Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionzinc ion sequestering activity

S100A7 S100A7A

1.31e-044942GO:0140486
GeneOntologyBiologicalProcesscytidine to uridine editing

APOBEC3G RBM47 APOBEC3F

1.90e-0512933GO:0016554
GeneOntologyCellularComponentapolipoprotein B mRNA editing enzyme complex

APOBEC3G RBM47 APOBEC3F

8.47e-075933GO:0030895
GeneOntologyCellularComponentmRNA editing complex

APOBEC3G RBM47 APOBEC3F

2.95e-067933GO:0045293
GeneOntologyCellularComponentphotoreceptor ribbon synapse

CDH23 DNM1 RIMS2

6.63e-0518933GO:0098684
GeneOntologyCellularComponentribbon synapse

CDH23 DNM1 RIMS2

3.85e-0432933GO:0097470
GeneOntologyCellularComponentphotoreceptor inner segment

KIFAP3 USH1G CDH23 DNM1

4.07e-0478934GO:0001917
GeneOntologyCellularComponentinner dynein arm

DNAH6 DNAH1

8.61e-0410932GO:0036156
DomainS100A7

S100A7 S100A7A

2.45e-052932IPR028477
DomainCK1gamma_C

CSNK1G2 CSNK1G1

7.33e-053932PF12605
DomainCasein_kinase-1_gamma_C

CSNK1G2 CSNK1G1

7.33e-053932IPR022247
DomainDBINO

SMARCA1 INO80

7.33e-053932PF13892
DomainDBINO

SMARCA1 INO80

7.33e-053932IPR020838
DomainTPR-like_helical_dom

UTP6 RAPSN POLR1A UNC45A FEM1C TTC4 GTF3C3

1.64e-04233937IPR011990
DomainHnRNP_R/Q_splicing_fac

RBM46 RBM47

2.43e-045932IPR006535
DomainARM-type_fold

DOCK3 KIFAP3 DOCK9 RRP12 AP1G2 UNC45A HUWE1 USP9Y

2.89e-04339938IPR016024
DomainS100_CABP

S100A7 S100A7A S100Z

3.21e-0427933PS00303
DomainS_100

S100A7 S100A7A S100Z

3.21e-0427933PF01023
DomainS100_Ca-bd_sub

S100A7 S100A7A S100Z

3.58e-0428933IPR013787
DomainS100/CaBP-9k_CS

S100A7 S100A7A S100Z

3.58e-0428933IPR001751
DomainS_100

S100A7 S100A7A S100Z

3.58e-0428933SM01394
Domain-

UTP6 RAPSN UNC45A FEM1C TTC4 GTF3C3

5.90e-042079361.25.40.10
Domain-

DPYSL3 AMDHD1

6.74e-0489322.30.40.10
DomainTPR_1

RAPSN UNC45A TTC4 GTF3C3

1.06e-0390934PF00515
DomainTPR_1

RAPSN UNC45A TTC4 GTF3C3

1.06e-0390934IPR001440
DomainAmidohydro_1

DPYSL3 AMDHD1

1.08e-0310932PF01979
DomainMetal-dep_hydrolase_composite

DPYSL3 AMDHD1

1.08e-0310932IPR011059
DomainElongated_TPR_rpt_dom

UNC45A TTC4

1.31e-0311932IPR023114
DomainDOCK_C

DOCK3 DOCK9

1.31e-0311932IPR010703
DomainAmidohydro-rel

DPYSL3 AMDHD1

1.31e-0311932IPR006680
DomainDHR-1_domain

DOCK3 DOCK9

1.31e-0311932IPR027007
DomainDHR_2

DOCK3 DOCK9

1.31e-0311932PS51651
DomainDHR_1

DOCK3 DOCK9

1.31e-0311932PS51650
DomainDOCK-C2

DOCK3 DOCK9

1.31e-0311932PF14429
DomainDHR-2

DOCK3 DOCK9

1.31e-0311932IPR027357
DomainDHR-2

DOCK3 DOCK9

1.31e-0311932PF06920
DomainDOCK

DOCK3 DOCK9

1.31e-0311932IPR026791
DomainTPR_REGION

RAPSN UNC45A FEM1C TTC4 GTF3C3

1.41e-03165935PS50293
DomainTPR

RAPSN UNC45A FEM1C TTC4 GTF3C3

1.41e-03165935PS50005
DomainAPOBEC_N

APOBEC3G APOBEC3F

1.57e-0312932PF08210
DomainAPOBEC_N

APOBEC3G APOBEC3F

1.57e-0312932IPR013158
DomainFERM-adjacent

EPB41L1 FARP2

1.85e-0313932IPR014847
DomainFA

EPB41L1 FARP2

1.85e-0313932SM01195
DomainFA

EPB41L1 FARP2

1.85e-0313932PF08736
Domain-

ECI2 EPB41L1 FARP2

1.87e-03499331.20.80.10
DomainFERM/acyl-CoA-bd_prot_3-hlx

ECI2 EPB41L1 FARP2

1.98e-0350933IPR014352
DomainDynein_heavy_chain_D4_dom

DNAH6 DNAH1

2.15e-0314932IPR024317
DomainDynein_HC_stalk

DNAH6 DNAH1

2.15e-0314932IPR024743
DomainDynein_heavy_dom-2

DNAH6 DNAH1

2.15e-0314932IPR013602
DomainDHC_N2

DNAH6 DNAH1

2.15e-0314932PF08393
DomainMT

DNAH6 DNAH1

2.15e-0314932PF12777
DomainAAA_8

DNAH6 DNAH1

2.15e-0314932PF12780
DomainAPOBEC/CMP_deaminase_Zn-bd

APOBEC3G APOBEC3F

2.15e-0314932IPR016192
DomainATPase_dyneun-rel_AAA

DNAH6 DNAH1

2.15e-0314932IPR011704
DomainAAA_5

DNAH6 DNAH1

2.15e-0314932PF07728
DomainARM-like

KIFAP3 RRP12 AP1G2 UNC45A HUWE1 USP9Y

2.30e-03270936IPR011989
DomainDHC_fam

DNAH6 DNAH1

2.47e-0315932IPR026983
DomainDynein_heavy_dom

DNAH6 DNAH1

2.47e-0315932IPR004273
DomainCYT_DCMP_DEAMINASES_2

APOBEC3G APOBEC3F

2.47e-0315932PS51747
DomainDynein_heavy

DNAH6 DNAH1

2.47e-0315932PF03028
DomainCytidine_deaminase-like

APOBEC3G APOBEC3F

3.18e-0317932IPR016193
DomainCYT_DCMP_DEAMINASES_1

APOBEC3G APOBEC3F

3.18e-0317932PS00903
DomainCMP_dCMP_Zn-bd

APOBEC3G APOBEC3F

3.18e-0317932IPR002125
DomainTPR

RAPSN UNC45A TTC4 GTF3C3

3.95e-03129934SM00028
DomainUSP_CS

USP6 USP17L10 USP9Y

4.36e-0366933IPR018200
DomainTPR_repeat

RAPSN UNC45A TTC4 GTF3C3

4.40e-03133934IPR019734
DomainEz/rad/moesin-like

EPB41L1 FARP2

4.84e-0321932IPR000798
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

UTP6 S100A7 MYH10 WASHC4 POLR1A RRP12 HSPH1 SMARCA1 AP1G2 NUP93 UNC45A HUWE1 PAPSS2 ELP3 SERPINH1 YME1L1 GTF3C3 ARCN1

2.03e-081353941829467282
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

INTS10 UIMC1 LMAN2L MAN2A1 POLR1A AKAP17A CSNK1G2 PPFIBP1 RRP12 HSPH1 HELZ2 WDR55 INO80 UNC45A SERPINH1 YME1L1 EPB41L1 FARP2

