Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionchromatin binding

H1-10 H3-5 CGAS SAP30L POU4F1 MED1 MECP2 AHDC1 HNRNPC MEOX1 CRX MSH6 TNRC18 THRA TOX3 H3-3A CHD6 VCX TOP2B

1.75e-0873910919GO:0003682
GeneOntologyMolecularFunctionchromatin DNA binding

H1-10 H3-5 MED1 MECP2 AHDC1 HNRNPC THRA TOX3 H3-3A

3.36e-071671099GO:0031490
GeneOntologyMolecularFunctionstructural constituent of chromatin

H1-10 H3-5 H3-4 H3-7 H3C15 H3C1 H3-3A

1.25e-061001097GO:0030527
GeneOntologyMolecularFunctionnucleosome binding

H1-10 H3-5 CGAS SAP30L HNRNPC H3-3A

1.61e-05981096GO:0031491
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

MSH6 IGHMBP2 RECQL5 CHD6 XRCC6 TOP2B

6.97e-051271096GO:0008094
GeneOntologyMolecularFunctionhelicase activity

DDX46 IGHMBP2 RECQL5 DDX23 CHD6 XRCC6

2.31e-041581096GO:0004386
GeneOntologyMolecularFunctionhistone reader activity

MECP2 MDC1 HDGFL2

3.75e-04261093GO:0140566
GeneOntologyMolecularFunctionDNA insertion or deletion binding

XPC MSH6

4.37e-0461092GO:0032135
GeneOntologyMolecularFunctionnucleosomal DNA binding

H1-10 H3-5 HNRNPC H3-3A

4.94e-04671094GO:0031492
GeneOntologyMolecularFunctionATP-dependent activity

KIF21B ATP10A MSH6 DDX46 IGHMBP2 RECQL5 DDX23 MACF1 CHD6 XRCC6 TOP2B

5.34e-0461410911GO:0140657
GeneOntologyMolecularFunctioncadherin binding

H1-10 LRRC59 H3C1 CTNNA3 MACF1 CTNNA1 GOLGA3 NOTCH3

5.46e-043391098GO:0045296
GeneOntologyMolecularFunctionATP hydrolysis activity

KIF21B ATP10A DDX46 IGHMBP2 RECQL5 DDX23 MACF1 CHD6 XRCC6

7.00e-044411099GO:0016887
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

DIS3L2 MSH6 DDX46 PDE12 IGHMBP2 RECQL5 POP1 DDX23 CHD6 XRCC6 TOP2B

8.01e-0464510911GO:0140640
GeneOntologyMolecularFunctiontranscription factor binding

POU4F1 XPC MED1 MECP2 CRX THRA IGHMBP2 SORBS3 CHD6 UHRF2 FOXF2 BRMS1

8.35e-0475310912GO:0008134
GeneOntologyMolecularFunctionstructural molecule activity

H1-10 H3-5 ANK2 LAMC3 H3-4 H3-7 H3C15 MAGI2 H3C1 SORBS3 MACF1 H3-3A CTNNA1

1.14e-0389110913GO:0005198
GeneOntologyMolecularFunctionchromatin-protein adaptor activity

MECP2 MDC1 HDGFL2

1.45e-03411093GO:0140463
GeneOntologyMolecularFunctionDNA secondary structure binding

XPC MECP2 MSH6

1.45e-03411093GO:0000217
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

IRF2BP2 ANK2 CGAS SAP30L XPC SSX8P MED1 BCL9 MECP2 HNRNPC PHF2 MAGI2 MDC1 TOX3 HDGFL2

1.58e-03116010915GO:0030674
GeneOntologyMolecularFunctionvinculin binding

SORBS3 CTNNA1

2.21e-03131092GO:0017166
GeneOntologyMolecularFunctionmismatched DNA binding

XPC MSH6

2.57e-03141092GO:0030983
GeneOntologyMolecularFunctionmolecular adaptor activity

IRF2BP2 ANK2 CGAS SAP30L XPC SSX8P MED1 BCL9 MECP2 AHDC1 HNRNPC PHF2 MAGI2 MDC1 TOX3 HDGFL2

2.78e-03135610916GO:0060090
GeneOntologyBiologicalProcessprotein-DNA complex organization

CDKN1C H1-10 ACTR8 HIRIP3 MED1 H3-4 H3C15 MECP2 HNRNPC PRDM2 PHF2 THRA H3C1 MDC1 DDX23 H3-3A CHD6 UHRF2 HDGFL2 VCX

1.82e-0799910720GO:0071824
GeneOntologyBiologicalProcesschromatin organization

CDKN1C H1-10 ACTR8 HIRIP3 H3-4 H3C15 MECP2 HNRNPC PRDM2 PHF2 H3C1 MDC1 DDX23 H3-3A CHD6 UHRF2 HDGFL2 VCX

7.74e-0789610718GO:0006325
GeneOntologyBiologicalProcesschromatin remodeling

CDKN1C H1-10 ACTR8 H3-4 H3C15 MECP2 HNRNPC PRDM2 PHF2 H3C1 DDX23 H3-3A CHD6 UHRF2 HDGFL2

6.51e-0674110715GO:0006338
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase II

CDKN1C IRF2BP2 TRO SAP30L POU4F1 POU6F1 MED1 MECP2 PRDM2 ZNF512B IFNG THRA ZNF608 IGHMBP2 SORBS3 NOTCH3 FOXF1 BRMS1

7.48e-06105310718GO:0000122
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

CDKN1C IRF2BP2 TRO SAP30L POU4F1 POU6F1 MED1 MECP2 PRDM2 ZNF512B IFNG THRA ZNF608 IGHMBP2 RECQL5 SORBS3 XRCC6 NOTCH3 FOXF1 FOXF2 BRMS1

8.79e-06139910721GO:0045892
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

CDKN1C IRF2BP2 TRO SAP30L POU4F1 POU6F1 MED1 MECP2 PRDM2 ZNF512B IFNG THRA ZNF608 IGHMBP2 RECQL5 SORBS3 XRCC6 NOTCH3 FOXF1 FOXF2 BRMS1

1.02e-05141310721GO:1902679
GeneOntologyBiologicalProcessDNA recombination

H1-10 ACTR8 CGAS IFNG MSH6 RECQL5 HDGFL2 XRCC6 TOP2B

1.28e-043681079GO:0006310
GeneOntologyBiologicalProcessregulation of DNA recombination

H1-10 CGAS IFNG MSH6 RECQL5 HDGFL2

1.32e-041501076GO:0000018
GeneOntologyCellularComponentchromatin

H1-10 ACTR8 H3-5 SAP30L POU4F1 XPC POU6F1 MED1 H3-4 H3-7 H3C15 MECP2 HNRNPC MEOX1 CRX MEOX2 MSH6 THRA H3C1 DDX23 H3-3A CHD6 UHRF2 TOP2B FOXF1 FOXF2 BRMS1

6.80e-09148010927GO:0000785
GeneOntologyCellularComponentnucleosome

H1-10 H3-5 H3-4 H3-7 H3C15 H3C1 H3-3A

7.98e-061381097GO:0000786
DomainHISTONE_H3_1

H3-5 H3-4 H3C1 H3-3A

3.52e-0871074PS00322
DomainHISTONE_H3_2

H3-5 H3-4 H3C1 H3-3A

7.00e-0881074PS00959
DomainHistone_H3/CENP-A

H3-5 H3-4 H3C1 H3-3A

7.00e-0881074IPR000164
DomainH3

H3-5 H3-4 H3C1 H3-3A

7.00e-0881074SM00428
DomainVCX_VCY

VCX2 VCX3A VCX

1.81e-0651073PF15231
DomainVCX/VCY1

VCX2 VCX3A VCX

1.81e-0651073IPR026653
DomainAlpha_catenin

CTNNA3 CTNNA1

1.94e-0441072IPR001033
DomainVINCULIN_1

CTNNA3 CTNNA1

1.94e-0441072PS00663
DomainVinculin_CS

CTNNA3 CTNNA1

1.94e-0441072IPR000633
DomainHistone_H2A/H2B/H3

H3-5 H3-4 H3C1 H3-3A

2.97e-04561074IPR007125
DomainHistone

H3-5 H3-4 H3C1 H3-3A

2.97e-04561074PF00125
DomainVinculin

CTNNA3 CTNNA1

3.22e-0451072PF01044
DomainHSR

SP110 SP140

3.22e-0451072PS51414
DomainHSR

SP110 SP140

3.22e-0451072PF03172
DomainHSR_dom

SP110 SP140

3.22e-0451072IPR004865
DomainDEXDc

DDX46 IGHMBP2 RECQL5 DDX23 CHD6

4.09e-041091075SM00487
DomainHelicase_ATP-bd

DDX46 IGHMBP2 RECQL5 DDX23 CHD6

4.27e-041101075IPR014001
Domain-

H3-5 H3-4 H3C1 H3-3A

6.61e-046910741.10.20.10
DomainVinculin/catenin

CTNNA3 CTNNA1

6.70e-0471072IPR006077
DomainSAND_dom

SP110 SP140

8.90e-0481072IPR000770
DomainSAND

SP110 SP140

8.90e-0481072PF01342
DomainSAND

SP110 SP140

8.90e-0481072PS50864
DomainSAND

SP110 SP140

8.90e-0481072SM00258
DomainPHD

SP110 PHF2 UHRF2 SP140

9.05e-04751074PF00628
DomainZnf_PHD-finger

SP110 PHF2 UHRF2 SP140

1.10e-03791074IPR019787
DomainHistone-fold

H3-5 H3-4 H3C1 H3-3A

1.32e-03831074IPR009072
DomainPHD

SP110 PHF2 UHRF2 SP140

1.71e-03891074SM00249
DomainZnf_PHD

SP110 PHF2 UHRF2 SP140

1.86e-03911074IPR001965
Domain-

SP110 SP140

2.07e-031210723.10.390.10
DomainSAND_dom-like

SP110 SP140

2.07e-03121072IPR010919
DomainZF_PHD_2

SP110 PHF2 UHRF2 SP140

2.17e-03951074PS50016
DomainZF_PHD_1

SP110 PHF2 UHRF2 SP140

2.26e-03961074PS01359
DomainHelicase_C

DDX46 RECQL5 DDX23 CHD6

3.34e-031071074PF00271
DomainHELICc

DDX46 RECQL5 DDX23 CHD6

3.34e-031071074SM00490
DomainHelicase_C

DDX46 RECQL5 DDX23 CHD6

3.46e-031081074IPR001650
DomainHELICASE_CTER

DDX46 RECQL5 DDX23 CHD6

3.57e-031091074PS51194
DomainHELICASE_ATP_BIND_1

DDX46 RECQL5 DDX23 CHD6

3.57e-031091074PS51192
DomainPOU

POU4F1 POU6F1

3.70e-03161072SM00352
DomainPOU_dom

POU4F1 POU6F1

3.70e-03161072IPR000327
DomainPou

POU4F1 POU6F1

3.70e-03161072PF00157
DomainPOU_1

POU4F1 POU6F1

3.70e-03161072PS00035
DomainPOU_2

POU4F1 POU6F1

3.70e-03161072PS00465
DomainPOU_3

POU4F1 POU6F1

3.70e-03161072PS51179
DomainPOU

POU4F1 POU6F1

4.18e-03171072IPR013847
PathwayKEGG_MEDICUS_VARIANT_IGH_MMSET_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION

