Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionO-acyltransferase activity

ACAT1 AGPAT1 AGPAT2 CPT2 LPGAT1 GNPAT

4.88e-06591486GO:0008374
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO5A MYO5B KIF26B MYO1H DNAH6 KLC1 DNAH11

2.83e-051181487GO:0003774
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

ACAT1 AGPAT1 AGPAT2 CPT2 LPGAT1 HADHB PHF10 EP300 GNPAT

7.27e-052381489GO:0016747
GeneOntologyMolecularFunctionacyltransferase activity

RGPD2 RANBP2 ACAT1 AGPAT1 AGPAT2 MARCHF7 CPT2 TGM1 LPGAT1 UBR3 HADHB HERC1 PHF10 EP300 BTRC GNPAT

2.10e-0477514816GO:0016746
GeneOntologyMolecularFunctionglutaminase activity

GLS2 GLS

3.24e-0441482GO:0004359
GeneOntologyMolecularFunction1-acylglycerol-3-phosphate O-acyltransferase activity

AGPAT1 AGPAT2 LPGAT1

4.81e-04211483GO:0003841
GeneOntologyMolecularFunctionATP-dependent activity

MYO5A MYO5B KIF26B ZGRF1 MYO1H CCT2 BPTF SMARCA2 DHX35 DNAH6 ABCG8 PIF1 DNAH11

6.65e-0461414813GO:0140657
GeneOntologyMolecularFunctionlysophosphatidic acid acyltransferase activity

AGPAT1 AGPAT2 LPGAT1

7.20e-04241483GO:0042171
GeneOntologyMolecularFunctionlysophospholipid acyltransferase activity

AGPAT1 AGPAT2 LPGAT1

7.20e-04241483GO:0071617
GeneOntologyMolecularFunctiontelomerase inhibitor activity

TEN1 PIF1

8.03e-0461482GO:0010521
GeneOntologyMolecularFunctionacetyl-CoA C-acetyltransferase activity

ACAT1 HADHB

8.03e-0461482GO:0003985
GeneOntologyMolecularFunctionalkali metal ion binding

ACAT1 CPS1 SCN8A

9.15e-04261483GO:0031420
GeneOntologyMolecularFunctionacetyltransferase activity

ACAT1 HADHB PHF10 EP300 GNPAT

1.07e-031041485GO:0016407
GeneOntologyMolecularFunctionC-acetyltransferase activity

ACAT1 HADHB

1.12e-0371482GO:0016453
GeneOntologyMolecularFunctionacetyl-CoA C-acyltransferase activity

ACAT1 HADHB

1.12e-0371482GO:0003988
GeneOntologyCellularComponentfatty acid beta-oxidation multienzyme complex

ACACB HADHB

1.59e-0431532GO:0036125
GeneOntologyCellularComponentmitochondrial fatty acid beta-oxidation multienzyme complex

