Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PCSK5 FAM89A LPAR5 ZZEF1 TRRAP NR2F2 ADCY9 SH3BP4 ITPR3 SLC7A1 XPO6 INTS11 DEPDC5 GPAT4 TOP3A

5.50e-071105991535748872
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

BDP1 UBR2 ZBTB16 RASA2 NFASC PPHLN1 TRRAP DNAH1 SH3BP4 ARFGEF3 SLC7A1 THRA EFNB2 GTF3C1 FAM13A PTPRR MACF1

9.87e-071489991728611215
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

CUL3 IARS1 RGPD1 PRPF6 FBXL3 GSPT1 KHSRP GTF3C1 FDFT1 KLHL13 SFXN2 DNA2 DDX41 SNRNP200 GPAT4

2.70e-061257991537317656
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZZEF1 TRRAP ADCY9 TFDP1 EDEM3 THRA ZFHX4 P4HA1 ARID2 INTS11 SFXN2 MACF1 DNA2 DDX41

3.40e-061116991431753913
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

NFASC CHD7 ADCY9 STAB1 XPO6 MACF1 SNRNP200

3.88e-0622599712168954
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

UBR2 IARS1 TRRAP NR2F2 TFDP1 KHSRP PHKA2 GTF3C1 ZFHX4 P4HA1 MAPKAPK3 SNRNP200

6.03e-06857991225609649
Pubmed

TRIM38 suppresses migration, invasion, metastasis, and proliferation in non-small cell lung cancer (NSCLC) via regulating the AMPK/NF-κB/NLRP3 pathway.

NLRP3 TRIM38

8.02e-06299237566200
Pubmed

Interference with lysophosphatidic acid receptor 5 ameliorates oxidized low-density lipoprotein-induced human umbilical vein endothelial cell injury by inactivating NOD-like receptor family, pyrin domain containing 3 inflammasome signaling.

LPAR5 NLRP3

8.02e-06299234662522
Pubmed

Acceleration of conduction velocity linked to clustering of nodal components precedes myelination.

GAD1 NFASC

8.02e-06299225561543
Pubmed

A study of recombination between the H-2 (histocompatibility) locus and loci closely linked with it in the house mouse.

ITPR3 THRA

8.02e-0629925309548
Pubmed

A Cul3-based E3 ligase regulates mitosis and is required to maintain the spindle assembly checkpoint in human cells.

CUL3 KLHL13

8.02e-06299218075312
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

ZBTB16 PPHLN1 THRA P4HA1 FDFT1 PDE4DIP MACF1 TRIM38 VCL

1.28e-0549799923414517
Pubmed

Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development.

ZZEF1 KHSRP SLC7A1 SLC5A6 GPAT4

1.86e-0511399530352685
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

PRPF6 ADCY9 TFDP1 SH3BP4 ITPR3 GUF1 EFNB2 P4HA1 FDFT1 MACF1 CARS2 DNA2 SNRNP200 GPAT4 VCL

2.00e-051487991533957083
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FNIP2 UBR2 ARFGEF3 KLHL13 PDE4DIP DZIP3 MACF1 MEGF11

2.22e-0540799812693553
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

CUL3 IARS1 PRPF6 GSPT1 KHSRP PHKA2 GTF3C1 P4HA1 MACF1 TRAPPC3 DDX41 SNRNP200 VCL

2.33e-051149991335446349
Pubmed

Dysregulation of schizophrenia-related aquaporin 3 through disruption of paranode influences neuronal viability.

NFASC AQP3

2.40e-05399230025158
Pubmed

Targeting Cul3-scaffold E3 ligase complex via KLHL substrate adaptors for cancer therapy.

CUL3 KLHL13

2.40e-05399233872809
Pubmed

Linkage relationships of markers on chromosome 17 of the house mouse.

ITPR3 THRA

2.40e-0539921225760
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RASA2 IARS1 PRPF6 CHD7 TRRAP GSPT1 KHSRP GUF1 GTF3C1 INTS11 MACF1 DDX41 SNRNP200 VCL

2.95e-051353991429467282
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

UBR2 PRPF6 TRRAP GTF3C1 P4HA1 SNRNP200

3.25e-0521199617314511
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

UBR2 SIKE1 ZZEF1 TRRAP TRMT6 ARID2

3.34e-0521299633853758
Pubmed

Prenatal phthalate exposure and cord blood DNA methylation.

CUL3 MEGF11

4.79e-05499237120575
Pubmed

BPOZ-2 is a negative regulator of the NLPR3 inflammasome contributing to SARS-CoV-2-induced hyperinflammation.

CUL3 NLRP3

4.79e-05499236936774
Pubmed

Multifaceted role of the Topo IIIα-RMI1-RMI2 complex and DNA2 in the BLM-dependent pathway of DNA break end resection.

DNA2 TOP3A

4.79e-05499225200081
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

LPAR5 CDKL2 IARS1 NFASC PIWIL2 ZZEF1 TRMT6 GTF3C1 P4HA1 SNRNP200

4.85e-05736991029676528
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SLC25A18 PRPF6 CHD7 TRRAP KHSRP GTF3C1 P4HA1 ARID2 INTS11 MACF1 DDX41 SNRNP200

5.94e-051082991238697112
Pubmed

Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome.

SH3BP1 PDE4DIP MACF1

6.23e-052799318685082
Pubmed

Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders.

NR2F2 TFDP1 ZFHX4

6.96e-052899329365100
Pubmed

Notch4 normalization reduces blood vessel size in arteriovenous malformations.

NR2F2 EFNB2

7.98e-05599222261032
Pubmed

Deletion of Rbpj from postnatal endothelium leads to abnormal arteriovenous shunting in mice.

NR2F2 EFNB2

7.98e-05599225209249
Pubmed

Mutations in DEPDC5 cause familial focal epilepsy with variable foci.