H3-5 H3-4 H3C15 H3C1 H3-3A

6.83e-0819835M47442
PathwayREACTOME_SUMOYLATION

XPC CDCA8 HNRNPC THRA MDC1 UHRF2 TOP2B

6.07e-05169837MM14919
PathwayREACTOME_SUMOYLATION

XPC CDCA8 HNRNPC THRA MDC1 UHRF2 TOP2B

1.22e-04189837M27214
PathwayKEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS

H3-5 H3-4 H3C15 IFNG H3C1 H3-3A

1.67e-04139836M4741
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

BCL9 H3-4 H3C15 H3C1 H3-3A

1.96e-0491835M27101
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

ARHGEF18 CDCA8 H3C15 HNRNPC ZNF512B H3C1 FAM13A VANGL1 ARHGEF1 BTK H3-3A CTNNA1 GOLGA3

2.79e-047208313M41838
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

IRF2BP2 H1-10 PPAN SRSF6 HIRIP3 SAP30L TATDN2 XPC GPATCH8 MED1 BCL9 MECP2 HNRNPC PRDM2 PCF11 MSH6 DDX46 FAM13A MDC1 POP1 SORBS3 AFF1 SCAF11 CTNNA1 XRCC6 TOP2B

3.02e-197741132615302935
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

H1-10 ACTR8 SRSF6 HIRIP3 SAP30L LRRC59 XPC GPATCH8 MED1 SP110 MECP2 AHDC1 HNRNPC PRDM2 ZNF512B PHF2 DDX46 H3C1 FBXO28 RECQL5 MDC1 POP1 DDX23 SCAF11 CHD6 HDGFL2 XRCC6 TOP2B BRMS1

9.80e-1712941132930804502
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

HIRIP3 LRRC59 XPC GPATCH8 MED1 CDCA8 MECP2 PRDM2 ZNF512B PHF2 MSH6 RECQL5 MDC1 H3-3A SCAF11 CHD6 UHRF2 HDGFL2 XRCC6 TOP2B

9.13e-156081132036089195
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

H1-10 H3-5 SRSF6 LRRC59 MED1 H3-4 CDCA8 H3C15 MECP2 HNRNPC ZNF512B PCF11 PHF2 DDX46 H3C1 RECQL5 MDC1 H3-3A SCAF11 HDGFL2 XRCC6 TOP2B

4.78e-139541132236373674
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

PPAN H3-5 ANK2 NHSL2 TRO LRRC59 XPC H3-4 H3C15 MECP2 HNRNPC PCF11 TNRC18 H3C1 ZNF608 EFCAB12 DDX23 MACF1 H3-3A CHD6 HDGFL2 XRCC6 TOP2B

2.19e-1014421132335575683
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

EPS8 PPAN XPC GPATCH8 MED1 H3C15 MECP2 AHDC1 PCF11 PHF2 MSH6 DDX46 H3C1 VANGL1 FBXO28 IGHMBP2 RECQL5 MDC1 POP1 MACF1 SCAF11 CHD6 HDGFL2

4.52e-1014971132331527615
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

H1-10 PPAN SRSF6 LRRC59 H3C15 HNRNPC ZNF512B MSH6 DDX46 MDC1 DDX23 SCAF11 HDGFL2 XRCC6 TOP2B

1.28e-096051131528977666
Pubmed

Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.

H1-10 PPAN SRSF6 LRRC59 MED1 H3C15 MECP2 HNRNPC MSH6 POP1 DDX23 HDGFL2 XRCC6

2.24e-094411131331239290
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

LRRC59 MED1 MECP2 PCF11 MSH6 DDX46 MDC1 SCAF11 HDGFL2 XRCC6 TOP2B

2.38e-092831131130585729
Pubmed

A standardized nomenclature for mammalian histone genes.

H1-10 H3-5 H3-4 H3-7 H3C15 H3C1 H3-3A

4.76e-0974113736180920
Pubmed

Crystal structure of DPF3b in complex with an acetylated histone peptide.

H3-5 H3-4 H3C1 H3-3A

1.31e-089113427402533
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SRSF6 LRRC59 XPC GPATCH8 MED1 MECP2 AHDC1 HNRNPC ZNF512B PCF11 PHF2 MSH6 DDX46 DDX23 MACF1 CHD6 XRCC6 TOP2B

1.35e-0810821131838697112
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

IRF2BP2 MED1 BCL9 AHDC1 ZNF512B PCF11 TNRC18 ZNF608 MDC1 BRMS1

1.93e-082681131033640491
Pubmed

Ligand-dependent activation of the farnesoid X-receptor directs arginine methylation of histone H3 by CARM1.

H3-7 H3C15 H3C1 H3-3A

3.43e-0811113415471871
Pubmed

Human PAD4 regulates histone arginine methylation levels via demethylimination.

H3-4 H3-7 H3C15 H3-3A

3.43e-0811113415345777
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

H1-10 ACTR8 HIRIP3 XPC MED1 HNRNPC MDC1 POP1 DDX23 SCAF11 XRCC6

7.10e-083941131127248496
Pubmed

Expression patterns and post-translational modifications associated with mammalian histone H3 variants.

H3-7 H3C15 H3C1 H3-3A

1.03e-0714113416267050
Pubmed

A member of a gene family on Xp22.3, VCX-A, is deleted in patients with X-linked nonspecific mental retardation.

VCX2 VCX3A VCX

1.33e-074113310903929
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

H1-10 HIRIP3 XPC H3C15 POP1 DDX23 SCAF11 HDGFL2 TOP2B

1.43e-07251113931076518
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

H1-10 PPAN SRSF6 LRRC59 CDCA8 H3C15 HNRNPC ZNF512B DDX46 VANGL1 MDC1 DDX23 MACF1 CTNNA1 XRCC6 TOP2B

2.18e-0710241131624711643
Pubmed

Interaction network of human early embryonic transcription factors.

BCL9 AHDC1 PRDM2 CRX ZNF512B TNRC18 ZNF608 MDC1 CTNNA1 UHRF2

2.39e-073511131038297188
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

KIF21B EPS8 SRSF6 CGAS HNRNPC DDX46 H3C1 MDC1 DDX23 MACF1 HDGFL2 XRCC6 TOP2B

2.49e-076601131332780723
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

H1-10 PPAN SRSF6 CGAS LRRC59 HNRNPC PHF2 MSH6 DDX46 H3C1 ARHGEF1 BTK POP1 DDX23 H3-3A CHD6 XRCC6 TOP2B

2.58e-0713181131830463901
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

H1-10 SRSF6 ANK2 LRRC59 ZNF512B PCF11 PDE12 H3C1 VANGL1 POP1 C1orf52 DDX23 MACF1 CTNNA1 OCLN HDGFL2 GOLGA3 XRCC6 TOP2B

3.19e-0714871131933957083
Pubmed

Human spleen histone H3. Isolation and amino acid sequence.

H3-7 H3C15 H3-3A

3.32e-07511337309716
Pubmed

A human sex-chromosomal gene family expressed in male germ cells and encoding variably charged proteins.

VCX2 VCX3A VCX

3.32e-075113310607842
Pubmed

Modifications of human histone H3 variants during mitosis.

H3-7 H3C15 H3-3A

3.32e-075113316185088
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

IRF2BP2 MED1 BCL9 MECP2 AHDC1 PRDM2 PCF11 PHF2 MSH6 TNRC18 C1orf52 DDX23 H3-3A UHRF2 XRCC6 TOP2B

5.84e-0711031131634189442
Pubmed

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.

H3-7 H3C15 H3C1 H3-3A

6.06e-0721113411242053
Pubmed

Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation.

H3-7 H3C15 H3-3A

6.63e-076113310464286
Pubmed

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks.

H3-7 H3C15 H3-3A

6.63e-076113315525939
Pubmed

Novel mitosis-specific phosphorylation of histone H3 at Thr11 mediated by Dlk/ZIP kinase.

H3-7 H3C15 H3-3A

6.63e-076113312560483
Pubmed

Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification.

H3-7 H3C15 H3-3A

6.63e-076113317189264
Pubmed

Organismal differences in post-translational modifications in histones H3 and H4.

H3-7 H3C15 H3-3A

6.63e-076113317194708
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

H1-10 ACTR8 SAP30L XPC PPFIA3 SP110 MECP2 ZNF512B PHF2 MSH6 THRA ZNF608 VANGL1 MACF1 H3-3A SP140

6.81e-0711161131631753913
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

H1-10 PPAN SRSF6 LRRC59 XPC AHDC1 HNRNPC ZNF512B PCF11 DDX46 MDC1 POP1 SCAF11 TOP2B

6.85e-078471131435850772
Pubmed

Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.

MED1 ZNF512B PHF2 MSH6 DDX46 MDC1 XRCC6

8.28e-07156113737108203
Pubmed

Human transcription factor protein interaction networks.

IRF2BP2 H1-10 ACTR8 PPAN LRRC59 GPATCH8 BCL9 PRDM2 ZNF512B PCF11 PHF2 ZNF608 RECQL5 MDC1 SCAF11 CHD6 XRCC6 BRMS1

8.32e-0714291131835140242
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

H1-10 POU4F1 POU6F1 MED1 ANKRD6 SP110 MECP2 MEOX1 MEOX2 ZNF512B PHF2 THRA ZNF556 TOX3

1.03e-068771131420211142
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

H3-5 SRSF6 HIRIP3 PPFIA3 H3-4 NUDT13 ZNF512B H3C1 MDC1 DDX23 CHD6 GOLGA3 XRCC6

1.11e-067541131335906200
Pubmed

Phosphorylation of Ser28 in histone H3 mediated by mixed lineage kinase-like mitogen-activated protein triple kinase alpha.

H3-7 H3C15 H3-3A

1.16e-067113315684425
Pubmed

Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation.

H3-7 H3C15 H3-3A

1.16e-067113311856369
Pubmed

PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-alpha target gene activation by regulating lysine demethylase 1 specificity.

H3-4 H3C1 H3-3A

1.16e-067113320448663
Pubmed

The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment.

H3-7 H3C15 H3-3A

1.16e-067113315681610
Pubmed

Coactivator-associated arginine methyltransferase-1 enhances nuclear factor-kappaB-mediated gene transcription through methylation of histone H3 at arginine 17.

