Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF7 ZNF10 ZNF514 ZNF383 ZFP90 ZSCAN20 ZNF266 ZNF544 ZSCAN21 ZNF337 ZBTB25 ZNF665 ZNF570 ZNF358 ZNF587 ZNF483 ZNF347 ZBTB40 ZNF324 ZNF75A ZNF525 ZNF578 ZNF766 ZNF420 ZNF799 ZNF79 ZNF470 ZNF860 ZNF619 ZNF225 ZNF226 ZNF319 ZNF853 ZNF160 ZNF417 ONECUT1 RXRA ZNF774 ZNF284 ZNF287 ZNF345 ZNF646 ZNF304 ZNF445	2.89e-27	1412	89	44	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF7 ZNF10 ZNF514 ZNF383 ZFP90 ZSCAN20 ZNF266 ZNF544 ZSCAN21 ZNF337 ZBTB25 ZNF665 ZNF570 ZNF358 ZNF587 ZNF483 ZNF347 ZNF324 ZNF75A ZNF525 ZNF578 ZNF766 ZNF420 ZNF799 ZNF79 ZNF470 ZNF860 ZNF619 ZNF225 ZNF226 ZNF319 ZNF853 ZNF160 ZNF417 ONECUT1 RXRA ZNF774 ZNF284 ZNF287 ZNF345 ZNF646 ZNF304 ZNF445	1.40e-25	1459	89	43	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF7 ZNF514 ZNF383 ZSCAN20 ZNF544 ZSCAN21 ZBTB25 ZNF665 ZNF570 ZNF358 ZNF587 ZNF483 ZNF347 ZNF324 ZNF525 ZNF578 ZNF766 ZNF420 ZNF470 ZNF860 ZNF225 ZNF226 ZNF319 ZNF853 ZNF160 ZNF417 ONECUT1 RXRA ZNF774 ZNF284 ZNF287 ZNF345 ZNF646 ZNF304 ZNF445	1.06e-19	1244	89	35	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF7 ZNF514 ZNF383 ZSCAN20 ZNF544 ZSCAN21 ZBTB25 ZNF665 ZNF570 ZNF358 ZNF587 ZNF483 ZNF347 ZNF324 ZNF525 ZNF578 ZNF766 ZNF420 ZNF470 ZNF860 ZNF225 ZNF226 ZNF319 ZNF853 ZNF160 ZNF417 ONECUT1 RXRA ZNF774 ZNF284 ZNF287 ZNF345 ZNF646 ZNF304 ZNF445	2.10e-19	1271	89	35	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZNF544 ZSCAN21 ZNF358 ZNF225 ZNF226 ZNF319 ONECUT1 ZNF345 ZNF445	8.73e-04	560	89	9	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	ZNF544 ZSCAN21 ZNF358 ZNF225 ZNF226 ZNF319 ONECUT1 ZNF345 ZNF445	9.41e-04	566	89	9	GO:0001216
Domain	zf-C2H2	ZNF7 ZNF10 ZNF514 ZNF383 ZFP90 ZSCAN20 ZNF234 ZNF266 ZNF544 ZSCAN21 ZNF337 ZNF45 ZNF665 ZNF570 ZNF358 ZNF587 FIZ1 ZNF483 ZNF347 ZBTB40 ZNF324 ZNF75A ZNF525 ZNF578 ZNF766 ZNF214 ZNF420 ZNF799 ZNF79 ZNF470 ZNF860 ZNF619 ZNF225 ZNF226 ZNF235 ZNF319 ZNF853 ZNF160 ZNF417 ZNF774 ZNF284 ZNF287 ZNF345 ZNF646 ZNF304 ZNF445	9.93e-43	693	87	46	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF7 ZNF10 ZNF514 ZNF383 ZFP90 ZSCAN20 ZNF234 ZNF266 ZNF544 ZSCAN21 ZNF337 ZNF45 ZBTB25 ZNF665 ZNF570 ZNF358 ZNF587 FIZ1 ZNF483 ZNF347 ZBTB40 ZNF324 ZNF75A ZNF578 ZNF766 ZNF214 ZNF420 ZNF799 ZNF79 ZNF470 ZNF860 ZNF619 ZNF225 ZNF226 ZNF235 ZNF319 ZNF853 ZNF160 ZNF417 ZNF774 ZNF284 ZNF287 ZNF345 ZNF646 ZNF304 ZNF445	1.06e-42	694	87	46	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF7 ZNF10 ZNF514 ZNF383 ZFP90 ZSCAN20 ZNF234 ZNF266 ZNF544 ZSCAN21 ZNF337 ZNF45 ZBTB25 ZNF665 ZNF570 ZNF358 ZNF587 FIZ1 ZNF483 ZNF347 ZBTB40 ZNF324 ZNF75A ZNF525 ZNF578 ZNF766 ZNF214 ZNF420 ZNF799 ZNF79 ZNF470 ZNF860 ZNF619 ZNF225 ZNF226 ZNF235 ZNF319 ZNF853 ZNF160 ZNF417 ZNF774 ZNF284 ZNF287 ZNF345 ZNF646 ZNF304 ZNF445	5.94e-42	775	87	47	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF7 ZNF10 ZNF514 ZNF383 ZFP90 ZSCAN20 ZNF234 ZNF266 ZNF544 ZSCAN21 ZNF337 ZNF45 ZBTB25 ZNF665 ZNF570 ZNF358 ZNF587 FIZ1 ZNF483 ZNF347 ZBTB40 ZNF324 ZNF75A ZNF525 ZNF578 ZNF766 ZNF214 ZNF420 ZNF799 ZNF79 ZNF470 ZNF860 ZNF619 ZNF225 ZNF226 ZNF235 ZNF319 ZNF853 ZNF160 ZNF417 ZNF774 ZNF284 ZNF287 ZNF345 ZNF646 ZNF304 ZNF445	6.70e-42	777	87	47	PS00028
