Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	SOX3 FOXO1 TFEB SOX11 CSRNP1 TBX3 KMT2D BARHL2 ETV5 ZNF395 MEF2D GLIS1	1.11e-05	560	93	12	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	SOX3 FOXO1 TFEB SOX11 CSRNP1 TBX3 KMT2D BARHL2 ETV5 ZNF395 MEF2D GLIS1	1.23e-05	566	93	12	GO:0001216
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	SOX3 FOXO1 TFEB SOX11 CSRNP1 TBX3 POU6F2 CUX2 KMT2D GLI3 BARHL2 ZBTB4 YLPM1 PDX1 ETV5 ZNF395 BHLHE40 MEF2D GLIS1	2.28e-05	1412	93	19	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	SOX3 FOXO1 TFEB SOX11 TBX3 POU6F2 CUX2 RBL1 GLI3 BARHL2 ZBTB4 PER1 PDX1 ETV5 ZNF395 BHLHE40 MEF2D GLIS1	1.19e-04	1459	93	18	GO:0000977
GeneOntologyMolecularFunction	beta-catenin binding	FOXO1 BCL9L DLG5 CDH22 GLI3	2.46e-04	120	93	5	GO:0008013
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SOX3 FOXO1 TFEB SOX11 TBX3 POU6F2 CUX2 GLI3 ZBTB4 PER1 PDX1 ZNF395 BHLHE40 MEF2D GLIS1	6.02e-04	1244	93	15	GO:0000978
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	FOXO1 TBX3 CUX2 ZBTB4 YLPM1 BHLHE40 GLIS1	7.42e-04	320	93	7	GO:0001227
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	SOX3 FOXO1 TFEB SOX11 TBX3 POU6F2 CUX2 GLI3 ZBTB4 PER1 PDX1 ZNF395 BHLHE40 MEF2D GLIS1	7.52e-04	1271	93	15	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	FOXO1 TBX3 CUX2 ZBTB4 YLPM1 BHLHE40 GLIS1	8.27e-04	326	93	7	GO:0001217
GeneOntologyMolecularFunction	poly(G) binding	PATL2 PATL1	9.42e-04	10	93	2	GO:0034046
GeneOntologyMolecularFunction	G-quadruplex RNA binding	PATL2 PATL1	9.42e-04	10	93	2	GO:0002151
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	SOX3 FOXO1 SOX11 TBX3 CUX2 ATN1 RBL1 GLI3 ZBTB4 YLPM1 CPEB3 PER1 PDX1 ETV5 SMARCC2 BHLHE40 GLIS1	3.07e-06	1053	91	17	GO:0000122
GeneOntologyBiologicalProcess	postsynapse organization	DLG5 CUX2 PSD CASKIN1 ITSN1 CPEB3 ETV5 SRCIN1 ZDHHC8	1.00e-05	313	91	9	GO:0099173
GeneOntologyBiologicalProcess	neuron projection development	SPTBN4 DLG5 CUX2 ARHGEF40 PSD SEMA6D GLI3 BARHL2 ITSN1 CPEB3 AUTS2 PUM2 SRCIN1 KIF5A ULK1 RERE UST PLXNB3	1.08e-05	1285	91	18	GO:0031175
GeneOntologyBiologicalProcess	regulation of postsynapse organization	CUX2 PSD CASKIN1 ITSN1 CPEB3 SRCIN1 ZDHHC8	1.79e-05	185	91	7	GO:0099175
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	SPTBN4 CUX2 ARHGEF40 SEMA6D GLI3 BARHL2 AUTS2 SRCIN1 KIF5A ULK1 RERE UST PLXNB3	2.39e-05	748	91	13	GO:0048667
GeneOntologyBiologicalProcess	regulation of synapse assembly	DLG5 CUX2 PSD CASKIN1 CPEB3 SRCIN1 ZDHHC8	3.14e-05	202	91	7	GO:0051963
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	SOX3 FOXO1 SOX11 TBX3 CUX2 ATN1 RBL1 GLI3 ZBTB4 YLPM1 CPEB3 PER1 PDX1 ETV5 SMARCC2 RERE BHLHE40 GLIS1	3.38e-05	1399	91	18	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	SOX3 FOXO1 SOX11 TBX3 CUX2 ATN1 RBL1 GLI3 ZBTB4 YLPM1 CPEB3 PER1 PDX1 ETV5 SMARCC2 RERE BHLHE40 GLIS1	3.86e-05	1413	91	18	GO:1902679
GeneOntologyBiologicalProcess	neuron projection morphogenesis	SPTBN4 CUX2 ARHGEF40 SEMA6D GLI3 BARHL2 AUTS2 SRCIN1 KIF5A ULK1 RERE UST PLXNB3	4.91e-05	802	91	13	GO:0048812
GeneOntologyBiologicalProcess	regulation of synapse organization	DLG5 CUX2 PSD CASKIN1 ITSN1 CPEB3 ETV5 SRCIN1 ZDHHC8	5.31e-05	387	91	9	GO:0050807
GeneOntologyBiologicalProcess	neuron development	SPTBN4 DLG5 CUX2 ARHGEF40 PSD SEMA6D GLI3 BARHL2 ITSN1 CPEB3 AUTS2 PUM2 SRCIN1 KIF5A ULK1 RERE UST PLXNB3	6.07e-05	1463	91	18	GO:0048666
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	SPTBN4 CUX2 ARHGEF40 SEMA6D GLI3 BARHL2 AUTS2 SRCIN1 KIF5A ULK1 RERE UST PLXNB3	6.08e-05	819	91	13	GO:0120039
GeneOntologyBiologicalProcess	regulation of synapse structure or activity	DLG5 CUX2 PSD CASKIN1 ITSN1 CPEB3 ETV5 SRCIN1 ZDHHC8	6.21e-05	395	91	9	GO:0050803
GeneOntologyBiologicalProcess	cell projection morphogenesis	SPTBN4 CUX2 ARHGEF40 SEMA6D GLI3 BARHL2 AUTS2 SRCIN1 KIF5A ULK1 RERE UST PLXNB3	6.63e-05	826	91	13	GO:0048858
GeneOntologyBiologicalProcess	cell junction organization	SPTBN4 DLG5 CUX2 CDH22 PSD CASKIN1 ITSN1 FBF1 CPEB3 ETV5 PTPN23 SRCIN1 TNS1 ZDHHC8	8.96e-05	974	91	14	GO:0034330
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	SOX3 FOXO1 TFEB SOX11 BCL9L CSRNP1 TBX3 KMT2D GLI3 BARHL2 PER1 PDX1 AUTS2 ETV5 ZNF395 MEF2D GLIS1	1.08e-04	1390	91	17	GO:0045944
GeneOntologyBiologicalProcess	axon development	SPTBN4 ARHGEF40 SEMA6D GLI3 BARHL2 AUTS2 PUM2 KIF5A ULK1 UST PLXNB3	1.21e-04	642	91	11	GO:0061564
GeneOntologyBiologicalProcess	axonogenesis	SPTBN4 ARHGEF40 SEMA6D GLI3 BARHL2 AUTS2 KIF5A ULK1 UST PLXNB3	1.96e-04	566	91	10	GO:0007409
GeneOntologyBiologicalProcess	cell junction assembly	DLG5 CUX2 CDH22 PSD CASKIN1 FBF1 CPEB3 SRCIN1 TNS1 ZDHHC8	2.04e-04	569	91	10	GO:0034329
GeneOntologyBiologicalProcess	regulation of cellular component biogenesis	SPTBN4 PATL2 DLG5 CUX2 PSD CASKIN1 CPEB3 KANK4 AUTS2 SRCIN1 ULK1 ATG2A ZDHHC8 SLX4 PLXNB3	2.08e-04	1189	91	15	GO:0044087
GeneOntologyBiologicalProcess	cell morphogenesis	SPTBN4 BCL9L CUX2 CDH22 ARHGEF40 SEMA6D GLI3 BARHL2 AUTS2 SRCIN1 KIF5A ULK1 RERE UST PLXNB3	2.18e-04	1194	91	15	GO:0000902
GeneOntologyBiologicalProcess	positive regulation of dendritic spine development	DLG5 CUX2 ITSN1 CPEB3	2.60e-04	70	91	4	GO:0060999
GeneOntologyBiologicalProcess	dendritic spine development	DLG5 CUX2 ITSN1 CPEB3 SRCIN1	4.03e-04	141	91	5	GO:0060996
GeneOntologyBiologicalProcess	synapse assembly	DLG5 CUX2 PSD CASKIN1 CPEB3 SRCIN1 ZDHHC8	4.29e-04	308	91	7	GO:0007416
GeneOntologyBiologicalProcess	regulation of nervous system development	SOX11 SRRT DLG5 CUX2 SEMA6D GLI3 ETV5 ULK1 BHLHE40 PLXNB3	4.30e-04	625	91	10	GO:0051960
GeneOntologyBiologicalProcess	regulation of cell junction assembly	DLG5 CUX2 PSD CASKIN1 CPEB3 SRCIN1 ZDHHC8	4.37e-04	309	91	7	GO:1901888
GeneOntologyBiologicalProcess	regulation of neurogenesis	SOX11 SRRT CUX2 SEMA6D GLI3 ETV5 ULK1 BHLHE40 PLXNB3	4.49e-04	515	91	9	GO:0050767
GeneOntologyCellularComponent	nuclear body	SPTBN4 SRRT FAM193B GLI3 ZBTB4 YLPM1 TOPBP1 PDX1 PTPN23 ZNF395 PATL1 RERE KMT2E BHLHE40	3.44e-05	903	91	14	GO:0016604
GeneOntologyCellularComponent	chromatin	SOX3 FOXO1 TFEB SOX11 CSRNP1 TBX3 POU6F2 CUX2 RBL1 BICRA BARHL2 PDX1 ETV5 SMARCC2 KMT2E BHLHE40 MEF2D SLX4	5.93e-05	1480	91	18	GO:0000785
GeneOntologyCellularComponent	apical dendrite	ITSN1 CPEB3 KIF5A	3.61e-04	32	91	3	GO:0097440
HumanPheno	Poor suck	SPTBN4 SOX11 SMARCC2 PTPN23 NUP214 KIF5A RERE	9.86e-06	152	27	7	HP:0002033
HumanPheno	Aplasia of the 4th metacarpal	TBX3 GLI3	2.71e-05	2	27	2	HP:0010043
HumanPheno	Small nail	SOX11 DPH2 TBX3 KMT2D BICRA SMARCC2 RERE	3.32e-05	183	27	7	HP:0001792
HumanPheno	Atrial septal defect	SOX11 DPH2 DLG5 KMT2D ATN1 BICRA GLI3 AUTS2 SMARCC2 RERE SLX4	4.66e-05	541	27	11	HP:0001631
HumanPheno	Abnormality of the atrial septum	SOX11 DPH2 DLG5 KMT2D ATN1 BICRA GLI3 AUTS2 SMARCC2 RERE SLX4	4.66e-05	541	27	11	HP:0001630
HumanPheno	Abnormal atrial septum morphology	SOX11 DPH2 DLG5 KMT2D ATN1 BICRA GLI3 AUTS2 SMARCC2 RERE SLX4	4.91e-05	544	27	11	HP:0011994
HumanPheno	Cryptorchidism	SOX3 SOX11 TBX3 POU6F2 KMT2D ATN1 BICRA GLI3 AUTS2 SMARCC2 RERE KMT2E SLX4	5.72e-05	780	27	13	HP:0000028
HumanPheno	Prominent eyelashes	SOX11 KMT2D SMARCC2	8.60e-05	17	27	3	HP:0011231
HumanPheno	Horseshoe kidney	SOX11 POU6F2 KMT2D BICRA SMARCC2 SLX4	1.01e-04	149	27	6	HP:0000085
HumanPheno	Inverted nipples	TBX3 ATN1 BICRA RERE	1.22e-04	50	27	4	HP:0003186
HumanPheno	Abnormal cardiac atrium morphology	SOX11 DPH2 DLG5 KMT2D ATN1 BICRA GLI3 AUTS2 SMARCC2 RERE SLX4	1.57e-04	617	27	11	HP:0005120
HumanPheno	Low hanging columella	SOX11 KMT2D ATN1 BICRA	1.91e-04	56	27	4	HP:0009765
HumanPheno	Abnormal localization of kidney	SOX11 POU6F2 KMT2D BICRA GLI3 SMARCC2 SLX4	1.91e-04	241	27	7	HP:0100542
HumanPheno	Aplasia/Hypoplasia of the nails	SOX11 DPH2 TBX3 KMT2D BICRA SMARCC2 RERE	2.92e-04	258	27	7	HP:0008386
HumanPheno	Abnormal spermatogenesis	SOX3 SOX11 DPH2 PATL2 TBX3 POU6F2 KMT2D ATN1 BICRA GLI3 AUTS2 SMARCC2 RERE KMT2E SLX4	2.96e-04	1190	27	15	HP:0008669
HumanPheno	Abnormal cardiac septum morphology	SOX11 DPH2 TBX3 DLG5 KMT2D ATN1 BICRA GLI3 AUTS2 SMARCC2 RERE SLX4	3.12e-04	787	27	12	HP:0001671