H3-7 H3C15 H3-3A

1.16e-067113316497732
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

HIRIP3 XPC MED1 CDCA8 MECP2 ZNF512B PHF2 H3C1 ZNF608 RECQL5 CHD6 XRCC6

1.34e-066451131225281560
Pubmed

Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.

SRSF6 MED1 H3-4 PCF11 MDC1

1.44e-0659113528813667
Pubmed

Epidermal development requires ninein for spindle orientation and cortical microtubule organization.

CTNNA3 CTNNA1 OCLN NOTCH3

1.49e-0626113430923192
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

H1-10 SRSF6 LRRC59 HNRNPC MSH6 TNRC18 DDX46 POP1 DDX23 CHD6 XRCC6 BRMS1

1.58e-066551131235819319
Pubmed

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.

H1-10 LRRC59 H3-4 H3C15 H3C1 MDC1 DDX23 H3-3A CTNNA1 HDGFL2 GOLGA3 XRCC6 TOP2B

1.75e-067861131329128334
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

H1-10 DIS3L2 SRSF6 CGAS XPC H3-7 HNRNPC MSH6 PDE12 ARHGEF1 RECQL5 MDC1 POP1 DDX23 MACF1 XRCC6 TOP2B

1.80e-0613531131729467282
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

H1-10 H3-5 LRRC59 H3-4 H3-7 H3C15 HNRNPC DDX46 H3C1 MDC1 POP1 DDX23 CTNNA1 XRCC6

2.59e-069491131436574265
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

SRSF6 ATP10A HNRNPC PNMA8B PCF11 DDX46 EFCAB12 MDC1 MACF1

2.93e-06361113926167880
Pubmed

Human tNASP promotes in vitro nucleosome assembly with histone H3.3.

H3-4 H3C15 H3C1 H3-3A

3.11e-0631113425615412
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

LRRC59 MED1 CDCA8 MECP2 HNRNPC NECAP1 PDE12 C1orf52 MACF1 HDGFL2

3.44e-064721131038943005
Pubmed

The functional interactome landscape of the human histone deacetylase family.

H1-10 PPAN SAP30L ZNF512B MSH6 TNRC18 H3C1 BRMS1

4.97e-06289113823752268
Pubmed

Comparative Interactomes of VRK1 and VRK3 with Their Distinct Roles in the Cell Cycle of Liver Cancer.

H1-10 SRSF6 HNRNPC PCF11 MDC1 H3-3A XRCC6

5.08e-06205113728927264
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

IRF2BP2 LRRC59 GPATCH8 MED1 MSH6 DDX46 H3C1 MDC1 DDX23 H3-3A UHRF2 HDGFL2 XRCC6 TOP2B

5.53e-0610141131432416067
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

IRF2BP2 EPS8 H1-10 MED1 MSH6 DDX46 MDC1 POP1 DDX23 HDGFL2

6.34e-065061131030890647
Pubmed

Nuclear High Mobility Group A2 (HMGA2) Interactome Revealed by Biotin Proximity Labeling.

CDCA8 ZNF512B MDC1 XRCC6

6.42e-0637113436835656
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ARHGEF18 ATP10A AHDC1 HNRNPC PHF2 TNRC18 THRA FAM13A ZNF608 TOX3 AFF1 MACF1 SCAF11 CHD6 NOTCH3 PDZD2 BRMS1

6.43e-0614891131728611215
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

H1-10 PPAN MED1 CDCA8 MSH6 DDX46 IGHMBP2 POP1 MACF1 SCAF11 XRCC6 TOP2B

7.08e-067591131235915203
Pubmed

Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.

IRF2BP2 MSH6 MDC1 GOLGA3 XRCC6

8.83e-0685113516051665
Pubmed

A phospho/methyl switch at histone H3 regulates TFIID association with mitotic chromosomes.

H3-4 PHF2 H3-3A

9.33e-0613113320953165
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

H1-10 LRRC59 H3-7 H3C15 HNRNPC RECQL5 MDC1 DDX23 H3-3A XRCC6 TOP2B

9.54e-066521131131180492
Pubmed

Nucleolar proteome dynamics.

H1-10 SRSF6 H3-4 CDCA8 HNRNPC POP1 DDX23 XRCC6 TOP2B

9.71e-06419113915635413
Pubmed

A unique H3K4me2 profile marks tissue-specific gene regulation.

H3-4 H3-3A

1.05e-052113220841431
Pubmed

Forkhead transcription factor FoxF2 is expressed in mesodermal tissues involved in epithelio-mesenchymal interactions.

FOXF1 FOXF2

1.05e-052113210822266
Pubmed

The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation.

H3C15 MECP2

1.05e-052113212427740
Pubmed

Backbone and nearly complete side-chain chemical shift assignments reveal the human uncharacterized protein CXorf51A as intrinsically disordered.

CXorf51A CXorf51B

1.05e-052113234415548
Pubmed

Structural studies of the SET domain from RIZ1 tumor suppressor.

H3-4 PRDM2

1.05e-052113218082620
Pubmed

Implication of the lymphocyte-specific nuclear body protein Sp140 in an innate response to human immunodeficiency virus type 1.

XRCC6 SP140

1.05e-052113212368356
Pubmed

UHRF2 decreases H3K9ac expression by interacting with it through the PHD and SRA/YDG domain in HepG2 hepatocellular carcinoma cells.

H3C1 UHRF2

1.05e-052113228004105
Pubmed

Differential localization of Mox-1 and Mox-2 proteins indicates distinct roles during development.

MEOX1 MEOX2

1.05e-05211329032023
Pubmed

αE-catenin is an autoinhibited molecule that coactivates vinculin.

CTNNA3 CTNNA1

1.05e-052113222586082
Pubmed

Differences in the embryonic expression patterns of mouse Foxf1 and -2 match their distinct mutant phenotypes.

FOXF1 FOXF2

1.05e-052113214745957
Pubmed

Inactivation of a histone methyltransferase by mutations in human cancers.

H3-4 PRDM2

1.05e-052113214633678
Pubmed

The single amphioxus Mox gene: insights into the functional evolution of Mox genes, somites, and the asymmetry of amphioxus somitogenesis.

MEOX1 MEOX2

1.05e-052113212051829
Pubmed

Characterization of the PR domain of RIZ1 histone methyltransferase.

PRDM2 H3C1

1.05e-052113215964548
Pubmed

Gastroparesis is associated with decreased FOXF1 and FOXF2 in humans, and loss of FOXF1 and FOXF2 results in gastroparesis in mice.

FOXF1 FOXF2

1.05e-052113230565344
Pubmed

Transcriptional regulators SP110 and SP140 modulate inflammatory response genes in Mycobacterium tuberculosis-infected human macrophages.

SP110 SP140

1.05e-052113239162523
Pubmed

DmFoxF, a novel Drosophila fork head factor expressed in visceral mesoderm.

FOXF1 FOXF2

1.05e-052113211804790
Pubmed

Differential activation of lung-specific genes by two forkhead proteins, FREAC-1 and FREAC-2.

FOXF1 FOXF2

1.05e-05211328626802
Pubmed

RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.

H1-10 PPAN SRSF6 H3-4 H3C15 MSH6 H3C1 POP1 H3-3A

1.09e-05425113921081503
Pubmed

Notch signaling differentially regulates Atoh7 and Neurog2 in the distal mouse retina.

POU4F1 CRX NOTCH3

1.18e-0514113325100656
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

H1-10 PPAN SRSF6 LRRC59 MED1 AHDC1 HNRNPC TNRC18 H3C1 ZNF608 IGHMBP2 POP1 AFF1 CTNNA1 XRCC6

1.29e-0512471131527684187
Pubmed

NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.

H1-10 DIS3L2 LRRC59 H3-4 ATP10A HNRNPC POP1 XRCC6

1.39e-05333113832665550
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

H1-10 SRSF6 LRRC59 HNRNPC MSH6 DDX46 ARHGEF1 MDC1 POP1 DDX23 MACF1 SCAF11 CTNNA1 HDGFL2 XRCC6 TOP2B

1.39e-0514151131628515276
Pubmed

Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress.

MECP2 HNRNPC PCF11 POP1 XRCC6 TOP2B

1.40e-05159113622751105
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

H1-10 PPAN SRSF6 CGAS LRRC59 MECP2 HNRNPC MSH6 H3C1 MDC1 POP1 SCAF11 CTNNA1 UHRF2 XRCC6

1.42e-0512571131536526897
Pubmed

Serine ADP-Ribosylation Depends on HPF1.

H3-4 H3C1 H3-3A

1.48e-0515113328190768
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

SRSF6 GPATCH8 HNRNPC MSH6 DDX46 DDX23 SCAF11

1.58e-05244113729884807
Pubmed

Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II.

H1-10 SRSF6 CGAS HNRNPC MDC1 ANO7 TOP2B

1.58e-05244113730349055
Pubmed

A bead-based approach for large-scale identification of in vitro kinase substrates.

PPAN HIRIP3 LRRC59 HNRNPC MSH6 HDGFL2

1.61e-05163113622113938
Pubmed

Human Asf1 regulates the flow of S phase histones during replicational stress.

H3-4 H3C1 H3-3A

1.81e-0516113315664198
Pubmed

Comparative Proteomics and Interactome Analysis of the SARS-CoV-2 Nucleocapsid Protein in Human and Bat Cell Lines.

