Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	actin binding	ESPN FMNL3 EVL WASH3P WASL WIPF1 FMN1 MICAL2 TPRN WASHC1 ENAH WIPF3 WHAMM FHDC1 DIAPH3 SHTN1 LMOD2 FMNL2 WASF1 WIPF2 JMY FMNL1 VASP MYO16 PXK CAP2	6.90e-21	479	93	26	GO:0003779
GeneOntologyMolecularFunction	cytoskeletal protein binding	ESPN FMNL3 EVL WASH3P WASL ATF5 WIPF1 FMN1 MICAL2 TPRN WASHC1 ENAH WIPF3 WHAMM FHDC1 DIAPH3 SHTN1 LMOD2 FMNL2 WASF1 WIPF2 JMY FMNL1 VASP MYO16 PXK CAP2 HTT	5.71e-14	1099	93	28	GO:0008092
GeneOntologyMolecularFunction	profilin binding	EVL WIPF1 PCLO ENAH FMNL1 VASP HTT	6.33e-14	13	93	7	GO:0005522
GeneOntologyMolecularFunction	SH3 domain binding	ESPN EVL WIPF1 FMN1 ENAH WIPF3 VASP	4.73e-06	143	93	7	GO:0017124
GeneOntologyMolecularFunction	tubulin binding	WASH3P WASL ATF5 FMN1 WASHC1 WIPF3 WHAMM FHDC1 DIAPH3 JMY HTT	4.86e-06	428	93	11	GO:0015631
GeneOntologyMolecularFunction	Arp2/3 complex binding	WHAMM WASF1 JMY	5.24e-05	16	93	3	GO:0071933
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	BPTF HOXB4 ZNF526 MYPOP SALL2 ZNF628 ZFHX4 ZNF341 ZIC5 ZBTB4 GLIS3 SKOR1 DMRTB1 ZFHX3 ZBTB12 KDM6B FOXK1	5.45e-05	1244	93	17	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	BPTF HOXB4 ZNF526 MYPOP SALL2 ZNF628 ZFHX4 ZNF341 ZIC5 ZBTB4 GLIS3 SKOR1 DMRTB1 ZFHX3 ZBTB12 KDM6B FOXK1	7.12e-05	1271	93	17	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	BPTF HOXB4 ZNF526 MYPOP SALL2 ATF5 ZNF628 ZFHX4 ZNF341 ZIC5 ZBTB4 GLIS3 SKOR1 DMRTB1 ZFHX3 ZBTB12 KDM6B FOXK1	1.19e-04	1459	93	18	GO:0000977
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	SETD1B KMT2B	5.90e-04	8	93	2	GO:0140945
GeneOntologyMolecularFunction	phosphatidylinositol 3-kinase inhibitor activity	WASH3P WASHC1	5.90e-04	8	93	2	GO:0141039
GeneOntologyMolecularFunction	actin filament binding	ESPN FMNL3 SHTN1 FMNL2 FMNL1 MYO16	6.76e-04	227	93	6	GO:0051015
GeneOntologyMolecularFunction	gamma-tubulin binding	WASH3P WASHC1 WIPF3	7.33e-04	38	93	3	GO:0043015
GeneOntologyMolecularFunction	small GTPase binding	FMNL3 RANBP9 WHAMM DIAPH3 FMNL2 WASF1 FMNL1	7.55e-04	321	93	7	GO:0031267
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	HOXB4 ZNF526 MYPOP SALL2 ATF5 ZNF628 ZFHX4 ZNF341 ZIC5 ZBTB4 GLIS3 SKOR1 DMRTB1 ZFHX3 ZBTB12 FOXK1	7.63e-04	1412	93	16	GO:0000981
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	SETD1B KMT2B	9.42e-04	10	93	2	GO:0140999
GeneOntologyMolecularFunction	GTPase binding	FMNL3 RANBP9 WHAMM DIAPH3 FMNL2 WASF1 FMNL1	1.47e-03	360	93	7	GO:0051020
GeneOntologyMolecularFunction	alpha-tubulin binding	WASH3P WASHC1 WIPF3	1.83e-03	52	93	3	GO:0043014
GeneOntologyMolecularFunction	phosphatidylinositol 3-kinase regulator activity	WASH3P WASHC1	3.13e-03	18	93	2	GO:0035014
GeneOntologyMolecularFunction	microtubule binding	WASL FMN1 WHAMM FHDC1 DIAPH3 JMY	3.18e-03	308	93	6	GO:0008017
GeneOntologyMolecularFunction	GTPase activating protein binding	FMNL3 FMNL1	3.49e-03	19	93	2	GO:0032794
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	MYPOP ZBTB4 GLIS3 ZFHX3 ZBTB12 FOXK1	3.84e-03	320	93	6	GO:0001227
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	SETD1B KMT2B	3.86e-03	20	93	2	GO:0042800
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	MYPOP ZBTB4 GLIS3 ZFHX3 ZBTB12 FOXK1	4.20e-03	326	93	6	GO:0001217
GeneOntologyBiologicalProcess	actin cytoskeleton organization	ESPN FMNL3 EVL WASH3P WASL GRID2IP WIPF1 FMN1 MICAL2 PCLO WASHC1 ENAH WIPF3 ADGRB1 PCDH15 WHAMM FHDC1 DIAPH3 SHTN1 LMOD2 FMNL2 WASF1 JMY FMNL1 VASP CAP2	5.52e-16	803	91	26	GO:0030036
GeneOntologyBiologicalProcess	actin filament-based process	ESPN FMNL3 EVL WASH3P WASL PDE4D GRID2IP WIPF1 FMN1 MICAL2 PCLO WASHC1 ENAH WIPF3 ADGRB1 PCDH15 WHAMM FHDC1 DIAPH3 SHTN1 LMOD2 FMNL2 WASF1 JMY FMNL1 VASP CAP2	1.21e-15	912	91	27	GO:0030029
GeneOntologyBiologicalProcess	actin nucleation	EVL WASH3P WASL FMN1 WASHC1 WIPF3 WHAMM DIAPH3 LMOD2 WASF1 JMY	4.86e-15	65	91	11	GO:0045010
GeneOntologyBiologicalProcess	actin filament organization	ESPN EVL WASH3P WASL WIPF1 FMN1 MICAL2 WASHC1 ENAH WIPF3 PCDH15 WHAMM FHDC1 DIAPH3 SHTN1 LMOD2 WASF1 JMY VASP CAP2	6.26e-14	509	91	20	GO:0007015
GeneOntologyBiologicalProcess	actin polymerization or depolymerization	EVL WASH3P WASL WIPF1 FMN1 MICAL2 WASHC1 ENAH FHDC1 DIAPH3 LMOD2 WASF1 VASP	1.67e-11	222	91	13	GO:0008154
GeneOntologyBiologicalProcess	supramolecular fiber organization	ESPN EVL WASH3P WASL WIPF1 FMN1 MICAL2 WASHC1 ENAH WIPF3 RANBP9 PCDH15 WHAMM FHDC1 DIAPH3 SHTN1 LMOD2 WASF1 JMY VASP CAP2 HTT	1.21e-10	957	91	22	GO:0097435
GeneOntologyBiologicalProcess	actin filament polymerization	EVL WASH3P WASL FMN1 WASHC1 FHDC1 DIAPH3 LMOD2 WASF1 VASP	1.17e-08	190	91	10	GO:0030041
GeneOntologyBiologicalProcess	Arp2/3 complex-mediated actin nucleation	WASH3P WASHC1 WIPF3 WHAMM WASF1 JMY	5.79e-08	47	91	6	GO:0034314
GeneOntologyBiologicalProcess	protein polymerization	EVL WASH3P WASL FMN1 WASHC1 RANBP9 FHDC1 DIAPH3 LMOD2 WASF1 VASP	2.54e-07	334	91	11	GO:0051258
GeneOntologyBiologicalProcess	regulation of actin nucleation	WASH3P FMN1 WASHC1 WHAMM WASF1	9.89e-07	41	91	5	GO:0051125
GeneOntologyBiologicalProcess	cell morphogenesis	FMNL3 EVL WASL PPP3CB RAPH1 TPRN ENAH ADGRB1 PCDH15 SHTN1 FMNL2 WASF1 FMNL1 VASP MYO16 SEMA4G CAP2	1.61e-05	1194	91	17	GO:0000902
GeneOntologyBiologicalProcess	positive regulation of actin nucleation	FMN1 WHAMM WASF1	2.92e-05	14	91	3	GO:0051127
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	TRERF1 TRIM66 BPTF HOXB4 MYPOP SALL2 ATF5 ZNF827 ZBTB4 GLIS3 SKOR1 ZFTA ZFHX3 ZBTB12 ZNF318 FASLG SF1 FOXK1	3.38e-05	1399	91	18	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	TRERF1 TRIM66 BPTF HOXB4 MYPOP SALL2 ATF5 ZNF827 ZBTB4 GLIS3 SKOR1 ZFTA ZFHX3 ZBTB12 ZNF318 FASLG SF1 FOXK1	3.86e-05	1413	91	18	GO:1902679
GeneOntologyBiologicalProcess	regulation of actin filament organization	EVL WASH3P FMN1 WASHC1 WHAMM LMOD2 WASF1 VASP	5.45e-05	300	91	8	GO:0110053
GeneOntologyBiologicalProcess	regulation of actin filament polymerization	EVL WASH3P FMN1 WASHC1 LMOD2 VASP	6.67e-05	156	91	6	GO:0030833
GeneOntologyBiologicalProcess	regulation of actin polymerization or depolymerization	EVL WASH3P FMN1 WASHC1 LMOD2 VASP	1.34e-04	177	91	6	GO:0008064
GeneOntologyBiologicalProcess	positive regulation of actin filament polymerization	EVL FMN1 LMOD2 VASP	1.34e-04	59	91	4	GO:0030838
GeneOntologyBiologicalProcess	regulation of actin filament-based process	EVL WASH3P PDE4D FMN1 WASHC1 WHAMM LMOD2 WASF1 VASP	1.36e-04	438	91	9	GO:0032970
GeneOntologyBiologicalProcess	regulation of supramolecular fiber organization	EVL WASH3P FMN1 WASHC1 WHAMM DIAPH3 LMOD2 WASF1 VASP	1.36e-04	438	91	9	GO:1902903
GeneOntologyBiologicalProcess	regulation of actin filament length	EVL WASH3P FMN1 WASHC1 LMOD2 VASP	1.47e-04	180	91	6	GO:0030832
GeneOntologyBiologicalProcess	ovulation	PDE4D KMT2B INHBB	1.57e-04	24	91	3	GO:0030728
GeneOntologyBiologicalProcess	presynaptic actin cytoskeleton organization	PCLO CAP2	1.91e-04	5	91	2	GO:0099140
GeneOntologyBiologicalProcess	positive regulation of organelle organization	EVL PPP3CB FMN1 NAF1 WHAMM LMOD2 WASF1 VASP MAP3K4 HTT	2.19e-04	574	91	10	GO:0010638
GeneOntologyBiologicalProcess	positive regulation of supramolecular fiber organization	EVL FMN1 WHAMM LMOD2 WASF1 VASP	2.33e-04	196	91	6	GO:1902905
GeneOntologyBiologicalProcess	regulation of cytoskeleton organization	ESPN EVL WASH3P FMN1 WASHC1 WHAMM DIAPH3 LMOD2 WASF1 VASP	2.35e-04	579	91	10	GO:0051493
GeneOntologyBiologicalProcess	presynaptic cytoskeleton organization	PCLO CAP2	2.85e-04	6	91	2	GO:0099187
GeneOntologyBiologicalProcess	positive regulation of cholesterol import	WASH3P WASHC1	2.85e-04	6	91	2	GO:1904109
GeneOntologyBiologicalProcess	positive regulation of cellular component organization	ESPN EVL WASL PPP3CB FMN1 NAF1 WASHC1 ADGRB1 WHAMM SHTN1 FASLG LMOD2 WASF1 VASP MAP3K4 HTT	2.90e-04	1366	91	16	GO:0051130
GeneOntologyBiologicalProcess	positive regulation of cytoskeleton organization	EVL FMN1 WHAMM LMOD2 WASF1 VASP	2.96e-04	205	91	6	GO:0051495
GeneOntologyBiologicalProcess	regulation of actin cytoskeleton organization	EVL WASH3P FMN1 WASHC1 WHAMM LMOD2 WASF1 VASP	2.97e-04	384	91	8	GO:0032956
GeneOntologyBiologicalProcess	regulation of Arp2/3 complex-mediated actin nucleation	WASH3P WASHC1 WASF1	3.41e-04	31	91	3	GO:0034315
GeneOntologyBiologicalProcess	actin polymerization-dependent cell motility	ENAH JMY	3.99e-04	7	91	2	GO:0070358
GeneOntologyBiologicalProcess	vocal learning	NRXN2 HTT	3.99e-04	7	91	2	GO:0042297
