Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlow voltage-gated calcium channel activity

CACNA1H CACNA1G

4.51e-053782GO:0008332
GeneOntologyCellularComponentHrd1p ubiquitin ligase complex

OS9 FAM8A1

8.00e-054772GO:0000836
GeneOntologyCellularComponentER ubiquitin ligase complex

OS9 FAM8A1

1.33e-045772GO:0000835
DomainVDCC_T_a1

CACNA1H CACNA1G

4.89e-053762IPR005445
DomainPH

KIF1A SH3BP2 RTKN ARAP1 FARP2 SOS2

3.40e-04229766PF00169
DomainKinesin_motor_CS

KIF1A KIF24 KIFC2

6.18e-0441763IPR019821
DomainKinesin-like_fam

KIF1A KIF24 KIFC2

7.11e-0443763IPR027640
DomainVDCCAlpha1

CACNA1H CACNA1G

7.20e-0410762IPR002077
DomainKINESIN_MOTOR_1

KIF1A KIF24 KIFC2

7.61e-0444763PS00411
Domain-

KIF1A KIF24 KIFC2

7.61e-04447633.40.850.10
DomainKinesin_motor_dom

KIF1A KIF24 KIFC2

7.61e-0444763IPR001752
DomainKinesin

KIF1A KIF24 KIFC2

7.61e-0444763PF00225
DomainKINESIN_MOTOR_2

KIF1A KIF24 KIFC2

7.61e-0444763PS50067
DomainKISc

KIF1A KIF24 KIFC2

7.61e-0444763SM00129
DomainPH

KIF1A SH3BP2 RTKN ARAP1 FARP2 SOS2

9.42e-04278766SM00233
DomainPH_DOMAIN

KIF1A SH3BP2 RTKN ARAP1 FARP2 SOS2

9.59e-04279766PS50003
DomainPH_domain

KIF1A SH3BP2 RTKN ARAP1 FARP2 SOS2

9.77e-04280766IPR001849
Domain-

KIF1A SH3BP2 RTKN ARHGEF17 ARAP1 FARP2 SOS2

1.06e-033917672.30.29.30
DomainHistone

H2BC20P H2BC19P SOS2

1.54e-0356763PF00125
DomainHistone_H2A/H2B/H3

H2BC20P H2BC19P SOS2

1.54e-0356763IPR007125
DomainPH_dom-like

KIF1A SH3BP2 RTKN ARHGEF17 ARAP1 FARP2 SOS2

1.73e-03426767IPR011993
DomainDH_1

ARHGEF17 FARP2 SOS2

2.16e-0363763PS00741
DomainPept_M10A_stromelysin-type

MMP25 MMP11

2.40e-0318762IPR016293
DomainRhoGEF

ARHGEF17 FARP2 SOS2

2.68e-0368763SM00325
DomainRhoGEF

ARHGEF17 FARP2 SOS2

2.91e-0370763PF00621
DomainDH_2

ARHGEF17 FARP2 SOS2

2.91e-0370763PS50010
DomainApc4_WD40_dom

WDHD1 WDR62

2.96e-0320762IPR024977
DomainANAPC4_WD40

WDHD1 WDR62

2.96e-0320762PF12894
DomainDH-domain

ARHGEF17 FARP2 SOS2

3.03e-0371763IPR000219
Domain-

ARHGEF17 FARP2 SOS2

3.03e-03717631.20.900.10
DomainH2B

H2BC20P H2BC19P

3.26e-0321762SM00427
DomainHISTONE_H2B

H2BC20P H2BC19P

3.26e-0321762PS00357
DomainHistone_H2B

H2BC20P H2BC19P

3.26e-0321762IPR000558
DomainHemopexin-like_dom

MMP25 MMP11

3.91e-0323762IPR000585
DomainPAS_fold_3

PER2 KCNH4

3.91e-0323762IPR013655
DomainPAS_3

PER2 KCNH4

3.91e-0323762PF08447
DomainHemopexin-like_repeat

MMP25 MMP11

3.91e-0323762IPR018487
DomainM10A_MMP

MMP25 MMP11

3.91e-0323762IPR033739
DomainHemopexin

MMP25 MMP11

3.91e-0323762PF00045
DomainHEMOPEXIN

MMP25 MMP11

3.91e-0323762PS00024
Domain-

MMP25 MMP11

3.91e-03237622.110.10.10
DomainHEMOPEXIN_2

MMP25 MMP11

3.91e-0323762PS51642
DomainHX

MMP25 MMP11

3.91e-0323762SM00120
DomainPept_M10A

MMP25 MMP11

3.91e-0323762IPR021190
DomainPAS-assoc_C

PER2 KCNH4

4.26e-0324762IPR000700
DomainPeptidase_M10

MMP25 MMP11

4.26e-0324762PF00413
DomainMetalloPept_cat_dom

MMP25 PAPPA MMP11

4.40e-0381763IPR024079
Domain-

MMP25 PAPPA MMP11

4.40e-03817633.40.390.10
DomainHistone-fold

H2BC20P H2BC19P SOS2

4.71e-0383763IPR009072
DomainPAC

PER2 KCNH4

4.99e-0326762IPR001610
DomainPAC

PER2 KCNH4

4.99e-0326762SM00086
DomainPAC

PER2 KCNH4

4.99e-0326762PS50113
DomainZnMc

MMP25 MMP11

6.18e-0329762SM00235
DomainPeptidase_Metallo

MMP25 MMP11

6.18e-0329762IPR006026
Domain-

CELSR1 THBS4 PAPPA

6.85e-03957632.60.120.200
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

CELSR1 RPAP1 PER2 EPOP HECTD4 SAC3D1 CACNA1H FAM110A SRCAP RNF43 KIFC2 PRRT4 ARAP1

2.11e-061105831335748872
Pubmed

Cav3.2 subunit underlies the functional T-type Ca2+ channel in murine hearts during the embryonic period.

CACNA1H CACNA1G

5.63e-06283214988077
Pubmed

Role of T-type calcium channel subunits in post-myocardial infarction remodelling probed with genetically engineered mice.