Domain	-	ZNF7 ZNF10 ZNF514 ZNF383 ZFP90 ZSCAN20 ZNF234 ZNF266 ZNF544 ZSCAN21 ZNF337 ZNF45 ZBTB25 ZNF665 ZNF570 ZNF358 ZNF587 FIZ1 ZNF483 ZNF347 ZBTB40 ZNF324 ZNF75A ZNF578 ZNF766 ZNF214 ZNF420 ZNF799 ZNF79 ZNF470 ZNF860 ZNF619 ZNF225 ZNF226 ZNF235 ZNF319 ZNF853 ZNF160 ZNF417 ZNF774 ZNF284 ZNF345 ZNF646 ZNF304 ZNF445	1.21e-41	679	87	45	3.30.160.60
Domain	Znf_C2H2	ZNF7 ZNF10 ZNF514 ZNF383 ZFP90 ZSCAN20 ZNF234 ZNF266 ZNF544 ZSCAN21 ZNF337 ZNF45 ZBTB25 ZNF665 ZNF570 ZNF358 ZNF587 FIZ1 ZNF483 ZNF347 ZBTB40 ZNF324 ZNF75A ZNF525 ZNF578 ZNF766 ZNF214 ZNF420 ZNF799 ZNF79 ZNF470 ZNF860 ZNF619 ZNF225 ZNF226 ZNF235 ZNF319 ZNF853 ZNF160 ZNF417 ZNF774 ZNF284 ZNF287 ZNF345 ZNF646 ZNF304 ZNF445	3.50e-41	805	87	47	IPR007087
Domain	ZnF_C2H2	ZNF7 ZNF10 ZNF514 ZNF383 ZFP90 ZSCAN20 ZNF234 ZNF266 ZNF544 ZSCAN21 ZNF337 ZNF45 ZBTB25 ZNF665 ZNF570 ZNF358 ZNF587 FIZ1 ZNF483 ZNF347 ZBTB40 ZNF324 ZNF75A ZNF525 ZNF578 ZNF766 ZNF214 ZNF420 ZNF799 ZNF79 ZNF470 ZNF860 ZNF619 ZNF225 ZNF226 ZNF235 ZNF319 ZNF853 ZNF160 ZNF417 ZNF774 ZNF284 ZNF287 ZNF345 ZNF646 ZNF304 ZNF445	4.16e-41	808	87	47	SM00355
Domain	Znf_C2H2-like	ZNF7 ZNF10 ZNF514 ZNF383 ZFP90 ZSCAN20 ZNF234 ZNF266 ZNF544 ZSCAN21 ZNF337 ZNF45 ZBTB25 ZNF665 ZNF570 ZNF358 ZNF587 FIZ1 ZNF483 ZNF347 ZBTB40 ZNF324 ZNF75A ZNF578 ZNF766 ZNF214 ZNF420 ZNF799 ZNF79 ZNF470 ZNF860 ZNF619 ZNF225 ZNF226 ZNF235 ZNF319 ZNF853 ZNF160 ZNF417 ZNF774 ZNF284 ZNF287 ZNF345 ZNF646 ZNF304 ZNF445	5.66e-40	796	87	46	IPR015880
Domain	KRAB	ZNF7 ZNF10 ZNF514 ZNF383 ZFP90 ZNF234 ZNF266 ZNF544 ZNF337 ZNF45 ZNF570 ZNF587 ZNF483 ZNF347 ZNF324 ZNF75A ZNF578 ZNF766 ZNF214 ZNF420 ZNF799 ZNF79 ZNF470 ZNF860 ZNF225 ZNF226 ZNF235 ZNF160 ZNF417 ZNF774 ZNF284 ZNF287 ZNF304 ZNF445	5.60e-36	358	87	34	PS50805
Domain	KRAB	ZNF7 ZNF10 ZNF514 ZNF383 ZFP90 ZSCAN20 ZNF234 ZNF266 ZNF544 ZNF337 ZNF45 ZNF570 ZNF587 ZNF483 ZNF347 ZNF324 ZNF75A ZNF578 ZNF766 ZNF214 ZNF420 ZNF799 ZNF79 ZNF470 ZNF860 ZNF225 ZNF226 ZNF235 ZNF160 ZNF417 ZNF284 ZNF287 ZNF304 ZNF445	1.60e-35	369	87	34	SM00349
Domain	KRAB	ZNF7 ZNF10 ZNF514 ZNF383 ZFP90 ZSCAN20 ZNF234 ZNF266 ZNF544 ZNF337 ZNF45 ZNF570 ZNF587 ZNF483 ZNF347 ZNF324 ZNF75A ZNF578 ZNF766 ZNF214 ZNF420 ZNF799 ZNF79 ZNF470 ZNF860 ZNF225 ZNF226 ZNF235 ZNF160 ZNF417 ZNF284 ZNF287 ZNF304 ZNF445	1.75e-35	370	87	34	IPR001909
Domain	KRAB	ZNF7 ZNF10 ZNF514 ZNF383 ZFP90 ZNF234 ZNF544 ZNF337 ZNF45 ZNF570 ZNF587 ZNF483 ZNF347 ZNF324 ZNF75A ZNF578 ZNF766 ZNF214 ZNF420 ZNF799 ZNF79 ZNF470 ZNF860 ZNF225 ZNF226 ZNF235 ZNF160 ZNF417 ZNF284 ZNF287 ZNF304 ZNF445	6.68e-33	358	87	32	PF01352
Domain	zf-C2H2_6	ZNF10 ZNF514 ZFP90 ZNF234 ZNF266 ZNF570 ZNF358 ZNF587 ZNF483 ZNF324 ZNF75A ZNF578 ZNF766 ZNF420 ZNF799 ZNF79 ZNF860 ZNF619 ZNF225 ZNF160 ZNF417 ZNF284 ZNF345 ZNF646 ZNF445	2.83e-24	314	87	25	PF13912
Domain	SCAN	ZSCAN20 ZSCAN21 ZNF483 ZNF287 ZNF445	6.19e-06	56	87	5	SM00431
Domain	SCAN_BOX	ZSCAN20 ZSCAN21 ZNF483 ZNF287 ZNF445	7.37e-06	58	87	5	PS50804
Domain	SCAN	ZSCAN20 ZSCAN21 ZNF483 ZNF287 ZNF445	7.37e-06	58	87	5	PF02023
Domain	SCAN_dom	ZSCAN20 ZSCAN21 ZNF483 ZNF287 ZNF445	7.37e-06	58	87	5	IPR003309
