Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	frizzled binding	WNT2 WNT9A LRP6	3.45e-04	42	65	3	GO:0005109
GeneOntologyMolecularFunction	extracellular matrix structural constituent	FBN2 LAMA5 EMILIN3 LTBP2 EDIL3	3.67e-04	188	65	5	GO:0005201
GeneOntologyMolecularFunction	beta-tubulin binding	RANBP10 HDAC6 PACRG	5.45e-04	49	65	3	GO:0048487
GeneOntologyMolecularFunction	extracellular matrix constituent conferring elasticity	FBN2 EMILIN3	6.74e-04	12	65	2	GO:0030023
GeneOntologyCellularComponent	extracellular matrix	ADAMTSL1 FCGBP FBN2 PHOSPHO1 SFTPB WNT2 CSPG4 LAMA5 EMILIN3 LTBP2 ADAMTS13 EDIL3	7.25e-07	656	65	12	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ADAMTSL1 FCGBP FBN2 PHOSPHO1 SFTPB WNT2 CSPG4 LAMA5 EMILIN3 LTBP2 ADAMTS13 EDIL3	7.49e-07	658	65	12	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	ADAMTSL1 FBN2 SFTPB WNT2 CSPG4 LAMA5 EMILIN3 LTBP2 EDIL3	3.66e-05	530	65	9	GO:0062023
Domain	EGF	FCGBP FBN2 LAMA5 LRP6 LTBP2 EDIL3	1.52e-04	235	64	6	SM00181
Domain	CLTH	RANBP10 RANBP9	1.72e-04	6	64	2	PF10607
Domain	CRA	RANBP10 RANBP9	1.72e-04	6	64	2	SM00757
Domain	CTLH/CRA	RANBP10 RANBP9	1.72e-04	6	64	2	IPR024964
Domain	CRA_dom	RANBP10 RANBP9	1.72e-04	6	64	2	IPR013144
Domain	EGF-like_dom	FCGBP FBN2 LAMA5 LRP6 LTBP2 EDIL3	2.08e-04	249	64	6	IPR000742
Domain	TB	FBN2 LTBP2	2.40e-04	7	64	2	PF00683
Domain	-	FBN2 LTBP2	3.19e-04	8	64	2	3.90.290.10
Domain	CTLH	RANBP10 RANBP9	4.10e-04	9	64	2	SM00668
Domain	TB	FBN2 LTBP2	4.10e-04	9	64	2	PS51364
Domain	TB_dom	FBN2 LTBP2	4.10e-04	9	64	2	IPR017878
Domain	LisH	RANBP10 RANBP9	4.10e-04	9	64	2	PF08513
Domain	CTLH_C	RANBP10 RANBP9	5.11e-04	10	64	2	IPR006595
Domain	CTLH	RANBP10 RANBP9	5.11e-04	10	64	2	PS50897
Domain	EGF_1	FBN2 LAMA5 LRP6 LTBP2 EDIL3	1.80e-03	255	64	5	PS00022
Domain	Wnt	WNT2 WNT9A	1.90e-03	19	64	2	IPR005817
Domain	Wnt_CS	WNT2 WNT9A	1.90e-03	19	64	2	IPR018161
Domain	wnt	WNT2 WNT9A	1.90e-03	19	64	2	PF00110
Domain	WNT1	WNT2 WNT9A	1.90e-03	19	64	2	SM00097
Domain	WNT1	WNT2 WNT9A	1.90e-03	19	64	2	PS00246
Domain	EGF-like_CS	FBN2 LAMA5 LRP6 LTBP2 EDIL3	2.00e-03	261	64	5	IPR013032
Domain	EGF_2	FBN2 LAMA5 LRP6 LTBP2 EDIL3	2.13e-03	265	64	5	PS01186
Domain	F-box_dom	FBXW10B FBXW10 BTRC	2.17e-03	75	64	3	IPR001810
Domain	WD40_repeat_CS	FBXW10B FBXW10 LYST BTRC	2.42e-03	164	64	4	IPR019775
Domain	Peptidase_M12B_ADAM-TS	ADAMTSL1 ADAMTS13	3.04e-03	24	64	2	IPR013273
Domain	G-protein_beta_WD-40_rep	FBXW10B FBXW10 BTRC	3.10e-03	85	64	3	IPR020472
Domain	LisH	RANBP10 RANBP9	4.13e-03	28	64	2	SM00667
Domain	hEGF	FBN2 EDIL3	4.13e-03	28	64	2	PF12661
Domain	LisH	RANBP10 RANBP9	4.13e-03	28	64	2	IPR006594
Domain	LISH	RANBP10 RANBP9	4.13e-03	28	64	2	PS50896
Domain	EGF_Ca-bd_CS	FBN2 LTBP2 EDIL3	4.50e-03	97	64	3	IPR018097
Domain	EGF_CA	FBN2 LTBP2 EDIL3	4.76e-03	99	64	3	PS01187
Domain	ASX_HYDROXYL	FBN2 LTBP2 EDIL3	4.90e-03	100	64	3	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBN2 LTBP2 EDIL3	5.76e-03	106	64	3	IPR000152
Domain	ConA-like_dom	RANBP10 CSPG4 RANBP9 LAMA5	6.75e-03	219	64	4	IPR013320
Domain	LAM_G_DOMAIN	CSPG4 LAMA5	7.51e-03	38	64	2	PS50025
Domain	-	TRIM32 LRP6	7.89e-03	39	64	2	2.120.10.30
Domain	Laminin_G_2	CSPG4 LAMA5	8.29e-03	40	64	2	PF02210
Domain	EGF_CA	FBN2 LTBP2 EDIL3	8.48e-03	122	64	3	SM00179
Domain	EGF_3	FBN2 LRP6 LTBP2 EDIL3	8.61e-03	235	64	4	PS50026
Domain	EGF-like_Ca-bd_dom	FBN2 LTBP2 EDIL3	8.86e-03	124	64	3	IPR001881
Pathway	REACTOME_SIGNALING_BY_MET	PTPN1 RANBP10 RANBP9 LAMA5	2.34e-04	79	54	4	M27643
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBN2 EMILIN3 LTBP2	2.44e-04	32	54	3	MM14854
Pathway	WNT_SIGNALING	WNT2 WNT9A LRP6 BTRC	3.69e-04	89	54	4	M5493
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBN2 EMILIN3 LTBP2	3.76e-04	37	54	3	M27134
Pathway	KEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY	WNT2 WNT9A LRP6	3.76e-04	37	54	3	M47411
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBN2 EMILIN3 LTBP2	4.40e-04	39	54	3	MM14601
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBN2 EMILIN3 LTBP2	6.30e-04	44	54	3	M26969
Pathway	REACTOME_MET_ACTIVATES_RAS_SIGNALING	RANBP10 RANBP9	6.35e-04	10	54	2	MM15488
Pathway	KEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY	WNT2 WNT9A LRP6	6.73e-04	45	54	3	M47412
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY	WNT2 WNT9A LRP6	7.18e-04	46	54	3	M47409
Pathway	REACTOME_MET_ACTIVATES_RAS_SIGNALING	RANBP10 RANBP9	7.75e-04	11	54	2	M27740
Pubmed	Deficiency of PTP1B in POMC neurons leads to alterations in energy balance and homeostatic response to cold exposure.	PTPN1 POMC	3.55e-06	2	66	2	21406615
