Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionactin filament binding

MYH11 PPP1R9A SPTBN1 HIP1R AIF1L ACTR3B SPTBN4 SPTBN5 GAS2L1 MYO1F PPP1R9B PLEC

1.63e-0722715112GO:0051015
GeneOntologyMolecularFunctioncytoskeletal protein binding

MYH11 OFD1 CLIP2 STXBP5 PPP1R9A SPTBN1 HIP1R AIF1L ACTR3B SHANK3 SPTBN4 SPTBN5 CCDC88C GAS2L1 HAUS8 BRCA1 NFKB1 MARK4 MYO1F GOLGA8B PPP1R9B PLEC MARK2 TRIM36 CDK5

7.47e-07109915125GO:0008092
GeneOntologyMolecularFunctionactin binding

MYH11 PPP1R9A SPTBN1 HIP1R AIF1L ACTR3B SHANK3 SPTBN4 SPTBN5 GAS2L1 MYO1F PPP1R9B PLEC

7.34e-0547915113GO:0003779
GeneOntologyMolecularFunctionRoundabout binding

RTN4R SLIT2 SLIT3

8.87e-05121513GO:0048495
GeneOntologyMolecularFunctionganglioside GM1 binding

RTN4R EPDR1

1.70e-0431512GO:1905573
GeneOntologyMolecularFunctionanandamide 8,9 epoxidase activity

CYP2D7 CYP2D6

3.37e-0441512GO:0062187
GeneOntologyMolecularFunctionanandamide 11,12 epoxidase activity

CYP2D7 CYP2D6

3.37e-0441512GO:0062188
GeneOntologyMolecularFunctionsteroid 21-monooxygenase activity

CYP2D7 CYP2D6

3.37e-0441512GO:0004509
GeneOntologyMolecularFunctionprogesterone 21-hydroxylase activity

CYP2D7 CYP2D6

3.37e-0441512GO:0106309
GeneOntologyMolecularFunctionglucokinase activity

HK1 HKDC1

5.60e-0451512GO:0004340
GeneOntologyMolecularFunctionNAD transmembrane transporter activity

SLC25A51 SLC25A52

5.60e-0451512GO:0051724
GeneOntologyMolecularFunctionhexokinase activity

HK1 HKDC1

5.60e-0451512GO:0004396
GeneOntologyMolecularFunctionfructokinase activity

HK1 HKDC1

5.60e-0451512GO:0008865
GeneOntologyMolecularFunctionganglioside binding

RTN4R EPDR1

5.60e-0451512GO:0035594
GeneOntologyMolecularFunctiontau-protein kinase activity

MARK4 MARK2 CDK5

5.87e-04221513GO:0050321
GeneOntologyMolecularFunctionankyrin binding

SPTBN1 SPTBN4 PLEC

6.72e-04231513GO:0030506
GeneOntologyMolecularFunctioncytoskeletal anchor activity

SPTBN4 GAS2L1 MARK4

7.64e-04241513GO:0008093
GeneOntologyMolecularFunctionanandamide 14,15 epoxidase activity

CYP2D7 CYP2D6

8.35e-0461512GO:0062189
GeneOntologyMolecularFunctionanandamide epoxidase activity

CYP2D7 CYP2D6

8.35e-0461512GO:0062186
GeneOntologyMolecularFunctionadenine nucleotide transmembrane transporter activity

SLC35B3 SLC25A51 SLC25A52

9.70e-04261513GO:0000295
GeneOntologyMolecularFunctionpurine nucleotide transmembrane transporter activity

SLC35B3 SLC25A51 SLC25A52

1.34e-03291513GO:0015216
GeneOntologyMolecularFunctiontubulin binding

OFD1 CLIP2 CCDC88C GAS2L1 HAUS8 BRCA1 MARK4 GOLGA8B TRIM36 CDK5

1.58e-0342815110GO:0015631
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DENND2A ARHGAP24 STXBP5 ITSN1 TBC1D2B CCDC88C SLIT2 RGL1 RGS6 RALBP1 WDR41

1.67e-0350715111GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

DENND2A ARHGAP24 STXBP5 ITSN1 TBC1D2B CCDC88C SLIT2 RGL1 RGS6 RALBP1 WDR41

1.67e-0350715111GO:0030695
GeneOntologyMolecularFunctionnucleotide transmembrane transporter activity

