Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3K4 monomethyltransferase activity

SETD1A SETD1B

2.14e-058182GO:0140945
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

SETD1A SETD1B

3.44e-0510182GO:0140999
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

SETD1A SETD1B

1.44e-0420182GO:0042800
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

FOXA1 SOX2 NCOA2 SETD1A

4.55e-04417184GO:0061629
GeneOntologyMolecularFunctionS-adenosylmethionine-dependent methyltransferase activity

SETD1A TRMT10C SETD1B

4.66e-04172183GO:0008757
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

SETD1A SETD1B

7.10e-0444182GO:0140938
GeneOntologyMolecularFunctionmethyltransferase activity

SETD1A TRMT10C SETD1B

8.68e-04213183GO:0008168
GeneOntologyMolecularFunctiontransferase activity, transferring one-carbon groups

SETD1A TRMT10C SETD1B

1.00e-03224183GO:0016741
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

FOXA1 SOX2 NCOA2 SETD1A

1.58e-03582184GO:0140297
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

SETD1A SETD1B

1.69e-0368182GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

SETD1A SETD1B

1.74e-0369182GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

SETD1A SETD1B

1.84e-0371182GO:0042054
GeneOntologyMolecularFunctionprotein methyltransferase activity

SETD1A SETD1B

3.82e-03103182GO:0008276
GeneOntologyMolecularFunctionN-methyltransferase activity

SETD1A SETD1B

3.97e-03105182GO:0008170
GeneOntologyMolecularFunctiontranscription factor binding

FOXA1 SOX2 NCOA2 SETD1A

4.02e-03753184GO:0008134
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

FOXA1 SOX2 NCOA2 TARDBP KLF18

4.03e-031244185GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

FOXA1 SOX2 NCOA2 TARDBP KLF18

4.42e-031271185GO:0000987
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

FOXA1 SOX2 NCOA2 TARDBP KLF18

7.93e-031459185GO:0000977
GeneOntologyMolecularFunctionserine-type endopeptidase activity

TPP2 C2

1.25e-02190182GO:0004252
GeneOntologyCellularComponentnuclear body

SOX2 NCOA2 TPP2 TARDBP SETD1A SETD1B

7.59e-05903186GO:0016604
GeneOntologyCellularComponentSet1C/COMPASS complex

SETD1A SETD1B

8.34e-0516182GO:0048188
GeneOntologyCellularComponentmethyltransferase complex

SETD1A TRMT10C SETD1B

1.03e-04108183GO:0034708
GeneOntologyCellularComponentnuclear speck

SOX2 TARDBP SETD1A SETD1B

4.34e-04431184GO:0016607
GeneOntologyCellularComponenthistone methyltransferase complex

SETD1A SETD1B

1.87e-0375182GO:0035097
DomainN-SET

SETD1A SETD1B

7.80e-072172PF11764
DomainCOMPASS_Set1_N-SET

SETD1A SETD1B

7.80e-072172IPR024657
DomainN-SET

SETD1A SETD1B

7.80e-072172SM01291
DomainPostSET

SETD1A SETD1B

9.29e-0516172SM00508
DomainPost-SET_dom

SETD1A SETD1B

9.29e-0516172IPR003616
DomainPOST_SET

SETD1A SETD1B

9.29e-0516172PS50868
DomainSET

SETD1A SETD1B

6.26e-0441172PF00856
DomainSET

SETD1A SETD1B

7.88e-0446172SM00317
DomainRRM_1

TARDBP SETD1A SETD1B

8.25e-04208173PF00076
DomainSET_dom

SETD1A SETD1B

9.31e-0450172IPR001214
DomainSET

SETD1A SETD1B

9.31e-0450172PS50280
DomainRRM

TARDBP SETD1A SETD1B

9.33e-04217173SM00360
DomainRRM_dom

TARDBP SETD1A SETD1B

1.06e-03227173IPR000504
DomainRRM

TARDBP SETD1A SETD1B

1.10e-03230173PS50102
Domain-

TARDBP SETD1A SETD1B

1.31e-032441733.30.70.330
DomainNucleotide-bd_a/b_plait

TARDBP SETD1A SETD1B

1.54e-03258173IPR012677
PathwayREACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES

SETD1A SETD1B

7.27e-0438152MM17073
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

NCOA2 SETD1A SETD1B

7.67e-04175153MM14941
PathwayREACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP

NCOA2 LSS

8.88e-0442152M27172
PathwayREACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES

SETD1A SETD1B

8.88e-0442152M48018
PathwayKEGG_LYSINE_DEGRADATION

SETD1A SETD1B

9.74e-0444152M13720
PathwayREACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

SETD1A SETD1B

9.74e-0444152MM15527
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

SETD1A SETD1B

1.06e-0346152MM14933
PathwayREACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF

NCOA2 LSS

1.52e-0355152M27001
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

FOXA1 NCOA2

1.99e-0363152MM15613
PathwayWP_HISTONE_MODIFICATIONS

SETD1A SETD1B

2.11e-0365152M39374
Pubmed

In Vivo and In Vitro Characterization of the RNA Binding Capacity of SETD1A (KMT2F).