CACNA1H CACNA1G

5.63e-06283221622683
Pubmed

Ca(v)3.2 T-type Ca2+ channel-dependent activation of ERK in paraventricular thalamus modulates acid-induced chronic muscle pain.

CACNA1H CACNA1G

5.63e-06283220685979
Pubmed

T-type voltage-activated calcium channel Cav3.1, but not Cav3.2, is involved in the inhibition of proliferation and apoptosis in MCF-7 human breast cancer cells.

CACNA1H CACNA1G

5.63e-06283222469755
Pubmed

Chronic deficit in nitric oxide elicits oxidative stress and augments T-type calcium-channel contribution to vascular tone of rodent arteries and arterioles.

CACNA1H CACNA1G

5.63e-06283223436820
Pubmed

Different distribution of Cav3.2 and Cav3.1 transcripts encoding T-type Ca(2+) channels in the embryonic heart of mice.

CACNA1H CACNA1G

5.63e-06283221079360
Pubmed

High glucose induces mitochondrial dysfunction and apoptosis in human retinal pigment epithelium cells via promoting SOCS1 and Fas/FasL signaling.

SOCS1 FASLG

5.63e-06283226700587
Pubmed

Deficiency of T-type Ca2+ channels Cav3.1 and Cav3.2 has no effect on angiotensin II-induced hypertension but differential effect on plasma aldosterone in mice.

CACNA1H CACNA1G

5.63e-06283231042060
Pubmed

Clinical and genetic study of Tunisian families with genetic generalized epilepsy: contribution of CACNA1H and MAST4 genes.

MAST4 CACNA1H

5.63e-06283229948376
Pubmed

The Ca(v)3.1 T-type calcium channel is required for neointimal formation in response to vascular injury in mice.

CACNA1H CACNA1G

5.63e-06283222886848
Pubmed

Deletion of T-type calcium channels Cav3.1 or Cav3.2 attenuates endothelial dysfunction in aging mice.

CACNA1H CACNA1G

5.63e-06283229082441
Pubmed

[Decreased mRNA expressions of T-type channel alpha1H and alpha1G in the sperm of varicocele patients and their implication].

CACNA1H CACNA1G

5.63e-06283222574369
Pubmed

Blockade of T-type Ca(2+) channels inhibits human ovarian cancer cell proliferation.

CACNA1H CACNA1G

5.63e-06283221438841
Pubmed

β-Adrenergic stimulation increases Cav3.1 activity in cardiac myocytes through protein kinase A.

CACNA1H CACNA1G

5.63e-06283222808078
Pubmed

5,6-EET potently inhibits T-type calcium channels: implication in the regulation of the vascular tone.

CACNA1H CACNA1G

1.69e-05383224327205
Pubmed

Ethanol inhibition of a T-type Ca²+ channel through activity of protein kinase C.

CACNA1H CACNA1G

1.69e-05383223488970
Pubmed

Differential effect of T-type voltage-gated Ca2+ channel disruption on renal plasma flow and glomerular filtration rate in vivo.

CACNA1H CACNA1G

1.69e-05383224966091
Pubmed

T-type channels: release a brake, engage a gear.

CACNA1H CACNA1G

1.69e-05383226488564
Pubmed

Differential interactions of Na+ channel toxins with T-type Ca2+ channels.

CACNA1H CACNA1G

1.69e-05383218591418
Pubmed

Identification of the t-type calcium channel (Ca(v)3.1d) in developing mouse heart.

CACNA1H CACNA1G

1.69e-05383211230107
Pubmed

Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation.

CACNA1H CACNA1G

1.69e-05383228846697
Pubmed

Caveolin-3 regulates protein kinase A modulation of the Ca(V)3.2 (alpha1H) T-type Ca2+ channels.

CACNA1H CACNA1G

1.69e-05383221084288
Pubmed

Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures.

CACNA1H CACNA1G

1.69e-05383233547341
Pubmed

Calmodulin regulates Cav3 T-type channels at their gating brake.

CACNA1H CACNA1G

1.69e-05383228972185
Pubmed

Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability.

CACNA1H CACNA1G

1.69e-05383211927664
Pubmed

ZnT-1 enhances the activity and surface expression of T-type calcium channels through activation of Ras-ERK signaling.

CACNA1H CACNA1G

1.69e-05383222572848
Pubmed

T-type, but not L-type, voltage-gated calcium channels are dispensable for lymphatic pacemaking and spontaneous contractions.

CACNA1H CACNA1G

1.69e-05383231919478
Pubmed

Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria.

CACNA1H CACNA1G

1.69e-05383225825486
Pubmed

Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice.

CACNA1H CACNA1G

1.69e-05383211897840
Pubmed

Electric field stimulation unmasks a subtle role for T-type calcium channels in regulating lymphatic contraction.

CACNA1H CACNA1G

1.69e-05383237739992
Pubmed

Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms.

CACNA1H CACNA1G

3.37e-05483231800012
Pubmed

Unmasking early colorectal cancer clues: in silico and in vitro investigation of downregulated IGF2, SOCS1, MLH1, and CACNA1G in SSA polyps.

SOCS1 CACNA1G

3.37e-05483238874740
Pubmed

Pharmacogenetics of antiepileptic drug efficacy in childhood absence epilepsy.

CACNA1H CACNA1G

3.37e-05483228165634
Pubmed

KIFC2 is a novel neuron-specific C-terminal type kinesin superfamily motor for dendritic transport of multivesicular body-like organelles.

KIF1A KIFC2

3.37e-0548329115736
Pubmed

Functional importance of L- and P/Q-type voltage-gated calcium channels in human renal vasculature.

CACNA1H CACNA1G

3.37e-05483221788606
Pubmed

T-type Ca2+ channels elicit pro-proliferative and anti-apoptotic responses through impaired PP2A/Akt1 signaling in PASMCs from patients with pulmonary arterial hypertension.

