Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessWnt receptor catabolic process

RNF43 ZNRF3

3.19e-0521172GO:0038018
GeneOntologyBiologicalProcessWnt signaling pathway

APC2 PLEKHA4 APC KLF15 RNF213 WNT4 RNF43 CELSR1 SULF2 ZNRF3 NFATC4 LRP4

3.75e-0551611712GO:0016055
GeneOntologyBiologicalProcessregulation of Wnt signaling pathway

APC2 PLEKHA4 APC KLF15 RNF213 RNF43 SULF2 ZNRF3 NFATC4 LRP4

4.75e-0536811710GO:0030111
GeneOntologyCellularComponentcytoplasmic microtubule

RIBC2 GTSE1 APC2 APC SAA1 SAA2

9.91e-051331166GO:0005881
DomainIG

HSPG2 PAPLN MDGA2 TYRO3 LSR HMCN2 KIR2DL5A KIR2DL4 ROBO3 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1 IL6R

1.43e-0742110814SM00409
DomainIg_sub

HSPG2 PAPLN MDGA2 TYRO3 LSR HMCN2 KIR2DL5A KIR2DL4 ROBO3 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1 IL6R

1.43e-0742110814IPR003599
Domainig

HSPG2 MDGA2 TYRO3 KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1 IL6R

1.53e-0719010810PF00047
DomainImmunoglobulin

HSPG2 MDGA2 TYRO3 KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1 IL6R

1.53e-0719010810IPR013151
DomainIg-like_fold

PAPPA2 HSPG2 POGLUT3 PAPLN MDGA2 TYRO3 LSR HMCN2 NFATC4 KIR2DL5A KIR2DL4 ROBO3 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1 IL6R

