Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction6-phosphofructo-2-kinase activity

PFKFB1 PFKFB2 PFKFB3 PFKFB4

8.42e-114624GO:0003873
GeneOntologyMolecularFunctionfructose-2,6-bisphosphate 2-phosphatase activity

PFKFB1 PFKFB2 PFKFB3 PFKFB4

4.20e-105624GO:0004331
GeneOntologyMolecularFunctionphosphofructokinase activity

PFKFB1 PFKFB2 PFKFB3 PFKFB4

2.93e-097624GO:0008443
GeneOntologyMolecularFunctionsugar-phosphatase activity

PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.74e-0810624GO:0050308
GeneOntologyMolecularFunctioncarbohydrate phosphatase activity

PFKFB1 PFKFB2 PFKFB3 PFKFB4

2.74e-0811624GO:0019203
GeneOntologyMolecularFunctioncarbohydrate kinase activity

PFKFB1 PFKFB2 PFKFB3 PFKFB4

4.85e-0721624GO:0019200
GeneOntologyMolecularFunctiontranscription corepressor activity

TOB1 MTA3 RERE EZH1 ARID5A

7.22e-04229625GO:0003714
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

EEF2KMT ASH1L EZH1

1.24e-0368623GO:0016279
GeneOntologyMolecularFunctionphosphoric ester hydrolase activity

ENPP1 PFKFB1 PFKFB2 PFKFB3 PFKFB4 CNP

1.24e-03386626GO:0042578
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

EEF2KMT ASH1L EZH1

1.29e-0369623GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

EEF2KMT ASH1L EZH1

1.40e-0371623GO:0042054
GeneOntologyMolecularFunctionphosphatase activity

ENPP1 PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.96e-03287625GO:0016791
GeneOntologyMolecularFunctioncyclic-nucleotide phosphodiesterase activity

ENPP1 CNP

3.17e-0327622GO:0004112
GeneOntologyMolecularFunctionscavenger receptor activity

ENPP1 CD36

3.17e-0327622GO:0005044
GeneOntologyBiologicalProcessfructose 2,6-bisphosphate metabolic process

PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.10e-096624GO:0006003
GeneOntologyBiologicalProcessfructose metabolic process

PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.31e-0716624GO:0006000
GeneOntologyBiologicalProcessnucleotide catabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP CNP VCP

1.98e-07208628GO:0009166
GeneOntologyBiologicalProcessnucleoside phosphate catabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP CNP VCP

2.64e-07216628GO:1901292
GeneOntologyBiologicalProcesscarbohydrate phosphorylation

PFKFB1 PFKFB2 PFKFB3 PFKFB4

8.93e-0725624GO:0046835
GeneOntologyBiologicalProcessADP catabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP

1.19e-06114626GO:0046032
GeneOntologyBiologicalProcesspurine nucleoside diphosphate catabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP

1.39e-06117626GO:0009137
GeneOntologyBiologicalProcesspurine ribonucleoside diphosphate catabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP

1.39e-06117626GO:0009181
GeneOntologyBiologicalProcessADP metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP

1.61e-06120626GO:0046031
GeneOntologyBiologicalProcessribonucleoside diphosphate catabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP

1.69e-06121626GO:0009191
GeneOntologyBiologicalProcessorganophosphate catabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP CNP VCP

1.92e-06281628GO:0046434
GeneOntologyBiologicalProcessnucleoside diphosphate catabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP

1.95e-06124626GO:0009134
GeneOntologyBiologicalProcesspurine nucleoside diphosphate metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP

2.81e-06132626GO:0009135
GeneOntologyBiologicalProcesspurine ribonucleoside diphosphate metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP

2.81e-06132626GO:0009179
GeneOntologyBiologicalProcessribonucleoside diphosphate metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP

4.46e-06143626GO:0009185
GeneOntologyBiologicalProcessnucleoside diphosphate metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP

5.66e-06149626GO:0009132
GeneOntologyBiologicalProcesspurine ribonucleotide catabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP

1.16e-05169626GO:0009154
GeneOntologyBiologicalProcessATP metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP VCP

1.18e-05257627GO:0046034
GeneOntologyBiologicalProcessribonucleotide catabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP

1.56e-05178626GO:0009261
GeneOntologyBiologicalProcesspurine nucleotide catabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP

1.77e-05182626GO:0006195
GeneOntologyBiologicalProcessglycolytic process

ENPP1 PFKFB1 PFKFB2 PFKFB3 APP

2.00e-05110625GO:0006096
GeneOntologyBiologicalProcesspurine-containing compound catabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP

2.13e-05188626GO:0072523
GeneOntologyBiologicalProcessregulation of purine nucleotide metabolic process

ENTPD1 PFKFB1 APP VCP RD3

2.18e-05112625GO:1900542
GeneOntologyBiologicalProcesspurine ribonucleoside triphosphate metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP VCP

2.19e-05283627GO:0009205
GeneOntologyBiologicalProcessregulation of nucleotide metabolic process

ENTPD1 PFKFB1 APP VCP RD3

2.28e-05113625GO:0006140
GeneOntologyBiologicalProcessribonucleoside triphosphate metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP VCP

2.56e-05290627GO:0009199
GeneOntologyBiologicalProcesspurine nucleoside triphosphate metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP VCP

2.62e-05291627GO:0009144
GeneOntologyBiologicalProcesspyridine nucleotide catabolic process

ENPP1 PFKFB1 PFKFB2 PFKFB3 APP

2.92e-05119625GO:0019364
GeneOntologyBiologicalProcessnicotinamide nucleotide metabolic process

ENPP1 PFKFB1 PFKFB2 PFKFB3 APP VCP

3.19e-05202626GO:0046496
GeneOntologyBiologicalProcesspyridine nucleotide metabolic process

ENPP1 PFKFB1 PFKFB2 PFKFB3 APP VCP

3.19e-05202626GO:0019362
GeneOntologyBiologicalProcesspyridine-containing compound catabolic process

ENPP1 PFKFB1 PFKFB2 PFKFB3 APP

3.43e-05123625GO:0072526
GeneOntologyBiologicalProcessnucleoside triphosphate metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP VCP

3.69e-05307627GO:0009141
GeneOntologyBiologicalProcessnucleobase-containing compound catabolic process

TOB1 SLC11A1 ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP CNP VCP

3.95e-056966210GO:0034655
GeneOntologyBiologicalProcesspyridine-containing compound metabolic process

ENPP1 PFKFB1 PFKFB2 PFKFB3 APP VCP

3.96e-05210626GO:0072524
GeneOntologyBiologicalProcesscarbohydrate derivative catabolic process

PGLYRP4 ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP

5.09e-05323627GO:1901136
GeneOntologyBiologicalProcesslipoprotein particle mediated signaling

CD36 APP

5.31e-054622GO:0055095
GeneOntologyBiologicalProcesslow-density lipoprotein particle mediated signaling

CD36 APP

5.31e-054622GO:0055096
GeneOntologyBiologicalProcesspyruvate metabolic process

ENPP1 PFKFB1 PFKFB2 PFKFB3 APP

6.80e-05142625GO:0006090
GeneOntologyBiologicalProcessnegative regulation of purine nucleotide biosynthetic process

ENTPD1 RD3

8.84e-055622GO:1900372
GeneOntologyBiologicalProcessnegative regulation of nucleotide biosynthetic process

ENTPD1 RD3

8.84e-055622GO:0030809
GeneOntologyBiologicalProcessnegative regulation of purine nucleotide metabolic process

ENTPD1 PFKFB1 RD3

1.21e-0432623GO:1900543
GeneOntologyBiologicalProcesscarbohydrate metabolic process