GeneOntologyBiologicalProcess	imitative learning	NRXN2 HTT	3.99e-04	7	91	2	GO:0098596
GeneOntologyBiologicalProcess	protein depolymerization	EVL MICAL2 DIAPH3 LMOD2 HTT	4.44e-04	144	91	5	GO:0051261
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	EVL WASL PPP3CB RAPH1 TPRN ENAH ADGRB1 PCDH15 SHTN1 VASP SEMA4G	4.48e-04	748	91	11	GO:0048667
GeneOntologyBiologicalProcess	regulation of protein polymerization	EVL WASH3P FMN1 WASHC1 LMOD2 VASP	5.58e-04	231	91	6	GO:0032271
GeneOntologyBiologicalProcess	actin filament-based movement	EVL WASL PDE4D WIPF1 SHTN1	5.86e-04	153	91	5	GO:0030048
GeneOntologyBiologicalProcess	regulation of cellular component size	EVL WASH3P FMN1 PCLO WASHC1 SHTN1 LMOD2 VASP	5.91e-04	426	91	8	GO:0032535
GeneOntologyBiologicalProcess	regulation of cholesterol import	WASH3P WASHC1	6.79e-04	9	91	2	GO:0060620
GeneOntologyBiologicalProcess	observational learning	NRXN2 HTT	6.79e-04	9	91	2	GO:0098597
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection assembly	ESPN FMNL3 EVL WASL WASHC1 PCDH15 WHAMM FHDC1 SHTN1 HTT	7.37e-04	670	91	10	GO:0120031
GeneOntologyBiologicalProcess	neuron projection morphogenesis	EVL WASL PPP3CB RAPH1 ENAH ADGRB1 SHTN1 WASF1 VASP MYO16 SEMA4G	7.98e-04	802	91	11	GO:0048812
GeneOntologyBiologicalProcess	polar body extrusion after meiotic divisions	WASH3P WASHC1	8.47e-04	10	91	2	GO:0040038
GeneOntologyBiologicalProcess	cell projection assembly	ESPN FMNL3 EVL WASL WASHC1 PCDH15 WHAMM FHDC1 SHTN1 HTT	8.72e-04	685	91	10	GO:0030031
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	EVL WASL PPP3CB RAPH1 ENAH ADGRB1 SHTN1 WASF1 VASP MYO16 SEMA4G	9.47e-04	819	91	11	GO:0120039
GeneOntologyBiologicalProcess	oocyte development	WASH3P KMT2B INHBB WASHC1	9.69e-04	99	91	4	GO:0048599
GeneOntologyBiologicalProcess	cell projection morphogenesis	EVL WASL PPP3CB RAPH1 ENAH ADGRB1 SHTN1 WASF1 VASP MYO16 SEMA4G	1.01e-03	826	91	11	GO:0048858
GeneOntologyBiologicalProcess	cortical actin cytoskeleton organization	FMNL3 FMNL2 FMNL1	1.03e-03	45	91	3	GO:0030866
GeneOntologyBiologicalProcess	learned vocalization behavior or vocal learning	NRXN2 HTT	1.03e-03	11	91	2	GO:0098598
GeneOntologyBiologicalProcess	positive regulation of cellular component biogenesis	ESPN EVL WASL FMN1 WASHC1 ADGRB1 LMOD2 VASP HTT	1.07e-03	582	91	9	GO:0044089
GeneOntologyBiologicalProcess	positive regulation of protein polymerization	EVL FMN1 LMOD2 VASP	1.08e-03	102	91	4	GO:0032273
GeneOntologyBiologicalProcess	oocyte differentiation	WASH3P KMT2B INHBB WASHC1	1.12e-03	103	91	4	GO:0009994
GeneOntologyBiologicalProcess	meiotic cytokinesis	WASH3P WASHC1	1.45e-03	13	91	2	GO:0033206
GeneOntologyCellularComponent	lamellipodium	EVL WASH3P WASL RAPH1 WASHC1 ENAH SHTN1 WASF1 VASP	7.24e-07	230	91	9	GO:0030027
GeneOntologyCellularComponent	actin cytoskeleton	ESPN EVL WASL WIPF1 FMN1 MICAL2 ENAH FHDC1 DIAPH3 LMOD2 WASF1 VASP MYO16	1.24e-06	576	91	13	GO:0015629
GeneOntologyCellularComponent	actin-based cell projection	ESPN WASH3P RAPH1 TPRN WASHC1 ENAH PCDH15 SHTN1 VASP	3.46e-06	278	91	9	GO:0098858
GeneOntologyCellularComponent	actin filament	ESPN WIPF1 FMN1 MICAL2 FHDC1 DIAPH3 LMOD2	3.48e-06	146	91	7	GO:0005884
GeneOntologyCellularComponent	cell leading edge	EVL WASH3P WASL WIPF1 RAPH1 WASHC1 ENAH SHTN1 WASF1 JMY VASP	1.11e-05	500	91	11	GO:0031252
GeneOntologyCellularComponent	filopodium	WASH3P RAPH1 WASHC1 ENAH SHTN1 VASP	1.63e-05	123	91	6	GO:0030175
GeneOntologyCellularComponent	WASH complex	WASH3P WASHC1 WIPF3	3.50e-05	15	91	3	GO:0071203
GeneOntologyCellularComponent	histone methyltransferase complex	SETD1B KMT2B PELP1 KDM6B	3.23e-04	75	91	4	GO:0035097
GeneOntologyCellularComponent	stereocilium bundle	ESPN TPRN PCDH15 DIAPH3	3.93e-04	79	91	4	GO:0032421
GeneOntologyCellularComponent	methyltransferase complex	SETD1B KMT2B PELP1 KDM6B	1.28e-03	108	91	4	GO:0034708
GeneOntologyCellularComponent	autophagosome	WASH3P WASHC1 JMY HTT	1.82e-03	119	91	4	GO:0005776
Domain	WH2	ESPN WASL WIPF1 WASHC1 WIPF3 WHAMM WASH2P LMOD2 WASF1 WIPF2 JMY PXK	1.64e-22	24	89	12	PS51082
Domain	WH2_dom	ESPN WASL WIPF1 WIPF3 WHAMM WASH2P LMOD2 WASF1 WIPF2 JMY PXK	5.14e-21	21	89	11	IPR003124
Domain	WH2	ESPN WASL WIPF1 WIPF3 WASF1 WIPF2 JMY	1.47e-13	14	89	7	SM00246
Domain	FH2	FMNL3 GRID2IP FMN1 FHDC1 DIAPH3 FMNL2 FMNL1	2.74e-13	15	89	7	PS51444
Domain	FH2_Formin	FMNL3 GRID2IP FMN1 FHDC1 DIAPH3 FMNL2 FMNL1	2.74e-13	15	89	7	IPR015425
Domain	FH2	FMNL3 GRID2IP FMN1 FHDC1 DIAPH3 FMNL2 FMNL1	2.74e-13	15	89	7	PF02181
Domain	FH2	FMNL3 GRID2IP FMN1 FHDC1 DIAPH3 FMNL2 FMNL1	2.74e-13	15	89	7	SM00498
Domain	WH2	ESPN WASL WIPF1 WIPF3 WASF1 WIPF2 PXK	4.85e-13	16	89	7	PF02205
Domain	Drf_GBD	FMNL3 DIAPH3 FMNL2 FMNL1	5.96e-08	9	89	4	PF06371
Domain	FH3_dom	FMNL3 DIAPH3 FMNL2 FMNL1	5.96e-08	9	89	4	IPR010472
Domain	GTPase-bd	FMNL3 DIAPH3 FMNL2 FMNL1	5.96e-08	9	89	4	IPR010473
Domain	Drf_FH3	FMNL3 DIAPH3 FMNL2 FMNL1	5.96e-08	9	89	4	PF06367
Domain	Drf_FH3	FMNL3 DIAPH3 FMNL2 FMNL1	5.96e-08	9	89	4	SM01139
Domain	Drf_GBD	FMNL3 DIAPH3 FMNL2 FMNL1	5.96e-08	9	89	4	SM01140
Domain	VASP_tetra	EVL ENAH VASP	1.05e-07	3	89	3	IPR014885
Domain	VASP_tetra	EVL ENAH VASP	1.05e-07	3	89	3	PF08776
Domain	WH1	EVL WASL ENAH VASP	1.55e-07	11	89	4	SM00461
Domain	GBD/FH3_dom	FMNL3 DIAPH3 FMNL2 FMNL1	1.55e-07	11	89	4	IPR014768
Domain	WH1/EVH1_dom	EVL WASL ENAH VASP	1.55e-07	11	89	4	IPR000697
Domain	WH1	EVL WASL ENAH VASP	1.55e-07	11	89	4	PF00568
Domain	GBD_FH3	FMNL3 DIAPH3 FMNL2 FMNL1	1.55e-07	11	89	4	PS51232
Domain	WH1	EVL WASL ENAH VASP	3.33e-07	13	89	4	PS50229
Domain	DAD_dom	DIAPH3 FMNL2 FMNL1	5.76e-06	8	89	3	IPR014767
Domain	DAD	DIAPH3 FMNL2 FMNL1	5.76e-06	8	89	3	PS51231
Domain	WHAMM-JMY_N	WHAMM JMY	2.25e-05	2	89	2	PF15920
Domain	Vasodilator_phosphoprotein	EVL VASP	2.25e-05	2	89	2	IPR017354
Domain	JMY/WHAMM	WHAMM JMY	2.25e-05	2	89	2	IPR031738
Domain	JMY	WHAMM JMY	2.25e-05	2	89	2	PF15871
Domain	JMY/WHAMM_N	WHAMM JMY	2.25e-05	2	89	2	IPR031808
Domain	Inhibin_betaB	PRRG2 INHBB	2.25e-05	2	89	2	IPR000381
Domain	Znf_C2H2-like	TRERF1 ZNF526 SALL2 ZNF628 ZFHX4 ZNF827 ZNF341 ZIC5 ZBTB4 GLIS3 ZFTA ZFHX3 ZBTB12 ZNF318	2.28e-05	796	89	14	IPR015880
Domain	ZnF_C2H2	TRERF1 ZNF526 SALL2 ZNF628 ZFHX4 ZNF827 ZNF341 ZIC5 ZBTB4 GLIS3 ZFTA ZFHX3 ZBTB12 ZNF318	2.69e-05	808	89	14	SM00355
Domain	-	TRERF1 ZNF526 SALL2 ZNF628 ZFHX4 ZNF827 ZNF341 ZIC5 ZBTB4 GLIS3 ZFHX3 ZBTB12	8.86e-05	679	89	12	3.30.160.60
Domain	zf-C2H2	TRERF1 ZNF526 SALL2 ZNF628 ZFHX4 ZNF827 ZNF341 ZIC5 ZBTB4 GLIS3 ZFHX3 ZBTB12	1.07e-04	693	89	12	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	TRERF1 ZNF526 SALL2 ZNF628 ZFHX4 ZNF827 ZNF341 ZIC5 ZBTB4 GLIS3 ZFHX3 ZBTB12	1.09e-04	694	89	12	IPR013087
Domain	-	TRIM66 BPTF KMT2B USP51 ZNF341 PCLO RNF44 MARCHF11 MEX3C	2.87e-04	449	89	9	3.30.40.10
Domain	ZINC_FINGER_C2H2_2	TRERF1 ZNF526 SALL2 ZNF628 ZFHX4 ZNF827 ZNF341 ZIC5 ZBTB4 GLIS3 ZFHX3 ZBTB12	3.02e-04	775	89	12	PS50157
Domain	ZINC_FINGER_C2H2_1	TRERF1 ZNF526 SALL2 ZNF628 ZFHX4 ZNF827 ZNF341 ZIC5 ZBTB4 GLIS3 ZFHX3 ZBTB12	3.09e-04	777	89	12	PS00028
Domain	Znf_RING/FYVE/PHD	TRIM66 BPTF KMT2B USP51 ZNF341 PCLO RNF44 MARCHF11 MEX3C	3.38e-04	459	89	9	IPR013083
Domain	ZnF_U1	ZFHX4 ZFHX3 ZNF318	3.49e-04	29	89	3	SM00451
Domain	Znf_U1	ZFHX4 ZFHX3 ZNF318	3.49e-04	29	89	3	IPR003604
Domain	Znf_C2H2	TRERF1 ZNF526 SALL2 ZNF628 ZFHX4 ZNF827 ZNF341 ZIC5 ZBTB4 GLIS3 ZFHX3 ZBTB12	4.26e-04	805	89	12	IPR007087
Domain	Znf_FYVE_PHD	TRIM66 BPTF KMT2B PCLO ZBTB4	6.89e-04	147	89	5	IPR011011
Domain	ZF_PHD_2	TRIM66 BPTF KMT2B ASXL3	1.10e-03	95	89	4	PS50016
Domain	ZF_PHD_1	TRIM66 BPTF KMT2B ASXL3	1.15e-03	96	89	4	PS01359
Domain	ARM-type_fold	FMNL3 PELP1 DIAPH3 TRRAP FMNL2 FMNL1 HTT	1.18e-03	339	89	7	IPR016024
Domain	-	ANTXRL WASL	1.44e-03	12	89	2	3.90.810.10
Domain	OTU	VCPIP1 ALG13	1.69e-03	13	89	2	PF02338
Domain	OTU	VCPIP1 ALG13	2.26e-03	15	89	2	PS50802
Domain	OTU_dom	VCPIP1 ALG13	2.26e-03	15	89	2	IPR003323
Domain	Post-SET_dom	SETD1B KMT2B	2.58e-03	16	89	2	IPR003616
Domain	PostSET	SETD1B KMT2B	2.58e-03	16	89	2	SM00508
Domain	POST_SET	SETD1B KMT2B	2.58e-03	16	89	2	PS50868
Domain	-	EVL WASL IRS4 RAPH1 DGKK ENAH VASP	2.64e-03	391	89	7	2.30.29.30
Domain	PH_dom-like	EVL WASL IRS4 RAPH1 DGKK ENAH VASP	4.23e-03	426	89	7	IPR011993
Domain	CRIB_dom	ANTXRL WASL	4.45e-03	21	89	2	IPR000095
Domain	PHD	TRIM66 BPTF KMT2B	5.52e-03	75	89	3	PF00628
Pathway	REACTOME_CDC42_GTPASE_CYCLE	FMNL3 WASL WIPF1 WIPF3 DIAPH3 FMNL2 WIPF2 FMNL1	4.14e-07	155	63	8	M41808