9.32e-081497941831527615
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DOCK3 CHAF1B PTPRA WASHC4 AKAP17A PPFIBP1 ADAM9 HSPH1 LMO3 HUWE1 DNM1 USP9Y SULT4A1 YME1L1 ARCN1 SCAI

3.35e-071285941635914814
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

MYH10 POLR1A SMARCA1 NUP93 UNC45A PAPSS2 ELP3 SERPINH1 YME1L1 GTF3C3 ARCN1

7.08e-07601941133658012
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

S100A7 PTPRA CSNK1G2 PPFIBP1 ADAM9 DOCK9 SLCO4A1 TTC4 EPB41L1 FARP2

3.35e-06569941030639242
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

MED18 MYH10 NMNAT1 AKAP17A HSPH1 CSNK1G1 HELZ2 SMARCA1 WDR55 NUP93 UNC45A RBM47 GTF3C3 ARCN1 APOBEC3F

3.99e-061371941536244648
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

UTP6 MYH10 NMNAT1 PPFIBP1 RRP12 HSPH1 HELZ2 SMARCA1 NUP93 UNC45A SERPINH1 ITGB4 GTF3C3 ARCN1

7.09e-061257941436526897
Pubmed

Death and the retrovirus.

APOBEC3G APOBEC3F

7.23e-06294214557052
Pubmed

Long-term restriction by APOBEC3F selects human immunodeficiency virus type 1 variants with restored Vif function.

APOBEC3G APOBEC3F

7.23e-06294220686027
Pubmed

Cytidine deaminases APOBEC3G and APOBEC3F interact with human immunodeficiency virus type 1 integrase and inhibit proviral DNA formation.

APOBEC3G APOBEC3F

7.23e-06294217428847
Pubmed

Contribution of APOBEC3G/F activity to the development of low-abundance drug-resistant human immunodeficiency virus type 1 variants.

APOBEC3G APOBEC3F

7.23e-06294226482266
Pubmed

High level of APOBEC3F/3G editing in HIV-2 DNA vif and pol sequences from antiretroviral-naive patients.

APOBEC3G APOBEC3F

7.23e-06294225985400
Pubmed

APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G.

APOBEC3G APOBEC3F

7.23e-06294217121840
Pubmed

Quantification of deaminase activity-dependent and -independent restriction of HIV-1 replication mediated by APOBEC3F and APOBEC3G through experimental-mathematical investigation.

APOBEC3G APOBEC3F

7.23e-06294224623435
Pubmed

Status of APOBEC3G/F in cells and progeny virions modulated by Vif determines HIV-1 infectivity.

APOBEC3G APOBEC3F

7.23e-06294219944180
Pubmed

Dispersed sites of HIV Vif-dependent polyubiquitination in the DNA deaminase APOBEC3F.

APOBEC3G APOBEC3F

7.23e-06294223318957
Pubmed

Different interaction between HIV-1 Vif and its cellular target proteins APOBEC3G/APOBEC3F.

APOBEC3G APOBEC3F

7.23e-06294220299747
Pubmed

Identification of two distinct human immunodeficiency virus type 1 Vif determinants critical for interactions with human APOBEC3G and APOBEC3F.

APOBEC3G APOBEC3F

7.23e-06294217522216
Pubmed

Characterization of conserved motifs in HIV-1 Vif required for APOBEC3G and APOBEC3F interaction.

APOBEC3G APOBEC3F

7.23e-06294218619467
Pubmed

E138K and M184I mutations in HIV-1 reverse transcriptase coemerge as a result of APOBEC3 editing in the absence of drug exposure.

APOBEC3G APOBEC3F

7.23e-06294222695298
Pubmed

Remarkable lethal G-to-A mutations in vif-proficient HIV-1 provirus by individual APOBEC3 proteins in humanized mice.

APOBEC3G APOBEC3F

7.23e-06294220610708
Pubmed

Genetic editing of HBV DNA by monodomain human APOBEC3 cytidine deaminases and the recombinant nature of APOBEC3G.

APOBEC3G APOBEC3F

7.23e-06294219169351
Pubmed

Interactions in vivo between the Vif protein of HIV-1 and the precursor (Pr55(GAG)) of the virion nucleocapsid proteins.

APOBEC3G APOBEC3F

7.23e-06294219826902
Pubmed

The retroviral hypermutation specificity of APOBEC3F and APOBEC3G is governed by the C-terminal DNA cytosine deaminase domain.

APOBEC3G APOBEC3F

7.23e-06294215647250
Pubmed

APOBEC3F and APOBEC3G inhibit HIV-1 DNA integration by different mechanisms.

APOBEC3G APOBEC3F

7.23e-06294220219927
Pubmed

Differential requirement for conserved tryptophans in human immunodeficiency virus type 1 Vif for the selective suppression of APOBEC3G and APOBEC3F.

APOBEC3G APOBEC3F

7.23e-06294216501124
Pubmed

Moderate influence of human APOBEC3F on HIV-1 replication in primary lymphocytes.

APOBEC3G APOBEC3F

7.23e-06294220592068
Pubmed

HIV-1 Vif: counteracting innate antiretroviral defenses.

APOBEC3G APOBEC3F

7.23e-06294214565218
Pubmed

Comparison of cellular ribonucleoprotein complexes associated with the APOBEC3F and APOBEC3G antiviral proteins.

APOBEC3G APOBEC3F

7.23e-06294218367521
Pubmed

Inhibition of initiation of reverse transcription in HIV-1 by human APOBEC3F.

APOBEC3G APOBEC3F

7.23e-06294217459442
Pubmed

Antiviral roles of APOBEC proteins against HIV-1 and suppression by Vif.

APOBEC3G APOBEC3F

7.23e-06294219669862
Pubmed

Promiscuous RNA binding ensures effective encapsidation of APOBEC3 proteins by HIV-1.

APOBEC3G APOBEC3F

7.23e-06294225590131
Pubmed

Identification of a novel WxSLVK motif in the N terminus of human immunodeficiency virus and simian immunodeficiency virus Vif that is critical for APOBEC3G and APOBEC3F neutralization.

APOBEC3G APOBEC3F

7.23e-06294219535447
Pubmed

Comparative analysis of the gene-inactivating potential of retroviral restriction factors APOBEC3F and APOBEC3G.

APOBEC3G APOBEC3F

7.23e-06294226048885
Pubmed

Identification of two APOBEC3F splice variants displaying HIV-1 antiviral activity and contrasting sensitivity to Vif.

APOBEC3G APOBEC3F

7.23e-06294220624919
Pubmed

Differential sensitivity of porcine endogenous retrovirus to APOBEC3-mediated inhibition.