ACACB HADHB

1.59e-0431532GO:0016507
DomainAcyltransferase

AGPAT1 AGPAT2 LPGAT1 GNPAT

6.40e-06161484PF01553
DomainPlsC

AGPAT1 AGPAT2 LPGAT1 GNPAT

8.32e-06171484SM00563
DomainPlipid/glycerol_acylTrfase

AGPAT1 AGPAT2 LPGAT1 GNPAT

8.32e-06171484IPR002123
DomainGlutaminase

GLS2 GLS

6.24e-0521482IPR015868
DomainDDI1_N

DDI2 DDI1

6.24e-0521482IPR033882
DomainAGP_acyltrans

AGPAT1 AGPAT2

6.24e-0521482IPR004552
DomainGlutaminase

GLS2 GLS

6.24e-0521482PF04960
Domain-

GLS2 GLS

1.86e-04314823.40.710.10
DomainBeta-lactam/transpept-like

GLS2 GLS

1.86e-0431482IPR012338
DomainAsp_protease

DDI2 DDI1

6.14e-0451482PF09668
DomainPeptidase_aspartic_DDI1-type

DDI2 DDI1

6.14e-0451482IPR019103
DomainMyosin_S1_N

MYO5A MYO5B

6.14e-0451482IPR008989
DomainThiolase_AS

ACAT1 HADHB

6.14e-0451482IPR020610
DomainThiolase_acyl_enz_int_AS

ACAT1 HADHB

6.14e-0451482IPR020615
DomainCPSASE_1

ACACB CPS1

6.14e-0451482PS00866
DomainThiolase_C

ACAT1 HADHB

9.16e-0461482PF02803
DomainDilute_dom

MYO5A MYO5B

9.16e-0461482IPR002710
DomainTHIOLASE_2

ACAT1 HADHB

9.16e-0461482PS00737
DomainTHIOLASE_1

ACAT1 HADHB

9.16e-0461482PS00098
DomainTHIOLASE_3

ACAT1 HADHB

9.16e-0461482PS00099
DomainThiolase_N

ACAT1 HADHB

9.16e-0461482IPR020616
DomainThiolase_C

ACAT1 HADHB

9.16e-0461482IPR020617
DomainThiolase_CS

ACAT1 HADHB

9.16e-0461482IPR020613
DomainThiolase

ACAT1 HADHB

9.16e-0461482IPR002155
DomainDIL

MYO5A MYO5B

9.16e-0461482PF01843
DomainThiolase_N

ACAT1 HADHB

9.16e-0461482PF00108
DomainCPSASE_2

ACACB CPS1

9.16e-0461482PS00867
DomainDILUTE

MYO5A MYO5B

9.16e-0461482PS51126
DomainDIL

MYO5A MYO5B

9.16e-0461482SM01132
DomainBromodomain_CS

BPTF SMARCA2 EP300

1.11e-03261483IPR018359
DomainCbamoylP_synth_lsu-like_ATP-bd

ACACB CPS1

1.28e-0371482IPR005479
DomainBC-like_N

ACACB CPS1

1.28e-0371482IPR005481
DomainCPSase_L_D2

ACACB CPS1

1.28e-0371482PF02786
DomainBiotin_carb_N

ACACB CPS1

1.28e-0371482PF00289
DomainARM-like

MROH2A RICTOR WDFY4 MROH2B ZER1 RIC8A CFAP69 STAG2

1.42e-032701488IPR011989
DomainARM-type_fold

MROH2A INTS1 RICTOR WDFY4 MROH2B ZER1 RIC8A CFAP69 STAG2

1.55e-033391489IPR016024
DomainPH_dom-like

RGPD2 RANBP2 WDFY4 OPHN1 JAK3 CADPS RALGPS1 TLN1 MTMR3 OSBPL11

2.14e-0342614810IPR011993
DomainGPS

ADGRV1 ADGRG4 CELSR2

2.44e-03341483SM00303
DomainGPS

ADGRV1 ADGRG4 CELSR2

2.65e-03351483PF01825
Domain-

ACAT1 HADHB

2.69e-031014823.40.47.10
DomainThiolase-like

ACAT1 HADHB

2.69e-03101482IPR016039
DomainGPS

ADGRV1 ADGRG4 CELSR2

2.87e-03361483PS50221
DomainGPS

ADGRV1 ADGRG4 CELSR2

3.11e-03371483IPR000203
DomainBROMODOMAIN_1

BPTF SMARCA2 EP300

3.11e-03371483PS00633
DomainBromodomain

BPTF SMARCA2 EP300

3.36e-03381483PF00439
DomainGPCR_2_extracellular_dom

ADGRV1 ADGRG4 CELSR2

3.89e-03401483IPR001879
DomainG_PROTEIN_RECEP_F2_1

ADGRV1 ADGRG4 CELSR2

3.89e-03401483PS00649
DomainG_PROTEIN_RECEP_F2_3

ADGRV1 ADGRG4 CELSR2

3.89e-03401483PS50227
DomainRan_BP1

RGPD2 RANBP2

3.91e-03121482PF00638
DomainRANBD1

RGPD2 RANBP2

3.91e-03121482PS50196
Domain-

DDI2 DDI1

3.91e-031214822.40.70.10
DomainBROMODOMAIN_2

BPTF SMARCA2 EP300

4.17e-03411483PS50014
DomainBromodomain

BPTF SMARCA2 EP300

4.46e-03421483IPR001487
DomainBROMO

BPTF SMARCA2 EP300

4.46e-03421483SM00297
Domain-

BPTF SMARCA2 EP300

4.46e-034214831.20.920.10
DomainRanBD

RGPD2 RANBP2

4.59e-03131482SM00160
DomainRan_bind_dom

RGPD2 RANBP2

4.59e-03131482IPR000156
Domain-

ACACB CPS1

4.59e-031314823.40.50.20
DomainNHL

TENM2 PAM

4.59e-03131482PS51125
DomainRho_GTPase_activation_prot

STARD8 SRGAP2 PLXND1 OPHN1

5.28e-03881484IPR008936
DomainDynein_heavy_chain_D4_dom

DNAH6 DNAH11

5.33e-03141482IPR024317
DomainDynein_HC_stalk

DNAH6 DNAH11

5.33e-03141482IPR024743
DomainDynein_heavy_dom-2

DNAH6 DNAH11

5.33e-03141482IPR013602
DomainDHC_N2

DNAH6 DNAH11

5.33e-03141482PF08393
DomainATPase_dyneun-rel_AAA

DNAH6 DNAH11

5.33e-03141482IPR011704
DomainGROEL-like_equatorial

CCT2 BBS10

5.33e-03141482IPR027413
DomainATP_GRASP

ACACB CPS1

5.33e-03141482PS50975
DomainATP-grasp

ACACB CPS1

5.33e-03141482IPR011761
DomainPreATP-grasp_dom

ACACB CPS1

5.33e-03141482IPR016185
DomainMT

DNAH6 DNAH11

5.33e-03141482PF12777
DomainAAA_8

DNAH6 DNAH11

5.33e-03141482PF12780
Domain-

CCT2 BBS10

5.33e-031414821.10.560.10
DomainAAA_5

DNAH6 DNAH11

5.33e-03141482PF07728
DomainDHC_fam

DNAH6 DNAH11

6.12e-03151482IPR026983
DomainGroEL-like_apical_dom

CCT2 BBS10

6.12e-03151482IPR027409
DomainDynein_heavy

DNAH6 DNAH11

6.12e-03151482PF03028
DomainCpn60/TCP-1

CCT2 BBS10

6.12e-03151482IPR002423
DomainCpn60_TCP1

CCT2 BBS10

6.12e-03151482PF00118
Domain-

CCT2 BBS10

6.12e-031514823.50.7.10
DomainDynein_heavy_dom

DNAH6 DNAH11

6.12e-03151482IPR004273
Domain-

ACACB CPS1

6.12e-031514823.30.1490.20
Domain7tm_2

ADGRV1 ADGRG4 CELSR2

7.28e-03501483PF00002
DomainG_PROTEIN_RECEP_F2_2

ADGRV1 ADGRG4 CELSR2

7.28e-03501483PS00650
DomainAnk_2

ANKFY1 GLS2 NFKBID GLS PLA2G6 ANKRD24

7.40e-032151486PF12796
DomainPeptidase_aspartic_dom

DDI2 DDI1

7.85e-03171482IPR021109
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

CHMP6 MRPS12 KSR2 AGPAT2 INTS1 SRGAP2 PLXND1 ITPR3 JAK3 JUN TDRD3 POMGNT2 CELSR2 RALGPS1 TLN1 SCN8A MTMR3 ZER1 PLA2G6 RIC8A HERC1 EP300

4.14e-0911051542235748872
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

GABRB1 RGPD2 RANBP2 SLC4A8 ACACB MYO5A ACAT1 PPFIA2 RICTOR TENM2 EEF1G POMGNT2 CELSR2 CADPS GLS UBR3 SPARCL1 HADHB HNRNPLL BTRC

1.71e-0711391542036417873
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

STARD8 SLC4A8 MYO5B RICTOR WDFY4 WAC SAMD9L GLS LPGAT1 UBR3 ANKRD24 GRIN3A ZNF160

3.40e-074931541315368895
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RPGRIP1 RGPD2 RANBP2 MACC1 GLS2 ACACB MYO5A MYO5B CENPF SYNE1 PPFIA2 ECD CCT2 CAGE1 BPTF GLS HADHB DTHD1 CFAP69 DNAH6 STAG2

1.70e-0614421542135575683
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

RGPD2 RANBP2 CENPF SYNE1 ECD CCT2 CPS1 TUBGCP6 STK3 NBAS TGM1 TLN1 SMARCA2 DHX35 HADHB TEN1 PHF10 STAG2

3.96e-0611551541820360068
Pubmed

A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.

KIF26B MROH2A CCDC141 BPTF UBR3 GRIN3A DTHD1 DNAH6

3.97e-06205154812040188
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

CCDC14 CENPF SYNE1 PPFIA2 SRGAP2 WAC SPARCL1

5.27e-06151154717043677
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

CCDC14 KIF26B INTS1 CCT2 SRGAP2 EEF1G USP42 GLS RIC8A HIGD2B MAML2 HADHB DNAH11

1.32e-056891541336543142
Pubmed

Defining the membrane proteome of NK cells.

RANBP2 CHMP6 MYO5A AGPAT1 INTS1 ITPR3 TUBGCP6 NBAS EEF1G BST2 LPGAT1 PAM HNRNPLL STAG2 CNN2 KLC1 GNPAT

1.80e-0511681541719946888
Pubmed

Molecular cloning, sequencing and expression studies of the human breast cancer cell glutaminase.

GLS2 GLS

1.95e-052154210620514
Pubmed

The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.

GLS2 GLS

1.95e-052154228526749
Pubmed

Increased plasma glutamate by antipsychotic medication and its relationship to glutaminase 1 and 2 genotypes in schizophrenia -- Juntendo University Schizophrenia Projects (JUSP).

GLS2 GLS

1.95e-052154217669570
Pubmed

Both GLS silencing and GLS2 overexpression synergize with oxidative stress against proliferation of glioma cells.

GLS2 GLS

1.95e-052154224276018
Pubmed

Full-length human glutaminase in complex with an allosteric inhibitor.

GLS2 GLS

1.95e-052154222049910
Pubmed

Vpu directs the degradation of the human immunodeficiency virus restriction factor BST-2/Tetherin via a {beta}TrCP-dependent mechanism.

BST2 BTRC

1.95e-052154219515779
Pubmed

Characterization of a human lysophosphatidic acid acyltransferase that is encoded by a gene located in the class III region of the human major histocompatibility complex.

AGPAT1 AGPAT2

1.95e-05215429461603
Pubmed

Glutaminase isoforms expression switches microRNA levels and oxidative status in glioblastoma cells.

GLS2 GLS

1.95e-052154233610185
Pubmed

Identification of two human glutaminase loci and tissue-specific expression of the two related genes.

GLS2 GLS

1.95e-052154211130979
Pubmed

Intronic polymorphisms in genes LRFN2 (rs2494938) and DNAH11 (rs2285947) are prognostic indicators of esophageal squamous cell carcinoma.

LRFN2 DNAH11

1.95e-052154231053115
Pubmed

A specific lysine in c-Jun is required for transcriptional repression by E1A and is acetylated by p300.

JUN EP300

1.95e-052154211689449
Pubmed

The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy.

JUN GLS

1.95e-052154227089238
Pubmed

Cloning and expression of two human lysophosphatidic acid acyltransferase cDNAs that enhance cytokine-induced signaling responses in cells.

AGPAT1 AGPAT2

1.95e-05215429212163
Pubmed

Expression of Gls and Gls2 glutaminase isoforms in astrocytes.

GLS2 GLS

1.95e-052154225297978
Pubmed

Genetic variants of DNAH11 and LRFN2 genes and their association with ovarian and breast cancer.

LRFN2 DNAH11

1.95e-052154231605628
Pubmed

Structure and function of the ESCRT-II-III interface in multivesicular body biogenesis.

CHMP6 VPS25

1.95e-052154219686684
Pubmed

Human 1-acylglycerol-3-phosphate O-acyltransferase isoforms 1 and 2: biochemical characterization and inability to rescue hepatic steatosis in Agpat2(-/-) gene lipodystrophic mice.

AGPAT1 AGPAT2

1.95e-052154221873652
Pubmed

Suppression of Tetherin-restricting activity upon human immunodeficiency virus type 1 particle release correlates with localization of Vpu in the trans-Golgi network.

BST2 BTRC

1.95e-052154219244337
Pubmed

A human cDNA sequence with homology to non-mammalian lysophosphatidic acid acyltransferases.

AGPAT1 AGPAT2

1.95e-05215429291118
Pubmed

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells.

GLS2 GLS

1.95e-052154222225880
Pubmed

The variable loop 3 in the envelope glycoprotein is critical for the atypical coreceptor usage of an HIV-1 strain.