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_WASPS_AND_WAVES	WASL WIPF1 WIPF3 WASF1 WIPF2	5.14e-07	36	63	5	M27549
Pathway	KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_EAE_TIR_TO_ACTIN_SIGNALING_PATHWAY	WASL WIPF1 WIPF3 WIPF2	8.25e-07	17	63	4	M47728
Pathway	REACTOME_RHO_GTPASE_EFFECTORS	FMNL3 EVL WASL WIPF1 WIPF3 DIAPH3 FMNL2 WASF1 WIPF2 FMNL1	1.51e-06	323	63	10	M27080
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_ACTIN_SIGNALING_PATHWAY	WASL WIPF1 WIPF3 WIPF2	2.05e-06	21	63	4	M47722
Pathway	REACTOME_RAC1_GTPASE_CYCLE	WASL WIPF1 WIPF3 DIAPH3 WASF1 WIPF2 FMNL1	1.72e-05	184	63	7	M41809
Pathway	REACTOME_RHO_GTPASE_EFFECTORS	FMNL3 EVL WIPF1 WIPF3 DIAPH3 FMNL2 WASF1 FMNL1	1.78e-05	257	63	8	MM14755
Pathway	REACTOME_RHO_GTPASE_CYCLE	FMNL3 WASL WIPF1 WIPF3 WHAMM DIAPH3 FMNL2 WASF1 WIPF2 FMNL1	2.79e-05	450	63	10	M27078
Pathway	REACTOME_SIGNALING_BY_ROBO_RECEPTORS	EVL ENAH VASP	9.19e-05	20	63	3	MM14974
Pathway	REACTOME_RHOJ_GTPASE_CYCLE	FMNL3 WASL DIAPH3 WIPF2	1.04e-04	55	63	4	M41815
Pathway	REACTOME_PARASITE_INFECTION	WASL WIPF1 WIPF3 WASF1 WIPF2	1.66e-04	116	63	5	M29843
Pathway	BIOCARTA_SALMONELLA_PATHWAY	WASL WASF1	1.95e-04	5	63	2	M16120
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	FMNL3 EVL WASL WIPF1 WIPF3 WHAMM DIAPH3 FMNL2 WASF1 WIPF2 FMNL1	3.09e-04	720	63	11	M41838
Pathway	REACTOME_SENSORY_PROCESSING_OF_SOUND	ESPN TPRN PCLO PCDH15	3.84e-04	77	63	4	M41822
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_FORMINS	FMNL3 EVL DIAPH3 FMNL2 FMNL1	3.98e-04	140	63	5	M27550
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_FORMINS	FMNL3 EVL DIAPH3 FMNL2 FMNL1	4.11e-04	141	63	5	MM15266
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	WASL WIPF1 WIPF3 WASF1 WIPF2	4.39e-04	143	63	5	M27107
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_WASPS_AND_WAVES	WIPF1 WIPF3 WASF1	4.61e-04	34	63	3	MM15265
Pathway	SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES	WASL WASF1 VASP	5.03e-04	35	63	3	M16801
Pathway	REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES	EVL ENAH VASP	6.93e-04	39	63	3	M16523
Pathway	BIOCARTA_ACTINY_PATHWAY	WASL WASF1	8.64e-04	10	63	2	MM1528
Pathway	BIOCARTA_ACTINY_PATHWAY	WASL WASF1	1.26e-03	12	63	2	M7825
Pathway	REACTOME_SENSORY_PROCESSING_OF_SOUND_BY_OUTER_HAIR_CELLS_OF_THE_COCHLEA	ESPN TPRN PCDH15	1.89e-03	55	63	3	M41823
Pubmed	Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton.	EVL WASL RAPH1 ENAH WIPF3 WASF1 WIPF2 VASP	5.46e-17	17	95	8	14506234
Pubmed	Expression of multiple formins in adult tissues and during developmental stages of mouse brain.	FMNL3 FMN1 FHDC1 DIAPH3 FMNL2 FMNL1	1.04e-12	14	95	6	26272686
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	WASL IRS4 KMT2B RAPH1 ENAH WIPF3 FNBP4 ZNF318 SHTN1 TRRAP WIPF2 VASP SF1 SF3B2 CAP2	8.57e-12	506	95	15	30890647
Pubmed	FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands.	FMNL3 KMT2B ENAH ZFHX3 SF1	3.41e-11	10	95	5	9171351
Pubmed	Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics.	EVL RAPH1 ENAH VASP	5.22e-11	4	95	4	15469845
Pubmed	Characterization of the murine orthologue of a novel human subtelomeric multigene family.	WASH3P WASH4P WASHC1 WASH2P	2.61e-10	5	95	4	11701968
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	EVL WASL WIPF1 ENAH WIPF2 FMNL1 VASP SF1 SF3B2	4.39e-10	154	95	9	16055720
Pubmed	Human subtelomeric WASH genes encode a new subclass of the WASP family.	WASH3P WASH4P WASHC1 WASH2P	7.80e-10	6	95	4	18159949
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TRERF1 PRR12 IRS4 SALL2 KMT2B ZFHX4 RAPH1 ZFHX3 ZNF318 DIAPH3 SHTN1 VCPIP1	1.73e-09	418	95	12	34709266
Pubmed	Mammalian Fat1 cadherin regulates actin dynamics and cell-cell contact.	WASL ENAH WASF1 VASP	6.51e-09	9	95	4	15148305
Pubmed	Functional proteomics mapping of a human signaling pathway.	FMNL3 KMT2B PELP1 ZNF341 PEG10 TPRN FNBP4 RANBP9 DIAPH3 FMNL2 FMNL1 CAP2 VCPIP1	8.45e-09	591	95	13	15231748
Pubmed	Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico.	FMNL3 FMNL2 FMNL1	1.97e-08	3	95	3	12684686
Pubmed	A Requirement for Mena, an Actin Regulator, in Local mRNA Translation in Developing Neurons.	EVL ENAH VASP	1.97e-08	3	95	3	28735747
Pubmed	Cell autonomous defects in cortical development revealed by two-color chimera analysis.	EVL ENAH VASP	1.97e-08	3	95	3	19386231
Pubmed	The WH1 and EVH1 domains of WASP and Ena/VASP family members bind distinct sequence motifs.	WASL WIPF1 WIPF3	1.97e-08	3	95	3	12372256
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	BPTF IRS4 KMT2B RAPH1 ENAH FNBP4 ZNF318 DIAPH3 SHTN1 TRRAP HTT VCPIP1	3.54e-08	549	95	12	38280479
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ESRP2 PRR12 NHSL1 SCAF1 HOXB4 SETD1B KMT2B ZNF628 ZNF827 ZNF341 ZBTB4 KDM6B TRRAP FOXK1 HTT C6orf132	5.08e-08	1105	95	16	35748872
Pubmed	Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains.	FMNL3 KMT2B FMN1 FNBP4	5.12e-08	14	95	4	8605874
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TRIM66 BPTF SCAF1 ZNF526 SALL2 ZFHX4 ZNF827 TPRN NAF1 RANBP9 ZFHX3 ZNF318 TRRAP FMNL2 FOXK1 ALG13	5.81e-08	1116	95	16	31753913
Pubmed	Ena/VASP is required for endothelial barrier function in vivo.	EVL ENAH VASP	7.88e-08	4	95	3	17998398
Pubmed	Biochemical analysis of the human ENA/VASP-family proteins, MENA, VASP and EVL, in homologous recombination.	EVL ENAH VASP	7.88e-08	4	95	3	21398369
Pubmed	Mena is required for neurulation and commissure formation.	EVL ENAH VASP	7.88e-08	4	95	3	10069337
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TRERF1 EVL BPTF SCAF1 KMT2B RAPH1 NAF1 FNBP4 ZNF318 TRRAP SF1 SF3B2 VCPIP1	1.94e-07	774	95	13	15302935
Pubmed	PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins.	RAPH1 ENAH VASP	1.97e-07	5	95	3	15642358
Pubmed	Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP.	EVL ENAH VASP	1.97e-07	5	95	3	16631741
Pubmed	Enteropathogenic Escherichia coli and vaccinia virus do not require the family of WASP-interacting proteins for pathogen-induced actin assembly.	WASL WIPF1 WIPF2	1.97e-07	5	95	3	22966049
Pubmed	c-Abl, Lamellipodin, and Ena/VASP proteins cooperate in dorsal ruffling of fibroblasts and axonal morphogenesis.	EVL RAPH1 VASP	1.97e-07	5	95	3	20417104
Pubmed	The state of the actin cytoskeleton determines its association with gephyrin: role of ena/VASP family members.	EVL ENAH VASP	1.97e-07	5	95	3	16376568
Pubmed	A requirement for filopodia extension toward Slit during Robo-mediated axon repulsion.	EVL ENAH VASP	1.97e-07	5	95	3	27091449
Pubmed	Spectrin interacts with EVL (Enabled/vasodilator-stimulated phosphoprotein-like protein), a protein involved in actin polymerization.	EVL ENAH VASP	1.97e-07	5	95	3	16336193
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TRIM66 WASL PPP3CB MICAL2 PEG10 ZBTB4 RANBP9 WHAMM R3HDM1 KDM6B SHTN1 FMNL2 SF1 SF3B2 CAP2 VCPIP1	3.89e-07	1285	95	16	35914814
Pubmed	Endophilin, Lamellipodin, and Mena cooperate to regulate F-actin-dependent EGF-receptor endocytosis.	RAPH1 ENAH VASP	3.93e-07	6	95	3	24076656
Pubmed	The E3 Ubiquitin Ligase TRIM9 Is a Filopodia Off Switch Required for Netrin-Dependent Axon Guidance.	EVL ENAH VASP	3.93e-07	6	95	3	26702829
Pubmed	Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.	WASL PDE4D WIPF1 FNBP4 FASLG WIPF2	6.36e-07	111	95	6	22558309
Pubmed	RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion.	EVL ENAH VASP	6.86e-07	7	95	3	15469846
Pubmed	Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton.	EVL ENAH VASP	6.86e-07	7	95	3	10747096
Pubmed	Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region.	WASH3P WASHC1 WASH2P	1.09e-06	8	95	3	10655549
Pubmed	Ena/VASP Is Required for neuritogenesis in the developing cortex.	EVL ENAH VASP	1.09e-06	8	95	3	17988629
Pubmed	Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor.	EVL ENAH VASP	1.09e-06	8	95	3	10892742
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	NHSL1 EVL PCLO ENAH WASF1 VASP MYO16	2.39e-06	218	95	7	33378226
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	NHSL1 RAPH1 FMN1 DIAPH3 SHTN1 FMNL2 WIPF2 VASP C6orf132 VCPIP1	3.47e-06	565	95	10	25468996
Pubmed	The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1.	FMN1 FNBP4 SF1	4.27e-06	12	95	3	11604498
Pubmed	Interaction network of human early embryonic transcription factors.	TRERF1 PRR12 BPTF KMT2B ZFHX4 ASXL3 ZFHX3 FOXK1	5.63e-06	351	95	8	38297188
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	RAPH1 ZNF318 DIAPH3 SHTN1 SF1 SF3B2 VCPIP1	6.87e-06	256	95	7	33397691
Pubmed	Male-specific sterility caused by the loss of CR16.	WASL WIPF3	7.38e-06	2	95	2	17573773