APOBEC3G APOBEC3F

7.23e-06294226016442
Pubmed

The HIV-1 central polypurine tract functions as a second line of defense against APOBEC3G/F.

APOBEC3G APOBEC3F

7.23e-06294220844042
Pubmed

Molecular docking analysis of RN18 and VEC5 in A3G-Vif inhibition.

APOBEC3G APOBEC3F

7.23e-06294225489169
Pubmed

RNA and DNA binding properties of HIV-1 Vif protein: a fluorescence study.

APOBEC3G APOBEC3F

7.23e-06294217609216
Pubmed

Stably expressed APOBEC3F has negligible antiviral activity.

APOBEC3G APOBEC3F

7.23e-06294220702622
Pubmed

Distinct domains within APOBEC3G and APOBEC3F interact with separate regions of human immunodeficiency virus type 1 Vif.

APOBEC3G APOBEC3F

7.23e-06294219036809
Pubmed

Defining APOBEC3 expression patterns in human tissues and hematopoietic cell subsets.

APOBEC3G APOBEC3F

7.23e-06294219587057
Pubmed

T cells target APOBEC3 proteins in human immunodeficiency virus type 1-infected humans and simian immunodeficiency virus-infected Indian rhesus macaques.

APOBEC3G APOBEC3F

7.23e-06294223536679
Pubmed

Unusual substitutions in HIV-1 vif from children infected perinatally without progression to AIDS for more than 8 years without therapy.

APOBEC3G APOBEC3F

7.23e-06294223080486
Pubmed

Heterozygous mutation of Ush1g/Sans in mice causes early-onset progressive hearing loss, which is recovered by reconstituting the strain-specific mutation in Cdh23.

USH1G CDH23

7.23e-06294226936824
Pubmed

Biochemical differentiation of APOBEC3F and APOBEC3G proteins associated with HIV-1 life cycle.

APOBEC3G APOBEC3F

7.23e-06294217142455
Pubmed

A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteins.

APOBEC3G APOBEC3F

7.23e-06294215152192
Pubmed

Tumultuous relationship between the human immunodeficiency virus type 1 viral infectivity factor (Vif) and the human APOBEC-3G and APOBEC-3F restriction factors.

APOBEC3G APOBEC3F

7.23e-06294219487726
Pubmed

APOBEC deaminases as cellular antiviral factors: a novel natural host defense mechanism.

APOBEC3G APOBEC3F

7.23e-06294216641889
Pubmed

Comparison of G-to-A mutation frequencies induced by APOBEC3 proteins in H9 cells and peripheral blood mononuclear cells in the context of impaired processivities of drug-resistant human immunodeficiency virus type 1 reverse transcriptase variants.

APOBEC3G APOBEC3F

7.23e-06294218448538
Pubmed

Human APOBEC3F incorporation into human immunodeficiency virus type 1 particles.

APOBEC3G APOBEC3F

7.23e-06294225038404
Pubmed

Expression of APOBEC3G/3F and G-to-A hypermutation levels in HIV-1-infected children with different profiles of disease progression.

APOBEC3G APOBEC3F

7.23e-06294221897871
Pubmed

Structural determinants of HIV-1 Vif susceptibility and DNA binding in APOBEC3F.

APOBEC3G APOBEC3F

7.23e-06294224185281
Pubmed

Identification of 81LGxGxxIxW89 and 171EDRW174 domains from human immunodeficiency virus type 1 Vif that regulate APOBEC3G and APOBEC3F neutralizing activity.

APOBEC3G APOBEC3F

7.23e-06294220335268
Pubmed

APOBEC3G and APOBEC3F require an endogenous cofactor to block HIV-1 replication.

APOBEC3G APOBEC3F

7.23e-06294218604271
Pubmed

Identification of amino acid residues in HIV-1 Vif critical for binding and exclusion of APOBEC3G/F.

APOBEC3G APOBEC3F

7.23e-06294218603011
Pubmed

Positioning of APOBEC3G/F mutational hotspots in the human immunodeficiency virus genome favors reduced recognition by CD8+ T cells.

APOBEC3G APOBEC3F

7.23e-06294224722422
Pubmed

Population level analysis of human immunodeficiency virus type 1 hypermutation and its relationship with APOBEC3G and vif genetic variation.

APOBEC3G APOBEC3F

7.23e-06294216940537
Pubmed

Inhibition of LINE-1 and Alu retrotransposition by exosomes encapsidating APOBEC3G and APOBEC3F.

APOBEC3G APOBEC3F

7.23e-06294220153011
Pubmed

Mechanism of Enhanced HIV Restriction by Virion Coencapsidated Cytidine Deaminases APOBEC3F and APOBEC3G.

APOBEC3G APOBEC3F

7.23e-06294227881650
Pubmed

APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection.

APOBEC3G APOBEC3F

7.23e-06294217145955
Pubmed

Repression of porcine endogenous retrovirus infection by human APOBEC3 proteins.

APOBEC3G APOBEC3F

7.23e-06294221396348
Pubmed

Comparative analysis of the antiretroviral activity of APOBEC3G and APOBEC3F from primates.

APOBEC3G APOBEC3F

7.23e-06294216460778
Pubmed

A single amino acid substitution in human APOBEC3G antiretroviral enzyme confers resistance to HIV-1 virion infectivity factor-induced depletion.

APOBEC3G APOBEC3F

7.23e-06294215054139
Pubmed

Inhibition of hepatitis B virus replication by APOBEC3G.

APOBEC3G APOBEC3F

7.23e-06294215031497
Pubmed

Catalytic activity of APOBEC3F is required for efficient restriction of Vif-deficient human immunodeficiency virus.

APOBEC3G APOBEC3F

7.23e-06294224503066
Pubmed

APOBEC3 proteins and reverse transcription.

APOBEC3G APOBEC3F

7.23e-06294218262674
Pubmed

Different mutagenic potential of HIV-1 restriction factors APOBEC3G and APOBEC3F is determined by distinct single-stranded DNA scanning mechanisms.

APOBEC3G APOBEC3F

7.23e-06294224651717
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

DOCK3 LMAN2L SPHK1 CSNK1G2 DOCK9 RRP12 HELZ2 DIP2C SLCO4A1 AP1G2 INO80 HUWE1 ITGB4

8.72e-061105941335748872
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

UTP6 POLR1A ADAM9 RRP12 HSPH1 NUP93 UNC45A HUWE1 SERPINH1 YME1L1 GTF3C3 ARCN1

9.05e-06942941231073040
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

MYH10 PPP2R2D HSPH1 ECI2 UNC45A HUWE1 SERPINH1 YME1L1 ITGB4 ARCN1

1.03e-05647941026618866
Pubmed

S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature).

S100A7 S100A7A S100Z

1.51e-051894315336958
Pubmed

An update of the S100 nomenclature.

S100A7 S100A7A S100Z

1.80e-051994316938360
Pubmed

The activity spectrum of Vif from multiple HIV-1 subtypes against APOBEC3G, APOBEC3F, and APOBEC3H.

APOBEC3G APOBEC3F

2.16e-05394222013041
Pubmed

Small-molecule inhibition of HIV-1 Vif.