HumanPheno	Short 5th finger	SOX11 TBX3 KMT2D SMARCC2	3.20e-04	64	27	4	HP:0009237
HumanPheno	Tetralogy of Fallot	SOX11 KMT2D BICRA SMARCC2 RERE SLX4	3.31e-04	185	27	6	HP:0001636
HumanPheno	Aplasia/Hypoplasia of the 5th finger	SOX11 TBX3 KMT2D SMARCC2	3.61e-04	66	27	4	HP:0006262
HumanPheno	Abnormal male internal genitalia morphology	SOX3 SOX11 DPH2 PATL2 TBX3 POU6F2 KMT2D ATN1 BICRA GLI3 AUTS2 SMARCC2 RERE KMT2E SLX4	4.93e-04	1243	27	15	HP:0000022
HumanPheno	Abnormal cheek morphology	SOX11 KMT2D BICRA SH3BP2 AUTS2 RERE KMT2E	5.03e-04	282	27	7	HP:0004426
HumanPheno	Hypospadias	SOX11 POU6F2 KMT2D BICRA GLI3 SMARCC2 RERE SLX4	5.30e-04	377	27	8	HP:0000047
HumanPheno	Feeding difficulties in infancy	SPTBN4 SOX11 KMT2D SH3BP2 AUTS2 SMARCC2 PTPN23 NUP214 KIF5A RERE	5.70e-04	594	27	10	HP:0008872
HumanPheno	Cerebellar malformation	SOX11 DPH2 KMT2D ATN1 BICRA GLI3 SMARCC2 KIF5A RERE	6.03e-04	487	27	9	HP:0002438
HumanPheno	Abnormal nasal tip morphology	SOX11 KMT2D ATN1 BICRA AUTS2 SMARCC2 RERE SLX4	6.21e-04	386	27	8	HP:0000436
HumanPheno	Functional abnormality of male internal genitalia	SOX3 SOX11 DPH2 PATL2 TBX3 POU6F2 KMT2D ATN1 BICRA GLI3 AUTS2 SMARCC2 RERE KMT2E SLX4	6.26e-04	1269	27	15	HP:0000025
HumanPheno	Abnormal testis morphology	SOX3 SOX11 DPH2 TBX3 POU6F2 KMT2D ATN1 BICRA GLI3 AUTS2 SMARCC2 RERE KMT2E SLX4	6.75e-04	1129	27	14	HP:0000035
HumanPheno	Non-obstructive azoospermia	SOX3 SOX11 DPH2 TBX3 POU6F2 KMT2D ATN1 BICRA GLI3 AUTS2 SMARCC2 RERE KMT2E SLX4	6.94e-04	1132	27	14	HP:0011961
HumanPheno	Noncommunicating hydrocephalus	DLG5 BICRA	7.43e-04	8	27	2	HP:0010953
HumanPheno	Dandy-Walker malformation	SOX11 DPH2 GLI3 SMARCC2 KIF5A	7.47e-04	141	27	5	HP:0001305
HumanPheno	Displacement of the urethral meatus	SOX11 POU6F2 KMT2D BICRA GLI3 SMARCC2 RERE SLX4	7.50e-04	397	27	8	HP:0100627
HumanPheno	Abnormality of central nervous system electrophysiology	SPTBN4 SOX11 DPH2 CUX2 KMT2D ATN1 GLI3 SMARCC2 PTPN23 KIF5A RERE	7.75e-04	738	27	11	HP:0030178
HumanPheno	Abnormal male urethral meatus morphology	SOX11 POU6F2 KMT2D BICRA GLI3 SMARCC2 RERE SLX4	7.76e-04	399	27	8	HP:0032076
HumanPheno	Dolichocephaly	DPH2 KMT2D BICRA GLI3 KMT2E SLX4	8.16e-04	219	27	6	HP:0000268
HumanPheno	Hypoplastic toenails	SOX11 DPH2 TBX3 SMARCC2	8.26e-04	82	27	4	HP:0001800
HumanPheno	Ventricular septal defect	SOX11 DPH2 TBX3 DLG5 KMT2D ATN1 GLI3 SMARCC2 RERE	8.46e-04	510	27	9	HP:0001629
HumanPheno	Abnormal posterior cranial fossa morphology	SOX3 SOX11 DPH2 GLI3 SMARCC2 KIF5A	8.56e-04	221	27	6	HP:0000932
HumanPheno	Azoospermia	SOX3 SOX11 DPH2 TBX3 POU6F2 KMT2D ATN1 BICRA GLI3 AUTS2 SMARCC2 RERE KMT2E SLX4	8.77e-04	1157	27	14	HP:0000027
HumanPheno	Renal hypoplasia	TBX3 KMT2D ATN1 GLI3 RERE	9.03e-04	147	27	5	HP:0000089
HumanPheno	Giant somatosensory evoked potentials	SOX11 DPH2 GLI3 SMARCC2 KIF5A	9.03e-04	147	27	5	HP:0001312
HumanPheno	Abnormal nail morphology	SOX11 DPH2 MYOF TBX3 KMT2D BICRA GLI3 SMARCC2 RERE	9.22e-04	516	27	9	HP:0001597
HumanPheno	Abnormal male reproductive system physiology	SOX3 SOX11 DPH2 PATL2 TBX3 POU6F2 KMT2D ATN1 BICRA GLI3 AUTS2 SMARCC2 RERE KMT2E SLX4	9.32e-04	1314	27	15	HP:0012874
HumanPheno	Abnormal ventricular septum morphology	SOX11 DPH2 TBX3 DLG5 KMT2D ATN1 GLI3 SMARCC2 RERE	9.89e-04	521	27	9	HP:0010438
MousePheno	reduced female fertility	SOX3 PATL2 TBX3 CPEB3 PER1 TNFAIP3 KMT2E TNS1 SLX4 CABLES1	5.49e-06	296	78	10	MP:0001923
Domain	PAT1	PATL2 PATL1	2.25e-05	2	89	2	PF09770
Domain	Topo_II-assoc_PAT1	PATL2 PATL1	2.25e-05	2	89	2	IPR019167
Domain	Atrophin-like	ATN1 RERE	2.25e-05	2	89	2	IPR002951
Domain	Atrophin-1	ATN1 RERE	2.25e-05	2	89	2	PF03154
Domain	Sema	MST1R SEMA6D PLXNB3	4.27e-04	31	89	3	SM00630
Domain	Semap_dom	MST1R SEMA6D PLXNB3	4.27e-04	31	89	3	IPR001627
Domain	Sema	MST1R SEMA6D PLXNB3	4.27e-04	31	89	3	PF01403
Domain	SEMA	MST1R SEMA6D PLXNB3	4.27e-04	31	89	3	PS51004
Domain	PSI	MST1R SEMA6D PLXNB3	4.69e-04	32	89	3	PF01437
Domain	Plexin_repeat	MST1R SEMA6D PLXNB3	4.69e-04	32	89	3	IPR002165
Domain	PH_dom-spectrin-type	SPTBN4 PSD	7.91e-04	9	89	2	IPR001605
Domain	Homeodomain-like	POU6F2 CUX2 SEMA6D BARHL2 PDX1 SMARCC2 RERE	1.04e-03	332	89	7	IPR009057
Domain	PSI	MST1R SEMA6D PLXNB3	1.20e-03	44	89	3	IPR016201
Domain	PSI	MST1R SEMA6D PLXNB3	1.37e-03	46	89	3	SM00423
Domain	HMG_box	SOX3 SOX11 KMT2D	2.06e-03	53	89	3	PF00505
Domain	PH	SPTBN4 ARHGEF40 PSD SH3BP2 ITSN1 PLEKHA4	2.13e-03	278	89	6	SM00233
Domain	PH_DOMAIN	SPTBN4 ARHGEF40 PSD SH3BP2 ITSN1 PLEKHA4	2.17e-03	279	89	6	PS50003
Domain	HMG	SOX3 SOX11 KMT2D	2.18e-03	54	89	3	SM00398
Domain	PH_domain	SPTBN4 ARHGEF40 PSD SH3BP2 ITSN1 PLEKHA4	2.21e-03	280	89	6	IPR001849
Domain	-	SOX3 SOX11 KMT2D	2.29e-03	55	89	3	1.10.30.10
Domain	-	SPTBN4 ARHGEF40 PSD SH3BP2 ITSN1 PLEKHA4 TNS1	2.64e-03	391	89	7	2.30.29.30
Domain	HMG_box_dom	SOX3 SOX11 KMT2D	3.69e-03	65	89	3	IPR009071
Domain	SH3	DOCK5 DLG5 CASKIN1 ITSN1 RIMBP2	3.73e-03	216	89	5	SM00326
Domain	SH3	DOCK5 DLG5 CASKIN1 ITSN1 RIMBP2	3.73e-03	216	89	5	PS50002
Domain	SH3_domain	DOCK5 DLG5 CASKIN1 ITSN1 RIMBP2	4.04e-03	220	89	5	IPR001452
Domain	PH_dom-like	SPTBN4 ARHGEF40 PSD SH3BP2 ITSN1 PLEKHA4 TNS1	4.23e-03	426	89	7	IPR011993
Domain	PH	SPTBN4 PSD SH3BP2 ITSN1 PLEKHA4	4.78e-03	229	89	5	PF00169
Domain	Znf_FYVE_PHD	KMT2D ZBTB4 KMT2E PHF21B	5.36e-03	147	89	4	IPR011011
Domain	PHD	KMT2D KMT2E PHF21B	5.52e-03	75	89	3	PF00628
Domain	Znf_PHD-finger	KMT2D KMT2E PHF21B	6.37e-03	79	89	3	IPR019787
Domain	SANT_dom	SMARCC2 RERE	6.77e-03	26	89	2	IPR017884
Domain	IPT	MST1R PLXNB3	7.29e-03	27	89	2	SM00429
Domain	-	POU6F2 CUX2	7.29e-03	27	89	2	1.10.260.40
Domain	SANT	SMARCC2 RERE	7.83e-03	28	89	2	PS51293
Domain	BRCT_dom	TOPBP1 SMARCC2	7.83e-03	28	89	2	IPR001357
Domain	Nucleotide-bd_a/b_plait	SRRT RBM33 U2SURP CPEB3 CPSF7	7.83e-03	258	89	5	IPR012677
Domain	C2_dom	MYOF ITSN1 TNS1 PKN3	7.85e-03	164	89	4	IPR000008
Domain	SH3_2	CASKIN1 ITSN1 RIMBP2	8.05e-03	86	89	3	IPR011511
Domain	SH3_2	CASKIN1 ITSN1 RIMBP2	8.05e-03	86	89	3	PF07653
Domain	Lambda_DNA-bd_dom	POU6F2 CUX2	8.38e-03	29	89	2	IPR010982
Domain	PHD	KMT2D KMT2E PHF21B	8.84e-03	89	89	3	SM00249
Domain	Znf_PHD	KMT2D KMT2E PHF21B	9.40e-03	91	89	3	IPR001965
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MST1R TFEB DPH2 FAM193B MYOF ARHGEF40 KMT2D BICRA CASKIN1 ZBTB4 PER1 C15orf39 NUP214 ZNF395 ULK1 TNFAIP3 ATG2A MBD6 ZDHHC8 WNK2 PKN3 C6orf132 CABLES1	2.66e-14	1105	96	23	35748872
Pubmed	Human transcription factor protein interaction networks.	BCL9L SRRT KMT2D FAM120A ATN1 RBM33 BICRA GLI3 SEC24A YLPM1 AUTS2 ETV5 PUM2 C15orf39 SMARCC2 NUP214 PATL1 RERE MBD6 MEF2D SLX4 CPSF7	3.92e-11	1429	96	22	35140242
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	DOCK5 CUX2 ATN1 SPATA31E1 BICRA ITSN1 YLPM1 RNF38 NUP214 ATG2A KMT2E WNK2 C6orf132	2.10e-10	430	96	13	35044719
Pubmed	Interaction network of human early embryonic transcription factors.	BCL9L TBX3 KMT2D ATN1 BICRA AUTS2 C15orf39 SMARCC2 NUP214 RERE MBD6 SLX4	2.71e-10	351	96	12	38297188
Pubmed	A census of human transcription factors: function, expression and evolution.	SOX3 FOXO1 TFEB SOX11 TBX3 POU6F2 CUX2 KMT2D GLI3 BARHL2 ZBTB4 PDX1 ZNF395 RERE BHLHE40 MEF2D GLIS1	4.74e-10	908	96	17	19274049
Pubmed	A human MAP kinase interactome.	TBX3 RBM33 BICRA ITSN1 PTPN23 NUP214 KIF5A TNFAIP3 BHLHE40 TNS1 MEF2D WNK2 MAP3K4	9.30e-10	486	96	13	20936779
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	BCL9L KMT2D ATN1 RBM33 U2SURP YLPM1 SMARCC2 RERE MEF2D CPSF7	3.93e-09	268	96	10	33640491
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SRRT MYOF KMT2D ATN1 ITSN1 YLPM1 PUM2 SMARCC2 TJAP1 NUP214 PATL1 PROSER2 RERE MEF2D	2.89e-08	774	96	14	15302935
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	BCL9L KMT2D ATN1 RBM33 SEC24A YLPM1 AUTS2 PUM2 NUP214 MEF2D CPSF7	5.79e-08	457	96	11	32344865
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	GLI3 ETV5 C15orf39 KIF5A KMT2E MEF2D PHF21B WNK2	2.87e-07	233	96	8	37704626
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	SOX3 TFEB TBX3 CUX2 GLI3 BARHL2 PDX1 ETV5 BHLHE40 MEF2D GLIS1	3.30e-07	544	96	11	28473536
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	SPTBN4 SRRT ATN1 ITSN1 FBF1 PLEKHA4 SMARCC2 TJAP1 KIF5A BHLHE40 PPP1R12C	4.39e-07	560	96	11	21653829