Pubmed	Structure of the N-WASP EVH1 domain-WIP complex: insight into the molecular basis of Wiskott-Aldrich Syndrome.	WASL WIPF1	7.38e-06	2	95	2	12437929
Pubmed	Cell type-dependent mechanisms for formin-mediated assembly of filopodia.	FMNL3 DIAPH3	7.38e-06	2	95	2	26446836
Pubmed	Ena/VASP proteins enhance actin polymerization in the presence of barbed end capping proteins.	EVL VASP	7.38e-06	2	95	2	15939738
Pubmed	Invadopodia proteins, cortactin, N-WASP and WIP differentially promote local invasiveness in ameloblastoma.	WASL WIPF1	7.38e-06	2	95	2	26752341
Pubmed	Ena/VASP Protein-Mediated Actin Polymerization Contributes to Naïve CD8+ T Cell Activation and Expansion by Promoting T Cell-APC Interactions In Vivo.	EVL VASP	7.38e-06	2	95	2	35757762
Pubmed	The mouse formin, FRLalpha, slows actin filament barbed end elongation, competes with capping protein, accelerates polymerization from monomers, and severs filaments.	FMN1 FMNL1	7.38e-06	2	95	2	14990563
Pubmed	WASH and the Arp2/3 complex regulate endosome shape and trafficking.	WASH3P WASHC1	7.38e-06	2	95	2	20175130
Pubmed	FMNL formins boost lamellipodial force generation.	FMNL3 FMNL2	7.38e-06	2	95	2	28327544
Pubmed	WIP and WICH/WIRE co-ordinately control invadopodium formation and maturation in human breast cancer cell invasion.	WIPF1 WIPF2	7.38e-06	2	95	2	27009365
Pubmed	A critical function for the actin cytoskeleton in targeted exocytosis of prefusion vesicles during myoblast fusion.	WASL WIPF1	7.38e-06	2	95	2	17419995
Pubmed	A strategy to identify protein-N-myristoylation-dependent phosphorylation reactions of cellular proteins by using Phos-tag SDS-PAGE.	FMNL3 FMNL2	7.38e-06	2	95	2	31751425
Pubmed	The mouse ZFH-4 protein contains four homeodomains and twenty-two zinc fingers.	ZFHX4 ZFHX3	7.38e-06	2	95	2	10873665
Pubmed	Genetic evidence that formins function within the nucleus.	FMN1 FNBP4	7.38e-06	2	95	2	8798555
Pubmed	Protein N-myristoylation is required for cellular morphological changes induced by two formin family proteins, FMNL2 and FMNL3.	FMNL3 FMNL2	7.38e-06	2	95	2	22790947
Pubmed	Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2.	FMN1 FMNL1	7.38e-06	2	95	2	16480715
Pubmed	ENA/VASP downregulation triggers cell death by impairing axonal maintenance in hippocampal neurons.	EVL ENAH	7.38e-06	2	95	2	20230896
Pubmed	Distribution, cellular localization, and postnatal development of VASP and Mena expression in mouse tissues.	ENAH VASP	7.38e-06	2	95	2	11810195
Pubmed	Critical roles for multiple formins during cardiac myofibril development and repair.	FMNL2 FMNL1	7.38e-06	2	95	2	24430873
Pubmed	Ena/VASP proteins contribute to Listeria monocytogenes pathogenesis by controlling temporal and spatial persistence of bacterial actin-based motility.	ENAH VASP	7.38e-06	2	95	2	12940993
Pubmed	Lamellipodin promotes invasive 3D cancer cell migration via regulated interactions with Ena/VASP and SCAR/WAVE.	WASF1 VASP	7.38e-06	2	95	2	26996666
Pubmed	Vasodilator-stimulated phosphoprotein restricts cell-to-cell spread of Shigella flexneri at the cell periphery.	EVL VASP	7.38e-06	2	95	2	26358985
Pubmed	WAVE binds Ena/VASP for enhanced Arp2/3 complex-based actin assembly.	WASF1 VASP	7.38e-06	2	95	2	25355952
Pubmed	Role of proteins of the Ena/VASP family in actin-based motility of Listeria monocytogenes.	EVL VASP	7.38e-06	2	95	2	10087267
Pubmed	Disruption of cardiac Ena-VASP protein localization in intercalated disks causes dilated cardiomyopathy.	ENAH VASP	7.38e-06	2	95	2	12933343
Pubmed	Ena/VASP proteins regulate activated T-cell trafficking by promoting diapedesis during transendothelial migration.	EVL VASP	7.38e-06	2	95	2	28320969
Pubmed	Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.	WASL IRS4 WIPF1 WIPF3 WIPF2	9.69e-06	103	95	5	21706016
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	PRR12 BPTF SCAF1 MYPOP KMT2B PELP1 ZIC5 FNBP4 ZNF318 TRRAP SF1 SF3B2 FOXK1 VCPIP1	1.11e-05	1294	95	14	30804502
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	TRERF1 BPTF MYPOP SALL2 ZIC5 PEG10 PCLO PCDH15	1.35e-05	396	95	8	26687479
Pubmed	The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development.	ZFHX4 ZFHX3 KDM6B	2.18e-05	20	95	3	35177643
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	SETD1B ASXL3 FOXK1	2.18e-05	20	95	3	29785026
Pubmed	Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases.	PDE4D PPP3CB	2.21e-05	3	95	2	23258544
Pubmed	N-WASP involvement in dorsal ruffle formation in mouse embryonic fibroblasts.	WASL WASF1	2.21e-05	3	95	2	17182853
Pubmed	An siRNA screen identifies RSK1 as a key modulator of lung cancer metastasis.	ENAH VASP	2.21e-05	3	95	2	21423205
Pubmed	Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice.	WASH3P WASHC1	2.21e-05	3	95	2	38086439
Pubmed	Waltzing with WASP.	WASL WIPF1	2.21e-05	3	95	2	10087612
Pubmed	VASP is a CXCR2-interacting protein that regulates CXCR2-mediated polarization and chemotaxis.	ENAH VASP	2.21e-05	3	95	2	19435808
Pubmed	The adaptor protein Nck interacts with Fas ligand: Guiding the death factor to the cytotoxic immunological synapse.	WASL FASLG	2.21e-05	3	95	2	16595635
Pubmed	Lamellipodin promotes actin assembly by clustering Ena/VASP proteins and tethering them to actin filaments.	RAPH1 VASP	2.21e-05	3	95	2	26295568
Pubmed	WIP provides an essential link between Nck and N-WASP during Arp2/3-dependent actin polymerization.	WASL WIPF1	2.21e-05	3	95	2	23707428
Pubmed	Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy.	ENAH VASP	2.21e-05	3	95	2	23937664
Pubmed	Characterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteins.	ENAH VASP	2.21e-05	3	95	2	10801818
Pubmed	WASH Regulates Glucose Homeostasis by Facilitating Glut2 Receptor Recycling in Pancreatic β-Cells.	WASH3P WASHC1	2.21e-05	3	95	2	30425062
Pubmed	Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo.	RAPH1 WASF1	2.21e-05	3	95	2	24247431
Pubmed	Telomere Length and Male Fertility.	NAF1 PXK	2.21e-05	3	95	2	33921254
Pubmed	The Cdc42 effector IRSp53 generates filopodia by coupling membrane protrusion with actin dynamics.	WASL ENAH	2.21e-05	3	95	2	18448434
Pubmed	Mechanistic differences in actin bundling activity of two mammalian formins, FRL1 and mDia2.	DIAPH3 FMNL1	2.21e-05	3	95	2	16556604
Pubmed	WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.	WASH3P WASHC1	2.21e-05	3	95	2	25225459
Pubmed	Loss of Scar/WAVE complex promotes N-WASP- and FAK-dependent invasion.	WASL WASF1	2.21e-05	3	95	2	23273897
Pubmed	Bi-modal regulation of a formin by srGAP2.	FMNL3 FMNL1	2.21e-05	3	95	2	21148482
Pubmed	WAVE2, N-WASP, and Mena facilitate cell invasion via phosphatidylinositol 3-kinase-dependent local accumulation of actin filaments.	WASL ENAH	2.21e-05	3	95	2	21769917
Pubmed	The filamentous actin cross-linking/bundling activity of mammalian formins.	DIAPH3 FMNL1	2.21e-05	3	95	2	18835565
Pubmed	Structural details of human tuba recruitment by InlC of Listeria monocytogenes elucidate bacterial cell-cell spreading.	WASL ENAH	2.21e-05	3	95	2	24332715
Pubmed	FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42.	FMNL3 FMNL2	2.21e-05	3	95	2	28852060
Pubmed	Human transcription factor protein interaction networks.	TRERF1 PRR12 BPTF IRS4 SALL2 KMT2B ZFHX4 PEG10 DGKK ZFHX3 ZNF318 R3HDM1 TRRAP FOXK1	3.33e-05	1429	95	14	35140242
Pubmed	A census of human transcription factors: function, expression and evolution.	TRERF1 HOXB4 MYPOP SALL2 ATF5 ZFHX4 ZBTB4 SKOR1 DMRTB1 ZFHX3 FOXK1	3.84e-05	908	95	11	19274049
Interaction	PRMT2 interactions	ESPN WASL SALL2 SETD1B USP51 ZNF341 DMRTB1 R3HDM1 KDM6B SHTN1 FASLG SF1 HTT VCPIP1	5.74e-18	91	93	14	int:PRMT2
Interaction	PFN1 interactions	NHSL1 EVL WASL MYPOP GRID2IP RAPH1 PCLO ENAH WIPF3 RANBP9 DIAPH3 SHTN1 FMNL2 WASF1 WIPF2 JMY FMNL1 VASP SF3B2 HTT C6orf132 VCPIP1 ALG13	7.97e-17	509	93	23	int:PFN1
Interaction	PRPF40A interactions	FMNL3 EVL WASL KMT2B WIPF1 PELP1 ZNF341 FMN1 ENAH FNBP4 ZFHX3 FASLG FMNL2 WASF1 FMNL1 VASP SF1 SF3B2 CAP2 HTT ALG13	9.40e-16	446	93	21	int:PRPF40A
Interaction	NCK2 interactions	NHSL1 WASL ZNF526 MYPOP WIPF1 RAPH1 ZNF341 WIPF3 ZBTB12 FASLG WASF1 WIPF2 VASP SF1	1.65e-11	262	93	14	int:NCK2
Interaction	ACTG1 interactions	EVL WASL WIPF1 ASXL3 WASHC1 ENAH WIPF3 WHAMM FMNL2 WASF1 WIPF2 VASP PXK CAP2 MAP3K4 HTT	1.87e-09	520	93	16	int:ACTG1
Interaction	PFN2 interactions	EVL MYPOP GRID2IP PCLO ENAH KDM6B WASF1 FMNL1 VASP HTT	3.24e-09	159	93	10	int:PFN2