Pubmed	Role of PTP1B in POMC neurons during chronic high-fat diet: sex differences in regulation of liver lipids and glucose tolerance.	PTPN1 POMC	3.55e-06	2	66	2	29351427
Pubmed	FBXW10 promotes hepatocarcinogenesis in male patients and mice.	FBXW10B FBXW10	3.55e-06	2	66	2	31400758
Pubmed	Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.	FBXW10B FBXW10	3.55e-06	2	66	2	37450367
Pubmed	Aggresome formation is regulated by RanBPM through an interaction with HDAC6.	HDAC6 RANBP9	3.55e-06	2	66	2	24795145
Pubmed	Activation of beta-Catenin in mouse prostate causes HGPIN and continuous prostate growth after castration.	WNT2 WNT9A BTRC	9.80e-06	22	66	3	18991257
Pubmed	Inhibition of HDAC6 activity through interaction with RanBPM and its associated CTLH complex.	HDAC6 RANBP9	1.06e-05	3	66	2	28668087
Pubmed	PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice.	PTPN1 POMC	1.06e-05	3	66	2	20160350
Pubmed	The relationship between HDAC6, CXCR3, and SIRT1 genes expression levels with progression of primary open-angle glaucoma.	CXCR3 HDAC6	1.06e-05	3	66	2	29384425
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	ADAMTSL1 SFTPB CSPG4 LAMA5 LTBP2	1.70e-05	167	66	5	22159717
Pubmed	Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes.	WNT2 WNT9A EDIL3	2.07e-05	28	66	3	20940229
Pubmed	Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPM.	RANBP10 RANBP9	2.12e-05	4	66	2	12147692
Pubmed	Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development.	WNT2 WNT9A EDIL3	2.55e-05	30	66	3	36305473
Pubmed	Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.	WNT2 WNT9A LRP6 BTRC	2.67e-05	90	66	4	19515997
Pubmed	FBXW10-S6K1 promotes ANXA2 polyubiquitination and KRAS activation to drive hepatocellular carcinoma development in males.	FBXW10B FBXW10	3.53e-05	5	66	2	37277019
Pubmed	Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus.	WNT9A BTRC	3.53e-05	5	66	2	19047045
Pubmed	Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.	FBN2 WNT2 LAMA5	4.84e-05	37	66	3	34323105
Pubmed	Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles.	TRIM32 EDIL3	5.29e-05	6	66	2	26418459
Pubmed	Wnt/β-catenin pathway is regulated by PITX2 homeodomain protein and thus contributes to the proliferation of human ovarian adenocarcinoma cell, SKOV-3.	WNT2 WNT9A	5.29e-05	6	66	2	23250740
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	GTPBP2 TRIM32 RANBP9 EMILIN3 NOL9 EIF6	6.75e-05	364	66	6	24778252
Pubmed	DNA sequence and analysis of human chromosome 9.	ADAMTSL1 FAM201A TRIM32 PLPP7 ADAMTS13 TEX10	7.39e-05	370	66	6	15164053
Pubmed	Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination.	WNT2 WNT9A POMC	9.97e-05	47	66	3	16678101
Pubmed	Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.	WNT2 WNT9A LRP6	1.13e-04	49	66	3	19562671
Pubmed	Sox9 plays multiple roles in the lung epithelium during branching morphogenesis.	SFTPB LAMA5 LRP6	1.20e-04	50	66	3	24191021
Pubmed	LAS1L interacts with the mammalian Rix1 complex to regulate ribosome biogenesis.	NOL9 TEX10	1.27e-04	9	66	2	22190735
Pubmed	Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.	FBN2 WNT2 CSPG4	1.35e-04	52	66	3	30389913
Pubmed	Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung Development and Prenatal Lethality.	FBN2 SFTPB TACSTD2	1.43e-04	53	66	3	33153107
Pubmed	Functional consequences of cell type-restricted expression of laminin α5 in mouse placental labyrinth and kidney glomerular capillaries.	LAMA5 EDIL3	1.58e-04	10	66	2	22911783
Pubmed	Expression patterns of Wnt genes during development of an anterior part of the chicken eye.	WNT2 WNT9A	1.58e-04	10	66	2	16258938
Pubmed	HDAC6 interacts with PTPN1 to enhance melanoma cells progression.	PTPN1 HDAC6	1.58e-04	10	66	2	29278704
Pubmed	YPEL5 protein of the YPEL gene family is involved in the cell cycle progression by interacting with two distinct proteins RanBPM and RanBP10.	RANBP10 RANBP9	1.58e-04	10	66	2	20580816
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	CSPG4 LAMA5 LTBP2 EDIL3	1.75e-04	146	66	4	27068509
Pubmed	Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis.	SFTPB WNT2	1.93e-04	11	66	2	9006067
Pubmed	Defective lymphatic valve development and chylothorax in mice with a lymphatic-specific deletion of Connexin43.	GJA4 LAMA5	1.93e-04	11	66	2	27899284
Pubmed	Gene trap screening as an effective approach for identification of Wnt-responsive genes in the mouse embryo.	WNT2 WNT9A	2.31e-04	12	66	2	15778975
Pubmed	Epithelial Wnt/β-catenin signaling regulates palatal shelf fusion through regulation of Tgfβ3 expression.	WNT2 LRP6	2.31e-04	12	66	2	21185284