APOBEC3G APOBEC3F

2.16e-05394218806783
Pubmed

Defining HIV-1 Vif residues that interact with CBFβ by site-directed mutagenesis.

APOBEC3G APOBEC3F

2.16e-05394224418540
Pubmed

Enhancing immunity to HIV through APOBEC.

APOBEC3G APOBEC3F

2.16e-05394218846074
Pubmed

APOBEC3DE Antagonizes Hepatitis B Virus Restriction Factors APOBEC3F and APOBEC3G.

APOBEC3G APOBEC3F

2.16e-05394227289067
Pubmed

The mouse S100A15 ortholog parallels genomic organization, structure, gene expression, and protein-processing pattern of the human S100A7/A15 subfamily during epidermal maturation.

S100A7 S100A7A

2.16e-05394216528363
Pubmed

Restriction of retroviral replication by APOBEC3G/F and TRIM5alpha.

APOBEC3G APOBEC3F

2.16e-05394218976920
Pubmed

HIV-1 Vif adaptation to human APOBEC3H haplotypes.

APOBEC3G APOBEC3F

2.16e-05394224139399
Pubmed

Nuclear import of APOBEC3F-labeled HIV-1 preintegration complexes.

APOBEC3G APOBEC3F

2.16e-05394224248339
Pubmed

HIV-1 and HIV-2 Vif interact with human APOBEC3 proteins using completely different determinants.

APOBEC3G APOBEC3F

2.16e-05394224942576
Pubmed

A single amino acid difference in human APOBEC3H variants determines HIV-1 Vif sensitivity.

APOBEC3G APOBEC3F

2.16e-05394219939923
Pubmed

Identification of a critical T(Q/D/E)x5ADx2(I/L) motif from primate lentivirus Vif proteins that regulate APOBEC3G and APOBEC3F neutralizing activity.

APOBEC3G APOBEC3F

2.16e-05394220592083
Pubmed

APOBEC3D and APOBEC3F potently promote HIV-1 diversification and evolution in humanized mouse model.

APOBEC3G APOBEC3F

2.16e-05394225330146
Pubmed

Expression analysis of the mouse S100A7/psoriasin gene in skin inflammation and mammary tumorigenesis.

S100A7 S100A7A

2.16e-05394215717926
Pubmed

Accessories to the crime: recent advances in HIV accessory protein biology.

APOBEC3G APOBEC3F

2.16e-05394219149995
Pubmed

Endogenous origins of HIV-1 G-to-A hypermutation and restriction in the nonpermissive T cell line CEM2n.

APOBEC3G APOBEC3F

2.16e-05394222807680
Pubmed

S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways.

S100A7 S100A7A

2.16e-05394222158945
Pubmed

Mutation rates and intrinsic fidelity of retroviral reverse transcriptases.

APOBEC3G APOBEC3F

2.16e-05394221994586
Pubmed

Initiation of HIV Reverse Transcription.

APOBEC3G APOBEC3F

2.16e-05394221994608
Pubmed

Identification of a novel HIV-1 inhibitor targeting Vif-dependent degradation of human APOBEC3G protein.

APOBEC3G APOBEC3F

2.16e-05394225724652
Pubmed

APOBEC-mediated viral restriction: not simply editing?

APOBEC3G APOBEC3F

2.16e-05394217303427
Pubmed

An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions.

MYH10 PTPRA

2.16e-05394225631816
Pubmed

Comparative analysis of the physical properties of murine and human S100A7: Insight into why zinc piracy is mediated by human but not murine S100A7.

S100A7 S100A7A

2.16e-05394237769710
Pubmed

Natural resistance to HIV infection: The Vif-APOBEC interaction.

APOBEC3G APOBEC3F

2.16e-05394217067930
Pubmed

HELZ2 promotes K63-linked polyubiquitination of c-Myc to induce retinoblastoma tumorigenesis.

HELZ2 HUWE1

2.16e-05394234761308
Pubmed

Structural Insights into HIV-1 Vif-APOBEC3F Interaction.

APOBEC3G APOBEC3F

2.16e-05394226537685
Pubmed

Differential Activity of APOBEC3F, APOBEC3G, and APOBEC3H in the Restriction of HIV-2.

APOBEC3G APOBEC3F

2.16e-05394234774569
Cytoband4p14

FAM114A1 RBM47 KLB

9.01e-05429434p14
CytobandEnsembl 112 genes in cytogenetic band chr4p14

FAM114A1 RBM47 KLB

3.62e-0467943chr4p14
GeneFamilyS100 calcium binding proteins|EF-hand domain containing

S100A7 S100A7A S100Z

6.45e-0521683459
GeneFamilyApolipoprotein B mRNA editing enzyme catalytic subunits

APOBEC3G APOBEC3F

8.98e-0412682406
GeneFamilyDyneins, axonemal

DNAH6 DNAH1

1.83e-0317682536
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_capillary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DPYSL3 PPFIBP1 DOCK9 SLCO4A1 FNBP1L SERPINH1 EPAS1

2.28e-072009472d962c9d63e9e5f1a06870e383609672e7b1738c
ToppCellfacs-Marrow-T-cells-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDH23 HUWE1 DNM1 RBM47 ARCN1 FARP2

2.37e-0618194657f0cc749ae8b6a3d77e2af31f9a6e4739c57049
ToppCellfacs-Marrow-T-cells-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDH23 HUWE1 DNM1 RBM47 ARCN1 FARP2

2.37e-06181946d01b35cc2fc57991a35be6a06cb7351fbabd9a11
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN1 FAM114A1 DPYSL3 ADAM9 DNM1 SERPINH1

3.33e-06192946beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCellNS-critical-d_0-4-Lymphoid-NK|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FBLN1 SMARCA1 WDR55 NUP93 USP9Y SERPINH1

3.43e-061939461b29525c5936d1b779253b8c20f059fa091c6127
ToppCellfacs-Bladder-nan-3m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN1 FAM114A1 DPYSL3 MYH10 DNM1 SERPINH1

3.64e-06195946223f5f07dc28fa13a09bb589884c58043c7928c7
ToppCellASK452-Endothelial-Endothelium|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

DPYSL3 PPFIBP1 DOCK9 SLCO4A1 PAPSS2 EPAS1

3.97e-06198946e282769f5fa1765bcce79a0ed9d761bf2e14b012
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

FBLN1 DPYSL3 MYH10 SMARCA1 DIP2C SERPINH1

4.09e-061999465b9d355795dd03a22f0961dfd143425c367a4654
ToppCellASK452-Endothelial|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

DPYSL3 PPFIBP1 DOCK9 SLCO4A1 PAPSS2 EPAS1

4.09e-061999460bc97a9a78aaafd1554ae6a61356ed9ea4983fa5
ToppCellmedial-2-Endothelial-Capillary_Intermediate_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PPFIBP1 DOCK9 SLCO4A1 FNBP1L PAPSS2 EPAS1

4.21e-06200946a8adf5902540f6bb15b72efbb9c389b59d67e001
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DPYSL3 PPFIBP1 DOCK9 SLCO4A1 FNBP1L EPAS1

4.21e-062009462989325b0e78ab42f362cfb59e34a4fce7f8e869
ToppCellmedial-Endothelial-Capillary_Intermediate_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PPFIBP1 DOCK9 SLCO4A1 FNBP1L PAPSS2 EPAS1