Interaction	DNMBP interactions	EVL WASL RAPH1 ENAH WIPF3 FASLG WASF1 WIPF2 VASP	5.87e-09	124	93	9	int:DNMBP
Interaction	FHDC1 interactions	FMNL3 GRID2IP FMN1 FHDC1 DIAPH3	1.53e-08	18	93	5	int:FHDC1
Interaction	FMN1 interactions	FMNL3 FMN1 FHDC1 DIAPH3 FMNL1	5.91e-08	23	93	5	int:FMN1
Interaction	ACTB interactions	NHSL1 WASH3P WASL RAPH1 PEG10 WASHC1 ENAH WIPF3 DIAPH3 SHTN1 WASF1 WIPF2 JMY VASP PXK CAP2 MAP3K4 HTT C6orf132 VCPIP1	8.50e-08	1083	93	20	int:ACTB
Interaction	FMNL3 interactions	FMNL3 FMN1 FHDC1 DIAPH3 FMNL2 FMNL1	9.78e-08	49	93	6	int:FMNL3
Interaction	ACTC1 interactions	WASL IRS4 KMT2B WIPF1 RAPH1 ENAH WIPF3 FNBP4 ZNF318 SHTN1 TRRAP WIPF2 VASP SF1 SF3B2 CAP2	1.06e-07	694	93	16	int:ACTC1
Interaction	VASP interactions	NHSL1 EVL RAPH1 ENAH DMRTB1 JMY VASP SF3B2 FOXK1 C6orf132 ALG13	1.12e-07	294	93	11	int:VASP
Interaction	APBB1 interactions	EVL WASL WIPF1 ENAH FASLG WIPF2 VASP SF1 SF3B2	2.95e-07	195	93	9	int:APBB1
Interaction	BAIAP2 interactions	ESPN EVL WASL ENAH ADGRB1 FMNL2 WASF1 VASP C6orf132	3.81e-07	201	93	9	int:BAIAP2
Interaction	BCHE interactions	WASL NAF1 ENAH DIAPH3 SHTN1 SF1	5.44e-07	65	93	6	int:BCHE
Interaction	ARHGAP12 interactions	PRR12 WASL RAPH1 FNBP4 WASF1 SF1	7.13e-07	68	93	6	int:ARHGAP12
Interaction	DAAM2 interactions	FMNL3 FHDC1 DIAPH3 FMNL2 FMNL1	8.35e-07	38	93	5	int:DAAM2
Interaction	DAAM1 interactions	FMNL3 FMN1 FHDC1 DIAPH3 FMNL2 FMNL1	1.00e-06	72	93	6	int:DAAM1
Interaction	KDM1A interactions	TRERF1 PRR12 IRS4 SALL2 KMT2B ZFHX4 PELP1 RAPH1 RANBP9 ZFHX3 ZNF318 DIAPH3 SHTN1 TRRAP SF3B2 HTT VCPIP1	1.25e-06	941	93	17	int:KDM1A
Interaction	RCOR1 interactions	TRIM66 IRS4 SALL2 KMT2B ZFHX4 RAPH1 ZNF827 RANBP9 ZFHX3 ZNF318 SHTN1 VCPIP1	2.84e-06	494	93	12	int:RCOR1
Interaction	WAS interactions	EVL WIPF1 ENAH KDM6B WIPF2 VASP	3.50e-06	89	93	6	int:WAS
Interaction	OSTF1 interactions	WASL WASHC1 FASLG WASF1 SF1 HTT	3.74e-06	90	93	6	int:OSTF1
Interaction	WWTR1 interactions	PRRG2 BPTF IRS4 RAPH1 ENAH ZNF318 DIAPH3 SHTN1 TRRAP HTT VCPIP1	3.89e-06	422	93	11	int:WWTR1
Interaction	ABI1 interactions	NHSL1 EVL WASL RAPH1 ENAH WASF1 WIPF2 VASP	9.00e-06	223	93	8	int:ABI1
Interaction	FMNL1 interactions	FMNL3 GRID2IP FMN1 DIAPH3 FMNL2 FMNL1	1.13e-05	109	93	6	int:FMNL1
Interaction	WBP4 interactions	SETD1B WIPF1 FMN1 DMRTB1 SF1 SF3B2	1.13e-05	109	93	6	int:WBP4
Interaction	FYB1 interactions	EVL ENAH FASLG VASP	1.22e-05	31	93	4	int:FYB1
Interaction	DIAPH2 interactions	FMNL3 FHDC1 DIAPH3 FMNL2 FMNL1	1.56e-05	68	93	5	int:DIAPH2
Interaction	NCK1 interactions	NHSL1 WASL WIPF1 WIPF3 FASLG TRRAP WASF1 WIPF2	1.73e-05	244	93	8	int:NCK1
Interaction	DIAPH1 interactions	FMNL3 WASL FHDC1 DIAPH3 FMNL2 FMNL1 VASP	1.73e-05	176	93	7	int:DIAPH1
Interaction	PRPF18 interactions	FMNL3 ZNF526 FHDC1 DIAPH3 FMNL2 FMNL1	1.96e-05	120	93	6	int:PRPF18
Interaction	ALG13 interactions	PRR12 TRIM66 DMRTB1 R3HDM1 VASP SF1 ALG13	2.23e-05	183	93	7	int:ALG13
Interaction	DIAPH3 interactions	FMNL3 FMN1 FHDC1 DIAPH3 FMNL2 FMNL1	2.48e-05	125	93	6	int:DIAPH3
Interaction	GRID2IP interactions	GRID2IP FHDC1 FMNL1	2.63e-05	13	93	3	int:GRID2IP
Interaction	BAG2 interactions	ESRP2 TRIM66 BPTF SALL2 ENAH FNBP4 ZNF318 R3HDM1 VASP SF1 FOXK1 HTT	2.86e-05	622	93	12	int:BAG2
Interaction	ABI3 interactions	EVL WASHC1 ENAH WASF1 VASP	3.65e-05	81	93	5	int:ABI3
Interaction	EVL interactions	EVL ENAH WIPF2 VASP HTT	4.10e-05	83	93	5	int:EVL
Interaction	HDAC1 interactions	TRERF1 BPTF IRS4 KMT2B ZFHX4 RAPH1 ZNF827 RANBP9 SKOR1 ZFHX3 ZNF318 DIAPH3 SHTN1 SF3B2 FOXK1 VCPIP1	4.35e-05	1108	93	16	int:HDAC1
Interaction	WIPF2 interactions	EVL WASL WIPF3 WIPF2	4.57e-05	43	93	4	int:WIPF2
Interaction	TCERG1 interactions	EVL FMN1 WIPF2 FMNL1 SF1 SF3B2 HTT	4.89e-05	207	93	7	int:TCERG1
Interaction	WIPF3 interactions	WASL WIPF3 WIPF2	5.10e-05	16	93	3	int:WIPF3
Interaction	ABI2 interactions	NHSL1 WASL WIPF1 RAPH1 WASHC1 ENAH WASF1 VASP	5.35e-05	286	93	8	int:ABI2
Interaction	ITSN2 interactions	WASL WIPF1 WIPF3 FNBP4 FASLG WIPF2	6.15e-05	147	93	6	int:ITSN2
Interaction	DYRK1B interactions	ENAH RANBP9 SKOR1 TRRAP FOXK1	6.38e-05	91	93	5	int:DYRK1B
Interaction	NCKAP1 interactions	NHSL1 ENAH WASF1 WIPF2 MYO16 CAP2 HTT	6.78e-05	218	93	7	int:NCKAP1
Interaction	ACTBL2 interactions	FMNL3 WASH3P WASL WASHC1 PXK CAP2 MAP3K4 HTT	6.81e-05	296	93	8	int:ACTBL2
Interaction	XIRP1 interactions	EVL ENAH VASP	7.38e-05	18	93	3	int:XIRP1
Interaction	SPTA1 interactions	EVL ENAH FASLG VASP HTT	7.45e-05	94	93	5	int:SPTA1
Interaction	GRB2 interactions	WASL IRS4 PDE4D WIPF1 ZNF341 WIPF3 ZBTB12 FASLG WASF1 WIPF2 VASP SF3B2 HTT	8.21e-05	806	93	13	int:GRB2
Interaction	PHF20 interactions	SETD1B KMT2B KDM6B HTT	1.05e-04	53	93	4	int:PHF20
Interaction	WASH4P interactions	WASH3P WASH4P	1.26e-04	4	93	2	int:WASH4P
Interaction	YAP1 interactions	TRERF1 PRRG2 BPTF WASL IRS4 KMT2B ENAH FNBP4 GLIS3 ZNF318 SHTN1 TRRAP VASP SF3B2 VCPIP1	1.40e-04	1095	93	15	int:YAP1
Interaction	SH3RF1 interactions	EVL WASL WIPF1 NAF1 DMRTB1	1.44e-04	108	93	5	int:SH3RF1
Interaction	PHLPP1 interactions	IRS4 RAPH1 ZNF318 DIAPH3 SHTN1 SF1 SF3B2 VCPIP1	1.54e-04	333	93	8	int:PHLPP1
Interaction	SRGAP3 interactions	RAPH1 FASLG WASF1 HTT	1.59e-04	59	93	4	int:SRGAP3
Interaction	FYN interactions	EVL WASL PDE4D FMN1 ENAH FNBP4 FASLG WASF1 HTT	1.69e-04	431	93	9	int:FYN
Interaction	NHSL3 interactions	NHSL1 EVL ENAH WASF1 VASP	1.78e-04	113	93	5	int:NHSL3
Interaction	PHF21A interactions	IRS4 SALL2 KMT2B ZFHX4 NAF1 ZFHX3 ZNF318 DIAPH3	1.88e-04	343	93	8	int:PHF21A
Interaction	WASL interactions	WASL WIPF1 WIPF3 WASF1 WIPF2	2.09e-04	117	93	5	int:WASL
Interaction	PACSIN2 interactions	WASL WIPF1 FASLG WIPF2 PXK HTT	2.17e-04	185	93	6	int:PACSIN2
Interaction	ASH2L interactions	SETD1B KMT2B PELP1 KDM6B FMNL1 FOXK1 HTT	2.27e-04	265	93	7	int:ASH2L
Interaction	ITCH interactions	TRERF1 TRIM66 WASL GLIS3 KDM6B SHTN1 SF1 HTT	2.42e-04	356	93	8	int:ITCH
Interaction	EIF2AK1 interactions	NAF1 FASLG TRRAP	2.87e-04	28	93	3	int:EIF2AK1
Interaction	ENAH interactions	EVL RAPH1 ENAH FMNL2 VASP	2.95e-04	126	93	5	int:ENAH
Interaction	PDE6B interactions	DIAPH3 FMNL2 FMNL1	3.19e-04	29	93	3	int:PDE6B
Interaction	YWHAZ interactions	NHSL1 EVL IRS4 PDE4D PPP3CB RAPH1 ASXL3 ENAH R3HDM1 SHTN1 WASF1 SF3B2 FOXK1 MAP3K4 HTT C6orf132	3.28e-04	1319	93	16	int:YWHAZ
Interaction	BAIAP2L1 interactions	ESPN GRID2IP FASLG FMNL2 VASP	3.29e-04	129	93	5	int:BAIAP2L1
Interaction	TOP3B interactions	ESRP2 PRR12 NHSL1 SCAF1 HOXB4 SETD1B KMT2B ZNF628 PELP1 ZNF827 ZNF341 ZBTB4 KDM6B TRRAP FOXK1 HTT C6orf132	3.64e-04	1470	93	17	int:TOP3B
Interaction	NCKIPSD interactions	WASL DMRTB1 DIAPH3 FASLG HTT	4.34e-04	137	93	5	int:NCKIPSD
Interaction	CACNA1G interactions	RANBP9 TRRAP	4.36e-04	7	93	2	int:CACNA1G
Interaction	NCOA6 interactions	SETD1B KMT2B RANBP9 SF1 HTT	5.63e-04	145	93	5	int:NCOA6
Interaction	RFXANK interactions	ESRP2 BPTF FOXK1 HTT VCPIP1	5.80e-04	146	93	5	int:RFXANK
Interaction	WASF2 interactions	NHSL1 EVL WASL WASF1 VASP	5.80e-04	146	93	5	int:WASF2
Interaction	PIK3R1 interactions	TRIM66 IRS4 PDE4D FASLG WASF1 MYO16 PXK HTT	6.38e-04	412	93	8	int:PIK3R1
Interaction	SH3KBP1 interactions	WASL PPP3CB WIPF1 USP51 RAPH1 WIPF2 MAP3K4	6.41e-04	315	93	7	int:SH3KBP1
Interaction	NFIX interactions	PRR12 BPTF KMT2B ZFHX4 ZFHX3 TRRAP	6.45e-04	227	93	6	int:NFIX
Interaction	NUP62CL interactions	BPTF WASH3P WASHC1	6.60e-04	37	93	3	int:NUP62CL
Interaction	SMG7 interactions	PRR12 TRIM66 SALL2 ZNF318 R3HDM1 VASP ALG13	6.90e-04	319	93	7	int:SMG7
Interaction	GSC interactions	PRR12 ZFHX4 ASXL3 ZFHX3	7.06e-04	87	93	4	int:GSC
Interaction	TRIM9 interactions	EVL ENAH VASP MYO16	8.02e-04	90	93	4	int:TRIM9
GeneFamily	Wiskott-Aldrich Syndrome protein family	WASH3P WASL WASH4P WASHC1 WHAMM WASH2P WASF1 JMY	1.73e-16	16	63	8	14
GeneFamily	ENAH/VASPs	EVL ENAH VASP	4.03e-08	3	63	3	946
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF526 SALL2 ZNF628 ZNF827 ZNF341 ZIC5 ZBTB4 GLIS3 ZFHX3 ZBTB12 ZNF318	3.35e-05	718	63	11	28
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZFHX4 ZFHX3	1.22e-03	15	63	2	529
GeneFamily	OTU domain containing	VCPIP1 ALG13	1.57e-03	17	63	2	669
GeneFamily	PHD finger proteins	TRIM66 BPTF KMT2B	3.82e-03	90	63	3	88
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETD1B KMT2B	6.24e-03	34	63	2	487
GeneFamily	Actins\|Deafness associated genes	ESPN TPRN PCDH15	7.19e-03	113	63	3	1152
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	PDE4D PPP3CB ZFHX4 RAPH1 NRXN2 ASXL3 PCLO ADGRB1 ZFHX3 ZNF318 R3HDM1 SHTN1 FMNL2 WASF1 PXK	1.02e-05	1106	95	15	M39071