SLC35B3 SLC25A51 SLC25A52

1.96e-03331513GO:0015215
GeneOntologyMolecularFunctiondinucleotide phosphatase activity

CILP NUDT13

1.98e-0391512GO:0004551
GeneOntologyMolecularFunctionprotein phosphatase 1 binding

PPP1R9A SH3RF2 PPP1R9B

2.32e-03351513GO:0008157
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

CACNA1A SEMA3F NPR2 STXBP5 USP9X RTN4R PPP1R9A LAMB3 SPG11 TENM2 SHANK3 SPTBN4 SLIT2 LHX2 NRXN3 SKOR2 ANAPC2 SLIT3 GOLGA8B ULK1 MARK2 CDK5

2.81e-0874815122GO:0048667
GeneOntologyBiologicalProcessaxonogenesis

CACNA1A SEMA3F NPR2 STXBP5 USP9X RTN4R LAMB3 SPG11 TENM2 SPTBN4 SLIT2 LHX2 NRXN3 ANAPC2 SLIT3 GOLGA8B ULK1 MARK2 CDK5

3.48e-0856615119GO:0007409
GeneOntologyBiologicalProcessaxon development

CACNA1A SEMA3F NPR2 STXBP5 USP9X RTN4R LAMB3 SPG11 TENM2 XYLT1 SPTBN4 SLIT2 LHX2 NRXN3 ANAPC2 SLIT3 GOLGA8B ULK1 MARK2 CDK5

5.04e-0864215120GO:0061564
GeneOntologyBiologicalProcessaxon extension

SEMA3F USP9X RTN4R SPG11 SLIT2 LHX2 ANAPC2 SLIT3 ULK1 CDK5

5.91e-0813515110GO:0048675
GeneOntologyBiologicalProcessneuron projection morphogenesis

CACNA1A SEMA3F NPR2 STXBP5 USP9X RTN4R PPP1R9A LAMB3 SPG11 TENM2 SHANK3 SPTBN4 SLIT2 LHX2 NRXN3 SKOR2 ANAPC2 SLIT3 GOLGA8B ULK1 MARK2 CDK5

9.55e-0880215122GO:0048812
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

CACNA1A SEMA3F NPR2 STXBP5 USP9X RTN4R PPP1R9A LAMB3 SPG11 TENM2 SHANK3 SPTBN4 SLIT2 LHX2 NRXN3 SKOR2 ANAPC2 SLIT3 GOLGA8B ULK1 MARK2 CDK5

1.37e-0781915122GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

CACNA1A SEMA3F NPR2 STXBP5 USP9X RTN4R PPP1R9A LAMB3 SPG11 TENM2 SHANK3 SPTBN4 SLIT2 LHX2 NRXN3 SKOR2 ANAPC2 SLIT3 GOLGA8B ULK1 MARK2 CDK5

1.59e-0782615122GO:0048858
GeneOntologyBiologicalProcesscell morphogenesis

CACNA1A SEMA3F NPR2 STXBP5 USP9X RTN4R PPP1R9A LAMB3 SPG11 TENM2 SHANK3 SPTBN4 CCDC88C SLIT2 LHX2 TFCP2L1 NRXN3 SH3D19 SKOR2 ANAPC2 SLIT3 GOLGA8B ULK1 PLEC MARK2 CDK5

5.40e-07119415126GO:0000902
GeneOntologyBiologicalProcesspostsynapse organization

SEMA3F USP9X ITSN1 RTN4R PPP1R9A UBE3B HIP1R SHANK3 NRXN3 LRRTM4 PPP1R9B MARK2 CDK5

5.43e-0731315113GO:0099173
GeneOntologyBiologicalProcesssynapse organization

CACNA1A SEMA3F USP9X ITSN1 RTN4R PPP1R9A UBE3B HIP1R SPG11 LRRTM3 SHANK3 SPTBN4 SLIT2 NRXN3 ANAPC2 LRRTM4 PPP1R9B MARK2 CDK5

6.58e-0768515119GO:0050808
GeneOntologyBiologicalProcessregulation of synapse organization

SEMA3F USP9X ITSN1 RTN4R PPP1R9A UBE3B LRRTM3 SHANK3 SLIT2 ANAPC2 LRRTM4 PPP1R9B MARK2 CDK5

1.02e-0638715114GO:0050807
GeneOntologyBiologicalProcessregulation of postsynapse organization