GAD1 DEPDC5

7.98e-05599223542697
Pubmed

Control of the negative IRES trans-acting factor KHSRP by ubiquitination.

CUL3 KHSRP

7.98e-05599227899653
Pubmed

Deficiency of the autophagy gene ATG16L1 induces insulin resistance through KLHL9/KLHL13/CUL3-mediated IRS1 degradation.

CUL3 KLHL13

7.98e-05599231515271
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

BDP1 TRRAP GTF3C1 DNA2 DDX41 VCL

8.33e-0525099633536335
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

CUL3 IARS1 PRPF6 BBS9 SH3BP4 KIFAP3 XPO6 DZIP3 TRAPPC3 DDX41 SNRNP200 VCL PMFBP1

9.63e-051321991327173435
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

CUL3 PCSK5 ZZEF1 SH3BP4 PHKA2 GTF3C1 RAD54B DNA2 TOP3A

1.02e-0465099938777146
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

PRPF6 CHD7 TRRAP KHSRP ITPR3 GTF3C1 MACF1 SNRNP200 VCL

1.06e-0465399922586326
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

CUL3 RGPD1 PRPF6 FBXL3 PHKA2 EDEM3 GTF3C1 ARID2 DDX41 SNRNP200 TOP3A VCL

1.10e-041155991220360068
Pubmed

Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.

UBR2 ZZEF1 NR2F2 GUF1 GTF3C1 FDFT1 INTS11 CARS2

1.15e-0451599831617661
Pubmed

A widely expressed betaIII spectrin associated with Golgi and cytoplasmic vesicles.

PCSK5 FAM89B

1.19e-0469929826670
Pubmed

IL-18 is not therapeutic for neovascular age-related macular degeneration.

AQP3 NLRP3

1.19e-04699225473914
Pubmed

The human homologue of the yeast splicing factor prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions.

PRPF6 SNRNP200

1.19e-04699210788320
Pubmed

Abnormal arterial-venous fusions and fate specification in mouse embryos lacking blood flow.

NR2F2 EFNB2

1.19e-04699228931948
Pubmed

KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.

CUL3 DEPDC5

1.19e-04699229769719
Pubmed

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

UBR2 RGPD1 PRPF6 TRRAP KHSRP ARID2 SNRNP200

1.30e-0439099717643375
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

IARS1 PRPF6 CHD7 TRRAP GTF3C1 ARID2 DDX41

1.38e-0439499727248496
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CUL3 NFASC ZZEF1 ADCY9 STAB1 TRMT6 DEPDC5 DNA2

1.39e-0452999814621295
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

UBR2 FKBP9 C1GALT1 ZZEF1 KHSRP EDEM3 GTF3C1 P4HA1 XPO6 FDFT1 SLC5A6 GPAT4

1.58e-041201991235696571
Pubmed

Autonomous and non-autonomous roles for ephrin-B in interneuron migration.

GAD1 EFNB2

1.67e-04799228947178
Pubmed

MILI, a PIWI-interacting RNA-binding protein, is required for germ line stem cell self-renewal and appears to positively regulate translation.

ZBTB16 PIWIL2

1.67e-04799219114715
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

PPHLN1 CHD7 TRRAP NR2F2 KHSRP GTF3C1 SNRNP200

1.76e-0441099726949251
Pubmed

Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.

IARS1 ARFGEF3 XPO6 FDFT1 TRAPPC3

1.83e-0418399523956138
Pubmed

Genome-wide association study of primary dentition pit-and-fissure and smooth surface caries.

KIF6 C1GALT1 BBS9

1.90e-043999324556642
Pubmed

CHD7 cooperates with PBAF to control multipotent neural crest formation.

CHD7 ARID2

2.22e-04899220130577
Pubmed

Molecular identification of venous progenitors in the dorsal aorta reveals an aortic origin for the cardinal vein in mammals.

NR2F2 EFNB2

2.22e-04899224550118
Pubmed

Dual function of the UNC-45b chaperone with myosin and GATA4 in cardiac development.

MYH6 UNC45B

2.22e-04899222553207
Pubmed

The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self-associating activity.

NFASC EFNB2

2.22e-04899211152476
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

SLC7A1 SLC5A6 SLC22A2 VCL

2.37e-0410599430280653
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

PRPF6 CHD7 GSPT1 STAB1 XPO6 MACF1 DDX41 SNRNP200

2.64e-0458299820467437
Pubmed

BRG1 promotes COUP-TFII expression and venous specification during embryonic vascular development.

NR2F2 EFNB2

2.85e-04999223406903
Pubmed

Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment.

GAD1 NFASC

2.85e-04999215479642
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

CUL3 IARS1 PRPF6 CHD7 TRRAP GSPT1 KHSRP GTF3C1 ARID2 DDX41 SNRNP200

3.07e-041103991134189442
Pubmed

Mapping the Genetic Landscape of Human Cells.

BDP1 IARS1 TRRAP SLC7A1 CARS2 DNA2 SNRNP200

3.14e-0445199730033366
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

CHD7 TRRAP TFDP1 TRMT6 GTF3C1 ARID2 RAD54B DDX41

3.54e-0460899836089195
Pubmed

A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells.

CUL3 KLHL13

3.56e-041099217543862
Pubmed

MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs.

ZBTB16 PIWIL2

3.56e-041099220547853
Pubmed

Maternal thyroid hormone is required for parvalbumin neurone development in the anterior hypothalamic area.

GAD1 THRA

3.56e-041099229377458
Pubmed

Assembly of the cochlear gap junction macromolecular complex requires connexin 26.

MYH6 VCL

3.56e-041099224590285
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

CUL3 CYP2C18 CHD7 TRRAP GTF3C1 FAM13A XPO6 DDX41 SNRNP200

3.72e-0477499915302935
Pubmed

Distinct class of putative "non-conserved" promoters in humans: comparative studies of alternative promoters of human and mouse genes.