SETD1A SETD1B

2.83e-07219238003223
Pubmed

Cell-specific expression of ENACα gene by FOXA1 in the glucocorticoid receptor pathway.

FOXA1 SCNN1A

2.83e-07219232838581
Pubmed

The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation.

SETD1A SETD1B

2.83e-07219224550110
Pubmed

ENaC inhibition stimulates HCl secretion in the mouse cortical collecting duct. I. Stilbene-sensitive Cl- secretion.

CLCN5 SCNN1A

2.83e-07219225925258
Pubmed

The transcriptional regulation of SOX2 on FOXA1 gene and its application in diagnosis of human breast and lung cancers.

FOXA1 SOX2

2.83e-07219225016694
Pubmed

WDR82, a key epigenetics-related factor, plays a crucial role in normal early embryonic development in mice.

SETD1A SETD1B

8.48e-07319221123813
Pubmed

Molecular insight into the SETD1A/B N-terminal region and its interaction with WDR82.

SETD1A SETD1B

8.48e-07319237030068
Pubmed

The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers.

SETD1A SETD1B

8.48e-07319233567280
Pubmed

Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.

SETD1A SETD1B

2.82e-06519225561738
Pubmed

New nomenclature for chromatin-modifying enzymes.

NCOA2 SETD1A SETD1B

3.97e-065719318022353
Pubmed

H3K4 Methyltransferase Set1a Is A Key Oct4 Coactivator Essential for Generation of Oct4 Positive Inner Cell Mass.

SOX2 SETD1A

4.24e-06619226785054
Pubmed

CXXC finger protein 1 contains redundant functional domains that support embryonic stem cell cytosine methylation, histone methylation, and differentiation.

SETD1A SETD1B

5.93e-06719219433449
Pubmed

Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.

SETD1A SETD1B

7.90e-06819223130995
Pubmed

CFP1 interacts with DNMT1 independently of association with the Setd1 Histone H3K4 methyltransferase complexes.

SETD1A SETD1B

7.90e-06819218680430
Pubmed

The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.

SETD1A SETD1B

7.90e-06819222266653
Pubmed

Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex.

SETD1A SETD1B

7.90e-06819217355966
Pubmed

Epigenetic maintenance of adult neural stem cell quiescence in the mouse hippocampus via Setd1a.

SOX2 SETD1A

1.02e-05919238971831
Pubmed

Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.

SETD1A SETD1B

1.02e-05919222665483
Pubmed

Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors.

SOX2 SETD1A

1.02e-05919226691508
Pubmed

Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes.

SETD1A SETD1B

1.27e-051019217998332
Pubmed

Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS.

SETD1A SETD1B

1.27e-051019218838538
Pubmed

Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function.

FOXA1 SOX2

1.55e-051119234009125
Pubmed

beta-Catenin promotes respiratory progenitor identity in mouse foregut.

FOXA1 SOX2

1.86e-051219219805295
Pubmed

Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.

SETD1A SETD1B

1.86e-051219227563068
Pubmed

The amn gene product is required in extraembryonic tissues for the generation of middle primitive streak derivatives.

FOXA1 SOX2

2.56e-05141929851841
Pubmed

Tbx6-dependent Sox2 regulation determines neural or mesodermal fate in axial stem cells.

FOXA1 SOX2

2.96e-051519221331042
Pubmed

SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53.

SETD1A SETD1B

3.38e-051619223870121
Pubmed

Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival.

FOXA1 SOX2

3.38e-051619218332127
Pubmed

Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(-/-)/Tcf1(-/-) embryos.

FOXA1 SOX2

3.38e-051619215057272
Pubmed

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.

SETD1A SETD1B

3.38e-051619224368734
Pubmed

Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.

FOXA1 NCOA2

3.83e-051719219183483
Pubmed

Identification of novel human WW domain-containing proteins by cloning of ligand targets.

CLCN5 SCNN1A

4.30e-05181929169421
Pubmed

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis.

FOXA1 SOX2

4.81e-051919223006325
Pubmed

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.

SETD1A SETD1B

5.34e-052019229785026
Pubmed

Structural basis for activity regulation of MLL family methyltransferases.

SETD1A SETD1B

6.49e-052219226886794
Pubmed

Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells.

FOXA1 NCOA2

7.10e-052319219737349
Pubmed

Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium.

FOXA1 SOX2

7.75e-052419221803035
Pubmed

Compartment-dependent activities of Wnt3a/β-catenin signaling during vertebrate axial extension.