SEMA3F USP9X ITSN1 RTN4R PPP1R9A UBE3B SHANK3 PPP1R9B MARK2 CDK5

1.11e-0618515110GO:0099175
GeneOntologyBiologicalProcessregulation of synapse structure or activity

SEMA3F USP9X ITSN1 RTN4R PPP1R9A UBE3B LRRTM3 SHANK3 SLIT2 ANAPC2 LRRTM4 PPP1R9B MARK2 CDK5

1.30e-0639515114GO:0050803
GeneOntologyBiologicalProcessnegative regulation of cytoskeleton organization

PPP1R9A SPTBN1 HIP1R SHANK3 SPTBN4 SPTBN5 CCDC88C SLIT2 GAS2L1 BRCA1

1.71e-0619415110GO:0051494
GeneOntologyBiologicalProcessneuron projection development

CACNA1A SEMA3F NPR2 STXBP5 USP9X ITSN1 RTN4R PPP1R9A LAMB3 SPG11 TENM2 SHANK3 XYLT1 SPTBN4 SLIT2 LHX2 NRXN3 SKOR2 ANAPC2 SLIT3 GOLGA8B PPP1R9B ATXN10 ULK1 MARK2 CDK5

2.13e-06128515126GO:0031175
GeneOntologyBiologicalProcesssynapse assembly

CACNA1A USP9X RTN4R PPP1R9A UBE3B LRRTM3 SHANK3 SLIT2 NRXN3 LRRTM4 PPP1R9B CDK5

2.93e-0630815112GO:0007416
GeneOntologyBiologicalProcessneuron projection extension

SEMA3F USP9X RTN4R SPG11 SLIT2 LHX2 ANAPC2 SLIT3 ULK1 CDK5

3.06e-0620715110GO:1990138
GeneOntologyBiologicalProcessregulation of organelle organization

NPR2 PPP1R9A SPTBN1 HDAC8 TBC1D2B HIP1R SHANK3 SPDL1 SPTBN4 SPTBN5 CHMP7 CCDC88C SLIT2 GAS2L1 HAUS8 BRCA1 RALBP1 ARID2 ANAPC2 MARK4 PKD1 MYO1F ULK1 MARK2 TRIM36 KNL1

4.68e-06134215126GO:0033043
GeneOntologyBiologicalProcessregulation of cytoskeleton organization

PPP1R9A SPTBN1 HIP1R SHANK3 SPTBN4 SPTBN5 CHMP7 CCDC88C SLIT2 GAS2L1 HAUS8 BRCA1 PKD1 MYO1F MARK2 TRIM36

5.60e-0657915116GO:0051493
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

ARHGAP24 STXBP5 USP9X RTN4R PPP1R9A UBE3B SPTBN1 TBC1D2B HIP1R LRRTM3 TENM2 SHANK3 SPTBN4 SPTBN5 CHMP7 SLIT2 HAUS8 TRIM11 BRCA1 LRRTM4 MARK4 PPP1R9B ULK1 PLD1

5.77e-06118915124GO:0044087
GeneOntologyBiologicalProcessprotein localization to cytoskeleton

GAS2L1 MARK4 SNX10 PPP1R9B PIBF1 GOLGB1

6.71e-06631516GO:0044380
GeneOntologyBiologicalProcessorganelle assembly

MYH11 OFD1 USP9X MTERF3 TBC1D2B SPG11 SHANK3 CHMP7 HAUS8 NRXN3 BRCA1 MARK4 SNX10 GOLGA8B ATXN10 ULK1 PLEC PIBF1 HYDIN CCDC136 VPS37D CFAP46 KNL1

9.08e-06113815123GO:0070925
GeneOntologyBiologicalProcessregulation of axonogenesis

CACNA1A SEMA3F RTN4R SLIT2 ANAPC2 GOLGA8B ULK1 MARK2 CDK5

1.23e-051921519GO:0050770
GeneOntologyBiologicalProcessdevelopmental growth involved in morphogenesis

SEMA3F NPR2 USP9X RTN4R SPG11 SLIT2 LHX2 ANAPC2 SLIT3 ULK1 CDK5

1.32e-0529915111GO:0060560
GeneOntologyBiologicalProcessdevelopmental cell growth

SEMA3F NPR2 USP9X RTN4R SPG11 SLIT2 LHX2 ANAPC2 SLIT3 ULK1 CDK5

1.40e-0530115111GO:0048588
GeneOntologyBiologicalProcessnegative regulation of supramolecular fiber organization