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KLHL29 SEMA6D PUM2 RIMBP2 NUP214 ULK1 RERE PLXNB3 MAP3K4	1.99e-06	407	96	9	12693553
Pubmed	Spindle Assembly Checkpoint Inhibition Can Resensitize p53-Null Stem Cells to Cancer Chemotherapy.	KMT2D ATN1 PUM2 RIMBP2 PRR11 GLIS1	2.32e-06	137	96	6	30862715
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	EP400P1 TBX3 ARHGEF40 FAM120A PSD ATN1 RBL1 BICRA GLI3 SH3BP2 FBF1 PER1 SMARCC2 RERE	2.34e-06	1116	96	14	31753913
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	SRRT TBX3 KMT2D U2SURP YLPM1 RERE CPSF7	2.72e-06	220	96	7	35785414
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	ATN1 RBM33 BICRA AUTS2 PUM2 C15orf39	4.23e-06	152	96	6	38360978
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	FOXO1 TFEB SRRT RBM33 SEC24A SH3BP2 PER1 C15orf39 TJAP1 PATL1 PROSER2 ATG2A MEF2D	5.66e-06	1038	96	13	26673895
Pubmed	A cell cycle-regulated Slx4-Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication.	TOPBP1 SLX4	7.54e-06	2	96	2	25030699
Pubmed	Advanced glycation end-products affect transcription factors regulating insulin gene expression.	FOXO1 PDX1	7.54e-06	2	96	2	20353756
Pubmed	Protein binding of a DRPLA family through arginine-glutamic acid dipeptide repeats is enhanced by extended polyglutamine.	ATN1 RERE	7.54e-06	2	96	2	10814707
Pubmed	FoxO1 Plays an Important Role in Regulating β-Cell Compensation for Insulin Resistance in Male Mice.	FOXO1 PDX1	7.54e-06	2	96	2	26727107
Pubmed	Identification of PatL1, a human homolog to yeast P body component Pat1.	PATL2 PATL1	7.54e-06	2	96	2	17936923
Pubmed	Altered expression of MLL methyltransferase family genes in breast cancer.	KMT2D KMT2E	7.54e-06	2	96	2	23754336
Pubmed	Identification of a conserved interface between PUF and CPEB proteins.	CPEB3 PUM2	7.54e-06	2	96	2	22496444
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	DLG5 RBM33 GLI3 SEC24A ITSN1 ZDHHC8 C6orf132	8.77e-06	263	96	7	34702444
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DOCK5 SRRT TBX3 ARHGEF40 FAM120A ATN1 RBL1 C15orf39 PATL1 ULK1	1.29e-05	650	96	10	38777146
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KLHL29 SPTBN4 DOCK5 EP400P1 POU6F2 FAM120A BICRA SH3BP2 AUTS2 TJAP1 SRCIN1 PATL1 RERE GLIS1 WNK2	1.39e-05	1489	96	15	28611215
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SPTBN4 FAM120A PRR36 CASKIN1 ITSN1 YLPM1 SMARCC2 TJAP1 RIMBP2 KIF5A TNS1 WNK2	1.40e-05	963	96	12	28671696
Pubmed	Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis.	ATN1 GLI3 RERE	1.61e-05	18	96	3	14645126
Pubmed	A multistate stem cell dynamics maintains homeostasis in mouse spermatogenesis.	SOX3 PDX1 ETV5	1.91e-05	19	96	3	34686326
Pubmed	Genetic interaction of Per1 and Dec1/2 in the regulation of circadian locomotor activity.	PER1 BHLHE40	2.26e-05	3	96	2	22215611
Pubmed	Regulation of Tbx3 expression by anteroposterior signalling in vertebrate limb development.	TBX3 GLI3	2.26e-05	3	96	2	12376101
Pubmed	Sequentially acting Sox transcription factors in neural lineage development.	SOX3 SOX11	2.26e-05	3	96	2	22085726
Pubmed	Atrophin proteins interact with the Fat1 cadherin and regulate migration and orientation in vascular smooth muscle cells.	ATN1 RERE	2.26e-05	3	96	2	19131340
Pubmed	TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41.	TFEB BHLHE40	2.26e-05	3	96	2	33176151
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	BCL9L SRRT ATN1 RBM33 BICRA C15orf39 SMARCC2 CPSF7	2.42e-05	425	96	8	24999758
Pubmed	Expression of Sox transcription factors in the developing mouse pancreas.	SOX3 SOX11 PDX1	2.61e-05	21	96	3	12815626
Pubmed	A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.	SRRT PSD YLPM1 AUTS2 PUM2 NUP214 RERE CPSF7	2.67e-05	431	96	8	33660365
Pubmed	Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.	FOXO1 CDH22 SEMA6D GLI3 PLXNB3	2.71e-05	126	96	5	16284245
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	SPTBN4 U2SURP TOPBP1 PUM2 PLXNB3	3.14e-05	130	96	5	12421765
Pubmed	Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.	SRRT MYOF DLG5 FAM120A PLEKHA4 GLIS1 CPSF7	3.69e-05	329	96	7	34316702
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	FOXO1 TFEB DLG5 RBM33 ITSN1 TOPBP1 C15orf39 SLX4 CPSF7	3.73e-05	588	96	9	38580884
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SPTBN4 SRRT FAM120A PRR36 CRACDL CASKIN1 ITSN1 SMARCC2 RIMBP2 SRCIN1 TNS1 WNK2 PPP1R12C CPSF7	3.82e-05	1431	96	14	37142655
Pubmed	Identification of the human testis protein phosphatase 1 interactome.	CSRNP1 YLPM1 TOPBP1 TNS1	3.88e-05	68	96	4	21382349
Pubmed	T-box3 is a ciliary protein and regulates stability of the Gli3 transcription factor to control digit number.	TBX3 GLI3 ETV5	4.49e-05	25	96	3	27046536
Pubmed	Distinct functions of maternal and somatic Pat1 protein paralogs.	PATL2 PATL1	4.51e-05	4	96	2	20826699
Pubmed	Forkhead box O1/pancreatic and duodenal homeobox 1 intracellular translocation is regulated by c-Jun N-terminal kinase and involved in prostaglandin E2-induced pancreatic beta-cell dysfunction.	FOXO1 PDX1	4.51e-05	4	96	2	19837872
Pubmed	PBX1 and MEIS1 up-regulate SOX3 gene expression by direct interaction with a consensus binding site within the basal promoter region.	SOX3 PDX1	4.51e-05	4	96	2	19799567
Pubmed	Mosaic analysis of insulin receptor function.	FOXO1 PDX1	4.51e-05	4	96	2	14722613
Pubmed	Functional architecture of atrophins.	ATN1 RERE	4.51e-05	4	96	2	17150957
Pubmed	Dec1 and Dec2 expression is disrupted in the suprachiasmatic nuclei of Clock mutant mice.	PER1 BHLHE40	4.51e-05	4	96	2	15038852
Pubmed	Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.	FOXO1 PDX1	4.51e-05	4	96	2	12219087
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	DOCK5 VPS37C SRRT ARHGEF40 PRR36 RBM33 RBL1 ITSN1 SMARCC2 NUP214 PKN3	4.58e-05	916	96	11	32203420
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	FAM193B FAM120A GLI3 PER1 ZNF395 BHLHE40	4.64e-05	232	96	6	25515538
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	DLG5 RBM33 SEC24A ITSN1 PTPN23 PRR11 MEF2D CPSF7	5.07e-05	472	96	8	38943005
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SRRT RBM33 BICRA U2SURP YLPM1 TOPBP1 SMARCC2 NUP214 MEF2D SLX4 CPSF7	6.59e-05	954	96	11	36373674
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	KLHL29 SRRT FAM120A U2SURP YLPM1 PATL1 CPSF7	6.97e-05	364	96	7	24778252
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	FOXO1 SOX11 TBX3 CUX2 SEMA6D ETV5	7.17e-05	251	96	6	29031500
Pubmed	Iron metabolism mutant hbd mice have a deletion in Sec15l1, which has homology to a yeast gene for vesicle docking.	MYOF CPEB3	7.50e-05	5	96	2	16289749
Pubmed	TBX3 acts as tissue-specific component of the Wnt/β-catenin transcriptional complex.	BCL9L TBX3	7.50e-05	5	96	2	32808927
Pubmed	Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding.	ITSN1 KIF5A	7.50e-05	5	96	2	15256501
Pubmed	p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation.	KMT2D MEF2D	7.50e-05	5	96	2	18026121
Pubmed	Interplay between scatter factor receptors and B plexins controls invasive growth.	MST1R PLXNB3	7.50e-05	5	96	2	15184888
Pubmed	DEC1 modulates the circadian phase of clock gene expression.	PER1 BHLHE40	7.50e-05	5	96	2	18411297
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	SOX3 FOXO1 TFEB TBX3 CUX2 GLI3 ETV5 BHLHE40 MEF2D GLIS1	8.08e-05	808	96	10	20412781
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DLG5 CASKIN1 FBF1 TOPBP1 AUTS2 SRCIN1 ATG2A WNK2	1.12e-04	529	96	8	14621295
Pubmed	Control of MEF2 transcriptional activity by coordinated phosphorylation and sumoylation.	NUP214 MEF2D	1.12e-04	6	96	2	16356933
Pubmed	RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.	GLI3 GLIS1	1.12e-04	6	96	2	33895473
Pubmed	Sox gene expression during neuronal development.	SOX3 SOX11	1.12e-04	6	96	2	7821514
Pubmed	A novel gene, GliH1, with homology to the Gli zinc finger domain not required for mouse development.	GLI3 GLIS1	1.12e-04	6	96	2	12385751
Pubmed	IRIZIO: a novel gene cooperating with PAX3-FOXO1 in alveolar rhabdomyosarcoma (ARMS).	FOXO1 FAM193B	1.12e-04	6	96	2	21177767