CACNA1H CACNA1G

3.37e-05483228655554
Pubmed

Developmental expression patterns of alpha1H T-type Ca2+ channels during spermatogenesis and organogenesis in mice.

CACNA1H CACNA1G

5.60e-05583212060068
Pubmed

T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B.

CACNA1H CACNA1G

5.60e-05583229720258
Pubmed

Birth-and-death long-term evolution promotes histone H2B variant diversification in the male germinal cell line.

H2BC20P H2BC19P

8.39e-05683220194426
Pubmed

Conserved cytoplasmic domains promote Hrd1 ubiquitin ligase complex formation for ER-associated degradation (ERAD).

OS9 FAM8A1

8.39e-05683228827405
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

MAST4 PER2 SRCAP ARHGEF17

1.16e-041048349205841
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1H CACNA1G

1.17e-04783212900400
Pubmed

Molecular characterization of a novel human gene, SEC13R, related to the yeast secretory pathway gene SEC13, and mapping to a conserved linkage group on human chromosome 3p24-p25 and mouse chromosome 6.

VWF EGR4

1.56e-0488327987303
Pubmed

Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.

CACNA1H CACNA1G

1.56e-04883228330839
Pubmed

Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord.

CACNA1H CACNA1G

1.56e-04883234478646
Pubmed

Intracellular calcium plays an essential role in cardiac development.

CACNA1H CACNA1G

1.56e-04883212761855
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1H CACNA1G

2.00e-04983216382099
Pubmed

Msx1 and Msx2 are expressed in sub-populations of vascular smooth muscle cells.

MSX1 VWF

2.00e-04983218627106
Pubmed

Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity.

PAPPA CHAT IRX6

2.23e-044983335315772
Pubmed

Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage.

CACNA1H CACNA1G

2.50e-041083224778262
Pubmed

Functional characterization of a human histone gene cluster duplication.

H2BC20P H2BC19P

3.05e-041183215527963
Pubmed

The Onecut transcription factor HNF-6 regulates in motor neurons the formation of the neuromuscular junctions.

NRG2 CHAT

3.05e-041183223227180
Pubmed

Reciprocal Negative Regulation Between Lmx1a and Lmo4 Is Required for Inner Ear Formation.

MSX1 MYO15A

3.66e-041283229769265
Pubmed

The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions.

MSX1 CDT1

4.31e-041383214973489
Pubmed

Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function.

MSX1 VWF

4.31e-041383222962592
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

THBS4 KPRP PTPN23 CACNA1G FAM110A C1orf167 KIFC2 LETM1

4.44e-0475483835906200
Pubmed

Inhibition of floor plate differentiation by Pax3: evidence from ectopic expression in transgenic mice.

MSX1 CHAT

5.03e-04148328756299
Pubmed

A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development.

MSX1 PER2

5.03e-041483236213234
Pubmed

Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods.

MSX1 MMP11

6.61e-041683210075839
Pubmed

Calcium handling precedes cardiac differentiation to initiate the first heartbeat.

CACNA1H CACNA1G

7.48e-041783227725084
Pubmed

A cluster of cholinergic premotor interneurons modulates mouse locomotor activity.

PAPPA CHAT

7.48e-041783220005822
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

HROB RPAP1 WDHD1 SH3BP2 WDR81 CDT1 RTKN FAM53C FARP2

8.27e-04103883926673895
Pubmed

Inhibition of core histones acetylation by carcinogenic nickel(II).

H2BC20P H2BC19P

8.40e-041883216283522
Pubmed

Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase.

H2BC20P H2BC19P

8.40e-041883212757711
Pubmed

Lhx8 ablation leads to massive autophagy of mouse oocytes associated with DNA damage.

MSX1 MMP11

1.04e-032083229329412
Pubmed

The formation and function of the cardiac conduction system.

MSX1 CACNA1G

1.15e-032183226786210
Pubmed

β-catenin regulates Pax3 and Cdx2 for caudal neural tube closure and elongation.

MSX1 CELSR1

1.15e-032183224284205
Pubmed

Polymorphisms in the platelet-specific collagen receptor GP6 are associated with risk of nonfatal myocardial infarction in Caucasians.

THBS4 CHAT

1.15e-032183220227257
Pubmed

Functional interactions between matrix metalloproteinases and glycosaminoglycans.

MMP25 MMP11

1.26e-032283223421805
Pubmed

Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation.

MSX1 CHAT

1.26e-03228328565076
Pubmed

Matrix metalloproteinases.

MMP25 MMP11

1.26e-032283210419448
Pubmed

Endothelial PlexinD1 signaling instructs spinal cord vascularization and motor neuron development.

PAPPA CHAT

1.26e-032283236549270
Pubmed

Msx genes define a population of mural cell precursors required for head blood vessel maturation.

MSX1 VWF

1.38e-032383221693521
Pubmed

Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.

WDHD1 MRPS26 SELENOO SCO1 LETM1 WDR62

1.48e-0351583631617661
Pubmed

SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.

MMP25 EPOP DACT3 LINC00472 NRG2 C1orf167 KCNH4 ITPKB

1.54e-0391583832393512
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

PHF1 GTF3A PER2 KIF1A ATOH8 IRX6 RNF43

1.55e-0370983722988430
Pubmed

Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.

KIF1A KIFC2

1.63e-03258329275178
Pubmed

MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage.

