA TP53BP1	2.56e-04	178	77	4	c6704fcd21a9d2fe45679a1d998f04213b3bf224
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 TGFBR1 RAB44 LILRA5	2.78e-04	182	77	4	3dec003bad0f3716cf8163861a9d4302a7d6df8c
ToppCell	droplet-Lung-nan-3m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 TGFBR1 RAB44 LILRA5	2.84e-04	183	77	4	ec3c05b9ce1e0fbb720e0dea41f1e28fd3fd878f
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 TROAP BUB1B LILRA5	2.84e-04	183	77	4	e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|normal_Lung / Location, Cell class and cell subclass	FLNC HMCN1 ROR2 PTK7	2.90e-04	184	77	4	0b336489c10e8c3c957795dd845454f03404382b
ToppCell	droplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 TGFBR1 RAB44 LILRA5	2.90e-04	184	77	4	15ea746c77785120f69f9ab370fb7eb9b70692f8
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NELL1 HMCN1 UGT8 PCDH9	2.90e-04	184	77	4	e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TGFBR1 BUB1B CTSA LILRA5	2.90e-04	184	77	4	8e5fc2bdd3071e782aa8c56b8a39f8ea8f03f623
ToppCell	droplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 TGFBR1 RAB44 LILRA5	2.90e-04	184	77	4	bd5e8fc453a6393b8778734a2c3c2f1281769bcd
ToppCell	droplet-Lung-nan-3m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 TGFBR1 RAB44 LILRA5	2.90e-04	184	77	4	3261d767d5e3d9e9fbac22ad73ca14e44beed89c
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 TGFBR1 RAB44 LILRA5	2.96e-04	185	77	4	afbb88325e4a81c15ac1d0a004e3e1f4ba2ee87b
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 TGFBR1 RAB44 LILRA5	2.96e-04	185	77	4	775b72319ef6acffd2c9a74293b9c1bccea33f42
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 SCN1A ROR2 DBH	2.96e-04	185	77	4	785c55d39909fac74415f24427979691e7e694e6
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 SCN1A ROR2 DBH	2.96e-04	185	77	4	97a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KY ENPEP EPHA1 PTK7	3.02e-04	186	77	4	ca5e9c6531cb5d199e27509bfab1d62e3937177e
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KY ENPEP EPHA1 PTK7	3.02e-04	186	77	4	1ed71b229f40a680071b14f5a7a19706e0fd14b1
ToppCell	droplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 TGFBR1 RAB44 LILRA5	3.02e-04	186	77	4	f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 FLNC VWF ARC	3.02e-04	186	77	4	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	droplet-Lung-nan-21m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 TGFBR1 RAB44 LILRA5	3.02e-04	186	77	4	8f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NELL1 UGT8 NDUFA4 PCDH9	3.09e-04	187	77	4	85e58a312fc325e4063a2d250666b99b8f99beb6
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NELL1 UGT8 NDUFA4 PCDH9	3.09e-04	187	77	4	52b5b38bef3cc06487cf42c6fb22fb33f0c7ce2b
ToppCell	COVID-19-kidney-Mito-rich_Distal\|kidney / Disease (COVID-19 only), tissue and cell type	NELL1 HMCN1 UGT8 PCDH9	3.09e-04	187	77	4	2ce8038d9d1302e850c1bb536e755598f77ba4b9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TROAP AOAH BUB1B CCDC88B	3.09e-04	187	77	4	73931a5ea73799095daff100b5f18853c57c74dc