FOXA1 SOX2

9.84e-052719225152336
Pubmed

Molecular Characterization of the Genital Organizer: Gene Expression Profile of the Mouse Urethral Plate Epithelium.

FOXA1 SOX2

9.84e-052719227173853
Pubmed

The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion.

SCNN1A LSS

1.06e-042819229212953
Pubmed

Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors.

FOXA1 SOX2

1.22e-043019232453714
Pubmed

Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells.

FOXA1 SOX2

1.22e-043019225804738
Pubmed

Identification and characterization of a novel human PP1 phosphatase complex.

SETD1A SETD1B

1.30e-043119220516061
Pubmed

Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells.

SOX2 LSS

1.30e-043119219796621
Pubmed

Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation.

FOXA1 SOX2

1.30e-043119236476860
Pubmed

Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium.

FOXA1 SOX2

1.86e-043719223266329
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

FOXA1 NCOA2 TARDBP

2.24e-0422019335785414
Pubmed

Gpr177 regulates pulmonary vasculature development.

FOXA1 SOX2

2.64e-044419223884445
Pubmed

Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition.

FOXA1 SOX2

3.01e-044719217198697
Pubmed

The emergent landscape of the mouse gut endoderm at single-cell resolution.

FOXA1 SOX2

3.14e-044819230959515
Pubmed

Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.

SCNN1A NCOA2 LSS

3.27e-0425019318660489
Pubmed

Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.

SETD1A SETD1B

3.41e-045019237974198
Pubmed

Global expression analysis of gene regulatory pathways during endocrine pancreatic development.

FOXA1 SOX2

4.13e-045519214660441
Pubmed

A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.