Pubmed	Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex.	LRP6 BTRC	2.31e-04	12	66	2	22682247
Pubmed	Kelch-like ECT2-interacting protein KLEIP regulates late-stage pulmonary maturation via Hif-2α in mice.	SFTPB CSPG4	2.73e-04	13	66	2	24785085
Pubmed	Smooth muscle-endothelial cell communication activates Reelin signaling and regulates lymphatic vessel formation.	CSPG4 LAMA5	3.18e-04	14	66	2	22665518
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	ADAMTSL1 FBN2 LAMA5 LTBP2	3.50e-04	175	66	4	28071719
Pubmed	Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina.	CSPG4 EDIL3	3.67e-04	15	66	2	26630461
Pubmed	MOR is not enough: identification of novel mu-opioid receptor interacting proteins using traditional and modified membrane yeast two-hybrid screens.	GJA4 RANBP9	3.67e-04	15	66	2	23840749
Pubmed	USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating β-Catenin Deubiquitination.	TRIM32 BTRC	4.18e-04	16	66	2	29045831
Pubmed	The COP9 signalosome mediates beta-catenin degradation by deneddylation and blocks adenomatous polyposis coli destruction via USP15.	LRP6 BTRC	4.18e-04	16	66	2	19576224
Pubmed	Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice.	GJA4 LAMA5	4.18e-04	16	66	2	26953188
Pubmed	Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development.	GJA4 CSPG4	4.18e-04	16	66	2	26542011
Pubmed	Laminin α1 is essential for mouse cerebellar development.	LAMA5 EDIL3	4.74e-04	17	66	2	21983115
Pubmed	Identification of RanBP 9/10 as interacting partners for protein kinase C (PKC) gamma/delta and the D1 dopamine receptor: regulation of PKC-mediated receptor phosphorylation.	RANBP10 RANBP9	4.74e-04	17	66	2	20395553
Pubmed	Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax.	GJA4 CSPG4	4.74e-04	17	66	2	21515254
Pubmed	Wnt family proteins are secreted and associated with the cell surface.	WNT2 WNT9A	4.74e-04	17	66	2	8167409
Pubmed	Mesenchymal Wnt signaling promotes formation of sternum and thoracic body wall.	WNT2 LRP6	4.74e-04	17	66	2	25727890
Pubmed	Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation.	NOL9 TEX10	4.74e-04	17	66	2	22872859
Pubmed	Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation.	GJA4 LAMA5	4.74e-04	17	66	2	22306086
Pubmed	Pituitary hypoplasia and respiratory distress syndrome in Prop1 knockout mice.	SFTPB POMC	4.74e-04	17	66	2	15459176
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	PTPN1 RANBP10 MRPL47 NLRC5 NOL9 TEX10	5.26e-04	533	66	6	30554943
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	RANBP10 XPNPEP3 RANBP9 NOL9 TEX10 EIF6	5.26e-04	533	66	6	25544563
Pubmed	Deletion of STK40 protein in mice causes respiratory failure and death at birth.	SFTPB WNT2	5.32e-04	18	66	2	23293024
Pubmed	GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126.	GJA4 LAMA5	5.32e-04	18	66	2	31582413
Pubmed	A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.	CSPG4 LAMA5	5.32e-04	18	66	2	14730302
Pubmed	ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.	FBN2 LAMA5	5.32e-04	18	66	2	39040056
Pubmed	Murine inner cell mass-derived lineages depend on Sall4 function.	SALL3 EDIL3	5.32e-04	18	66	2	17060609
Pubmed	Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.	SALL3 PHOSPHO1 LAMA5 GPR143	5.90e-04	201	66	4	23535732
Pubmed	Meis2 Is Required for Inner Ear Formation and Proper Morphogenesis of the Cochlea.	MYO7B EDIL3	5.94e-04	19	66	2	34124068
Pubmed	Coronary Artery Formation Is Driven by Localized Expression of R-spondin3.	WNT2 WNT9A	5.94e-04	19	66	2	28834739
Pubmed	Loss of the centrosomal protein Cenpj leads to dysfunction of the hypothalamus and obesity in mice.	HDAC6 POMC	5.94e-04	19	66	2	32803714
Pubmed	Prenatal lung epithelial cell-specific abrogation of Alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation.	SFTPB LRP6	5.94e-04	19	66	2	18258849
Pubmed	The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation.	WNT2 EDIL3	5.94e-04	19	66	2	21822279
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	FBN2 LTBP2 EDIL3	5.97e-04	86	66	3	28327460
Pubmed	A genomic atlas of mouse hypothalamic development.	WNT9A POMC ZFTA LHX8	6.35e-04	205	66	4	20436479
Pubmed	Transcriptome analysis of human gastric cancer.	FCGBP ARSA KRTCAP3 NAA38 TACSTD2 EIF6 KIFC2	6.46e-04	772	66	7	16341674
Pubmed	A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration.	SFTPB WNT2	6.59e-04	20	66	2	18536717
Pubmed	SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions.	NOL9 TEX10	7.28e-04	21	66	2	37014752
Pubmed	The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium.	WNT2 WNT9A	7.28e-04	21	66	2	11914369