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NELL1 HMCN1 NYNRIN ROR2	3.15e-04	188	77	4	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NELL1 HMCN1 NYNRIN ROR2	3.15e-04	188	77	4	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NELL1 HMCN1 NYNRIN ROR2	3.15e-04	188	77	4	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NELL1 HMCN1 UGT8 PCDH9	3.15e-04	188	77	4	3cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-cDC2\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AOAH TLR7 DNAH9 LILRA5	3.15e-04	188	77	4	239bec13476dd43bebc2c6eba8d1fe35f2744673
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NELL1 HMCN1 UGT8 PCDH9	3.21e-04	189	77	4	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 TGFBR1 RAB44 LILRA5	3.21e-04	189	77	4	b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCell	Non-neuronal-Non-dividing-OPC-OPC\|World / Primary Cells by Cluster	SCN1A ARC UGT8 PCDH9	3.21e-04	189	77	4	ddf5be73912570c32c50f4ac2902da9b590526f8
ToppCell	Non-neuronal-Non-dividing-OPC\|World / Primary Cells by Cluster	SCN1A ARC UGT8 PCDH9	3.21e-04	189	77	4	13848a031ab896b4b24c8319e4745b9b17ff9cfd
ToppCell	Non-neuronal-Non-dividing-OPC-OPC-30\|World / Primary Cells by Cluster	SCN1A ARC UGT8 PCDH9	3.21e-04	189	77	4	313d165fad541ec6e8dd524b88856e2c93eeb681
ToppCell	Mesenchymal-airway_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	PRUNE2 FLNC ROR2 PTK7	3.28e-04	190	77	4	645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 TGFBR1 RAB44 LILRA5	3.28e-04	190	77	4	da58227565ad6a690828dd8554dd3670222f8582
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	JAK2 PXDN ROR2 LRRK1	3.28e-04	190	77	4	0fea33f2dc1efa23aaa2da1c318482a52a313ff1
Drug	Carisoprodol [78-44-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A	PRUNE2 TGFBR1 DNAH3 ARC RAD54L2 CABIN1 NR0B2	3.94e-06	197	75	7	4955_UP
Drug	Benoxinate hydrochloride [5987-82-6]; Down 200; 11.6uM; PC3; HT_HG-U133A	JAK2 NFX1 UGT8 LRRK1 RAD54L2 ENPEP PCDH9	3.94e-06	197	75	7	3996_DN
Disease	essential thrombocythemia (is_implicated_in)	JAK2 VWF	9.75e-05	6	76	2	DOID:2224 (is_implicated_in)
Disease	cathepsin S measurement	MIA3 GNPTAB	1.81e-04	8	76	2	EFO_0008073
Disease	Colorectal Carcinoma	TGFBR1 NELL1 FLNC DNAH3 DUSP21 BUB1B MSH2 EPHA1	4.48e-04	702	76	8	C0009402
Disease	Colorectal Neoplasms	TGFBR1 FLNC BUB1B MSH2 EPHA1	7.54e-04	277	76	5	C0009404
Disease	respiratory syncytial virus infectious disease (is_marker_for)	TLR7 IL5RA	9.75e-04	18	76	2	DOID:1273 (is_marker_for)
Disease	Lipoidosis	LSS NR0B2	1.09e-03	19	76	2	C0023794
Disease	Autism Spectrum Disorders	SCN1A PCDH9 CA2	1.39e-03	85	76	3	C1510586
Disease	Sarcosine measurement	PCDHGB3 DBH	1.60e-03	23	76	2	EFO_0021668
Disease	Etat Marbre	SCN1A ARC	1.60e-03	23	76	2	C0266487
Disease	aspartate measurement	GNPTAB ENPEP	1.74e-03	24	76	2	EFO_0010462
Disease	Lynch syndrome (is_implicated_in)	TGFBR1 MSH2	1.74e-03	24	76	2	DOID:3883 (is_implicated_in)
Disease	Neurodevelopmental Disorders	SCN1A PTK7 DHX30	1.80e-03	93	76	3	C1535926
Disease	Adenocarcinoma of large intestine	ROR2 MSH2 PTK7	1.98e-03	96	76	3	C1319315