Domain	Retrov_capsid_C	ZSCAN20 ZSCAN21 ZNF483 ZNF287 ZNF445	8.02e-06	59	87	5	IPR008916
Domain	zf-H2C2_2	ZNF383 ZNF319 ZNF345	3.42e-05	14	87	3	PF13465
Domain	JmjC	KDM3B JMJD1C	5.54e-03	24	87	2	PF02373
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF10 GPI ZNF514 ZNF383 ZFP90 ZNF234 ZNF266 ZNF544 ZNF337 ZNF45 ZNF665 ZNF570 ZNF587 APAF1 ZNF483 ZNF347 ZNF324 ZNF75A ZNF214 ZNF420 ZNF799 ZNF79 ZNF470 ZNF860 ZNF619 ZNF225 ZNF226 ZNF235 CR1 ZNF160 ZNF417 RXRA ZNF774 ZNF287 ZNF304 ZNF445	5.37e-20	1387	65	36	M734
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	GPI ZNF383 ZFP90 ZNF45 ZNF665 ZNF483 ZNF347 ZNF324 ZNF420 ZNF799 ZNF226 ZNF235 ZNF160 RXRA ZNF284 ZNF445	2.71e-07	768	65	16	MM14851
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	GPI ZNF383 ZFP90 ZNF45 ZNF665 ZNF483 ZNF347 ZNF324 ZNF420 ZNF799 ZNF226 ZNF235 ZNF160 RXRA ZNF284 ZNF445	1.14e-05	1022	65	16	MM15436
Pathway	REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS	ZNF665 ZNF347 ZNF324 ZNF160	1.26e-04	56	65	4	MM17236
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF7 ZNF383 ZNF45 ZNF587 ZNF324 ZNF766 ZNF799 ZNF235 ZNF160 ZNF417 ZNF445	1.43e-12	181	89	11	37372979
Pubmed	Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937.	ZNF10 ZNF234 ZNF266 ZNF235 ZNF160 ZNF345	1.24e-11	21	89	6	7865130
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF7 ZNF665 ZNF347 ZNF420 ZNF160 ZNF287 ZNF445	4.45e-11	49	89	7	9630514
Pubmed	Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.	ZNF234 ZNF225 ZNF226 ZNF235 ZNF284	1.47e-09	20	89	5	12743021
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF7 ZSCAN20 ZSCAN21 ZNF665 FIZ1 ZNF347 KDM3B ZNF324 ZNF235 ZNF160 ONECUT1 RXRA ZNF646 ZNF445	1.82e-08	808	89	14	20412781
Pubmed	Detailed comparative map of human chromosome 19q and related regions of the mouse genome.	ZNF45 ZNF665 ZNF347 ZNF235 ZNF160	8.35e-07	67	89	5	8812484
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF7 ZNF10 ZSCAN20 ZNF45	1.20e-06	31	89	4	2288909
Pubmed	A GO catalogue of human DNA-binding transcription factors.	ZNF234 ZNF45 ZNF214 ZNF235	4.16e-06	42	89	4	34673265
Pubmed	Analysis of homologous XRCC1-linked zinc-finger gene families in human and mouse: evidence for orthologous genes.	ZNF45 ZNF235	6.48e-06	2	89	2	9570955
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	GPI ZFP90 LEMD3 ZNF525 ZNF420 ZNF319 KMT2E ZNF160 ZNF417 ONECUT1 JMJD1C SDF2 ZNF646	1.17e-05	1203	89	13	29180619
Pubmed	Autocrine motility factor signaling induces tumor apoptotic resistance by regulations Apaf-1 and Caspase-9 apoptosome expression.	GPI APAF1	1.94e-05	3	89	2	14566819
Pubmed	Sex-dependent regulation of hepatic CYP3A by growth hormone: Roles of HNF6, C/EBPα, and RXRα.	ONECUT1 RXRA	1.94e-05	3	89	2	25451687
Pubmed	Silencing of RNA polymerases II and III-dependent transcription by the KRAB protein domain of KOX1, a Krüppel-type zinc finger factor.	ZNF10 ZNF345	1.94e-05	3	89	2	9278146
Pubmed	HUWE1 mediates inflammasome activation and promotes host defense against bacterial infection.	HUWE1 NLRP3	1.94e-05	3	89	2	33104527