Pubmed	Retinoic acid promotes the generation of pancreatic endocrine progenitor cells and their further differentiation into beta-cells.	PDX1 BHLHE40	1.12e-04	6	96	2	18665267
Pubmed	Expression of two type II cadherins, Cdh12 and Cdh22 in the developing and adult mouse brain.	CUX2 CDH22	1.12e-04	6	96	2	20723620
Pubmed	Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.	FOXO1 TFEB MEF2D	1.15e-04	34	96	3	25915474
Pubmed	A multipotent progenitor domain guides pancreatic organogenesis.	TBX3 PDX1 ETV5 MEF2D	1.21e-04	91	96	4	17609113
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	SRRT RBM33 BICRA YLPM1 SMARCC2 PROSER2 CPSF7	1.23e-04	399	96	7	35987950
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	FOXO1 TFEB SRRT DLG5 SEC24A TNFAIP3 PROSER2 MEF2D PPP1R12C C6orf132	1.36e-04	861	96	10	36931259
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	BCL9L RBM33 YLPM1 C15orf39 CPSF7	1.47e-04	180	96	5	35198878
Pubmed	Interplay of SOX and POU factors in regulation of the Nestin gene in neural primordial cells.	SOX3 SOX11	1.57e-04	7	96	2	15456859
Pubmed	Histone deacetylase-associating Atrophin proteins are nuclear receptor corepressors.	ATN1 RERE	1.57e-04	7	96	2	16481466
Pubmed	Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity.	ATN1 RERE	1.57e-04	7	96	2	22510986
Pubmed	Dec1 and Dec2 are regulators of the mammalian molecular clock.	PER1 BHLHE40	1.57e-04	7	96	2	12397359
Pubmed	The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth.	FOXO1 PDX1	1.57e-04	7	96	2	12488434
Pubmed	Post-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cells.	RBL1 PUM2	1.57e-04	7	96	2	25100735
Pubmed	An AUTS2-Polycomb complex activates gene expression in the CNS.	ATN1 AUTS2 RERE	1.60e-04	38	96	3	25519132
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	SRRT MYOF TBX3 DLG5 FAM120A ATN1 U2SURP SMARCC2 NUP214 PATL1 MEF2D CPSF7	1.67e-04	1247	96	12	27684187
Pubmed	The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.	TBX3 GLI3 BARHL2 ETV5 PHF21B	1.93e-04	191	96	5	24146773
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	FAM120A RBM33 ITSN1 YLPM1 PUM2 NUP214 PATL1 PRR11 PKN3	1.98e-04	733	96	9	34672954
Pubmed	Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system.	PER1 BHLHE40	2.09e-04	8	96	2	15147242
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	KMT2D KMT2E	2.09e-04	8	96	2	23130995
Pubmed	Enhancer redundancy provides phenotypic robustness in mammalian development.	TBX3 GLI3	2.09e-04	8	96	2	29420474
Pubmed	Dynamic expression of Tbx2 and Tbx3 in developing mouse pancreas.	TBX3 PDX1	2.09e-04	8	96	2	21867776
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	DOCK5 TFEB SRRT TBX3 KMT2D U2SURP YLPM1 TOPBP1 NUP214 ZNF395 BHLHE40 CPSF7	2.34e-04	1294	96	12	30804502
Pubmed	Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.	KIF5A TNFAIP3	2.68e-04	9	96	2	24449572
Pubmed	The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds.	GLI3 SMARCC2	2.68e-04	9	96	2	37805104
Pubmed	UBAP1 is a component of an endosome-specific ESCRT-I complex that is essential for MVB sorting.	VPS37C PTPN23	2.68e-04	9	96	2	21757351
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	FAM120A YLPM1 CPEB3 PUM2 NUP214 PATL1 WNK2	3.01e-04	462	96	7	31138677
Pubmed	Identification of NPM-ALK interacting proteins by tandem mass spectrometry.	CASKIN1 PDX1 MAP3K4	3.03e-04	47	96	3	14968112
Pubmed	From head to toes: the multiple facets of Sox proteins.	SOX3 SOX11	3.34e-04	10	96	2	10037800
Interaction	TOP3B interactions	MST1R TFEB DPH2 FAM193B MYOF ARHGEF40 KMT2D FAM120A RBM33 BICRA SEC24A CASKIN1 ZBTB4 PLEKHA4 PER1 C15orf39 NUP214 ZNF395 PATL1 ULK1 TNFAIP3 ATG2A MBD6 ZDHHC8 WNK2 PKN3 C6orf132 CABLES1	6.67e-11	1470	94	28	int:TOP3B
Interaction	SP7 interactions	BCL9L SRRT KMT2D ATN1 RBM33 BICRA YLPM1 C15orf39 SMARCC2 RERE MEF2D CPSF7	1.77e-08	304	94	12	int:SP7
Interaction	TLE3 interactions	SPTBN4 BCL9L SRRT TBX3 KMT2D ATN1 SEC24A ZBTB4 AUTS2 C15orf39 SMARCC2 RERE CPSF7	2.08e-08	376	94	13	int:TLE3
Interaction	GSC interactions	BCL9L TBX3 KMT2D ATN1 AUTS2 C15orf39 RERE	1.65e-07	87	94	7	int:GSC
Interaction	NUP35 interactions	BCL9L KMT2D ATN1 RBM33 SEC24A YLPM1 PLEKHA4 AUTS2 PUM2 NUP214 MEF2D CPSF7	6.48e-07	424	94	12	int:NUP35
Interaction	ALG13 interactions	KMT2D FAM120A ATN1 RBM33 PUM2 C15orf39 RERE CPSF7	2.27e-06	183	94	8	int:ALG13
Interaction	AR interactions	FOXO1 BCL9L SRRT TBX3 KMT2D ATN1 RBM33 RBL1 GLI3 U2SURP YLPM1 ETV5 SMARCC2 RERE TNS1 MEF2D CPSF7	2.99e-06	992	94	17	int:AR
Interaction	RBPMS interactions	VPS37C POU6F2 FAM120A ATN1 FBF1 PER1 SMARCC2 PATL1 BHLHE40 CPSF7	4.22e-06	340	94	10	int:RBPMS
Interaction	TSG101 interactions	VPS37C DPH2 ITSN1 YLPM1 PLEKHA4 PTPN23 NUP214 KIF5A CPSF7	1.21e-05	303	94	9	int:TSG101
Interaction	SPATA1 interactions	BICRA C15orf39 WNK2 MAP3K4	1.27e-05	31	94	4	int:SPATA1
Interaction	CRX interactions	SOX3 VPS37C BCL9L KMT2D ATN1 BICRA C15orf39 RERE	2.49e-05	254	94	8	int:CRX
Interaction	PAX9 interactions	VPS37C BCL9L KMT2D ATN1 C15orf39 MEF2D	3.28e-05	130	94	6	int:PAX9
Interaction	PRRC2B interactions	FAM120A ATN1 GLI3 PLEKHA4 PUM2 PATL1 RERE SLX4	3.37e-05	265	94	8	int:PRRC2B
Interaction	HDAC1 interactions	SRRT TBX3 KMT2D RBL1 GLI3 PLEKHA4 PDX1 C15orf39 SMARCC2 NUP214 ZNF395 RERE KMT2E BHLHE40 MEF2D PHF21B	4.98e-05	1108	94	16	int:HDAC1
Interaction	RBFOX2 interactions	DPH2 FAM120A ATN1 PLEKHA4 PUM2 RERE PKN3 CPSF7	5.50e-05	284	94	8	int:RBFOX2
Interaction	BRIP1 interactions	DOCK5 PLEKHA4 TOPBP1 POLN SLX4	7.08e-05	92	94	5	int:BRIP1
Interaction	ERG interactions	KMT2D BICRA C15orf39 SMARCC2 RERE MEF2D SLX4	8.37e-05	223	94	7	int:ERG
Interaction	KHSRP interactions	FOXO1 SEC24A YLPM1 PLEKHA4 SMARCC2 MBD6 SLX4 CPSF7	9.69e-05	308	94	8	int:KHSRP
Interaction	EGR2 interactions	BCL9L KMT2D ATN1 BICRA C15orf39 RERE	1.50e-04	171	94	6	int:EGR2
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SPTBN4 PSD SH3BP2 ITSN1 PLEKHA4	8.08e-04	206	64	5	682
Coexpression	GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	SRRT KMT2D ATN1 RBM33 BICRA SH3BP2 NUP214 MEF2D PPP1R12C CPSF7	4.71e-07	338	96	10	M17094
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_28DY_DN	SRRT PATL2 MYOF RBM33 BICRA C15orf39 SMARCC2 TJAP1 ULK1 ATG2A MBD6 BHLHE40 ZDHHC8 MEF2D PPP1R12C	1.01e-06	905	96	15	M40865
Coexpression	ZHONG_PFC_C3_ASTROCYTE	SPTBN4 SOX11 FAM193B PSD RBM33 AUTS2 RIMBP2 SRCIN1 RERE PPP1R12C	1.68e-06	389	96	10	M39102
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_7DY_DN	SRRT RBM33 BICRA SMARCC2 TJAP1 PATL1 ULK1 ATG2A MBD6 BHLHE40 ZDHHC8 MEF2D	3.55e-06	634	96	12	M40866
Coexpression	GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_IN_MAST_CELL_DN	DPH2 CSRNP1 KMT2D RBL1 ZNF395 PATL1 ULK1	6.51e-06	190	96	7	M7317
Coexpression	GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN	CSRNP1 PER1 ETV5 ZNF395 PATL1 TNFAIP3 KMT2E	8.53e-06	198	96	7	M5335
Coexpression	GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_DN	SRRT FAM193B KMT2D SRCIN1 MBD6 MEF2D MAP3K4	8.81e-06	199	96	7	M7319
Coexpression	GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_DN	FOXO1 FAM120A CRACDL ITSN1 RNF38 MEF2D CPSF7	9.10e-06	200	96	7	M291
Coexpression	GSE6092_CTRL_VS_BORRELIA_BIRGDOFERI_INF_ENDOTHELIAL_CELL_DN	MST1R PSD ITSN1 PER1 TNFAIP3 MEF2D	1.86e-05	149	96	6	M6708
Coexpression	GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TREG_CD4_TCELL_DN	BICRA PATL1 RERE MBD6 UST MEF2D	2.32e-05	155	96	6	M8944
Coexpression	GRADE_COLON_VS_RECTAL_CANCER_DN	C15orf39 ULK1 KMT2E CPSF7	5.36e-05	56	96	4	M9435
Coexpression	LIU_PROSTATE_CANCER_DN	KLHL29 MYOF ARHGEF40 SEMA6D RBM33 U2SURP ZNF395 TNS1 GLIS1	8.35e-05	493	96	9	M19391
Coexpression	GSE16266_CTRL_VS_LPS_STIM_MEF_UP	TFEB ARHGEF40 CRACDL SH3BP2 ZBTB4 SLX4	9.08e-05	198	96	6	M7219
Coexpression	GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN	EP400P1 ZNF395 PATL1 TNFAIP3 ATG2A KMT2E	9.34e-05	199	96	6	M5348
Coexpression	GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN	DLG5 CPEB3 AUTS2 ATG2A MBD6 BHLHE40	9.34e-05	199	96	6	M6519
Coexpression	GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN	DPH2 FAM120A SH3BP2 ETV5 BHLHE40 PHF21B	9.60e-05	200	96	6	M7771
Coexpression	GSE26030_TH1_VS_TH17_RESTIMULATED_DAY5_POST_POLARIZATION_DN	FAM120A BICRA ZBTB4 MEF2D PLXNB3 MAP3K4	9.60e-05	200	96	6	M8574