Disease	Alzheimer disease, high density lipoprotein cholesterol measurement	LILRA5 EPHA1	2.04e-03	26	76	2	EFO_0004612, MONDO_0004975
Disease	Movement Disorders	SCN1A ARC	2.54e-03	29	76	2	C0026650
Disease	posterior urethral valve	PCDH9 PTK7	2.54e-03	29	76	2	MONDO_0019640

Protein segments in the cluster

Peptide	Gene	Start	Entry
PRAKENELQAGPWNT	BUB1B	301	O60566
PPKDGWSEQQQILNG	EPHA1	46	P21709
LEGTVRDPAWQKPQQ	CCDC88B	686	A6NC98
PQKQGEPLDQFLWRK	ARC	291	Q7LC44
GDQWVKHRQPLQQKP	DCP2	286	Q8IU60
QRNWQPTLKGDEKPV	RAD54L2	1006	Q9Y4B4
NISWQRPKDIINNPL	CAPN11	106	Q9UMQ6
PGWQEIKGVQQRLQE	DHX30	676	Q7L2E3
NGQELRLAPPVQWAL	C5orf38	96	Q86SI9
WNSPVGNQLDPIQRE	RANBP9	661	Q96S59
LKNWVKELRQHGPPN	RAB22A	96	Q9UL26
QLWGQLRQEEPQLAG	RAB44	171	Q7Z6P3
QLPAPKWAELANLIN	JAK2	771	O60674
KVQLQWPQILGKENP	AOAH	546	P28039
EKGNPPLWLALANNL	ANKFY1	686	Q9P2R3
LPWVKQNINRQGNAP	DNAJC14	401	Q6Y2X3
PWDTQNPLEPKNKAR	LILRA5	86	A6NI73
KNQLIEQFPGIEPWL	MCTS1	26	Q9ULC4
NGQIPSWLNLDNPRV	GNPTAB	351	Q3T906
KLPNQGEDRRVPQNW	MGME1	86	Q9BQP7
QGNQLAALPPQEKWT	LRRK1	481	Q38SD2
NKNWQLLKPPQSLRQ	KY	321	Q8NBH2
KLWNLEPGEVQPQTL	LRRC53	451	A6NM62
PEGEKWPQLIVQQNL	PCDH9	196	Q9HC56
VGAWLQDPANQNLPE	PEX26	141	Q7Z412
PENKVIGQQPQAIDW	CSNKA2IP	581	A0A1B0GTH6
PKQRLLGWIQNKVPQ	FLNC	161	Q14315
NKVPQLPITNFNRDW	FLNC	171	Q14315
CLLEKQLPNGDWPQE	LSS	676	P48449
PKSHGLQNQPWQKLR	NFX1	96	Q12986
NWAPGEPNNRQKDED	SELE	96	P16581
NPQIQNSNKPREWIR	GBP7	211	Q8N8V2
GQWKNFRLPDFVNPV	ENPEP	86	Q07075
QRPKDPNNLLNDWSQ	PSMD12	416	O00232
GNLQKQAPPNTDWRF	PCDHGB3	801	Q9Y5G1
VKWQQLNPDVPEALQ	PARP4	1056	Q9UKK3
FWQLPPQDQRRLLQG	NR0B2	76	Q15466
NLPPGINLWLGQRNQ	NELL1	181	Q92832
APRNSWQKDGQPLLE	HMCN1	2901	Q96RW7
QNPNAFQPWELLGVL	GPRC6A	436	Q5T6X5
DRKNNPEPWNRLSPN	NDUFA4L2	51	Q9NRX3
VRKALNIPEQLPQWD	CTSA	346	P10619
WEDPRSQGQLNEKPL	ITCH	466	Q96J02
VLLQWKPNPDQEQRN	IL5RA	46	Q01344
PPQRDPNWNGERLNK	CASC3	266	O15234
LKQWRGELPPELVQQ	CABIN1	1161	Q9Y6J0
GKLPLQPQEFWDVIQ	DNAH3	376	Q8TD57
NVLLEQGKAKNPWPN	CS	386	O75390
PLPEDLQRWVNGANE	UGT8	271	Q16880
LGNNTKLIEWLPQND	UGT8	331	Q16880
VRFQGEWNLQPLPKV	DBH	571	P09172
VRNEDKWKPLNNPRN	C2orf66	41	Q6UXQ4
VLPVLANEKNRLNWP	DNAH9	141	Q9NYC9
WVRNGAAQPLDQPQE	SAAL1	221	Q96ER3
PQGQRLVNQWIKQPL	MSH2	336	P43246
PIIRPNNGFWEQLIN	DUSP21	141	Q9H596
NGQRSLELWPRPQQA	LIPE	626	Q05469
GQNPLPLNLEWKQKE	NYNRIN	406	Q9P2P1
ALGPEKQVRNEPWNI	TATDN3	221	Q17R31
KLQLQPQWQPKPRQE	SUPT20HL1	731	Q3ZLR7
KNSHEQLWNIQPRQP	PRUNE2	1901	Q8WUY3
DEVPILGRNLPWQQE	MIA3	646	Q5JRA6
DRNNPEPWNKLGPND	NDUFA4	46	O00483
RDNQWNPRQSEVPKP	PRRC2C	1371	Q9Y520
TQQQLLPGVKDPNLW	SUPT5H	166	O00267
PNVRWLKNDAPVVQE	ROR2	91	Q01974
QDSWKEAPAPRGNLQ	SEC31B	991	Q9NQW1
GNLRNKCIQWPPTNA	SCN1A	271	P35498
CEQKLRPNIPNRWQS	TGFBR1	446	P36897
VDNWRPAQPLKNRQI	CA2	241	P00918
GPNDALLRWPFNQKV	TRAF2	416	Q12933
GPNANVQELERIGWP	VWF	1631	P04275
LAQKLQGLENWGQDP	PBXIP1	436	Q96AQ6
NLNIQLKWKRPPENE	PIGT	331	Q969N2
GNPKPEIIWLRNNNE	PXDN	271	Q92626
NDFQKLLGDINWIQP	ERVK-8	266	P63133
DQENQDPRRWVQKPP	TROAP	41	Q12815
DWQPRENPFQNLKVL	TP53BP1	1861	Q12888
RDWLPGQPVLENLSQ	TLR7	931	Q9NYK1
KEDPRIGNLWIQNPF	ZBED9	1196	Q6R2W3
AQLLWLGPQQQKVDP	VSIG10L2	531	P0DP72
PQPRQDVLNWLNEEK	PPP6R3	176	Q5H9R7
LQCEAQGDPKPLIQW	PTK7	611	Q13308