RAD54B SFXN2 SNRNP200

3.75e-044999317567985
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

IARS1 PRPF6 GTF3C1 P4HA1 ARID2 SNRNP200

3.85e-0433299632786267
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CUL3 SH3BP1 RGPD1 NFASC CHD7 KHSRP PDE4DIP DZIP3 MACF1 TRAPPC3

4.26e-04963991028671696
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

PRPF6 TRRAP KHSRP ARID2 SNRNP200

4.27e-0422099535785414
Pubmed

Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity.

NR2F2 EFNB2

4.34e-041199215875024
Pubmed

PRDM16 regulates arterial development and vascular integrity.

NR2F2 EFNB2

4.34e-041199237324380
Pubmed

Subregional specification of embryonic stem cell-derived ventral telencephalic tissues by timed and combinatory treatment with extrinsic signals.

GAD1 NR2F2

4.34e-041199221289201
Pubmed

Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases.

CUL3 KLHL13

4.34e-041199214528312
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RGPD1 PRKCQ

4.34e-041199234110283
Pubmed

Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice.

MYH6 VCL

4.34e-041199216374517
Pubmed

The thyroid hormone receptor alpha1 protein is expressed in embryonic postmitotic neurons and persists in most adult neurons.

MYH6 THRA

4.34e-041199220739404
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

SLC7A1 SLC5A6 SLC22A2

4.47e-045299326590417
Pubmed

Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.

CHD7 TRRAP TFDP1 GTF3C1

4.60e-0412599432891193
Pubmed

A protein interaction landscape of breast cancer.

UBR2 TFDP1 GSPT1 KHSRP ITPR3 FDFT1 ARID2 MACF1

4.66e-0463499834591612
Pubmed

Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures.

KIFAP3 P4HA1 PRKCQ

4.73e-045399336265442
Pubmed

Transcriptional regulation by the repressor of estrogen receptor activity via recruitment of histone deacetylases.

NR2F2 THRA

5.20e-041299215140878
Pubmed

Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin.

PCSK5 KHSRP

5.20e-041299215606899
Pubmed

The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis.

CUL3 KLHL13

5.20e-041299219995937
Pubmed

Regulation and binding of pregnane X receptor by nuclear receptor corepressor silencing mediator of retinoid and thyroid hormone receptors (SMRT).

NR2F2 THRA

5.20e-041299216219912
Pubmed

Motor phenotypes and molecular networks associated with germline deficiency of Ciz1.

ZBTB16 ZFHX4

5.20e-041299227163549
Pubmed

KEAP1 Mutations Drive Tumorigenesis by Suppressing SOX9 Ubiquitination and Degradation.

CUL3 KLHL13

5.20e-041299233173725
Pubmed

Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.

CUL3 IARS1 GSPT1 KHSRP P4HA1 KLHL13 SNRNP200

5.47e-0449599728581483
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

CUL3 PPHLN1 ARFGEF3 ZFHX4 MAPKAPK3 MACF1

5.98e-0436199626167880
Pubmed

ZMPSTE24 defends against influenza and other pathogenic viruses.

SLC7A1 XPO6

6.13e-041399228246125
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

RGPD1 NFASC

6.13e-041399231427429
Pubmed

Endothelial TIE1 Restricts Angiogenic Sprouting to Coordinate Vein Assembly in Synergy With Its Homologue TIE2.

NR2F2 EFNB2

6.13e-041399237317851
Pubmed

Differential interaction of nuclear receptors with the putative human transcriptional coactivator hTIF1.

NR2F2 THRA

6.13e-04139929115274
Pubmed

Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.

KIF6 ZBTB16

6.13e-041399218846501
Pubmed

The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP.

PRPF6 SNRNP200

6.13e-041399216723661
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

CUL3 RGPD1 PRPF6 GSPT1 GTF3C1 DDX41

6.79e-0437099622922362
CoexpressionNAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP

UBR2 IARS1 PRPF6 GSPT1 SH3BP4 SLC7A1 FAM13A P4HA1 FDFT1 MAPKAPK3 PDE4DIP DZIP3 MACF1 TRIM38 SNRNP200 TOP3A VCL

2.85e-0612159917M41122
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

CUL3 BDP1 UBR2 RASA2 SH3BP1 FAM89B PPHLN1 JAML FBXL3 GVINP1 XPO6 ARID2 PDE4DIP DZIP3 MACF1 PRKCQ TRIM38 SNRNP200

1.09e-0514929918M40023
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500

PCSK5 BDP1 C1GALT1 PRPF6 CHD7 ZFHX4 FDFT1 MAPKAPK3 MACF1 SLITRK6 DNA2 GPAT4

3.12e-064929912Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#3

PCSK5 C1GALT1 ZFHX4 SLITRK6 DNA2 GPAT4

3.91e-05134996Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

CUL3 IARS1 PPHLN1 C1GALT1 PRPF6 CHD7 GSPT1 TRMT6 GVINP1 PTPRR XPO6 FDFT1 DZIP3 PTCH2 PRKCQ SLITRK6 DNA2

6.27e-0512529917facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2

FNIP2 BDP1 PPHLN1 PRPF6 CHD7 GTF3C1 XPO6 ARID2 DZIP3 MACF1 DEPDC5

6.42e-055649911Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

GAD1 ZBTB16 CHD7 NR2F2 SH3BP4 PTPRR PDE4DIP SLITRK6

1.08e-08190998842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Neuronal-GABAergic_neurons|GW19 / Sample Type, Dataset, Time_group, and Cell type.

GAD1 ZBTB16 NR2F2 ADCY9 PTPRR PDE4DIP

4.56e-08889965582fd7bac60c690ecd1f2aff1d446ccb69f79b9
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal-GABAergic_neurons|GW16 / Sample Type, Dataset, Time_group, and Cell type.