PPP1R9A SPTBN1 HIP1R SHANK3 SPTBN4 SPTBN5 CCDC88C SLIT2 GAS2L1

1.51e-051971519GO:1902904
GeneOntologyBiologicalProcessnegative regulation of cellular component organization

SEMA3F ARHGAP24 RTN4R PPP1R9A SPTBN1 HIP1R SHANK3 SPDL1 XYLT1 SPTBN4 SPTBN5 CCDC88C SLIT2 GAS2L1 TRIM11 BRCA1 ULK1 KNL1 CDK5

1.87e-0586415119GO:0051129
GeneOntologyBiologicalProcessneuron development

CACNA1A SEMA3F NPR2 STXBP5 USP9X ITSN1 RTN4R PPP1R9A LAMB3 SPG11 TENM2 SHANK3 XYLT1 SPTBN4 SLIT2 LHX2 NRXN3 SKOR2 ANAPC2 SLIT3 GOLGA8B PPP1R9B ATXN10 ULK1 MARK2 CDK5

2.14e-05146315126GO:0048666
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

OFD1 CLIP2 SPDL1 CHMP7 CCDC88C GAS2L1 HAUS8 BRCA1 MARK4 PKD1 GOLGA8B MARK2 PIBF1 TRIM36 HYDIN CFAP46 CDK5

2.18e-0572015117GO:0000226
GeneOntologyBiologicalProcesscerebellar cortex morphogenesis

CACNA1A USP9X SKOR2 ULK1 CDK5

2.61e-05481515GO:0021696
GeneOntologyBiologicalProcesscell junction organization

CACNA1A SEMA3F USP9X ITSN1 RTN4R PPP1R9A UBE3B HIP1R SPG11 LRRTM3 SHANK3 SPTBN4 SLIT2 NRXN3 ANAPC2 LRRTM4 PPP1R9B PLEC MARK2 CDK5

2.96e-0597415120GO:0034330
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

ARHGAP24 OFD1 USP9X PPP1R9A TBC1D2B AIF1L TENM2 SLIT2 MARK4 SNX10 PPP1R9B ATXN10 PLD1 PIBF1 HYDIN CFAP46

3.37e-0567015116GO:0120031
GeneOntologyBiologicalProcessnegative regulation of neurogenesis

SEMA3F RTN4R SLIT2 LHX2 TRIM11 ASCL2 ULK1 CDK5

4.18e-051731518GO:0050768
GeneOntologyBiologicalProcesscell projection assembly

ARHGAP24 OFD1 USP9X PPP1R9A TBC1D2B AIF1L TENM2 SLIT2 MARK4 SNX10 PPP1R9B ATXN10 PLD1 PIBF1 HYDIN CFAP46

4.39e-0568515116GO:0030031
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

CACNA1A SEMA3F ARHGAP24 RTN4R PPP1R9A TBC1D2B TENM2 SHANK3 XYLT1 SLIT2 SKOR2 ANAPC2 MARK4 GOLGA8B ULK1 PLD1 MARK2 CDK5

4.85e-0584615118GO:0120035
GeneOntologyBiologicalProcessaxon guidance

SEMA3F RTN4R LAMB3 TENM2 SLIT2 LHX2 NRXN3 SLIT3 ULK1 CDK5

4.90e-0528515110GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

SEMA3F RTN4R LAMB3 TENM2 SLIT2 LHX2 NRXN3 SLIT3 ULK1 CDK5

5.05e-0528615110GO:0097485
GeneOntologyBiologicalProcessmitochondrial NAD transmembrane transport

SLC25A51 SLC25A52

5.32e-0521512GO:1990549
GeneOntologyBiologicalProcessregulation of cell projection organization

CACNA1A SEMA3F ARHGAP24 RTN4R PPP1R9A TBC1D2B TENM2 SHANK3 XYLT1 SLIT2 SKOR2 ANAPC2 MARK4 GOLGA8B ULK1 PLD1 MARK2 CDK5

6.26e-0586315118GO:0031344
GeneOntologyBiologicalProcesspostsynapse assembly

USP9X RTN4R UBE3B SHANK3 NRXN3 PPP1R9B

6.29e-05931516GO:0099068
GeneOntologyBiologicalProcessnegative regulation of nervous system development