6.00e-0770610817IPR013783
DomainIg-like_dom

HSPG2 PAPLN MDGA2 TYRO3 LSR HMCN2 KIR2DL5A KIR2DL4 ROBO3 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1 IL6R

1.21e-0650310814IPR007110
DomainIG_LIKE

HSPG2 PAPLN MDGA2 TYRO3 LSR HMCN2 KIR2DL5A KIR2DL4 ROBO3 KIR2DS3 KIR2DS5 KIR3DL1 IL6R

5.18e-0649110813PS50835
Domain-

PAPPA2 HSPG2 POGLUT3 PAPLN MDGA2 TYRO3 LSR NFATC4 KIR2DL5A KIR2DL4 ROBO3 KIR2DS3 KIR3DL1 KIR3DS1 IL6R

6.28e-06663108152.60.40.10
DomainAPC_r

APC2 APC

3.31e-0521082PF05923
DomainSAMP

APC2 APC

3.31e-0521082PF05924
DomainCyt_c_oxidase_su6a

COX6A1 COX6A2

3.31e-0521082PD006036
Domain-

COX6A1 COX6A2

3.31e-05210824.10.95.10
DomainCyt_c_oxidase_su6a_CS

COX6A1 COX6A2

3.31e-0521082IPR018507
DomainCyt_c_oxidase_su6a

COX6A1 COX6A2

3.31e-0521082IPR001349
DomainAPC_dom

APC2 APC

3.31e-0521082IPR026831
DomainAPC_N

APC2 APC

3.31e-0521082IPR032038
DomainCOX6A

COX6A1 COX6A2

3.31e-0521082PS01329
DomainAPC_basic_dom

APC2 APC

3.31e-0521082IPR009234
DomainApc_fam

APC2 APC

3.31e-0521082IPR026818
DomainAPC_rpt

APC2 APC

3.31e-0521082IPR009223
DomainSAMP

APC2 APC

3.31e-0521082IPR009224
DomainAPC_basic

APC2 APC

3.31e-0521082PF05956
DomainAPC_N_CC

APC2 APC

3.31e-0521082PF16689
DomainCOX6A

COX6A1 COX6A2

3.31e-0521082PF02046
DomainEGF_CA

HSPG2 JAG2 THBS2 CELSR1 HMCN2 LRP4

7.63e-051221086SM00179
DomainEGF-like_Ca-bd_dom

HSPG2 JAG2 THBS2 CELSR1 HMCN2 LRP4

8.35e-051241086IPR001881
DomainSAA

SAA1 SAA2

1.97e-0441082PS00992
DomainSAA

SAA1 SAA2

1.97e-0441082SM00197
DomainSAA

SAA1 SAA2

1.97e-0441082PF00277
DomainNUT

NUTM2A NUTM2B

3.28e-0451082IPR024310
DomainNUT_N

NUTM2A NUTM2B

3.28e-0451082IPR024309
DomainNUT

NUTM2A NUTM2B

3.28e-0451082PF12881
DomainPAN_AP

MST1 MST1L

3.28e-0451082SM00473
DomainSerum_amyloid_A

SAA1 SAA2

3.28e-0451082IPR000096
DomainLaminin_G

HSPG2 COL18A1 THBS2 CELSR1

3.53e-04581084IPR001791
DomainIGc2

HSPG2 PAPLN MDGA2 TYRO3 HMCN2 ROBO3 IL6R

4.33e-042351087SM00408
DomainIg_sub2

HSPG2 PAPLN MDGA2 TYRO3 HMCN2 ROBO3 IL6R

4.33e-042351087IPR003598
DomainPan_app

MST1 MST1L

6.83e-0471082IPR003609
DomainPAN

MST1 MST1L

6.83e-0471082PS50948
DomainPAN_1

MST1 MST1L

6.83e-0471082PF00024
DomainEGF

HSPG2 JAG2 THBS2 CELSR1 LRP4

8.26e-041261085PF00008
DomainIg_I-set

HSPG2 PAPLN MDGA2 TYRO3 HMCN2 ROBO3

8.30e-041901086IPR013098
DomainI-set

HSPG2 PAPLN MDGA2 TYRO3 HMCN2 ROBO3

8.30e-041901086PF07679
DomainGPS

PKD1L1 ADGRB1 CELSR1

1.17e-03361083PS50221
DomainGPS

PKD1L1 ADGRB1 CELSR1

1.27e-03371083IPR000203
DomainFN3_dom

PAPPA2 MDGA2 TYRO3 TRIL ROBO3 IL6R

1.36e-032091086IPR003961
DomainEGF_CA

JAG2 THBS2 HMCN2 LRP4

1.56e-03861084PF07645
DomainConA-like_dom

PAPPA2 HSPG2 MDGA2 COL18A1 THBS2 CELSR1

1.72e-032191086IPR013320
DomainZF_RING_2

RNF213 RNF43 KMT2C RNF113B BRCA1 ZNRF3 NFXL1

1.73e-032981087PS50089
DomainGAIN_dom_N

ADGRB1 CELSR1

1.76e-03111082IPR032471
DomainGAIN

ADGRB1 CELSR1

1.76e-03111082PF16489
DomainLamG

HSPG2 COL18A1 CELSR1

2.10e-03441083SM00282
DomainGrowth_fac_rcpt_

HSPG2 JAG2 CELSR1 HMCN2 LRP4

2.13e-031561085IPR009030
Domain-

PAPPA2 HSPG2 THBS2 CELSR1

2.25e-039510842.60.120.200
DomainEGF_3

HSPG2 JAG2 THBS2 CELSR1 HMCN2 LRP4

2.45e-032351086PS50026
DomainASX_HYDROXYL

JAG2 CELSR1 HMCN2 LRP4

2.71e-031001084PS00010
DomainZnf_RING

RNF213 RNF43 KMT2C RNF113B BRCA1 ZNRF3 NFXL1

2.87e-033261087IPR001841
DomainEGF-like_dom

HSPG2 JAG2 THBS2 CELSR1 HMCN2 LRP4

3.26e-032491086IPR000742
DomainEGF-type_Asp/Asn_hydroxyl_site

JAG2 CELSR1 HMCN2 LRP4

3.34e-031061084IPR000152
DomainEGF_1

HSPG2 JAG2 THBS2 CELSR1 HMCN2 LRP4

3.67e-032551086PS00022
DomainSulfatase_CS

ARSG SULF2

3.77e-03161082IPR024607
DomainEGF-like_CS

HSPG2 JAG2 THBS2 CELSR1 HMCN2 LRP4

4.10e-032611086IPR013032
DomainSULFATASE_1

ARSG SULF2

4.26e-03171082PS00523
DomainKringle_CS

MST1 MST1L

4.26e-03171082IPR018056
DomainKRINGLE_1

MST1 MST1L

4.26e-03171082PS00021
DomainKR

MST1 MST1L

4.26e-03171082SM00130
DomainKringle

MST1 MST1L

4.26e-03171082IPR000001
DomainKRINGLE_2

MST1 MST1L

4.26e-03171082PS50070
DomainKringle

MST1 MST1L

4.26e-03171082PF00051
DomainSULFATASE_2

ARSG SULF2

4.26e-03171082PS00149
DomainEGF_2

HSPG2 JAG2 THBS2 CELSR1 HMCN2 LRP4

4.42e-032651086PS01186
DomainSulfatase

ARSG SULF2

4.77e-03181082PF00884
DomainSulfatase_N

ARSG SULF2

4.77e-03181082IPR000917
DomainGPCR_2_secretin-like

ADGRB1 CELSR1 SMO

5.07e-03601083IPR000832
DomainGPCR_2-like

ADGRB1 CELSR1 SMO

5.07e-03601083IPR017981
DomainG_PROTEIN_RECEP_F2_4

ADGRB1 CELSR1 SMO

5.31e-03611083PS50261
DomainBRCT

BRCA1 REV1

5.31e-03191082PF00533
Pubmed

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.

KIR2DL5B KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

8.68e-1417119720878400
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.

KIR2DL5B KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

8.68e-1417119720650299
Pubmed

[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].

KIR2DL5B KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

8.68e-1417119719218127
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.

KIR2DL5B KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

8.68e-1417119719450876
Pubmed

Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.

KIR2DL5B KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

8.68e-1417119719761533
Pubmed

Compound KIR-HLA genotype analyses in the Iranian population by a novel PCR-SSP assay.

KIR2DL5B KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

3.43e-1320119720193031
Pubmed

HLA and KIR frequencies in Sicilian Centenarians.

KIR2DL5B KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

3.43e-1320119720426625
Pubmed

Distribution of KIR genes in the population of unrelated individuals homozygous for ancestral haplotype AH8.1 (HLA-A1B8DR3).

KIR2DL5B KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

7.50e-1322119720492596
Pubmed

Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.28e-1212119620371502
Pubmed

Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.

KIR2DL5B KIR2DL5A KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

2.38e-1213119619120281
Pubmed

Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

4.15e-1214119619875891
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

4.15e-1214119615896204
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

6.89e-1215119620082646
Pubmed

[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

6.89e-1215119620356536
Pubmed

Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

6.89e-1215119619926642
Pubmed

Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

6.89e-1215119620643584
Pubmed

Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

6.89e-1215119619326408
Pubmed

Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-1116119619897003
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-1116119619000141
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-1116119620670355
Pubmed

Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-1116119618668235
Pubmed

Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-1116119619309280
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptors gene family in Zhejiang Han population].

KIR2DL5B KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1

1.10e-1116119616403292
Pubmed

Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-1116119619527230
Pubmed

Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-1116119620652381
Pubmed

Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-1116119619279038
Pubmed

No association of KIR genes with Behcet's disease.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-1116119617868255
Pubmed

A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-1116119618643961
Pubmed

Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-1116119620331834
Pubmed

HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-1116119620210919
Pubmed

[Effects of killer immunoglobulin-like receptor and human leukocyte antigen class I ligand on the prognosis of related donor hematopoietic stem cell transplantation].

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.70e-1117119619968064
Pubmed

Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.70e-1117119619032228
Pubmed

The role of killer immunoglobulin-like receptor haplotypes on the outcome of unrelated donor haematopoietic SCT for thalassaemia.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.70e-1117119620173792
Pubmed

Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.70e-1117119620483367
Pubmed

KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.70e-1117119619169284
Pubmed

Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

2.54e-1118119619630074
Pubmed

Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes.

KIR2DL5B KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1

2.54e-1118119620200544
Pubmed

Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

2.54e-1118119619046302
Pubmed

Association of killer cell immunoglobulin-like receptors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diabetes.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

2.54e-1118119620580654
Pubmed

Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

2.54e-1118119620519398
Pubmed

Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

2.54e-1118119619846535
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

2.54e-1118119620210918
Pubmed

Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.

KIR2DL5B KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

2.85e-1135119719683555
Pubmed

KIR and HLA gene combinations in Vogt-Koyanagi-Harada disease.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

3.70e-1119119618571006
Pubmed

Association between killer-cell immunoglobulin-like receptor genotypes and leprosy in Brazil.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

3.70e-1119119618778326
Pubmed

Associations between genes for killer immunoglobulin-like receptors and their ligands in patients with solid tumors.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

3.70e-1119119620600442
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Southern Brazilian population from the state of Paraná.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

3.70e-1119119618848853
Pubmed

Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

7.35e-1121119619861144
Pubmed

Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus.

KIR2DL5B KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.07e-1010119521206914
Pubmed

Killer-cell immunoglobulin-like receptors (KIR) in severe A (H1N1) 2009 influenza infections.

KIR2DL5B KIR2DL5A KIR2DS5 KIR3DS1

1.30e-104119422652695
Pubmed

Activating KIR genes are associated with ankylosing spondylitis in Asian populations.

KIR2DL5A KIR2DS5 KIR3DL1 KIR3DS1

1.30e-104119418638658
Pubmed

Natural killer cells and immune surveillance.

KIR2DL5A KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.96e-1011119518830515
Pubmed

[Genotype analysis of killer cell immunoglobulin-like receptors in Graves' disease patients].

KIR2DL5A KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.96e-1011119519664392
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia].

KIR2DL5A KIR2DL4 KIR2DS5 KIR3DL1 KIR3DS1

3.35e-1012119517490516
Pubmed

Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations.

KIR2DL5A KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

3.35e-1012119519936734
Pubmed

[Relationship between CMV reactivation and KIR haplotype/HLA-Cw genotype in patients after unrelated-donor hematopoietic stem cell transplantation.].