Pubmed	Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.	RNF187 BTRC	7.28e-04	21	66	2	37005481
Pubmed	Schwann cell myelination requires integration of laminin activities.	LAMA5 EDIL3	7.28e-04	21	66	2	22767514
Pubmed	Epithelial Wnt10a Is Essential for Tooth Root Furcation Morphogenesis.	WNT2 WNT9A	7.28e-04	21	66	2	31914354
Pubmed	Cardiac outflow tract development relies on the complex function of Sox4 and Sox11 in multiple cell types.	CSPG4 EDIL3	7.99e-04	22	66	2	24310815
Pubmed	Expression of the Wnt inhibitor Dickkopf-1 is required for the induction of neural markers in mouse embryonic stem cells differentiating in response to retinoic acid.	WNT2 LRP6	7.99e-04	22	66	2	17064353
Pubmed	High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.	PHOSPHO1 WNT9A POMC LRP6 LTBP2	8.13e-04	383	66	5	19453261
Pubmed	Does murine spermatogenesis require WNT signalling? A lesson from Gpr177 conditional knockout mouse models.	WNT2 WNT9A	8.75e-04	23	66	2	27362799
Pubmed	Characterization and in vivo pharmacological rescue of a Wnt2-Gata6 pathway required for cardiac inflow tract development.	SALL3 WNT2	8.75e-04	23	66	2	20159597
Pubmed	HuR controls lung branching morphogenesis and mesenchymal FGF networks.	WNT2 EDIL3	8.75e-04	23	66	2	21515253
Pubmed	Lymphatic function is required prenatally for lung inflation at birth.	SFTPB CSPG4	9.53e-04	24	66	2	24733830
Pubmed	Loss of semaphorin-neuropilin-1 signaling causes dysmorphic vascularization reminiscent of alveolar capillary dysplasia.	SFTPB CSPG4	9.53e-04	24	66	2	23063659
Pubmed	Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm.	SFTPB WNT2	1.03e-03	25	66	2	15186480
Pubmed	Submandibular parasympathetic gangliogenesis requires sprouty-dependent Wnt signals from epithelial progenitors.	WNT2 WNT9A	1.03e-03	25	66	2	25805134
Pubmed	Endocardial to myocardial notch-wnt-bmp axis regulates early heart valve development.	WNT2 WNT9A	1.03e-03	25	66	2	23560082
Pubmed	Epithelial cell integrin β1 is required for developmental angiogenesis in the pituitary gland.	CSPG4 POMC	1.12e-03	26	66	2	27810956
Pubmed	Adamts18 modulates the development of the aortic arch and common carotid artery.	FBN2 LAMA5	1.12e-03	26	66	2	34189436
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RANBP10 CSPG4 NLRC5 LAMA5 LRRC14 LYST EIF6 KIFC2	1.14e-03	1105	66	8	35748872
Pubmed	Activation of the Wnt-beta catenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections.	WNT2 WNT9A	1.21e-03	27	66	2	17804636
Pubmed	Deterministic and stochastic allele specific gene expression in single mouse blastomeres.	HDAC6 ACADM WNT2 LRP6 KIFC2	1.28e-03	424	66	5	21731673
Pubmed	Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development.	WNT2 WNT9A	1.30e-03	28	66	2	24394376
Pubmed	Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme.	WNT2 EDIL3	1.30e-03	28	66	2	18367557
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	MRPL47 LAMA5 NOL9 TEX10	1.34e-03	251	66	4	28077445
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	RANBP10 RANBP9 NOL9 TEX10	1.38e-03	253	66	4	29911972
Pubmed	Wnt5a potentiates TGF-β signaling to promote colonic crypt regeneration after tissue injury.	WNT2 WNT9A	1.39e-03	29	66	2	22956684
Pubmed	3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19).	WNT2 WNT9A	1.39e-03	29	66	2	18364260
Pubmed	Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature.	LRP6 EDIL3	1.39e-03	29	66	2	19023080
Pubmed	Genetic interactions of the androgen and Wnt/beta-catenin pathways for the masculinization of external genitalia.	WNT2 WNT9A	1.49e-03	30	66	2	19282366
Interaction	PRG3 interactions	RANBP10 FBN2 RANBP9 LRP6	1.65e-05	49	63	4	int:PRG3
Interaction	FBN1 interactions	ZDHHC15 FBN2 RANBP9 LAMA5	1.94e-05	51	63	4	int:FBN1
Interaction	FBXW10B interactions	FBXW10B FBXW10	2.88e-05	3	63	2	int:FBXW10B
Interaction	FBN2 interactions	ZDHHC15 ADAMTSL1 FBN2 LTBP2	5.09e-05	65	63	4	int:FBN2
Interaction	LECT2 interactions	RANBP10 CSPG4 RANBP9	5.62e-05	24	63	3	int:LECT2
Cytoband	Xq13.3	ZDHHC15 UPRT	3.80e-04	20	66	2	Xq13.3
Cytoband	20q12	EMILIN3 EIF6	5.50e-04	24	66	2	20q12
Cytoband	Ensembl 112 genes in cytogenetic band chrXq13	ZDHHC15 CXCR3 UPRT	1.77e-03	165	66	3	chrXq13
Cytoband	17p12	FBXW10B FBXW10	2.29e-03	49	66	2	17p12
Cytoband	Ensembl 112 genes in cytogenetic band chr9p22	TTC39B ADAMTSL1	2.68e-03	53	66	2	chr9p22
Cytoband	Ensembl 112 genes in cytogenetic band chr11q13	MRGPRF PGM2L1 ZFTA SPINDOC	4.20e-03	454	66	4	chr11q13
Cytoband	2p23.3	KRTCAP3 POMC	4.36e-03	68	66	2	2p23.3
GeneFamily	WD repeat domain containing\|F-box and WD repeat domain containing	FBXW10B FBXW10 BTRC	2.19e-06	11	44	3	559