MAN2A1 ENPP1 GBE1 PFKFB1 PFKFB2 PFKFB3 PFKFB4 APP SLC23A1

1.26e-04646629GO:0005975
GeneOntologyBiologicalProcessnegative regulation of nucleotide metabolic process

ENTPD1 PFKFB1 RD3

1.32e-0433623GO:0045980
GeneOntologyBiologicalProcesspurine-containing compound metabolic process

SLC17A1 ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP VCP RD3

1.35e-04652629GO:0072521
GeneOntologyBiologicalProcesscytokine production involved in immune response

TRIL SLC11A1 CD36 ASH1L ARID5A

1.50e-04168625GO:0002367
GeneOntologyBiologicalProcesstype II interferon production

PGLYRP4 SLC11A1 ENPP1 APP ARID5A

1.54e-04169625GO:0032609
GeneOntologyBiologicalProcessregulation of ATP metabolic process

ENTPD1 PFKFB1 APP VCP

1.63e-0491624GO:1903578
GeneOntologyBiologicalProcessnucleotide metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP CNP VCP RD3

1.94e-04684629GO:0009117
GeneOntologyBiologicalProcessnucleoside phosphate metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP CNP VCP RD3

2.09e-04691629GO:0006753
GeneOntologyBiologicalProcessregulation of purine nucleotide biosynthetic process

ENTPD1 VCP RD3

2.36e-0440623GO:1900371
GeneOntologyBiologicalProcessregulation of nucleotide biosynthetic process

ENTPD1 VCP RD3

2.36e-0440623GO:0030808
GeneOntologyBiologicalProcesscarbohydrate catabolic process

ENPP1 PFKFB1 PFKFB2 PFKFB3 APP

3.07e-04196625GO:0016052
GeneOntologyBiologicalProcessmonosaccharide metabolic process

MAN2A1 PFKFB1 PFKFB2 PFKFB3 PFKFB4 SLC23A1

3.33e-04310626GO:0005996
GeneOntologyBiologicalProcesspositive regulation of ATP metabolic process

PFKFB1 APP VCP

4.06e-0448623GO:1903580
GeneOntologyBiologicalProcessnucleobase-containing small molecule metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP CNP VCP RD3

4.50e-04767629GO:0055086
GeneOntologyBiologicalProcessurate transport

SLC17A1 SLC23A1

4.80e-0411622GO:0015747
GeneOntologyBiologicalProcesspurine nucleotide metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP VCP RD3

5.10e-04619628GO:0006163
GeneOntologyBiologicalProcessorganophosphate metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 PFKFB4 APP PIK3R5 CNP VCP RD3

5.37e-0411426211GO:0019637
GeneOntologyBiologicalProcesspositive regulation of nucleotide metabolic process

PFKFB1 APP VCP

6.07e-0455623GO:0045981
GeneOntologyBiologicalProcesspositive regulation of purine nucleotide metabolic process

PFKFB1 APP VCP

6.07e-0455623GO:1900544
GeneOntologyBiologicalProcessprotein-DNA complex organization

EEF2KMT MTA3 VPS72 ASH1L MCMDC2 PIWIL2 RERE APP EZH1 TRRAP

7.37e-049996210GO:0071824
GeneOntologyBiologicalProcesspurine ribonucleotide metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP VCP

8.42e-04512627GO:0009150
GeneOntologyBiologicalProcessimmune effector process

TRIL MASP1 CD1E PGLYRP4 SLC11A1 ENPP1 CD36 APP ARID5A

1.01e-03859629GO:0002252
GeneOntologyBiologicalProcessgeneration of precursor metabolites and energy

ENPP1 GBE1 PFKFB1 PFKFB2 PFKFB3 APP VCP

1.02e-03529627GO:0006091
GeneOntologyBiologicalProcessribonucleotide metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP VCP

1.06e-03533627GO:0009259
GeneOntologyBiologicalProcessribose phosphate metabolic process

ENPP1 ENTPD1 PFKFB1 PFKFB2 PFKFB3 APP VCP

1.15e-03540627GO:0019693
GeneOntologyBiologicalProcessnegative regulation of protein localization

FRMD4A CD36 APP ERLEC1 VCP

1.16e-03263625GO:1903828
GeneOntologyBiologicalProcessregulation of type II interferon production

PGLYRP4 SLC11A1 APP ARID5A

1.22e-03155624GO:0032649
GeneOntologyBiologicalProcessproduction of molecular mediator of immune response

TRIL SLC11A1 ENPP1 CD36 ASH1L ARID5A

1.31e-03403626GO:0002440
GeneOntologyBiologicalProcessspontaneous synaptic transmission

DOC2A APP

1.32e-0318622GO:0098814
GeneOntologyBiologicalProcessmicroglia differentiation

ENPP1 APP

1.32e-0318622GO:0014004
GeneOntologyBiologicalProcesschromatin organization

EEF2KMT MTA3 VPS72 ASH1L PIWIL2 RERE APP EZH1 TRRAP

1.36e-03896629GO:0006325
GeneOntologyBiologicalProcesscytokine production

TRIL PGLYRP4 SLC11A1 ENPP1 DTX4 CD36 ASH1L APP ARID5A ZNF287

1.44e-0310916210GO:0001816
GeneOntologyBiologicalProcesschromatin remodeling

EEF2KMT MTA3 VPS72 ASH1L PIWIL2 RERE APP EZH1

1.63e-03741628GO:0006338
GeneOntologyBiologicalProcesshexose metabolic process

MAN2A1 PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.63e-03284625GO:0019318
GeneOntologyBiologicalProcesspositive regulation of T-helper 1 type immune response

SLC11A1 ARID5A

1.63e-0320622GO:0002827
GeneOntologyBiologicalProcessregulation of generation of precursor metabolites and energy

ENPP1 PFKFB1 APP VCP

1.68e-03169624GO:0043467
MousePhenoincreased variability of skeletal muscle fiber size

FLNC SCYL1 APP VCP

1.75e-0543514MP:0009403
MousePhenodecreased cardiac muscle glycogen level

CD36 GBE1

3.91e-053512MP:0014072
Domain6Pfruct_kin

PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.10e-104624IPR003094
Domain6Phosfructo_kin

PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.10e-104624IPR013079
Domain6PF2K

PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.10e-104624PF01591
DomainPG/BPGM_mutase_AS

PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.37e-089624IPR001345
DomainPGAM