4.21e-062009463ef7b7728615710c691aed8977e2582f19692cf9
ToppCellmedial-Endothelial-Capillary_Intermediate_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PPFIBP1 DOCK9 SLCO4A1 FNBP1L PAPSS2 EPAS1

4.21e-06200946707148e01e961097819a05437a842b7d3bf72b0a
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FBLN1 SPHK1 PIPOX RBM46 RBM47

1.28e-051429456a656d28c9f5dfb03a3a2d908cf2edbe0a5b1206
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FBLN1 SPHK1 PIPOX RBM46 RBM47

1.28e-05142945671ba8869db7a6dc69fd1caf0e561f15a312b170
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FBLN1 SPHK1 PIPOX RBM46 RBM47

1.28e-051429453557084150670fd2e2634fc674f228ab85181b59
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FBLN1 SPHK1 PIPOX RBM46 RBM47

1.28e-05142945a3d1f4b570b75402171e38c5a7c88e2896520c8f
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|343B / Donor, Lineage, Cell class and subclass (all cells)

MED18 APOBEC3G AP1G2 RGS13 APOBEC3F

2.07e-051579450362c04b7b0b5017964b3a73ee678ae53e7238d7
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DOCK3 FBXO31 SMARCA1 WDR55 APOBEC3F

2.71e-051669458d5d09f25e8903d481c2097fed435e69d42ccdb5
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS10 PTPRA POLR1A CSNK1G1 APOBEC3G

3.49e-0517594526bd957498e41a3f1ffa60d3effa27ca8c4ba631
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPHK1 PPFIBP1 DOCK9 SULT4A1 ITGB4

3.68e-05177945227d4f423b00be2e0c5797e2c5275d342e69a0f4
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPHK1 PPFIBP1 DOCK9 SULT4A1 ITGB4

3.68e-0517794566ffa279147961080c104242a08b176e301d80e3
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

HSPH1 AMDHD1 SERPINH1 EPAS1 RGS13

3.68e-0517794552c2ba74a8605260a2623e7d151286e504ac4d19
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPHK1 PPFIBP1 DOCK9 SULT4A1 ITGB4

3.68e-051779450cbf54608d2ba0a0500af142f2029fe5e118c3c2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPHK1 TMEM151B S100Z DNM1 SULT4A1

3.99e-05180945d76349ecef7c5878bf215e946f032264161eb61b
ToppCell368C-Endothelial_cells-Endothelial-E|368C / Donor, Lineage, Cell class and subclass (all cells)

PPFIBP1 DOCK9 SLCO4A1 FNBP1L EPAS1

3.99e-051809458ab16a0b9053bffc07b569a4f9e71749f56dde7e
ToppCell368C-Endothelial_cells-Endothelial-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

PPFIBP1 DOCK9 SLCO4A1 FNBP1L EPAS1

3.99e-05180945394cd465b88429b70eebb2957480dffcbc51cfe7
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM151B SMARCA1 DNM1 SULT4A1 ITGB4

4.10e-051819457af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MED18 PPP2R2D POGK CAPN3 SENP5

4.10e-05181945709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CHAF1B SLCO4A1 RIMS2 PAPSS2 DNAH6

4.20e-05182945a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

USP6 SPHK1 PPFIBP1 RIMS2 APOBEC3F

4.43e-0518494530ca56d64c961127e26122613e35aa2b46fde2df
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4|TCGA-Thryoid / Sample_Type by Project: Shred V9

CHAF1B DOCK9 WDR55 RIMS2 HACD1

4.43e-05184945d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCell(00)_Basal-(4)_1wkpi|(00)_Basal / shred by cell type and Timepoint

SEC14L3 MAN2A1 SERPINH1 ITGB4 EPAS1

4.54e-05185945bf82ba905e5eee1c39a2731702071d3de10a78b8
ToppCellCOVID_vent-Myeloid-Monocytic-SC_&_Eosinophil|COVID_vent / Disease condition, Lineage, Cell class and subclass

DPYSL3 MYH10 PPFIBP1 NTRK1 HACD1

5.03e-051899452157a2d40613f7d5ce2e7dbd266df441e449cdaf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 SLCO4A1 RIMS2 PAPSS2 DNAH6

5.03e-05189945e059be2965cca70ff5576df055d0af1775b76e00
ToppCellCOVID-19-lung-Artery_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK9 HSPH1 SLCO4A1 PAPSS2 EPAS1

5.16e-0519094507b675befcd1d0a9c90cb17b5d22323468325d51
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DPYSL3 PPFIBP1 DOCK9 SLCO4A1 EPAS1

5.16e-051909450e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DPYSL3 PPFIBP1 DOCK9 SLCO4A1 EPAS1

5.16e-051909450a351609a72fd638c84b2435782e312ee6a33aac
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

DPYSL3 PPFIBP1 DOCK9 SLCO4A1 EPAS1

5.29e-05191945f229abf69a1217194f74b0502486907e07dba989
ToppCelldroplet-Lung-30m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DPYSL3 DOCK9 SERPINH1 ITGB4 EPAS1

5.42e-05192945452d54f0aca8657722d7ac61e8422921d08c06b3
ToppCelldroplet-Lung-30m-Endothelial-venous_endothelial-vein_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DPYSL3 DOCK9 SERPINH1 ITGB4 EPAS1

5.42e-051929457ddaca206599603d4d0b2afb73ed2850225d277d
ToppCelldroplet-Lung-30m-Endothelial-venous_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DPYSL3 DOCK9 SERPINH1 ITGB4 EPAS1

5.42e-05192945bf0b996aeedc34a79c71df3379ec9c1aabe06a8c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FBLN1 PAPSS2 SERPINH1 EPAS1 EPB41L1

5.56e-05193945dd4bac8a93a5b9dcf7301f1d7d6e3eb6670f5c68
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FBLN1 PAPSS2 SERPINH1 EPAS1 EPB41L1

5.56e-051939452ddf9b2770a0be9689e01d1a3d19e4a6d42c7a50
ToppCellLV-10._Endothelium_II|LV / Chamber and Cluster_Paper

DOCK9 SLCO4A1 PAPSS2 ITGB4 EPAS1

5.69e-05194945b6cc849fa08599bff9839ef382d190cc964e273e
ToppCelldroplet-Bladder-Unstain-18m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN1 MYH10 SPHK1 HSPH1 SERPINH1

5.69e-05194945ee6b5fb4e993a4c0dc556091b8fefd56bdc70d8f
ToppCellCOPD-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

PPFIBP1 DOCK9 SLCO4A1 FNBP1L EPAS1

5.69e-0519494568705a6eca947c5b42b943d5224a7aef2a744007
ToppCellCOPD-Endothelial-VE_Capillary_B|COPD / Disease state, Lineage and Cell class

PPFIBP1 DOCK9 SLCO4A1 FNBP1L EPAS1

5.69e-0519494518b7f901c12ca4f21f9a1eafd092aefe4d668b6d
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DPYSL3 DOCK9 SLCO4A1 PAPSS2 EPAS1

5.69e-0519494540842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCelldroplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN1 MYH10 SPHK1 HSPH1 SERPINH1