KIR2DL5A KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

3.35e-1012119520137308
Pubmed

[Study on the polymorphism of killer cell immunoglobulin like receptor (KIR) gene with systemic lupus erythematosus of North population in China].

KIR2DL5A KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

5.42e-1013119518687225
Pubmed

Immunogenetic characteristics of patients with autoimmune gastritis.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

6.29e-1029119620082482
Pubmed

[Genotype and haplotype analysis of killer cell immunoglobulin-like receptors in ankylosing spondylitis].

KIR2DL5A KIR2DL4 KIR2DS3 KIR3DL1 KIR3DS1

8.42e-1014119519489269
Pubmed

Multiple sclerosis associates with LILRA3 deletion in Spanish patients.

KIR2DL5A KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

8.42e-1014119519421224
Pubmed

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.

KIR2DL5A KIR2DL4 KIR2DS5 KIR3DL1 KIR3DS1

8.42e-1014119518945962
Pubmed

Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis, with and without axial spondyloarthropathy.

KIR2DL5A KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.26e-0915119519850842
Pubmed

Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma.

KIR2DL5A KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.26e-0915119520207982
Pubmed

Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia.

KIR2DL5A KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.26e-0915119519493232
Pubmed

KIR genes polymorphism in Argentinean Caucasoid and Amerindian populations.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1

1.26e-0915119517498266
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphism in lymphoproliferative diseases of granular lymphocytes in a Japanese population.

KIR2DL5A KIR2DS3 KIR3DL1 KIR3DS1

1.94e-096119420528243
Pubmed

The beneficial impact of missing KIR ligands and absence of donor KIR2DS3 gene on outcome following unrelated hematopoietic SCT for myeloid leukemia in the Chinese population.

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DS1

2.58e-0917119520173784
Pubmed

Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors.

KIR2DL4 KIR2DS3 KIR3DL1 KIR3DS1

4.52e-09711949430220
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HSPG2 SPHK2 WWP1 GTSE1 COX6A1 C15orf39 PAPLN ECE1 RNF43 ARSG JAG2 NHSL1 KMT2C CELSR1 ZNRF3 AHNAK HELZ2 LRP4 AGAP3

7.24e-0911051191935748872
Pubmed

KIR haplotype content at the allele level in 77 Northern Irish families.

KIR2DL5A KIR2DL4 KIR3DL1 KIR3DS1

9.02e-098119417200871
Pubmed

Human diversity in killer cell inhibitory receptor genes.

KIR2DL4 KIR2DS3 KIR3DL1 KIR3DS1

9.02e-09811949430221
Pubmed

Polymorphisms of killer cell immunoglobulin-like receptor gene: possible association with susceptibility to or clearance of hepatitis B virus infection in Chinese Han population.

KIR2DL5A KIR2DL4 KIR2DS3 KIR3DS1

1.62e-089119418074414
Pubmed

Alternatively spliced forms of human killer inhibitory receptors.

KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.62e-08911948662091
Pubmed

Assessment of killer cell immunoglobulinlike receptor expression and corresponding HLA class I phenotypes demonstrates heterogenous KIR expression independent of anticipated HLA class I ligands.

KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1

2.69e-0810119412559621
Pubmed

Killer-cell immunoglobulin-like receptors and falciparum malaria in southwest Nigeria.

KIR2DL5A KIR2DS3 KIR2DS5

3.91e-083119324929143
Pubmed

Multiple copies of KIR 3DL/S1 and KIR 2DL4 genes identified in a number of individuals.

KIR2DL4 KIR3DL1 KIR3DS1

3.91e-083119312826375
Pubmed

Killer immunoglobulin-like receptor genotype may distinguish immunodeficient HIV-infected patients resistant to immune restoration diseases associated with herpes virus infections.

KIR2DL5A KIR2DS5 KIR3DS1

3.91e-083119317592337
Pubmed

Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome.

KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

6.31e-0812119419181658
Pubmed

KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

9.10e-0813119419934297
Pubmed

Killer immunoglobulin-like receptor gene repertoire influences viral load of primary human cytomegalovirus infection in renal transplant patients.

KIR2DL5A KIR2DS5 KIR3DS1

1.56e-074119325253288
Pubmed

Polymorphism and domain variability of human killer cell inhibitory receptors.

KIR2DL4 KIR3DL1 KIR3DS1

1.56e-07411939059894
Pubmed

The silent KIR3DP1 gene (CD158c) is transcribed and might encode a secreted receptor in a minority of humans, in whom the KIR3DP1, KIR2DL4 and KIR3DL1/KIR3DS1 genes are duplicated.

KIR2DL4 KIR3DL1 KIR3DS1

1.56e-074119315580659
Pubmed

Recombinant structures expand and contract inter and intragenic diversification at the KIR locus.

KIR2DL5A KIR2DS3 KIR3DS1

1.56e-074119323394822
Pubmed

Investigation of killer cell immunoglobulin-like receptor (KIR) gene diversity: KIR2DL2, KIR2DL5 and KIR2DS5.

KIR2DL5B KIR2DL5A KIR2DS5

1.56e-074119318498296
Pubmed

KIR gene in ethnic and Mestizo populations from Mexico.

KIR2DL5A KIR2DS5 KIR3DS1

3.89e-075119316698429
Pubmed

Association of killer cell immunoglobulin-like receptor genotypes with microscopic polyangiitis.

KIR2DS3 KIR3DL1 KIR3DS1

3.89e-075119316508981
Pubmed

A Nedd4 E3 Ubiquitin Ligase Pathway Inhibits Robo1 Repulsion and Promotes Commissural Axon Guidance across the Midline.

WWP1 NEDD4 ROBO3

3.89e-075119336002265
Pubmed

Endothelial Cyp26b1 restrains murine heart valve growth during development.

WNT4 ECE1 TRIL BMP3 COL18A1 THBS2 NFATC4

1.57e-06163119735364055
Pubmed

NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.

APC RNF43 ZNRF3

2.16e-068119334079124
Pubmed

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.

KIR2DS3 KIR2DS5 KIR3DL1

3.23e-06911937749980
Pubmed

Combination of KIR and HLA gene variants augments the risk of developing birdshot chorioretinopathy in HLA-A*29-positive individuals.

KIR2DS3 KIR3DL1 KIR3DS1

3.23e-069119318340360
Pubmed

R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors.

WNT4 RNF43 CRYM ZNRF3

3.33e-0630119432324134
Pubmed

Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1.

WWP1 NEDD4 BRCA1

6.32e-0611119317996703
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

RIBC2 ABCA12 WWP1 RNF213 RNF43 PHF2 SULF2 HMCN2 BRCA1 ZNRF3 ZBTB10 LRP4 USP54 GARRE1 AGAP3

6.59e-0611161191531753913
Pubmed

Polymorphisms in the SAA1/2 gene are associated with carotid intima media thickness in healthy Han Chinese subjects: the Cardiovascular Risk Survey.