PFKFB1 PFKFB2 PFKFB3 PFKFB4

2.28e-0810624SM00855
DomainPG_MUTASE

PFKFB1 PFKFB2 PFKFB3 PFKFB4

2.28e-0810624PS00175
DomainHis_Phos_1

PFKFB1 PFKFB2 PFKFB3 PFKFB4

5.34e-0812624PF00300
DomainHis_Pase_superF_clade-1

PFKFB1 PFKFB2 PFKFB3 PFKFB4

5.34e-0812624IPR013078
DomainHis_PPase_superfam

PFKFB1 PFKFB2 PFKFB3 PFKFB4

5.12e-0720624IPR029033
Domain-

PFKFB1 PFKFB2 PFKFB3 PFKFB4

5.12e-07206243.40.50.1240
DomainBAH

MTA3 ASH1L RERE

5.64e-0611623SM00439
DomainBAH

MTA3 ASH1L RERE

5.64e-0611623PF01426
DomainBAH

MTA3 ASH1L RERE

5.64e-0611623PS51038
DomainBAH_dom

MTA3 ASH1L RERE

5.64e-0611623IPR001025
DomainSANT

MTA3 RERE EZH1

6.11e-0450623SM00717
DomainSANT/Myb

MTA3 RERE EZH1

6.86e-0452623IPR001005
DomainZnF_GATA

MTA3 RERE

7.00e-0412622SM00401
DomainELM2

MTA3 RERE

8.26e-0413622PF01448
DomainELM2

MTA3 RERE

8.26e-0413622PS51156
DomainELM2_dom

MTA3 RERE

8.26e-0413622IPR000949
DomainELM2

MTA3 RERE

8.26e-0413622SM01189
Domain-

MAN2A1 GBE1

9.62e-04146222.60.40.1180
DomainGlyco_hydro_b

MAN2A1 GBE1

1.11e-0315622IPR013780
DomainZnf_GATA

MTA3 RERE

1.11e-0315622IPR000679
DomainGATA

MTA3 RERE

1.11e-0315622PF00320
DomainGATA_ZN_FINGER_1

MTA3 RERE

1.26e-0316622PS00344
DomainGATA_ZN_FINGER_2

MTA3 RERE

1.26e-0316622PS50114
DomainEz/rad/moesin-like

FRMD4A EPB41L5

2.19e-0321622IPR000798
DomainFERM_CS

FRMD4A EPB41L5

2.85e-0324622IPR019747
DomainFERM_C

FRMD4A EPB41L5

3.35e-0326622PF09380
DomainSANT_dom

MTA3 RERE

3.35e-0326622IPR017884
DomainFERM_C

FRMD4A EPB41L5

3.61e-0327622SM01196
DomainFERM_PH-like_C

FRMD4A EPB41L5

3.61e-0327622IPR018980
DomainSANT

MTA3 RERE

3.88e-0328622PS51293
DomainFERM_N

FRMD4A EPB41L5

5.36e-0333622PF09379
DomainFERM_N

FRMD4A EPB41L5

5.36e-0333622IPR018979
DomainMyb_DNA-binding

MTA3 RERE

6.01e-0335622PF00249
PathwayREACTOME_REGULATION_OF_GLYCOLYSIS_BY_FRUCTOSE_2_6_BISPHOSPHATE_METABOLISM

PFKFB1 PFKFB2 PFKFB3 PFKFB4

6.79e-0812504M27950
PathwayKEGG_FRUCTOSE_AND_MANNOSE_METABOLISM

PFKFB1 PFKFB2 PFKFB3 PFKFB4

6.00e-0634504M15898
PathwayREACTOME_GLUCOSE_METABOLISM

PFKFB1 PFKFB2 PFKFB3 PFKFB4

2.00e-0482504MM15394
PathwayREACTOME_GLUCOSE_METABOLISM

PFKFB1 PFKFB2 PFKFB3 PFKFB4

2.29e-0485504M1870
Pubmed

Expression of human placental-type 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase in various cells and cell lines.

PFKFB1 PFKFB2 PFKFB3 PFKFB4

9.77e-1246349464277
Pubmed

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: a metabolic signaling enzyme.

PFKFB1 PFKFB2 PFKFB3 PFKFB4

9.77e-1246347574501
Pubmed

Cloning, expression and chromosomal localization of a human testis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene.

PFKFB1 PFKFB2 PFKFB3 PFKFB4

9.77e-12463410095107
Pubmed

Molecular cloning, sequence analysis, and expression of a human liver cDNA coding for fructose-6-P,2-kinase:fructose-2,6-bisphosphatase.

PFKFB1 PFKFB2 PFKFB3 PFKFB4

9.77e-1246342837207
Pubmed

The kinase activity of human brain 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase is regulated via inhibition by phosphoenolpyruvate.

PFKFB1 PFKFB2 PFKFB3 PFKFB4

3.41e-10763415896703
Pubmed

Lactate downregulates the glycolytic enzymes hexokinase and phosphofructokinase in diverse tissues from mice.

PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.22e-09963421074528
Pubmed

Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene family (PFKFB-1-4) expression in vivo.

PFKFB2 PFKFB3 PFKFB4

5.66e-09363314623077
Pubmed

Increased expression and phosphorylation of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoforms in urinary exosomes in pre-eclampsia.

PFKFB2 PFKFB3 PFKFB4

5.66e-09363330819197
Pubmed

PFKFB4 interacts with FBXO28 to promote HIF-1α signaling in glioblastoma.

PFKFB2 PFKFB3 PFKFB4

3.15e-07863336115843
Pubmed

A high content drug screen identifies ursolic acid as an inhibitor of amyloid beta protein interactions with its receptor CD36.

CD36 APP

3.23e-06263221835916
Pubmed

Splice isoforms of ubiquitous 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in human brain.

PFKFB2 PFKFB3

3.23e-06263211245921
Pubmed

Cardiac expression of kinase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase inhibits glycolysis, promotes hypertrophy, impairs myocyte function, and reduces insulin sensitivity.

PFKFB1 PFKFB2

3.23e-06263215331593
Pubmed

Loss of PFKFB4 induces cell death in mitotically arrested ovarian cancer cells.

PFKFB3 PFKFB4

3.23e-06263228152500
Pubmed

Intercellular adhesion molecule-4 and CD36 are implicated in the abnormal adhesiveness of sickle cell SAD mouse erythrocytes to endothelium.

CD36 ICAM4

3.23e-06263220015873
Pubmed

E-NTPDase and E-ADA activities are altered in lymphocytes of patients with indeterminate form of Chagas' disease.

ENPP1 ENTPD1

3.23e-06263222846899
Pubmed

Expression of Pfkfb isoenzymes during in vitro differentiation of mouse embryonic stem cells into insulin-producing cells.

PFKFB2 PFKFB3

3.23e-06263238813509
Pubmed

Cloning of cDNA encoding for a novel isozyme of fructose 6-phosphate, 2-kinase/fructose 2,6-bisphosphatase from human placenta.

PFKFB3 PFKFB4

3.23e-0626328830046
Pubmed

Overexpression of ubiquitous 6-phosphofructo-2-kinase in the liver of transgenic mice results in weight gain.

PFKFB2 PFKFB3

3.23e-06263217991424
Pubmed

CD36 overexpression in human brain correlates with beta-amyloid deposition but not with Alzheimer's disease.

CD36 APP

3.23e-06263215059642
Pubmed

Overexpression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4 in the human breast and colon malignant tumors.

PFKFB2 PFKFB4

3.23e-06263215925437
Pubmed

Identification of nucleotide pyrophosphatase/alkaline phosphodiesterase I activity associated with the mouse plasma cell differentiation antigen PC-1.

ENPP1 CNP

3.23e-0626321647027
Pubmed

NPP1 is responsible for potent extracellular ATP hydrolysis as NTPDase1 in primary cultured murine microglia.

ENPP1 ENTPD1

3.23e-06263229516286
Pubmed

Molecular cloning and tissue-specific expression of mouse kidney 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

PFKFB1 PFKFB2

3.23e-0626328814283
Pubmed

Splice isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4: expression and hypoxic regulation.

PFKFB3 PFKFB4

3.23e-06263216311927
Pubmed

Immunohistochemical analysis of transporters related to clearance of amyloid-β peptides through blood-cerebrospinal fluid barrier in human brain.

CD36 APP

3.23e-06263226449856
Pubmed

Nucleoside triphosphate diphosphohydrolase-1 ectonucleotidase is required for normal vas deferens contraction and male fertility through maintaining P2X1 receptor function.

P2RX1 ENTPD1

3.23e-06263225160621
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MTA3 VPS72 CCNB3 TPRN ASH1L RERE APP EZH1 SOWAHC TRRAP VCP

4.72e-061116631131753913
Pubmed

Selenoprotein S is required for clearance of C99 through endoplasmic reticulum-associated degradation.

APP VCP

9.68e-06363228315680
Pubmed

Amyloid-β inhibits No-cGMP signaling in a CD36- and CD47-dependent manner.