HROB PRR18

1.63e-032583232528060
Cytoband2q37.3

PER2 KIF1A FARP2

3.92e-04778432q37.3
Cytoband17q12

STAC2 EPOP GAS2L2

8.17e-049984317q12
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

KIF1A SH3BP2 RTKN ARAP1 FARP2 SOS2

1.89e-05206496682
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF1A KIF24 KIFC2

2.62e-0446493622
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF17 FARP2 SOS2

7.59e-0466493722
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP25 MMP11

1.91e-0324492891
GeneFamilyCalcium voltage-gated channel subunits

CACNA1H CACNA1G

2.24e-0326492253
GeneFamilySulfotransferases, membrane bound

GAL3ST3 HS3ST6

4.51e-0337492763
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

MYO15A FARP2

8.11e-03504921293
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HROB WDHD1 SAC3D1 CDT1 NEURL1B KIF24 WDR62

9.31e-081998371d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCellNS-moderate-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SYCP2 CDT1 NEURL1B KIF24 TMEM200C WDR62

1.51e-06190836250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MMP25 HROB VWF NRG2 NEURL1B

7.44e-06144835f501e11b1d051ca67124137017a79a2d5bb6ae87
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

THBS4 HTR3A EGR4 MYO15A

9.00e-0670834e1ac00f4a519b6ada89f591e549874bd3eed0ca1
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

THBS4 HTR3A EGR4 MYO15A

9.00e-067083427e12c0f43a996bcbed285c5ee668bef5a786d80
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

THBS4 HTR3A EGR4 MYO15A

9.00e-0670834b6815131e87e81c10e65bc398a84dab5a74b32ac
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMP25 STAC2 WDHD1 NEURL1B KIF24

1.36e-051638357af3d3ae7e0de733a18d0486c7ffbb5a7ef7230a
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HECTD4 DACT3 PAPPA NEURL1B ARHGEF17

1.66e-051708355570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellIonocyte-iono-2|World / Class top

AMHR2 SYCP2 PAPPA NEURL1B PRR18

1.81e-05173835e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCellNS-critical-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CDT1 NEURL1B KIF24 TMEM200C WDR62

1.96e-051768357cf1a06ceee1ec06532f44c729c31b4d58e5ea49
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MSX1 VWF MAST4 WWC2-AS2 MMP11

2.02e-0517783516197068260fc062bf8b730a51a199887ea580b9
ToppCell10x5'-blood-Lymphocytic_NK-Cycling_NK|blood / Manually curated celltypes from each tissue

HROB SAC3D1 CDT1 KIF24 WDR62

2.13e-05179835c93711273055a999335ba8d0f6500e4549f46cec
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HROB WDHD1 CDT1 KIF24 WDR62

2.13e-0517983580112c686a8f85ad5e3cda6e3f3d3d51cf688092
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAC2 WDHD1 CDT1 NEURL1B KIF24

2.37e-0518383542dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMIGD2 SOCS1 SAC3D1 CDT1 WDR62

2.43e-05184835bba0138c8f7e3645a688b9a4d12f6f2134ee2c08
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMIGD2 SOCS1 SAC3D1 CDT1 WDR62

2.43e-05184835eaef1dcde60ba14e2c7fd699d01c225487256d82
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMIGD2 SOCS1 SAC3D1 CDT1 WDR62

2.43e-05184835fa73738350654066d7f9ebf78359e20ee6cbdd98
ToppCelldroplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGBL5 RTKN FAM8A1 PRRT4 WDR62

2.49e-051858356a85399cfdb9b89683c874e7f046957f9a601dc2
ToppCelldroplet-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGBL5 RTKN FAM8A1 PRRT4 WDR62

2.49e-0518583564791056cdbb739136dbef08f4b16e2b5427faad
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Cycling_T|GI_small-bowel / Manually curated celltypes from each tissue

HROB SAC3D1 CDT1 NEURL1B KIF24

2.90e-05191835e642fa7395c05fb53324c9d46bbc52f89fc9673f
ToppCellmoderate-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SYCP2 CDT1 NEURL1B KIF24 WDR62

3.13e-05194835dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCellHealthy_Control-Lymphoid-T-Proliferating_T|Healthy_Control / Condition, Lineage, Cell class and cell subclass

HROB ATOH8 SAC3D1 CDT1 NEURL1B

3.37e-051978353ce3dcbbe0edeb5a6fb5596dd6c2b4d6c1d5159d
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-NK_CD56bright|ICU-SEP / Disease, condition lineage and cell class

HROB WDHD1 TMIGD2 SOCS1 MMP11

3.37e-05197835c187e3fc2160b0165eb039cf09a6e621016068b7
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DACT3 CACNA1H NEURL1B MMP11 ARHGEF17

3.45e-051988357dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

WDHD1 MYO15A TMEM200C WDR62 ZNF513

3.45e-05198835d5e125f0c4f41b47d567568d0838adcca7655f6d
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HROB WDHD1 CDT1 KIF24 WDR62

3.62e-05200835af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCellfacs-Lung-Endomucin-24m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIANP WDHD1 PTPN23 NEURL1B

1.44e-041428340a87c0d74e281da5dc4f59e09a5e99c62b1ea801
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYCP2 DACT3 ITPKB FARP2

2.02e-04155834441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|390C / Donor, Lineage, Cell class and subclass (all cells)

EGR4 NRG2 ETNK1 KIFC2

2.02e-0415583415bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCellICU-SEP-Lymphocyte-T_NK-NK_CD56bright|ICU-SEP / Disease, Lineage and Cell Type

HROB WDHD1 TMIGD2 SOCS1

2.17e-0415883453a942cdab4a3c6813dbe11368135a24b8de1880
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MMP25 SYCP2 MIDN FAM8A1

2.33e-04161834f5da03c426f3124ea302bd343b6bca81cafee858
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MMP25 SYCP2 MIDN FAM8A1

2.39e-041628344e3bf16799c6552366d4c7e42b1328a05dcad7e7
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Pcdh11x|Hippocampus / BrainAtlas - Mouse McCarroll V32

MMP25 GAS2L2 FASLG

2.43e-0465833d90513969c0147c48403ce0155580a97f44ba716
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Pcdh11x-Inhibitory_Neuron.Gad1Gad2_Sst.Pcdh11x_(Interneuron,_OLM4_(Dentate_enriched?))-|Hippocampus / BrainAtlas - Mouse McCarroll V32

MMP25 GAS2L2 FASLG

2.43e-0465833f7f4560363bacad033154a402d7593aa5ebfb2e7
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Pcdh11x-Inhibitory_Neuron.Gad1Gad2_Sst.Pcdh11x_(Interneuron,_OLM4_(Dentate_enriched?))|Hippocampus / BrainAtlas - Mouse McCarroll V32