Coexpression	GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TREG_CD4_TCELL_DN	TFEB FAM193B KMT2D ATG2A MBD6	1.62e-04	139	96	5	M8948
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXO1 BCL9L CSRNP1 ATN1 PER1 PPP1R12C	3.13e-06	186	96	6	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MST1R MYOF CRACDL RIMBP2 PROSER2 C6orf132	3.23e-06	187	96	6	87b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK5 FOXO1 GLI3 SH3BP2 PHF21B CABLES1	3.23e-06	187	96	6	4d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MST1R MYOF CRACDL RIMBP2 PROSER2 C6orf132	3.23e-06	187	96	6	42a1267bfc27b4460b8409ada580a87c4385841c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MST1R MYOF CRACDL RIMBP2 PROSER2 C6orf132	3.23e-06	187	96	6	64afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCell	COVID-19_Mild-Lymphoid_T/NK-gd_T\|COVID-19_Mild / Disease group, lineage and cell class	BCL9L PATL2 AUTS2 TNFAIP3 ATG2A BHLHE40	4.49e-06	198	96	6	6aea5d00c417708f05b6d2dfe5a962d80864f8eb
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-gd_T\|COVID-19_Mild / Disease, condition lineage and cell class	BCL9L PATL2 AUTS2 TNFAIP3 ATG2A BHLHE40	4.76e-06	200	96	6	6560753d3df2f87860b52052d4881aa45410f666
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	SOX11 DLG5 POU6F2 ATN1 AUTS2 WNK2	4.76e-06	200	96	6	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BCL9L PATL2 AUTS2 TNFAIP3 ATG2A BHLHE40	4.76e-06	200	96	6	109f673a4967ffa52270a0b4f818b3461288db44
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Krt80\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CDH22 PROSER2 BHLHE40 TNS1 UST	1.37e-05	141	96	5	40ef6d792e11fe10963d64eb0b606b90556c1a70
ToppCell	3'_v3-blood-Lymphocytic_T_CD8-Trm_gut_CD8\|blood / Manually curated celltypes from each tissue	PSD PRR36 ZBTB4 AUTS2 CABLES1	1.97e-05	152	96	5	1fea735321da6db6d2cd3f83d2f7fac72d44904d
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Agmat\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CUX2 CDH22 CRACDL PLEKHA4 PROSER2	2.23e-05	156	96	5	09e0702400570089d9012dcf94dfb4827c97e49d
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KLHL29 DOCK5 FOXO1 SEMA6D GLI3	3.18e-05	168	96	5	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	droplet-Marrow-BM-1m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOF SH3BP2 PER1 AUTS2 C6orf132	3.18e-05	168	96	5	2e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	POU6F2 CUX2 CDH22 SEMA6D CRACDL	3.27e-05	169	96	5	319cba07263bf41fcbcbfecd117f91b729394241
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SPTBN4 CRACDL RIMBP2 PHF21B WNK2	3.27e-05	169	96	5	96a2aec9acf8a6f966973c035e5ade456cf47772
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SPTBN4 RIMBP2 KIF5A PHF21B WNK2	3.27e-05	169	96	5	b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCell	wk_15-18-Epithelial-PNS-Schwann_precursor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KLHL29 KMT2D CASKIN1 AUTS2 PHF21B	4.07e-05	177	96	5	5357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCell	IIF-Lymphocyte-T_NK-MAIT\|IIF / Disease, Lineage and Cell Type	CSRNP1 TNFAIP3 ATG2A KMT2E BHLHE40	4.19e-05	178	96	5	be777ebef8f09a1a16fcee8fc69a65ab295b6e1d
ToppCell	RV-11._Adipocyte\|RV / Chamber and Cluster_Paper	KLHL29 FOXO1 ITSN1 KANK4 CABLES1	4.19e-05	178	96	5	278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 CUX2 PRR36 RIMBP2 SRCIN1	4.65e-05	182	96	5	be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDH22 CASKIN1 ETV5 UST CABLES1	4.77e-05	183	96	5	25c96df8ea0c7bbedbb7699ee84ad6234d19cba8
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN4 TFEB SEMA6D CPEB3 PHF21B	4.90e-05	184	96	5	e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDH22 CASKIN1 ETV5 UST CABLES1	5.03e-05	185	96	5	dbbd348714cd16a4948a04648e914b1e71e2a8ef
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDH22 CASKIN1 ETV5 UST CABLES1	5.03e-05	185	96	5	bea69058afa5aa927fe15c1f8d46460562ec4dd4
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	DOCK5 ITSN1 PER1 ATG2A KMT2E	5.29e-05	187	96	5	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 GLI3 SH3BP2 PHF21B PLXNB3	5.29e-05	187	96	5	5d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 GLI3 SH3BP2 PHF21B PLXNB3	5.29e-05	187	96	5	5c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYOF SEMA6D CRACDL RIMBP2 PHF21B	5.29e-05	187	96	5	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	RA-11._Adipocyte\|World / Chamber and Cluster_Paper	KLHL29 FOXO1 ITSN1 KANK4 CABLES1	5.43e-05	188	96	5	4dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCell	facs-Skin-nan-18m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSRNP1 TJAP1 TNFAIP3 BHLHE40 WNK2	5.56e-05	189	96	5	6c71e81373cb7822de23c193a6350b6df9f567bc
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSRNP1 TJAP1 TNFAIP3 PROSER2 BHLHE40	5.56e-05	189	96	5	1cfc1fe27c4b57b4e52700fa8f679ce172cee5a9
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 GLI3 SH3BP2 PHF21B PLXNB3	5.70e-05	190	96	5	5c64b727669b23d2a23c8ad1d5d6caab7af37d56
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 GLI3 SH3BP2 PHF21B PLXNB3	5.70e-05	190	96	5	3a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK5 FOXO1 GLI3 PHF21B PLXNB3	5.70e-05	190	96	5	2de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 GLI3 SH3BP2 PHF21B PLXNB3	5.70e-05	190	96	5	1c3d601422efa60fad8565f9ccd9032b847e4a91
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 GLI3 SH3BP2 PHF21B CABLES1	5.99e-05	192	96	5	43beaac1de99b9c1a6dab4a450b4e81286987b64
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOCK5 SOX11 GLI3 ETV5 RERE	6.30e-05	194	96	5	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOCK5 SOX11 TBX3 ETV5 UST	6.30e-05	194	96	5	fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCell	mild_COVID-19-CD4+_CTL\|World / disease group, cell group and cell class (v2)	PATL2 AUTS2 TNFAIP3 BHLHE40 GLIS1	6.45e-05	195	96	5	980909246c30471c9f2f97c3b20b6d6d20fe574e
ToppCell	mild_COVID-19\|World / disease group, cell group and cell class (v2)	CSRNP1 AUTS2 TNFAIP3 KMT2E BHLHE40	6.45e-05	195	96	5	6dbe9db5f0e94f2e91b3d1282855d200051ab0ba
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DOCK5 SOX11 GLI3 ETV5 RERE	6.45e-05	195	96	5	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-Trm_Th1/Th17\|Liver / Manually curated celltypes from each tissue	FOXO1 CSRNP1 PER1 TNFAIP3 BHLHE40	6.45e-05	195	96	5	480cc62ee1e5b1aaf6b62be6e5afd7a81236a1b0
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-gd_T\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	BCL9L PATL2 AUTS2 TNFAIP3 ATG2A	6.61e-05	196	96	5	aec2b11a6048048820271266fdc8b8d806da9993
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-gd_T-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	BCL9L PATL2 AUTS2 TNFAIP3 ATG2A	6.61e-05	196	96	5	aa0dc04f94a575cd442ee473b75a4f54268e4105
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-gd_T-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BCL9L PATL2 AUTS2 TNFAIP3 ATG2A	6.61e-05	196	96	5	502834a16d5ada93af7ab9af0c3dc652086964bd
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-gd_T\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BCL9L PATL2 AUTS2 TNFAIP3 ATG2A	6.61e-05	196	96	5	ae9bf04531b9bda819608d90736c4405a6c3df41
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD8-Tem/emra_CD8\|bone_marrow / Manually curated celltypes from each tissue	SRRT PATL2 AUTS2 ATG2A BHLHE40	6.61e-05	196	96	5	f23c33ad10f933250be98e8389a9aa278e876f96
ToppCell	Control-Lymphoid_T/NK-gd_T\|Control / Disease group, lineage and cell class	BCL9L PATL2 AUTS2 TNFAIP3 ATG2A	6.61e-05	196	96	5	98b11aada6bc5d928ef618573dc912d4d74a1092
ToppCell	lymphoid-T_cell-unlabelled(multiplets)\|T_cell / Lineage, cell class and subclass	CSRNP1 PER1 TNFAIP3 ATG2A BHLHE40	6.77e-05	197	96	5	f215435aee15f0ed254104bfd55670144b6d2ac3
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BCL9L PATL2 AUTS2 TNFAIP3 ATG2A	6.93e-05	198	96	5	a1b310274aa9b3d2aa1fe9488d67422bf4ac81d2
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 CUX2 SRCIN1 KIF5A PHF21B	6.93e-05	198	96	5	85881637641d8996be2edc65c4bceff0433135e7