CD36 APP

9.68e-06363221203512
Pubmed

Vitamin A regulates genes involved in hepatic gluconeogenesis in mice: phosphoenolpyruvate carboxykinase, fructose-1,6-bisphosphatase and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

PFKFB1 PFKFB2

9.68e-0636329202079
Pubmed

Hypoxic regulation of PFKFB-3 and PFKFB-4 gene expression in gastric and pancreatic cancer cell lines and expression of PFKFB genes in gastric cancers.

PFKFB3 PFKFB4

9.68e-06363217143338
Pubmed

[EXPRESSION OF PFKFB, HK2, NAMPT, TSPAN13 AND HSPB8 GENES IN PEDIATRIC GLIOMA].

PFKFB3 PFKFB4

1.93e-05463227491149
Pubmed

Characterization of glucokinase-binding protein epitopes by a phage-displayed peptide library. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel interaction partner.

PFKFB1 PFKFB2

1.93e-05463211522786
Pubmed

Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks.

APP TRRAP

1.93e-05463219282473
Pubmed

[EXPRESSION OF GENES, WHICH CONTROL GLUCOSE METABOLISM, IN BLOOD CELLS OF THE OBESE BOYS WITH INSULIN RESISTANCE].

PFKFB1 PFKFB3

1.93e-05463226827442
Pubmed

Hnrnpk maintains chondrocytes survival and function during growth plate development via regulating Hif1α-glycolysis axis.

PFKFB2 PFKFB3 PFKFB4

2.46e-053163336127325
Pubmed

Prediction and verification of the AD-FTLD common pathomechanism based on dynamic molecular network analysis.

APP VCP

3.22e-05563234385591
Pubmed

A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells.

PFKFB2 PFKFB3

3.22e-05563218039179
Pubmed

A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.

CD36 APP

3.22e-05563212239221
Pubmed

Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease.

APP CNP

4.82e-05663237258678
Pubmed

Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.

VPS72 PNN TRRAP

6.18e-054263335705031
Pubmed

TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.

CD36 APP

6.74e-05763229518356
Pubmed

Downregulated expression of lactate dehydrogenase in adult oligodendrocytes and its implication for the transfer of glycolysis products to axons.

APP CNP

6.74e-05763238587131
Pubmed

Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1.

PFKFB3 PFKFB4

1.44e-041063225974097
Pubmed

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.

CD36 APP

1.76e-041163220037584
Pubmed

Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma.

FLNC TRRAP

1.76e-041163224349473
Pubmed

Quantification of synapse formation and maintenance in vivo in the absence of synaptic release.

DOC2A VCP

2.49e-041363215145078
Pubmed

Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.

ASH1L TRRAP

2.90e-041463228263302
Pubmed

A genome-wide association study of optic disc parameters.

SCYL1 RERE

2.90e-041463220548946
Pubmed

In vitro nuclear interactome of the HIV-1 Tat protein.

MTA3 PNN PES1 TRRAP

4.41e-0419563419454010
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

FLNC PNN PFKFB2 PFKFB3 CNP VCP

4.87e-0455163634728620
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

MAN2A1 ENPP1 PES1 GBE1 APP TRRAP ERLEC1 CNP VCP

5.24e-04129763933545068
Pubmed

The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes.

VPS72 TRRAP

5.41e-041963215647280
Pubmed

Identification of ERAD components essential for dislocation of the null Hong Kong variant of α-1-antitrypsin (NHK).

ERLEC1 VCP

5.41e-041963225660456
Pubmed

Identification of type 2 diabetes-associated combination of SNPs using support vector machine.

SLC11A1 CD36 ICAM4

6.14e-049163320416077
Pubmed

H2A.Z.2.2 is an alternatively spliced histone H2A.Z variant that causes severe nucleosome destabilization.

VPS72 TRRAP

6.63e-042163222467210
Pubmed

Unassembled CD147 is an endogenous endoplasmic reticulum-associated degradation substrate.

ERLEC1 VCP

6.63e-042163223097496
Pubmed

CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism.

EZH1 TRRAP

7.97e-042363231281901
Pubmed

Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

VPS72 TRRAP

7.97e-042363214966270
Pubmed

Functional genomics identifies therapeutic targets for MYC-driven cancer.

PES1 SCYL1 TRRAP

8.80e-0410363322623531
Pubmed

Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.

FLNC SCYL1 APP SOWAHC

8.86e-0423563428378594
Pubmed

Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation.

DOC2A VCP

9.43e-042563215935055
Pubmed

Capillary endothelial fatty acid binding proteins 4 and 5 play a critical role in fatty acid uptake in heart and skeletal muscle.

CD36 PFKFB3

9.43e-042563223968980
Pubmed

Obesity-related polymorphisms and their associations with the ability to regulate fat oxidation in obese Europeans: the NUGENOB study.

ENPP1 CD36

9.43e-042563219876004
Pubmed

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

MTA3 TRRAP

1.10e-032763223395962
Pubmed

TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.

TRRAP VCP

1.18e-032863229653964
Pubmed

E-cadherin expression on multiple myeloma cells activates tumor-promoting properties in plasmacytoid DCs.

TPRN PES1

1.18e-032863230277474
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

PNN TPRN PES1 PFKFB3 CNP VCP

1.24e-0366063632780723
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

UBE2E2 MTA3 ENTPD1 ASH1L PFKFB1 RERE PFKFB4 APP TRRAP

1.39e-03148963928611215
Pubmed

Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.

ENPP1 PFKFB1 PFKFB3 VCP

1.46e-0326963430442662
Pubmed

Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.

MASP1 APP

1.55e-033263218842294
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

MTA3 VPS72 ENTPD1 GBE1 HMGXB3 PFKFB4 TRRAP ZNF287

1.75e-03124263830973865
InteractionPFKFB1 interactions

PFKFB1 PFKFB3 PFKFB4 APP

1.08e-0626614int:PFKFB1
InteractionPFKFB3 interactions

PES1 PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.80e-0667615int:PFKFB3
InteractionPFKFB4 interactions

PFKFB1 PFKFB2 PFKFB3 PFKFB4

5.19e-0638614int:PFKFB4
GeneFamily6-phosphofructo-2-kinases/fructose-2,6-biphosphatases

PFKFB1 PFKFB2 PFKFB3 PFKFB4

4.01e-1144741077
GeneFamilyOlfactory receptors, family 52

OR52I2 OR52W1 OR52N1

2.79e-0449473165
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MTA3 RERE EZH1

3.52e-0453473532
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MTA3 RERE

6.80e-041547282
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

ASH1L EZH1

3.52e-0334472487
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

FRMD4A EPB41L5

7.48e-03504721293
CoexpressionGSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_DN

UBE2E2 P2RX1 WWC3 ENPP1 APP TOP3A

6.77e-06198616M9234
CoexpressionAtlasMyeloid Cells, DC.8+.SLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3

FRMD4A SLC11A1 CD36 ENTPD1 PFKFB3 APP SOWAHC STRIP2

1.93e-05425588GSM538255_500
CoexpressionAtlasMyeloid Cells, MF.Thio5.II-480hi.PC, CD115+ MHC II- F480hi Siglec F-, Peritoneal Cavity, avg-3

FAM234A SLC11A1 P2RX1 ENPP1 CD36 ENTPD1 GBE1 APP

2.51e-05441588GSM605862_500
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|normal_Lymph_Node / Location, Cell class and cell subclass

CFAP251 P2RX1 DTX4 PFKFB2 PFKFB3 APP

1.86e-07176636476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P2RX1 CCNB3 PFKFB3 PIK3R5 STRIP2

4.27e-0617063517bd7fd25a2657cb536ad47e294332920f759e95
ToppCellControl-APC-like-Dendritic_cells|Control / group, cell type (main and fine annotations)