SEMA3F RTN4R SLIT2 LHX2 TRIM11 ASCL2 ULK1 CDK5

6.46e-051841518GO:0051961
GeneOntologyBiologicalProcessnegative regulation of organelle organization

PPP1R9A SPTBN1 HIP1R SHANK3 SPDL1 SPTBN4 SPTBN5 CCDC88C SLIT2 GAS2L1 BRCA1 KNL1

6.52e-0542115112GO:0010639
GeneOntologyBiologicalProcessprotein localization to microtubule cytoskeleton

GAS2L1 MARK4 SNX10 PIBF1 GOLGB1

7.16e-05591515GO:0072698
GeneOntologyBiologicalProcessregulation of cellular component size

SEMA3F RTN4R PPP1R9A SPTBN1 HIP1R SHANK3 SPTBN4 SPTBN5 SLIT2 ANAPC2 ULK1 CDK5

7.29e-0542615112GO:0032535
GeneOntologyBiologicalProcesssupramolecular fiber organization

MYH11 CLIP2 USP9X PPP1R9A SPTBN1 HIP1R AIF1L SHANK3 SPTBN4 SPTBN5 CCDC88C SLIT2 GAS2L1 HAUS8 TCHH MYO1F GOLGA8B PPP1R9B PLEC

7.46e-0595715119GO:0097435
GeneOntologyBiologicalProcesscerebellum morphogenesis

CACNA1A USP9X SKOR2 ULK1 CDK5

7.77e-05601515GO:0021587
GeneOntologyBiologicalProcessnegative regulation of axonogenesis

SEMA3F RTN4R SLIT2 ULK1 CDK5

9.10e-05621515GO:0050771
GeneOntologyBiologicalProcesshindbrain morphogenesis

CACNA1A USP9X SKOR2 ULK1 CDK5

1.06e-04641515GO:0021575
GeneOntologyBiologicalProcesscerebellar cortex formation

CACNA1A SKOR2 ULK1 CDK5

1.08e-04341514GO:0021697
GeneOntologyBiologicalProcessregulation of synapse assembly

USP9X RTN4R PPP1R9A UBE3B LRRTM3 SLIT2 LRRTM4 PPP1R9B

1.24e-042021518GO:0051963
GeneOntologyBiologicalProcesscell cycle process

MYBBP1A NPR2 OFD1 PPP2R2D USP9X SPTBN1 HDAC8 SPDL1 CHMP7 HAUS8 BRCA1 CHTF18 ARID2 ANAPC2 MARK4 PKD1 GOLGA8B PPP1R9B ATXN10 PLEC DOT1L PIBF1 TRIM36 KNL1

1.27e-04144115124GO:0022402
GeneOntologyBiologicalProcesschemorepulsion involved in embryonic olfactory bulb interneuron precursor migration

SLIT2 SLIT3

1.59e-0431512GO:0021834
GeneOntologyBiologicalProcessserotonin biosynthetic process from tryptophan

CYP2D7 CYP2D6

1.59e-0431512GO:0006587
GeneOntologyBiologicalProcesscellular response to peptide

NPR2 NFKB1 PPP1R9B

1.64e-04151513GO:1901653
GeneOntologyBiologicalProcesschromosome segregation

OFD1 USP9X SPDL1 CHMP7 HAUS8 BRCA1 CHTF18 ARID2 ANAPC2 GOLGA8B PIBF1 KNL1

1.66e-0446515112GO:0007059
GeneOntologyBiologicalProcessnegative regulation of axon extension

SEMA3F RTN4R SLIT2 CDK5

1.68e-04381514GO:0030517
GeneOntologyBiologicalProcessprotein localization to centrosome

MARK4 SNX10 PIBF1 GOLGB1

1.68e-04381514GO:0071539
GeneOntologyBiologicalProcessnegative regulation of cell growth

SEMA3F RTN4R SLIT2 BRCA1 SLIT3 PPP1R9B ULK1 CDK5

1.72e-042121518GO:0030308
GeneOntologyBiologicalProcesscerebellar cortex development

CACNA1A USP9X SKOR2 ULK1 CDK5

1.74e-04711515GO:0021695
GeneOntologyBiologicalProcessprotein localization to microtubule organizing center

MARK4 SNX10 PIBF1 GOLGB1

1.86e-04391514GO:1905508
GeneOntologyBiologicalProcesscentral nervous system neuron differentiation