GeneFamily	SUMO specific peptidases\|5FMC ribosome biogenesis complex	NOL9 TEX10	8.63e-05	6	44	2	1301
GeneFamily	Wnt family\|Endogenous ligands	WNT2 WNT9A	9.64e-04	19	44	2	360
GeneFamily	WD repeat domain containing	FBXW10B FBXW10 LYST BTRC	3.71e-03	262	44	4	362
ToppCell	Parenchymal-10x5prime-Stromal-Myofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GJA4 SLC7A2 MRGPRF CSPG4 LTBP2 EDIL3	5.06e-07	199	66	6	20f760d92c351a1dac4cc0a424c443ea03a179fe
ToppCell	COVID-19-kidney-vSMC/Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GJA4 SLC7A2 ADAMTSL1 CSPG4 EDIL3	6.92e-06	179	66	5	111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell	normal_Lung-Fibroblasts-Pericytes\|normal_Lung / Location, Cell class and cell subclass	GJA4 MRGPRF CSPG4 LTBP2 EDIL3	7.30e-06	181	66	5	f74941e49950027360d71ea3b205fc20c6929766
ToppCell	Control-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	PTPN1 SH3TC2 SLC7A2 LTBP2 LYST	9.24e-06	190	66	5	4e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	GJA4 MRGPRF CSPG4 LTBP2 EDIL3	9.97e-06	193	66	5	9104b572d9c3c99080e4b7455993fbb944bf117d
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 ADAMTSL1 MRGPRF CSPG4 LAMA5	1.02e-05	194	66	5	bf34737ae2dc218f890fbb9201c308b324415749
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 MRGPRF CSPG4 EDIL3	1.02e-05	194	66	5	5099e6ad7c19e5f8b73449d904aaefd97f1b1959
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 MRGPRF CSPG4 EDIL3	1.02e-05	194	66	5	71734ef7b34ab33b349595368176fa0e1175d4d0
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 ADAMTSL1 MRGPRF CSPG4 LAMA5	1.02e-05	194	66	5	4ebed7a6731b88c8359860072cbeba355a7e90ac
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 MRGPRF CSPG4 EDIL3	1.05e-05	195	66	5	e10b21e4dba4483efc4c82d6e395524246ca14a8
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 MRGPRF CSPG4 EDIL3	1.05e-05	195	66	5	9ab3c5b0fb12d406408122a535b717bfe184bbcf
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 MRGPRF CSPG4 EDIL3	1.05e-05	195	66	5	21263d138c81f6a0219f2cd93126cfafd35732b2
ToppCell	356C-Fibroblasts-Fibroblast-K_(Pericytes)\|356C / Donor, Lineage, Cell class and subclass (all cells)	GJA4 MRGPRF CSPG4 LTBP2 EDIL3	1.07e-05	196	66	5	a5cc4f76e1a3825aaccba9a686d7da6f7e4300ff
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-K_(Pericytes)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	GJA4 SLC7A2 CSPG4 LAMA5 EDIL3	1.07e-05	196	66	5	541b1fcf509e362f6f48720046cb5378aaf7c591
ToppCell	367C-Fibroblasts-Fibroblast-K_(Pericytes)\|367C / Donor, Lineage, Cell class and subclass (all cells)	GJA4 SLC7A2 MRGPRF CSPG4 EDIL3	1.07e-05	196	66	5	c390ef0adff35111989a30dff86b7c5db1a89873
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 MRGPRF CSPG4 EDIL3	1.07e-05	196	66	5	5146976881d79642ebe5dcbcf89e0252713a9ef2
ToppCell	367C-Fibroblasts-Fibroblast-K_(Pericytes)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	GJA4 SLC7A2 MRGPRF CSPG4 EDIL3	1.07e-05	196	66	5	2f76f050083483f0880639e6c34ff349caac3503
ToppCell	356C-Fibroblasts-Fibroblast-K_(Pericytes)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	GJA4 MRGPRF CSPG4 LTBP2 EDIL3	1.07e-05	196	66	5	476812fc1422aca8010d771eff11fa6081f15a2d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 MRGPRF CSPG4 EDIL3	1.07e-05	196	66	5	ebac1d6af7a5732707d82d01285c086b19d8ae62
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 MRGPRF CSPG4 EDIL3	1.10e-05	197	66	5	d14e1f2ba94240c61eac435db43508a224d606a8
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GJA4 MRGPRF CSPG4 LTBP2 EDIL3	1.10e-05	197	66	5	01249bd485a3734de87ae6ed9c749597f39c6335
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 MRGPRF CSPG4 EDIL3	1.13e-05	198	66	5	54c8aa47040bc4977eed382514fc4ceae03f54f8
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 MRGPRF CSPG4 EDIL3	1.13e-05	198	66	5	daf367b699726286f0f0f7b4f3a6cf70c462fbeb
ToppCell	cellseq-Mesenchymal-Myocytic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GJA4 MRGPRF CSPG4 LTBP2 EDIL3	1.16e-05	199	66	5	20e62a7029fa0d214244cdf2a481fc5d78290438
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GJA4 SLC7A2 MRGPRF CSPG4 EDIL3	1.16e-05	199	66	5	ad75e5e26c37a97331164d7f77235ebd9a933a44
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TCAF1 MRGPRF GPR143 LTBP2 ADAMTS13	1.16e-05	199	66	5	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	Parenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GJA4 MRGPRF CSPG4 LTBP2 EDIL3	1.16e-05	199	66	5	7c272a1aa7f3e931ad5d20809719d85b3bce4cb0