Pubmed	Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors.	IL12RB2 NLRP3	1.94e-05	3	89	2	19767732
Pubmed	Protein complex interactor analysis and differential activity of KDM3 subfamily members towards H3K9 methylation.	KDM3B JMJD1C	3.87e-05	4	89	2	23593242
Pubmed	EV-A71 induced IL-1β production in THP-1 macrophages is dependent on NLRP3, RIG-I, and TLR3.	TLR3 NLRP3	3.87e-05	4	89	2	36503883
Pubmed	SNO-MLP (S-Nitrosylation of Muscle LIM Protein) Facilitates Myocardial Hypertrophy Through TLR3 (Toll-Like Receptor 3)-Mediated RIP3 (Receptor-Interacting Protein Kinase 3) and NLRP3 (NOD-Like Receptor Pyrin Domain Containing 3) Inflammasome Activation.	TLR3 NLRP3	3.87e-05	4	89	2	31902237
Pubmed	Identification of differentially expressed genes in mouse spermatogenesis.	ZNF665 ZNF347 ZNF160	4.53e-05	27	89	3	14581517
Pubmed	A chromatin modulator sustains self-renewal and enables differentiation of postnatal neural stem and progenitor cells.	CLSTN3 SPARCL1 STAB1	6.26e-05	30	89	3	31065682
Pubmed	Chromosomal localization of 9 KOX zinc finger genes: physical linkages suggest clustering of KOX genes on chromosomes 12, 16, and 19.	ZNF10 ZNF79	6.44e-05	5	89	2	8262519
Pubmed	Computer sequence analysis of human highly conserved zinc finger modules.	ZNF7 ZNF587	9.65e-05	6	89	2	10520746
Pubmed	Leishmania RNA virus exacerbates Leishmaniasis by subverting innate immunity via TLR3-mediated NLRP3 inflammasome inhibition.	TLR3 NLRP3	1.35e-04	7	89	2	31754185
Pubmed	REV-ERBα regulates Fgf21 expression in the liver via hepatic nuclear factor 6.	ONECUT1 RXRA	1.35e-04	7	89	2	27875243
Pubmed	Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA.	TLR3 NLRP3	1.35e-04	7	89	2	17008311
Pubmed	Comparative analysis of a conserved zinc finger gene cluster on human chromosome 19q and mouse chromosome 7.	ZNF45 ZNF235	1.35e-04	7	89	2	8617494
Pubmed	The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages.	TLR3 NLRP3	1.35e-04	7	89	2	29520027
Pubmed	Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition.	APAF1 NLRP3	1.35e-04	7	89	2	33308446
Pubmed	RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway.	TLR3 NLRP3	1.79e-04	8	89	2	25326752
Pubmed	Genomic response to Wnt signalling is highly context-dependent--evidence from DNA microarray and chromatin immunoprecipitation screens of Wnt/TCF targets.	CLSTN3 TENM2	1.79e-04	8	89	2	19563800
Pubmed	Crosstalk between components of the innate immune system: promoting anti-microbial defenses and avoiding immunopathologies.	TLR3 NLRP3	2.30e-04	9	89	2	19120481
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	KDM3B KMT2E JMJD1C	2.74e-04	49	89	3	34368113
Pubmed	Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins.	ZFP90 ZNF483 ZNF525	3.09e-04	51	89	3	11853319
Pubmed	Bacterial RNA mediates activation of caspase-1 and IL-1β release independently of TLRs 3, 7, 9 and TRIF but is dependent on UNC93B.	TLR3 NLRP3	3.51e-04	11	89	2	22634614
Pubmed	In vivo IFN-γ secretion by NK cells in response to Salmonella typhimurium requires NLRC4 inflammasomes.	TLR3 NLRP3	4.20e-04	12	89	2	24827856
Pubmed	MyD88-dependent signaling contributes to host defense against ehrlichial infection.	TLR3 NLRP3	4.20e-04	12	89	2	20668698