CD1E ENPP1 ENTPD1 PFKFB3 PIK3R5

6.12e-061836358f9c8e2436f18ea7c265b08e4e149e19cb513a16
ToppCellControl-APC-like|Control / group, cell type (main and fine annotations)

CD1E ENPP1 ENTPD1 PFKFB3 PIK3R5

6.12e-06183635c313ac72cc9fa1583456d452393f61f0a4ca33a8
ToppCellNS-moderate-d_0-4-Myeloid-Non-resident_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SLC11A1 P2RX1 PFKFB3 PIK3R5 ARID5A

6.80e-06187635fcc32dbc9c5ae6176f154715a3e73aa32d78ad64
ToppCellFetal_29-31_weeks-Immune-monocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC11A1 P2RX1 ENTPD1 PFKFB4 PIK3R5

7.34e-06190635ad297172a74a80ed5c10f921e15efd1da0fd2d6b
ToppCellhuman_hepatoblastoma-Inflammatory_Monocytes|World / Sample and Cell Type and Tumor Cluster (all cells)

SLC11A1 UBE2E2 ENTPD1 PFKFB3 PIK3R5

7.53e-061916353b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC11A1 P2RX1 ENTPD1 PFKFB3 PIK3R5

8.12e-061946353043f6230fa723037c8cf7123f611ae847b39fd4
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CD1E TOB1 ENTPD1 PFKFB3 PIK3R5

8.12e-06194635bde6830a281f7cd7fd1733e40a41ddd2673ba88e
ToppCellcontrol-Myeloid-Neutrophils_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TOB1 SLC11A1 ENTPD1 PFKFB2 PFKFB3

8.12e-061946352218e6677dc6781a6e4ef3a315f2298cc2cd9df2
ToppCellCOVID-19-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

UBE2E2 P2RX1 CD36 PFKFB2 APP

8.33e-061956354a7c080230ce6a79335ecbeadecb0177b2c13625
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC11A1 CD36 ENTPD1 PFKFB3 PIK3R5

8.75e-061976358af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRMD4A SLC11A1 P2RX1 ENTPD1 PIK3R5

8.75e-06197635d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CD1E TOB1 ENTPD1 PFKFB3 PIK3R5

8.75e-06197635a902aa05e5f711bcfdd9e19749ab636b597eb116
ToppCellsevere-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC11A1 P2RX1 CD36 ENTPD1 PFKFB3

8.97e-06198635d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCellParenchymal-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRMD4A SLC11A1 P2RX1 ENTPD1 PIK3R5

9.19e-061996357ee2805fd9143eba11bf6832267b62189683608b
ToppCellBronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC11A1 P2RX1 ENTPD1 PFKFB3 PIK3R5

9.41e-062006355432bdf495431cd26f6e4cd585100f3652588913
ToppCellBronchial-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRMD4A SLC11A1 P2RX1 ENTPD1 PIK3R5

9.41e-062006352f5b71e55c2de0e77fdae6667eb57f333acc6cd1
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

DOC2A P2RX1 PIWIL2 RERE

2.98e-051256349e98dcfdc768ae492f453efc08926164bbb0a909
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD1E UBE2E2 ENPP1 ENTPD1

8.57e-051646343a4ecc632be003d09b765c992804134348d2278b
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CD1E UBE2E2 ENPP1 ENTPD1

8.57e-051646344b10b78d4d76023c3c5bcd427757218fdd5465ca
ToppCell356C-Epithelial_cells-Epithelial-D_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FRMD4A SLC11A1 ENTPD1 ARID5A

9.63e-05169634818ab7a6fd1940a22d3bd99fe15f0af888af6b3e
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FRMD4A SLC11A1 ENTPD1 SLC23A1

9.63e-051696340867528101767fc65e93b3561480bf830c50368d
ToppCell356C-Epithelial_cells-Epithelial-D_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FRMD4A SLC11A1 ENTPD1 ARID5A

9.63e-05169634f982f2e0d341fa27229f443ebe5c0e4a9e63bda6
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PFKFB3 PIK3R5 SPATA4 STRIP2

1.05e-04173634f0eb48c1283bdde313bb75f6ffc0d2626922d24b
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMD4A MTA3 DTX4 DANCR

1.08e-04174634a9f34d1237f335d27c5560ff514368f4709f9144
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

CFAP251 P2RX1 PFKFB2 APP

1.08e-041746342274648b80dd74f3c948a779bba3391095964c34
ToppCellfacs-Trachea-24m-Hematologic-myeloid|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC11A1 CD36 ENTPD1 PIK3R5

1.08e-041746342f25fba5225f4687df4396645e94565a640b5583
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM234A SLC11A1 APP SOWAHC

1.10e-0417563469b59ec58e64644deb7e07f31ef495ef4a6f6276
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P2RX1 PFKFB3 PIK3R5 STRIP2

1.10e-04175634f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM234A SLC11A1 APP SOWAHC

1.10e-041756344f7498b5a0ed52c348a5f94bcd41d830ba7954ea
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMD4A TPRN ENTPD1 PFKFB4

1.13e-041766348e89471f838ea81235256cc2470f1c12c9b75f8a
ToppCellControl-Myeloid-Dendritic_cells|Control / group, cell type (main and fine annotations)

FRMD4A CD1E ENTPD1 PIK3R5

1.23e-0418063425ad95c3c30e3b82abe93bd77ba003f5c2241f7c
ToppCellCV-Severe-4|Severe / Virus stimulation, Condition and Cluster

UBE2E2 ENTPD1 GBE1 PFKFB4

1.23e-04180634cf84a01e6a33e5d27ad7be1d9069a0370b5116d1
ToppCellSevere-Myeloid-mDC|Severe / Condition, Lineage, Cell class and cell subclass

CD1E UBE2E2 ENPP1 ENTPD1

1.25e-0418163400f2949b609ac21bd2da6fd8f685739eeb2f48ad
ToppCellSevere-Myeloid-mDC-|Severe / Condition, Lineage, Cell class and cell subclass

CD1E UBE2E2 ENPP1 ENTPD1

1.25e-0418163451ded98c76ec35ab1d24ac3ab98280381daa9831
ToppCellCOPD-Myeloid-Mast|World / Disease state, Lineage and Cell class

MAN2A1 P2RX1 STRIP2 RD3

1.28e-0418263468a1e7b804f309bfd6c23d65fad20a9a962712ae
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DANCR PFKFB3 APP CNP

1.36e-041856346da9a06e1514d5d5f47359a14637f02539846096
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DANCR PFKFB3 APP CNP

1.36e-041856344a188e2566a75d1b4f3c879a8c241c277c4b451c
ToppCellCOPD-Myeloid-Mast|COPD / Disease state, Lineage and Cell class

MAN2A1 P2RX1 STRIP2 RD3

1.39e-04186634def6f0f284acc2154738574c8c5d3d2a5ef1f208
ToppCellControl-Lymphoid-B_Plasma|Lymphoid / Disease state, Lineage and Cell class

UBE2E2 P2RX1 LGALSL ERLEC1

1.39e-04186634a08a50bff4e629588faa22440d57334b1df0e8df
ToppCellRA-11._Adipocyte|World / Chamber and Cluster_Paper

FRMD4A GBE1 PFKFB1 PFKFB3

1.45e-041886344dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCellControl-Myeloid-Transitioning_MDM|Control / group, cell type (main and fine annotations)

SLC11A1 ENTPD1 PFKFB3 PIK3R5

1.51e-04190634d6fd8c23cde4a10cc1517b6899a5a855fdfff2e2
ToppCellMS-pDC-|MS / Condition, Cell_class and T cell subcluster

UBE2E2 CD36 PFKFB2 APP

1.51e-04190634f56ec302d556ace4f7609017a35c311cf43aa8a5
ToppCellMS-pDC|MS / Condition, Cell_class and T cell subcluster