GPR15 CCR5

1.95e-052154224897520
Pubmed

Co-expression of glutaminase K and L isoenzymes in human tumour cells.

GLS2 GLS

1.95e-052154215496140
Pubmed

Identifying chemicals with potential therapy of HIV based on protein-protein and protein-chemical interaction network.

JUN CCR5 EP300

2.99e-0514154323762317
Pubmed

Proteomic discovery of Max as a novel interacting partner of C/EBPalpha: a Myc/Max/Mad link.

RPGRIP1 JUN GRIN3A

2.99e-0514154317082780
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

BPTF JUN SMARCA2 STAG2 EP300

3.51e-0583154528794006
Pubmed

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.

ACAT1 CPS1 CPT2 SMARCA2 CCR5 HADHB EP300

3.58e-05203154716916647
Pubmed

Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit.

JUN SMARCA2 EP300

3.73e-0515154314701856
Pubmed

ΔNp63α Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas.

MRPS12 DPH6 RALGPS1 ZFAND6 RIC8A EP300

4.26e-05142154630232004
Pubmed

Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.

SRGAP2 CPS1 STK3 TGM1 CELF2 HADHB KLC1 GNPAT

5.08e-05292154812819125
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

RANBP2 CHMP6 MYO5A MYO5B ACAT1 CENPF SYNE1 INTS1 CCT2 ITPR3 BPTF EEF1G TLN1 HADHB STAG2

5.35e-0510241541524711643
Pubmed

HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation.

BST2 BTRC

5.83e-053154219730691
Pubmed

Quantitative proteomics reveals neuronal ubiquitination of Rngo/Ddi1 and several proteasomal subunits by Ube3a, accounting for the complexity of Angelman syndrome.

DDI2 DDI1

5.83e-053154229788202
Pubmed

Vpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endo-lysosomal trafficking.

BST2 BTRC

5.83e-053154219478868
Pubmed

Human Rab small GTPase- and class V myosin-mediated membrane tethering in a chemically defined reconstitution system.

MYO5A MYO5B

5.83e-053154228939769
Pubmed

In Silico Preliminary Association of Ammonia Metabolism Genes GLS, CPS1, and GLUL with Risk of Alzheimer's Disease, Major Depressive Disorder, and Type 2 Diabetes.

CPS1 GLS

5.83e-053154229441491
Pubmed

The Vpu protein: new concepts in virus release and CD4 down-modulation.

BST2 BTRC

5.83e-053154220201792
Pubmed

βTrCP is Required for HIV-1 Vpu Modulation of CD4, GaLV Env, and BST-2/Tetherin.

BST2 BTRC

5.83e-053154230347660
Pubmed

TCR stimulation upregulates MS4a4B expression through induction of AP-1 transcription factor during T cell activation.

MS4A4A JUN

5.83e-053154222595231
Pubmed

Role for myosin-V motor proteins in the selective delivery of Kv channel isoforms to the membrane surface of cardiac myocytes.

MYO5A MYO5B

5.83e-053154224508725
Pubmed

β-TrCP is dispensable for Vpu's ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 release.

BST2 BTRC

5.83e-053154221310048
Pubmed

Structural insights into the globular tails of the human type v myosins Myo5a, Myo5b, And Myo5c.

MYO5A MYO5B

5.83e-053154224339992
Pubmed

Human CHMP6, a myristoylated ESCRT-III protein, interacts directly with an ESCRT-II component EAP20 and regulates endosomal cargo sorting.

CHMP6 VPS25

5.83e-053154215511219
Pubmed

DNA polymerase ι is acetylated in response to SN2 alkylating agents.

EP300 REV1

5.83e-053154230886224
Pubmed

Retinoids and carnosol suppress cyclooxygenase-2 transcription by CREB-binding protein/p300-dependent and -independent mechanisms.

JUN EP300

5.83e-053154211980644
Pubmed

HDAC4 degradation during senescence unleashes an epigenetic program driven by AP-1/p300 at selected enhancers and super-enhancers.

JUN EP300

5.83e-053154233966634
Pubmed

Single cell RNA analysis of the left-right organizer transcriptome reveals potential novel heterotaxy genes.

SYNE1 SPARCL1

5.83e-053154237393374
Pubmed

NF-κB- and AP-1-mediated DNA looping regulates osteopontin transcription in endotoxin-stimulated murine macrophages.

JUN EP300

5.83e-053154221257959
Pubmed

The temporal and spatial expression pattern of myosin Va, Vb and VI in the mouse ovary.

MYO5A MYO5B

5.83e-053154216713372
Pubmed

Activities of transmitted/founder and chronic clade B HIV-1 Vpu and a C-terminal polymorphism specifically affecting virion release.

BST2 BTRC

5.83e-053154224574397
Pubmed

Expression and regulation of 1-acyl-sn-glycerol- 3-phosphate acyltransferases in the epidermis.

AGPAT1 AGPAT2

5.83e-053154216150824
Pubmed

Astrocyte Elevated Gene 1 Interacts with Acetyltransferase p300 and c-Jun To Promote Tumor Aggressiveness.

JUN EP300

5.83e-053154227956703
Pubmed

CCR5, GPR15, and CXCR6 are major coreceptors of human immunodeficiency virus type 2 variants isolated from individuals with and without plasma viremia.

GPR15 CCR5

5.83e-053154215650194
Pubmed

Cigarette smoke extract regulates cytosolic phospholipase A2 expression via NADPH oxidase/MAPKs/AP-1 and p300 in human tracheal smooth muscle cells.

JUN EP300

5.83e-053154221268080
Pubmed

Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers in Han Chinese.

LRFN2 DNAH11

5.83e-053154223103227
Pubmed

Stabilization of FASN by ACAT1-mediated GNPAT acetylation promotes lipid metabolism and hepatocarcinogenesis.

ACAT1 GNPAT

5.83e-053154231974474
Pubmed

Antiapoptotic properties of MALT1 protease are associated with redox homeostasis in ABC-DLBCL cells.

JUN GLS

5.83e-053154231556968
Pubmed

Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu.

BST2 BTRC

5.83e-053154220980512
Pubmed

Structural insights into functional overlapping and differentiation among myosin V motors.

MYO5A MYO5B

5.83e-053154224097982
Pubmed

Differential regulation of c-Jun-dependent transcription by SUMO-specific proteases.

JUN EP300

5.83e-053154215701643
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

RELN MYO5A SYNE1 NFKBID CCT2 SRGAP2 WAC KLHL7 SLF2 CADPS GLS MTMR3 DHX35 ANKRD24 SPARCL1 EP300 BTRC

5.92e-0512851541735914814
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CCDC14 RANBP2 MYO5A MYO5B RICTOR CCT2 VPS25 ITPR3 TDRD3 PTPRH MTMR3 UBR3 HADHB HERC1 BTRC

7.00e-0510491541527880917
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

RANBP2 MYO5A ACAT1 SRGAP2 STK3 TDRD3 CELF2 KLHL7 TLN1 DHX35 PHF10 CNN2

9.83e-057241541236232890
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

RGPD2 RANBP2 ANKFY1 SLC4A8 MYO5A CENPF SYNE1 KSR2 SRGAP2 TENM2 TDRD3 CELSR2 KLHL7 KLC1

1.04e-049631541428671696
Pubmed

SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player.

CHRNA9 PLA2G6

1.16e-044154231019507
Pubmed

Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII.

CHMP6 VPS25

1.16e-044154216371348
Pubmed

Structurally distinct modes of recognition of the KIX domain of CBP by Jun and CREB.

JUN EP300

1.16e-044154212437352
Pubmed

The F-box protein beta-TrCp1/Fbw1a interacts with p300 to enhance beta-catenin transcriptional activity.

EP300 BTRC

1.16e-044154219297328
Pubmed

Recent progress in antiretrovirals--lessons from resistance.

BST2 CCR5

1.16e-044154218468560
Pubmed

Sp1 deacetylation induced by phorbol ester recruits p300 to activate 12(S)-lipoxygenase gene transcription.

JUN EP300

1.16e-044154216478997
Pubmed

Myosin V transports secretory vesicles via a Rab GTPase cascade and interaction with the exocyst complex.

EXOC6 MYO5A

1.16e-044154222172676
Pubmed

The transmembrane domain of HIV-1 Vpu is sufficient to confer anti-tetherin activity to SIVcpz and SIVgor Vpu proteins: cytoplasmic determinants of Vpu function.