GAD1 ZBTB16 NR2F2 ITPR3 PTPRR PDE4DIP

1.81e-061649964d7b2d0980fb4f47721fa2891151e2bd892ccb91
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 ZBTB16 PRPF6 NR2F2 P4HA1 MACF1

2.73e-06176996749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 GAD1 NR2F2 PRELID2 KLHL13 MEGF11

3.64e-0618599608fad1e3c3cc5f1c3eb6629a49c094b628e75a92
ToppCellNeuron-Postmitotic-Inhibitory_Neuron|World / Primary Cells by Cluster

GAD1 ZBTB16 CHD7 NR2F2 PTPRR PDE4DIP

4.37e-061919964dd9c8117c4499ed9bde127baf2598603a82080d
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-SST-MGE1|World / Primary Cells by Cluster

GAD1 ZBTB16 CHD7 NR2F2 PTPRR PDE4DIP

4.50e-06192996bcc499f4c7ba2898ecd9c47bf68c92ed359b81ba
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-SST-MGE1-4|World / Primary Cells by Cluster

GAD1 ZBTB16 CHD7 NR2F2 PTPRR PDE4DIP

4.64e-061939962eb6e4cff4fe3ce564c1581f6f7df4834895aaa9
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR|Neuronal / cells hierarchy compared to all cells using T-Statistic

PCSK5 GAD1 NR2F2 ZFHX4 SLITRK6 MEGF11

5.69e-06200996862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1|Neuronal / cells hierarchy compared to all cells using T-Statistic

PCSK5 GAD1 NR2F2 ZFHX4 SLITRK6 MEGF11

5.69e-06200996a91345f268f13170c27309333603eb82400c9947
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-|Neuronal / cells hierarchy compared to all cells using T-Statistic

PCSK5 GAD1 NR2F2 ZFHX4 SLITRK6 MEGF11

5.69e-06200996d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD1 CHD7 NR2F2 KLHL13 PRKCQ

8.52e-0612499536dfc702a570e1a1a6dde09f38badf9023ea7287
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-FB-2|PND01-03-samps / Age Group, Lineage, Cell class and subclass

UBD NR2F2 FAM13A SLC22A2 MACF1

8.86e-061259956cd741dd1c7ee6b16437cca7c15c99b5c95603fc
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Interneuron|GW23 / Sample Type, Dataset, Time_group, and Cell type.

GAD1 ZBTB16 PTPRR PDE4DIP

1.19e-0563994c10d344bf32a091deb79e1f128f7dd5e9f4abaa3
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD1 NR2F2 PTPRR KLHL13 PRKCQ

1.48e-051399959e9f29f92dbe65b26cc78b3a1c00778c6a701f5b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Interneuron|GW16 / Sample Type, Dataset, Time_group, and Cell type.

GAD1 ZBTB16 PTPRR PDE4DIP

2.78e-05789948ad496ccbffb62a50f195c3789a95d8c80e2272d
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC7A1 SLC5A6 MAPKAPK3 DEPDC5 CARS2

2.83e-05159995f7bccfeffa737f151417bf52ea45111b0957bce9
ToppCellInt-URO-Lymphocyte-T_NK-dnT|Int-URO / Disease, Lineage and Cell Type

ARMC9 AQP3 PRELID2 DZIP3 PRKCQ

4.12e-05172995e70299573da1679d6d286c3a43699cbff76e207d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 NR2F2 PRELID2 KLHL13 MEGF11

4.24e-05173995af85fb9f6e26a044ca4d23e5872039b1a7b73b1b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 NR2F2 PRELID2 KLHL13 MEGF11

4.24e-051739950ba64e5385fe714f876002520f8b5202809bf11e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-5_VIP_KCNJ2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 CHD7 NR2F2 PRELID2 MEGF11

4.35e-05174995fdadac1eaab2c4a67e4832f0901df22e893add6a
ToppCelldroplet-Marrow-nan-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZZEF1 ADCY9 DNAH1 PDE4DIP DEPDC5

4.35e-0517499555cc8300489d11322724159ec7d0e1d32a702e91
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBD STAB1 EFNB2 PTPRR UNC45B

4.98e-05179995a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 NR2F2 ZFHX4 KLHL13 SLITRK6

4.98e-0517999502c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 NR2F2 PRELID2 KLHL13 MEGF11

5.12e-05180995b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 NR2F2 PRELID2 KLHL13 MEGF11

5.25e-051819952f3d04d22d4ac016e61709ea5af3d48885c946c4
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 NR2F2 PRELID2 KLHL13 MEGF11

5.39e-051829957dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 EFNB2 PTPRR UNC45B KLHL13

5.39e-05182995c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 EFNB2 PTPRR UNC45B KLHL13

5.39e-05182995d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 NR2F2 PRELID2 KLHL13 MEGF11

5.53e-05183995e3ffef2b57dc5b96466dccc9cd54ba326ccf378a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 NR2F2 PRELID2 KLHL13 MEGF11

5.53e-051839955e361be3ae3fe05098968e58427630127bd12675
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-SST-MGE1-3|World / Primary Cells by Cluster

GAD1 ZBTB16 NR2F2 PTPRR PDE4DIP

5.68e-05184995907ba412166bcb0526c5be0b06a76b6bd37c5a35
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 ZBTB16 NR2F2 PRELID2 MEGF11

5.82e-0518599516e9ccea0e3b95d90dc48ef74206c805681dac0b
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 NR2F2 PRELID2 KLHL13 MEGF11

5.82e-05185995027020754dbf71b0034791f9a34ae795e3b85f81
ToppCelldroplet-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 STAB1 EFNB2 PTPRR UNC45B

5.82e-05185995eeb6f55a6f79adf80247baa2c4b0df44553557ad
ToppCellBrain_organoid-organoid_Kanton_Nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