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BCL9L PATL2 AUTS2 TNFAIP3 ATG2A	6.93e-05	198	96	5	76aff381403bc5a8a9cc73eb1e5dbdc0bac7de6c
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	BCL9L PATL2 AUTS2 TNFAIP3 ATG2A	6.93e-05	198	96	5	a781fd35a7cda8b7760c2e3ddccaac7aac26c979
ToppCell	control-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DOCK5 TFEB MYOF ARHGEF40 C15orf39	6.93e-05	198	96	5	35499a5231818e3432cf69b5c4a58c02f7771db8
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	BCL9L PATL2 AUTS2 TNFAIP3 ATG2A	6.93e-05	198	96	5	df399674345c45738d765a8354ea8d1484572c34
ToppCell	control-HLA-DR+_CD83+_Monocyte\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DOCK5 TFEB MYOF ARHGEF40 C15orf39	7.10e-05	199	96	5	f1b370d2869ad29c9d8ff41fdcc486fffa781ee2
ToppCell	mLN-ILC-ILC\|mLN / Region, Cell class and subclass	DOCK5 ARHGEF40 CRACDL TNFAIP3 BHLHE40	7.10e-05	199	96	5	ab09a06cdea2597e9fe4b4b304655e9de4d433f6
ToppCell	mLN-ILC\|mLN / Region, Cell class and subclass	DOCK5 ARHGEF40 CRACDL TNFAIP3 BHLHE40	7.10e-05	199	96	5	d6c299312c747fb1b7c53644c53efc03a5fffe85
ToppCell	mLN-(3)_ILC\|mLN / shred on region, Cell_type, and subtype	DOCK5 ARHGEF40 CRACDL TNFAIP3 BHLHE40	7.10e-05	199	96	5	00e0e2a766dd9c4d0a65f53d88fa50df4b6a3d60
ToppCell	mLN-(3)_ILC-(30)_ILC\|mLN / shred on region, Cell_type, and subtype	DOCK5 ARHGEF40 CRACDL TNFAIP3 BHLHE40	7.10e-05	199	96	5	33ac6d77099076df01299be429f4ba96f2f34cc1
ToppCell	Macroglial-Astrocytes-SLC14A1---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GLI3 SH3BP2 ITSN1 PHF21B CABLES1	7.27e-05	200	96	5	d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCell	Macroglial-Astrocytes-SLC14A1----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GLI3 SH3BP2 ITSN1 PHF21B CABLES1	7.27e-05	200	96	5	f861509b54185d89931db64da1b9d81986cc7938
ToppCell	mild-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DOCK5 MYOF ARHGEF40 SH3BP2 PER1	7.27e-05	200	96	5	934c2efc780318c66d667ca75be0de350361d351
ToppCell	MS-IIF-Lymphocyte-T/NK-MAIT\|IIF / Disease, condition lineage and cell class	CSRNP1 TNFAIP3 ATG2A KMT2E BHLHE40	7.27e-05	200	96	5	7518bbf1c713b74f89be25ee700c6b0edc16ee8a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial-Astrocyte\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	SOX3 TBX3 BICRA GLI3 ETV5	7.27e-05	200	96	5	98a994692440cb4f505b050276f0c8022c814a21
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	YLPM1 TOPBP1 PER1 TNFAIP3 MBD6	7.27e-05	200	96	5	0d76b006d8e8b32174e65e400acd0674354b962c
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Mesenchymal-Mesoderm\|1m / Sample Type, Dataset, Time_group, and Cell type.	SEC24A PLEKHA4 PROSER2 ATG2A BHLHE40	7.27e-05	200	96	5	c0ad32e9dd7f481c2665587fd8bd9fffc2e725f9
ToppCell	Macroglial-Astrocytes-SLC14A1\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GLI3 SH3BP2 ITSN1 PHF21B CABLES1	7.27e-05	200	96	5	16f468217427921fa18c6d078ffa990eb019b257
ToppCell	MS-IIF\|MS / Disease, condition lineage and cell class	RBL1 PER1 TNFAIP3 ATG2A TNS1	7.27e-05	200	96	5	221f59edcfc18baece13184c2552d26022228146
ToppCell	Control-Control-Lymphocyte-T/NK-gd_T\|Control / Disease, condition lineage and cell class	BCL9L PATL2 AUTS2 TNFAIP3 ATG2A	7.27e-05	200	96	5	88e502c141bbb73e62aa5830d24bd645376e5f3a
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Myeloid\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	YLPM1 TOPBP1 PER1 TNFAIP3 MBD6	7.27e-05	200	96	5	cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
ToppCell	Macroglial-Astrocytes-SLC14A1--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GLI3 SH3BP2 ITSN1 PHF21B CABLES1	7.27e-05	200	96	5	0442894c39eec69850c090957a5dc7bcecd21e04
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	SOX3 TBX3 BICRA GLI3 ETV5	7.27e-05	200	96	5	ef222dc4a205d670172dae74990bdb952ac92e5b
ToppCell	COVID-19-COVID-19_Mild\|COVID-19 / Disease, condition lineage and cell class	SH3BP2 PER1 TNFAIP3 KMT2E BHLHE40	7.27e-05	200	96	5	62c25042086f1afd1102e0720e933c2e476468fd
ToppCell	Macroglial-Astrocytes-SLC14A1-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GLI3 SH3BP2 ITSN1 PHF21B CABLES1	7.27e-05	200	96	5	01819446deeab9054f5cfe889d53bb49d137dbc0
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRACDL SH3BP2 CPEB3 ULK1	1.09e-04	114	96	4	84318a25a701331ccd5e68221239c543b9c0cc54
ToppCell	NS-moderate-d_16-33-Epithelial-unknown_epithelial\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RBL1 PLEKHA4 RERE PPP1R12C	2.20e-04	137	96	4	03e124901a0e85b59b6882bbafab568b50907e8b
ToppCell	moderate-Epithelial-unknown_epithelial\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RBL1 PLEKHA4 RERE PPP1R12C	2.26e-04	138	96	4	afefa8233c67aa744e939156bc538449bf6bd05b
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CDH22 PROSER2 BHLHE40 TNS1	2.39e-04	140	96	4	7cc891d676555609add6fc7880735d948a2ad801
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Macc1_Lrg1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CUX2 CDH22 CRACDL BHLHE40	2.52e-04	142	96	4	d08e1880425d285c4433014fe0242ac7ff7734af
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-Trm_Th1/Th17\|bone_marrow / Manually curated celltypes from each tissue	FOXO1 TNFAIP3 BHLHE40 GLIS1	3.03e-04	149	96	4	264fe2ceac6379b3394d2bb47ef34692e4a64559
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|lymph-node_spleen / Manually curated celltypes from each tissue	DOCK5 PRR36 SRCIN1 CABLES1	3.52e-04	155	96	4	b0e456c4915076e1d38282e116a6eb3230ae80dc
ToppCell	Healthy_Control-Myeloid-Macrophages-FCN1_high\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	MYOF GLI3 PLEKHA4 PROSER2	3.52e-04	155	96	4	cd2ccb4632713b4def3a1064599b78207e2e44c0
ToppCell	CD8+_Memory_T_cell-RSV-6\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	DLG5 ZNF395 ZDHHC8 PKN3	3.78e-04	158	96	4	5ae737757a49fc96bde1e57e02066f9f65654ea1
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POLN UBE2Q2 WNK2 PLXNB3	3.97e-04	160	96	4	f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCell	droplet-Lung-nan-3m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TOPBP1 KIF5A PROSER2 PRR11	3.97e-04	160	96	4	8a7a73b0ee1877fe02d47f745d36ae2858b529e1
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX11 PRR36 AUTS2 PHF21B	4.06e-04	161	96	4	bd520c9a1927d5d5355b4421e6b90b58bfb76a42
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA6D CRACDL RIMBP2 KIF5A	4.06e-04	161	96	4	4bb7bae54ba3bdf46b525c01f5ad3db8e49819cb
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-ILC3\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CSRNP1 CRACDL TNFAIP3 BHLHE40	4.06e-04	161	96	4	584e44e6048c2678eb72cd23a86f48f2466c5da4
ToppCell	5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-EECs\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN4 PSD RIMBP2 SRCIN1	4.16e-04	162	96	4	478cf560ef33c5c324142c76417447d4a571a2c9
ToppCell	facs-Heart-RA-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX3 POU6F2 CUX2 WNK2	4.16e-04	162	96	4	3a61eda548afa2a41bdf6293d1050103dc210e52
ToppCell	facs-Heart-RA-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX3 POU6F2 CUX2 WNK2	4.16e-04	162	96	4	593939be9d38690c89c31d4c58e351de26cbf9ab
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CUX2 PLEKHA4 BHLHE40 PHF21B	4.26e-04	163	96	4	1e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CUX2 PLEKHA4 BHLHE40 PHF21B	4.26e-04	163	96	4	431221a41d396b09170476179590eaf8a55266d8
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MST1R TFEB SH3BP2 UST	4.36e-04	164	96	4	54f8f11d2fa899005530c08e7a1ee728c7b0799c
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SPTBN4 RIMBP2 KIF5A PHF21B	4.36e-04	164	96	4	be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell	10x5'-blood-Lymphocytic_Invariant-Inducer-like-ILC3\|blood / Manually curated celltypes from each tissue	DLG5 PRR36 CPEB3 PROSER2	4.46e-04	165	96	4	f012a27ece54c0f7b73a2f4f89c6ee8b865f8782
ToppCell	COVID-19_Mild-PLT_0\|COVID-19_Mild / Disease Group and Platelet Clusters	DOCK5 ATN1 PLEKHA4 PRR11	4.46e-04	165	96	4	083a14d3b0162cee4e79f7398b8fb739582b39ff