MMP25 GAS2L2 FASLG

2.43e-0465833d6ad7b63bc09fdc05a1245bf66d3c5a46e622ba5
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIANP TAF1C PTPN23 FASLG

2.44e-04163834a24db9d266a40f3bffe4f18d277bc269791b4560
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CELSR1 THBS4 PAPPA RTKN

2.50e-041648344cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CELSR1 THBS4 PAPPA RTKN

2.50e-041648347a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CELSR1 THBS4 PAPPA RTKN

2.50e-041648345e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCellPND10-Endothelial-Endothelial_lymphatic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CELSR1 THBS4 PAPPA RTKN

2.50e-04164834f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCell367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HROB SAC3D1 CDT1 KIF24

2.50e-04164834fb18b863152fb3109e2224c791c84c6371680a4e
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MMP25 CELSR1 NRG2 FASLG

2.50e-041648344ade97931ae1780af7836d988fe117a10b3e88a1
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VWF MAST4 WDHD1 CDT1

2.56e-0416583462457b7b74c6eae42d91d65e7dc6df6bf8e061f7
ToppCellfacs-Heart-RV-3m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASSF5 EGR4 HS3ST6 FASLG

2.62e-04166834c0fd3f3f5c3412746da279b856af0d28b9b70c5d
ToppCellfacs-Heart-RV-3m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASSF5 EGR4 HS3ST6 FASLG

2.62e-0416683433c4876df43b4c1d100699bca47459918bd054d6
ToppCellfacs-Heart-RV-3m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASSF5 EGR4 HS3ST6 FASLG

2.62e-04166834ac9b9df57d65ccbbf9ae3add50c5663efcd30dcb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WDHD1 CDT1 KIF24 WDR62

2.68e-04167834108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS4 SH3BP2 CACNA1G KIFC2

2.68e-04167834f5bffa77061baec0ba87bd688a047595f32534db
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HROB CDT1 MYO15A WDR62

2.74e-04168834de0b00bc405c898d08a06b2e585fb62c0ab9a66e
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MMP25 CELSR1 NRG2 SRCAP

2.74e-041688342fb2d916eb5000a637240d38e47a9b4f61f9f83f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HROB CDT1 KIF24 WDR62

2.80e-041698340bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HROB CDT1 KIF24 WDR62

2.80e-04169834e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-ILC3|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMP25 MAST4 EGR4 TMIGD2

2.80e-04169834d4a0bd792bddfa34332d7dc432ce253f50d98c6f
ToppCellNS-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CDT1 NEURL1B KIF24 TMEM200C

2.87e-04170834f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCellIonocyte|World / Class top

AMHR2 SYCP2 PAPPA PRR18

2.87e-04170834d2e592f2a679e6a8d32f2b752d9a3c493e50ced4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SAC3D1 CDT1 KIF24 WDR62

2.87e-0417083421bfe070e63722672176052b386167ea4c3dc4e5
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

HROB SAC3D1 CDT1 WDR62

2.93e-041718344ede6e916e593f208f2f8ccf82ef2335e061fc86
ToppCellHealthy/Control-NK_CD56bright|World / Disease group and Cell class

CELSR1 TMIGD2 SOCS1 RNF43

2.93e-0417183479d7efefdae267905af05f3001514b8b6934d86e
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MSX1 KIF1A DACT3 MMP11

3.00e-04172834de4961f4037c439d3e0ec706a257b0ec17f4d5be
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EPOP ATOH8 DACT3 NRG2

3.00e-0417283480b565f6e37f38629f4cf89d5b053b3b8517244e
ToppCellControl-MAIT|Control / Disease group and Cell class

EPOP TMIGD2 RNF43 WDR62

3.00e-04172834552bc62e8e8bb0ac1cd0452f4410a3af087787eb
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

VWF KIF1A WDR62 SOS2

3.00e-041728343b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCell10x5'-bone_marrow-Lymphocytic_NK-Cycling_NK|bone_marrow / Manually curated celltypes from each tissue

SAC3D1 CDT1 KIF24 WDR62

3.06e-041738348a9dd85f718564c07cf3120ad648daeb60c94fc5
ToppCelldroplet-Heart-HEART-1m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 WDR81 RTKN PRRT4

3.06e-041738349dc7746a84f0e268a7c061e1bbcd5e31903034dc
ToppCellfacs-MAT-Fat-18m-Lymphocytic-T_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP25 SOCS1 FAM110A RNF43

3.06e-0417383497391a763c17ce0107c9e2386e88c417ac75a72e
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIANP SCO1 CDT1 NEURL1B

3.06e-0417383415af4a0f7516dbf5c93ba66a19aca073ebe30d04
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDT1 NEURL1B KIF24 WDR62

3.13e-041748340227fea1678baa9168bd47c3b4aacb2592bb5867
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDT1 NEURL1B KIF24 WDR62

3.13e-04174834c2f8c59fca5f1ff6ffa6dc8cfce62da4b19fe9b3
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDT1 NEURL1B KIF24 WDR62

3.13e-0417483484024c04b0ce9f7068677d2d99ede56882b7dbd2
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Follicular|TCGA-Thryoid / Sample_Type by Project: Shred V9

KIF1A MRPS26 EXOC3L2 LETM1

3.20e-0417583449211b260bbe3c88354fbd1953dc06f92d3eab09
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

WDHD1 ATOH8 KIF24 WDR62

3.20e-04175834f7d191cde68de8f3457fa62b1df53b6d0dbe5001
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1-3_PAX6_NABP1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HTR3A WWC2-AS2 LINC00472 IRX6

3.20e-04175834f7f8c16e81b26748a5323d70c542d06c02eccdff
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.6.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PHF1 RASSF5 TMIGD2 DACT3

3.20e-04175834baaffc9af61f12168d6f7b96eb0b6e98a44a3909
ToppCellfacs-GAT-Fat-24m-Lymphocytic-T_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP25 SOCS1 FAM110A RNF43