SAA1 SAA2

1.16e-052119221103356
Pubmed

The rate and significance of type 1/type 2 serum amyloid A protein gene polymorphisms in patients with ankylosing spondylitis and amyloidosis.

SAA1 SAA2

1.16e-052119226300108
Pubmed

RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis.

RNF43 ZNRF3

1.16e-052119227661107
Pubmed

DNA sequence evidence for polymorphic forms of human serum amyloid A (SAA).

SAA1 SAA2

1.16e-05211923800865
Pubmed

Short stature with low insulin-like growth factor 1 availability due to pregnancy-associated plasma protein A2 deficiency in a Saudi family.

PAPPA2 IGF1

1.16e-052119234272725
Pubmed

BRCA1 negatively regulates IGF-1 expression through an estrogen-responsive element-like site.

IGF1 BRCA1

1.16e-052119222739988
Cytoband19q13.4

ZNF135 MZF1 KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

1.63e-0979119719q13.4
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF135 SPHK2 GPATCH1 PLEKHA4 NCCRP1 ZNF585B LSR MZF1 KIR2DL4 RINL KIR3DL1 GARRE1

6.59e-05119211912chr19q13
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR2DL5B KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1 KIR3DS1

4.87e-1318757620
GeneFamilyImmunoglobulin like domain containing

HSPG2 MDGA2 TYRO3 LSR HMCN2 ROBO3 IL6R

1.52e-05193757594
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

HSPG2 PAPLN MDGA2 TYRO3 HMCN2 ROBO3

5.51e-05161756593
GeneFamilyDoublecortin superfamily

RP1L1 DCLK3

7.48e-04107521369
GeneFamilySulfatases

ARSG SULF2

2.49e-0318752410
GeneFamilyMitochondrial complex IV: cytochrome c oxidase subunits

COX6A1 COX6A2

2.77e-0319752643
CoexpressionKAZMIN_PBMC_P_FALCIPARUM_RTSS_AS01_AGE_UNKNOWN_CORRELATED_WITH_PROTECTION_56DY_NEGATIVE

KIR2DL5A KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1

2.65e-06491175M40909
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL1

IQANK1 KLF15 DNAH7 COL18A1 CELSR1 SULF2 BRCA1 AHNAK ARHGEF26 ODAD3

5.64e-0636411710M39057
CoexpressionKRAS.DF.V1_DN

PAPPA2 PGLYRP4 KLF15 RNF43 ZNF764 KIR2DL5A ROBO3

2.64e-051931177M2861
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLF15 PAPLN RNF43 NHSL1 TRIL NFATC4 AHNAK LRP4

2.78e-08186114873cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLF15 PAPLN RNF43 NHSL1 NFATC4 AHNAK LRP4 ARHGEF26

2.90e-0818711485d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLF15 PAPLN RNF43 NHSL1 NFATC4 AHNAK LRP4 ARHGEF26

2.90e-0818711485c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLF15 PAPLN RNF43 NHSL1 TRIL NFATC4 AHNAK LRP4

3.28e-08190114878cc6c28b31de041c24175a98f47da256ecc15a2
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLF15 PAPLN RNF43 NHSL1 TRIL NFATC4 AHNAK LRP4

3.28e-081901148e67d9400467b438592690b23d681e6c2fb8f09fd
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLF15 PAPLN NHSL1 TRIL NFATC4 AHNAK LRP4 ARHGEF26

3.28e-081901148b56c55f608b30f7379941ac7d5f0f5200f305fca
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IQANK1 RIBC2 GTSE1 NHSL1 CELSR1 PALM3 ODAD3

2.96e-0717111471854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCellfacs-Skin-nan-24m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT4 JAG2 BMP3 THBS2 CELSR1 LRP4 IL6R

3.46e-07175114721542be95059983d2c8bdf01ec711fdbf1ec1f62
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|390C / Donor, Lineage, Cell class and subclass (all cells)

PGLYRP4 WNT4 SAA1 SAA2 CRYM PALM3 INAVA

3.88e-071781147fce60ce6b662f1bdaa3b4da43800c6c22fe89533
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|390C / Donor, Lineage, Cell class and subclass (all cells)

PGLYRP4 WNT4 SAA1 SAA2 CRYM PALM3 INAVA

3.88e-071781147b19c906e067b07eadfd68934d9330b447e24c708
ToppCellfacs-Skin-Anagen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP3 THBS2 CELSR1 ZNRF3 LRP4 QARS1 IL6R

4.51e-07182114722d6f4790950508e8aa27e02a8133af5f53f13c8
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLF15 PAPLN RNF43 NHSL1 AHNAK LRP4 ARHGEF26

5.22e-07186114741e03be964044dae690d566bd078dab3d8045eba
ToppCellThalamus-Endothelial|Thalamus / BrainAtlas - Mouse McCarroll V32

HSPG2 TNS2 ECE1 LSR NFATC4 AHNAK HELZ2

5.22e-071861147dcc6e4417c4123d5ca6b96fa8ca4874626aaebdb
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLF15 PAPLN NHSL1 NFATC4 AHNAK LRP4 ARHGEF26

5.41e-07187114793c78fc7f126132eb84feb47be2c4e8c568b9e91
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN NHSL1 TRIL NFATC4 AHNAK LRP4 ARHGEF26

6.03e-0719011473a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN NHSL1 TRIL NFATC4 AHNAK LRP4 ARHGEF26

6.03e-0719011471c3d601422efa60fad8565f9ccd9032b847e4a91
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN RNF43 NHSL1 NFATC4 AHNAK LRP4 ARHGEF26

6.46e-071921147f7e4509003d71f805b9d4587098e90d2897b6739
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN RNF43 NHSL1 NFATC4 AHNAK LRP4 ARHGEF26

6.46e-071921147705ce805cb00a53793b57bcf466d0fbec590a83c
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN NHSL1 TRIL NFATC4 AHNAK LRP4 ARHGEF26

6.69e-071931147b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN NHSL1 TRIL NFATC4 AHNAK LRP4 ARHGEF26

6.69e-07193114740edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RNF43 TRIL COL18A1 LRP4 INAVA KIR3DL1

1.22e-06133114663d2f096ae47d9b587acc6c5fbd346e5e58842b8
ToppCellBasal_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

MDGA2 WNT4 NUDT9 JAG2 HMCN2 SMO

3.33e-06158114651e3ed1b91b010404d66e3e7efdbffc0c815e25b
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF15 NCCRP1 CELSR1 IGF1 LRP4 ARHGEF26

5.60e-061731146c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF15 NCCRP1 CELSR1 IGF1 LRP4 ARHGEF26

5.60e-061731146f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN NHSL1 TRIL NFATC4 AHNAK LRP4

6.60e-0617811464813d6509738f088c12ebf395b70d496af04649a
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN RNF43 NHSL1 NFATC4 AHNAK LRP4

7.26e-0618111460c3f469bed108994ed696230e3c30343f7a301d3
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 RNF43 CELSR1 USP54 ARHGEF26 MOCOS

7.97e-06184114642ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN NHSL1 NFATC4 AHNAK LRP4 ARHGEF26

8.74e-061871146dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN NHSL1 NFATC4 AHNAK LRP4 ARHGEF26