SETD1A SETD1B

5.08e-046119220305087
InteractionNCOA6 interactions

FOXA1 SOX2 NCOA2 SETD1A SETD1B

1.04e-07145175int:NCOA6
InteractionKMT2C interactions

FOXA1 SOX2 SETD1A SETD1B

4.16e-06134174int:KMT2C
InteractionBAG2 interactions

FOXA1 SOX2 NCOA2 TARDBP SETD1A LSS

7.81e-06622176int:BAG2
InteractionKDM6A interactions

FOXA1 SOX2 SETD1A SETD1B

8.83e-06162174int:KDM6A
InteractionPAXIP1 interactions

FOXA1 SOX2 TARDBP SETD1A SETD1B

9.05e-06359175int:PAXIP1
InteractionWDR82 interactions

FOXA1 SOX2 SETD1A SETD1B

2.59e-05213174int:WDR82
InteractionPHF20L1 interactions

SOX2 SETD1A SETD1B

3.24e-0575173int:PHF20L1
InteractionRFC4 interactions

FOXA1 SOX2 TARDBP NEURL4

3.33e-05227174int:RFC4
InteractionFAM98A interactions

FOXA1 SOX2 TARDBP NEURL4

3.93e-05237174int:FAM98A
InteractionASH2L interactions

FOXA1 SOX2 SETD1A SETD1B

6.08e-05265174int:ASH2L
InteractionZNF608 interactions

SOX2 SETD1A SETD1B

6.17e-0593173int:ZNF608
InteractionAREG interactions

FOXA1 NEURL4

7.98e-0516172int:AREG
InteractionSUMO1 interactions

FOXA1 SOX2 NCOA2 LSS

8.28e-05287174int:SUMO1
InteractionDLX1 interactions

FOXA1 SOX2

1.02e-0418172int:DLX1
InteractionLDB1 interactions

FOXA1 SOX2 TARDBP

1.16e-04115173int:LDB1
InteractionLBP interactions

SOX2 SETD1A

1.39e-0421172int:LBP
InteractionSH3BGRL2 interactions

FOXA1 SOX2

1.53e-0422172int:SH3BGRL2
InteractionCD58 interactions

FOXA1 SOX2

1.83e-0424172int:CD58
InteractionBOD1L1 interactions

SOX2 SETD1A SETD1B

2.50e-04149173int:BOD1L1
InteractionDLX5 interactions

FOXA1 NCOA2

2.68e-0429172int:DLX5
InteractionANAPC7 interactions

SOX2 SETD1A TRMT10C

3.19e-04162173int:ANAPC7
InteractionMSI2 interactions

FOXA1 SOX2 TARDBP

3.55e-04168173int:MSI2
InteractionKMT2D interactions

SOX2 SETD1A SETD1B

3.61e-04169173int:KMT2D
InteractionGALC interactions

SOX2 NEURL4

3.70e-0434172int:GALC
InteractionCEP290 interactions

FOXA1 TARDBP NEURL4

4.28e-04179173int:CEP290
InteractionATN1 interactions

FOXA1 SETD1A SETD1B

4.86e-04187173int:ATN1
InteractionNFIA interactions

FOXA1 SOX2 NCOA2

4.93e-04188173int:NFIA
InteractionDIMT1 interactions

FOXA1 SOX2 TARDBP

5.01e-04189173int:DIMT1
InteractionC5 interactions

SOX2 C2

5.13e-0440172int:C5
InteractionNOP16 interactions

FOXA1 SOX2 TARDBP

5.17e-04191173int:NOP16
InteractionSDAD1 interactions

FOXA1 SOX2 TARDBP

5.33e-04193173int:SDAD1
InteractionNR5A2 interactions

FOXA1 NCOA2

5.39e-0441172int:NR5A2
InteractionCNP interactions

FOXA1 SOX2 TARDBP

6.17e-04203173int:CNP
InteractionDPY30 interactions

FOXA1 SETD1A SETD1B

6.26e-04204173int:DPY30
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETD1A SETD1B

3.55e-0434152487
GeneFamilyRNA binding motif containing

TARDBP SETD1A SETD1B

6.61e-04213153725
CoexpressionGSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP

NCOA2 TPP2 TARDBP SETD1B

1.17e-05200194M9889
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#3_top-relative-expression-ranked_100

FOXA1 SOX2

1.89e-058182DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k3_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_100

FOXA1 SOX2

6.14e-0514182DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#4_top-relative-expression-ranked_200

FOXA1 SOX2

1.03e-0418182DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k4_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_100

FOXA1 SOX2

1.70e-0423182gudmap_developingLowerUrinaryTract_e14.5_ urethra_100_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_200

FOXA1 SOX2

1.85e-0424182gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#1_top-relative-expression-ranked_500

FOXA1 SOX2

2.53e-0428182DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k1_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_200

FOXA1 SOX2

3.53e-0433182DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#5_top-relative-expression-ranked_500

FOXA1 SOX2

3.53e-0433182gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_k-means-cluster#4_top-relative-expression-ranked_100

FOXA1 SOX2

3.53e-0433182gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_100_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#4_top-relative-expression-ranked_200

FOXA1 SOX2

4.94e-0439182gudmap_developingLowerUrinaryTract_e14.5_ urethra_200_k4
ToppCellsevere-unassigned|World / disease stage, cell group and cell class

CLCN5 NCOA2 NEURL4

4.41e-05164193b3a45c150df6594debeeca400cc58d30ef662756
ToppCellsevere-unassigned|severe / disease stage, cell group and cell class

CLCN5 NCOA2 NEURL4

4.49e-05165193f9ddd547992fec065d539a1d0305acba8fc7d79c
ToppCellfacs-Trachea-nan-24m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXA1 SCNN1A SOX2

5.00e-05171193d2a10e94b0490120d1420b944302eb841f902c64
ToppCell367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|367C / Donor, Lineage, Cell class and subclass (all cells)

FOXA1 SCNN1A SOX2

5.17e-05173193d8e965ff7e9b758876ec1521c1ccedd739e8d673
ToppCell367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|367C / Donor, Lineage, Cell class and subclass (all cells)

FOXA1 SCNN1A SOX2

5.17e-05173193c2d973356c40e0284fd3bd7733a164b141c66008
ToppCellfacs-Trachea-nan-18m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXA1 SCNN1A SOX2

5.35e-05175193eb87275da6f61ecb4fbc89421dfd27bead1e0f48
ToppCellfacs-Trachea-nan-18m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXA1 SCNN1A SOX2

5.35e-051751933883675a726dd0c6c3a7113d59be2a093ea2dc6f
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FOXA1 SCNN1A SOX2

6.02e-05182193dc29e8735c3562ce32322351d28f7d9709208ebf
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOXA1 SCNN1A SOX2

6.11e-05183193514b72a1ae55656934839800513385e19bc240e2
ToppCellPND07-28-samps-Epithelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

FOXA1 SCNN1A SOX2

6.11e-05183193a98f1d71d82ed6cca996f74352ab834fb6e95206
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

6.21e-0518419345ff845ceed5960a997545c1009012b65e377d50
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOXA1 SCNN1A SOX2

6.21e-0518419349eccf72725593a8fb4a529e7985a5c413b3ca6a
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOXA1 SCNN1A SOX2

6.21e-0518419341164109d9d7bb1c431220e2e85e08dc5f56856d
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

6.21e-051841932cc2646dee3c6001f7c10b7449c17d1935021958
ToppCellfacs-Trachea-nan-24m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXA1 SCNN1A SOX2

6.42e-051861936c06163d7315f1c71b15fe76f2e696bf3fa73b67
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

6.42e-0518619337b93ebd64ebbd08193a746e5bc9b350c2570733
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FOXA1 SCNN1A SOX2

6.42e-05186193dfd67d67c103c942de6c8acef8d81e57a9886154
ToppCellfacs-Trachea-nan-24m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXA1 SCNN1A SOX2