5.83e-05195945841fde528ecb293e07b5e00e499d1e9f0b0dce14
ToppCellmild-B_cell|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ADAMTS10 UIMC1 STAP2 FNBP1L TTC4

5.83e-051959451e5f1967bcc898318f4e970b844b4a944eb168e5
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIFAP3 MYH10 DNM1 RIMS2 SCAI

5.98e-05196945676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellCOVID-19-lung-Capillary_Aerocytes|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPFIBP1 DOCK9 SLCO4A1 PAPSS2 EPAS1

5.98e-0519694549cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCellCOVID-19-lung-Capillary_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPFIBP1 DOCK9 SLCO4A1 PAPSS2 EPAS1

5.98e-05196945ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

FBLN1 DPYSL3 MYH10 PPFIBP1 DIP2C

6.12e-05197945f1c8936986123a3151140c374fcd62d6705c530b
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

DOCK9 SLCO4A1 FNBP1L ITGB4 EPAS1

6.12e-051979457caa2c86dc4d50b57a7db8f7278d1588282ad6db
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

DOCK9 SLCO4A1 FNBP1L ITGB4 EPAS1

6.12e-05197945951f18f326967206adbbfc422cce9eea3d2e0854
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

FBLN1 DPYSL3 MYH10 DIP2C SERPINH1

6.12e-05197945fb847f2277609c31fffcdf49517243ce0684facf
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPYSL3 MYH10 SPHK1 PPFIBP1 DOCK9

6.12e-05197945407231542fa1ffd540dcb61435c0575e71f59725
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS10 FBLN1 MYH10 SERPINH1 HACD1

6.12e-051979458c728cd3c0382c4f3e4b78647b6e1447bb40ace1
ToppCellFibroblasts-DKK3+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

FAM114A1 DPYSL3 PPFIBP1 DNM1 SERPINH1

6.27e-051989454f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

FBLN1 DPYSL3 MYH10 CDH23 SERPINH1

6.27e-051989453ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell(6)_Endothelial_cells|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

PPFIBP1 DOCK9 SLCO4A1 ITGB4 EPAS1

6.27e-05198945f38f49d532fa6211f57e36ee494478bdd3f4f89c
ToppCelltumor_Lung-Fibroblasts-Myofibroblasts|tumor_Lung / Location, Cell class and cell subclass

FBLN1 FAM114A1 DPYSL3 PPFIBP1 SERPINH1

6.27e-0519894531f9181dab689aabe9c6182c2ef7de65ba3f0ff6
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIFAP3 MYH10 DNM1 RIMS2 SCAI

6.27e-051989458ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellFibroblasts-HLA-DRA_high_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

FBLN1 DPYSL3 PPFIBP1 SERPINH1 EPAS1

6.27e-05198945e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPFIBP1 DOCK9 SLCO4A1 PAPSS2 EPAS1

6.27e-051989452400f8b8c51739ea2ae2b9f24f44eaeefa2bb6fc
ToppCell(6)_Endothelial-E|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

PPFIBP1 DOCK9 SLCO4A1 PAPSS2 EPAS1

6.27e-05198945a5e1b321376caf262ea48904d31afd1b8e9d3be2
ToppCellmedial-2-Endothelial-Capillary_Aerocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PPFIBP1 DOCK9 SLCO4A1 PAPSS2 EPAS1

6.42e-05199945c5048b31649a0b7eddcd481b0458ed96508f5561
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PPFIBP1 DOCK9 SLCO4A1 FNBP1L EPAS1

6.42e-051999457ed541309808f15d65a9c4b26be2050e077539e6
ToppCelldistal-Endothelial-Capillary_Intermediate_2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DPYSL3 PPFIBP1 SLCO4A1 FNBP1L EPAS1

6.42e-05199945b44712baede833ddbac3699162b7eeb6ede2af27
ToppCelldistal-Endothelial-Capillary_Intermediate_2-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DPYSL3 PPFIBP1 SLCO4A1 FNBP1L EPAS1

6.42e-05199945a5c2c676fc0dd4f0422fbcae34ad6d734edd5349
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PPFIBP1 DOCK9 SLCO4A1 PAPSS2 EPAS1

6.42e-051999451621ce2968f3100e4c39e0ef8293232a5d76c614
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPFIBP1 DOCK9 SLCO4A1 PAPSS2 EPAS1

6.42e-051999456cfe5a3d0ad530411ebc11decb4ab4c529e018d5
ToppCellmedial-Endothelial-Capillary_Aerocyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PPFIBP1 DOCK9 SLCO4A1 PAPSS2 EPAS1

6.42e-0519994584e30c39c2f050aa64af167999824c1cba32ba05
ToppCellnormal_Pleural_Fluid-Epithelial_cells|normal_Pleural_Fluid / Location, Cell class and cell subclass

DPYSL3 SMARCA1 LMO3 FNBP1L SERPINH1

6.42e-05199945564ba7acd03be2d6e4d0850cb2c7237a788dc275
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PPFIBP1 DOCK9 SLCO4A1 FNBP1L EPAS1

6.42e-0519994514a7c4cf4bb3d43fd32ec9cc74f6625b225ffaa1
ToppCellmedial-Endothelial-Capillary_Aerocyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PPFIBP1 DOCK9 SLCO4A1 PAPSS2 EPAS1

6.42e-05199945f1039d1ab498fc58f0feba545df05833c235db74
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPFIBP1 DOCK9 SLCO4A1 PAPSS2 EPAS1

6.58e-052009453767abc75176779198505ebc6967d55ce322d9fe
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-BMP_responsible_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

CDH23 PAPSS2 RBM47 SERPINH1 EPAS1

6.58e-052009458433f4d3e26f6706bc7f06597d10b89221ce6437
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Artery-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DOCK9 SLCO4A1 PAPSS2 ITGB4 EPAS1

6.58e-05200945622206c33640cb2694fe158e8dc55515bb7bd4f5
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_capillary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PPFIBP1 DOCK9 SLCO4A1 FNBP1L EPAS1

6.58e-052009455ab588808c1fc384019413401ab4bf9bc06bf529
ToppCellBiopsy_Other_PF-Endothelial|Biopsy_Other_PF / Sample group, Lineage and Cell type

PPFIBP1 DOCK9 SLCO4A1 SERPINH1 EPAS1

6.58e-05200945f9916134486fb1dac55f5e7e8deb35e7a3b85770
ToppCellLPS_only-Endothelial-Endothelial-Vein|LPS_only / Treatment groups by lineage, cell group, cell type

DPYSL3 DOCK9 SERPINH1 ITGB4 EPAS1

6.58e-05200945b036f5e22c95a3b14391785b6e91aa183b9bc9a8
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Artery|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DOCK9 SLCO4A1 PAPSS2 ITGB4 EPAS1

6.58e-052009455b4a54cd81bc4d9f5e92798362239e1aa1b70bee
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPFIBP1 DOCK9 SLCO4A1 PAPSS2 EPAS1

6.58e-05200945e0a003d2a5fd6adfcb817c9bc5dceb9c79e7491b
ToppCellParenchymal-10x5prime-Endothelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DPYSL3 PPFIBP1 DOCK9 SLCO4A1 EPAS1