ZBTB16 CHD7 NR2F2 EFNB2 FDFT1

5.82e-05185995857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

PCSK5 ADCY9 AGXT2 SLC22A2 TRIM38

6.13e-05187995d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 NR2F2 PRELID2 KLHL13 MEGF11

6.13e-0518799502105c82a9ba79d2f19e002188377fc3440770c2
ToppCellSevere-MAIT|World / Disease group and Cell class

ZBTB16 CHD7 AQP3 JAML THRA

6.61e-051909957a92e0d6a021be23125495927b8571e25c83204a
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

FKBP9 NR2F2 MACF1 SLITRK6 VCL

6.61e-051909951196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 ITPR3 EFNB2 PTPRR UNC45B

6.61e-05190995eae5bcdb8a35f3fba4d25854c1a43f83f80832a2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDKL2 ITPR3 KLHL13 PRKCQ MEGF11

6.61e-051909953fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 ITPR3 EFNB2 PTPRR UNC45B

6.61e-051909953346bfd0474828b3729cffa9f4cc57b04dd30443
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RASA2 POU5F2 AQP3 CYP2U1 PRKCQ

6.61e-0519099569c5c4d5f4fb6e5ae2c9dbf9d209faf093c3f769
ToppCellSevere-MAIT|Severe / Disease group and Cell class

ZBTB16 CHD7 AQP3 JAML THRA

6.61e-051909951c063dc1b62d9f9912aaf8d0297555a6545f5550
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 GAD1 NR2F2 SLITRK6 MEGF11

6.77e-051919957b386512284dfaa0e95358b28ee82632ee965e64
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITPR3 KLHL13 PDE4DIP PRKCQ MEGF11

6.77e-051919955a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITPR3 KLHL13 PDE4DIP PRKCQ MEGF11

6.77e-0519199555ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCellEC|World / Lineage and Cell class

UBD NR2F2 STAB1 PTPRR UNC45B

6.94e-05192995478866dd5b0d6ff3a76d07a17c4b5989dd7a27bb
ToppCellMS-Treg-exh_CD4|MS / Condition, Cell_class and T cell subcluster

FAM89B GUF1 XPO6 PDE4DIP DEPDC5

6.94e-05192995c6722bf142c84ccedd99c1a3344085aecb4cbab4
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

SH3BP1 JAML ADCY9 TRMT6 GPAT4

6.94e-05192995af453a179f3fdd4ae870f1d98a485e8c9fd726ac
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Myeloid-Monocytic-Nonclassical_Monocyte|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

SH3BP1 JAML ADCY9 TRMT6 GPAT4

6.94e-05192995176b9c1dd2c91bca46e12fa5060bfe590dc18246
ToppCelldroplet-Kidney-nan-18m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 GAD1 EFNB2 PTPRR UNC45B

6.94e-05192995144503af50274eaed5cf6effa892c640eab28663
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Myeloid-Monocytic|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

SH3BP1 JAML ADCY9 TRMT6 GPAT4

6.94e-0519299581f93b4c853f176c91b5ddef34238e37047a0e69
ToppCelldroplet-Kidney-nan-18m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 GAD1 EFNB2 PTPRR UNC45B

6.94e-05192995c96736bb3a6bb052678b1b078f7823063ca69e6d
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-MGE2|World / Primary Cells by Cluster

GAD1 ZBTB16 NR2F2 PTPRR PDE4DIP

7.29e-05194995b42fd64b0fb95434a9e4e6586f31d26114a4074b
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-MGE2-10|World / Primary Cells by Cluster

GAD1 ZBTB16 NR2F2 PTPRR PDE4DIP

7.29e-0519499581e7bc6516ab8d02ccd1c76a56a3533b788c27c8
ToppCell(7)_Epithelial_cells|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CDKL2 ARMC9 AQP3 ITPR3 ARFGEF3

7.29e-05194995413e8b9f1e15be363a7f4a8f727af3eeb9e9a928
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBD NR2F2 STAB1 THRA UNC45B

7.29e-05194995e8102c8811333f04de7280b7d9b6b85cebb815ac
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBD NR2F2 STAB1 THRA UNC45B

7.29e-051949954b0d63babb8a46ff45731d5f82b29ccaf6c9402d
ToppCell(7)_Epithelial-B_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CDKL2 ARMC9 AQP3 ITPR3 ARFGEF3

7.65e-05196995345d4cc062b43bca9d506fbf23363469a9ba496f
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Neuronal-INs|6_mon / Sample Type, Dataset, Time_group, and Cell type.

GAD1 ZBTB16 CHD7 NR2F2 PTPRR

7.65e-05196995556e18eae05bf19259fe02848bcc9120aa2a9d29
ToppCell356C-Epithelial_cells-Epithelial-B_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

CDKL2 ARMC9 AQP3 ITPR3 ARFGEF3

7.84e-0519799506ed8f293d4ee89f14dc2f43d6cae93bbc02508a
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.