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	ZFP90 ZSCAN21 ZNF358 ZNF226 ZNF235 ONECUT1 RXRA ZNF445	4.75e-04	709	89	8	22988430
Pubmed	Macrophage-derived IL-1α promotes sterile inflammation in a mouse model of acetaminophen hepatotoxicity.	TLR3 NLRP3	4.96e-04	13	89	2	28504245
Pubmed	Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction.	ZNF665 ZNF347 ZNF160	4.99e-04	60	89	3	18023262
Pubmed	Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population.	AMT MAPKAPK3 STAB1	5.49e-04	62	89	3	19367581
Pubmed	Rubella vaccine-induced cellular immunity: evidence of associations with polymorphisms in the Toll-like, vitamin A and D receptors, and innate immune response genes.	TLR3 RXRA	5.78e-04	14	89	2	19902255
Pubmed	Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection.	TLR3 NLRP3	5.78e-04	14	89	2	30510167
Pubmed	Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering.	ZNF10 ZSCAN21	5.78e-04	14	89	2	2014798
Pubmed	Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.	TLR3 NLRP3	5.78e-04	14	89	2	19570822
Pubmed	Neutrophils Directly Recognize Group B Streptococci and Contribute to Interleukin-1β Production during Infection.	TLR3 NLRP3	6.65e-04	15	89	2	27509078
Pubmed	Armc5 deletion causes developmental defects and compromises T-cell immune responses.	ZBTB40 HUWE1	8.59e-04	17	89	2	28169274
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ZSCAN21 ZNF570 ZNF483 ZBTB40 KDM3B ZNF226 JMJD1C	9.64e-04	608	89	7	36089195
Pubmed	Gata3 is a critical regulator of cochlear wiring.	SPARCL1 ONECUT1	9.65e-04	18	89	2	23426694
Pubmed	DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88.	TLR3 NLRP3	9.65e-04	18	89	2	22541070
Pubmed	Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.	JMJD1C RXRA	9.65e-04	18	89	2	7776974
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	GPI ZSCAN20 ZSCAN21 ZNF766 ZNF235 ZNF319	1.08e-03	451	89	6	36168627
Pubmed	Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.	ZNF7 ZFP90	1.19e-03	20	89	2	7479878
Pubmed	Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.	ZNF7 ZFP90	1.19e-03	20	89	2	2542606
Pubmed	Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.	ZNF45 ZNF483 ZNF324	1.28e-03	83	89	3	20562864
Pubmed	Chromosomal localization of the genes for five zinc finger proteins expressed in mouse lens.	GPI ZNF226	1.45e-03	22	89	2	7590745
Pubmed	Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor.	TLR3 NLRP3	1.72e-03	24	89	2	34526512
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	ZBTB40 ZNF619 KMT2E ZNF160 ZNF417 JMJD1C	1.77e-03	497	89	6	23414517
Interaction	TRIM28 interactions	ZNF7 ZNF10 ZNF514 ZNF383 ZFP90 SPG7 WDHD1 ZNF544 ZNF45 ZNF587 APAF1 ZNF483 ZNF324 ZNF766 ZNF420 ZNF799 ZNF226 HUWE1 ZNF235 ZNF160 ZNF417 NLRP3 ZNF284 ZNF287 ZNF304 ZNF445	1.76e-10	1474	85	26	int:TRIM28
Interaction	LTBP2 interactions	ZSCAN21 ZNF358 ZNF483 ZNF324 ZNF766 ZNF417 ZNF646	6.99e-08	85	85	7	int:LTBP2
Interaction	NOTCH2 interactions	ZNF7 ZSCAN21 ZNF358 FIZ1 ZNF483 ZNF324 ZNF766 ZNF235 ZNF417 ZNF646 ZNF445	1.62e-06	423	85	11	int:NOTCH2