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC7A2 FBN2 CSPG4 LTBP2 EDIL3	1.18e-05	200	66	5	be527df943a8cedc6452ecef3cafc282db34ceb8
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	GJA4 FBN2 MRGPRF CSPG4 EDIL3	1.18e-05	200	66	5	b5b5a32925f225610fe25a021a742d6397162863
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	GJA4 FBN2 MRGPRF CSPG4 EDIL3	1.18e-05	200	66	5	4e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	GJA4 MRGPRF CSPG4 LRP6 EDIL3	1.18e-05	200	66	5	cf883ba5dbe6350b93142d625a52b25ff2a8bb63
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC7A2 FBN2 CSPG4 LTBP2 EDIL3	1.18e-05	200	66	5	8e41a484038216f0c2ad258fd46c0e702a4bb8bf
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TCAF1 MRGPRF GPR143 LTBP2 ADAMTS13	1.18e-05	200	66	5	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte\|LPS_only / Treatment groups by lineage, cell group, cell type	GJA4 FBN2 MRGPRF CSPG4 EDIL3	1.18e-05	200	66	5	8c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	TCAF1 MRGPRF GPR143 LTBP2 ADAMTS13	1.18e-05	200	66	5	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A2 FBN2 CSPG4 LTBP2 EDIL3	1.18e-05	200	66	5	c935caef2988f165e96d8f1ef99ae8963ab9377f
ToppCell	facs-Skin-Anagen-24m-Epithelial-inner_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3TC2 CXCR3 ZFTA SPINDOC	1.49e-05	100	66	4	97ca9cda55a05fbb4d1f5d61f847c965e014f05c
ToppCell	TCGA-Skin\|World / Sample_Type by Project: Shred V9	SH3TC2 CSPG4 GPR143 LYST	5.57e-05	140	66	4	57d9979bfdcb695869690bf62fa80759ad06eb6c
ToppCell	COVID-19_Severe-dn_T\|COVID-19_Severe / Disease condition and Cell class	PGM2L1 TACSTD2 LYST S1PR4	5.89e-05	142	66	4	2008033881b9e1b20926c3508d6ebdb6f1a1528f
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chodl\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	WNT2 KRTCAP3 GPR143 LHX8	6.22e-05	144	66	4	b622b605f7ec6083ec06c8ea0fd171e07c52f3de
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC7A2 MRGPRF CSPG4 POMC	7.67e-05	152	66	4	bd1f36b436d8ab7dd8420f595b97d851eab31a38
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC7A2 MRGPRF CSPG4 POMC	7.67e-05	152	66	4	ee329249a034a969a16b26a224aa04249d67382d
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GJA4 SH3TC2 PHOSPHO1 SFTPB	7.86e-05	153	66	4	65641cc82883716dba0fefb749a30174a63f4da5
ToppCell	droplet-Liver-Npc-21m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CXCR3 FCGBP FBN2 TACSTD2	8.27e-05	155	66	4	d883a3869cf893d62741f26f641ed3923aba03f9
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SH3TC2 LAMA5 ADAMTS13 EDIL3	8.69e-05	157	66	4	1e3a4a7193d95f09d71c2dfe704b8e626c6d9624
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 CSPG4 EDIL3	9.81e-05	162	66	4	c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 CSPG4 EDIL3	9.81e-05	162	66	4	f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 CSPG4 EDIL3	9.81e-05	162	66	4	5d902bb31e691aea9749617cc88303c2448f24b8
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZDHHC15 CXCR3 NLRC5 S1PR4	1.03e-04	164	66	4	1a9b444d2c6abcc83d4355ec5228b27541df2bd0
ToppCell	BAL-Mild-cDC_11\|Mild / Compartment, Disease Groups and Clusters	CXCR3 SFTPB TACSTD2 SLC26A1	1.03e-04	164	66	4	4bd9629d054545d1e3f9e5c127b5ac2388637106
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC7A2 PHOSPHO1 CSPG4 EMILIN3	1.05e-04	165	66	4	9de841c1c95967c562720feba930246debc626fd
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC7A2 PHOSPHO1 CSPG4 EMILIN3	1.05e-04	165	66	4	a612a7d3a5415ecacc3df8fbff0ce498f982aad0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC7A2 PHOSPHO1 CSPG4 EMILIN3	1.05e-04	165	66	4	cdc94a640ec01c6892521bcd6f0ee0a66ff23866
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WNT2 POMC LHX8 SLC26A1	1.08e-04	166	66	4	aa2df07eff323ded751ced8938af08223d7f2029
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WNT2 POMC LHX8 SLC26A1	1.08e-04	166	66	4	695298a94d62b8adab083900003ec636fbaae5d9
ToppCell	facs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RANBP10 SH3TC2 SLC26A1 KIFC2	1.13e-04	168	66	4	17fb9426eeea407b26fb895b8397faca95b7552d
ToppCell	facs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RANBP10 SH3TC2 SLC26A1 KIFC2	1.13e-04	168	66	4	a61b39884851384cffd430079040546d125b2b40
ToppCell	control-dn_T\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CXCR3 NLRC5 PGM2L1 S1PR4	1.18e-04	170	66	4	839f62860b4a52d06e6a8fce7632195c7310b89d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_endothelial_cell_-_unspecif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CSRNP1 GJA4 POMC ZFTA	1.29e-04	174	66	4	66a3b20ff1ab9f36fb391986444d7dc99d0c03d1