6.58e-052009450e648e9eb96c83a94505d07323785a7a40997eb0
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_venous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DPYSL3 DOCK9 SLCO4A1 ITGB4 EPAS1

6.58e-05200945cb00760ae75c30b1cb8526534aabd4ffc7c21000
ToppCelldistal-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PPFIBP1 DOCK9 SLCO4A1 FNBP1L EPAS1

6.58e-052009457a355c3883fd409b2e0868164bb6e7ce4b745776
ToppCell(5)_Fibroblasts|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

FBLN1 FAM114A1 DPYSL3 MYH10 SERPINH1

6.58e-0520094522c839f27d3abdf86bfabdfa305f205dd899a9dc
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FBLN1 FAM114A1 DPYSL3 DNM1 SERPINH1

6.58e-052009454dbe21cb63569f28c7017cda065ea5ee00d7254e
ToppCelldistal-2-Endothelial-Capillary|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PPFIBP1 DOCK9 SLCO4A1 FNBP1L EPAS1

6.58e-052009458daf09d63c2fda6da6e5b66f96e7449ee8b17029
ToppCellmedial-Endothelial|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PPFIBP1 DOCK9 SLCO4A1 FNBP1L EPAS1

6.58e-05200945e889b593c2ae53c42944213ce8672cd886917105
ToppCelldistal-Endothelial-Capillary|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PPFIBP1 DOCK9 SLCO4A1 FNBP1L EPAS1

6.58e-052009450ee29b2bd9cd3a1c80e0535017814f752c3eb1fa
ToppCellmedial-2-Endothelial|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PPFIBP1 DOCK9 SLCO4A1 FNBP1L EPAS1

6.58e-0520094570440db2d8be1e29aeb34ea5e8ac72641b5c056f
ToppCellParenchyma_COVID-19-Stromal-TX-Fibroblasts-4|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

FBLN1 FAM114A1 DPYSL3 DNM1 SERPINH1

6.58e-05200945bde938e5a18844fb8cc1d1be5a086809f7e2b97d
ToppCellLung_Parenchyma-Control-Endothelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PPFIBP1 DOCK9 SLCO4A1 ITGB4 EPAS1

6.58e-0520094541ac6adbf61763aa8a81a0ed586c4a5542a42cc5
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PPFIBP1 DOCK9 SLCO4A1 PAPSS2 EPAS1

6.58e-0520094530dc7ffef2052ee8610cdca952ca12f240bcec50
ToppCellBiopsy_Other_PF-Endothelial-Endothelial_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

PPFIBP1 DOCK9 SLCO4A1 SERPINH1 EPAS1

6.58e-0520094540d57a383c79d3365e033d08efd9371f0bc5bf55
ToppCelldistal-2-Endothelial-Capillary_Intermediate_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PPFIBP1 DOCK9 SLCO4A1 FNBP1L PAPSS2

6.58e-052009457a99f28670ffb8ece7873d8a9bcd2a3936d0255d
Drug4-imidazolone-5-propionic acid

AMDHD1 APOBEC3G APOBEC3F

1.27e-066923CID000000128
Drugformylglutamate

AMDHD1 APOBEC3G APOBEC3F

2.21e-067923CID000102672
DrugBepridil hydrochloride [74764-40-2]; Up 200; 10uM; HL60; HT_HG-U133A

FBLN1 FAM114A1 WASHC4 CSNK1G1 UNC45A RIMS2 RBM47

1.39e-051949271274_UP
DrugHexylcaine hydrochloride [532-76-3]; Up 200; 13.4uM; HL60; HT_HG-U133A

FBLN1 RAPSN CAPN3 HUWE1 RIMS2 PAPSS2 ITGB4

1.59e-051989272708_UP
Drug5-bromo-2-pyrimidinone

APOBEC3G APOBEC3F

1.62e-052922CID000101494
DiseaseDNA dC->dU-editing enzyme APOBEC-3G measurement

APOBEC3G APOBEC3F

2.94e-053932EFO_0802473
DiseaseUsher syndrome, type 1A

USH1G CDH23

9.77e-055932C2931205
DiseaseUSHER SYNDROME, TYPE IB (disorder)

USH1G CDH23

9.77e-055932C1848638
DiseaseUSHER SYNDROME, TYPE IA, FORMERLY

USH1G CDH23

9.77e-055932C1848639
DiseaseUSHER SYNDROME, TYPE I, FRENCH VARIETY, FORMERLY

USH1G CDH23

9.77e-055932C1848640
DiseaseUsher syndrome type 1

USH1G CDH23

9.77e-055932cv:C1568247
DiseaseUsher Syndrome, Type I

USH1G CDH23

1.46e-046932C1568247
DiseaseHereditary retinal dystrophy

USH1G CDH23

2.04e-047932C0154860
DiseaseUsher syndrome

USH1G CDH23

2.04e-047932cv:C0271097
Diseasemonocyte percentage of leukocytes

RAPSN POLR1A SPHK1 RRP12 CSNK1G1 CAPN3 CDH23 RBM47 ARCN1

5.05e-04731939EFO_0007989
Diseaseurate measurement

SEC14L3 DOCK3 RAPSN NT5C2 FNBP1L RBM47 EPAS1 DNAH1 KLB FARP2

5.22e-048959310EFO_0004531
Diseasesleep duration, high density lipoprotein cholesterol measurement

S100A7 INTS10 RAPSN NUP93

5.93e-04121934EFO_0004612, EFO_0005271
Diseasecholesterol to total lipids in large HDL percentage

INTS10 RAPSN NUP93

7.06e-0455933EFO_0022234
DiseaseP wave duration

RAPSN EPAS1

1.00e-0315932EFO_0005094
Diseaseshigellosis

CHAF1B YME1L1

1.15e-0316932EFO_0005585
Diseasephosphatidylcholine 38:6 measurement

RAPSN PTPRA

1.15e-0316932EFO_0010388
Diseasetriglyceride measurement, phospholipid measurement

INTS10 RAPSN CAPN3 DNAH1

1.19e-03146934EFO_0004530, EFO_0004639
Diseaseneutrophil count

SEC14L3 KIFAP3 RAPSN PTPRA PPP2R2D ERAP2 SPHK1 NTRK1 RRP12 CSNK1G1 CDH23 FARP2

1.33e-0313829312EFO_0004833
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

INTS10 RAPSN CAPN3 HELZ2 NUP93

1.51e-03264935EFO_0008317, EFO_0020944
Diseasephospholipids in large HDL measurement