UBE2E2 CD36 PFKFB2 APP

1.51e-04190634f41d7ab7d7fbcd73fddb6c3533c6a3e642e3d07f
ToppCellCOPD-Myeloid-cDC2|COPD / Disease state, Lineage and Cell class

CD1E ENTPD1 PFKFB3 PIK3R5

1.54e-041916342af6e4a6bd1f2193ece2131c3b7d976dd23a6966
ToppCellCOPD-Myeloid-cDC2|World / Disease state, Lineage and Cell class

CD1E TOB1 ENTPD1 PFKFB3

1.54e-041916344e4887175200a57e1b041f2f131e3df774df3509
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC11A1 CD36 PFKFB4 PIK3R5

1.54e-0419163447a2afc4102199b4bc76bd01b2967c8016186462
ToppCellCOPD-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

CD1E TOB1 ENTPD1 PFKFB3

1.57e-04192634984cdc2f1d93e164bc946d63f58dacb629f82eb7
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC11A1 CD36 ENTPD1 PFKFB3

1.57e-04192634f14ee74ac3275601749a23c5efe39c2413a62e1a
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Colonocyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOC2A P2RX1 ENPP1 PIWIL2

1.57e-041926341a3d95a9801cc4569b67fa652b2af46c4dedbaef
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMD4A CD36 ENTPD1 APP

1.57e-041926344bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCellIPF-Myeloid-cDC2|IPF / Disease state, Lineage and Cell class

CD1E ENTPD1 PFKFB3 PIK3R5

1.57e-04192634fe1de692fec48cba4a9bbc6eaa257260e8b4e800
ToppCellCD8+_Memory_T_cell-RSV-5|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

UBE2E2 ENTPD1 PFKFB3 PFKFB4

1.57e-041926346357af0fb60a13a0ac727bc922b7606ab520ef5c
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC11A1 CD36 ENTPD1 PFKFB3

1.57e-041926340219093e7921a0db78053aee13ec480b520f5662
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

UBE2E2 SLC17A1 ASH1L RERE

1.57e-04192634e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell15|World / Age, Tissue, Lineage and Cell class

DOC2A CFAP251 TOB1 APP

1.60e-04193634a8ad0de955494d6f5929dc44ba46627d06d95453
ToppCellVE-pDC-|VE / Condition, Cell_class and T cell subcluster

UBE2E2 CD36 PFKFB2 APP

1.60e-04193634583724de588fcde3aeda056138c522dc0225a387
ToppCellControl-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

CD1E TOB1 ENTPD1 PFKFB3

1.60e-041936344cb938c346cc32ec122d11e6b9f25db20e0f7ff6
ToppCellVE-pDC|VE / Condition, Cell_class and T cell subcluster

UBE2E2 CD36 PFKFB2 APP

1.60e-04193634bb759dc9ef0ec41d655002f59021d62d62d44289
ToppCellControl-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

P2RX1 CD36 PFKFB2 APP

1.64e-041946345f95a5a35f73222dbe2ca52cc580f4774f641403
ToppCellControl-Myeloid-MoAM4|Myeloid / Condition, Lineage and Cell class

CD1E ENPP1 CD36 ENTPD1

1.64e-041946347ab808dd1876b0eec2831caa16d04fd859b1dc50
ToppCellIPF-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

CD1E TOB1 ENTPD1 PFKFB3

1.64e-04194634accf4b7b09e2048f2e47a52201e0158684dda8fe
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

FRMD4A SLC11A1 ENTPD1 PIK3R5

1.64e-04194634ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC11A1 P2RX1 PFKFB4 PIK3R5

1.67e-041956341d58585557bf8e9ce4d514e128d3a902b526331d
ToppCellAdult-Immune-monocyte-D231|Adult / Lineage, Cell type, age group and donor

CD1E P2RX1 ENTPD1 PIK3R5

1.67e-04195634ea24da6fea1487acb1e56c28c0649858cc0a12bd
ToppCellChildren_(3_yrs)-Immune-monocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC11A1 ENTPD1 PFKFB3 PIK3R5

1.67e-0419563481a28289eda1a8a1a31b7357106f64ac5000e172
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC11A1 P2RX1 CD36 PIK3R5

1.67e-0419563410ce1b6961f10372d1f65388cbf3626a5fcd6840
ToppCellmyeloid-CD14+_Monocyte|myeloid / Lineage and Cell class

SLC11A1 CD36 ENTPD1 PFKFB3

1.67e-0419563460fab0c24c827567fb42bbd7eb165bf45178c198
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FRMD4A CD36 ENTPD1 PIK3R5

1.67e-04195634247803cf58c6d9c561a52aa34e581188ddad197e
ToppCellControl-Myeloid-MoAM4|Control / Condition, Lineage and Cell class

CD1E ENPP1 CD36 ENTPD1

1.67e-04195634211a736acbe875bd3c1942c62aaacc9b170ece6d
ToppCellControl-Myeloid|Control / Disease state, Lineage and Cell class

FRMD4A SLC11A1 UBE2E2 PIK3R5

1.67e-0419563446ce2e403ca5d757e5ba17349b6c7ce5cde1f195
ToppCellAdult-Immune-monocyte|Adult / Lineage, Cell type, age group and donor

SLC11A1 P2RX1 ENTPD1 PIK3R5

1.70e-041966343ef193c5180de3137daf886492e74fc574bc9767
ToppCellChildren_(3_yrs)-Immune-monocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC11A1 P2RX1 ENTPD1 PIK3R5

1.70e-04196634cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD1E SLC11A1 ENTPD1 PIK3R5

1.70e-04196634291c59b609985167c98a40d4e2caeea2fad74941
ToppCell390C-Myeloid-Dendritic-cDC2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

UBE2E2 ENTPD1 APP ARID5A

1.70e-04196634799f54131fb1034f82ef4872cfb2c64359541086
ToppCellParenchymal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

P2RX1 PFKFB2 PFKFB3 APP

1.70e-04196634b10b386aacc672949560df2dbb0d4f76cf62e213
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SLC11A1 P2RX1 CD36 PIK3R5

1.74e-04197634c6645db1bfb5a352cfbb8d83fd1929dcfd41e216
ToppCellFetal_29-31_weeks-Immune-monocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC11A1 P2RX1 ENTPD1 PIK3R5

1.74e-0419763448a8169a4d33c6a68d66bcd936861c75cb4b60ef
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC11A1 ENTPD1 PFKFB3 PIK3R5

1.74e-04197634e2983ae16c72371fbf0e5c123de9f4d900724e5e
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

SLC11A1 P2RX1 PFKFB4 PIK3R5

1.74e-04197634a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC11A1 CD36 ENTPD1 PIK3R5

1.74e-04197634c9b1f2ee7eb31a66af331c5aae29e1bbb5186f5a
ToppCellFetal_29-31_weeks-Immune-monocyte-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC11A1 P2RX1 ENTPD1 PIK3R5

1.74e-041976348b9a88fb671d5c2b25d291c851e2b8a478f2610c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD1E SLC11A1 ENTPD1 PIK3R5

1.74e-04197634dea1d29154c585ab588e50b83c7c8de7fe24d2d4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC11A1 ENTPD1 PFKFB3 PIK3R5

1.74e-041976341eb9ff8467118b943b5d443cb996168e1e1206b5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD1E SLC11A1 ENTPD1 PIK3R5

1.74e-0419763472cd61b868d57862ec9c230ea68913d3829b0f2b
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRMD4A SLC11A1 ENTPD1 PIK3R5

1.77e-041986346a4161680b46b2c12353a693c403b5a4bb3da03f
ToppCellTracheal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CD36 PFKFB3 PFKFB4 PIK3R5