BST2 BTRC

1.16e-044154223514615
Pubmed

Preservation of tetherin and CD4 counter-activities in circulating Vpu alleles despite extensive sequence variation within HIV-1 infected individuals.

BST2 BTRC

1.16e-044154224465210
Pubmed

Structural basis of myosin V Rab GTPase-dependent cargo recognition.

MYO5A MYO5B

1.16e-044154224248336
Pubmed

Alternative splicing in class V myosins determines association with Rab10.

MYO5A MYO5B

1.16e-044154219008234
Pubmed

p300 cooperates with c-Jun and PARP-1 at the p300 binding site to activate RhoB transcription in NSC126188-mediated apoptosis.

JUN EP300

1.16e-044154224636898
Pubmed

Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP.

JUN EP300

1.16e-044154211278891
Pubmed

SARM inhibits both TRIF- and MyD88-mediated AP-1 activation.

TICAM1 JUN

1.16e-044154220306472
Pubmed

p300 modulates ATF4 stability and transcriptional activity independently of its acetyltransferase domain.

EP300 BTRC

1.16e-044154216219772
Pubmed

CHMP7, a novel ESCRT-III-related protein, associates with CHMP4b and functions in the endosomal sorting pathway.

CHMP6 VPS25

1.16e-044154216856878
Pubmed

DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.

COL4A1 SYNE1 CCDC141

1.23e-0422154312812986
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RANBP2 MYO5A ACAT1 CENPF INTS1 CCT2 ITPR3 BPTF TLN1 SMARCA2 STAG2

1.68e-046531541122586326
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

RICTOR SRGAP2 CPT2 TUBGCP6 ASMTL OSBPL11

1.72e-04183154631932471
Pubmed

Expression of chemokines and their receptors in human and simian astrocytes: evidence for a central role of TNF alpha and IFN gamma in CXCR4 and CCR5 modulation.

GPR15 CCR5

1.93e-045154212555203
Pubmed

Tcl1 functions as a transcriptional regulator and is directly involved in the pathogenesis of CLL.

JUN EP300

1.93e-045154219064921
Pubmed

Prohibitin and the SWI/SNF ATPase subunit BRG1 are required for effective androgen antagonist-mediated transcriptional repression of androgen receptor-regulated genes.

SMARCA2 EP300

1.93e-045154218487222
Pubmed

Upregulation of the matrix metalloproteinase-1 gene by the Ewing's sarcoma associated EWS-ER81 and EWS-Fli-1 oncoproteins, c-Jun and p300.

JUN EP300

1.93e-045154214550555
Pubmed

The C-terminus of human glutaminase L mediates association with PDZ domain-containing proteins.

GLS2 GLS

1.93e-045154211163757
Pubmed

The cytosolic protein talin induces an intermediate affinity integrin alphaLbeta2.

ICAM3 TLN1

1.93e-045154217591777
Pubmed

Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis.

JUN EP300

1.93e-045154210567390
Pubmed

c-Jun interacts with the corepressor TG-interacting factor (TGIF) to suppress Smad2 transcriptional activity.

JUN EP300

1.93e-045154211371641
Pubmed

Cocaine-induced seizure thresholds: quantitative trait loci detection and mapping in two populations derived from the C57BL/6 and DBA/2 mouse strains.

MYO5A SCN8A

1.93e-045154210734168
GeneFamilyMyosins, class V

MYO5A MYO5B

1.06e-04310821100
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

RANBP2 MYO5A SYNE1 ICAM3 MARCHF7 RICTOR WAC JAK3 BPTF EEF1G SAMD9L CELF2 USP42 SLF2 BST2 TLN1 GLS CRTAM SMARCA2 LPGAT1 CCR5 HERC1 HNRNPLL STAG2 EP300 CNN2 KLC1

1.45e-07149215327M40023
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 PPFIA2 KSR2 TENM2 CADPS GLS SCN8A PAM

4.60e-071981548c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 KSR2 TENM2 CELF2 CADPS GLS SCN8A PAM

4.60e-0719815488ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

SYNE1 KSR2 TENM2 CELF2 CADPS GLS SCN8A HERC1

4.96e-07200154848d801219bc771d6c7e151dc88ca4c179988de85
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A TENT5A JUN GLS MED12L OSBPL11 MAML2

2.62e-0617515471ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MPC1L SYNE1 JUN BST2 TLN1 SPARCL1 CNN2

2.93e-0617815470fb36679cddc9ed8f4b5b34e174d5133c2ea1c76
ToppCellControl-B_activate-7|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MS4A4A SLF2 SCN8A MED12L CORIN HIGD2B

3.02e-061151546cc2f8fb0cbb72b241b65a69195aac0507bddf2e2
ToppCellRV|World / Chamber and Cluster_Paper

GABRB1 ACACB TENT5A CCDC141 TENM2 HADHB CFAP61

3.28e-061811547bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN KIF26B PPFIA2 MROH2A ADGRV1 CPS1 DNAH11

3.65e-0618415472cbed6462fea2622871bb7e49b0df3d984239281
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUN SAMD9L SLF2 BST2 TLN1 STAG2 EP300

3.65e-0618415471154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN KIF26B PPFIA2 MROH2A ADGRV1 CPS1 DNAH11

3.65e-061841547ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN KIF26B PPFIA2 MROH2A ADGRV1 CPS1 DNAH11

3.65e-0618415472b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

GABRB1 ACACB CCDC141 TENM2 KLHL7 HADHB CFAP61

4.06e-06187154778cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellLV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

ACACB CCDC141 TENM2 KLHL7 CORIN HADHB CFAP61

4.21e-0618815470758b474457efa36488e0195f7357100f4b6a090
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

GABRB1 ACACB CCDC141 TENM2 KLHL7 CORIN CFAP61

4.51e-061901547de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

ACACB CCDC141 TENM2 KLHL7 PAM CORIN HADHB

4.67e-06191154725f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 PLXND1 JUN BST2 SMARCA2 SPARCL1 ENG

4.83e-0619215473c8603f977de34ee0d2bb50635f6722112a6a4db
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

FBXL13 SYNE1 CFAP61 DTHD1 CFAP69 DNAH6 DNAH11

5.00e-061931547ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_activate-7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF549 WDFY4 SLF2 SCN8A HIGD2B ABCG8

5.12e-061261546518a6e4919981b556ce6b451a91270dba976bc75
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5A SRGAP2 PLXND1 CCDC141 WDFY4 MS4A4A CELF2

5.17e-061941547c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5A NFKBID SRGAP2 CCDC141 WDFY4 MS4A4A CELF2

5.35e-061951547247803cf58c6d9c561a52aa34e581188ddad197e
ToppCellCerebellum-Endothelial|Cerebellum / BrainAtlas - Mouse McCarroll V32

COL4A1 EEF1G SAMD9L BST2 GSDMD TLN1 CNN2

5.35e-0619515472192fd9b4682054776f0716933aed5a4a9412657
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

COL4A1 EXOC6 RELN PAM HERC1 ZNF160 ENG

5.53e-061961547e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5A SRGAP2 PLXND1 CCDC141 WDFY4 MS4A4A CELF2

5.53e-061961547cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCellmild-dn_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CCDC14 CENPF CCDC141 GLS CRTAM CCR5 DTHD1

5.72e-06197154707a1f59c83b748825e0708cd1cc7b63a2cb856cc
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JUN CELF2 PAM CORIN SPARCL1 OTULINL CNN2

5.91e-06198154763f7d25201613bd3404c28fb936954190bca91d3
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JUN CELF2 PAM CORIN SPARCL1 OTULINL CNN2

5.91e-061981547d1e1bdd36c84e1bac21ba137f018defe98456a8c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 KSR2 TENM2 CELF2 CADPS GLS SCN8A

5.91e-0619815476d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 RICTOR BPTF CELF2 GLS HERC1 DTHD1

6.11e-061991547f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T|COVID-19_Mild / Disease, condition lineage and cell class

CCDC141 ITPR3 SAMD9L PAM CCR5 DTHD1 CNN2

6.11e-061991547f307d4887b28cf60a591439e278fd668409cb104
ToppCellControl-B_activate-7|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MS4A4A SLF2 SCN8A MED12L CORIN HIGD2B

6.13e-061301546d3343c19d61928f18e7d707eda5dec6e0fd2a9a2
ToppCellMacroglial-Astrocytes-SLC14A1---|Macroglial / cells hierarchy compared to all cells using T-Statistic