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SOX3 PRR11 XKR5 PLXNB3	4.56e-04	166	96	4	a7ac5a414e3e2ff01f1c452c0a85048b17cba0b6
Computational	Genes in the cancer module 257.	SRRT KMT2D FBF1 ZDHHC8 MEF2D CPSF7	1.67e-04	156	57	6	MODULE_257
Drug	Niclosamide [50-65-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A	MYOF PER1 AUTS2 ETV5 ULK1 TNFAIP3 RERE BHLHE40	3.28e-07	158	95	8	4136_UP
Drug	pyrvinium pamoate; Up 200; 1.25uM; MCF7; HT_HG-U133A_EA	DOCK5 FOXO1 SH3BP2 PER1 ETV5 ULK1 TNFAIP3 BHLHE40	5.73e-07	170	95	8	978_UP
Drug	fluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A	MYOF PRR36 GLI3 YLPM1 AUTS2 ETV5 TNFAIP3 BHLHE40	1.28e-06	189	95	8	6954_UP
Drug	Myricetin [529-44-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A	DOCK5 MYOF PRR36 SH3BP2 ETV5 TJAP1 RERE MAP3K4	1.61e-06	195	95	8	4170_DN
Drug	Etodolac [41340-25-4]; Down 200; 14uM; PC3; HT_HG-U133A	MST1R MYOF GLI3 YLPM1 C15orf39 SMARCC2 TNFAIP3 TNS1	1.88e-06	199	95	8	7246_DN
Drug	Talampicillin hydrochloride [39878-70-1]; Down 200; 7.8uM; PC3; HT_HG-U133A	SRRT MYOF RBL1 U2SURP ETV5 C15orf39 SMARCC2 TNS1	1.88e-06	199	95	8	7254_DN
Drug	Syrosingopine [84-36-6]; Up 200; 6uM; MCF7; HT_HG-U133A	MYOF ARHGEF40 SH3BP2 PER1 ETV5 TNFAIP3 BHLHE40	9.82e-06	178	95	7	2753_UP
Drug	felodipine; Up 200; 10uM; MCF7; HT_HG-U133A_EA	KLHL29 GLI3 PER1 ETV5 TJAP1 TNFAIP3 BHLHE40	1.14e-05	182	95	7	848_UP
Drug	Metaraminol bitartrate [33402-03-8]; Up 200; 8.6uM; PC3; HT_HG-U133A	KLHL29 MST1R TFEB PER1 ETV5 TJAP1 TNS1	1.35e-05	187	95	7	7368_UP
Drug	Amitryptiline hydrochloride [549-18-8]; Up 200; 12.8uM; PC3; HT_HG-U133A	KLHL29 FOXO1 MYOF BICRA ETV5 TNFAIP3 UST	1.61e-05	192	95	7	6353_UP
Drug	Tribenoside [10310-32-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A	TFEB ATN1 AUTS2 ETV5 TNFAIP3 TNS1 MEF2D	1.72e-05	194	95	7	3507_UP
Drug	2-propylpentanoic acid; Down 200; 50uM; HL60; HT_HG-U133A	DLG5 RBL1 BICRA SH3BP2 ETV5 ULK1 RERE	1.78e-05	195	95	7	1163_DN
Drug	GSK-3 Inhibitor IX; Up 200; 0.5uM; MCF7; HT_HG-U133A	VPS37C SRRT MYOF ATN1 PRR36 SH3BP2 U2SURP	1.78e-05	195	95	7	7101_UP
Drug	Boldine [476-70-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A	SRRT DLG5 CPEB3 TJAP1 NUP214 KIF5A RERE	1.83e-05	196	95	7	4122_DN
Drug	Loperamide hydrochloride [34552-83-5]; Up 200; 7.8uM; HL60; HG-U133A	DOCK5 BICRA GLI3 YLPM1 ETV5 TJAP1 MEF2D	1.83e-05	196	95	7	2033_UP
Drug	Thiethylperazine malate [52239-63-1]; Up 200; 6uM; MCF7; HT_HG-U133A	ATN1 SEMA6D SH3BP2 NUP214 RERE BHLHE40 UST	1.83e-05	196	95	7	6232_UP
Drug	Acetopromazine maleate salt [3598-37-6]; Up 200; 9uM; MCF7; HT_HG-U133A	SRRT SEMA6D SH3BP2 ETV5 NUP214 TNS1 MEF2D	1.83e-05	196	95	7	6832_UP
Drug	Dihydrostreptomycin sulfate [5490-27-7]; Up 200; 2.8uM; MCF7; HT_HG-U133A	DOCK5 TFEB SEMA6D SEC24A SH3BP2 NUP214 TNS1	1.90e-05	197	95	7	2237_UP
Drug	0173570-0000 [211245-44-2]; Up 200; 1uM; PC3; HT_HG-U133A	ATN1 PER1 ETV5 TJAP1 NUP214 RERE BHLHE40	1.96e-05	198	95	7	7391_UP
Drug	rotenone; Down 200; 1uM; MCF7; HT_HG-U133A	TFEB ARHGEF40 RBL1 U2SURP AUTS2 C15orf39 TNS1	1.96e-05	198	95	7	5915_DN
Drug	Naloxone hydrochloride [357-08-4]; Up 200; 11uM; HL60; HG-U133A	SRRT MYOF BICRA ITSN1 YLPM1 ETV5 MEF2D	1.96e-05	198	95	7	2006_UP
Drug	thioridazine hydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A_EA	PRR36 PER1 ETV5 TNFAIP3 BHLHE40 MEF2D	4.94e-05	156	95	6	1010_UP
Drug	Pimozide [2062-78-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A	SH3BP2 PER1 ETV5 TJAP1 TNFAIP3 BHLHE40	6.98e-05	166	95	6	6780_UP
Drug	felodipine; Up 200; 10uM; MCF7; HT_HG-U133A_EA	FOXO1 PRR36 YLPM1 PER1 TNFAIP3 BHLHE40	7.96e-05	170	95	6	965_UP
Drug	prochlorperazine dimaleate salt; Up 200; 10uM; MCF7; HT_HG-U133A_EA	FOXO1 SH3BP2 PER1 TJAP1 TNFAIP3 BHLHE40	8.77e-05	173	95	6	995_UP
Drug	Chlorpromazine hydrochloride [69-09-0]; Up 200; 11.2uM; PC3; HT_HG-U133A	CPEB3 PER1 ETV5 TJAP1 TNFAIP3 RERE	1.06e-04	179	95	6	5074_UP
Drug	Nocodazole [31430-18-9]; Up 200; 13.2uM; MCF7; HT_HG-U133A	VPS37C PRR36 SH3BP2 ETV5 TJAP1 BHLHE40	1.30e-04	186	95	6	6793_UP
Drug	Methyl benzethonium chloride [25155-18-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A	MST1R CUX2 SH3BP2 PER1 TNFAIP3 BHLHE40	1.34e-04	187	95	6	3943_UP
Drug	Betulinic acid [472-15-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A	VPS37C MYOF SH3BP2 PER1 TNFAIP3 BHLHE40	1.38e-04	188	95	6	3281_UP
Drug	Triamcinolone [124-94-7]; Up 200; 10.2uM; HL60; HG-U133A	ITSN1 YLPM1 PER1 TJAP1 ULK1 TNFAIP3	1.38e-04	188	95	6	1395_UP
Drug	Mianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A	KLHL29 DOCK5 MST1R ATN1 U2SURP CPEB3	1.42e-04	189	95	6	2231_UP
Drug	troglitazone; Down 200; 10uM; HL60; HT_HG-U133A	MYOF SH3BP2 ETV5 TJAP1 BHLHE40 TNS1	1.42e-04	189	95	6	2692_DN
Drug	5253409; Up 200; 17uM; MCF7; HT_HG-U133A_EA	FOXO1 PRR36 YLPM1 ETV5 TNFAIP3 BHLHE40	1.47e-04	190	95	6	961_UP
Drug	Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A	VPS37C MYOF ATN1 SH3BP2 PER1 RERE	1.60e-04	193	95	6	3262_UP
Drug	Clozapine [5786-21-0]; Up 200; 12.2uM; PC3; HT_HG-U133A	TFEB SRRT DLG5 PER1 RERE TNS1	1.60e-04	193	95	6	4670_UP
Drug	Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Down 200; 21uM; MCF7; HT_HG-U133A	DOCK5 MYOF PRR36 BICRA SH3BP2 TNFAIP3	1.64e-04	194	95	6	4159_DN
Drug	Graveoline [485-61-0]; Down 200; 14.4uM; MCF7; HT_HG-U133A	SRRT ITSN1 ETV5 TJAP1 TNS1 CPSF7	1.64e-04	194	95	6	4738_DN
Drug	radicicol; Down 200; 0.1uM; PC3; HT_HG-U133A	DLG5 ARHGEF40 ATN1 SEMA6D RERE TNS1	1.64e-04	194	95	6	5952_DN
Drug	Heptaminol hydrochloride [543-15-7]; Down 200; 22uM; HL60; HT_HG-U133A	DOCK5 TFEB SH3BP2 ITSN1 PER1 MEF2D	1.69e-04	195	95	6	1866_DN
Drug	valinomycin; Down 200; 0.1uM; PC3; HT_HG-U133A	SRRT ITSN1 YLPM1 NUP214 TNFAIP3 TNS1	1.69e-04	195	95	6	5911_DN
Drug	Metrizamide [31112-62-6]; Down 200; 5uM; MCF7; HT_HG-U133A	ATN1 PRR36 SH3BP2 CPEB3 ETV5 TJAP1	1.69e-04	195	95	6	4156_DN
Drug	Lasalocid sodium salt [25999-20-6]; Up 200; 6.6uM; MCF7; HT_HG-U133A	MST1R TBX3 PER1 RERE BHLHE40 TNS1	1.74e-04	196	95	6	3360_UP
Drug	Epirizole [18694-40-1]; Up 200; 17uM; MCF7; HT_HG-U133A	KLHL29 DOCK5 TFEB ATN1 TNS1 UST	1.74e-04	196	95	6	1681_UP
Drug	genistein; Up 200; 10uM; MCF7; HT_HG-U133A	FAM193B POU6F2 ATN1 PRR36 SH3BP2 ETV5	1.74e-04	196	95	6	5232_UP
Drug	Sulfathiazole [72-14-0]; Down 200; 15.6uM; PC3; HT_HG-U133A	MYOF ATN1 PER1 NUP214 ULK1 RERE	1.78e-04	197	95	6	4183_DN
Drug	Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A	TFEB MYOF DLG5 PRR36 PER1 C15orf39	1.78e-04	197	95	6	3862_DN
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A	KLHL29 SRRT MYOF GLI3 YLPM1 NUP214	1.78e-04	197	95	6	6940_UP
Drug	rotenone; Up 200; 1uM; MCF7; HT_HG-U133A	TFEB PDX1 TJAP1 RIMBP2 TNFAIP3 TNS1	1.78e-04	197	95	6	5915_UP
Drug	Merbromin [129-16-8]; Down 200; 5uM; MCF7; HT_HG-U133A	DOCK5 FOXO1 BICRA SH3BP2 C15orf39 TNFAIP3	1.78e-04	197	95	6	3439_DN
Drug	Meticrane [1084-65-7]; Down 200; 14.6uM; MCF7; HT_HG-U133A	PRR36 SH3BP2 ITSN1 YLPM1 TJAP1 TNFAIP3	1.78e-04	197	95	6	1671_DN
Drug	Cyclopentolate hydrochloride [5870-29-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A	TFEB MYOF MXRA5 ATN1 SH3BP2 TNFAIP3	1.78e-04	197	95	6	3555_UP
Drug	Brompheniramine maleate [980-71-2]; Up 200; 9.2uM; MCF7; HT_HG-U133A	ARHGEF40 SH3BP2 PER1 ETV5 BHLHE40 MEF2D	1.78e-04	197	95	6	4131_UP
Drug	Boldine [476-70-0]; Down 200; 12.2uM; HL60; HT_HG-U133A	FOXO1 TFEB BICRA GLI3 SH3BP2 MEF2D	1.78e-04	197	95	6	2148_DN
Drug	Dimethadione [695-53-4]; Down 200; 31uM; MCF7; HT_HG-U133A	KLHL29 FOXO1 MYOF DLG5 SH3BP2 PER1	1.78e-04	197	95	6	5668_DN
Drug	Pirenperone [ 75444-65-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A	SEMA6D SH3BP2 ETV5 TNFAIP3 RERE MEF2D	1.78e-04	197	95	6	5274_UP
Drug	Nadolol [42200-33-9]; Up 200; 13uM; MCF7; HT_HG-U133A	SOX3 MYOF TBX3 ATN1 AUTS2 NUP214	1.83e-04	198	95	6	3359_UP
Drug	Megestrol acetate [595-33-5]; Down 200; 10.4uM; MCF7; HT_HG-U133A	FOXO1 MYOF GLI3 CPEB3 TNFAIP3 UST	1.83e-04	198	95	6	5013_DN
Drug	Sulfachloropyridazine [80-32-0]; Down 200; 14uM; MCF7; HT_HG-U133A	ATN1 SEMA6D PRR36 SH3BP2 ETV5 RERE	1.83e-04	198	95	6	3944_DN
Drug	Tribenoside [10310-32-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A	ARHGEF40 ATN1 SH3BP2 AUTS2 TJAP1 TNS1	1.83e-04	198	95	6	5429_UP