6.42e-0518619378e3b00eb347d1aa197671e31be9b0c6e4235760
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

6.52e-05187193796046ff066a9c3847faa9bf1f8beccd956c01f7
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

6.52e-05187193380c3e0bc73b266718893a3b3ca207ce5fd31883
ToppCellfacs-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXA1 SCNN1A SOX2

6.52e-05187193fe9fc21192ede2eea61f419d20ccda254569d0a6
ToppCelldroplet-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXA1 SCNN1A SOX2

6.52e-051871935b3c3c6421efd25c740ae121968b5520bbdc07b2
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

6.62e-05188193137ed9958044fab7a13648affb469585d1c48cf6
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FOXA1 SCNN1A SOX2

6.62e-051881933cfba3addcc9058f4ec31ad96261f79988f551a0
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

6.62e-051881938ffb5394f7b00ea483a5fe4df894d22fda935e5c
ToppCellfacs-Trachea-3m-Epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

6.73e-05189193f8959cc2c14899c8dfeb1b5e51e187537df2f03e
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

6.73e-05189193ee15b4fb3a1cfda80bcf210a23f04f242594015e
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

6.73e-05189193dc6f6fae84347d145bea71b49eaeeb3028e9c4ae
ToppCelldroplet-Trachea-nan-3m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXA1 SCNN1A SOX2

6.83e-05190193434de72dde09644efbddcaa643a4a3eaf5f643bf
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

6.83e-0519019301e7747547ea1f3049a11a1717565ba71dd52bdc
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

6.83e-05190193576c45a30a4808b47433bc6c2c41396135556c40
ToppCelldroplet-Trachea-nan-3m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXA1 SCNN1A SOX2

6.83e-05190193e647f9a2dcf7f2dffef53c45bbe171416518fd59
ToppCelldroplet-Trachea-3m-Epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

6.83e-051901930114cf48612d78c3ada4d8a05850501fef6892c5
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

6.94e-05191193cd4e2e883c4955fb2d875e41bb6ebc680994dc8c
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-leukocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXA1 SCNN1A SOX2

6.94e-05191193116fba9badea093e11f370996247cca0e4c02e8f
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FOXA1 SCNN1A SOX2

6.94e-0519119363aa671837b79d2feb7ed1e67712cc01caf72bef
ToppCell367C-Epithelial_cells|367C / Donor, Lineage, Cell class and subclass (all cells)

FOXA1 SCNN1A SOX2

6.94e-05191193d31975fc33779b0b3ff1a50d7c64fec8d08be4d4
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FOXA1 SCNN1A SOX2

6.94e-0519119305731ece7867659c662f952812805f947032fe10
ToppCell18-Distal-Epithelial-Secretory_progenitor|Distal / Age, Tissue, Lineage and Cell class

FOXA1 SOX2 C2

7.05e-051921939fae988ecd2ef1231bfd42a678a4903517694cbe
ToppCellfacs-Trachea-18m-Epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

7.05e-05192193c5823c5d4c58a4e9121a4b7d7256481d6d9e9b7f
ToppCellfacs-Lung-EPCAM-18m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXA1 SCNN1A SOX2

7.05e-0519219312096302a3a4d26e21ca04357aa557143f482155
ToppCellCOVID-19-lung-Secretory|COVID-19 / Disease (COVID-19 only), tissue and cell type

FOXA1 SCNN1A SOX2

7.05e-0519219359261098ccb52306f837f632ebaea45b90ad30fe
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FOXA1 SCNN1A SOX2

7.05e-05192193b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FOXA1 SCNN1A SOX2

7.16e-05193193aa10924b203c71e65fdbd2b90ba131dbd362d8b1
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FOXA1 SCNN1A SOX2

7.16e-051931938603d1a38955ad2529d04e4704467c73ea5bfbda
ToppCellfacs-Lung-18m-Epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

7.16e-051931938e934f127bc763e905c788beabfa867bd559b682
ToppCellfacs-Trachea-24m-Epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXA1 SCNN1A SOX2

7.16e-05193193ec49a83b24371579d4ad46aad91c25115aa226f9
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FOXA1 SCNN1A SOX2

7.27e-05194193b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCellfacs-Trachea-nan-3m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXA1 SCNN1A SOX2

7.27e-051941933701ca87c6dc9ccd7b4146e56371546174d26c36
ToppCellfacs-Trachea-nan-3m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXA1 SCNN1A SOX2

7.27e-0519419365f9bf126be26114c2c3f4c46d48318986212a92
ToppCellNS-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 SCNN1A SOX2

7.38e-05195193b0d782eeee30c797b4da9b3be29b864983fd9e71
ToppCellAT2_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