H1-10 H3-5 SRSF6 LRRC59 HNRNPC XRCC6

1.91e-05168113639066279
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

H3-5 LRRC59 H3-4 H3-7 H3C15 HNRNPC H3C1 FBXO28 MACF1 H3-3A CTNNA1 XRCC6

2.03e-058441131225963833
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

SRSF6 HNRNPC PCF11 MSH6 DDX46 ARHGEF1 DDX23 MACF1 CTNNA1 XRCC6

2.12e-055821131020467437
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

H1-10 LRRC59 HNRNPC DDX46 PDE12 H3C1 MACF1 H3-3A CTNNA1 HDGFL2 XRCC6

2.12e-057111131133022573
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

H3-5 GPATCH8 ZNF512B H3C1 TOP2B

2.25e-05103113532744500
InteractionH3-3A interactions

CDKN1C H3-5 HIRIP3 XPC GPATCH8 MED1 H3-4 CDCA8 H3C15 MECP2 HNRNPC PRDM2 ZNF512B PHF2 MSH6 H3C1 RECQL5 MDC1 DDX23 H3-3A SCAF11 UHRF2 HDGFL2 XRCC6 TOP2B

2.22e-1374911025int:H3-3A
InteractionH3C1 interactions

CDKN1C H1-10 H3-5 ANK2 LRRC59 XPC H3-4 CDCA8 H3-7 H3C15 MECP2 PRDM2 ZNF512B MSH6 TNRC18 H3C1 RECQL5 MDC1 POP1 H3-3A UHRF2 HDGFL2 XRCC6 TOP2B PDZD2

1.27e-1190111025int:H3C1
InteractionH3C3 interactions

LRRC59 XPC MED1 CDCA8 H3-7 MECP2 PRDM2 ZNF512B PHF2 MSH6 RECQL5 MDC1 SCAF11 CHD6 UHRF2 HDGFL2 XRCC6 TOP2B

1.93e-1049511018int:H3C3
InteractionH2BC21 interactions

H1-10 H3-5 HIRIP3 CGAS XPC H3-4 CDCA8 H3-7 H3C15 MECP2 PRDM2 PHF2 MSH6 H3C1 FBXO28 MDC1 H3-3A SCAF11 XRCC6 TOP2B

1.06e-0969611020int:H2BC21
InteractionHMGA1 interactions

H1-10 H3-5 CGAS XPC H3-4 H3-7 H3C15 MECP2 TNRC18 H3C1 MDC1 H3-3A SCAF11 GOLGA3 XRCC6 TOP2B

1.07e-0941911016int:HMGA1
InteractionCBX3 interactions

XPC MED1 H3-4 SP110 CDCA8 H3C15 MECP2 AHDC1 NECAP1 ZNF512B H3C1 MDC1 C1orf52 MACF1 H3-3A UHRF2 HDGFL2 XRCC6 TOP2B

1.99e-0964611019int:CBX3
InteractionCENPA interactions

H1-10 HIRIP3 XPC CDCA8 H3-7 MECP2 PRDM2 ZNF512B PHF2 MSH6 H3-3A CHD6 HDGFL2 XRCC6 TOP2B

2.14e-0937711015int:CENPA
InteractionH2AX interactions

H3-5 SRSF6 HIRIP3 XPC GPATCH8 H3-4 H3-7 H3C15 HNRNPC MSH6 TNRC18 H3C1 MDC1 DDX23 H3-3A UHRF2 HDGFL2 XRCC6

3.41e-0959311018int:H2AX
InteractionCHD4 interactions

H1-10 PPAN H3-5 SRSF6 LAMC3 GPATCH8 H3-4 H3C15 MECP2 HNRNPC ZNF512B MSH6 DDX46 H3C1 MDC1 DDX23 H3-3A SCAF11 HDGFL2 GOLGA3 XRCC6 TOP2B

5.96e-0993811022int:CHD4
InteractionHMGN5 interactions

H1-10 XPC H3C15 PRDM2 H3C1 FBXO28 MDC1 H3-3A SCAF11 TOP2B

1.23e-0815411010int:HMGN5
InteractionH2BC8 interactions

HIRIP3 XPC H3-4 CDCA8 H3C15 MECP2 ZNF512B PHF2 MSH6 RECQL5 MDC1 C1orf52 SCAF11 CHD6 HDGFL2 XRCC6 TOP2B

1.47e-0857611017int:H2BC8
InteractionH1-0 interactions

H1-10 H3-5 CGAS WSB2 H3-4 H3C15 NECAP1 H3C1 FBXO28 POP1 H3-3A PLCE1

1.59e-0825611012int:H1-0
InteractionSMC5 interactions

H1-10 H3-5 SRSF6 LRRC59 MED1 H3-4 CDCA8 H3C15 MECP2 HNRNPC ZNF512B PCF11 PHF2 DDX46 H3C1 RECQL5 MDC1 H3-3A SCAF11 HDGFL2 XRCC6 TOP2B

1.89e-08100011022int:SMC5
InteractionXRCC6 interactions

EPS8 LRRC59 XPC MED1 MECP2 ZNF512B PCF11 PHF2 MSH6 TNRC18 DDX46 THRA H3C1 MDC1 H3-3A SCAF11 CTNNA1 UHRF2 HDGFL2 XRCC6 TOP2B

2.59e-0892811021int:XRCC6
InteractionXPC interactions

LRRC59 XPC MECP2 ZNF512B H3C1 DDX23 H3-3A ANO7 XRCC6 TOP2B

2.84e-0816811010int:XPC
InteractionPARP1 interactions

IRF2BP2 H3-5 XPC MED1 H3-4 CDCA8 H3C15 MECP2 PRDM2 NECAP1 ZNF512B PHF2 MSH6 THRA H3C1 RECQL5 POP1 H3-3A SCAF11 CHD6 CTNNA1 UHRF2 HDGFL2 XRCC6 TOP2B

3.14e-08131611025int:PARP1
InteractionPARP2 interactions

CGAS XPC H3-4 MSH6 H3C1 CTNNA3 H3-3A HDGFL2 XRCC6

3.43e-081281109int:PARP2
InteractionVRK1 interactions

H1-10 SRSF6 H3-4 MECP2 HNRNPC PCF11 H3C1 FBXO28 MDC1 H3-3A XRCC6 TOP2B

3.81e-0827711012int:VRK1
InteractionNSD2 interactions

SRSF6 H3-4 MECP2 NECAP1 ZNF512B DDX46 H3C1 MDC1 H3-3A UHRF2 GOLGA3 XRCC6

3.97e-0827811012int:NSD2
InteractionDDX23 interactions

SRSF6 LRRC59 XPC GPATCH8 MECP2 ZNF512B PHF2 MSH6 DDX46 RECQL5 DDX23 H3-3A SCAF11 HDGFL2 TOP2B

5.36e-0848011015int:DDX23
InteractionH2AC14 interactions

H1-10 H3-5 H3-4 H3-7 H3C15 NECAP1 MSH6 H3C1 H3-3A

9.50e-081441109int:H2AC14
InteractionH1-4 interactions

H3-5 HIRIP3 LRRC59 GPATCH8 H3-4 H3-7 H3C15 HNRNPC ZNF512B TNRC18 H3C1 EFCAB12 POP1 MACF1 H3-3A SCAF11 TOP2B

9.70e-0865611017int:H1-4
InteractionH2AC4 interactions

H1-10 ACTR8 H3-5 HIRIP3 XPC H3-4 H3-7 H3C15 HNRNPC H3C1 POP1 DDX23 H3-3A SCAF11 XRCC6

1.06e-0750611015int:H2AC4
InteractionCHAMP1 interactions

H3-4 MECP2 AHDC1 H3C1 MDC1 H3-3A UHRF2 HDGFL2 XRCC6

1.20e-071481109int:CHAMP1
InteractionSET interactions

PPAN HIRIP3 H3-4 SP110 CDCA8 H3C15 MECP2 MEOX2 H3C1 DDX23 H3-3A XRCC6

1.35e-0731111012int:SET
InteractionH3-4 interactions

H1-10 H3-5 HIRIP3 H3-4 H3C15 AHDC1 PRDM2 PHF2 H3C1 ARHGEF1 POP1 AFF1 H3-3A CHD6

1.55e-0744811014int:H3-4
InteractionSSRP1 interactions

SRSF6 HIRIP3 XPC H3C15 MECP2 HNRNPC PCF11 PHF2 MSH6 H3C1 DDX23 H3-3A SCAF11 UHRF2 HDGFL2 XRCC6 TOP2B

1.79e-0768511017int:SSRP1
InteractionH3C15 interactions

H3-5 ANK2 TRO GPATCH8 H3-4 H3C15 MECP2 NECAP1 H3C1 H3-3A

2.02e-0720711010int:H3C15
InteractionPHF2 interactions

H3-4 MECP2 PHF2 TOX3 DDX23 H3-3A XRCC6

2.29e-07781107int:PHF2
InteractionATRX interactions

ANK2 HIRIP3 CDCA8 MECP2 ZNF512B DDX46 H3C1 H3-3A ANO7 UHRF2 XRCC6

2.41e-0726711011int:ATRX
InteractionMACROH2A2 interactions

H3-5 CGAS XPC H3-7 H3C15 MECP2 NECAP1 H3C1 HDGFL2 XRCC6

2.41e-0721111010int:MACROH2A2
InteractionNUMA1 interactions

H1-10 LRRC59 H3C15 PRDM2 NECAP1 H3C1 ARHGEF1 FBXO28 MDC1 MACF1 H3-3A UHRF2 XRCC6 TOP2B

2.70e-0746911014int:NUMA1
InteractionNSD1 interactions

H3-4 MECP2 THRA H3C1 MDC1 AFF1 H3-3A XRCC6

2.89e-071191108int:NSD1
InteractionMLLT1 interactions

H3-4 SP110 H3C1 BTK DDX23 AFF1 HDGFL2 TOP2B

3.73e-071231108int:MLLT1
InteractionCBX1 interactions

H3-4 SP110 CDCA8 H3C15 MECP2 AHDC1 H3C1 H3-3A HDGFL2 XRCC6 TOP2B

5.11e-0728811011int:CBX1
InteractionMEN1 interactions

H1-10 ACTR8 PPAN SRSF6 XPC MED1 H3-4 AHDC1 HNRNPC ZNF512B PCF11 DDX46 H3C1 ZNF608 MDC1 POP1 DDX23 H3-3A SCAF11 TOP2B

6.66e-07102911020int:MEN1
InteractionCDK11B interactions

IRF2BP2 SRSF6 HIRIP3 GPATCH8 MECP2 H3-3A UHRF2 HDGFL2 XRCC6

7.28e-071831109int:CDK11B
InteractionSUPT16H interactions

H3-5 XPC MED1 H3C15 MECP2 MSH6 H3C1 DDX23 H3-3A ANO7 UHRF2 XRCC6 TOP2B

8.77e-0744211013int:SUPT16H
InteractionTHRAP3 interactions

SRSF6 LRRC59 MED1 H3C15 MECP2 HNRNPC THRA H3C1 MDC1 DDX23 H3-3A UHRF2 XRCC6

8.99e-0744311013int:THRAP3
InteractionH2BC9 interactions

H1-10 H3-5 HIRIP3 TRO GPATCH8 H3-4 H3-7 H3C15 TNRC18 H3C1 MDC1 H3-3A HDGFL2

9.70e-0744611013int:H2BC9
InteractionZNF330 interactions

H1-10 XPC GPATCH8 CDCA8 MECP2 HNRNPC MEOX2 ZNF512B PHF2 MSH6 RECQL5 XRCC6 TOP2B

9.70e-0744611013int:ZNF330
InteractionHMGA2 interactions

XPC CDCA8 H3-7 MECP2 ZNF512B H3C1 MDC1 XRCC6

1.00e-061401108int:HMGA2
InteractionASF1A interactions

IRF2BP2 H3-4 CDCA8 PRDM2 ZNF512B PHF2 H3C1 MDC1 H3-3A CHD6

1.10e-0624911010int:ASF1A
InteractionPRC1 interactions

H1-10 ACTR8 PPAN H3-5 SRSF6 CGAS CDCA8 H3C15 MECP2 HNRNPC DDX46 H3C1 BTK MDC1 POP1 DDX23 XRCC6 TOP2B PDZD2

1.23e-0697311019int:PRC1
InteractionRAD18 interactions

H1-10 HIRIP3 XPC SP110 H3C15 H3C1 POP1 DDX23 H3-3A SCAF11 CTNNA1 HDGFL2 TOP2B

1.27e-0645711013int:RAD18
InteractionZNF512B interactions

XPC MECP2 CRX MEOX2 ZNF512B H3C1 DDX23 H3-3A XRCC6

1.29e-061961109int:ZNF512B
InteractionMACROH2A1 interactions

VCX2 SRSF6 HIRIP3 CGAS XPC H3-4 MECP2 NECAP1 MSH6 H3C1 H3-3A HDGFL2 XRCC6

1.30e-0645811013int:MACROH2A1
InteractionMECP2 interactions

SRSF6 LRRC59 XPC GPATCH8 MED1 H3C15 MECP2 AHDC1 HNRNPC ZNF512B PCF11 PHF2 MSH6 DDX46 H3C1 POP1 DDX23 MACF1 H3-3A CHD6 XRCC6 TOP2B