GABRB1 ACACB SYNE1 ADGRV1 TENM2 CELF2 SPARCL1

6.31e-062001547d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCellMacroglial-Astrocytes-SLC14A1----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

GABRB1 ACACB SYNE1 ADGRV1 TENM2 CELF2 SPARCL1

6.31e-062001547f861509b54185d89931db64da1b9d81986cc7938
ToppCellMacroglial-Astrocytes-SLC14A1|Macroglial / cells hierarchy compared to all cells using T-Statistic

GABRB1 ACACB SYNE1 ADGRV1 TENM2 CELF2 SPARCL1

6.31e-06200154716f468217427921fa18c6d078ffa990eb019b257
ToppCellMacroglial-Astrocytes-SLC14A1--|Macroglial / cells hierarchy compared to all cells using T-Statistic

GABRB1 ACACB SYNE1 ADGRV1 TENM2 CELF2 SPARCL1

6.31e-0620015470442894c39eec69850c090957a5dc7bcecd21e04
ToppCellMacroglial-Astrocytes-SLC14A1-|Macroglial / cells hierarchy compared to all cells using T-Statistic

GABRB1 ACACB SYNE1 ADGRV1 TENM2 CELF2 SPARCL1

6.31e-06200154701819446deeab9054f5cfe889d53bb49d137dbc0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYO5B SYNE1 PLXND1 FAM135B ITPR3 DTHD1

1.44e-0515115460cc2f4aec3dae4603fa831f22c40f897e68b34e2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYO5B SYNE1 PLXND1 FAM135B ITPR3 DTHD1

1.44e-051511546b545823113a3450c5f841f7de48bf0937593544f
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPGRIP1 RGPD2 STARD8 MYO5A UBR3 PLA2G6

1.50e-0515215460652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCellfacs-SCAT-Fat-3m-Myeloid-myeloid_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 STARD8 MYO5A NFKBID CCR5 OTULINL

2.46e-0516615468395c74db8e4e54af97a3f2b75cb75171140ec31
ToppCellfacs-SCAT-Fat-3m-Myeloid|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 STARD8 MYO5A NFKBID CCR5 OTULINL

2.46e-05166154676807edc5620514b53a14be354b84c54c112b8f9
ToppCellfacs-SCAT-Fat-3m-Myeloid-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 STARD8 MYO5A NFKBID CCR5 OTULINL

2.46e-051661546645b842b94b8d2f4b26c2623f8589f56bd782c26
ToppCelldroplet-Liver-Npc-18m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MYO5A WDFY4 OTULINL DTHD1 CNN2

2.64e-051681546ce5e92a1df3acfa5cd8d5a134e4af231dc592a13
ToppCelldroplet-Liver-Npc-18m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 MYO5A WDFY4 OTULINL DTHD1 CNN2

2.64e-05168154622c89d4eb44573f6301069ec7ca7cbd0dd958403
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MACC1 ANKFY1 TDRD3 POMGNT2 MAML2 OTULINL

2.73e-051691546665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MACC1 ANKFY1 TDRD3 POMGNT2 MAML2 OTULINL

2.73e-0516915466614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

INTS1 PLXND1 CCDC141 TUBGCP6 RALGPS1 MAML2

3.01e-051721546a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCellPND07-28-samps-Myeloid-Macrophage-CD163+_Macrophage|PND07-28-samps / Age Group, Lineage, Cell class and subclass

STARD8 MYO5A TENT5A SRGAP2 OPHN1 CCR5

3.01e-0517215469a659442dc41bd2a4361a7e38a7ee37a39781667
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A TENT5A JUN GLS OSBPL11 MAML2

3.11e-051731546869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A TENT5A JUN GLS OSBPL11 MAML2

3.11e-0517315460672bd8a4a9d18af343d01f09253fb3388896c10
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A TENT5A JUN GLS OSBPL11 MAML2

3.11e-051731546870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

INTS1 CCDC141 HIBADH TUBGCP6 RALGPS1 MAML2

3.31e-051751546f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STARD8 MYO5A OPHN1 BST2 CCR5 OTULINL

3.76e-051791546fae869fb0a91428481bf8a9c111dcc639e2b4278
ToppCellLV|World / Chamber and Cluster_Paper

GABRB1 CCDC141 TENM2 KLHL7 CORIN CFAP61

3.88e-0518015465ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZGRF1 PPFIA2 PLXND1 SPARCL1 MAML2 ENG

4.00e-051811546fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GABRB1 SLC4A8 ACACB PPFIA2 ADGRV1 HIBADH

4.25e-05183154631ab55d5f3639f5964541d5eae23044dbda3356e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A8 ACACB PPFIA2 ADGRV1 HIBADH RALGPS1

4.52e-051851546898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GABRB1 SLC4A8 ACACB PPFIA2 HIBADH RALGPS1

4.80e-051871546b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCellSubstantia_nigra-Endothelial|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

COL4A1 STARD8 SAMD9L BST2 ENG CNN2

5.09e-051891546bef8234bd9c4d6e3cdef0791d8066b39ba56ebba
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

CCDC141 TENM2 KLHL7 CORIN HADHB CFAP61

5.09e-0518915469c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

ACACB CCDC141 TENM2 KLHL7 HADHB CFAP61

5.09e-0518915465e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell10x5'-blood-Lymphocytic_T_CD8-Trm/em_CD8|blood / Manually curated celltypes from each tissue

SYNE1 CRTAM CCR5 DTHD1 HNRNPLL CNN2

5.24e-051901546e1f474dc36bf9eaf457b14a8761d287904754cdc
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

ACACB CCDC141 TENM2 KLHL7 PAM HADHB

5.24e-051901546fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCelldroplet-Heart|droplet / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STARD8 SYNE1 PLXND1 BST2 SPARCL1 ENG

5.55e-05192154667a7e07a11091120edbccf739836235c422ec9c6
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

ACACB CCDC141 TENM2 KLHL7 PAM HADHB

5.55e-051921546ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 PLXND1 JUN BST2 SMARCA2 SPARCL1

5.55e-051921546e4dd24aefdf13cd4206714f02fde2288f3173ffc
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RANBP2 JAK3 CELF2 GLS MAML2 HERC1

5.55e-05192154647646d7e4990be85072987f92bf18d52f8da752e
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 CENPF JUN BST2 SMARCA2 SPARCL1

5.55e-0519215461a3f24607cb49aa610c183f4c2b7d735f484a3a4
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MACC1 MYO5B ADGRV1 CCDC141 ITPR3 CELSR2

5.55e-05192154629f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 CENPF JUN BST2 SMARCA2 SPARCL1

5.55e-051921546c8dcd75d695d09adff083af8d5a64cf15fe027d4
ToppCellE18.5-Endothelial-Endothelial_blood-vessel|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 CENPF JUN BST2 SMARCA2 SPARCL1

5.55e-051921546a502e95f78f96ed060654a769c6a0cc5dc5fcfd9
ToppCellE18.5-Endothelial|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 CENPF JUN BST2 SMARCA2 SPARCL1

5.55e-051921546cb55d30880237ab8dccf7f7bd31eb7dc5aba0583
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRGAP2 OPHN1 JUN MED12L OSBPL11 CCR5

5.72e-0519315469c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCellmoderate-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SRGAP2 TGM1 SAMD9L BST2 CCR5 HNRNPLL

5.72e-05193154622455801194bd8c73c5c397f5eac4f723429c383
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 PLXND1 JUN BST2 SMARCA2 SPARCL1

5.88e-0519415469235849c7ef3236454eced413acff6274e991a0e
ToppCellE16.5-Endothelial|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 PLXND1 JUN BST2 SMARCA2 SPARCL1

5.88e-051941546c048b7e08a08bb645a28c5b904bd87304d7a4f55
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 JUN BST2 SMARCA2 SPARCL1 ENG

5.88e-0519415462c78e754cac848fd47172f94e392749eb0ab50d4
ToppCellE16.5-Endothelial-Endothelial_blood-vessel|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 PLXND1 JUN BST2 SMARCA2 SPARCL1

5.88e-0519415467062b152367987aba12a2f6f653b647c74b4e160
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYO5A KSR2 GLS SCN8A HERC1 KLC1

5.88e-0519415468aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 JUN BST2 SMARCA2 SPARCL1 ENG

5.88e-05194154692a8e6e3e3f6fd9dacb723b58e7a8b63473e403e
ToppCellCV-Severe-6|Severe / Virus stimulation, Condition and Cluster