CUL3 FAM89B NFASC EFNB2 FDFT1

7.84e-0519799586157ba4f9a40a80bab2404684fe5a7b4ee380c5
ToppCell343B-Epithelial_cells-Epithelial-B_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

CDKL2 ARMC9 AQP3 ITPR3 SLC7A1

7.84e-05197995f3ca63c7902d7530a29a85eb54f69b303031d150
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_3|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

GAD1 ZBTB16 PTPRR PDE4DIP SLITRK6

7.84e-05197995d77bc37a77546a1f0a508486a38a45e571e4645b
ToppCell356C-Epithelial_cells-Epithelial-B_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

CDKL2 ARMC9 AQP3 ITPR3 ARFGEF3

7.84e-05197995c115d0a45545ed24259ad88872231bf4d4d389d2
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_3|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

GAD1 ZBTB16 NR2F2 PTPRR PDE4DIP

7.84e-0519799562c0682eb32a41c58d31ae33b23e7d61ce5a6abb
ToppCell343B-Epithelial_cells-Epithelial-B_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

CDKL2 ARMC9 AQP3 ITPR3 SLC7A1

7.84e-05197995f98720cab066579fdac3ba24fb6fe4c5759dae4e
ToppCellFetal_29-31_weeks-Epithelial-club_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FNIP2 ARFGEF3 FAM13A PTPRR FDFT1

8.03e-051989955fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BDP1 UBR2 POU5F2 MACF1 SNRNP200

8.22e-05199995f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellmild-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BDP1 ZBTB16 AQP3 GTF3C1 MACF1

8.22e-05199995cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNIP2 CDKL2 ARMC9 ITPR3 ARFGEF3

8.22e-051999952dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

GAD1 NFASC KIFAP3 THRA PDE4DIP

8.22e-051999955de2a32bc2e9c752eb19a013b1807949153728fc
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

GAD1 NFASC KIFAP3 THRA PDE4DIP

8.22e-0519999577b4aa00f14b86ef5db0490be98787e063979541
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-Hepatocyte_(Midlobular)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFASC SH3BP4 GUF1 CYP2U1

8.25e-051039943a0f02ce52c4e2eda5b987c89317280c08f90cb3
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-BAGE2|Neuronal / cells hierarchy compared to all cells using T-Statistic

GAD1 NR2F2 PRELID2 KLHL13 MEGF11

8.41e-0520099526f07d271e984f375145e4c10528fba44a5811e1
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Interneuron|3m / Sample Type, Dataset, Time_group, and Cell type.

GAD1 ZBTB16 NR2F2 PTPRR PDE4DIP

8.41e-05200995a313b9a8bde1ea80a6eae183b76fba46b86558b4
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

GAD1 CDKL2 THRA PTPRR PDE4DIP

8.41e-05200995bad32a95b759fad509401b07bc96a56687c2a592
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-BAGE2-L1-2|Neuronal / cells hierarchy compared to all cells using T-Statistic

GAD1 NR2F2 PRELID2 KLHL13 MEGF11

8.41e-05200995c3637827ceba16b0d7956c280dd2ddbc8b1ba55e
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-MC4R|Neuronal / cells hierarchy compared to all cells using T-Statistic

GAD1 NR2F2 PRELID2 KLHL13 MEGF11

8.41e-05200995c1797542541747b524c9c22c723d24c8d027d486
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)|Neuronal / cells hierarchy compared to all cells using T-Statistic

GAD1 NR2F2 ZFHX4 PRELID2 MEGF11

8.41e-05200995d0167f96314be78b6d867bbcc6e4396071d931b8
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-dn_T|Int-URO / Disease, condition lineage and cell class

ARMC9 AQP3 PRELID2 DZIP3 PRKCQ

8.41e-05200995020439d9e70fff7246650ab0e9105236688c3ec3
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TRRAP GSPT1 STAB1 DZIP3 PTCH2

8.41e-052009950d76b006d8e8b32174e65e400acd0674354b962c
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PCSK5 ZFHX4 KLHL13 SLITRK6 VCL

8.41e-0520099508bf8c00eee6468215edb3611296bfc8784c4d56
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-CHRNA4-L1|Neuronal / cells hierarchy compared to all cells using T-Statistic

GAD1 NR2F2 PRELID2 KLHL13 MEGF11

8.41e-05200995e2ced6eb1de9a526c34c7558b9c637854916e624
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TRRAP GSPT1 STAB1 DZIP3 PTCH2

8.41e-05200995cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST|Neuronal / cells hierarchy compared to all cells using T-Statistic

GAD1 NR2F2 PRELID2 KLHL13 MEGF11

8.41e-0520099553d5e427f0cbf5cf0b63efe4ec01da302f555704
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-MC4R-L1-2|Neuronal / cells hierarchy compared to all cells using T-Statistic

GAD1 NR2F2 PRELID2 KLHL13 MEGF11

8.41e-05200995a0cc84add181109bb66ba9d49c732e1790222c96
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

GAD1 ZBTB16 NR2F2 PTPRR PDE4DIP

8.41e-05200995c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-CHRNA4|Neuronal / cells hierarchy compared to all cells using T-Statistic

GAD1 NR2F2 PRELID2 KLHL13 MEGF11

8.41e-052009959bc924755e5a4c464408e6103b86bf1b4e8c58b5
ToppCellmLN-Macrophage-Macrophage|Macrophage / Region, Cell class and subclass

UBD PLA2G2D

1.33e-048992106435b9f470979ced72c00215071e288b256922
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAM89A CHD7 SH3BP4 PRKCQ

2.21e-0413399463d2f096ae47d9b587acc6c5fbd346e5e58842b8
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Mesoderm|GW16 / Sample Type, Dataset, Time_group, and Cell type.

ZZEF1 SH3BP4 SFXN2 MEGF11

2.62e-04139994d441c29852c28928ecb696b4b95e31b30c17116b
ToppCellLymphoid-T_cells_(Cd8+_T_cell)|World / shred on cell class and cell subclass (v4)

AQP3 JAML PRELID2 PRKCQ

2.62e-04139994c85f50fb536f4df6fa4dbdebe48e1ecea1df1121
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FAM89A NFASC PRKCQ SLITRK6

3.15e-04146994a317f14a1aab11ffcce65baeb1c475c04324315f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FNIP2 GAD1 NR2F2 PRKCQ

3.32e-041489944d43efee96a6493abd78e9ca41aab73db0c80626
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|367C / Donor, Lineage, Cell class and subclass (all cells)

BDP1 LPAR5 ZZEF1 XPO6

3.41e-0414999441f28138bde45d0b814e116837e5a32b5e80d54a
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