1.46e-06128711022int:MECP2
InteractionNUP43 interactions

H1-10 XPC GPATCH8 CDCA8 MECP2 AHDC1 PRDM2 PHF2 ZNF608 RECQL5 MDC1 TOX3 CHD6 TOP2B PDZD2

1.54e-0662511015int:NUP43
InteractionCHD2 interactions

CGAS MECP2 MEOX2 DDX23 H3-3A UHRF2

1.60e-06661106int:CHD2
InteractionSRPK2 interactions

PPAN SRSF6 HIRIP3 GPATCH8 HNRNPC PNMA8B PCF11 DDX46 EFCAB12 RECQL5 MDC1 POP1 DDX23 MACF1 SCAF11 TOP2B

1.73e-0671711016int:SRPK2
InteractionSNRNP40 interactions

SRSF6 XPC GPATCH8 BCL9 MECP2 AHDC1 HNRNPC ZNF608 RECQL5 MDC1 POP1 DDX23 SCAF11 HDGFL2 TOP2B

1.95e-0663711015int:SNRNP40
InteractionH2BC5 interactions

PPAN H3-5 XPC H3-4 H3-7 H3C15 NECAP1 MSH6 TNRC18 H3C1 H3-3A

1.99e-0633111011int:H2BC5
InteractionTOP2B interactions

H3-5 XPC MECP2 NECAP1 H3C1 DDX23 H3-3A UHRF2 XRCC6 TOP2B

2.00e-0626611010int:TOP2B
InteractionSUZ12 interactions

H1-10 ACTR8 SRSF6 CGAS H3-4 AHDC1 NECAP1 ZNF512B PHF2 H3C1 DDX23 H3-3A SCAF11 CTNNA1 UHRF2

2.23e-0664411015int:SUZ12
InteractionCIT interactions

H1-10 PPAN H3-5 SRSF6 CGAS LRRC59 MED1 CDCA8 H3C15 HNRNPC PHF2 MSH6 DDX46 MDC1 POP1 DDX23 MACF1 SCAF11 CTNNA1 UHRF2 HDGFL2 XRCC6 TOP2B

2.88e-06145011023int:CIT
InteractionAFF4 interactions

SP110 MECP2 H3C1 DDX23 AFF1 H3-3A XRCC6

3.21e-061151107int:AFF4
InteractionCUL7 interactions

H1-10 PPAN H3-5 SRSF6 LRRC59 SP110 H3C15 HNRNPC MSH6 DDX46 MDC1 DDX23 MACF1 CTNNA1 GOLGA3 XRCC6 TOP2B

3.23e-0684511017int:CUL7
InteractionH2AC13 interactions

H3-5 H3-4 H3C15 HNRNPC H3C1 H3-3A

3.42e-06751106int:H2AC13
InteractionPHF3 interactions

H3-4 H3C1 MDC1 DDX23 H3-3A UHRF2 XRCC6

3.81e-061181107int:PHF3
InteractionH2AC12 interactions

H1-10 H3-5 H3-4 H3-7 H3C15 H3C1 H3-3A

3.81e-061181107int:H2AC12
InteractionBRD2 interactions

H1-10 ACTR8 MED1 MECP2 PHF2 H3C1 VANGL1 MDC1 DDX23 H3-3A HDGFL2 TOP2B

3.98e-0642911012int:BRD2
InteractionCSNK2A1 interactions

PPAN HIRIP3 LRRC59 MECP2 HNRNPC MEOX1 MEOX2 MSH6 FBXO28 MDC1 POP1 MACF1 H3-3A CTNNA1 OCLN HDGFL2 XRCC6 BRMS1

4.06e-0695611018int:CSNK2A1
InteractionMYH10 interactions

XPC H3C15 MECP2 HNRNPC ZNF512B MSH6 H3C1 DDX23 GOLGA3 XRCC6 TOP2B

4.35e-0635911011int:MYH10
InteractionH1-3 interactions

H1-10 H3-5 H3-4 H3-7 H3C15 NECAP1 TNRC18 H3C1 POP1 H3-3A

4.44e-0629111010int:H1-3
InteractionDHX8 interactions

SRSF6 GPATCH8 MECP2 HNRNPC PCF11 DDX46 DDX23 H3-3A SCAF11 XRCC6

4.58e-0629211010int:DHX8
InteractionDNAJC8 interactions

H1-10 SRSF6 ZNF512B DDX46 H3C1 POP1 C1orf52 HDGFL2 TOP2B

4.80e-062301109int:DNAJC8
InteractionCBX2 interactions

DIS3L2 H3-4 MEOX2 H3C1 MDC1 H3-3A UHRF2

5.89e-061261107int:CBX2
InteractionTRRAP interactions

IRF2BP2 H3-5 SRSF6 HIRIP3 PPFIA3 MED1 H3-4 NUDT13 MECP2 ZNF512B H3C1 MDC1 DDX23 H3-3A CHD6 XRCC6

5.97e-0679011016int:TRRAP
InteractionC1orf174 interactions

XPC H3-7 MECP2 MEOX2 H3C1

6.28e-06481105int:C1orf174
InteractionNCL interactions

H1-10 PPAN H3-5 H3-4 H3C15 MECP2 NECAP1 MSH6 RECQL5 MDC1 DDX23 H3-3A UHRF2 HDGFL2 XRCC6 TOP2B

6.77e-0679811016int:NCL
InteractionUSF1 interactions

KIF21B PCF11 H3C1 H3-3A XRCC6 TOP2B

7.10e-06851106int:USF1
InteractionGATAD1 interactions

SAP30L GPATCH8 H3-4 ZNF512B TNRC18 H3-3A BRMS1

7.62e-061311107int:GATAD1
InteractionOBSL1 interactions

H1-10 PPAN H3-5 SRSF6 LRRC59 CDCA8 H3C15 HNRNPC DDX46 MDC1 POP1 DDX23 MACF1 CTNNA1 GOLGA3 XRCC6 TOP2B

7.67e-0690211017int:OBSL1
InteractionDOT1L interactions

H1-10 PPAN SRSF6 LRRC59 XPC H3-4 AHDC1 ZNF512B PCF11 DDX46 MDC1 POP1 AFF1 H3-3A SCAF11 TOP2B

7.80e-0680711016int:DOT1L
InteractionCSNK2B interactions

EPS8 PPAN SRSF6 HIRIP3 LRRC59 XPC SP110 MECP2 PHF2 H3-3A OCLN HDGFL2 TOP2B NOTCH3

7.80e-0662511014int:CSNK2B
InteractionKMT2A interactions

ACTR8 SRSF6 H3-4 H3C15 H3C1 ZNF608 AFF1 H3-3A UHRF2 XRCC6

8.66e-0631411010int:KMT2A
InteractionLOC102724334 interactions

H3-5 HIRIP3 H3-4 H3-7 H3C15 H3C1 H3-3A

8.84e-061341107int:LOC102724334
InteractionDNAJC17 interactions

HNRNPC MEOX2 PCF11 H3C1 C1orf52 DDX23 HDGFL2

8.84e-061341107int:DNAJC17
InteractionEHMT2 interactions

HIRIP3 H3-4 H3C15 AHDC1 CRX ZNF512B H3C1 CTNNA3 H3-3A UHRF2

8.90e-0631511010int:EHMT2
InteractionSETD2 interactions

SRSF6 H3-4 SP110 MECP2 H3C1 MDC1 DDX23

9.28e-061351107int:SETD2
InteractionRBM5 interactions

SRSF6 CGAS MED1 MECP2 MEOX1 MEOX2 DDX23

9.28e-061351107int:RBM5
InteractionDNMT1 interactions

TRO H3-4 MECP2 MSH6 H3C1 TOX3 H3-3A UHRF2 XRCC6

1.07e-052541109int:DNMT1
InteractionHMGB3 interactions

CGAS MECP2 MEOX1 MEOX2 H3C1 H3-3A

1.12e-05921106int:HMGB3
InteractionCEBPA interactions

IRF2BP2 MED1 BCL9 SP110 MECP2 AHDC1 HNRNPC PRDM2 PCF11 PHF2 MSH6 TNRC18 C1orf52 DDX23 MACF1 H3-3A UHRF2 HDGFL2 XRCC6 TOP2B