JUN SAMD9L TLN1 CRTAM RIC8A ZNF160

5.88e-051941546d33be6ed1de907aeea0c2dce09796556b8efdd4e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5A PLXND1 CCDC141 WDFY4 MS4A4A OTULINL

5.88e-0519415461dce6d4b6ac41f80677e3e4c335a4f383bd76f85
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 PLXND1 JUN BST2 SMARCA2 SPARCL1

5.88e-051941546855ddaf1ec91e6fe1f1617900216a5742e96dda2
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 STARD8 JUN BST2 SMARCA2 ENG

5.88e-051941546c6cee7d15af76f9a60d7f414ef0bcc1735c47b7a
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD8-Trm/em_CD8|bone_marrow / Manually curated celltypes from each tissue

JUN CRTAM CCR5 DTHD1 HNRNPLL CNN2

6.05e-051951546ed4e2275dac47cc9fb9c381e3f80fed0ce50b074
ToppCellcontrol-Lymphoid-Treg|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PLXND1 JAK3 CELF2 USP42 PAM MAML2

6.05e-05195154666959ae839eb60a573da06bdd227090ebb5bb9ed
ToppCellmild-dn_T|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CCDC14 CENPF CCDC141 CRTAM CCR5 DTHD1

6.05e-051951546158f0f229bad71cc9b06b7399168982bbbbd1d47
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 CENPF PLXND1 JUN BST2 SPARCL1

6.05e-051951546eca24039bde02f4677f1f89a373f501c649ec2a5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5A CCDC141 WDFY4 MS4A4A CELF2 OTULINL

6.05e-05195154634a9462f4e843f3065cc58c17ad71c1b5b836ae1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 KSR2 TENM2 CADPS GLS SCN8A

6.23e-051961546676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE1 SAMD9L TLN1 CRTAM CCR5 DTHD1

6.23e-05196154617f17edadafdad9f24e88d708d7e1c765503131c
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A1 SLC4A8 SCN8A CORIN SPARCL1 OTULINL

6.23e-0519615466708026bafd19c35c5c4e81911344d36a0f508cd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5A NFKBID SRGAP2 WDFY4 MS4A4A CELF2

6.40e-0519715468af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCell3'-Child09-12-SmallIntestine-Endothelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A1 RELN STARD8 PLXND1 SPARCL1 ENG

6.40e-05197154686a02fd7b4762b3278e5e60b5483b5fc1206e597
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JUN CELF2 CORIN SPARCL1 OTULINL CNN2

6.59e-051981546a73534b6ca202c277a70a52281d5b97a3e6cb8ef
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 KSR2 CELF2 CADPS GLS SCN8A

6.59e-0519815464ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PPFIA2 KSR2 CADPS GLS SCN8A HERC1

6.59e-0519815460ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellSevere-CD4+_T_Exhausted|World / Disease group and Cell class

MYO5A ICAM3 JAK3 CCR5 HNRNPLL CNN2

6.77e-051991546467c34893dd7d1a8a1c101c966f034cc04b9bcbd
ToppCellSevere-CD4+_T_Exhausted|Severe / Disease group and Cell class

MYO5A ICAM3 JAK3 CCR5 HNRNPLL CNN2

6.77e-051991546dc6b0291714e2b9501c0796a63678bfb9d1b1052
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NFKBID SRGAP2 WDFY4 JAK3 MS4A4A SAMD9L

6.77e-051991546841338719d042247966867ac608146395eb8c4d9
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC14 SYNE1 ADGRV1 CCDC141 ITPR3 GLS

6.77e-0519915462dc33804f6691d7c9682e6c9b885e945fb97fc36
ComputationalGenes in the cancer module 249.

ACAT1 CPT2 TGM1 HADHB

3.71e-0522954MODULE_249
DrugFludrocortisone acetate [514-36-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A

CHRNA9 ACACB PLXND1 CPS1 JAK3 TLN1 GLS ZER1 SPARCL1 BTRC

9.19e-07197153102328_UP
Diseaselung carcinoma, squamous cell carcinoma, gastric carcinoma

LRFN2 DNAH11

2.43e-0521462EFO_0000178, EFO_0000707, EFO_0001071
DiseaseAcute necrotizing encephalopathy of childhood

RANBP2 CPT2

2.43e-0521462C4706387
Diseasebrain disease (is_implicated_in)

RANBP2 TICAM1 CPT2

2.53e-05121463DOID:936 (is_implicated_in)
Diseasethreonine measurement

GLS2 CPS1 MROH2B GLS

3.35e-05371464EFO_0009775
Diseasesystolic blood pressure, response to cold pressor test

FBXL13 CCDC141

1.45e-0441462EFO_0005404, EFO_0006335
Diseasepyroglutamine measurement

RELN MYO5A CPS1 DNPEP

1.98e-04581464EFO_0005408
DiseaseCerebellar Ataxia

SYNE1 SCN8A

2.41e-0451462C0007758
DiseaseBladder Neoplasm

ANKFY1 BPTF RALGPS1 STAG2 EP300

6.76e-041401465C0005695
DiseaseMalignant neoplasm of urinary bladder

ANKFY1 BPTF RALGPS1 STAG2 EP300

6.98e-041411465C0005684
DiseaseAlzheimer disease

RELN FBXL13 SLC4A8 CPS1 TENM2 MS4A4A CELF2 MED12L CNN2

7.22e-044851469MONDO_0004975
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

EXOC6 ACACB BPTF CELSR2 ABCG8 DNAH11

7.26e-042151466EFO_0008317, EFO_0008591
Diseasevery low density lipoprotein cholesterol measurement, lipid measurement

EXOC6 ACACB BPTF CELSR2 ABCG8 DNAH11

8.18e-042201466EFO_0004529, EFO_0008317
Diseaseglycosyl-N-palmitoyl-sphingosine (d18:1/16:0) measurement

GABRB1 CORIN

8.56e-0491462EFO_0800476
Diseasevery low density lipoprotein cholesterol measurement, phospholipid measurement

EXOC6 ACACB BPTF CELSR2 ABCG8 DNAH11

1.01e-032291466EFO_0004639, EFO_0008317
Diseasecortical surface area measurement

EXOC6 RELN FBXL13 GLS2 KIF26B MARCHF7 PLXND1 ADGRV1 CPS1 TENM2 CELF2 CADPS RALGPS1 GLS PAM DNAH11

1.05e-03134514616EFO_0010736
Diseaseprostate adenocarcinoma (is_marker_for)

JUN PAM

1.07e-03101462DOID:2526 (is_marker_for)
Diseaseglutamine measurement, amino acid measurement

GLS2 CPS1

1.30e-03111462EFO_0005134, EFO_0009768
Disease3-methylglutarylcarnitine (2) measurement

CPS1 CPT2

1.30e-03111462EFO_0800074
Diseaseglutamine measurement

GLS2 CPS1 TSFM GLS

1.40e-03971464EFO_0009768
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

CELSR2 ZER1 ABCG8 DNAH11

1.50e-03991464EFO_0004611, EFO_0007878
Diseasefatty acid measurement

EXOC6 ACACB MYO1H BPTF EEF1G CELSR2 LPGAT1 ABCG8

1.53e-034361468EFO_0005110
Diseaselymphangioleiomyomatosis (is_marker_for)

RICTOR GLS

1.55e-03121462DOID:3319 (is_marker_for)
Diseaseautistic disorder (is_marker_for)

GABRB1 RELN

1.55e-03121462DOID:12849 (is_marker_for)
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

CELSR2 ZER1 ABCG8 DNAH11

1.68e-031021464EFO_0004329, EFO_0004611
Diseaseinsomnia measurement

MYO1H KSR2 MARCHF7 ITPR3 MED12L PAM EP300 DNAH11

1.69e-034431468EFO_0007876
Diseasexanthine measurement

KSR2 CELF2

1.83e-03131462EFO_0010548
Diseasegallbladder cancer (is_implicated_in)

RICTOR CCR5

1.83e-03131462DOID:3121 (is_implicated_in)
Diseasevery low density lipoprotein cholesterol measurement

EXOC6 ACACB BPTF CELSR2 ABCG8 DNAH11

1.92e-032601466EFO_0008317
Diseasemetabolite measurement

GLS2 CPS1 CPT2 WDFY4 TUBGCP6 BPTF NBAS OTULINL ABCG8

1.95e-035601469EFO_0004725
Diseasefertility measurement

CCDC141 NBAS

2.13e-03141462EFO_0006923
Diseaseunipolar depression, mood disorder, response to antidepressant