SCNN1A C2 LSS

7.38e-05195193b0cea3f4e59635913d243612f2e8cf4c7b34e726
ToppCellNS-moderate-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 SCNN1A SOX2

7.49e-0519619347930de6b47b7bf22d8dae8b7419a9cd1d22f0ea
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Club|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FOXA1 SCNN1A SOX2

7.49e-051961934e4c632db73b1340d80bf40a7657cb4821084d3c
ToppCellcritical-Epithelial-Secretory|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FOXA1 SCNN1A SOX2

7.49e-051961937da687eb983a54c28ee990424cc52e01caf5f4aa
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXA1 SCNN1A SOX2

7.61e-05197193ec08a971e8dd9ad69359896c60ad77ff8af08fd0
ToppCellBL-critical-LOC-Epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 SCNN1A SOX2

7.72e-051981936218a25b94d5fa2c69880539adf9c63bfe52dcd3
ToppCellmoderate-Epithelial-Secretory|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FOXA1 SCNN1A SOX2

7.72e-051981937d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Club|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FOXA1 SCNN1A SOX2

7.72e-051981935d57acbe0d245f8bd217eeea07af060092898fbd
ToppCellBL-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 SCNN1A SOX2

7.72e-05198193484d16aaa601a1e11b871b0475dd01a2de1a29ce
ToppCellcritical-Epithelial-FOXN4+|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FOXA1 SOX2 TPP2

7.72e-051981936b160b3d6a2c1b1641c2c7dcec1a7ef38411fec9
ToppCelldistal-Epithelial-Club-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOXA1 SCNN1A SOX2

7.72e-05198193e56a5ffadfa4d1e34d34aec43eaf560cd80286e1
ToppCellNS-critical-d_07-13|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 SCNN1A SOX2

7.72e-05198193a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FOXA1 SCNN1A SOX2

7.84e-05199193a8bfc0b93ad9968cf52a25be86995ffe436bd636
ToppCellcellseq2-Epithelial|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FOXA1 SCNN1A SOX2

7.84e-051991932d4fb558845764f937efaf39962caaeb2c85478b
ToppCellcellseq2-Epithelial-Epithelial_Glandular|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FOXA1 SCNN1A SOX2

7.84e-05199193ca78fd6e310232b25b864ed02ff9242fe1aa8206
ToppCellNS-critical-d_07-13-Epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 SCNN1A SOX2

7.84e-05199193b88a81cd2a89f4d27100c96ae4324dcee68daf83
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Transitional_AT2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FOXA1 SCNN1A SOX2

7.84e-05199193b44d74895846e2ac144438b73e0ca91e3949c16c
ToppCellNS-critical-LOC-Epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 SCNN1A SOX2

7.84e-05199193d64adb68502be596ce55fb2cb63fe1cfa2c5f8ba
ToppCellNS-moderate-d_16-33-Epithelial|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 SCNN1A SOX2

7.84e-05199193aa2b51940115c22768c0d7493b4b60d41df3f376
ToppCellcritical-Epithelial|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FOXA1 SCNN1A SOX2

7.84e-05199193bbb44e2a52f102a6d891ead6c06d6c07221abd33
ToppCellNS-critical-d_16-33-Epithelial|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 SCNN1A SOX2

7.84e-051991933b68197ec01c5f2b315d9e9b6eb02d5f6b5b77a3
ToppCellBronchial_Biopsy-Epithelial|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

FOXA1 SCNN1A SOX2

7.84e-05199193ef5d8917c8d011184830a0b8197afc6266707b37
ToppCelldistal-Epithelial-Mucous|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOXA1 SCNN1A SOX2

7.84e-05199193a7fe7b792d696f369ad0310a772160a1729ef223
ToppCelldistal-Epithelial-Club|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOXA1 SCNN1A SOX2

7.84e-05199193c63ccce1285352927fd8c4f7374ec5fff8d70cec
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Transitional_AT2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

FOXA1 SCNN1A SOX2

7.84e-051991939e8231c9007d8d963805a4c99e0905538ceb9b60
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Basal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FOXA1 SOX2 SATL1

7.84e-05199193e9c47f565a0a7737ecff68569d668aeb707ae5a6
ToppCelldistal-3-Epithelial-Club|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOXA1 SCNN1A SOX2

7.84e-051991931a0c3506df2438f5be40a8ea72effe5f8ebd35c4
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Transitional_AT2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FOXA1 SCNN1A SOX2

7.84e-051991934b374a5de82b4614d3d8a00202ea6cb8f1fd8104
ToppCellBAL-Severe-Epithelial|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FOXA1 SCNN1A SOX2

7.96e-05200193b762bf6f432eac05a476f6e2ab4da27dd13a2317
ToppCellTracheal-10x3prime_v2-Epithelial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FOXA1 SCNN1A SOX2