8.74e-0618711464d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN NHSL1 NFATC4 AHNAK LRP4 ARHGEF26

8.74e-061871146ae90c263f80c36a410150d499e268d198944a3d9
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN NHSL1 NFATC4 AHNAK LRP4 ARHGEF26

8.74e-0618711462b1b2c3792d6c9ab69675ce88842bb589414b530
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN NHSL1 GSDMD AHNAK LRP4 ARHGEF26

8.74e-061871146401be371b32066db926de3415bb4ce9465749dc3
ToppCellfacs-Skin-Telogen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NHSL1 BMP3 THBS2 ZNRF3 LRP4 IL6R

9.01e-0618811468cc927b4c51d982fdafa04dc7393617ad9bb220e
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|343B / Donor, Lineage, Cell class and subclass (all cells)

PGLYRP4 SAA1 SAA2 CRYM PALM3 INAVA

9.29e-061891146b06471b1bebb990d5146bddfb8002401c6b099a0
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|343B / Donor, Lineage, Cell class and subclass (all cells)

PGLYRP4 SAA1 SAA2 CRYM PALM3 INAVA

9.29e-061891146a8246acf31f02c85421268245afb651aa8788f14
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN RNF43 NHSL1 NFATC4 LRP4 ARHGEF26

9.57e-0619011465c64b727669b23d2a23c8ad1d5d6caab7af37d56
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN NHSL1 TRIL NFATC4 LRP4 ARHGEF26

1.02e-05192114643beaac1de99b9c1a6dab4a450b4e81286987b64
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PGLYRP4 ECE1 SAA1 SAA2 CRYM INAVA

1.05e-0519311468ede7038a222c7e7ecaf7e86520823cf606cbee7
ToppCellfacs-Pancreas-Exocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 COL18A1 CELSR1 IGF1 AHNAK ARHGEF26

1.05e-051931146c3161a14a40323a58aa202c8a1d6ea0e9c2b9814
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PGLYRP4 ECE1 SAA1 SAA2 CRYM INAVA

1.05e-0519311460e7d7adfaa7191e34038fcda6677561ae13934eb
ToppCellMesenchymal_cells-Stromal_fibro.|World / Lineage and Cell class

HSPG2 COL18A1 SAA1 SAA2 IGF1 AHNAK

1.11e-05195114669723b06c2a5c2aaf4d10874b11bca7f06822bdc
ToppCellBiopsy_Other_PF-Epithelial-MUC5AC+_High|Biopsy_Other_PF / Sample group, Lineage and Cell type

PGLYRP4 NCCRP1 BMP3 SAA1 SAA2 CRYM

1.21e-05198114630e6177e216f66caddcd009fafef0e07369f4d8e
ToppCellFibroblasts-HLA-DRA_high_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

HSPG2 PLEKHA4 COL18A1 THBS2 SULF2 NFATC4

1.21e-051981146e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCellmedial-2-Epithelial-Mucous|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PGLYRP4 NCCRP1 BMP3 SAA1 SAA2 CRYM

1.25e-0519911464737250b7ffa7cc19eb6b057d35d78f13b1afe66
ToppCellmedial-2-Epithelial-Alveolar_Epithelial_Type_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HSPG2 PALM3 INAVA ARHGEF26 IL6R GPRIN2

1.25e-051991146456460c761e26ed4b1d88d9bee4d2a7c9bd9d416
ToppCellmedial-Epithelial-Alveolar_Epithelial_Type_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HSPG2 PALM3 INAVA ARHGEF26 IL6R GPRIN2

1.25e-0519911465263338242f95c04690d0795749ccc20b0d19f7a
ToppCellmedial-Epithelial-Mucous|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PGLYRP4 NCCRP1 BMP3 SAA1 SAA2 CRYM

1.25e-0519911464385963ab25b5378e7964b984028c25b27e5794e
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Club|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PGLYRP4 WNT4 SAA1 SAA2 CRYM PALM3

1.25e-0519911462b17694cffbec28a2c8f165dfcff6bab94aa0f4c
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Club|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

PGLYRP4 WNT4 SAA1 SAA2 CRYM PALM3

1.25e-051991146111cfd589ec6795075d8d88d7664bfb23eba5bf6
ToppCellmedial-Epithelial-Alveolar_Epithelial_Type_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HSPG2 PALM3 INAVA ARHGEF26 IL6R GPRIN2

1.25e-051991146c11365653c69a5dfb37946231f8af05149a61a71
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Club-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PGLYRP4 WNT4 SAA1 SAA2 CRYM PALM3

1.25e-051991146d583290a1d288b749ad17bc501c1487268c6551c
ToppCelldistal-2-Epithelial-Mucous|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PGLYRP4 NCCRP1 BMP3 SAA1 SAA2 CRYM

1.25e-051991146c0275b5011c2bb08e873955afe2e213ec8070d0e
ToppCelldistal-Epithelial-Mucous-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PGLYRP4 WNT4 NCCRP1 SAA1 SAA2 CRYM

1.25e-0519911460af89ef40807fc4ad79ab82a2186ab6e866c6931
ToppCellmedial-Epithelial-Mucous-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PGLYRP4 NCCRP1 BMP3 SAA1 SAA2 CRYM

1.25e-05199114653198bcf5f2f012a3ed1600d95c0923d6976a099
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Dividing_Basal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GTSE1 WNT4 SAA1 SAA2 CELSR1 CRYM

1.25e-051991146f0c289523957258d16135c04679db379d43d28d9
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HSPG2 CPAMD8 ECE1 JAG2 SULF2 GARRE1

1.28e-052001146ac6b8bc9998d303f788511b8f111e682ea9f3df8
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ECE1 RNF43 LSR CELSR1 USP54 ARHGEF26

1.28e-052001146ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

RNF43 LSR CELSR1 PALM3 ARHGEF26 MOCOS

1.28e-0520011468683445ad5b70748c4a1f12eb77d47623085147e
ToppCellParenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HSPG2 TRIL NFATC4 LRP4 USP54 RINL

1.28e-0520011468a4c210a3130f7baedf15ecbc0f4903b97da0352
ToppCellhealthy_donor-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)|healthy_donor / Disease condition, Lineage, Cell class and subclass

HSPG2 RNF43 ZNF764 HELZ2 GPRIN2

2.83e-05138114597f5dc17522462133e582b508ad0ef036e656872
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PKD1L1 RNF43 TRIL LRP4 INAVA

2.93e-051391145a957ea4e581646c76b16b6a7f89579b8c7ac35b6
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CPAMD8 POGLUT3 JAG2 COL18A1 CELSR1

4.22e-05150114598fdc6bdfde84d680e11d8727502b79afbf64303
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TRIL CRYM KLHDC1 GSDMD ODAD3

4.79e-051541145e65e4636646164610f33f7bbac0d879a3ea55986
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

POGLUT3 RNF43 HELZ2 ARHGEF26 AGAP3

5.25e-0515711454183dbed6b31ebe13ef33eb19ba6d0fb4f625953
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TYRO3 FCHSD2 OXA1L TINF2 MAN1B1