SLC4A8 SCN8A

2.13e-03141462EFO_0003761, EFO_0004247, GO_0036276
DiseaseCiliopathies

RPGRIP1 ADGRV1 BBS10 DNAH11

2.21e-031101464C4277690
Diseasesleep duration

COL4A1 RELN KSR2 SRGAP2 TENM2 PAM BTRC

2.23e-033621467EFO_0005271
Diseasesusceptibility to common cold measurement

MYO5A RALGPS1 SPARCL1

2.45e-03541463EFO_0008417
DiseaseWalker-Warburg congenital muscular dystrophy

COL4A1 POMGNT2

2.45e-03151462C0265221
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

ACACB MYO1H BPTF CELSR2 PLA2G6 ABCG8

2.58e-032761466EFO_0004612, EFO_0020943
Diseasefactor XI measurement, coronary artery disease

COL4A1 CELSR2 ZNF160 ABCG8

2.60e-031151464EFO_0001645, EFO_0004694
DiseaseMalignant neoplasm of breast

STARD8 MAN2C1 CENPF SYNE1 TICAM1 OR1N1 JUN MTMR3 OSBPL11 RIC8A HADHB SPOCD1 EP300

2.68e-03107414613C0006142
Diseaseglutarylcarnitine (C5-DC) measurement

CPS1 CPT2

3.15e-03171462EFO_0800030
Diseasephospholipids in VLDL measurement

EXOC6 CELSR2 ABCG8

3.15e-03591463EFO_0022301
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

ACACB CPS1 BPTF CELSR2 PLA2G6 ABCG8

3.35e-032911466EFO_0008317, EFO_0020946
Diseasefree cholesterol in VLDL measurement

EXOC6 CELSR2 ABCG8

3.46e-03611463EFO_0022276
Diseasealcohol consumption measurement

RELN SLC4A8 ACACB ADGRV1 CPS1 HIBADH TENM2 FAM135B NBAS CADPS RALGPS1 SCN8A EP300 ABCG8

3.52e-03124214614EFO_0007878
Diseasecoronary artery disease, plasminogen activator inhibitor 1 measurement

COL4A1 CELSR2 ABCG8

3.79e-03631463EFO_0001645, EFO_0004792
Diseaseurolithiasis

CPS1 HIBADH STK3

3.79e-03631463MONDO_0024647
DiseaseChronic myeloproliferative disorder

CENPF JAK3

3.93e-03191462C1292778
DiseaseDisorder of eye

COL4A1 RPGRIP1 ADGRV1 BBS10 KLHL7

4.16e-032121465C0015397
Diseaselow density lipoprotein cholesterol measurement, physical activity

CELSR2 ABCG8 DNAH11

4.32e-03661463EFO_0003940, EFO_0004611
Diseaseblood lead measurement

SRGAP2 HIBADH CADPS

4.32e-03661463EFO_0007040
Diseaseglaucoma (is_marker_for)

JUN CCR5

4.36e-03201462DOID:1686 (is_marker_for)
Diseasemaximal midexpiratory flow rate

TUBGCP6 MED12L

4.36e-03201462EFO_0004313
Diseasecitrulline measurement

KIF26B CPS1

4.36e-03201462EFO_0009777
DiseaseGlobal developmental delay

COL4A1 INTS1 NBAS STAG2

4.38e-031331464C0557874
Diseaseobesity (implicated_via_orthology)

ACAT1 PLXND1 ITPR3 STK3 MED12L

4.41e-032151465DOID:9970 (implicated_via_orthology)
Diseaseplatelet component distribution width