7.96e-05200193e1da1b15d2ca06796ee1ab7cef586ae0b4dc0a0a
ToppCellcellseq-Epithelial|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FOXA1 SCNN1A SOX2

7.96e-05200193e4204c4b864346f47d76b0f0faae96f04fed5082
ToppCellmedial-Epithelial|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOXA1 SCNN1A SOX2

7.96e-0520019317bb9a9016058cbb70c7bd894c12f6208ff07895
ToppCellBAL-Severe-Epithelial-Epithelial|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

FOXA1 SCNN1A SOX2

7.96e-052001934c63204e0d868dd4c11c1604a238624a3ad54485
ToppCellTracheal-10x5prime-Epithelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FOXA1 SCNN1A SOX2

7.96e-05200193efd461c687155c84ef590352207e6fe4ba392a90
ToppCellcontrol-Epithelial|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FOXA1 SCNN1A SOX2

7.96e-05200193f95bbb94e51ac28b1995026c599ec3a34e012916
ToppCelldistal-2-Epithelial|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOXA1 SCNN1A SOX2

7.96e-052001932fc1e95706f212bf18ecdf6eb5b3182ac98c9b52
ToppCellBronchial-10x5prime-Epithelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FOXA1 SCNN1A SOX2

7.96e-05200193d3ee5f79513e2ac02ad3329b59e6290d457c44d2
ToppCellParenchyma_COVID-19-Epithelial-TX-Club|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

FOXA1 SCNN1A SOX2

7.96e-0520019385f946dd3831acf3488c87efba96689cc2667c3a
ToppCellmoderate-Epithelial|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FOXA1 SCNN1A SOX2

7.96e-05200193095783c9b75113ae350c2d5fb1195d71b41fa695
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 SCNN1A SOX2

7.96e-05200193ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellParenchyma_COVID-19-Epithelial-TX|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

FOXA1 SCNN1A SOX2

7.96e-05200193d5426cd318a8f90c0bd8f9804351ab230fafc995
ToppCellNS-moderate-d_07-13-Epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FOXA1 SCNN1A SOX2

7.96e-0520019385940b4bf7971b872469dea8b8d7a45bdeb2a909
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FOXA1 SCNN1A SOX2

7.96e-0520019305262530ce87cfdd6bcbce5ae03cf4e3f9a74a02
ToppCellBAL-Severe-Epithelial-Epithelial|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FOXA1 SCNN1A SOX2

7.96e-05200193b9cede2e0939c6b60ce1aa16d7efaaae79354580
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FOXA1 SCNN1A SOX2

7.96e-052001938a44a4f7ea9358f2194a490e79601c98ff7fdcb0
ToppCellSevere_COVID-19-Epithelial|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

FOXA1 SCNN1A SOX2

7.96e-0520019349910efb6d888c208cd50530b03af19f87070630
ToppCellSevere-Epithelial|Severe / Condition, Lineage, Cell class and cell subclass

FOXA1 SCNN1A SOX2

7.96e-052001936ead9db88568bb829d564a6d8e85f71fd765bac0
ToppCellmedial-2-Epithelial|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOXA1 SCNN1A SOX2

7.96e-052001930079041c3e654c1ef77c492bdb2f31ce8f4b507b
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FOXA1 SCNN1A SOX2

7.96e-0520019397f36d2c197e03d93a1fc59949d77ae90f6e6a9a
Druglavandulyl acetate

NEURL4 C2

1.98e-063192CID000030247
Drug3-n-propylphenol

NEURL4 C2

1.98e-063192CID000069302
Drug4,4'-diisothiocyanostilbene-2,2'-disulfonic acid

CLCN5 SCNN1A TARDBP C2

2.27e-05206194CID000040600
Drug1-octen-3-ol

NEURL4 C2

4.33e-0512192CID000018827
Drugceria

C2 LSS

6.88e-0515192CID000073963
DrugTMAO

SCNN1A NCOA2 TARDBP

1.54e-04127193CID000001145
Drugvasopressin

CLCN5 SCNN1A PLCD4 C2

2.63e-04388194CID011979316
Drugpyrethrin

SCNN1A NCOA2

3.02e-0431192CID000011442
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NCOA2 SETD1A SETD1B

3.76e-041721932330_DN
Drug1q54

C2 SETD1B

5.05e-0440192CID000448012
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A

CLCN5 NCOA2 LSS

5.18e-041921932450_DN
Drug0317956-0000 [391210-11-0]; Up 200; 1uM; MCF7; HT_HG-U133A

SOX2 LSS SETD1B

5.18e-041921933858_UP
DrugICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A

SCNN1A NCOA2 LSS

5.26e-041931937490_UP
DrugDiltiazem hydrochloride [33286-22-5]; Up 200; 8.8uM; PC3; HT_HG-U133A