1.19e-05124511020int:CEBPA
InteractionH2BC4 interactions

H1-10 TRO H3-4 H3C15 TNRC18 H3C1 H3-3A XRCC6 TOP2B

1.25e-052591109int:H2BC4
InteractionBPTF interactions

SRSF6 H3-4 MECP2 ZNF512B H3C1 H3-3A UHRF2 XRCC6

1.26e-051971108int:BPTF
InteractionREXO4 interactions

PPAN SRSF6 H3C15 MECP2 H3C1 POP1 DDX23 H3-3A XRCC6

1.33e-052611109int:REXO4
InteractionDPF3 interactions

H3-5 H3-4 CRX H3C1 H3-3A HDGFL2

1.35e-05951106int:DPF3
InteractionADNP interactions

H3-4 MECP2 AHDC1 H3C1 H3-3A UHRF2 HDGFL2 XRCC6

1.36e-051991108int:ADNP
InteractionTAF15 interactions

SRSF6 H3-4 MECP2 HNRNPC DDX46 H3C1 DDX23 ANO7 SCAF11 XRCC6 TOP2B

1.45e-0540811011int:TAF15
InteractionCHD3 interactions

H1-10 SRSF6 LRRC59 HNRNPC ZNF512B MSH6 DDX46 H3C1 DDX23 H3-3A SCAF11 CHD6 UHRF2 XRCC6 TOP2B

1.55e-0575711015int:CHD3
InteractionH1-2 interactions

H1-10 PPAN H3-5 SRSF6 ANK2 H3-4 H3-7 H3C15 NECAP1 H3C1 EFCAB12 POP1 H3-3A SP140

1.59e-0566611014int:H1-2
InteractionKDM1B interactions

H3-4 MECP2 H3C1 MDC1 H3-3A

1.61e-05581105int:KDM1B
InteractionCENPC interactions

SRSF6 CGAS H3C1 MDC1 DDX23 H3-3A

1.61e-05981106int:CENPC
InteractionBAZ1B interactions

H3-5 CGAS NECAP1 H3C1 H3-3A UHRF2 XRCC6 TOP2B

1.63e-052041108int:BAZ1B
InteractionH2AC18 interactions

H3-5 H3-4 H3C15 NECAP1 TNRC18 H3C1 H3-3A

1.69e-051481107int:H2AC18
InteractionSMARCA5 interactions

PPAN CGAS MECP2 HNRNPC NECAP1 ZNF512B H3C1 H3-3A UHRF2 GOLGA3 XRCC6

1.70e-0541511011int:SMARCA5
InteractionNASP interactions

H3-5 H3-4 H3-7 H3C15 H3C1 MACF1 H3-3A XRCC6

1.81e-052071108int:NASP
InteractionLIG3 interactions

MECP2 THRA H3C1 MDC1 DDX23 H3-3A UHRF2 XRCC6

1.81e-052071108int:LIG3
GeneFamilyHistones

H1-10 H3-5 H3-4 H3-7 H3C15 H3C1 H3-3A

5.66e-07116767864
GeneFamilyVariable charge X/Y family

VCX2 VCX3A VCX

1.41e-066763368
GeneFamilyPHD finger proteins

SP110 PHF2 UHRF2 SP140

5.60e-049076488
CoexpressionPUJANA_ATM_PCC_NETWORK

KIF21B SRSF6 ARHGEF18 POU4F1 XPC POU6F1 MED1 SP110 HNRNPC PRDM2 PCF11 IFNG MSH6 DDX46 THRA ARHGEF1 BTK SCAF11 ALOX5 TOP2B SP140

3.00e-07139411021M9585
CoexpressionGSE19512_NAUTRAL_VS_INDUCED_TREG_UP

POU4F1 CRX MEOX2 THRA BTK TOX3 RAB40C PDZD2

1.88e-061971108M8361
CoexpressionGSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_DN

CDKN1C EPS8 ARHGEF18 XPC FAM13A BTK AFF1 MACF1

1.88e-061971108M9916
CoexpressionTRAVAGLINI_LUNG_PERICYTE_CELL

LAMC3 NOTCH3 FOXF1 FOXF2 PLCE1 PDZD2

8.79e-061141106M41678
CoexpressionFOURATI_BLOOD_TWINRIX_AGE_25_83YO_RESPONDERS_VS_POOR_RESPONDERS_0DY_DN

VCX3A CGAS SP110 CDCA8 H3C15 TNRC18 PDE12 THRA AFF1 TRIM50 CTNNA1 VCX PLCE1

1.52e-0574611013M40863
CoexpressionGSE8515_IL1_VS_IL6_4H_STIM_MAC_DN

CDKN1C TRO PCF11 MAGI2 IGHMBP2 FOXF1 CCDC144A

1.83e-051941107M5767
CoexpressionSCHERER_PBMC_YF_VAX_AGE_18_40YO_4_TO_7DY_UP

CDKN1C PPAN H3-4 SP110 HNRNPC PHF2 H3C1 H3-3A NOTCH3

1.98e-053561109M41052
CoexpressionGSE43863_TFH_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_UP

CDKN1C SRSF6 WSB2 LRRC59 IFNG DDX46 AFF1

2.22e-052001107M9770
CoexpressionGSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN

ACTR8 DCUN1D4 PHF2 FBXO28 MACF1 GOLGA3

7.58e-051671106M361
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPS8 NHSL2 LAMC3 CTNNA3 NOTCH3 FOXF2 PLCE1 PDZD2

2.22e-081841128327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 ATP10A MEOX2 SORBS3 CTNNA3 NOTCH3 PLCE1

3.31e-071771127a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 ATP10A MEOX2 SORBS3 CTNNA3 NOTCH3 PLCE1

3.31e-0717711273645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 LAMC3 ATP10A SORBS3 CTNNA3 NOTCH3 PLCE1

4.15e-071831127667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPS8 LAMC3 CTNNA3 NOTCH3 FOXF2 PLCE1 PDZD2

4.30e-071841127689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

ACTR8 MED1 BCL9 VANGL1 AFF1 SCAF11 OCLN

5.94e-071931127abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPS8 HIRIP3 CGAS CDCA8 ADRA2A H3C1

2.59e-061541126e3a8a1e63ab345de62bd2e5e54342b00f04ae422
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPS8 LAMC3 CTNNA3 NOTCH3 FOXF2 PLCE1

2.79e-0615611266365b69ede98bc866e996bc52736b00401aacf6f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPS8 LAMC3 NOTCH3 FOXF2 PLCE1 PDZD2

2.89e-061571126bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 ATP10A SORBS3 CTNNA3 NOTCH3 PLCE1

3.85e-0616511264f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 ATP10A SORBS3 CTNNA3 NOTCH3 PLCE1

3.85e-061651126cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ATP10A MEOX1 SORBS3 OCLN FOXF1 FOXF2

3.99e-06166112627af6c906cff1d40d134f0386db7708869691121
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDKN1C ANK2 GPR179 NOTCH3 FOXF2 PDZD2

5.06e-061731126f9d6e892d66f9b94e4d5beb9f5dec9b606bc868a
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDKN1C ANK2 GPR179 NOTCH3 FOXF2 PDZD2

5.06e-061731126cbd65dd5b01cc959e3ccbc89330ddd0122296ea3
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

H1-10 TRO CDCA8 CTNNA3 NOTCH3 PLCE1

5.23e-06174112641eb0a214a8b4015a26311f77061c8147144f0e7
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDKN1C PPFIA3 GPR179 NOTCH3 FOXF2 PDZD2

5.40e-0617511262a53d4f140d5ab096efe8118d8aa351db7838b49
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDKN1C PPFIA3 GPR179 NOTCH3 FOXF2 PDZD2

5.40e-061751126fb91a45763e4c48d993094a13088ffc19f1e2574
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDKN1C LAMC3 NOTCH3 FOXF1 FOXF2 PLCE1

5.77e-061771126452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPS8 LAMC3 CTNNA3 NOTCH3 PLCE1 PDZD2

6.98e-0618311268a799807fbf24456a9811e0c64068187940a2f71
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDKN1C TRO GPR179 NOTCH3 FOXF2 PDZD2

7.20e-06184112655dde9c4eebac2a33788c1ff1d8fe312d150fad4
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDKN1C TRO GPR179 NOTCH3 FOXF2 PDZD2

7.20e-0618411267128a2be291544d3df3ed6c80f21ddda8437dcba
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDKN1C TRO GPR179 NOTCH3 FOXF2 PDZD2

7.20e-061841126d14238f7b0b55a4c8d7040bea854bd221a66ac30
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes-Pericyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 H3-5 LAMC3 NOTCH3 FOXF2 PLCE1

7.43e-0618511260e26a71fea526ebfe3b2d1c8d0d6d9b70282bbe9
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes-Pericyte-Peri_L1-6_MUSTN1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 H3-5 LAMC3 NOTCH3 FOXF2 PLCE1

7.43e-061851126b3320b794b22e654a33f28b575c9f00023baf5f0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 ATP10A SORBS3 CTNNA3 NOTCH3 PLCE1

7.90e-06187112648bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 ATP10A SORBS3 CTNNA3 NOTCH3 PLCE1

7.90e-061871126958402fcc78f4c7a7d13d659d776f3817137975f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 ATP10A SORBS3 CTNNA3 NOTCH3 PLCE1

8.39e-061891126fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 ATP10A SORBS3 CTNNA3 NOTCH3 PLCE1

8.65e-0619011265681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

EPS8 LAMC3 CTNNA3 NOTCH3 PLCE1 PDZD2

9.18e-06192112655f95454399fd533df75db06584eaa48d6ee3830
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EPS8 LAMC3 CTNNA3 NOTCH3 PLCE1 PDZD2

9.18e-0619211265000440dc1ed17e7474d340921bdff945646f27e
ToppCellfacs-Thymus-nan-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP10A PHF2 MSH6 AFF1 XRCC6 TOP2B

1.00e-05195112679114b3c78cc15c413bb58f0673e7215b784a9b6
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

EPS8 LAMC3 CTNNA3 NOTCH3 PLCE1 PDZD2

1.06e-05197112644cd1ece3633a31e8c9b667cd3cbc2749c06f478
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EPS8 MEOX2 ADRA2A SORBS3 CTNNA3 NOTCH3

1.09e-051981126b7e900fc0a1b3fa5e47dcc36ce6b0c3ce6bf9739
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EPS8 LAMC3 CTNNA3 NOTCH3 PLCE1 PDZD2

1.09e-05198112676d46950c11cb4708866db0da54ce00d5c0adab8
ToppCelldistal-3-mesenchymal-Pericyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EPS8 LAMC3 NOTCH3 FOXF1 FOXF2 PLCE1

1.16e-052001126911db29f254bb697610e720ba78816e2c7f57933
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

LAMC3 NOTCH3 FOXF1 FOXF2 PLCE1 PDZD2

1.16e-0520011260c648941447c738caf62f2d71e296d6cca492c8b
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

EPS8 LAMC3 NOTCH3 FOXF2 PLCE1 PDZD2

1.16e-052001126d70bad979299615fcba707ba21296020918705e6
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

EPS8 LAMC3 NOTCH3 FOXF2 PLCE1 PDZD2

1.16e-05200112638c21ec379005f688df33aea65237a063c476c2e
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAMC3 NOTCH3 FOXF1 FOXF2 PLCE1 PDZD2

1.16e-052001126522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LAMC3 NOTCH3 FOXF1 FOXF2 PLCE1 PDZD2

1.16e-05200112694f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-GC_B_(II)|lymph-node_spleen / Manually curated celltypes from each tissue

QRICH2 ZNF512B MSH6 ZNF608 CCDC144A

4.13e-0515211254f690aed23338687bdefc47e8a2f3d1fdb2b6447
ToppCellfacs-BAT-Fat-24m-Lymphocytic-NK_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF18 IFNG H3C1 RECQL5 HDGFL2

4.53e-051551125550e7e7e52829244ead829e5be010bfdc71e2ba5
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTR8 POU6F1 ATP10A IFNG IGHMBP2

5.27e-05160112555f599df6e3b7a5a505df4b094c834281311d94a
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTR8 POU6F1 ATP10A IFNG IGHMBP2

5.27e-051601125296e53e1e0786346d38db2d4188b9a1c0430627b
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

ATP10A MEOX2 NOTCH3 FOXF1 PLCE1

5.43e-05161112547b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellfacs-Lung-Endomucin_-18m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF18 MSH6 H3C1 BTK SP140