UBR2 JAML DNAH1 XPO6

3.58e-04151994b698ddc74565d47892c09c3f16d78038da2dd5e7
ToppCellmild_COVID-19_(asymptomatic)-MAIT|World / disease group, cell group and cell class (v2)

ZBTB16 AQP3 GSPT1 GTF3C1

3.77e-041539942b4c69f6db17927d6506a645ac058133e60b0103
DrugVitexin [3681-93-4]; Up 200; 9.2uM; PC3; HT_HG-U133A

ZZEF1 ADCY9 ITPR3 SLC7A1 PTPRR PDE4DIP PTCH2 VCL

2.66e-062009984588_UP
Diseaseneutrophil count, eosinophil count

UBR2 ZBTB16 RASA2 CHD7 JAML NLRP3

7.99e-05213986EFO_0004833, EFO_0004842
Diseaseneutrophil count, basophil count

UBR2 ZBTB16 RASA2 CHD7 JAML NLRP3

1.05e-04224986EFO_0004833, EFO_0005090
Diseasemyeloid white cell count

UBR2 ZBTB16 RASA2 SH3BP1 CHD7 JAML NLRP3 GTF3C1 FAM13A XPO6 SFXN2

2.82e-049379811EFO_0007988
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

DNAH1 FAM13A FDFT1 SLC22A2 MACF1 PMFBP1

3.25e-04276986EFO_0004612, EFO_0020943
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

DNAH1 FDFT1 SLC22A2 MACF1 PMFBP1

5.55e-04200985EFO_0004611, EFO_0020945
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

DNAH1 FDFT1 SLC22A2 MACF1 PMFBP1

9.23e-04224985EFO_0004530, EFO_0008317
Diseaseserum metabolite measurement

CYP2C18 SH3BP4 AGXT2 TBC1D13 PRELID2 SLC5A6 SLC22A2 MAPKAPK3 MEGF11 PMFBP1

1.19e-039459810EFO_0005653
Diseasebody fat percentage

ZZEF1 ADCY9 EDEM3 FAM13A MACF1 SLITRK6 PMFBP1

1.23e-03488987EFO_0007800
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

DNAH1 FAM13A FDFT1 SLC22A2 MACF1

1.33e-03243985EFO_0004612, EFO_0020944
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

ZZEF1 ADCY9 EDEM3 FAM13A MACF1 PMFBP1

1.37e-03364986EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseasetriglyceride measurement, phospholipid measurement

DNAH1 FDFT1 SLC22A2 PMFBP1

1.45e-03146984EFO_0004530, EFO_0004639
DiseaseMicrocephaly

IARS1 TRRAP SLC5A6

1.46e-0367983C0025958
Diseasegranulocyte count

ZBTB16 RASA2 CHD7 JAML NLRP3

1.61e-03254985EFO_0007987
Diseaseprimary ciliary dyskinesia (implicated_via_orthology)

PCSK5 GAS2L2

1.80e-0319982DOID:9562 (implicated_via_orthology)
Diseaseadvanced glycosylation end product-specific receptor ligand measurement

FAM13A TRIM38

2.20e-0321982EFO_0010762
Diseasetriglyceride measurement, high density lipoprotein cholesterol measurement

KIF6 DNAH1 FDFT1 SLC22A2 PMFBP1

2.24e-03274985EFO_0004530, EFO_0004612
DiseasePrimary familial hypertrophic cardiomyopathy

MYH6 VCL

2.42e-0322982cv:C0949658
Diseaseurinary albumin to creatinine ratio

ZBTB16 CHD7 STAB1 EDEM3

3.04e-03179984EFO_0007778
Disease3-hydroxybutyrate measurement

FDFT1 PMFBP1

3.12e-0325982EFO_0010982
DiseaseS-6-hydroxywarfarin to S-warfarin ratio measurement