CoexpressionAtlas	FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_500	IRS4 SALL2 USP51 NRXN2 ZIC5 RNF44 DGKK NAF1 ZBTB4 PCDH15 GLIS3 FHDC1 SHTN1	1.86e-07	489	92	13	Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000	ESRP2 IRS4 SALL2 ZFHX4 USP51 NRXN2 ZIC5 RNF44 DGKK NAF1 ZBTB4 PCDH15 GLIS3 FHDC1 SHTN1 FMNL1	4.14e-06	976	92	16	Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500	IRS4 SALL2 USP51 NRXN2 FMN1 TPRN PCLO RNF44 DGKK GLIS3 SHTN1	9.70e-06	495	92	11	Facebase_RNAseq_e8.5_Floor Plate_500
CoexpressionAtlas	facebase_RNAseq_e9.5_OlfPlac_2500_K3	ESPN PRR12 PRRG2 SCAF1 SALL2 SETD1B ZNF628 RNF44 DGKK NAF1 WIPF3 GLIS3 ZFHX3 ZBTB12 WASF1 ALG13	4.65e-05	1187	92	16	facebase_RNAseq_e9.5_OlfPlac_2500_K3
CoexpressionAtlas	gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K0	PRR12 PRRG2 EVL SCAF1 ATF5 ZNF628 ZNF827 DGKK WIPF3 GLIS3 ZFHX3 ZBTB12 KDM6B MARCHF11 WASF1 WIPF2	1.08e-04	1275	92	16	gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K0
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	EVL PDE4D WIPF1 RAPH1 FMN1 ENAH HS3ST4	1.55e-07	187	95	7	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	Thalamus\|World / BrainAtlas - Mouse McCarroll V32	GRID2IP ZFHX4 ZIC5 ZFHX3 FHDC1 LMOD2	1.86e-07	116	95	6	5ddfb2dd5459ff6d7ae38163a38eae64fda283b7
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KMT2B NAF1 LIX1L FHDC1 FMNL1 SEMA4G	1.37e-06	163	95	6	953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tfh\|GI_large-bowel / Manually curated celltypes from each tissue	TRIM66 SALL2 SETD1B GLIS3 SHTN1 TRRAP	1.37e-06	163	95	6	4104d3b9748b39cb0744c9be76db21bdda566a0d
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HOXB4 KMT2B USP51 LIX1L ZFTA MEX3C	2.29e-06	178	95	6	c87945146b2734141f07b39d268e0d8086ee0364
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 ASXL3 PCLO DGKK PCDH15 MYO16	2.77e-06	184	95	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 ASXL3 PCLO DGKK PCDH15 MYO16	2.77e-06	184	95	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 ASXL3 PCLO DGKK PCDH15 MYO16	2.77e-06	184	95	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Hippocampus-Neuronal-Excitatory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	WASL MICAL2 WIPF3 HS3ST4 WASF1 FMNL1	3.23e-06	189	95	6	4b90d181eb0a42814eeb23bc82e52fd3a12392a7
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EVL ASXL3 ENAH PCDH15 GLIS3 MYO16	3.76e-06	194	95	6	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR-_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVL PDE4D WIPF1 FASLG JMY FMNL1	4.11e-06	197	95	6	aa160ebf2f1913b83e0b1ae1de1d9e2089342948
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Cortical_neuron\|10w / Sample Type, Dataset, Time_group, and Cell type.	EVL ZFHX4 NRXN2 ASXL3 PCLO ZFHX3	4.48e-06	200	95	6	68c90376e2779434e4ad8dc6dd3b44baa700e2f4
ToppCell	(53)_Lymphoid_DC\|World / shred on Cell_type and subtype	RAPH1 NRXN2 ASXL3 FHDC1 SHTN1 FMNL2	5.61e-06	208	95	6	30212cfacad94a7cc562a69efa73a31259851515
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SKOR1 MARCHF11 FMNL1 MYO16 SEMA4G	2.94e-05	167	95	5	9efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCell	Cerebellum-Neuronal-Inhibitory\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SKOR1 MARCHF11 FMNL1 MYO16 SEMA4G	2.94e-05	167	95	5	904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell	NS-critical-LOC-Lymphoid-NK\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EVL PDE4D WIPF3 FASLG MEX3C	3.29e-05	171	95	5	adda76991d9b150bb8ccf3989b7cbbf41843cf0b
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NHSL1 USP51 ACR ENAH ALG13	3.77e-05	176	95	5	3766e0533b103ec92ac75eba3df02e287efc53fa
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NHSL1 USP51 ACR ENAH ALG13	3.77e-05	176	95	5	aa1bada2175d8370fc71939a607407155259d195
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 EVL PDE4D FMNL1 VASP	4.78e-05	185	95	5	a2cae8c657e4f4d121476798e424876f7e247973
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 EVL PDE4D FMNL1 VASP	4.78e-05	185	95	5	d50406a9a5b8d75110ba5985741aa2293950c543
ToppCell	10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-ILC_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	EVL PDE4D PEG10 JMY CAP2	5.03e-05	187	95	5	f31d865ce2a21bdf64dbe29ee3e4505ab482604a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NAF1 KDM6B JMY SF1 ALG13	5.16e-05	188	95	5	939790f133eac9c12d08db6ddb5f08f5107844e3
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-Activated_T\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVL PDE4D WIPF1 FASLG FMNL1	5.29e-05	189	95	5	c38157c8cf5c0c1f560011ef5cc5892a049ee2b7
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PDE4D MICAL2 R3HDM1 HS3ST4 WASF1	5.29e-05	189	95	5	a75226616340045b581d08429d2e123e041dee55
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EVL PDE4D PCDH15 GLIS3 MYO16	5.29e-05	189	95	5	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 NRXN2 PEG10 PCDH15 MARCHF11	5.43e-05	190	95	5	e792e42fc49472eaf974eb0905819eb51a1da8e5
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVL PDE4D RAPH1 KDM6B CAP2	5.43e-05	190	95	5	d85b34d19af43d83ebe728f3c7bbefd3792df4a6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PDE4D MICAL2 R3HDM1 HS3ST4 WASF1	5.43e-05	190	95	5	49e09cdb843b3d889a06a811aa5affae68b25a75
ToppCell	COVID-19-lung-CD8+_T_cells\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRERF1 EVL WIPF1 FASLG FMNL1	5.56e-05	191	95	5	543f8ae07cc2e6950c888115a5ca9445e3c0f618
ToppCell	ILEUM-inflamed-(1)_T_cell-(1)_Th17_Trm\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	EVL PDE4D WIPF1 JMY MAP3K4	5.70e-05	192	95	5	12f7ea575da5d650c740e6060f5dab0478e563dd
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 NRXN2 PEG10 PCDH15 MARCHF11	5.70e-05	192	95	5	550a6574a93acadb43c449094565c73ca51a0c5c
ToppCell	ILEUM-non-inflamed-(1)_Th17_Trm\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	EVL PDE4D WIPF1 JMY MAP3K4	5.70e-05	192	95	5	7347ff4dedd1aaa489c4f15e5ae647a4ce39ac72
ToppCell	NS-control-d_0-4-Lymphoid-Treg\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FMNL3 EVL HOXB4 WIPF1 FMNL1	5.70e-05	192	95	5	ef252dd9df161f665f53c047c0514381f80d6683
ToppCell	control-Lymphoid-Treg\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FMNL3 EVL HOXB4 WIPF1 FMNL1	5.70e-05	192	95	5	9067e90b7c2d734100d6e5026d753113bf9428a3
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EVL ASXL3 PCDH15 GLIS3 MYO16	5.84e-05	193	95	5	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	T_cells-CD56_bright_CD16-_NK_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	ESPN WIPF3 ZFHX3 WASF1 CAP2	5.84e-05	193	95	5	826457e2aafdb61ead8a0a44d8cf9088d310684b
ToppCell	367C-Myeloid-Dendritic-cDC1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	TRERF1 EVL SHTN1 FMNL2 VCPIP1	6.14e-05	195	95	5	fca958f73de450ef813444d3dc590353f1c55326
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MICAL2 R3HDM1 HS3ST4 WASF1 CAP2	6.14e-05	195	95	5	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-TRDV2/TRGV9_gdT\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVL PDE4D WIPF1 FASLG FMNL1	6.29e-05	196	95	5	8e20ffe39157619b1d02b48d2cf9d62f26bdb3e8
ToppCell	PSB-critical-LOC-Lymphoid\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EVL WIPF1 DIAPH3 FASLG FMNL1	6.29e-05	196	95	5	7b5c2a4cdea9a944f83bfc2c493d3076c3daaeaa
ToppCell	control-Lymphoid\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FMNL3 EVL WIPF1 FASLG FMNL1	6.29e-05	196	95	5	8ed172bb3a95f09722476f0880ae246561777d98
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVL PDE4D WIPF1 FASLG FMNL1	6.44e-05	197	95	5	07475c0785534ba845acec0e33310d57ad7352e6
ToppCell	NS-control-d_0-4-Lymphoid\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FMNL3 EVL WIPF1 FASLG FMNL1	6.44e-05	197	95	5	bd3f2d68eb108fe31e217c9124183920e7c82582
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-Activated_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVL PDE4D WIPF1 FASLG FMNL1	6.44e-05	197	95	5	dfec2afd1cbe218c9234ce7d4b5a5839b268398d
ToppCell	mLN-(5)_Dendritic_cell-(53)_Lymphoid_DC\|mLN / shred on region, Cell_type, and subtype	RAPH1 NRXN2 ASXL3 SHTN1 FMNL2	6.60e-05	198	95	5	da84c76afe835aeee39da04b63c03549218b5d91
ToppCell	mLN-Dendritic_cell-Lymphoid_DC\|mLN / Region, Cell class and subclass	RAPH1 NRXN2 ASXL3 SHTN1 FMNL2	6.60e-05	198	95	5	3965a9f1e8a51a196e5349aaca5fa5ed1cd8ee92
ToppCell	Neuron\|World / Primary Cells by Cluster	ASXL3 PCLO R3HDM1 SHTN1 WASF1	6.75e-05	199	95	5	1f8104fd92f04690b41d9d07ac08dc59d76bb97d