5.59e-051621125e81dec1db8e5a808d96e58410c91961e5d065c94
ToppCellfacs-Lung-Endomucin_-18m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF18 MSH6 H3C1 BTK SP140

5.59e-051621125d19b469f64c9064cfb82dadb6c8135e28949a02a
ToppCellfacs-Lung-Endomucin_-18m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF18 MSH6 H3C1 BTK SP140

5.59e-05162112510c2aa047f33f48e4abe676236bbdb593079dd1d
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA8 H3C1 BTK ANO7 SP140

6.10e-051651125953c8242a81a39ade63ac8e5b34fe58575771746
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN1C ANK2 PPFIA3 NOTCH3 PDZD2

6.83e-0516911252d23b4cee060f8adddc430c1c10d4e25205b4af6
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN1C ANK2 PPFIA3 NOTCH3 PDZD2

6.83e-051691125ecaf08e8e0b54d1c97a02bc1f65409fd43d68227
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN1C ANK2 PPFIA3 NOTCH3 PDZD2

6.83e-051691125ad6af6609acf158cb79e45ee7ca9af332be3c40c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

EPS8 ZNF608 TOX3 TRIM50 OCLN

7.03e-051701125269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

EPS8 ATP10A MEOX2 NOTCH3 PLCE1

7.23e-051711125e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDKN1C MEOX1 NOTCH3 FOXF2 PDZD2

8.28e-051761125e2b59a904c5c8f9c88e1e63788e9b6485f22edd0
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDKN1C MEOX1 NOTCH3 FOXF2 PDZD2

8.28e-051761125f931192e3cc65414e2245354f443473696cc7ce8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 ATP10A CTNNA3 NOTCH3 PLCE1

8.50e-0517711254943d040eee0f9dceaddc7498171281d170e271f
ToppCelldroplet-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN1C MEOX1 NOTCH3 FOXF2 PDZD2

8.50e-05177112565709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 ATP10A CTNNA3 NOTCH3 PLCE1

8.50e-0517711253f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN1C MEOX1 NOTCH3 FOXF2 PDZD2

8.50e-0517711258684d47a547e2a06496f15e8da0200ecddc431e0
ToppCellMid-temporal_gyrus_(MTG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIF21B NHSL2 ANKRD6 CCDC144A PDZD2

8.73e-051781125ad187db4c40b9078d54dd915c143e0172b2f47b8
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CDKN1C EPS8 ZNF608 CTNNA3 OCLN

8.96e-051791125815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDKN1C MEOX1 NOTCH3 FOXF2 PDZD2

8.96e-051791125f5bb4d3a27d56698473219970e764084096cc582
ToppCellfacs-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN1C GPR179 NOTCH3 FOXF2 PDZD2

8.96e-0517911257078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDKN1C MEOX1 NOTCH3 FOXF2 PDZD2

8.96e-051791125fa03ec3cc0132f977b4cb28e7b23789732375183
ToppCellfacs-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN1C GPR179 NOTCH3 FOXF2 PDZD2

8.96e-051791125d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN1C MEOX1 NOTCH3 FOXF2 PDZD2

9.20e-0518011250153667e44fdbc3c0d444dcb023069925a2b69a2
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN1C MEOX1 NOTCH3 FOXF2 PDZD2

9.20e-05180112540a28b410f46215d6d7cf8a02a18078eb046b5b0
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI2 ZNF608 TOX3 OCLN NOTCH3

9.20e-051801125b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellRA-07._Pericyte|RA / Chamber and Cluster_Paper

EPS8 ATP10A MEOX2 NOTCH3 PDZD2

9.44e-0518111258dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCellBAL-Control-cDC_8|Control / Compartment, Disease Groups and Clusters

ZDHHC8 ATP10A H3C1 RECQL5 CCDC144A

9.44e-051811125f370161afef2ec827a7b194c06abb9ac1a507cbb
ToppCellRA-07._Pericyte|World / Chamber and Cluster_Paper

EPS8 ATP10A MEOX2 NOTCH3 PDZD2

9.69e-0518211252075efeae633550fb2eb026d0dfd741c8252482e
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF608 MACF1 SCAF11 TOP2B SP140

9.69e-051821125eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF608 MACF1 SCAF11 TOP2B SP140

9.94e-05183112528cbf909424f3be4491d49832f0aca0386560814
ToppCellLV-07._Pericyte|World / Chamber and Cluster_Paper

EPS8 MEOX2 NOTCH3 PLCE1 PDZD2

9.94e-051831125273db6a3b00a93ca852498471187b642b5368185
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF608 MACF1 SCAF11 TOP2B SP140

9.94e-0518311253fa608aa6b119869ec3280dc388dfee57160e63a
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF608 DDX23 MACF1 SCAF11 TOP2B

1.02e-0418411251154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMC3 CTNNA3 NOTCH3 FOXF2 PLCE1

1.02e-041841125102b6f621a5b551e622f97b12d787c080b052a72
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDKN1C EPS8 NOTCH3 FOXF2 PDZD2

1.02e-04184112523c24ab5786af33d605bc445d06117b9da6c6331
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 LAMC3 ATP10A SORBS3 NOTCH3

1.05e-0418511257092436b4db90289516ed130ade596e3021cffaf
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDKN1C ADRA2A NOTCH3 FOXF2 PDZD2

1.05e-041851125a6cd90f8f30c7bdf66958cf403e73c193aa32f5e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPS8 ANKRD6 ZNF608 TOX3 OCLN

1.05e-04185112598b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPS8 LAMC3 MEOX2 CTNNA3 NOTCH3

1.05e-04185112535d39a1d04c871edcfb749653538dc5fd0054281
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 LAMC3 ATP10A SORBS3 NOTCH3

1.05e-041851125a8ca7819066d5297ef6966e7f3e2c9f8a7673fdc
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDKN1C ADRA2A NOTCH3 FOXF2 PDZD2

1.05e-0418511255053f932e2adfcf4d6faaecff2999ac53d8d7aa5
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDKN1C GPR179 NOTCH3 FOXF2 PDZD2

1.05e-041851125b1e84228c95be8ccf7c3c1afb66b71ffb93cf61e
ToppCellLV-07._Pericyte|LV / Chamber and Cluster_Paper

EPS8 MEOX2 NOTCH3 PLCE1 PDZD2

1.05e-041851125acb38eba871ec72f2a8136a33b87d33b8c85465d
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMC3 NOTCH3 FOXF2 PLCE1 PDZD2

1.07e-041861125888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellRV-07._Pericyte|RV / Chamber and Cluster_Paper

EPS8 MEOX2 NOTCH3 PLCE1 PDZD2

1.07e-041861125c533b264fbe12bc35467486fc7fbde24ba968fe1
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

MAGI2 ZNF608 TOX3 OCLN NOTCH3

1.10e-041871125ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 ATP10A CTNNA3 NOTCH3 PLCE1

1.10e-041871125ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellfacs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIRIP3 ZNF512B FAM13A NOTCH3 PLCE1

1.10e-041871125f1e9877d859369b862d4a559ec9ab9be74a67a96
ToppCellfacs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIRIP3 ZNF512B FAM13A NOTCH3 PLCE1

1.10e-0418711253ffbd50b49059dcd3e23c5ac01901e4352142446
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 ATP10A CTNNA3 NOTCH3 PLCE1

1.10e-041871125530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMC3 NOTCH3 FOXF1 FOXF2 PLCE1

1.13e-041881125ee151792c7ac9afe820f1a281c6dab383799f358
ToppCellwk_20-22-Hematologic_Lymphocytic-B-small_pre-B-II_cell|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

H1-10 BTK H3-3A UHRF2 TOP2B

1.19e-041901125f49ceda3622cf079cffde9c9a9e3d0380c571d39
ToppCellFetal_29-31_weeks-Immune-B_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SP110 PRDM2 BTK ALOX5 SP140

1.19e-041901125424550418c1bd4eb070cf3c41cf09fa9d89aef37
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF608 BTK MACF1 SCAF11 SP140

1.19e-041901125ee7b60cdf93c695ea2d59a170ca8cf4dc93e7eb2
ToppCellFetal_29-31_weeks-Immune-B_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SP110 PRDM2 BTK ALOX5 SP140

1.22e-04191112584452125d1b5b76974e3f9126f611eff16d45c25
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMC3 NOTCH3 FOXF1 FOXF2 PLCE1

1.22e-0419111251626b23a57429f835fddc052e3c57f63a4e5b8bb
DrugAzaguanine-8 [134-58-7]; Down 200; 26.2uM; PC3; HT_HG-U133A

SAP30L XPC CDCA8 ZNF512B PCF11 FAM13A VANGL1 AFF1

3.00e-0618111181791_DN
Drug(1)-Nipecotic acid [498-95-3]; Down 200; 31uM; HL60; HT_HG-U133A

SAP30L ANKRD6 MECP2 LMF2 PDE12 RECQL5 SP140 BRMS1

5.41e-0619611183121_DN
DrugClofilium tosylate [92953-10-1]; Up 200; 7.8uM; MCF7; HT_HG-U133A

CDKN1C KIF21B LAMC3 ATP10A LMF2 RECQL5 RAB40C FOXF2

5.62e-0619711183187_UP
Drughydroxyurea

XPC CDCA8 H3-7 IFNG MSH6 RECQL5 MDC1 H3-3A ALOX5 XRCC6 TOP2B

9.51e-0643611111CID000003657
DiseaseEncephalopathies

LAMC3 IFNG NOTCH3

1.24e-04271063C0085584
DiseaseRespiratory Syncytial Virus Infections

IFNG PDE12

1.27e-0451062C0035235
Diseasecholangiocarcinoma, sclerosing cholangitis

SP110 SP140

1.27e-0451062EFO_0004268, EFO_0005221
DiseaseMalignant neoplasm of breast

ANK2 SP110 CRX IFNG MSH6 LMF2 BTK POP1 TOX3 AFF1 MACF1 OCLN NOTCH3

1.27e-04107410613C0006142
Diseasemosquito bite reaction itch intensity measurement, mosquito bite reaction size measurement

BNIP5 HNRNPC PCF11 PHF2 MAGI2 VANGL1 SORBS3

1.87e-043281067EFO_0008377, EFO_0008378
DiseaseGLIOMA SUSCEPTIBILITY 1

H3C1 H3-3A

1.90e-0461062C2750850
Diseaseresponse to anticonvulsant

ANK2 MAGI2 C1orf52 SP140

2.55e-04851064GO_0036277
Diseaselung cancer (implicated_via_orthology)

CDKN1C XPC

4.53e-0491062DOID:1324 (implicated_via_orthology)
DiseaseMYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO (finding)

SP110 IFNG

5.65e-04101062C1834752
DiseaseMycobacterium tuberculosis, susceptibility to

SP110 IFNG

5.65e-04101062cv:C1834752
DiseaseMYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO

SP110 IFNG

5.65e-04101062607948
DiseaseAdenocarcinoma of lung (disorder)