3.27e-041768348caec727acae325a89a560ec44c933a635da496b
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASSF5 WDHD1 SH3BP2 CDT1

3.27e-04176834270d7908dbd84028958d257f94941dc685e20255
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SAC3D1 CDT1 PRR18 WDR62

3.34e-04177834f925a15d2162d166a5b60edac3517c6b2d6cfbea
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAC2 NRG2 CACNA1H KIF24

3.34e-0417783441cbb2c109eaa7be366fc0510cce64abc06837b4
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 SOCS1 FASLG RNF43

3.34e-041778346d86b2f97426b552dff5ce6ddf0ead1285ed618e
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 SOCS1 FASLG RNF43

3.34e-04177834d8b1bbc224d062a57a6ad40b4b2af5d6e0fe63b3
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF ATOH8 WWC2-AS2 ITPKB

3.41e-04178834360d7a987f91d6d721487a921824057ec31a7332
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF CDT1 EXOC3L2 WDR62

3.41e-04178834462111b61f37338f97ac7dc6c7da1d4316b54445
ToppCellDividing_Macrophages-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

HROB SAC3D1 FAM110A CDT1

3.41e-041788346557688c6790a5bcc3b9aea5b8789cf9506b3c54
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAST4 CHAT ITPKB FARP2

3.41e-04178834fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-TRDV2/TRGV9_gdT|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASSF5 GTF3A TMIGD2 FASLG

3.48e-04179834f7d3d37505893ae55065c89d957084602729decc
ToppCellNS-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

STAC2 VWF ATOH8 RTKN

3.48e-0417983465a96bee7bc28f5bfc20f0fd92bcc0ab2eb5e06c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDT1 NEURL1B TMEM200C WDR62

3.56e-041808340c146e80d55d18b6988dd21b1da635801bd3140c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDT1 NEURL1B TMEM200C WDR62

3.56e-04180834e9af22beae2f3c7fe213b4e19df84abfd2453433
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDT1 NEURL1B TMEM200C WDR62

3.56e-0418083411455ba704ac73f69b474845136cfecec6a88349
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDT1 NEURL1B KIF24 WDR62

3.56e-04180834334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HROB CDT1 KIF24 WDR62

3.56e-04180834f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIANP CACNA1G FAM110A ARHGEF17

3.56e-0418083478fdcfb3fdbf36469cae78407cda5bd0996930d8
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

THBS4 CACNA1H NEURL1B ARHGEF17

3.63e-0418183433cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAC2 ATOH8 CACNA1H FARP2

3.63e-04181834cd46eba2e03fd15d8de8e875793ae2f51fa98b3b
ToppCelldroplet-Marrow-BM-30m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAC2 ATOH8 CACNA1H FARP2

3.63e-04181834c7d12c7de227c9433ec2303b8929e957b833f59b
ToppCellCOVID-19-Heart-EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

THBS4 VWF CACNA1H NEURL1B

3.71e-04182834e67f3234165199085c793915ebb1f9bbd845e933
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MSX1 VWF MAST4 ATOH8

3.71e-041828340639011cdd1c437ea8b7230896a4e6e5d7244ac2
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIANP KIF1A EGR4 CACNA1H

3.71e-04182834398ce074a04f6482470b488f1affae4af7d2ec58
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

THBS4 CACNA1H NEURL1B ARHGEF17

3.79e-04183834e3835db4795362b0442d5893baf2a78efcc20428
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AMHR2 VWF NEURL1B EXOC3L2

3.79e-04183834dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AMHR2 VWF NEURL1B EXOC3L2

3.79e-041838344759560e5b4f4e5a00e5f933e3451a27c7c4aefe
DrugHydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A

PHF1 HTR3A NRG2 SRCAP MMP11 FASLG ARAP1

6.18e-061958174746_UP
DrugPyrilamine maleate [59-33-6]; Up 200; 10uM; MCF7; HT_HG-U133A

MMP25 RPAP1 TAF1C SOCS1 SRCAP ARHGEF17 SOS2

6.61e-061978177223_UP
DrugRauwolscine hydrochloride [6211-32-1]; Down 200; 10.2uM; PC3; HT_HG-U133A

PHF1 HROB MAST4 PER2 SH3BP2 TAF1C WDR62

6.61e-061978175800_DN
DrugDiphenhydramine hydrochloride [147-24-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A

MMP25 PHF1 MAST4 SH3BP2 CACNA1H SRCAP ARHGEF17

7.06e-061998176020_UP
DrugPhentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A

PHF1 MAST4 SH3BP2 TAF1C SRCAP ARAP1 ITPKB

7.06e-061998173860_DN
DrugAC1L2VU3

HTR3A CACNA1H CACNA1G

9.33e-0612813CID000129572
DrugMCI-225

HTR3A CHAT

3.74e-053812CID000131927
Drug1,3-dioxoisoindoline-5-carboxamide

CACNA1H CACNA1G

3.74e-053812CID010679219
DrugEconazole nitrate [24169-02-6]; Up 200; 9uM; MCF7; HT_HG-U133A

SYCP2 SH3BP2 TAF1C SOCS1 SRCAP SOS2

5.68e-051888167427_UP
DrugHyoscyamine (L) [101-31-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A

SH3BP2 CACNA1H SRCAP RNF43 ITPKB SOS2

6.39e-051928162271_DN
Drugclozapine; Down 200; 10uM; HL60; HT_HG-U133A

THBS4 TAF1C SRCAP MYO15A WDR62 ARAP1

6.39e-051928166188_DN
DrugBeta-sistosterol [83-46-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A

HROB MAST4 RPAP1 SH3BP2 SRCAP SOS2

6.57e-051938164154_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A

HROB CELSR1 KIF1A SH3BP2 TAF1C NRG2

6.57e-051938162721_DN
DrugTicarcillin sodium [4697-14-7]; Down 200; 9.4uM; HL60; HT_HG-U133A