COL4A1 EXOC6 STARD8 SYNE1 CPS1 PTPRH TLN1 PLA2G6 HERC1 PIF1

4.45e-0375514610EFO_0007984
DiseaseSeizures

COL4A1 ACAT1 TSFM MED12L PAM

4.67e-032181465C0036572
DiseaseMammary Carcinoma, Human

STARD8 MAN2C1 CENPF SYNE1 JUN RIC8A HADHB EP300

4.73e-035251468C4704874
DiseaseMammary Neoplasms, Human

STARD8 MAN2C1 CENPF SYNE1 JUN RIC8A HADHB EP300

4.73e-035251468C1257931
DiseaseMammary Neoplasms

STARD8 MAN2C1 CENPF SYNE1 JUN RIC8A HADHB EP300

4.84e-035271468C1458155
Diseasemean platelet volume

COL4A1 STARD8 GLS2 MYO5A PLXND1 CPS1 CELF2 GLS MAML2 HADHB ABCG8 CNN2

4.87e-03102014612EFO_0004584

Protein segments in the cluster

PeptideGeneStartEntry
AQAATCNHTVMALMA

BST2

86

Q10589
CNHTVMALMASLDAE

BST2

91

Q10589
TMKNVLNHMTHCQSG

EP300

371

Q09472
TMCMLVELHTQSQDR

EP300

1651

Q09472
AMHQSQTMEGCSSPI

CELF2

191

O95319
FMSVCSRVNMQLLHE

CFAP61

241

Q8NHU2
LSQGVMLSHSPICME

CAGE1

41

Q8TC20
QLAMHSIREMACTTG

DNPEP

446

Q9ULA0
CMKNLHNITGVLMTD

AKAP4

386

Q5JQC9
SQCDEISMNLTHVML

ADGRG4

2501

Q8IZF6
NMMQCIAAGHQIVAL

DPH6

16

Q7L8W6
SGLSMMRCLHNFLTD

GSDMD

261

P57764
NMHCSVLLLTCMSVD

GPR15

116

P49685
VLHLRFNNGMMVTCS

BTRC

386

Q9Y297
QLMNITAGTSHVMIS

ADGRV1

4896

Q8WXG9
TLIQATIAFHQTMMC

DNAH11

2681

Q96DT5
TLLIHGAEACLMSMT

ABCG8

416

Q9H221
ASMDTVHHMLLFGCN

PAM

96

P19021
LTIMVMNIHFCGAEA

CHRNA9

316

Q9UGM1
CQCNHMTSFAVLMDV

CELSR2

2351

Q9HCU4
TIQMFMANVLGLDTC

ADCY10

556

Q96PN6
SCLEVMIAHGSNVMS

ANKRD24

96

Q8TF21
DQAMQVTETLGMTHC

CCR5

276

P51681
FGNECLNKMHQVMSI

CHMP6

106

Q96FZ7
MHLIGSATLAMSTIN

MT-ATP6

171

P00846
SQEQCTLMAEMHVVL

BPTF

276

Q12830
CHQSEETMVSMIIAN

BBS10

621

Q8TAM1
CEHVQTQMSLMNDLT

CCDC14

211

Q49A88
MAQMDQELAHTCISK

ECD

546

O95905
AHTVTMACISANQAM

HADHB

131

P55084
SCGMQVSASMISNEA

ENG

411

P17813
SMNLFSHGTRMQIIC

ACRV1

241

P26436
CEAPAMVMAVHSQTI

COL4A1

1551

P02462
SRHSAGELQQMMVEC

CPT2

521

P23786
MACDRLSQSGHMLLN

RANBP2

346

P49792
CANHRITPDMTLQNM

RANBP2

2381

P49792
IHLACSDTFVNNMVM

OR7A2P

186

Q8NGA2
HSLGNNMMCQLSVVE

RALGPS1

341

Q5JS13
LLHGVCMAGDSTMVQ

JAK3

586

P52333
CMAGDSTMVQEFVHL

JAK3

591

P52333
VVMVSGLHQLKMNCS

HNRNPLL

336

Q8WVV9
CEHSKENLMTPSNMG

OPHN1

511

O60890
EAVRNTLSLMHSCGM

GLS

451

O94925
DTLLMCIVTVMNHGL

ITPR3

2456

Q14573
QSLTMFVLIMNGCHI

ACACB

831

O00763
NDTMSDGQTLLHMAI

ANKFY1

616

Q9P2R3
AQSTKLCSMEMGQEH

CADPS

1146

Q9ULU8
SGAQMTIMSQACAER

DDI1

261

Q8WTU0
HQATGDVCTLMMCLQ

LPGAT1

101

Q92604
VCNTLMNVCMGHQDA

MED12L

1011

Q86YW9
DLLMSVCMNCNTHGS

INTS1

386

Q8N201
LLMACHCTNVMAQSV

MPC1L

81

P0DKB6
LDCVHMLLQMGANHT

NFKBID

186

Q8NI38
KVMNHVNSGCQLMLT

JUN

311

P05412
AMHGMTKLTACQVAT

ASMTL

431

O95671
GNMNCRTTMIAHISA

KIF26B

766

Q2KJY2
QTRHENVVLFMGACM

KSR2

716

Q6VAB6
TNSMEETLMQIGCHG

HERC1

3131

Q15751
LLVQQVALGTMMHCQ

TSFM

136

P43897
VALGTMMHCQTLKDQ

TSFM

141

P43897
MTSHQMARVKVAACN

PLXND1

536

Q9Y4D7
KAMNTCGSHLTVVSM

OR2W1

236

Q9Y3N9
SAGSLCHEDHMLNMV

RASGRP4

71

Q8TDF6
PVMITMVCCAHSTNE

GABRB1

16

P18505
CHSMIQETLQVMEAA

TUBGCP6

171

Q96RT7
CMSEMHRVVQESSSG

GLS2

111

Q9UI32
MLTQRCSHGMVEANG

KLHL7

416

Q8IXQ5
ALQILMEGGTHMVCT

POMGNT2

56

Q8NAT1
SNASMLVSMHGAQLV

POMGNT2

336

Q8NAT1
RLENIHLAGQMMHCS

NBAS

1131

A2RRP1
QMSLTEIMNSIHSDA

RICTOR

1486

Q6R327
SACQHLSTSLMQMLL

EXOC6

661

Q8TAG9
LSFMMNHLNSVGDTC

OTULINL

281

Q9NUU6
STMSHMIQFSINLGC

RELN

566

P78509
MFVLQIGSMSQTDSC

RELN

3331

P78509
QMLNATVMNHGDTLT

ICAM3

261

P32942
TMNCMEVETTNLTSG

GRIN3A

416

Q8TCU5
ETLSCSKHMDGQMTQ

MAML2

271

Q8IZL2
NSGHPSCLDMTMELV

PHF10

406

Q8WUB8
TVCNMENVDAMGVHT

CPS1

646

P31327
LMCVNVHLSVSSMAE

DNAH6

2636

Q9C0G6
NSQCSRLMMHTQIAA

HIGD2B

71

Q4VC39
CSSQVSGIHEMMGCI

CCDC141

421

Q6ZP82
DGLMLQHITLLMCSA

GNPAT

466

O15228
LHDQHCQMSSKMSEL

CENPF

1421

P49454
QNGEEHVVLMCSTMR

CRTAM

131

O95727
NFGCSQEILSIAAMM

DHX35

501

Q9H5Z1
TSACMNITHSQCQML

CORIN

136

Q9Y5Q5
ANSCTGIMHLTINDM

FBXL13

346

Q8NEE6
MHDECTPQQTMSSIQ

DTHD1

1

Q6ZMT9
FSQVMTEMVCLHSLG

MACC1

301

Q6ZN28
SNNCHGTMSILMGLD

MS4A4A

171

Q96JQ5
LLHLCEQSFSDMMGN

MARCHF7

646

Q9H992
TGSCIQMVAEEAMCH

MAN2C1

581

Q9NTJ4
MMLPQAALETHCSNI

ASNSD1

246

Q9NWL6
ELTQTFMSCNLITGM

EEF1G

331

P26641
VDSGAQMTIMSQACA

DDI2

251

Q5TDH0
HMDMCSESQVYISIG

FAM135B

491

Q49AJ0
LQHLSTSEVNCTIMM

CFAP69

221

A5D8W1
LGLSEAQVMMALSNH

KLC1

81

Q07866
SGHSDAQTLAMMLQE

PPFIA2

641

O75334
NCEVVFMGMANIHSI

MTMR3

341

Q13615
PCVIVSNHQSILDMM

AGPAT2

91

O15120
SMATMNCLNDCFHIL

OSBPL11

261

Q9BXB4
SCSDTHINEMMVFVL

OR1N1

186

Q8NGS0
CSDTHVNELMIITMG

OR1N2

206

Q8NGR9
SQNLMEMVHCFVALA

MROH2A

366

A6NES4
AMSIHKSQGMTLDCV

PIF1

551

Q9H611
IGLCMPNSAHIMASN

RPGRIP1

216

Q96KN7
MLRLQMTDGHISCTA

TDRD3

1

Q9H7E2
NHRVLLFCQMTSLMT

SMARCA2

1066

P51531
TTASGCELMHTEMQA

SYNE1

2911

Q8NF91
MACDRLSQSGHMLLN

RGPD2

346

P0DJD1
LKGMENMLCISVNSH

SAMD9L

571

Q8IVG5
QTTAMVMRGNCSFHT

SPPL2C

91

Q8IUH8
GCSEMLMAHAVTQLA

CCT2

411

P78371
DMIQSRVTLMAQHGS

TEN1

36

Q86WV5
CQMPLLDSNTSHQIM

TENM2

196

Q9NT68
ASQSLMCGHQDVMVA

ACAT1

136

P24752
HNMGTIHMSEICTEL

WAC

591

Q9BTA9
GCAEMIISMDSSQIH

PLA2G6

266

O60733
NLTVSECQEMHGEFM

SLC4A8

666

Q2Y0W8
FRMMSVHTDCIVSVQ

SLF2

811

Q8IX21
SLHGQCSQVLGMSVM

MROH2B

731

Q7Z745
HLTSLQDAMCETMEQ

RIC8A

506

Q9NPQ8
LSDNMAATQGLSHMI

STARD8

756

Q92502
ATCSMATLNQMHRLG

MRPS12

26

O15235
CNNMLLAISMIGTAE

HIBADH

211

P31937
MDHSTISLQMGTNKC

CNN2

201

Q99439
SLSMGCVMFEVHELN

TMEM244

31

Q5VVB8
GAQTMIEHNSTMLES

STK3

346

Q13188
LDMAVRAMTSHINIC

TMEM269

71

A0A1B0GVZ9
MCTMQAHITQALSNP

USP42

156

Q9H9J4
CRLHKQSSMTVMEAQ

VPS25

41

Q9BRG1
SLGLCHFDMNIISML

ZNF160

46

Q9HCG1
LMSLDISGHMILENC

ZER1

281

Q7Z7L7
ISGHMILENCSISKM

ZER1

286

Q7Z7L7
MLENFSLMASVGCLH

ZNF549

56

Q6P9A3
MQCLMRHLAQAGATV

TAS1R1

256

Q7RTX1
DMSVLNSPRHQSCIM

REV1

406

Q9UBZ9
MGHVLIIVQCFISSM

SLC35A5

231

Q9BS91
NSDSPELINMTGHCM

SAGE1

741

Q9NXZ1
LCDILMIFSHQIMSG

STAG2

791

Q8N3U4
VSNHQSSLDLLGMME

AGPAT1

101

Q99943
MLMTICARIGITNHD

TLN1

111

Q9Y490
DCRLSLHQVNQAMMS

TICAM1

461

Q8IUC6
SEGNMRVHAVDSCMS

SPARCL1

421

Q14515
HNCELLQNMEGASSM

SPOCD1

21

Q6ZMY3
MAQETNHSQVPMLCS

ZFAND6

1

Q6FIF0
IFHDLMACVTMDNLQ

SRGAP2

581

O75044
MACVTMDNLQERALH

SRGAP2

586

O75044
HLTMAQLTGNMESES

FAM170A

261

A1A519
VLTSNAMCDFLMQHI

WDFY4

1401

Q6ZS81
HSVFSMIIMCTILTN

SCN8A

131

Q9UQD0
MVAQLCMNDRTHSSL

UBR3

791

Q6ZT12
TALIQIAQMMASHES

ZGRF1

1621

Q86YA3
GQDLMVSVMLINHSS

TGM1

591

P22735
TMDLVLEMCNTNSIH

TRAPPC13

336

A5PLN9
MTLHGVVNESTVCLM

TENT5A

356

Q96IP4
QSHTLVMLTNCMEAG

PTPRH

911

Q9HD43
QCQSMHSQILGGTMI

LRFN2

521

Q9ULH4
MMCAELNNHFILISG

MYO1H

91

Q8N1T3
RQLNSFHSVMCQHGM

MYO5A

1666

Q9Y4I1
AIIRQMNAFHTVMCD

MYO5B

1656

Q9ULV0