5.41e-0515811456d2709b387945c015faa223c20d22b52a4082140
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB1 KLF15 C15orf39 TYRO3 ARHGEF26

5.57e-051591145fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB1 KLF15 C15orf39 TYRO3 ARHGEF26

5.57e-051591145aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB1 KLF15 C15orf39 TYRO3 ARHGEF26

5.57e-0515911458bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCellPBMC-Severe-cDC_1|Severe / Compartment, Disease Groups and Clusters

WNT4 PHF2 AHNAK IL6R

5.60e-058111446d1e524f000b71c935359afc801a1d31f218fec8
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_ALM_Oprk1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TYRO3 NHSL1 BMP3 DCLK3 ROBO3

6.09e-0516211452d28306c6125b31f11ea6d911a167b93a74907c5
ToppCellAdult-Mesenchymal-chondrocyte-D231|Adult / Lineage, Cell type, age group and donor

GTSE1 PLEKHA4 COL18A1 THBS2 ROBO3

6.45e-0516411452ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

TRIL COL18A1 HMCN2 SMO ROBO3

7.03e-051671145c4e321bb87512ea839f324c92c0f1afea891483f
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CPAMD8 PAPLN NHSL1 NFATC4 SMO

7.03e-0516711455c0ede7783403f1c8004cf8c45785687e89046c6
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

ERICH3 GTSE1 ZNF764 SMO INAVA

7.64e-051701145aabe993c9f337b1caaeb0e64626a3920579c41b7
ToppCell390C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZNF135 TNS2 JAG2 COL18A1 SAA2

7.86e-05171114570963f79711fe6088d6d01b29206b17ab89e5e73
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PGLYRP4 WNT4 SAA1 SAA2 MOCOS

8.08e-0517211455401ac7739f95fb8681cfb4747ab6e447a3c2ae8
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPLN NHSL1 NFATC4 AHNAK LRP4

8.08e-05172114555fba5ce0ead1114e1a76f67ad68432c6bac90e5
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PGLYRP4 WNT4 SAA1 SAA2 MOCOS

8.08e-051721145b3da7f488d191214d7bb74fbac189fe8c29ee6cd
ToppCellfacs-Skin-nan-24m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPHK2 ABCA12 LSR LRP4 IL6R

8.08e-0517211455ca89af7406e7e1a055dd60d6f89615f69e62324
ToppCellEndothelial-Endothelial-G|Endothelial / shred on cell class and cell subclass (v4)

PLEKHA4 TRIL COL18A1 IGF1 MZF1

8.08e-051721145644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PGLYRP4 WNT4 SAA1 SAA2 MOCOS

8.08e-05172114574dd4a7acb2cf857fed20219e4d7dc1adfbaa398
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERICH3 DNAH7 SAA1 SAA2 NUTM2B

8.30e-051731145c3762655caa79ac4879876f470d32578a3c93b01
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF15 NCCRP1 IGF1 LRP4 ARHGEF26

8.53e-051741145165e14cad57e90aa247dcecfaa3c2e8ff2a470ad
ToppCellwk_15-18-Epithelial-Distal_epithelial-type_I_pneumocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

HSPG2 CPAMD8 COX6A2 INAVA AGAP3

8.53e-0517411452cd6638b361ca05ab83d09ce657194aed97873b7
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RNF43 BMP3 CELSR1 ZNRF3 USP54

8.53e-051741145d0e3d15731de6c19c232e3aa492c39d8151cf4ed
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF15 NCCRP1 IGF1 LRP4 ARHGEF26

8.53e-0517411454289dfc7613db4bb3d706b9b65d06e84c0c53558
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NCCRP1 BMP3 COL18A1 GARRE1 IL6R

8.76e-051751145f5451c29c487b998778e50349b3d774d5e20fd28
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

HSPG2 CPAMD8 ECE1 JAG2 HMCN2

9.00e-05176114552af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PGLYRP4 SAA1 SAA2 CELSR1 CRYM

9.24e-051771145779ba86f53650772755b52460be03f18bb204e55
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PGLYRP4 SAA1 SAA2 CELSR1 CRYM

9.24e-0517711450f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

CPAMD8 TYRO3 CELSR1 CRYM PALM3

9.49e-05178114535a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAA1 SAA2 NFATC4 ZBTB10 SMO

9.75e-051791145f99500c4a590e5152ded5862690f7fa614d64a80
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

HSPG2 CPAMD8 ECE1 JAG2 SULF2

9.75e-0517911451ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAA1 SAA2 NFATC4 ZBTB10 SMO

9.75e-0517911457d61466181ab73088de3ec8a129d7cfa8cac7ecc
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAA1 SAA2 NFATC4 ZBTB10 SMO

9.75e-0517911456c98ce32cb55cf9cee557449e41b23bdb22f5efd
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CATSPERZ PAPLN THBS2 LRP4 ARHGEF26

1.03e-041811145b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSPG2 WWP1 LSR AHNAK ARHGEF26

1.05e-041821145573771130247e869e4e58f22d4a1cb31989635cf
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECE1 JAG2 LSR AHNAK GARRE1

1.05e-041821145e6a734fb29105093d4cbfc3d0619a825b66da034
ToppCellfacs-Pancreas-Exocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL18A1 CELSR1 IGF1 AHNAK ARHGEF26

1.05e-04182114545faefd7cbeac84d2c58650530b902af6ce921f8
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSPG2 WWP1 LSR AHNAK ARHGEF26

1.05e-0418211456cfaa2b3b3974c13b01c943f4adb70768dcc35e4
DrugAa1

FCHSD2 SAA2 KIR2DL4 KIR2DS3 KIR2DS5 KIR3DL1

4.43e-06831176CID009549188
DrugHydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; PC3; HT_HG-U133A

PAPPA2 RIBC2 WDR33 C15orf39 TNS2 ECE1 RNF43 SMO

8.00e-0619611783724_DN
Diseasefamilial adenomatous polyposis 1 (implicated_via_orthology)

APC2 APC

1.38e-0521102DOID:0080409 (implicated_via_orthology)
DiseaseSyndactyly Cenani Lenz type

APC LRP4

1.38e-0521102C1859309
DiseaseBenign tumor of pancreas

APC RNF43 BRCA1

1.40e-05131103C0347284
Diseasealkaline phosphatase measurement

HSPG2 GPATCH1 COX6A1 KLF15 PAPLN WNT4 ECE1 ARSG MRPL4 ZNRF3 NFATC4 AHNAK RP1L1 IL6R

2.54e-05101511014EFO_0004533
DiseasePancreatic carcinoma

APC RNF43 BRCA1

4.68e-05191103C0235974
Diseasestomach carcinoma (is_marker_for)

RNF43 KMT2C BRCA1

9.64e-05241103DOID:5517 (is_marker_for)
DiseaseEndometrial Stromal Sarcoma

NUTM2A NUTM2B

1.37e-0451102C0206630
Diseasestomach cancer (is_implicated_in)