PPAN XPC MSH6 ALOX5 XRCC6

9.05e-042061065C0152013
Diseaseovarian neoplasm

LRRC59 BCL9 MSH6 ALOX5

1.41e-031341064C0919267
DiseaseCerebrovascular accident

ANK2 NOTCH3 FOXF2

1.46e-03621063C0038454
DiseaseMalignant neoplasm of ovary

LRRC59 BCL9 MSH6 ALOX5

1.53e-031371064C1140680
Diseasecolorectal cancer, inflammatory bowel disease

SP110 SP140

2.10e-03191062EFO_0003767, MONDO_0005575
DiseaseGlioblastoma

LRRC59 H3-3A NOTCH3

2.92e-03791063C0017636
DiseaseRenal glomerular disease

CDKN1C PLCE1

3.08e-03231062C0268731
DiseaseGlomerulopathy Assessment

CDKN1C PLCE1

3.08e-03231062C4521256
DiseaseMorbilliform Drug Reaction

IFNG ALOX5

3.08e-03231062C0406537
Diseasegeneralized anxiety disorder

LAMC3 CTNNA1

3.08e-03231062EFO_1001892
DiseaseDrug Eruptions

IFNG ALOX5

3.08e-03231062C0011609
DiseaseEpilepsy, Cryptogenic

CHRM1 MECP2 ADRA2A

3.25e-03821063C0086237
DiseaseAwakening Epilepsy

CHRM1 MECP2 ADRA2A

3.25e-03821063C0751111
DiseaseAura

CHRM1 MECP2 ADRA2A

3.25e-03821063C0236018
DiseaseGiant Cell Glioblastoma

LRRC59 H3-3A NOTCH3

3.48e-03841063C0334588

Protein segments in the cluster

PeptideGeneStartEntry
HKSPRNKDGRGSEKS

VANGL1

31

Q8TAA9
KRRPASGDDLSAKKS

DCUN1D4

66

Q92564
GNRRSDEPAKTKKGL

ARHGEF1

251

Q92888
GKECDSPKKRGRSRS

ARHGEF18

141

Q6ZSZ5
KAKRPLRGSSSQKAG

CXorf51A

51

A0A1B0GTR3
KAKRPLRGSSSQKAG

CXorf51B

51

P0DPH9
RNGSLKPGSSHRKTK

BTK

171

Q06187
AKATADRKSASKPIG

ACTR8

436

Q9H981
APGDTGVDKRDRKKS

CCDC144NL

101

Q6NUI1
QSSSKPGRGRRKKVD

AHDC1

1226

Q5TGY3
PAKSAGGCRNKAEKR

C1orf52

41

Q8N6N3
SPGDKKSKNRSTRGK

DIS3L2

31

Q8IYB7
FGPARKSGSRQKKSA

CGAS

51

Q8N884
RSQGPGKSKRTDKKT

EFCAB12

456

Q6NXP0
SRGLQRAPEKTKGKV

ATP10A

936

O60312
KKSGKSGPTRHRAQQ

ANKRD6

621

Q9Y2G4
GSKGNSLKRSKSIRP

RAB40C

251

Q96S21
RKDSSGTSKRKSQQP

QRICH2

1616

Q9H0J4
APAKGRAGRSKRTEQ

OCLN

381

Q16625
NRGKPEGSSKARKER

MEOX1

161

P50221
FNGSSQRRKRPKKSD

ANK2

16

Q01484
SKKRKAGASAGASQG

ANO7

676

Q6IWH7
NGGEKKRKRTSIAAP

POU4F1

351

Q01851
GGPQGERKNRSSKKS

HIRIP3

376

Q9BW71
AEPKVNRGKAGVKRS

HNRNPC

86

P07910
ATRGRKNRSSGKTPE

MDC1

1391

Q14676
GATPSAEGKRKRNKS

MAGI2

206

Q86UL8
SQKKRGEARGKSEPI

GPR179

1286

Q6PRD1
ANQAPKSKSGSRPRK

LRRC59

221

Q96AG4
QTARKSTGGKAPRKQ

H3-3A

6

P84243
STGGKAPRKQLATKA

H3-3A

11

P84243
KAAPGAAGSRRADKK

H1-10

146

Q92522
AKLTGPGDKDRRNKR

PPFIA3

806

O75145
RTQSIQGKGKGKRSS

CDCA8

151

Q53HL2
QGKGKGKRSSRANTV

CDCA8

156

Q53HL2
QTARKSTGGKAPRKQ

H3-7

6

Q5TEC6
STGGKAPRKQLATKA

H3-7

11

Q5TEC6
RKKNKSSAPADSERG

GPATCH8

716

Q9UKJ3
QTARKSTGGKAPRKQ

H3-5

6

Q6NXT2
STGGKAPRKQLATKA

H3-5

11

Q6NXT2
AAKKSRKSRPNASGG

PDE12

91

Q6L8Q7
KNSPAGKSGKVRLRD

PDZD2

126

O15018
GTRPARKKFQKKGAS

KIF21B

891

O75037
PGLKAAQSGSKKSRR

NOTCH3

2051

Q9UM47
AQSGSKKSRRPPGKA

NOTCH3

2056

Q9UM47
FVGGEPSKKRKRRTS

POU6F1

226

Q14863
KTNRADPKKSASRPG

MACF1

3426

O94854
QTARKSTGGKAPRKQ

H3-4

6

Q16695
PAEAEKRSGGKRKSD

MEOX2

156

P50222
QTARKSTGGKAPRKQ

H3C1

6

P68431
STGGKAPRKQLATKA

H3C1

11

P68431
KDRKRSSLSPGRGKD

DDX23

101

Q9BUQ8
SSLSPGRGKDFKSRK

DDX23

106

Q9BUQ8
GNGSLKRKSSRKETP

MSH6

306

P52701
TFGCAGERSKPKRQK

FAM13A

456

O94988
RGAAKTRKEPKGEAS

GOLGA3

1376

Q08378
RSGQPTKKNVAGSKR

NUDT13

171

Q86X67
GGRKKKKAPSASDSD

HDGFL2

221

Q7Z4V5
KQGTKPGRSSTRKRS

PCF11

466

O94913
KREKRQKPGRASSDG

POP1

916

Q99575
PQNPSSRKKGRSKRA

CTNNA3

41

Q9UI47
KKHTSKEPRRAGAAG

BNIP5

446

P0C671
NTNSKGPSNKKRGRS

CTNNA1

41

P35221
FAKRKRSAPEKSSGD

CDKN1C

276

P49918
AARTKSRKASKEQGP

CHD6

176

Q8TD26
NGAKGKGKRERSISA

BCL9

91

O00512
SGSGQNEESPRKRKK

FBXO28

336

Q9NVF7
APGDTGVDKRDRKKS

CCDC144B

101

Q3MJ40
SSPNTVKRPTKKGRD

CHRM1

321

P11229
AELSPAAKTGKRKRS

IFNG

141

P01579
DSKGGKQKRRPDALR

EPS8

186

Q12929
SPGNKSKKTENRSRS

DDX46

106

Q7L014
APGDTGVDKRDRKKS

CCDC144A

101

A2RUR9
QSPSPKNESARGRKK

SCAF11

831

Q99590
GSKAVARTARKRKPS

IRF2BP2

346

Q7Z5L9
QAKARPAKRKAGTSP

CRX

111

O43186
KPGKRSRTPSNDGKS

MED1

991

Q15648
KEPLGSTNSEAKKRR

PRDM2

626

Q13029
KKRGRKPGSVVAAAA

MECP2

266

P51608
GGAKKASSGLRRPEK

FOXF2

86

Q12947
SGPSKAKKTNAGIRR

FOXF1

31

Q12946
PAKATEAGKRKSSSQ

VCX3A

11

Q9NNX9
KRKGEAATRAKPSAA

TATDN2

201

Q93075
KPGRNARVKKESGSS

PHF2

746

O75151
GRGAKKRKASGSENE

TOP2B

1541

Q02880
GEKRRPASQKDSGAA

LMF2

671

Q9BU23
RKSSGFPKSVKSREQ

ALOX5

521

P09917
QKKGSKATPRSRPSA

NHSL2

1181

Q5HYW2
GKERKSRKSIFGNNP

PLCE1

1691

Q9P212
QAPTGSKAARGKKAR

PNMA8B

611

Q9ULN7
QTARKSTGGKAPRKQ

H3C15

6

Q71DI3
STGGKAPRKQLATKA

H3C15

11

Q71DI3
SRSRSPKENGKGDIK

SRSF6

276

Q13247
RHKKKSLPGGTASSR

SP110

291

Q9HB58
KARAAVSPQKRKSDG

BRMS1

231

Q9HCU9
RGKGKARASQVKPGD

ADRA2A

331

P08913
KKPVKASARAGSRTS

AFF1

606

P51825
KTKGRPRAAASNEPK

AFF1

646

P51825
SGGSSLAKGRASKKQ

RECQL5

736

O94762
GKTPLKNGSSCKRTN

UHRF2

161

Q96PU4
AQAGAKSRPKKREGV

TNRC18

2741

O15417
TKRKHDNEGSGSKRP

XRCC6

541

P12956
PAKATEAGKRKSSSQ

VCX2

11

Q9H322
KGKKAASRGPNSVSE

TRO

301

Q12816
FPKTKDKSQGAQARR

PPAN

436

Q9NQ55
RQGRKKPAGKSLASE

IGHMBP2

691

P38935
TSEKINKRSGPKRGR

SSX8P

146

Q7RTT4
NKRKRKTSDDGGDSP

SAP30L

86

Q9HAJ7
ERPCKSSKGNKRGRT

ZNF556

111

Q9HAH1
GGSPARREEKKRKAA

SORBS3

371

O60504
RAIGEKRAAPDSGKK

TOX3

226

O15405
PAKATEAGKRKSSSQ

VCX

11

Q9H320
NKAPRATGRNSGKKR

ZNF512B

331

Q96KM6
KPGKSQSSRGAKRDK

ZNF608

191

Q9ULD9
SDNGLKAGLGRSKSK

ZDHHC8

286

Q9ULC8
KAGLGRSKSKGSLDR

ZDHHC8

291

Q9ULC8
KRGKPGTRFTQSDRA

SP140

551

Q13342
SPDGKRKRKNGQCSL

THRA

21

P10827
RSSKNETKGRGSPKE

WSB2

71

Q9NYS7
TFAKGTCRPSAKGKR

XPC

371

Q01831
NKGGRKKRSKPSSSE

XPC

386

Q01831
GKDLSGNKTRSCKAP

TMIGD3

186

P0DMS9
IKGTASRKGKLNRSP

TRIM50

366

Q86XT4
NAAPLSSSAKKKGRE

LAMC3

1386

Q9Y6N6
ITNKKGGASKPRTAR

NECAP1

166

Q8NC96