1.77e-041986340b928a829844f49f4d47e88908af192cb919011f
ToppCellCaecum-(2)_B_cell-(21)_B_cell_IgG_Plasma|Caecum / shred on region, Cell_type, and subtype

LGALSL SCYL1 ERLEC1 CNP

1.77e-041986343893fcfc1de5937be3ccc7e545f711f2c95a2827
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRMD4A SLC11A1 ENTPD1 PIK3R5

1.77e-041986340b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCellCaecum-B_cell-B_cell_IgG_Plasma|Caecum / Region, Cell class and subclass

LGALSL SCYL1 ERLEC1 CNP

1.77e-04198634d8cb78b1763710a158cf22b59aebaa44afd2374c
ToppCellImmune-monocyte|World / Lineage, Cell type, age group and donor

SLC11A1 P2RX1 ENTPD1 PIK3R5

1.77e-04198634d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCellBAL-Severe-Myeloid-cDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CD1E UBE2E2 ENPP1 ENTPD1

1.80e-041996340b20ae65b9340d844e271acda9e116d98fc1cc69
ToppCellControl-Control-Others-RBC|Control / Disease, condition lineage and cell class

CFAP251 UBE2E2 PFKFB2 APP

1.80e-04199634eb4c52d04f572433c0239bf479d0040a309939a1
ToppCellMS-Multiple_Sclerosis-Myeloid-pDC|Multiple_Sclerosis / Disease, condition lineage and cell class

UBE2E2 P2RX1 PFKFB2 APP

1.80e-04199634c10c8c9322cad4996e4aa11a8680e3d781644ace
ToppCellsevere-Myeloid-Neutrophils_4|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SLC11A1 PFKFB2 PFKFB3 ARID5A

1.80e-0419963450242666def13e5d4149c563ae000d6768f086f7
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC11A1 ENTPD1 PFKFB3 PIK3R5

1.80e-04199634951c2ea5af4756832c2adcec3ee70a7e36331a4e
ToppCellBAL-Severe-Myeloid-cDC-cDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CD1E UBE2E2 ENPP1 ENTPD1

1.80e-04199634bb9e7418468b88cdfaa78788d062362794ea8230
ToppCellSepsis-URO-Myeloid-pDC|URO / Disease, condition lineage and cell class

CFAP251 UBE2E2 PFKFB2 APP

1.80e-041996341dc96a1cc313fa175fe50f0df606baa84ea5970b
ToppCellSepsis-ICU-NoSEP-Myeloid-pDC|ICU-NoSEP / Disease, condition lineage and cell class

CFAP251 PFKFB2 APP CNP

1.80e-04199634a199e67438eeed903d0996605591ec54400fdd66
Drugglipentide

PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.73e-097624CID000065779
Drug2-MP

PFKFB1 PFKFB2 PFKFB3 PFKFB4

3.46e-098624CID003015569
Drugfructose 2-phosphorothioate 6-phosphate

PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.62e-0811624CID000195184
Drugcarboxytolbutamide

PFKFB1 PFKFB2 PFKFB3 PFKFB4

4.89e-0814624CID000159651
DrugPK-F

PFKFB1 PFKFB2 PFKFB3 PFKFB4

4.89e-0814624CID000448133
DrugThr-Ala

PFKFB1 PFKFB2 PFKFB3 PFKFB4

6.65e-0815624CID006427021
Drugdibenzyl succinate

PFKFB1 PFKFB2 PFKFB3 PFKFB4

8.85e-0816624CID000007653
DrugN-bromoacetylethanolamine phosphate

PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.16e-0717624CID000188343
DrugAC1L1AO2

PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.48e-0718624CID000001073
Drugbrazilin

PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.48e-0718624CID000073384
Drugmelarsen oxide

PFKFB1 PFKFB2 PFKFB3 PFKFB4

5.08e-0724624CID000030830
Drugmitiglinide

PFKFB1 PFKFB2 PFKFB3 PFKFB4

8.35e-0727624CID000121891
DrugmantATP

PFKFB1 PFKFB2 PFKFB3 PFKFB4

2.45e-0635624CID000123756
DrugLaevuflex

SLC17A1 CD36 PFKFB1 PFKFB2 PFKFB3 PFKFB4 ZFYVE1

9.02e-06272627CID000003426
DrugThioridazine hydrochloride [130-61-0]; Down 200; 9.8uM; HL60; HG-U133A

PES1 PFKFB3 APP PIK3R5 CNP VCP

1.60e-051976261986_DN
DrugAmiloride hydrochloride dihydrate [17440-83-4]; Down 200; 13.2uM; HL60; HG-U133A

TOB1 PFKFB3 APP PIK3R5 CNP VCP

1.64e-051986261970_DN
DrugNefopam hydrochloride [23327-57-3]; Up 200; 13.8uM; PC3; HT_HG-U133A

SLC11A1 ENTPD1 EPB41L5 RERE PIK3R5 ZNF287

1.69e-051996263730_UP
DrugCP-944629 [668990-94-1]; Down 200; 10uM; MCF7; HT_HG-U133A

ENTPD1 EPB41L5 RERE APP EZH1 TOP3A

1.74e-052006267544_DN
Drug3-phosphohistidine

PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.77e-0557624CID000123911
Drug1,6-di-o-phosphonohexopyranose

PFKFB1 PFKFB2 PFKFB3 PFKFB4

2.80e-0564624CID000000737
DrugAC1L19C4

PFKFB1 PFKFB2 PFKFB3 PFKFB4

3.77e-0569624CID000000483
Drugtitanium trichloride

PNN ENPP1

4.36e-054622CID000062646
Drug1 sulfonylurea

ENPP1 PFKFB1 PFKFB2 PFKFB3 PFKFB4

4.42e-05143625CID011819083
Drugfructose-1,6-diphosphate sodium salt

GBE1 PFKFB1 PFKFB2 PFKFB3 PFKFB4

5.73e-05151625CID000000718
Drugallulose 6-phosphate

GBE1 PFKFB1 PFKFB2 PFKFB3 PFKFB4

8.00e-05162625CID000000603
Drugphorbol acetate myristate

P2RX1 PNN ENPP1 CD36 PES1 ICAM4 PFKFB1 PFKFB2 PFKFB3 PFKFB4 APP SLC23A1 TOP3A

8.27e-0513996213CID000004792
Drugsodium azide

SLC17A1 ENPP1 APP SLC23A1

8.56e-0585624CID000033557
Drugtroglitazone

CCNB3 ENPP1 CD36 PFKFB1 PFKFB2 PFKFB3 PFKFB4 PIK3R5

8.70e-05526628CID000005591
Drug2-hexulofuranose

PFKFB1 PFKFB2 PFKFB3 PFKFB4

9.79e-0588624CID000000716
DrugMurnac-tripeptide

PGLYRP4 PNN

1.52e-047622CID000119512
DrugDiflunisal [22494-42-4]; Down 200; 16uM; HL60; HG-U133A

P2RX1 ASH1L PFKFB3 APP PIK3R5

1.69e-041906251990_DN
Drugara-Hx

ENTPD1 PFKFB1 PFKFB2 PFKFB3 PFKFB4

1.82e-04193625CID000000804
DrugDubinidine [22964-77-8]; Up 200; 14.6uM; PC3; HT_HG-U133A

DOC2A SLC11A1 EPB41L5 PFKFB4 EZH1

1.86e-041946255774_UP
DrugPyrantel tartrate [33401-94-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A

FRMD4A CD1E SLC11A1 PFKFB2 RERE

1.91e-041956252260_UP
DrugAlfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; PC3; HT_HG-U133A