APC KMT2C BRCA1 IL6R

1.55e-04721104DOID:10534 (is_implicated_in)
Diseaseneuroimaging measurement

COX6A1 APC JAG2 NHSL1 COL18A1 CELSR1 SULF2 BRCA1 ZNRF3 SSH2 ROBO3 SLC4A9 AGAP3

1.77e-04106911013EFO_0004346
DiseaseClear cell sarcoma of kidney

NUTM2E NUTM2B

2.05e-0461102C0334488
Diseaseserum amyloid A protein measurement

SAA1 SAA2

2.05e-0461102EFO_0004728
DiseasePolysyndactyly

JAG2 LRP4

2.86e-0471102C0265553
DiseaseInflammatory Bowel Diseases

APC2 APC INAVA

3.02e-04351103C0021390
Diseasemitochondrial encephalomyopathy (implicated_via_orthology)

COX6A1 COX6A2

3.80e-0481102DOID:890 (implicated_via_orthology)
DiseaseSyndactyly

JAG2 LRP4

3.80e-0481102C0039075
DiseaseAdenocarcinoma of large intestine

APC RNF43 ZNRF3 DCLK3

4.67e-04961104C1319315
DiseaseLiver Diseases, Parasitic

RNF43 KMT2C

4.87e-0491102C0023897
DiseasePancreatic Neoplasm

APC RNF43 BRCA1 ZNRF3

5.44e-041001104C0030297
DiseaseMalignant neoplasm of pancreas

APC RNF43 BRCA1 ZNRF3

5.87e-041021104C0346647
DiseaseRetinal Detachment

CPAMD8 COL18A1

7.41e-04111102C0035305
Diseasepancreatic cancer (is_implicated_in)

APC IGF1 BRCA1 SMO

8.33e-041121104DOID:1793 (is_implicated_in)
Diseaseuterine fibroid

POGLUT3 WNT4 IGF1 SPINDOC REV1

9.16e-041991105EFO_0000731
DiseaseGraves' disease (is_marker_for)

IGF1 IL6R

1.40e-03151102DOID:12361 (is_marker_for)
Diseaseanemia (implicated_via_orthology)

APC SLC4A9

1.40e-03151102DOID:2355 (implicated_via_orthology)
Diseasecolon cancer (is_marker_for)

RNF43 BRCA1 SMO

1.41e-03591103DOID:219 (is_marker_for)
DiseaseIntellectual Disability

APC2 APC COL18A1 KMT2C BRCA1 PUS7 MAN1B1

1.46e-034471107C3714756
Diseasecortical surface area measurement

CPAMD8 APC WNT4 DNAH7 JAG2 NHSL1 CELSR1 IGF1 SULF2 RP1L1 SSH2 QARS1 AGAP3

1.51e-03134511013EFO_0010736
Diseasecytochrome-c oxidase deficiency disease (implicated_via_orthology)

COX6A1 COX6A2

1.81e-03171102DOID:3762 (implicated_via_orthology)
Diseasestomach cancer (is_marker_for)

ADGRB1 RNF43 BRCA1 SMO

2.00e-031421104DOID:10534 (is_marker_for)
Diseaseserum amyloid A-1 protein measurement

SAA1 SAA2

2.03e-03181102EFO_0008282
DiseaseFemale Urogenital Diseases

WNT4 IGF1

2.03e-03181102C1720887
Diseasecarotid artery disease (is_marker_for)

HSPG2 IGF1

2.26e-03191102DOID:3407 (is_marker_for)
Diseasecardiomyopathy (implicated_via_orthology)

SPHK2 KLF15 COL18A1

2.40e-03711103DOID:0050700 (implicated_via_orthology)
Diseasecitrulline measurement

HMCN2 RP1L1

2.50e-03201102EFO_0009777
Diseasecortical thickness

HSPG2 CPAMD8 ECE1 JAG2 NHSL1 COL18A1 CELSR1 SULF2 LRP4 SSH2 AGAP3

2.97e-03111311011EFO_0004840
Diseasecholangiocarcinoma (is_implicated_in)

APC RNF43

3.03e-03221102DOID:4947 (is_implicated_in)
DiseaseHuntington's disease (is_implicated_in)

IGF1 IL6R

3.31e-03231102DOID:12858 (is_implicated_in)
DiseaseIntrahepatic Cholangiocarcinoma

RNF43 KMT2C

3.60e-03241102C0345905
DiseaseExtrahepatic Cholangiocarcinoma

RNF43 KMT2C

3.60e-03241102C3805278
Diseasemalaria (is_implicated_in)

KIR3DL1 KIR3DS1

3.60e-03241102DOID:12365 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
GTTHKNPKAGQVWRP