Interaction	KRTAP10-7 interactions	ZNF266 SPG7 ZSCAN21 ZNF337 ZNF587 ZNF578 ZNF420 ZNF417 ZNF774	4.02e-06	293	85	9	int:KRTAP10-7
Interaction	KRTAP10-9 interactions	SPG7 ZSCAN21 ZNF587 ZNF578 ZNF860 ZNF319 ZNF417 ZNF774	8.11e-06	241	85	8	int:KRTAP10-9
Interaction	ZNF232 interactions	ZSCAN20 ZSCAN21 ZNF483 ZNF445	6.84e-05	52	85	4	int:ZNF232
Interaction	ZNF445 interactions	ZSCAN20 ZNF483 ZNF287 ZNF445	9.82e-05	57	85	4	int:ZNF445
Interaction	BEGAIN interactions	ZNF587 ZNF319 ZNF417 ZNF774	1.12e-04	59	85	4	int:BEGAIN
Interaction	ZNF396 interactions	ZSCAN20 ZSCAN21 ZNF445	1.21e-04	23	85	3	int:ZNF396
Interaction	VWC2 interactions	ZNF587 ZNF319 ZNF417 ZNF774	1.36e-04	62	85	4	int:VWC2
Interaction	VWCE interactions	ZSCAN21 ZNF358 FIZ1 ZNF324	1.54e-04	64	85	4	int:VWCE
Interaction	EFEMP1 interactions	DDIAS ZSCAN21 ZNF358 ZNF324 ZNF646	1.73e-04	123	85	5	int:EFEMP1
Interaction	FBLN2 interactions	ZSCAN21 ZNF358 ZNF324 ZNF235	1.74e-04	66	85	4	int:FBLN2
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	GPI ZNF383 ZNF234 ZNF544 ZNF45 ZNF665 ZNF570 ZNF587 FIZ1 ZNF347 ZNF324 ZNF525 ZNF578 ZNF766 ZNF420 ZNF470 ZNF225 ZNF226 ZNF235 ZNF160 ZNF417 ZNF284 ZNF345 ZNF304	4.54e-18	1192	89	24	chr19q13
Cytoband	19q13.43	ZNF544 ZNF587 ZNF324 ZNF470 ZNF417	7.97e-07	87	89	5	19q13.43
Cytoband	19q13.42	ZNF665 FIZ1 ZNF347 ZNF525 ZNF160	4.77e-06	125	89	5	19q13.42
Cytoband	19q13.12	ZNF383 ZNF570 ZNF420 ZNF345	1.23e-05	72	89	4	19q13.12
Cytoband	19q13.2	ZNF45 ZNF225 ZNF226 ZNF235	3.03e-04	164	89	4	19q13.2
Cytoband	19q13.31	ZNF234 ZNF284	1.46e-03	29	89	2	19q13.31
Cytoband	Ensembl 112 genes in cytogenetic band chr3p21	AMT MAPKAPK3 STAB1 ZNF445	3.40e-03	316	89	4	chr3p21
Cytoband	1q32	CACNA1S CR1	4.12e-03	49	89	2	1q32
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF7 ZNF10 ZNF514 ZNF383 ZFP90 ZSCAN20 ZNF234 ZNF266 ZNF544 ZSCAN21 ZNF337 ZNF45 ZBTB25 ZNF665 ZNF570 ZNF358 ZNF587 FIZ1 ZNF483 ZNF347 ZBTB40 ZNF324 ZNF75A ZNF525 ZNF578 ZNF766 ZNF214 ZNF420 ZNF799 ZNF79 ZNF470 ZNF860 ZNF619 ZNF225 ZNF226 ZNF235 ZNF319 ZNF853 ZNF160 ZNF417 ZNF774 ZNF284 ZNF287 ZNF345 ZNF646 ZNF304 ZNF445	5.41e-46	718	78	47	28
Coexpression	NIKOLSKY_BREAST_CANCER_19Q13.1_AMPLICON	ZNF383 ZNF570 ZNF420 ZNF345	7.91e-07	22	87	4	M8692
Coexpression	ZWANG_DOWN_BY_2ND_EGF_PULSE	GAS2L3 ZNF587 ZNF483 ZNF79 ZNF470 ZNF225 ZNF287 ZNF646	1.17e-05	321	87	8	M2615
Coexpression	GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_UP	ZNF7 ZNF324 ZNF766 ZNF420 ZNF319 ZNF646	4.28e-05	191	87	6	M4702
Coexpression	GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_UP	DDIAS ZSCAN21 ZNF570 APAF1 ZNF420 ZNF304	5.23e-05	198	87	6	M4291
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_UP	AMT MANBA SPG7 ZBTB25 ZBTB40 RXRA	5.53e-05	200	87	6	M4524
ToppCell	control-Myeloid-Non-resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KDM3B CR1 JMJD1C RXRA SLC25A37 STAB1	2.81e-06	197	89	6	df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CDO1 KCTD3 ZNF578 ZNF853 KIF7 ZNF445	3.06e-06	200	89	6	36de49593cf6ff1c9229fcceb150c1d68658a360
ToppCell	COVID-CD8-memory_CD4\|COVID / Condition, Cell_class and T cell subcluster	ZNF10 ZNF514 ZNF324 ZNF578 ZNF470	1.85e-05	162	89	5	22b2a32217d357146c117e618813d451510a1801