SCNN1A SOX2 LSS

5.34e-041941936710_UP
DrugNafcillin sodium salt monohydrate [7177-50-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A

CLCN5 ZNF45 LSS

5.42e-041951933323_DN
DrugClozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A

NCOA2 SETD1A LSS

5.42e-041951935265_UP
DrugHymecromone [90-33-5]; Up 200; 22.8uM; PC3; HT_HG-U133A

SCNN1A NCOA2 SETD1A

5.50e-041961934623_UP
DrugBerberine chloride [633-65-8]; Down 200; 10.8uM; PC3; HT_HG-U133A

TPP2 ZNF45 SETD1B

5.50e-041961937143_DN
DrugHexestrol [84-16-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A

CLCN5 SETD1A LSS

5.58e-041971936077_DN
DrugBenserazide hydrochloride [14919-77-8]; Up 200; 13.6uM; PC3; HT_HG-U133A

SCNN1A NCOA2 LSS

5.58e-041971936722_UP
DrugTrichlorfon [52-68-6]; Up 200; 15.6uM; MCF7; HT_HG-U133A

SCNN1A ZNF45 SETD1B

5.58e-041971931675_UP
DrugEtilefrine hydrochloride [534-87-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A

CLCN5 NCOA2 LSS

5.58e-041971937350_UP
DrugMifepristone [84371-65-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A

SOX2 ZNF45 LSS

5.66e-041981933185_UP
DrugFlupentixol dihydrochloride cis-(Z) [2413-38-9]; Up 200; 7.8uM; HL60; HT_HG-U133A

NCOA2 ZNF45 LSS

5.66e-041981931288_UP
DrugIocetamic acid [16034-77-8]; Down 200; 6.6uM; MCF7; HT_HG-U133A

NCOA2 ZNF45 LSS

5.66e-041981933361_DN
DrugAmrinone [60719-84-8]; Up 200; 21.4uM; MCF7; HT_HG-U133A

SCNN1A LSS SETD1B

5.75e-041991936826_UP
DrugArcaine sulfate [14923-17-2]; Down 200; 14.8uM; HL60; HT_HG-U133A

CLCN5 ZNF45 LSS

5.83e-042001933010_DN
Drugcyclopropyl

NCOA2 LSS

6.39e-0445192CID000123162
Drugbumetanide

CLCN5 SCNN1A C2

6.63e-04209193CID000002471
Drugglyphosate

FOXA1 C2 LSS

7.20e-04215193CID000003496
Drugmethyl salicylate

C2 LSS

8.21e-0451192CID000004133
Diseaseneurodevelopmental disorder with speech impairment and dysmorphic facies (implicated_via_orthology)

SETD1A SETD1B

3.12e-072172DOID:0070417 (implicated_via_orthology)
DiseaseProteinuria

CLCN5 SCNN1A

2.78e-0443172C0033687

Protein segments in the cluster

PeptideGeneStartEntry
NNQMRLLGMETMAWQ

C2

351

P06681
QMNMSNVMGNTTWTT

KIAA1109

4416

Q2LD37
QSQIHNTCWAMMGLM

LSS

646

P48449
VSNMNSGLGSMNSMN

FOXA1

31

P55317
MAMWQGAMDNRGFQQ

CLCN5

1

P51795
MMTSTGNQTLYWGQM

KLF18

336

A0A0U1RQI7
MTSTGNQTLYWGQMM

KLF18

491

A0A0U1RQI7
WGQMMTSTGNQNLCG

KLF18

501

A0A0U1RQI7
KNNSNLWMSSMPGIN

SCNN1A

311

P37088
NLRSGTWMMTGNGVM

NEURL4

601

Q96JN8
TWMMTGNGVMHNGTT

NEURL4

606

Q96JN8
AHMNGWSNGSYSMMQ

SOX2

161

P48431
ELWNAGCQMVAMNMQ

PLCD4

566

Q9BRC7
MMNNTDFLMLNNPWN

TMEM191A

1

Q9H0A3
AQAALQSSWGMMGML

TARDBP

326

Q13148
QSSWGMMGMLASQQN

TARDBP

331

Q13148
SLGMNQMDMNQGSAS

SATL1

26

Q86VE3
PSLLGMNQMDMNQWS

SATL1

266

Q86VE3
GQWGGMPMSFQMQTQ

SETD1B

766

Q9UPS6
AQWGGMPMSFQMQTQ

SETD1A

671

O15047
SFQQMTWRTNMTGMA

CLEC17A

206

Q6ZS10
TNTGGMSSMNQMTGQ

NCOA2

1396

Q15596
NWTLRGTQLMNGTSM

TPP2

436

P29144
NMDIAMGWKGAQAMQ

TRMT10C

186

Q7L0Y3
WMMKMATQRDNSSGA

ZNF45

66

Q02386