C2orf16

1966

Q68DN1
SSAWAGPRPEGLHQR

AGAP3

481

Q96P47
GRNISKTRGWHSPGR

CATSPERZ

56

Q9NTU4
AGAVHEAPLRAWKPT

ERICH3

801

Q5RHP9
TGTRPCWGSTHPRKA

SLC4A9

186

Q96Q91
GHRNFPTGTVPKWDS

BMP3

261

P12645
VPGAPAARWKRHIVR

ATG16L2

6

Q8NAA4
PNKRPWESLRKAHGT

ADGRB1

1526

O14514
RSLRTKIWAPGPHNS

ABCA12

996

Q86UK0
GHKRSTSEGAWPQLP

GSDMD

246

P57764
SHRAPTLVWRPGGEL

C16orf54

66

Q6UWD8
LHRKGDRSPEPGQTW

AHNAK

86

Q09666
PAKQTTWEGGHRVPA

ARSG

331

Q96EG1
ARWITALGHSSGKPP

ARHGEF26

771

Q96DR7
PKVPSGVSDGRWHSV

CELSR1

1516

Q9NYQ6
VGGQPSPHIRITWRS

C1orf147

211

Q96MC9
WVKPGAHINAVGASR

CRYM

216

Q14894
AQVTWHKRGGSLPAR

HSPG2

2181

P98160
AQVTWHKRGGSLPAR

HSPG2

2466

P98160
AQVTWHKRGGNLPAR

HSPG2

2856

P98160
PKPQVTWSKVGGHLR

HSPG2

3516

P98160
QHKPSGRPSWRRQGH

PALM3

106

A6NDB9
LSAWPSAVVPRGGHV

KIR2DL5A

31

Q8N109
RRPDQPGKGSFWALH

FOXB2

76

Q5VYV0
SPGRPRSKQGAWSTH

KMT2C

836

Q8NEZ4
FLPKGWEVRHAPNGR

NEDD4

841

P46934
ALIKQTGRHQPTGPW

NFXL1

601

Q6ZNB6
GHPGNSPWTVSLRNR

MST1L

491

Q2TV78
QVTWRKGPSSEPLHG

HMCN2

1281

Q8NDA2
RPAHWASGPKVDNRA

JAG2

1211

Q9Y219
PVDASKFPWRGGQHR

CELF2-AS1

96

Q8N7Q2
EGWKGDSHRSSPRNP

DCLK3

196

Q9C098
RGPPGRWVQVSHVFR

NCCRP1

221

Q6ZVX7
LSAWPSAVVPRGGHV

KIR2DL5B

31

Q8NHK3
LSAWPSAVVPRGGHV

KIR3DL1

31

P43629
RHAVKGDPQSPGRHW

NHSL1

461

Q5SYE7
QHRGPDKSRKPSRWD

GPATCH1

671

Q9BRR8
GPNHAADPIITRWKR

NUDT9

166

Q9BW91
PGVVPRSVWGARETH

PGLYRP4

211

Q96LB8
PQKSVWHGSDPNGRR

COL18A1

1686

P39060
LQGAWPHEGFRRKPS

KIR2DS3

16

Q14952
PIWQNKPHGAARSVV

MTFR1L

11

Q9H019
SGRLHPVSTPGKWFV

MOCOS

221

Q96EN8
HSSPKQRPRGWFTSG

KIAA1191

181

Q96A73
RVHSVAGPSQWLGKP

OXA1L

21

Q15070
HLRIRTKPFPWGDGN

COX6A1

76

P12074
SSFGPHRVVPDRWKG

RIBC2

266

Q9H4K1
LPAGPVGASSWQAKR

GTSE1

366

Q9NYZ3
GHPRPQIRWTKTAGS

MDGA2

66

Q7Z553
DVNIGTGVAHPPRWT

MAN1B1

376

Q9UKM7
RRPDQPGKGSFWALH

FOXB1

76

Q99853
LQGAWPHEGFRRKPS

KIR2DS5

16

Q14953
WAQQGTTPGTPKLRH

MOGS

121

Q13724
WPSAVVPQGGHVTLR

KIR2DL4

36

Q99706
WLGAKVRRPRASPQH

PAPPA2

51

Q9BXP8
PGLARSQHNRWAGSK

BRCA1

311

P38398
AHGHKQVPRSLWGRP

FAM189B

606

P81408
ISPGARKQAWLPADH

APC2

1021

O95996
VLRKPAAGSHPSRWA

IL6R

61

P08887
RIRTKPYPWGDGNHT

COX6A2

66

Q02221
WGQTPAPQRHSGRVV

CPAMD8

1836

Q8IZJ3
RAPGKWVHGSSQQPA

GARRE1

751

O15063
TLPSDQPKEHWIGRG

DNAH7

4001

Q8WXX0
ATHPGAGGRRSKWDQ

KHDC4

6

Q7Z7F0
GRITINGESPKHRSW

KLHDC1

236

Q8N7A1
GPWRRAAAPVKGEHF

KLF15

106

Q9UIH9
SQRRKGWPKTHPGGE

IGF1

146

P05019
GGWIKANPVPDGHSR

ECE1

131

P42892
RWARPPAVTSNGTLH

FCHSD2

421

O94868
KLRVVGGHPGNSPWT

MST1

481

P26927
TWQGLRRPPSVLGHA

HELZ2

2446

Q9BYK8
RASGPKARPSAGGHW

GPRIN2

76

O60269
PKTHRHRGAWVPAGS

INAVA

486

Q3KP66
LRWAHPPSKAQLRGT

PKD1L1

2256

Q8TDX9
RNGSGKGRSVHPSWP

LSR

11

Q86X29
GRKASPTRTHWVPQA

PCARE

991

A6NGG8
KWGPQGTHQFPSAER

NUTM2A

791

Q8IVF1
KWGPQGTHQSPSAER

NUTM2B

791

A6NNL0
KWGPQGTHQSPSAER

NUTM2E

791

B1AL46
RGEELKGHNTLPSPW

QARS1

361

P47897
RTWHKHGPGQAPDVK

PHF2

66

O75151
KPWPQKGTGRARHGS

MRPL4

126

Q9BYD3
NKWGRSGRDPNHFRP

SAA2

101

P0DJI9
PSPLAWSKARIGGHS

NFATC4

381

Q14934
RVAPRPRGLHSWQKA

RNF113B

61

Q8IZP6
PVVGHSGAQKWLRSS

PLEKHA4

636

Q9H4M7
PSHLRGKGTAQAWTP

ODAD3

36

A5D8V7
LSAWPSAVVPRGGHV

KIR3DS1

31

Q14943
ALANPRKHSWPKSRG

PUS7

241

Q96PZ0
RFQWHGRKPGPETGV

RNF43

561

Q68DV7
DWSRHPQGTKRVGAG

SPINDOC

341

Q9BUA3
GRPKAAAGKWQTLHP

IQANK1

6

A8MXQ7
AAGKWQTLHPGPKTR

IQANK1

11

A8MXQ7
NEWGRSGKDPNHFRP

SAA1

101

P0DJI8
HSSVQAGGWRKLPPN

APC

2496

P25054
NGLALPTWGHKSSRP

C15orf39

1016

Q6ZRI6
GDWPLEHRKVNGTPS

POGLUT3

241

Q7Z4H8
APRNPAPHGVSWVKG

RINL

201

Q6ZS11
FVQGLSKPGRPHQWV

RNF213

4291

Q63HN8
SRSHGVRESPKKWQP

TEX13D

636

A0A0J9YY54
TPERQSPHTWGTRGK

ZNF135

181

P52742
SPHTWGTRGKREKPD

ZNF135

186

P52742
GSWGHGPRSTLVRAK

SPHK2

21

Q9NRA0
HPGAKWYPGSVRRAT

SSH2

856

Q76I76
GKWNGLHTPVSVQSR

REV1

911

Q9UBZ9
GSWGPKTKPSVIHSR

RP1L1

251

Q8IWN7
HRTGAAVQRKPWPSG

PAPLN

841

O95428
QWASTRGGHKERPTV

TINF2

271

Q9BSI4
RGHPEPSVSWRKDGA

ROBO3

191

Q96MS0
SPAGDPWQRATKHRL

TRIL

541

Q7L0X0
EAWRHPSGPARTQLG

TUG1

116

A0A6I8PU40
GKEPWALQGERPRHS

ZNF585B

81

Q52M93
SAPAPVAWAHGRRQG

SMO

751

Q99835
PGAAPDLRRTWKGGH

ZNRF3

691

Q9ULT6
PRNGTVTGKWRGSHV

TMEM219

71

Q86XT9
WRAVPPFRQVGHALK

WNT4

221

P56705
GRPETSVWPLRHFNG

ZBTB10

141

Q96DT7
SVWPLRHFNGRGPAT

ZBTB10

146

Q96DT7
GNTPGQVRTLWHDPR

THBS2

1086

P35442
RKRPWHDGPGTSEHR

WDR33

1231

Q9C0J8
LPSGWEQRKDPHGRT

WWP1

351

Q9H0M0
AAQPRNLTKRHWPGA

SULF2

556

Q8IWU5
RAGQQGPPHSRTSWV

TYRO3

416

Q06418
GWASEAGKPLLHPVR

TNS2

716

Q63HR2
YGWEQLSKAPHRGRP

ZNF764

146

Q96H86
KRWGPARPGSHLLEQ

USP54

636

Q70EL1
TPERRGSLPDTGWKH

LRP4

1881

O75096
KTGPEGPSWREHPRA

MZF1

231

P28698