ToppCell	metastatic_Brain-Myeloid_cells-CD141+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	CXCR3 MYO7B NLRC5 TACSTD2	1.29e-04	174	66	4	5ec8a48a390379d6c422120dce46437a77da67cc
ToppCell	5'-Adult-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 SLC7A2 MRGPRF CSPG4	1.32e-04	175	66	4	294a70786260c9a2b1ba16c88819d786698609e7
ToppCell	droplet-Liver-Npc-21m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CXCR3 FCGBP FBN2 TACSTD2	1.32e-04	175	66	4	046e841811b22c39f80a9752f3223c1906de6f20
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 CSPG4 EDIL3	1.32e-04	175	66	4	316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell	5'-Adult-LymphNode-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 SLC7A2 MRGPRF CSPG4	1.32e-04	175	66	4	798f33bd340261c048b7b45c842b2ccd1ea1fb60
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 CSPG4 EDIL3	1.32e-04	175	66	4	a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell	3'-Adult-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 CSPG4 LAMA5 PLPP7	1.35e-04	176	66	4	56e19240f4a7b617a986e3c0854b757394e78251
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 SLC7A2 CSPG4 LAMA5	1.35e-04	176	66	4	90f36f10c6ed440a0ca549f23219398853f1fbc3
ToppCell	AT1_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	CSRNP1 WNT9A LAMA5 TACSTD2	1.35e-04	176	66	4	4a30bb771297b30926fb98e2b5ec0dbdc46feac7
ToppCell	3'-Adult-LymphNode-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 CSPG4 LAMA5 PLPP7	1.35e-04	176	66	4	c88b46fe29ae7606c8880a6ff0ebb85c0dfda8bd
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_A2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	KRTCAP3 LAMA5 PACRG RFNG	1.35e-04	176	66	4	052b54c4337ca728974a106b6dbd3b72dd28eb23
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GJA4 CSPG4 LTBP2 EDIL3	1.41e-04	178	66	4	185b44700f06ec58b3c09c80520502166c965fd6
ToppCell	facs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 ADAMTSL1 CSPG4 LAMA5	1.44e-04	179	66	4	8da6863edc756540bb097cc7221c1408640d9bb4
ToppCell	facs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 ADAMTSL1 CSPG4 LAMA5	1.44e-04	179	66	4	f39c13c99a07d009cc677e363ffe089089c64916
ToppCell	droplet-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSRNP1 GJA4 SFTPB S1PR4	1.44e-04	179	66	4	006f2b6887b0f1f26e58bb11c919468b62bf4d62
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A2 FCGBP KRTCAP3 TACSTD2	1.50e-04	181	66	4	3fd16229a63de0971db5d48860c01173d7db518f
ToppCell	control-Treg\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CXCR3 TRIM32 PGM2L1 S1PR4	1.54e-04	182	66	4	8e96a9dd70814cb0925776613b3a12026d455cad
ToppCell	Pericytes-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	GJA4 ADAMTSL1 MRGPRF CSPG4	1.54e-04	182	66	4	46c213597445b1f4f09dc367f27702d24b201daf
ToppCell	Pericytes-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	GJA4 MRGPRF CSPG4 EDIL3	1.60e-04	184	66	4	cd10d351d91a81dd6dc806cb4e0c8d7861c98e0b
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CSRNP1 GJA4 ZDHHC15 MYO7B	1.60e-04	184	66	4	16ed515fb673a9d6973133afcda0a3fba4a8d9dc
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 CSPG4 EDIL3	1.63e-04	185	66	4	7092436b4db90289516ed130ade596e3021cffaf
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FBN2 CSPG4 EMILIN3 EDIL3	1.63e-04	185	66	4	8ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 CSPG4 EDIL3	1.63e-04	185	66	4	51dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 MRGPRF LHX8 TACSTD2	1.63e-04	185	66	4	5f5df92b328be396941b5812d00454b5ff927d30
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 CSPG4 EDIL3	1.63e-04	185	66	4	a8ca7819066d5297ef6966e7f3e2c9f8a7673fdc
ToppCell	droplet-Lung-21m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA4 CXCR3 SFTPB S1PR4	1.63e-04	185	66	4	9c907298166e3dd65b1d1e7673a1b8d01b492bd0
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 MRGPRF LHX8 TACSTD2	1.63e-04	185	66	4	98547c1b1828b76da810ed86082182afaaacdb3f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 SLC7A2 CSPG4 EDIL3	1.63e-04	185	66	4	a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCell	droplet-Lung-nan-21m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 CXCR3 SFTPB S1PR4	1.63e-04	185	66	4	43b7345a61e31099718c9cecf194b4e9884b904b
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FCGBP KRTCAP3 LAMA5 TACSTD2	1.67e-04	186	66	4	37b93ebd64ebbd08193a746e5bc9b350c2570733
ToppCell	droplet-Fat-Scat-21m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A2 FCGBP KRTCAP3 TACSTD2	1.67e-04	186	66	4	59710cff3f6f7c318ee2524b44c1a909f312c25e