THBS4 RPAP1 PER2 SH3BP2 AGBL5 ARAP1

6.96e-051958166146_DN
DrugAscorbic acid [50-81-7]; Up 200; 22.4uM; MCF7; HT_HG-U133A

SH3BP2 TAF1C CACNA1H CACNA1G WDR62 ITPKB

7.16e-051968165407_UP
DrugMeclofenamic acid sodium salt monohydrate [6385-02-0]; Down 200; 11.8uM; MCF7; HT_HG-U133A

SH3BP2 CACNA1H WDR62 ARAP1 FARP2 SOS2

7.16e-051968162291_DN
DrugProtriptyline hydrochloride [1225-55-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A

MAST4 SRCAP ARHGEF17 WDR62 ARAP1 SOS2

7.16e-051968165438_DN
DrugAlcuronium chloride [15180-03-7]; Down 200; 5.4uM; MCF7; HT_HG-U133A

MAST4 KIF1A SH3BP2 ARHGEF17 ARAP1 SOS2

7.16e-051968164409_DN
DrugChlorhexidine [55-56-1]; Up 200; 8uM; MCF7; HT_HG-U133A

MMP25 TAF1C CHAT CACNA1H SRCAP ARAP1

7.36e-051978165403_UP
DrugGuaifenesin [93-14-1]; Up 200; 20.2uM; MCF7; HT_HG-U133A

PHF1 SYCP2 PER2 TAF1C SRCAP ITPKB

7.36e-051978163431_UP
DrugVancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; PC3; HT_HG-U133A

TAF1C NRG2 SOCS1 WDR62 ARAP1 SOS2

7.36e-051978164598_UP
Drugalpha-Santonin [481-06-1]; Down 200; 16.2uM; MCF7; HT_HG-U133A

SH3BP2 CACNA1H SRCAP ARHGEF17 RNF43 FARP2

7.36e-051978163877_DN
DrugSR-95639A [115767-94-7]; Up 200; 10uM; PC3; HT_HG-U133A

PER2 EGR4 TAF1C SRCAP RNF43 SOS2

7.57e-051988166632_UP
DrugIndapamide [26807-65-8]; Up 200; 10.6uM; PC3; HT_HG-U133A

MAST4 KIF1A CHAT MMP11 FARP2 SOS2

7.57e-051988163778_UP
DrugClozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A

SYCP2 MAST4 EGR4 CACNA1G ARHGEF17 RNF43

7.57e-051988162644_UP
Drugretinoic acid; Up 200; 1uM; PC3; HT_HG-U133A

PER2 KIF1A SH3BP2 SRCAP FASLG ARHGEF17

7.78e-051998164435_UP
DrugButacaine [149-16-6]; Up 200; 13uM; PC3; HT_HG-U133A

PER2 SH3BP2 NPAP1 SRCAP ARHGEF17 RNF43

7.78e-051998165748_UP
DrugPHA-00851261E [724719-49-7]; Up 200; 1uM; MCF7; HT_HG-U133A

PHF1 THBS4 SH3BP2 PAPPA CHAT CACNA1H

8.00e-052008163968_UP
DrugAC1L1TJF

HTR3A CACNA1H CACNA1G FASLG

9.06e-0566814CID000003377
Diseaseirritable bowel syndrome (is_implicated_in)

HTR3A RNF43

7.82e-062832DOID:9778 (is_implicated_in)
Diseasecholangiocarcinoma (is_implicated_in)

WDHD1 FASLG RNF43

3.18e-0522833DOID:4947 (is_implicated_in)
Diseasemicrocephaly (implicated_via_orthology)

WDR81 ETNK1 WDR62

1.00e-0432833DOID:10907 (implicated_via_orthology)
DiseasePitt-Rogers-Danks Syndrome

MSX1 LETM1

2.16e-048832C0796117
DiseaseWolf-Hirschhorn Syndrome

MSX1 LETM1

2.78e-049832C1956097
DiseaseAutistic Disorder

HTR3A KIF1A TAF1C CACNA1H FARP2

8.63e-04261835C0004352
Diseasecarotid artery disease (is_marker_for)

VWF PAPPA

1.30e-0319832DOID:3407 (is_marker_for)
Diseasefactor VIII measurement, Ischemic stroke

VWF HECTD4

1.30e-0319832EFO_0004630, HP_0002140
Diseaseintrahepatic cholangiocarcinoma (is_marker_for)