Drug	Sulfabenzamide [127-71-9]; Down 200; 14.4uM; HL60; HT_HG-U133A	FOXO1 TFEB SH3BP2 PER1 ETV5 TNS1	1.83e-04	198	95	6	2159_DN
Drug	Canrenoic acid potassium salt [2181-04-6]; Up 200; 10uM; PC3; HT_HG-U133A	TFEB PRR36 PER1 C15orf39 TNFAIP3 ATG2A	1.83e-04	198	95	6	2065_UP
Drug	Ampicillin trihydrate [7177-48-2]; Up 200; 10uM; HL60; HG-U133A	DOCK5 GLI3 ETV5 TJAP1 KIF5A MEF2D	1.83e-04	198	95	6	2030_UP
Drug	Natamycin [7681-93-8]; Up 200; 6uM; MCF7; HT_HG-U133A	SPTBN4 TFEB MYOF SEMA6D ITSN1 RERE	1.83e-04	198	95	6	3548_UP
Drug	Foliosidine [2520-38-9]; Up 200; 13uM; PC3; HT_HG-U133A	SRRT PRR36 CPEB3 TJAP1 RERE MEF2D	1.83e-04	198	95	6	3739_UP
Drug	Isoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; HL60; HG-U133A	CDH22 ARHGEF40 BICRA ITSN1 TJAP1 RERE	1.83e-04	198	95	6	1985_UP
Drug	nordihydroguaiaretic acid; Down 200; 1uM; HL60; HT_HG-U133A	DOCK5 FOXO1 TFEB MYOF ETV5 TJAP1	1.88e-04	199	95	6	2683_DN
Drug	CP-320650-01 [172079-28-6]; Down 200; 10uM; MCF7; HT_HG-U133A	KLHL29 TFEB SRRT PRR36 SH3BP2 TJAP1	1.94e-04	200	95	6	4379_DN
Drug	ATN-2	ATN1 RERE	2.56e-04	6	95	2	CID003081684
Disease	dentatorubral-pallidoluysian atrophy (implicated_via_orthology)	ATN1 RERE	1.03e-05	2	95	2	DOID:0060162 (implicated_via_orthology)
Disease	fear of minor pain measurement	DOCK5 CRACDL CPEB3	1.36e-04	31	95	3	EFO_0008340
Disease	body surface area	KLHL29 DOCK5 FOXO1 TFEB ARHGEF40 ZBTB4 PER1 AUTS2 CABLES1	2.33e-04	643	95	9	EFO_0022196
Disease	coffee consumption measurement	CUX2 FAM120A SH3BP2 AUTS2 UBE2Q2	3.13e-04	182	95	5	EFO_0006781
Disease	opioid use disorder	POU6F2 SEMA6D CRACDL BARHL2	3.24e-04	101	95	4	EFO_0010702
Disease	Coffin-Siris syndrome (implicated_via_orthology)	SOX11 SMARCC2	3.64e-04	9	95	2	DOID:1925 (implicated_via_orthology)
Disease	smoking cessation	KLHL29 MST1R SEMA6D RBM33 BARHL2 AUTS2	6.51e-04	325	95	6	EFO_0004319
Disease	cognitive function measurement	MST1R POU6F2 KMT2D FAM120A SEMA6D GLI3 BARHL2 PER1 AUTS2 RIMBP2 KMT2E BHLHE40 WNK2	6.81e-04	1434	95	13	EFO_0008354
Disease	Coffin-Siris syndrome	SOX11 SMARCC2	7.82e-04	13	95	2	C0265338
Disease	smoking behavior	POU6F2 SEMA6D BARHL2 AUTS2 RERE CABLES1	8.36e-04	341	95	6	EFO_0004318
Disease	age at last pregnancy measurement	MST1R BARHL2	9.10e-04	14	95	2	EFO_0009440
Disease	unipolar depression, mood disorder	KLHL29 MST1R YLPM1 RERE	9.40e-04	134	95	4	EFO_0003761, EFO_0004247
Disease	platelet crit	KLHL29 FOXO1 CSRNP1 ARHGEF40 U2SURP YLPM1 RERE MEF2D PKN3 CABLES1	9.90e-04	952	95	10	EFO_0007985
Disease	Lymphoma, Large-Cell, Follicular	KMT2D TNFAIP3	1.05e-03	15	95	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	KMT2D TNFAIP3	1.05e-03	15	95	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	KMT2D TNFAIP3	1.05e-03	15	95	2	C0079758
Disease	Lymphoma, Follicular, Grade 2	KMT2D TNFAIP3	1.05e-03	15	95	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	KMT2D TNFAIP3	1.05e-03	15	95	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	KMT2D TNFAIP3	1.05e-03	15	95	2	C1956130
Disease	response to methotrexate	POU6F2 UST	1.20e-03	16	95	2	GO_0031427
Disease	digit length ratio	GLI3 GLIS1	1.20e-03	16	95	2	EFO_0004841
Disease	Abnormality of refraction	POU6F2 GLI3 BARHL2 ZBTB4 AUTS2 RIMBP2 RERE GLIS1	1.50e-03	673	95	8	HP_0000539
Disease	Cannabis use initiation	KLHL29 UST	1.52e-03	18	95	2	EFO_0007586
Disease	noggin measurement	CSRNP1 MEF2D	1.52e-03	18	95	2	EFO_0021995
Disease	cancer (implicated_via_orthology)	TBX3 CUX2 RBL1 KANK4 SMARCC2	1.77e-03	268	95	5	DOID:162 (implicated_via_orthology)
Disease	intellectual disability (implicated_via_orthology)	RBL1 ITSN1 MEF2D	1.85e-03	75	95	3	DOID:1059 (implicated_via_orthology)
Disease	Lymphoma, Follicular	KMT2D TNFAIP3	1.88e-03	20	95	2	C0024301
Disease	dyslexia	POU6F2 FAM120A AUTS2 KMT2E	1.89e-03	162	95	4	EFO_0005424
Disease	chronotype measurement	KLHL29 KMT2D SEMA6D SH3BP2 BARHL2 CPEB3 PER1 AUTS2 RERE	2.17e-03	882	95	9	EFO_0008328
Disease	alcohol drinking	CUX2 AUTS2 KMT2E	2.30e-03	81	95	3	EFO_0004329
Disease	neuroticism measurement, cognitive function measurement	KLHL29 POU6F2 FAM120A SEMA6D YLPM1 AUTS2 RERE	2.38e-03	566	95	7	EFO_0007660, EFO_0008354
Disease	response to selective serotonin reuptake inhibitor	SEMA6D BICRA AUTS2	2.38e-03	82	95	3	EFO_0005658
Disease	alcoholic liver disease	DLG5 CUX2 GLI3	2.38e-03	82	95	3	EFO_0008573
Disease	depressive symptom measurement	KLHL29 POU6F2 FAM120A SEMA6D YLPM1 RERE	2.58e-03	426	95	6	EFO_0007006
Disease	cortical thickness	KLHL29 SOX11 ARHGEF40 GLI3 YLPM1 AUTS2 RERE MBD6 TNS1 WNK2	3.11e-03	1113	95	10	EFO_0004840

Protein segments in the cluster

Peptide	Gene	Start	Entry
PSLHDSSPPPLSGQP	NT5C1B	161	Q96P26
NQLSGASPPHPPTTP	ERICH6B	6	Q5W0A0
PSLQPPHPGSSTPTL	ARHGEF40	1481	Q8TER5
AAIVPPPSVQGHPFP	CXorf49;	106	A8MYA2
LISSPFLGPHPHQPP	BHLHE40	306	O14503
PSAPPPANFPHVTPN	ATN1	286	P54259
SFHLSPRGPPTSEPP	SH3BP2	336	P78314
APTFPPHPVVFLPGT	GUSBP11	206	Q6P575
DLLPGSPFHVALPPP	DPH2	386	Q9BQC3
ILPPGHSHPDPTPQS	CUX2	1246	O14529
PLPSHLDLPSFAPPA	ATG2A	1001	Q2TAZ0
PGSPASTQPPPLHFS	POLN	881	Q7Z5Q5
HPVPTQSPLPFTQPG	RBM33	496	Q96EV2
PPGAIPPALHLNPAF	CPSF7	281	Q8N684
PPALHLNPAFFPPPN	CPSF7	286	Q8N684
GQSTPSPHLVPSPAP	PTPN23	1076	Q9H3S7
LPSQTPGHSLTPPPS	PUM2	626	Q8TB72
PNSSLLGHPFPPSVP	PATL1	241	Q86TB9
VLPPGTSHFTPPQTP	CASKIN1	766	Q8WXD9
DAHLPPPPTLSSGSP	MBD6	436	Q96DN6
IHPAPTFPTQRPIPG	GLI3	381	P10071
NIEAPHFPLPGLSPP	CSRNP1	531	Q96S65
LAPSPPHRPDSPLFN	PER1	961	O15534
LPAQLALPHPPAGPF	PDX1	86	P52945
PPPLPLTGAHRFSAP	PLXNB3	36	Q9ULL4
PPPNSSSSVHPGPLA	AUTS2	1006	Q8WXX7
LLPGPGPAHSPQPSK	DLG5	991	Q8TDM6
GPPLFPSSAHPTVPP	KMT2E	1746	Q8IZD2
SGPLSHPTPLSAPPS	NUP214	621	P35658
APLPLPSPTSPGFQF	EP400P1	81	Q6ZTU2
PPPQATLPTSGHAPA	ETV5	151	P41161
QSHTLPFPPPPALPF	FAM120A	851	Q9NZB2
PLLQSFTLPHQPAPP	CRACDL	766	Q6NV74
PAQHFGPRLPSPDPT	PATL2	121	C9JE40
QGHPLPKSFSSPPSP	C6orf132	956	Q5T0Z8
VPPPASQHSTPAGLP	FBF1	376	Q8TES7
LSQHPPVPPAAAGPL	FOXO1	131	Q12778
PFHGSSPPQSTPLSP	DOCK5	1776	Q9H7D0
PQPSSLPPLIPGGHA	CABLES1	141	Q8TDN4
PLLPGLSFHQPPQQP	CPEB3	76	Q8NE35
LIPSHPSSFGSPPHP	FAM193B	261	Q96PV7
PSSFGSPPHPHLLPT	FAM193B	266	Q96PV7
GAPPVIQPLPAFAHP	ITSN1	161	Q15811
PLPPASNPPGTVHSA	BCL9L	891	Q86UU0
PSPTPLGSNIPLHPN	BCL9L	1176	Q86UU0
PALNPLSSPIPGTPH	BARHL2	371	Q9NY43
PVRPGHYPASSPTNP	KIF5A	921	Q12840
VPNHLPLPGPPFSFQ	KANK4	241	Q5T7N3
LPSERHSLPQGPPSP	CDH22	726	Q9UJ99
HSPGGQPFPTLPSKP	GLIS1	481	Q8NBF1
PGPSSSPSLPHQAPL	BICRA	771	Q9NZM4
APGASTQPPPHLPTK	BICRA	1231	Q9NZM4
SPPPPTHSTQLGAPS	MEF2D	251	Q14814
HRPPGPLFSSSDPLP	nan	821	A6NNC1
EFTGLPPALTPPAPH	PKN3	851	Q6P5Z2
PPNPHLIIPTPEGFS	MAP3K4	1161	Q9Y6R4
QHPPPLAQPALSPAS	SOX11	321	P35716
PHPRPAPQSKPLASS	RIMBP2	591	O15034
PAPGAPSPPATLAHL	SOX3	56	P41225
AHISPAQGSPKPPPA	TFEB	106	P19484
HPPTLPPSAPLQFLT	RNF38	331	Q9H0F5
HQPPFFPALTLPPNG	TBX3	36	O15119
PRTLNGVSSPPHPSP	PPP1R12C	391	Q9BZL4
GLPPSHSSPSLQPKP	PSD	986	A5PKW4
PPLSPFPHIKQQPGS	RBL1	961	P28749
HSGSPTYLQLPPRPP	PLEKHA4	326	Q9H4M7
GPSHPAQPKAPRFPS	PROSER2	241	Q86WR7
VNPPLPTTFQPGAPH	SEC24A	196	O95486
HPPFPVGPQPLLTAQ	POU6F2	86	P78424
SPPQKPSQSPGHGLP	POU6F2	271	P78424
GHGLPSPLTPPNPLQ	POU6F2	281	P78424
HLLQAPFSPPPSPPV	PRR36	881	Q9H6K5
VFPPSPQPHGPLASS	SPATA31E1	241	Q6ZUB1
SPTPPKLSPGQLSPH	DIP2C-AS1	171	Q8N8Z3
PPTGLHQVAPQPPFA	RERE	1021	Q9P2R6
HHLPFAPGTLPPPNL	SMARCC2	1121	Q8TAQ2
QASPPHPCRFLLGPP	SLX4	1026	Q8IY92
LTPGLPYPHQTPQGL	SRRT	781	Q9BXP5
EHTLPPPPSGLPFNA	U2SURP	371	O15042
SPQAHSYPGPPLAAP	C15orf39	116	Q6ZRI6
PHHQPSPAPLTLSAP	TJAP1	386	Q5JTD0
HGPPPSKVLPFPSQV	UST	91	Q9Y2C2
PQQGSPHSLPPPLTL	UBE2Q2	41	Q8WVN8
PSPSLSPSPLHGIFQ	PHF21B	216	Q96EK2
GPHSAPPTAPSPFLF	TNFAIP3	456	P21580
NLSPAPHLASGSPPP	SRCIN1	296	Q9C0H9
AFLPTTHSPPGPQQP	TNS1	821	Q9HBL0
GVSTPSPPHPQASPK	ZNF395	226	Q9H8N7
GPPPSVITFAHPAPS	ZBTB4	466	Q9P1Z0
PPPPPTHTVQHEGFL	SPTBN4	2411	Q9H254
PPTTYHPPLQSAGPS	YLPM1	681	P49750
QGLPSPPGTPHSPSY	ZDHHC8	671	Q9ULC8
APEPSPHSGTPQPAL	WNK2	1516	Q9Y3S1
PLPPNVGFFHTAPPT	WNK2	1966	Q9Y3S1
SPAQPASPHPVGLAP	XKR5	576	Q6UX68
PQFFPSSPPPHSPLS	SEMA6D	806	Q8NFY4
PYSPSPSLPVGPTAH	VPS37C	206	A5D8V6
SIAFPLANPPVAPHP	TOPBP1	1236	Q92547
HFQSKLITPPPPPPS	PRR11	26	Q96HE9
AVLPPTLPQPASHFP	PRR11	171	Q96HE9
GFRFLPPPHPPSANL	MST1R	856	Q04912
VFSPPQASPPQPSHG	ULK1	581	O75385
PGHYSLPQPPSQPLS	KLHL29	201	Q96CT2
PGTPRHQPSTPDPFL	KMT2D	2231	O14686
DFGPPAPPLLHTPQT	MXRA5	1781	Q9NR99
PPSAPHPNDLSGPSV	MYOF	126	Q9NZM1