ToppCell	droplet-Fat-Scat-21m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A2 FCGBP KRTCAP3 TACSTD2	1.67e-04	186	66	4	de88fafac51049ec1920695844d8ce8057940272
ToppCell	droplet-Fat-Scat-21m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A2 FCGBP KRTCAP3 TACSTD2	1.67e-04	186	66	4	7ff73ab8fed5da779ee9c7bd2e14a8363edb7509
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GJA4 SLC7A2 CSPG4 EDIL3	1.70e-04	187	66	4	fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FCGBP KRTCAP3 LAMA5 TACSTD2	1.74e-04	188	66	4	8ffb5394f7b00ea483a5fe4df894d22fda935e5c
ToppCell	normal_Lung-Fibroblasts-Smooth_muscle_cells\|normal_Lung / Location, Cell class and cell subclass	GJA4 MRGPRF LTBP2 EDIL3	1.74e-04	188	66	4	fd70fb89570f014d1299c60fe017dc09f24e57c6
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-chondrocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MRGPRF CSPG4 EMILIN3 EDIL3	1.74e-04	188	66	4	5a89587ee6f2b4dc14244bd88bb31efb81c50dbe
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FCGBP KRTCAP3 LAMA5 TACSTD2	1.74e-04	188	66	4	137ed9958044fab7a13648affb469585d1c48cf6
ToppCell	5'-Adult-Appendix-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 SLC7A2 MRGPRF CSPG4	1.77e-04	189	66	4	0daa8efac08dca9525d2b8d421952068cab4eb50
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSRNP1 FCGBP NLRC5 TACSTD2	1.77e-04	189	66	4	1cfc1fe27c4b57b4e52700fa8f679ce172cee5a9
ToppCell	5'-Adult-Appendix-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 SLC7A2 MRGPRF CSPG4	1.77e-04	189	66	4	b6bb4327b4560d07d2b728abcc5f144f428948a5
Disease	Nephrocalcinosis	POMC SLC26A1	1.39e-05	3	64	2	C0027709
Disease	nonanoylcarnitine (C9) measurement	ACADM LHX8	6.91e-05	6	64	2	EFO_0800381
Disease	octanoylcarnitine measurement	ACADM LHX8	1.65e-04	9	64	2	EFO_0021042
Disease	hexanoylcarnitine measurement	ACADM LHX8	3.01e-04	12	64	2	EFO_0021040
Disease	obstructive sleep apnea	CAMKMT LHX8 PACRG	4.04e-04	66	64	3	EFO_0003918
Disease	glutamine measurement	CSRNP1 SLC7A2 PGM2L1	1.24e-03	97	64	3	EFO_0009768
Disease	Weight Gain	ACADM POMC RFNG	1.43e-03	102	64	3	C0043094
Disease	Bright Disease	CXCR3 POMC	2.07e-03	31	64	2	C1704377
Disease	cholesteryl esters to total lipids in large LDL percentage	TTC39B NLRC5	2.07e-03	31	64	2	EFO_0022249
Disease	Glomerulonephritis	CXCR3 POMC	2.07e-03	31	64	2	C0017658

Protein segments in the cluster

Peptide	Gene	Start	Entry
MDLGALARNCGRESR	CXCR3	281	P49682
GLREALLTRNMAAGC	CSPG4	366	Q6UVK1
MDSRVSELFGGCCRP	GTPBP2	1	Q9BX10
MDLCKNRLVSGGRDC	FBXW10	501	Q5XX13
GCSSLADSMPSLRCL	BTRC	26	Q9Y297
MAAGFGRCCRVLRSI	ACADM	1	P11310
CRCLSTMDLIALGVG	SLC7A2	31	P52569
AGSCSVSCGRGLMEL	ADAMTS13	901	Q76LX8
QCLGLMARSGIGSCA	RANBP9	706	Q96S59
SECLRLMARAGLGSC	RANBP10	596	Q6VN20
RLECSGAIMARCNLD	PACRG	211	Q96M98
MSRARGALCRACLAL	RFNG	1	Q9Y644
MDLCKNRLVSGGRDC	FBXW10B	501	O95170
MADSGLLLKRGSCRS	NOL9	1	Q5SY16
MGLRAGSRCRADHLA	FAM201A	1	Q5SY85
RSGTFCLADTCLLLM	PTPN1	221	P18031
RGGCTLGMALRHSAC	CSRNP1	106	Q96S65
MECCRRATPGTLLLF	ADAMTSL1	1	Q8N6G6
LCCRMTFGTAGLRSA	PGM2L1	61	Q6PCE3
MPRSCCSRSGALLLA	POMC	1	P01189
MGAVLRSLLACSFCV	LRP6	1	O75581
RCQGLMSEECGRTTA	LHX8	6	Q68G74
TMRMSRGGCSGLLRC	ARSA	286	P15289
MAKRLCAGSALCVRG	LAMA5	1	O15230
CRRLEELMLGCNALG	NLRC5	1661	Q86WI3
ASIAGCRIIGRMCVG	EIF6	51	P56537
TLRMELLGCELSGCS	EDIL3	306	O43854
CMGGGDRDILCKALA	FCGBP	3111	Q9Y6R7
ACDLLGCLGMVIRST	GPR143	76	P51810
TRAICGLSRNFCLLM	LYST	3501	Q99698
RGSYLCTCRPGLMLD	LTBP2	641	Q14767
RMTDGRTLVGCFLCT	NAA38	56	Q9BRA0
RGSCCGQLALINARM	EMILIN3	381	Q9NT22
LLCRCLSRGMRARQG	GJA4	231	P35212
MCRLEELGLAGRCLT	HDAC6	511	Q9UBN7
SRCIDQRTGMCFSGL	FBN2	356	P35556
CLRLGMRGPGDCLAR	S1PR4	326	O95977
VCALCRRGCSTMGNL	SALL3	1006	Q9BXA9
LRARMASLRQGCGDL	KIFC2	336	Q96AC6
MRRCSLCAFDAARGP	KRTCAP3	1	Q53RY4
LSEAVGLLMCRSCGR	TRIM32	91	Q13049
RCIAGMCVDARGDLI	TRIM32	576	Q13049
CRLVLRCSMDDSAGP	SFTPB	271	P07988
LCRADAGPLCAACRM	RNF187	96	Q5TA31
DCCRGAMLSLATGLA	TCAF1	486	Q9Y4C2
RSVCRVLGLCMFLTG	MRGPRF	116	Q96AM1
GRCQCRALGSGMAVD	TACSTD2	51	P09758
MLSGARCRLASALRG	PYURF	1	Q96I23
MGGCFCIPRERSLTR	SH3TC2	1	Q8TF17
SGRALCMVCGAEIRA	SPINDOC	86	Q9BUA3
MAAAGLALLCRRVSS	MRPL47	1	Q9HD33
RALAVCELGGGMTCL	CAMKMT	146	Q7Z624
GRVCNLTSRGMDSCE	WNT2	291	P09544
EGASGRSMRSALCCL	TTC39B	341	Q5VTQ0
MAGVRSLRCSRGCAG	MIS18A	1	Q9NYP9
TLNGSAAMLDCGRDC	SLC26A1	161	Q9H2B4
MSGCFPVSGLRCLSR	PHOSPHO1	1	Q8TCT1
LSRCCIMGRLSSSLA	TEX10	636	Q9NXF1
CSECGERSPMSARLA	ZNF786	371	Q8N393
ALAKACSAGRMERCT	WNT9A	136	O14904
NVRGLSGCMLCSQRR	XPNPEP3	16	Q9NQH7
RSGEAMEQGLRDCCR	UPRT	186	Q96BW1
SRRGLVCMVCGGALA	ZFTA	596	C9JLR9
CMSKRLGVCAGRAAS	PLPP7	91	Q8NBV4
KMALSGGLRCCRRVL	ZDHHC15	6	Q96MV8
GRFTCLRELSMGSSL	LRRC14	281	Q15048
MALGSLGRGSRLLCE	MYO7B	2066	Q6PIF6