FASLG RNF43

1.30e-0319832DOID:4928 (is_marker_for)
Diseasecoagulation factor measurement

VWF FAM110A

1.44e-0320832EFO_0004634
DiseaseLiver Failure, Acute

SCO1 FASLG

2.07e-0324832C0162557
Diseasereticulocyte count

RASSF5 STAC2 VWF FAAP20 HECTD4 SOCS1 FAM110A CDT1 EXOC3L2

2.67e-031045839EFO_0007986

Protein segments in the cluster

PeptideGeneStartEntry
RRRPPGSPCSIRDAP

nan

61

A8MZ25
PPRPRSAPAFSPISC

AGBL5

836

Q8NDL9
LARPSLACLPRPRPP

EXOC3L2

386

Q2M3D2
LACLPRPRPPSLARP

EXOC3L2

391

Q2M3D2
PAPSPAPRPAARPCR

FAM246C

166

P0DSO1
RRPLPPATCRPAGIV

C1orf167

136

Q5SNV9
PPVCPAPASRRLSAP

C9orf129

181

Q5T035
RCSPPPPPREASLAV

HTR3A

401

P46098
PRRAEPCPRVPATPR

SH3BP2

261

P78314
PCPRVPATPRRMSDP

SH3BP2

266

P78314
APPKLACRTPSPARP

CDT1

21

Q9H211
ACRTPSPARPALRAP

CDT1

26

Q9H211
TTLPACRCPPRPRPR

CELSR1

151

Q9NYQ6
LSRCPDLRPDSSPPP

AMHR2

421

Q16671
PPPDRSSRLCVPAPL

RASSF5

36

Q8WWW0
APPARPRPRSPECRM

IRX6

366

P78412
PPAAEPPPCLRRGAA

PTPN23

1101

Q9H3S7
PRCHREPPPSLRSPP

ARHGEF17

1561

Q96PE2
RPRILLCAPPARPAP

ATOH8

151

Q96SQ7
FSPRPPETRVSCLPP

FAM47C

186

Q5HY64
LDCPAPSSGPRAPRP

MMP25

506

Q9NPA2
RSLPQRPAPDPCRAP

FAAP20

116

Q6NZ36
PCPRAPRRSPSTPAP

H2BC20P

111

Q6DN03
PCPRAPRRSPSTPAP

H2BC19P

111

Q6DRA6
PPSPPLGLCHSPRRS

MYO15A

846

Q9UKN7
LRSCRGRAPARLPPP

LETM1

6

O95202
PRQPCACPATRATPP

PER2

956

O15055
LTPSRRALPGPCRRP

FAM110A

86

Q9BQ89
TQECAPPPPPRPRAR

NRG2

716

O14511
PRPISRCLARPSSPL

KIF24

1256

Q5T7B8
QLRPPCLSPCASRPP

KCNH4

931

Q9UQ05
DPVIQCRTPRPPLRP

HROB

231

Q8N3J3
RAPRSVRCGEPLPPA

EGR4

66

Q05215
RPPRPAAGPATCATR

PAPPA

36

Q13219
DCARPPPPPLQADRR

HECTD4

1921

Q9Y4D8
SPRAPECGAPALPRP

LINC00472

6

Q9H8W2
LFPLSCPPLRNSPPR

GAL3ST3

46

Q96A11
MRSPRPCGRPPTDSP

DACT3

226

Q96B18
PRTPPSPGICLRRRA

CACNA1G

2321

O43497
TRPSPRPCCVSPPLV

LINC00322

276

Q6ZN03
PRGSPCSPTPRKPCR

EPOP

16

A6NHQ4
SPPAPPRRQPCHFRN

GAS2L2

191

Q8NHY3
ARPRCPLPPEASPSR

MAST4

1951

O15021
PRPLPSFCPPRRLDQ

KPRP

376

Q5T749
ASRRSPAARPPVPAP

ETNK1

36

Q9HBU6
APALPGRTVCTRPPR

FARP2

861

O94887
PRPLRPAALPPTKCR

CACNA1H

1201

O95180
LPVPPAPPSKRHCRS

FAM53C

106

Q9NYF3
CRPRDAERPPSPRSP

SAC3D1

31

A6NKF1
CLGTRPLSTARPPPP

SCO1

61

O75880
PSRARAPATCAPPRP

PRR18

81

Q8N4B5
ACRSPPTRARPPAPL

KIFC2

716

Q96AC6
PSLRGPPTTAVPCPR

FAM8A1

26

Q9UBU6
ALPGRCPPAARAPAP

HS3ST6

46

Q96QI5
LRTPQPCSRPASPEP

KIF1A

1521

Q12756
GLPRRSAPPSPLCRS

PHF1

506

O43189
PCRPVSSAARVPPVP

MIDN

191

Q504T8
QEAPRPASSLRPPRC

MMP11

66

P24347
PASSLRPPRCGVPDP

MMP11

71

P24347
GTPCRPRAPLVLPAR

MRPS26

11

Q9BYN8
APLPPQRSPRTRGLC

RTKN

536

Q9BST9
TPPSTPSPRVPRRCY

SOS2

1261

Q07890
SPPDLASSPRCPREP

TMEM200C

301

A6NKL6
FSPPPARRLSPPACT

MSX1

151

P28360
ARLLPPPRPSCVQPL

TAF1C

491

Q15572
SPRLGRARSPSPCPF

ITPKB

166

P27987
PRTPPAPARPPCARG

PIANP

36

Q8IYJ0
CPVPLRRARPPDSSG

RNF43

431

Q68DV7
RLLPLGRCSPSPAPR

SELENOO

16

Q9BVL4
PPRCSPARERVPRPA

SRCAP

2426

Q6ZRS2
KPFCIPPRSAAPPRA

NPAP1

306

Q9NZP6
SSPAAPARPRPCPAV

SOCS1

31

O15524
RLCPHPLLRPPPSAA

OS9

226

Q13438
PIPPRRSCLPPTCFT

ARAP1

116

Q96P48
GCSPHPRAATRPPPL

CHAT

56

P28329
PPPRPPQRRCRHLVS

nan

66

P0C880
APPTRPPRRCDSNPC

THBS4

281

P35443
FRCCTPRPARPPSPT

ZNF513

241

Q8N8E2
PRQPHLASRPCPSPR

TMIGD2

231

Q96BF3
SPPSCPPHRLPTLRK

VWF

2371

P04275
PCKGSRFPPTLPRPA

WDHD1

691

O75717
RGLATPSPSPCPVPR

STAC2

86

Q6ZMT1
CSPIPRPLFLPRHTP

SYCP2

1176

Q9BX26
CGPRERPRPASSPAL

NEURL1B

261

A8MQ27
ARRPPATRPGPPTTC

nan

121

Q7L0L9
ATRPGPPTTCPPMRR

nan

126

Q7L0L9
PPTTCPPMRRWSSPR

nan

131

Q7L0L9
ARPRPPRCPTGLAAL

PRRT4

456

C9JH25
PRCPLVCVLSPPRPS

PRRT4

826

C9JH25
PSPPKRARPSPGHCL

RPAP1

71

Q9BWH6
PGTVLPCPTSVPRRP

FASLG

26

P48023
PCPTSVPRRPGQRRP

FASLG

31

P48023
QSSPPPAPPICLRRR

WDR62

31

O43379
PPRPALPRRFICSFP

GTF3A

31

Q92664
TPVRPCSRPHRAPSP

WWC2-AS2

16

Q96NR7
PCPPRGSPACPSLLR

WDR81

206

Q562E7