ToppCell	Neuron-Postmitotic\|World / Primary Cells by Cluster	ASXL3 PCLO R3HDM1 SHTN1 WASF1	6.75e-05	199	95	5	1973527f8a7d4c6490d75c0d0ea153688166a08b
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	NRXN2 ASXL3 PCLO R3HDM1 SHTN1	6.92e-05	200	95	5	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	EVL ZFHX4 NRXN2 ZFHX3 KDM6B	6.92e-05	200	95	5	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	Neuronal-Excitatory\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PDE4D MICAL2 R3HDM1 HS3ST4 WASF1	6.92e-05	200	95	5	4409065bc7aa995354c71e0f9d6f3726cf393d6b
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Poorly_Differentiated_Synovial_Sarcoma\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	ESPN ZIC5 HS3ST4 LMOD2	1.04e-04	114	95	4	674d34a35f403ba938a2a109a68bf34bdc3657c9
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Poorly_Differentiated_Synovial_Sarcoma-3\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	ESPN ZIC5 HS3ST4 LMOD2	1.04e-04	114	95	4	cbed6161fc307056ef1ac08b0f62c8c544866884
ToppCell	Control-Epithelial_alveolar-AT_2-AT1-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IRS4 USP51 WIPF3 SHTN1	1.15e-04	117	95	4	c6fc72608d56a389bcd87b5dc98a11e39b79bcb2
ToppCell	356C-Epithelial_cells-Epithelial-H_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MYPOP ZNF318 MEX3C MAP3K4	1.19e-04	118	95	4	08bdf7bc3c9dcbc0f690658fe14e6cc4b9581698
ToppCell	356C-Epithelial_cells-Epithelial-H_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MYPOP ZNF318 MEX3C MAP3K4	1.19e-04	118	95	4	3b077ad5c68c01b3fcc93f203cb130bb90705af9
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_A-3\|TCGA-Thymus / Sample_Type by Project: Shred V9	GRID2IP INHBB ACR PCDH15	1.63e-04	128	95	4	f6b2be273e8b9002849fd892071a04f9fb76dc66
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ZFHX4 INHBB WIPF3 WASF1	1.73e-04	130	95	4	c70fb77324916d220d842a575558a8245c276599
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ZFHX4 INHBB WIPF3 WASF1	2.56e-04	144	95	4	e2a2f260f5ebaaef46248d199c407a15ce9d024a
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	INHBB MICAL2 ZFTA FHDC1	2.91e-04	149	95	4	4034805c4eefb8bfb3a357273ccbdb77283ea4a5
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Crh_(MGE-derived_cortical_interneurons--Martinotti_cells)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	IRS4 DGKK SKOR1	3.00e-04	61	95	3	351078cb41e285af7e117820ee607d4c24332a9d
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Crh_(MGE-derived_cortical_interneurons--Martinotti_cells)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	IRS4 DGKK SKOR1	3.00e-04	61	95	3	aae9ba2240812258d1c9e0e443d4f817b4796131
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_E\|390C / Donor, Lineage, Cell class and subclass (all cells)	ESPN TRIM66 KDM6B FOXK1	3.38e-04	155	95	4	98d8432739965dd1ab77c899cb6321f7f05eaa46
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Pld5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ESPN ZFHX4 R3HDM1 FMNL1	3.72e-04	159	95	4	a082e770fa757c4a1d3ed13d53f83297e36faf05
ToppCell	Basal_cells-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	INHBB ASXL3 WIPF3 HS3ST4	3.81e-04	160	95	4	b223cc47e68a29df4758c5ccf8f6dbffe2a6fa1d
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZFHX4 NRXN2 ZIC5 WIPF3	3.90e-04	161	95	4	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZFHX4 NRXN2 ZIC5 WIPF3	3.90e-04	161	95	4	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZFHX4 NRXN2 ZIC5 WIPF3	3.90e-04	161	95	4	cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D GLIS3 MARCHF11 MYO16	4.00e-04	162	95	4	285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZFHX4 NRXN2 ZIC5 WIPF3	4.00e-04	162	95	4	96c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMN1 LIX1L FHDC1 SEMA4G	4.09e-04	163	95	4	132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM66 MYPOP ATF5 SHTN1	4.19e-04	164	95	4	b895674ed2df87db8fbfb30b7e31620945588491
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-Th1\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVL ZNF526 PDE4D ZBTB4	4.48e-04	167	95	4	9c55ec8f70b86d4d3d5c2a6ecd9bff2dafe68c11
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDE4D WHAMM JMY MAP3K4	4.48e-04	167	95	4	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	3'_v3-Lung-Lymphocytic_Invariant-Inducer-like-ILC3\|Lung / Manually curated celltypes from each tissue	ESPN INHBB PCLO JMY	4.48e-04	167	95	4	0614d077b47a87f726068615548d0b0a216627be
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ESPN TRIM66 KDM6B FMNL2	4.48e-04	167	95	4	6c2dade24a88af04b2c90a7e4f8dd7ccea9e94d1
ToppCell	Control-NK\|Control / Disease group and Cell class	NHSL1 SALL2 ZFHX3 DIAPH3	4.58e-04	168	95	4	683d389c8a1e791bfc773e63148115a21a6566db
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ESPN TRIM66 KDM6B FMNL2	4.58e-04	168	95	4	d8f485f8459532a2cb0bef899e6569142cf75685
ToppCell	facs-GAT-Fat-18m-Myeloid-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDM6B SHTN1 FMNL1 VASP	4.69e-04	169	95	4	7a7416fcbffcf57d19b477d9da091e04e3499524
ToppCell	facs-GAT-Fat-18m-Myeloid\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDM6B SHTN1 FMNL1 VASP	4.69e-04	169	95	4	0e1a99cd77edcf32bcb513abd247b2b27409ac63
ToppCell	facs-GAT-Fat-18m-Myeloid-myeloid_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDM6B SHTN1 FMNL1 VASP	4.69e-04	169	95	4	9bbad31ef03078f5aa456f2e1b17b49c91545ff0
ToppCell	droplet-Liver-Npc\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVL WIPF1 FMNL1 VASP	4.79e-04	170	95	4	09c836840216905d545a25a4fc1bbd0699576c77
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ZIC5 INHBB PCLO DGKK	4.79e-04	170	95	4	98d13dbd76a826e47d55553f9d11f71c043b573e
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-club_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ESRP2 PCDH15 FHDC1 C6orf132	4.79e-04	170	95	4	6de3778e8257c3330db0780c59238ca501fe5059
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-club_cell-club_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ESRP2 PCDH15 FHDC1 C6orf132	4.79e-04	170	95	4	60887da674ef1a735bad618235608312d8de63d3
ToppCell	droplet-Liver-Npc-18m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVL WIPF1 FMNL1 VASP	4.90e-04	171	95	4	e9c42ce444d42cbb4f97e81393756531bfe61637
ToppCell	droplet-Liver-nan-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMN1 ZBTB4 ENAH FMNL2	5.01e-04	172	95	4	1f335ccb92b22d0412954e8fc3af212f96410b67
ToppCell	droplet-Liver-nan-3m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMN1 ZBTB4 ENAH FMNL2	5.01e-04	172	95	4	bb96c896d125e10b71e94e2bdad243899045af5c
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KMT2B ZNF827 FMNL2 ALG13	5.12e-04	173	95	4	0a0cd40bb5f61431fe34758626c8a63ec610a8a5
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRIM66 FASLG LMOD2 FMNL2	5.23e-04	174	95	4	d77fa525d5c87c190b4a10787b270eabd16c610f
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRIM66 RAPH1 ZBTB12 C6orf132	5.46e-04	176	95	4	87de432c680b80555342afac864599bbc002c040
ToppCell	facs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 ENO4 SALL2 DIAPH3	5.58e-04	177	95	4	8a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCell	facs-Lung-nan-3m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESRP2 PCLO FHDC1 C6orf132	5.58e-04	177	95	4	e5070934c674a46e070b0d52b9a374516bf6aea1
ToppCell	droplet-Lung-LUNG-30m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF526 ZFHX4 FHDC1 C6orf132	5.58e-04	177	95	4	7ac99ff16df94b4e08d361e3d98a7b3af8d6ee3b
ToppCell	facs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 ENO4 SALL2 DIAPH3	5.58e-04	177	95	4	e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCell	facs-Lung-nan-3m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESRP2 PCLO FHDC1 C6orf132	5.58e-04	177	95	4	b37d821f4f3204daf7c568ac17a0af0ba97273d6
ToppCell	droplet-Lung-LUNG-30m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF526 ZFHX4 FHDC1 C6orf132	5.58e-04	177	95	4	092a345cb802f183322aa5542341ba2d96d4f06a
ToppCell	21-Trachea-Immune-Hematopoietic,_Natural_Killer_Cell\|Trachea / Age, Tissue, Lineage and Cell class	EVL WIPF1 FASLG FMNL1	5.70e-04	178	95	4	d2e1f6b7933b7da2682393e5ff5e03cdd8f64761
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-Th17\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVL PDE4D WIPF1 FASLG	5.82e-04	179	95	4	61472d75f4a3c4374eeb55ef79982ae4054dadaa