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|356C / Donor, Lineage, Cell class and subclass (all cells)	ZNF10 AMT ZFP90 ZNF45 ZNF570	2.08e-05	166	89	5	c4f7ea1cad962b1d6ad77423d15978b68a0d6f1d
ToppCell	E16.5-Endothelial-Endothelial_lymphatic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AMT TLR3 ZNF235 RXRA STAB1	2.14e-05	167	89	5	b93103a868fba63a8910bffb690a6242b9252833
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AMT TLR3 ZNF235 RXRA STAB1	2.14e-05	167	89	5	fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AMT TLR3 ZNF235 RXRA STAB1	2.14e-05	167	89	5	f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AMT TLR3 ZNF235 RXRA STAB1	2.14e-05	167	89	5	26cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCell	5'-Adult-LymphNode-Epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL12RB2 PARP16 ZNF665 ZNF347 ZNF345	3.07e-05	180	89	5	cc974ac352ef2adc953fb5f325880e5857595889
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5\|TCGA-Liver / Sample_Type by Project: Shred V9	DDIAS ZSCAN20 WDHD1 GAS2L3 POLQ	3.32e-05	183	89	5	f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell	Control-Myeloid-Monocyte-derived_macrophages\|Control / group, cell type (main and fine annotations)	MANBA GAS2L3 CR1 NLRP3 STAB1	4.27e-05	193	89	5	a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CR1 JMJD1C RXRA SLC25A37 STAB1	4.83e-05	198	89	5	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	3'_v3-bone_marrow-Myeloid_Monocytic\|bone_marrow / Manually curated celltypes from each tissue	CR1 RXRA SLC25A37 NLRP3 STAB1	4.94e-05	199	89	5	51a766f823a9d50a3b1d59d0df2f5241a6b44c2b
ToppCell	3'_v3-bone_marrow-Myeloid_Monocytic-Classical_monocytes\|bone_marrow / Manually curated celltypes from each tissue	CR1 RXRA SLC25A37 NLRP3 STAB1	4.94e-05	199	89	5	93f25e8f22deb438c930c2e95e572dbd16503f71
ToppCell	control-HLA-DR-_S100A+_Monocyte\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	APAF1 CR1 RXRA NLRP3 STAB1	5.06e-05	200	89	5	9e3e13a68bc1110fa000ec2d80f4c654ddbce17e
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CDO1 KCTD3 ZNF578 ZNF853 KIF7	5.06e-05	200	89	5	4c3c11dd5e71ebc3d62264eeaeb71a850b149779
Disease	fetuin-B measurement	HRG JMJD1C	3.38e-04	10	82	2	EFO_0008128
Disease	gastrin-releasing peptide measurement	HRG JMJD1C	4.13e-04	11	82	2	EFO_0022000
Disease	diet measurement	ZFP90 MIER3 KDM3B ZNF420 MBD5 ONECUT1 TENM2 JMJD1C ZNF287 ZNF345	6.51e-04	1049	82	10	EFO_0008111
Disease	semaphorin-3A measurement	GPI HRG	7.82e-04	15	82	2	EFO_0008278
Disease	venous thromboembolism, fibrinogen measurement	ZNF160 JMJD1C NLRP3	8.72e-04	67	82	3	EFO_0004286, EFO_0004623
Disease	partial thromboplastin time	HRG ZNF160	2.02e-03	24	82	2	EFO_0004310
Disease	alpha fetoprotein measurement	MANBA POLQ JMJD1C	2.76e-03	100	82	3	EFO_0010583

Protein segments in the cluster

Peptide	Gene	Start	Entry
QTSHHRAAGLQSQHA	nan	106	Q9HAA7
HFTNSSHHLLLATGS	APAF1	706	O14727
SHVLSSQQFLHRGHQ	CLSTN3	811	Q9BQT9
LQHPSGVRQHAFSSH	OTUD4	381	Q01804
SLRINHANHTGSNHT	LEMD3	421	Q9Y2U8
GAQRHSHNNNSSDLH	HRG	336	P04196
GTAIQFLHSHNIAHR	MAPKAPK3	151	Q16644
ESAHASSLSHLALAH	JMJD1C	816	Q15652