SLC11A1 ENTPD1 ICAM4 EZH1 ZNF287

1.95e-041966254644_UP
DrugCephalexin monohydrate [23325-78-2]; Down 200; 11uM; MCF7; HT_HG-U133A

ASH1L EPB41L5 HMGXB3 APP SOWAHC

1.95e-041966252628_DN
DrugAdrenosterone [382-45-6]; Up 200; 13.4uM; PC3; HT_HG-U133A

FRMD4A SLC11A1 PFKFB2 PIK3R5 TOP3A

2.00e-041976255045_UP
Drugdiiodomethane

ICAM4 APP

2.02e-048622CID000006346
DrugOrange I

PNN APP

2.02e-048622CID005359467
Drugretinoic acid; Down 200; 1uM; PC3; HT_HG-U133A

ENTPD1 RERE PFKFB4 TOP3A ZNF287

2.05e-041986254435_DN
Drug5255229; Down 200; 13uM; MCF7; HT_HG-U133A_EA

ASH1L HMGXB3 APP EZH1 TOP3A

2.05e-04198625949_DN
Drugtolbutamide

ENPP1 PFKFB1 PFKFB2 PFKFB3 PFKFB4

2.05e-04198625CID000005505
DrugFurosemide [54-31-9]; Down 200; 12uM; HL60; HG-U133A

SLC11A1 P2RX1 ASH1L HMGXB3 EZH1

2.10e-041996251580_DN
DrugTrimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A

DOC2A ENTPD1 EPB41L5 HMGXB3 RERE

2.10e-041996251502_DN
DrugAltretamine [654-05-6]; Up 200; 19uM; MCF7; HT_HG-U133A

MASP1 CD1E PGLYRP4 ENPP1 PFKFB2

2.10e-041996255688_UP
DrugOxolinic acid [14698-29-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A

SLC11A1 P2RX1 PFKFB2 RERE ZNF287

2.10e-041996252266_UP
DrugDecamethonium bromide [541-22-0]; Up 200; 9.6uM; PC3; HT_HG-U133A

PGLYRP4 SLC11A1 P2RX1 ENTPD1 APP

2.14e-042006254094_UP
Druggenistein; Up 200; 10uM; PC3; HT_HG-U133A

CD1E PFKFB2 RERE PIK3R5 ZNF287

2.14e-042006251235_UP
Disease4-hydroxyphenylpyruvate measurement

CFAP251 SLC17A1

2.43e-054602EFO_0800120
Diseasepulmonary tuberculosis (is_implicated_in)

SLC11A1 CD36 GBE1

8.67e-0542603DOID:2957 (is_implicated_in)
DiseaseBrain hemorrhage

APP SLC23A1

1.81e-0410602C0553692
Diseasedecadienedioic acid (C10:2-DC) measurement

SLC17A1 ZFYVE1

1.81e-0410602EFO_0800598

Protein segments in the cluster

PeptideGeneStartEntry
AAHVLRKPIFGRYKP

FAM234A

366

Q9H0X4
KCPLHTVLKLTPVAY

PFKFB1

416

P16118
PLHTIFKLTPVAYGC

PFKFB2

416

O60825
VVILTPLLCSHPKYR

ERLEC1

236

Q96DZ1
KGCFYTHPTEVLKPV

ARID5A

341

Q03989
YVCRPAIKTTIKHPR

ASH1L

106

Q9NR48
KTHPHFVIPYRCLVG

APP

106

P05067
TTILGICRPIKPIYK

BVES-AS1

11

Q5T3Y7
SLPGHPDCKTIRIIY

DTX4

491

Q9Y2E6
DLPIKIYGRIIPCKH

CBLL2

61

Q8N7E2
NYRHKPLKLECPVAG

DANCR

136

P0C864
TIYGKICHFRKPPVL

CCNB3

291

Q8WWL7
LGFPYIKPCKLVHLQ

CFAP251

486

Q8TBY9
MLGSKPRVHLYILPC

OR9K2

1

Q8NGE7
VYFPRLIVPFCGHIK

LGALSL

31

Q3ZCW2
IGRPLHYPVLVTKAC

OR52W1

131

Q6IF63
CPLSKGFQYIRVHVP

MCMDC2

156

Q4G0Z9
FRAHIPPLGLKVYKI

MAN2A1

706

Q16706
PPRHFTGGKIYKVCP

HMGXB3

1051

Q12766
KTKPHLFYIPGRMCP

PNN

236

Q9H307
CPRMTLPAKYGIIIH

PGLYRP4

226

Q96LB8
VKHPPSVKYARCFLS

EEF2KMT

61

Q96G04
KCPLHTVLKLTPVAY

PFKFB3

411

Q16875
PLHTVLKLTPVAYGC

PFKFB4

416

Q16877
FRCSYVPTKPIKHTI

FLNC

726

Q14315
LGEVCHLYYPKVPRT

SLC11A1

121

P49279
FRIPLSPVHKCSFYK

ENPP1

716

P22413
EILRDPCFHPGYKKV

ENTPD1

276

P49961
FPKKSGPVVLYFCVR

FRMD4A

86

Q9P2Q2
LQLVCHVSGFYPKPV

CD1E

226

P15812
KQVKIGSPYCLHLRV

EPB41L5

106

Q9HCM4
YKHFTCNVLPRIKGL

GBE1

216

Q04446
DPYVKLHLLPGACKA

DOC2A

126

Q14183
SKCKEGRPVYISLPH

CD36

331

P16671
YFGKRPPGVLHCTTK

CNP

241

P09543
YIKIKVGPKVLGPFC

MASP1

246

P48740
PPVLKGRKYTLRCHV

ICAM4

141

Q14773
ICKPLHYKRILTPQV

OR52I2

156

Q8NH67
KRLPYCKGNVIPHTY

OR52N1

166

Q8NH53
ACIIGYLEIHPAKKP

MTA3

531

Q9BTC8
KTLHPLCPVFQLGYV

P2RX1

221

P51575
FCSGLAPHFPIKKVL

STRIP2

256

Q9ULQ0
KIPKTLVPHYCELVG

SCYL1

231

Q96KG9
GTIRVPAPCKYAHKL

PIWIL2

936

Q8TC59
RLPPKKVPGFCSFRY

SLC17A1

6

Q14916
YVHLKKRFCEGPSEP

SOWAHC

76

Q53LP3
VKIHPSYCGPAILRF

RD3

86

Q7Z3Z2
DCRIHFKKYGELPPI

RERE

531

Q9P2R6
PIRGRPKKCLVYPHA

SPATA4

31

Q8NEY3
IVHRKILPGEKPYKC

ZNF287

356

Q9HBT7
FKPPKVTFRTRIYHC

UBE2E2

116

Q96LR5
RLCILKGIYPHEPKH

PES1

36

O00541
GKLHTIPIPVARCYT

PIK3R5

276

Q8WYR1
ITFLKYIPICPVFKG

SLC23A1

556

Q9UHI7
SIQPCPDVKYGKRIH

VCP

101

P55072
VFVQCRHPPALRGKY

TRIL

386

Q7L0X0
GHPFLKKCTIESIFP

EZH1

76

Q92800
GIIKLVIHFRMYCPP

nan

46

Q8N8P6
PVCQPHPVYRLKLKF

TOP3A

706

Q13472
PEKPYKGSGFRCIHI

TOB1

46

P50616
IRLKPGHVPYCDLCK

ZFYVE1

61

Q9HBF4
CLLGPTLKKRYPTVH

TPRN

536

Q4KMQ1
VHKKRKCPGPIITYH

VPS72

201

Q15906
IPIRPCVLKYLGKTH

TRRAP

2686

Q9Y4A5
CKVHIRVYLPPLDSG

WWC3

636

Q9ULE0