ToppCell	10x5'v1-week_12-13-Lymphocytic_NK-T_NK-ILC_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PEG10 FASLG JMY CAP2	5.82e-04	179	95	4	bc95c3e7edc5fc6fc913b09f087d221df64c6f48
Drug	AC1LD8HW	FMNL3 FMN1 FNBP4 DIAPH3 FMNL2 FMNL1 VASP	2.57e-08	75	94	7	CID000644061
Drug	F-dd	FMNL3 FMN1 FNBP4 FHDC1 DIAPH3 FMNL2 FMNL1	4.42e-08	81	94	7	CID006102682
Drug	etheno-NAD	WASL WIPF1 RAPH1 ENAH WASF1 WIPF2 VASP	2.50e-07	104	94	7	CID005288160
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA	BPTF ATF5 SETD1B INHBB FNBP4 ZFHX3 MEX3C	8.20e-06	175	94	7	1058_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	BPTF ATF5 INHBB RNF44 ZFHX3 CAP2 MEX3C	9.16e-06	178	94	7	1112_DN
Drug	methenamine silver	FMNL3 FMN1 FNBP4 DIAPH3 FMNL2 FMNL1 VASP	2.01e-05	201	94	7	CID000004101
Disease	tauopathy (implicated_via_orthology)	EVL ENAH VASP	3.35e-06	10	91	3	DOID:680 (implicated_via_orthology)
Disease	Intellectual Disability	PRR12 BPTF ZNF526 NRXN2 KDM6B TRRAP WASF1 HTT ALG13	1.01e-05	447	91	9	C3714756
Disease	testosterone measurement	MYPOP ZFHX4 ZIC5 TPRN DGKK ZBTB4 FNBP4 GLIS3 ZFHX3 ZNF318 HS3ST4 KDM6B MYO16 CAP2	3.50e-05	1275	91	14	EFO_0004908
Disease	vital capacity	TRIM66 ZNF628 ZNF341 PCLO ZBTB4 GLIS3 ZFHX3 DIAPH3 SHTN1 JMY SF3B2 MYO16 FOXK1	1.06e-04	1236	91	13	EFO_0004312
Disease	free androgen index	MYPOP ZFHX4 ZIC5 FNBP4 GLIS3 ZNF318 CAP2	1.61e-04	374	91	7	EFO_0007005
Disease	neurotic disorder	PDE4D ASXL3 PCLO GLIS3	2.75e-04	101	91	4	EFO_0004257
Disease	thyrotoxic periodic paralysis	ZFHX3 FHDC1	5.08e-04	11	91	2	MONDO_0019201
Disease	disease recurrence, colon carcinoma	TPRN FOXK1 MAP3K4	5.31e-04	51	91	3	EFO_0004952, EFO_1001950
Disease	Nonsyndromic Hearing Loss and Deafness, Autosomal Recessive	ESPN TPRN PCDH15	5.31e-04	51	91	3	cv:CN043650
Disease	corpus callosum posterior volume measurement	ENO4 ZBTB4 SHTN1	5.62e-04	52	91	3	EFO_0010298
Disease	myeloid white cell count	SETD1B MICAL2 ENAH WIPF3 GLIS3 ZFHX3 FASLG FMNL2 WIPF2 HTT	6.26e-04	937	91	10	EFO_0007988
Disease	HOMA-B	PCDH15 GLIS3 DIAPH3	6.63e-04	55	91	3	EFO_0004469
Disease	sphingomyelin 14:0 measurement	PDE4D ZFHX3	1.24e-03	17	91	2	EFO_0010390
Disease	dyslexia	SCAF1 PDE4D HS3ST4 HTT	1.61e-03	162	91	4	EFO_0005424
Disease	Nonsyndromic genetic hearing loss	ESPN TPRN PCDH15	1.70e-03	76	91	3	cv:C5680182
Disease	Deaf Mutism	ESPN PCDH15	1.72e-03	20	91	2	C4082305
Disease	Deafness, Acquired	ESPN PCDH15	1.72e-03	20	91	2	C0751068
Disease	Hearing Loss, Extreme	ESPN PCDH15	1.72e-03	20	91	2	C0086395
Disease	Complete Hearing Loss	ESPN PCDH15	1.72e-03	20	91	2	C0581883
Disease	Prelingual Deafness	ESPN PCDH15	1.72e-03	20	91	2	C0011052
Disease	Bilateral Deafness	ESPN PCDH15	1.72e-03	20	91	2	C3665473
Disease	neuroticism measurement, cognitive function measurement	SCAF1 ASXL3 PCLO ENAH GLIS3 ZFHX3 SHTN1	1.86e-03	566	91	7	EFO_0007660, EFO_0008354
Disease	Nonsyndromic Deafness	ESPN TPRN PCDH15	2.03e-03	81	91	3	C3711374
Disease	cortical thickness	ENO4 NHSL1 KMT2B GLIS3 ZNF318 DIAPH3 SHTN1 FMNL2 MYO16 PXK	2.27e-03	1113	91	10	EFO_0004840
Disease	Ovarian Serous Adenocarcinoma	TRRAP MAP3K4	2.28e-03	23	91	2	C1335177
Disease	Deafness	ESPN PCDH15	2.69e-03	25	91	2	C0011053
Disease	sleep duration, low density lipoprotein cholesterol measurement	ZNF827 R3HDM1 HTT	2.83e-03	91	91	3	EFO_0004611, EFO_0005271
Disease	response to angiotensin-converting enzyme inhibitor, response to angiotensin receptor blocker, angioedema	PDE4D DIAPH3	2.91e-03	26	91	2	EFO_0005325, EFO_0005532, EFO_0010735

Protein segments in the cluster

Peptide	Gene	Start	Entry
ASLPPPPPPPPPPPP	ALG13	916	Q9NP73
EKPPSPPPPPPPPPP	ANTXRL	396	A6NF34
PPPPPPLPPPPPAPV	ANTXRL	406	A6NF34
APPAQPPPPPPPPPP	ADGRB1	1406	O14514
PPPPPPPQQPLPPPP	ADGRB1	1416	O14514
PPPSPPPPPPPPASP	ACR	346	P10323
PPPPPPPASPLPPPP	ACR	351	P10323
PPASPLPPPPPPPPP	ACR	356	P10323
GVPPPPPPPPPPPLP	DIAPH3	586	Q9NSV4
PAPPAPPAPPPSPPP	BPTF	2801	Q12830
HPPPPPPPPPPPPLA	ASXL3	2016	Q9C0F0
PPPPPPPPLALPPPP	ASXL3	2021	Q9C0F0
PPPLALPPPPPPPPP	ASXL3	2026	Q9C0F0
LPPPPPPPPPLPPPL	ASXL3	2031	Q9C0F0
PLPPPSPPPLPPPPL	ATF5	121	Q9Y2D1
PPPPPPPPPPLPPGQ	R3HDM1	596	Q15032
PPPPPPPATAAPPPP	RANBP9	71	Q96S59
PPATAAPPPPPPPPP	RANBP9	76	Q96S59
APPPPPPPPPPPASA	RANBP9	81	Q96S59
PTPPPPPPIPAPLPP	RAPH1	761	Q70E73
PPSPVPAPPPPPPPT	RAPH1	931	Q70E73
PPPPPPPPPLPNSPA	FMN1	921	Q68DA7
PPPPPLPGEPPIPPP	FHDC1	61	Q9C0D6
PPPPPPPAPPPAPPL	DGKK	31	Q5KSL6
PPPPPPPPPPLPVAK	JMY	816	Q8N9B5
STPPPPPPPPGPPPA	MYO16	1571	Q9Y6X6
TPPPTPAAPPPPPPP	INHBB	31	P09529
PPPPPSFPPPPPPPG	ESPN	431	B1AK53
PPPPPPPPPPLPEAA	ESPN	596	B1AK53
PPGLPLPPPPLPPPP	KDM6B	241	O15054
SPVATPPPPPPPPPP	LMOD2	416	Q6P5Q4
LPPPPPPLPPPGPPP	CAP2	231	P40123
PPAPPPPPVPSPPFP	NHSL1	931	Q5SYE7
PPPPPPLPPPTSPKP	PCLO	2421	Q9Y6V0
CPLQPPPPPPLPPPP	PDE4D	71	Q08499
PPPPPLPPPPPPPGA	PDE4D	76	Q08499
GPPPPPPPPVPPPPT	EVL	181	Q9UI08
QPPPPPPPPPPPPSY	PEG10	691	Q86TG7
GPPPAPPPPAPPPPP	LIX1L	41	Q8IVB5
PPLCPPPPPPVSPPP	KMT2B	426	Q9UMN6
PPPPPVSPPPLPSPP	KMT2B	431	Q9UMN6
PPPAPPPPPAPSPPP	KMT2B	621	Q9UMN6
PGPLPPPPPPPPPVP	PELP1	836	Q8IZL8
PPPPPPPPPPPPGLS	HOXB4	76	P17483
PLPPPPPPPPPPLLP	NRXN2	21	P58401
PLPPPPPISPPSPPP	PCDH15	1746	Q96QU1
PPAPPLPPPAPPLPP	C6orf132	391	Q5T0Z8
PPPPPPPPPQLPQPP	HTT	41	P42858
PPPPPPPLPPPVPCA	GRID2IP	796	A4D2P6
PPPPPLPPLPPLPPQ	DMRTB1	266	Q96MA1
LPLPPPPAPPLPPPP	FMNL3	516	Q8IVF7
PPAPPLPPPPPPLPD	FMNL3	521	Q8IVF7
APPLPPLPPPPGPPP	GLIS3	291	Q8NEA6
PQPPPGPPPPPPPPL	FOXK1	46	P85037
GPVTPPMPPPPPPPP	FMNL2	546	Q96PY5
EPPPQPPPPPPPTPP	MARCHF11	21	A6NNE9
PPPPPPPTPPPGEPA	MARCHF11	26	A6NNE9
PGDLPPPPPPPPPPP	FMNL1	581	O95466
VPPPPPPPPPPPGGP	FMNL1	601	O95466
LPPVPPPPPPPPPTK	ENO4	191	A6NNW6
PPPPGPPPPPPLPST	ENAH	331	Q8N8S7
PPPPPPLPSTGPPPP	ENAH	336	Q8N8S7
PLPSTGPPPPPPPPP	ENAH	341	Q8N8S7
PPPPPPPPAPPLPAS	ENAH	361	Q8N8S7
PARAAPPPPPPPPPP	PPP3CB	6	P16298
PPPPPPPPPPPGADR	PPP3CB	11	P16298
STPAPPPPPPPPPPP	SALL2	156	Q9Y467
APPPPPPPPPPLAAP	HS3ST4	6	Q9Y661
QAAPPPPPPPPPPPP	MICAL2	1716	O94851
PPPPPPPPPPPPTAG	MICAL2	1721	O94851
QMPPPPPPPPPPPPA	IRS4	626	O14654
AMEEPPPPPPPPPPP	MAP3K4	21	Q9Y6R4
PPPPPPPPPPPEPET	MAP3K4	26	Q9Y6R4
LPPPLAPLPPPPPPP	SKOR1	571	P84550
MPPPPPPPPESPPPP	FNBP4	711	Q8N3X1
PPPPPPPPAPKMPPP	FNBP4	911	Q8N3X1
APLPQPPPPPPPPPP	MEX3C	16	Q5U5Q3
SVPPPPPPPPPLPPP	SHTN1	351	A0MZ66
PPPPPPLPPPPPNPI	SHTN1	356	A0MZ66
LPPPPGFPPLPPPPP	SETD1B	681	Q9UPS6
GFPPLPPPPPPPPPQ	SETD1B	686	Q9UPS6
PPPPPPPPPQPGFPM	SETD1B	691	Q9UPS6
PGFPMPPPLPPPPPP	SETD1B	701	Q9UPS6
PPPLPPPPPPPPPAH	SETD1B	706	Q9UPS6
PPPPLPAPPGVPPPP	SETD1B	726	Q9UPS6
APPPPLPPQPPPPPP	SETD1B	1581	Q9UPS6
MPVPPPPPPPLPPPP	WIPF3	1	A6NGB9
PPPPPLPPPPPPLGA	WIPF3	6	A6NGB9
LPPPPPPLGAPPPPP	WIPF3	11	A6NGB9
VPAPPPPTPPPPPPP	WIPF3	171	A6NGB9
PPTPPPPPPPLPPPL	WIPF3	176	A6NGB9
APPVPCAPPPPPPPP	WIPF3	216	A6NGB9
CAPPPPPPPPPPTPP	WIPF3	221	A6NGB9
PPPPPPPTPPPLPPA	WIPF3	226	A6NGB9
LSLPPPPPPPPPPPP	WHAMM	636	Q8TF30
MTPPPPPPPPPGPDP	ESRP2	1	Q9H6T0
GAPQPPPPPPPPPPP	PRR12	831	Q9ULL5
PPPPPPPPPPMPLQL	PRR12	836	Q9ULL5
PPPPPPPPPAPASEP	PRR12	1041	Q9ULL5
PPPPPPPPQPALPSP	PRR12	1471	Q9ULL5
PTPSSPPPPPLPPPP	PRR12	1491	Q9ULL5
PPPPPLPPPPPPAMP	PRR12	1496	Q9ULL5
LPPPPPPAMPSPPPP	PRR12	1501	Q9ULL5
PLQPPPPPPPPPPGL	SF3B2	101	Q13435
SAPPPPPARPPPPPP	USP51	121	Q70EK9
PPPPPPPPPPAPRPR	USP51	131	Q70EK9
ETPPPPPPPPPLPPA	ZFHX4	1956	Q86UP3
PPPPPPLPPAPPQPS	ZFHX4	1961	Q86UP3
QAPPPTPPPPPPPPP	ZFHX4	1991	Q86UP3
QTPPPPPPPPPPPPS	ZFHX4	3111	Q86UP3
TQPPPPPPPPPPLPP	ZNF341	176	Q9BYN7
KPAPKPPPPPPLPPP	ZBTB12	161	Q9Y330
GAPAPPPPPPPPPPA	SEMA4G	761	Q9NTN9
PSPPPPPPPPAPPAP	SCAF1	206	Q9H7N4
QPLPPPPPPPPPPPY	RNF44	286	Q7L0R7
LTPPPPPPPPPPAPE	WASH2P	301	Q6VEQ5
PPPPPPPPPPAPEVL	WASH4P	316	A8MWX3
PPTPLPPPPPPPPGL	PRRG2	161	O14669
LTPPPPPPPPPPAPE	WASHC1	301	A8K0Z3
PPPPPPPPPPAPEVL	WASH3P	301	C4AMC7
PPTPPPPTLPPPIPP	ZBTB4	981	Q9P1Z0
PPPPPPPPPAAPLPP	PXK	516	Q7Z7A4
APPPPPPPSRPGPPP	WIPF1	306	O43516
MSQPPPPPPPLPPPP	VCPIP1	1	Q96JH7
PPPPPLPPPPPPPEA	VCPIP1	6	Q96JH7
PPPPPPPLPPLPLPP	FASLG	56	P48023
KVTPPPPPPPPPPPP	ZNF827	326	Q17R98
RPPPPPPPPAPPRPP	TPRN	156	Q4KMQ1
PPVPPPLPPPTPLPP	ZNF526	171	Q8TF50
STPPPPVPPPPPPPA	WASF1	346	Q92558
QGLPPPPPPPPLPPP	WASF1	421	Q92558
VAPPPPPPPPPPPGP	WASL	371	O00401
MPIPPPPPPPPGPPP	WIPF2	1	Q8TF74
PPPLPHPPPPLPPPP	TRIM66	461	O15016
APVPAPPPPPPPPPP	TRRAP	501	Q9Y4A5
PPPPPPPPPPPVIPH	ZNF318	1446	Q5VUA4
PLPPGAPPPPPPPPP	SF1	576	Q15637
PPPPPPPPPPPPRSR	ZFTA	561	C9JLR9
PPPPPPPPPPLPAAP	ZFHX3	2041	Q15911
PPPPPGPPPPPGLPP	VASP	176	P50552
PAPPAPPPPPPPVVP	ZNF628	266	Q5EBL2
PPPAPPLPPTPSPPP	ZIC5	151	Q96T25
PLPPTPSPPPPPPPP	ZIC5	156	Q96T25
PSPPPPPPPPPPPAL	ZIC5	161	Q96T25
LAGLPPPPPPPPPPP	ZIC5	406	Q96T25
PPPPPPPPPPQLPPE	TRERF1	561	Q96PN7
YSLPPPPPPPPLPPP	NAF1	466	Q96HR8
PPPPPPPPPPRPVLP	MYPOP	311	Q86VE0