CYP2C18 SLITRK6 DNA2

3.18e-0388983EFO_0803332

Protein segments in the cluster

PeptideGeneStartEntry
LMIGIEMVQDKISCR

AGXT2

436

Q9BYV1
IEMETGLKAMGREIC

BDP1

896

A6H8Y1
GSRKDCLLMGGMVEI

GVINP1

1086

Q7Z2Y8
GREIALPIEACVMML

SH3BP1

286

Q9Y3L3
KMRGMEILGNLCKAE

ARID2

371

Q68CP9
MRNCILADEMGLGKT

CHD7

986

Q9P2D1
LVEKGLMGRMEIEAC

CDAN1

1161

Q8IWY9
GQTLMICGKEIEVMG

RAD54B

181

Q9Y620
LATRCLDEMMKIVGG

RASA2

401

Q15283
IMGIENICELAARML

NR2F2

206

P24468
LERLNKMCGVGEQMR

ITPR3

1176

Q14573
GKIMMLCEARRAVQK

GUF1

486

Q8N442
RMIDNGIGVDLVCMG

DEPDC5

356

O75140
GFKGIRCDQAALMME

MEGF11

816

A6BM72
CGINQKLMAEALAMI

PRKCQ

281

Q04759
KRCLLIIMECMEGGE

MAPKAPK3

111

Q16644
RGVLMVMVLLAGANC

LPAR5

276

Q9H1C0
LVSIAGKNVMLDCGM

INTS11

21

Q5TA45
AMGMEDILRCFIKEG

ARMC9

541

Q7Z3E5
AVMGKIALIQRGQCM

EDEM3

701

Q9BZQ6
EMVGLRQLDMSLLCQ

FAM89B

96

Q8N5H3
ICRRMGIGMAEFLDK

FDFT1

146

P37268
MMGVLLQCSAILVKE

GAD1

406

Q99259
GVCQTRAMKILMKVG

EFNB2

151

P52799
LLDLGMCQMGAICKD

PCSK5

861

Q92824
VEAENLLGLCKMEMI

POU5F2

191

Q8N7G0
LLGLCKMEMILQQSG

POU5F2

196

Q8N7G0
KKIGMREEMSLGCQE

KIF6

546

Q6ZMV9
LCIGGMSVKEQMETI

DDX41

296

Q9UJV9
GLEGMKEQDLCNKIM

FAM13A

206

O94988
DMVRMLQCDVPGIVK

DZIP3

321

Q86Y13
LESGSICKGQQLVMM

GSPT1

321

P15170
VKGRDLICIQSMDGM

BBS9

146

Q3SYG4
RVNSGCVMMENKLEG

MACF1

5111

Q9UPN3
ALSIVCQLRMDRGGM

PTPRR

616

Q15256
RQKYEMLCRGEGIKM

P4HA1

286

P13674
MDKGLLGMCVGEKRI

FKBP9

206

O95302
MGLREMCVGEKRTVI

FKBP9

431

O95302
QMVLRGMDLLLECIA

NFASC

256

O94856
GMVMKCRNKDTGRIV

CDKL2

16

Q92772
GKRVCMGEQLAKMEL

CYP2U1

486

Q7Z449
AFLLCVRIMMNEGKI

DNAH1

3526

Q9P2D7
GMKEQDLMCIKLHGV

KLHL13

126

Q9P2N7
GGLMGVIQRAMVKAC

GPAT4

271

Q86UL3
KMCGGRLSQLSIMEE

FBXL3

381

Q9UKT7
CPMEMLKIQLQDAGR

SLC25A18

121

Q9H1K4
CRKEMGIQEVLMFET

GAS2L2

121

Q8NHY3
LGAGMKMDQQAVCEL

FNIP2

671

Q9P278
ACQMLMILGLEGRSV

CUL3

186

Q13618
LIMDGMTEACIKGGI

ARFGEF3

406

Q5TH69
CCIEMGLGMIKAIEQ

ADCY9

461

O60503
LALGRCMEIMNVEAG

C1GALT1

241

Q9NS00
GKRMCMGEGLARMEL

CYP2C18

431

P33260
EMEKSGSCIGNLIRM

DNA2

471

P51530
LKIIISCLGRMGITM

SLC22A2

431

O15244
RQDCETFGMVVKMLI

PPHLN1

306

Q8NEY8
MGDPMLGERKECQKI

KIFAP3

41

Q92845
LICEGNGLKMLMKRA

KIFAP3

461

Q92845
RGLLQCMMRQVAKVE

PHKA2

86

P46019
IKGEAGQNLLEMMAC

RGPD1

326

P0DJD0
LGDLGVMMFCEVLKQ

NLRP3

981

Q96P20
ECQVKMLQGELGGIM

PMFBP1

196

Q8TBY8
CEMVMDILRERDQGG

KHSRP

296

Q92945
MKGQLACGSVREAML

CARS2

381

Q9HA77
LGVCMENVQRGTGMK

TRIM38

361

O00635
NIPMMRQQELIKGIC

SFXN2

191

Q96NB2
DGTMLINCEAKGIKM

SLITRK6

41

Q9H5Y7
QKELVMALLKMDCQG

SH3BP4

821

Q9P0V3
MALLKMDCQGLVVRL

SH3BP4

826

Q9P0V3
LCLDGGMVLMRKQVP

TEDDM1

46

Q5T9Z0
GAEGKIQMVVCIIMG

PIWIL2

661

Q8TC59
IQMVVCIIMGPRDDL

PIWIL2

666

Q8TC59
QVARNLIMKGTEMCP

PRPF6

326

O94906
VGELLMADRKMGCLP

SLC5A6

56

Q9Y289
EMVGLRQLDMSLLCQ

FAM89A

96

Q96GI7
KELMVHVGGLIQMGC

JAML

141

Q86YT9
GMIERMIEKLFPCVI

PTCH2

171

Q9Y6C5
QIDRICEMGEVMRKA

SIKE1

141

Q9BRV8
RLKGENGMEDCVMAL

IARS1

741

P41252
MDLQACIDLIEKPMG

MYH6

516

P13533
MELALLCGLVVMAGV

PLA2G2D

1

Q9UNK4
MGRQKELVSRCGEML

AQP3

1

Q92482
LLGLKGVMEMMVALC

UNC45B

416

Q8IWX7
IVTCNGKRLEDGKMM

UBD

131

O15205
DIEVLKRMGMACGLE

TFDP1

296

Q14186
MQECEMLGNEIGLPK

ZFHX4

2911

Q86UP3
QMRLAGTLCDVVIMV

ZBTB16

26

Q05516
MGCKVLLNIGQQMLR

SLC7A1

1

P30825
LCGVLRGALEMVQMA

TRAPPC3

131

O43617
ILGTCKMLGQMTDQV

VCL

321

P18206
GIRIMEMLLKEQCGA

PRELID2

171

Q8N945
LRVAVAMMDQGCREI

STAB1

376

Q9NY15
CAMLMLIREQLLEGD

TBC1D13

356

Q9NVG8
MEMALRGVRKVLCVA

TOP3A

26

Q13472
NKMIVMETCAGLVLG

TRMT6

201

Q9UJA5
GAGKTNVALMCMLRE

SNRNP200

506

O75643
KVLQGCREDMLGTMA

ZZEF1

2671

O43149
DQIILLKGCCMEIMS

THRA

246

P10827
GRLGVLAMSCINELM

XPO6

306

Q96QU8
VAMNVGKLEARMLCR

GTF3C1

391

Q12789
LKCMQGMDPITRQVG

UBR2

511

Q8IWV8
MEQGRMLLISEQGCL

ZNF425

61

Q6IV72
GVMGKNECMQGLEVI

TRRAP

3091

Q9Y4A5
MVLMEGLCSEQGRRG

PDE4DIP

1306

Q5VU43