INTS10 RAPSN NUP93

1.61e-0373933EFO_0022190
Diseasetotal lipids in large HDL

INTS10 RAPSN NUP93

1.67e-0374933EFO_0022189
Diseasefree cholesterol in large HDL measurement

INTS10 RAPSN NUP93

2.02e-0379933EFO_0022157
Diseasecholesterol in large HDL measurement

INTS10 RAPSN NUP93

2.09e-0380933EFO_0021900
DiseaseAtaxia

YME1L1 ARCN1

2.81e-0325932C0004134
Diseasediacylglycerol 34:2 measurement

INTS10 RAPSN

2.81e-0325932EFO_0010353

Protein segments in the cluster

PeptideGeneStartEntry
AMKGHMECVRYLDSI

USH1G

106

Q495M9
SRHSMDMKFTYCDDR

EPAS1

246

Q99814
RRIKKVTHDMDMCYG

NT5C2

421

P49902
MKPHFRNTVERMYRD

APOBEC3G

1

Q9HC16
RKMADLHAVPRGMYD

DPYSL3

486

Q14195
FRKYDHMRAAILEKM

AP1G2

571

O75843
EARSYRMFHDDSMKS

CHAF1B

221

Q13112
DVKFSHSGRYMMTRD

PPP2R2D

296

Q66LE6
YITEGNKDMAFRMDR

CDH23

1566

Q9H251
VADKMMVAYHGRRDV

ADAMTS10

246

Q9H324
TFGMAEEYHRESMLV

NUP93

121

Q8N1F7
FERAGKIYEFRLMME

RBM46

81

Q8TBY0
RIYELRLMMDFDGKN

RBM47

96

A0AV96
TAHSEMGRYKEMLKF

RAPSN

51

Q13702
QTELYAHFMSRKRDM

INO80

391

Q9ULG1
YGDILHRMKDLCRYM

INTS10

281

Q9NVR2
LMAARYGHLDMVEFL

FEM1C

46

Q96JP0
FMREKEYLQVMHFDT

PAPSS2

271

O95340
EERIMELHKTYRGMT

EPB41L1

251

Q9H4G0
LMVFEYMRHGDLNRF

NTRK1

586

P04629
GRYMEHLEKIMEVNE

KIAA0895

496

Q8NCT3
RPFYKRMDRIMESHL

MAN2A1

511

Q16706
DEGRVDGRMLHYMTV

PPFIBP1

741

Q86W92
DEMLRMYHALKEALS

DNM1

726

Q05193
RDDLEALGHMFMYFL

CSNK1G1

231

Q9HCP0
IKVMYMGEEHLFSVE

HSPH1

101

Q92598
RRDDLEALGHMFMYF

CSNK1G2

231

P78368
LMERKAATVECMYGH

FBXO31

196

Q5XUX0
AFEMVMRAKDNVYHL

LMO3

86

Q8TAP4
RYVKRHLTIMMDIDG

LMAN2L

216

Q9H0V9
MRRSYDAGFKLMVVE

POGK

196

Q9P215
TRDHKYAMMFAELKS

HUWE1

1786

Q7Z6Z7
GFKEDHYMLRENLMA

ITGB4

756

P16144
DFLMEMGFRMDHEFV

MED18

116

Q9BUE0
ETMSMYNPRKTHDRE

PPP1R3A

821

Q16821
ERQKEMMYFGGHSLE

RIMS2

596

Q9UQ26
LRDSFDIIKRYMDGM

FBLN1

641

P23142
MKHDAKMRYLSDDVD

CCSER2

381

Q9H7U1
RLMRHFNYLSFAEMD

DNAH1

2356

Q9P2D7
MKPHFRNTVERMYRD

APOBEC3F

1

Q8IUX4
HYDFGMRAVKSVLVM

DNAH6

1641

Q9C0G6
MMRASLYHEFPGLDK

DOCK3

1621

Q8IZD9
ANYREMAKELSEIMH

DOCK9

2051

Q9BZ29
EEMAHRVYGELMRYA

FNBP1L

91

Q5T0N5
AIAMVRFYMEKGTHR

HACD1

91

B0YJ81
GALDEAMELRGMRYH

DIP2C

1441

Q9Y2E4
LFIVVDKERYDMMGR

ADAM9

216

Q13443
ETRPDYCMKRHLSDM

ELP3

221

Q9H9T3
RVHEFAMKLAGATYM

AMDHD1

96

Q96NU7
FYHMMDRRNISDISE

ERAP2

706

Q6P179
LEMLARMKVTHYRFA

KLB

586

Q86Z14
RLYEREDHKGLMMEL

CRYGC

91

P07315
TEMYHEIMRALKAAS

ECI2

166

O75521
LGFRAAHIMVKEYMI

HELZ2

1516

Q9BYK8
EIARKLEMYGIRFHM

FARP2

221

O94887
LEMYGIRFHMASDRE

FARP2

226

O94887
ITMRYADKHMNIDFD

CAPN3

766

P20807
LRKYMEFRKTMDIDH

SEC14L3

56

Q9UDX4
AERSIIGMIDMFHKY

S100A7A

6

Q86SG5
ELHGMIMLRISDDKY

ARCN1

296

P48444
DRMAAMFYIGAHRGL

MAP3K19

1271

Q56UN5
ENIIEMYRGKKRHEM

MYH10

136

P35580
VLYHISMDDRFKSMF

KIFAP3

406

Q92845
MMHTERKVDVYGFVS

PTPRA

461

P18433
LTMERTAHYGMLFDE

FAM114A1

281

Q8IWE2
HMERDSYPRFLKSEM

RGS13

131

O14921
MEGFYLRRSHELQGM

OR1N2

1

Q8NGR9
EYFRMELMHAEKLRK

UTP6

181

Q9NYH9
HLYMMSEVLAKEEAR

STAP2

131

Q9UGK3
HMMGKRVDYAARSVI

POLR1A

431

O95602
ICMLHKMGFDRENVY

SMARCA1

971

P28370
YMEAREGMHLKNVDF

TMEM151B

266

Q8IW70
HKMVDNRGFMVTRSY

SERPINH1

216

P50454
MEAIGKLSDDMRRHF

RRP12

986

Q5JTH9
YAVMRAAEMHQLKDS

SLCO4A1

341

Q96BD0
DHKMAMDGYRRILNL

GTF3C3

266

Q9Y5Q9
MLDPYREEMTGRNFH

AKAP17A

191

Q02040
RIFYNKHMLDMDDLA

SENP5

561

Q96HI0
RMDSNVLFLKYEDMH

SULT4A1

186

Q9BR01
KARMEHSRELLRGMY

TRIM51

216

Q9BSJ1
AERSIIGMIDMFHKY

S100A7

6

P31151
IGMIDMFHKYTRRDD

S100A7

11

P31151
MRMHKIFRETRNYPE

SCAI

551

Q8N9R8
EMAMDTMIRIFHRYS

S100Z

6

Q8WXG8
DSDYHKERMILPMSR

USP9Y

866

O00507
IFEGYRSMFMEPAKR

YME1L1

76

Q96TA2
KARMEHSRELLRGMY

TRIM51G

216

A0A3B3IT33
RKEGPLMDMRQHEEY

WDR55

156

Q9H6Y2
ELLKAIEHMFYRRSM

WASHC4

481

Q2M389
RLFLAMEKGRHMEYE

SPHK1

301

Q9NYA1
RKAYLEDFYTRMMHE

PIPOX

56

Q9P0Z9
EDSRFIDHLMVMFGE

TTC4

296

O95801
KIERHAMYCNGLMEE

UIMC1

516

Q96RL1
AVHRKMMRTELYFLS

USP6

876

P35125
EGYMFEEHEMIRRAA

UNC45A

781

Q9H3U1
AHEFLMFTVDAMRKA

USP17L10

161

C9JJH3
TNMHLRLFELAKDYM

NMNAT1

21

Q9HAN9