RINFHHGHSLNSQVT	IL12RB2	76	Q99665
HSSHHEIGVNDSNLF	DDIAS	326	Q8IXT1
HHHQRLAGNVSGSFT	ONECUT1	136	Q9UBC0
AARHTGATHLNHLSS	KIF7	201	Q2M1P5
GATHLNHLSSRSHTV	KIF7	206	Q2M1P5
LTQEFRHLSNTHTNH	KDM3B	1716	Q7LBC6
VLASGHHTTSAQALH	KMT2E	1726	Q8IZD2
RFNHFSLTLNTNHGH	GPI	36	P06744
ETNGFISAHALHQHA	MIER3	531	Q7Z3K6
LLFTHIRLAHGFSNH	HUWE1	256	Q7Z6Z7
FHGSRLENFHSIIHN	PARP16	151	Q8N5Y8
ILHGEHTLSHQDNFS	CR1	1656	P17927
GNSNHSNSHVFSSVH	CACNA1S	1671	Q13698
HGSSIHDHTNSHCFL	CDO1	81	Q16878
HNHISSRDNAVSHLA	GAS2L3	476	Q86XJ1
QLETFHSTFKSHGHR	POLQ	2491	O75417
SFNSKFSLHRQHHEG	MANBA	576	O00462
KHSFNLANHLRSHTG	FIZ1	61	Q96SL8
HALHFPSNSTSNNHL	MBD5	896	Q9P267
TDSHLHTRQHCSLFD	AMT	66	P48728
LATGLHVHRNSAHSA	RXRA	326	P19793
SHLRESNSSLQLQHH	KCTD3	621	Q9Y597
SSHAACSHGLVNSHL	NLRP3	711	Q96P20
RHHNAHFGSDLVRAS	SYTL1	91	Q8IYJ3
TLNDVFHHQGNSHLA	SLC25A37	131	Q9NYZ2
HHPRSFNLNTNSLHS	TEX53	31	A0A1B0GU33
SHHHSSANSLNRNSL	TENM2	261	Q9NT68
HAAREGHTSVHTLNF	SPG7	531	Q9UQ90
HVNTGRNLHSHHFTS	SDF2	96	Q99470
RNLHSHHFTSPLSGN	SDF2	101	Q99470
GVSHHQSHLFHTVSR	CHST9	191	Q7L1S5
SNLRQHLHTHVSGSL	ZBTB25	251	P24278
VFTQNSHLASHRGIH	ZNF665	466	Q9H7R5
GSSFHSHLSELHIFQ	ZNF525	141	Q8N782
RGHSNLTTHQLIHTG	ZNF160	351	Q9HCG1
FTQNSHLANHQRTHT	ZNF160	686	Q9HCG1
QHLFSHSLHGLFNVR	TLR3	311	O15455
HSSNLTQHQLLHTGE	ZNF324	436	O75467
AFSSGSALTNHQRIH	ZNF383	346	Q8NA42
CGKTFNVQSHLSRHH	ZNF578	516	Q96N58
SFSQHAGLSSHQRLH	ZSCAN21	396	Q9Y5A6
FSQSANLTQHHRTHT	ZNF287	601	Q9HBT7
SDHSNLITHQRIHTG	ZSCAN20	776	P17040
VFQRGSLLSQFSHHH	SLC37A3	6	Q8NCC5
HHATHLSNTLNYTIA	WDHD1	476	O75717
SHHQLNRSSKHSQGL	SPARCL1	171	Q14515
SFNQSSHFITHQRIH	ZNF774	411	Q6NX45
NQRSHFLTHQRTHTG	ZNF774	441	Q6NX45
TFQRSSTLLHHQSSH	ZNF587	556	Q96SQ5
AFGHTSSLIKHQRTH	ZNF514	296	Q96K75
TFQRSSTLLHHQSSH	ZNF417	556	Q8TAU3
GSLINHRQSHQTGHF	ZNF646	1216	O15015
SHQELASHLQAHARG	ZNF646	1596	O15015
SYHNSLQTHERLHTG	ZNF799	151	Q96GE5
SQSAHLAQHQRIHTG	ZNF470	266	Q6ECI4
QGNSSHLDADTVRHH	STAB1	1176	Q9NY15
FSQASHLLTHQRVHS	ZNF234	521	Q14588
FTQNSHLARHRGIHT	ZNF347	746	Q96SE7
SVGHQSLHRDTFHFL	ZNF225	46	Q9UK10
TENSQLHSHQRVHTG	ZNF225	606	Q9UK10
SRNSHLQSHQRVHTG	ZNF226	401	Q9NYT6
SFSRSSHLIGHQKTH	ZNF10	301	P21506
GFSQHSNLVTHQRIH	ZNF853	521	P0CG23
FSLLTSLAQHHSSHS	ZNF319	141	Q9P2F9
FASFFLSQLLGHHHS	UBE3B	796	Q7Z3V4
LQHARASSHIFLHGD	TRIM51G	291	A0A3B3IT33
FSLSSHHQRGQSLHT	ZNF445	466	P59923
HHQRGQSLHTVGVSF	ZNF445	471	P59923
SQNSHLAQHQRIHTG	ZNF570	396	Q96NI8
GSSNLLSHHRIHSGE	ZNF544	671	Q6NX49
SFSQSSSLNEHHRIH	ZNF483	671	Q8TF39
SHGSQLTQHQRIHTG	ZNF420	401	Q8TAQ5
AFTQSSHLSQHQRLH	ZNF420	511	Q8TAQ5
FSHGSQLTLHQRIHT	ZNF420	596	Q8TAQ5
SHNSSLILHQRVHTG	ZNF304	541	Q9HCX3
NQQSNLASHHRLHTG	ZNF860	296	A6NHJ4
TQNSHLANHQRIHTG	ZNF766	421	Q5HY98
AFGSGSNLTHHQRIH	ZNF345	126	Q14585
FSSGSDLTQHHRIHT	ZNF345	351	Q14585
FSQNTNLHTHQRTHT	ZNF75A	226	Q96N20
HRSSVFLQHQRFHTG	ZNF619	366	Q8N2I2
HSANLTNHQRTHTGE	ZNF79	316	Q15937
GFSQASHFHTHQRVH	ZNF235	691	Q14590
SNQSSHLQVHRVHTG	ZNF45	146	Q02386
SFSQISSLHNHQRVH	ZNF214	311	Q9UL59
GQSSSLIHHQRIHTG	ZNF7	316	P17097
SVGHQLSHRDTFHFQ	ZNF284	46	Q2VY69
RQANGLSIHLHTFHN	ZBTB40	931	Q9NUA8
FRHSSSLGQHENAHT	ZFP90	291	Q8TF47
GFSNKSHLITHQRTH	ZNF337	356	Q9Y3M9
FGQSSALLQHLHVHS	ZNF358	356	Q9NW07
SGKSFINHSHLQGHL	ZNF266	161	Q14584