CACNA1A SPG11 SHANK3 SPTBN4 SLIT2 SKOR2 ULK1 CDK5

2.02e-042171518GO:0021953
GeneOntologyBiologicalProcessnegative regulation of actin filament polymerization

SPTBN1 HIP1R SPTBN4 SPTBN5 SLIT2

2.25e-04751515GO:0030837
GeneOntologyBiologicalProcessnegative regulation of growth

SEMA3F RTN4R SLIT2 WWC2 BRCA1 SLIT3 PPP1R9B ULK1 CDK5

2.45e-042831519GO:0045926
GeneOntologyBiologicalProcessregulation of extent of cell growth

SEMA3F RTN4R SLIT2 ANAPC2 ULK1 CDK5

2.80e-041221516GO:0061387
GeneOntologyBiologicalProcessnegative regulation of cell development

SEMA3F NPR2 RTN4R SLIT2 ERFE LHX2 TRIM11 ASCL2 ULK1 CDK5

2.82e-0435315110GO:0010721
GeneOntologyBiologicalProcessnegative regulation of protein-containing complex assembly

SPTBN1 HIP1R SPTBN4 SPTBN5 SLIT2 TRIM11 ULK1

2.90e-041731517GO:0031333
GeneOntologyBiologicalProcesscell junction assembly

CACNA1A USP9X RTN4R PPP1R9A UBE3B LRRTM3 SHANK3 SLIT2 NRXN3 LRRTM4 PPP1R9B PLEC CDK5

2.91e-0456915113GO:0034329
GeneOntologyBiologicalProcessregulation of postsynapse assembly

USP9X RTN4R UBE3B PPP1R9B

2.98e-04441514GO:0150052
GeneOntologyBiologicalProcessregulation of microtubule-based process

CHMP7 CCDC88C GAS2L1 HAUS8 BRCA1 MARK4 PKD1 MARK2 TRIM36

3.16e-042931519GO:0032886
GeneOntologyBiologicalProcessregulation of microtubule cytoskeleton organization

CHMP7 CCDC88C GAS2L1 HAUS8 PKD1 MARK2 TRIM36

3.22e-041761517GO:0070507
GeneOntologyBiologicalProcessnegative regulation of developmental growth

SEMA3F RTN4R SLIT2 WWC2 ULK1 CDK5

3.33e-041261516GO:0048640
GeneOntologyBiologicalProcessactin filament organization

PPP1R9A SPTBN1 HIP1R AIF1L SHANK3 SPTBN4 SPTBN5 SLIT2 GAS2L1 MYO1F PPP1R9B PLEC

3.77e-0450915112GO:0007015
GeneOntologyBiologicalProcessactin filament-based process

MYH11 PPP1R9A SPTBN1 HIP1R AIF1L SHANK3 SPTBN4 SPTBN5 CCDC88C SLIT2 GAS2L1 AMOTL1 MYO1F PPP1R9B PLEC EPDR1 CDK5

3.80e-0491215117GO:0030029
GeneOntologyBiologicalProcessnegative regulation of protein depolymerization

SPTBN1 SPTBN4 SPTBN5 CCDC88C GAS2L1

4.98e-04891515GO:1901880
GeneOntologyBiologicalProcessembryonic olfactory bulb interneuron precursor migration

SLIT2 SLIT3

5.25e-0451512GO:0021831
GeneOntologyBiologicalProcessspongiotrophoblast differentiation

ASCL2 HECTD1

5.25e-0451512GO:0060708
GeneOntologyBiologicalProcessNAD transmembrane transport

SLC25A51 SLC25A52

5.25e-0451512GO:0035352
GeneOntologyBiologicalProcessnegative chemotaxis

SEMA3F RTN4R SLIT2 SLIT3

5.28e-04511514GO:0050919
GeneOntologyBiologicalProcessaxon extension involved in axon guidance

SEMA3F SLIT2 SLIT3

5.35e-04221513GO:0048846
GeneOntologyBiologicalProcessneuron projection extension involved in neuron projection guidance

SEMA3F SLIT2 SLIT3

5.35e-04221513GO:1902284
GeneOntologyBiologicalProcessnegative regulation of protein polymerization

SPTBN1 HIP1R SPTBN4 SPTBN5 SLIT2

5.52e-04911515GO:0032272
GeneOntologyBiologicalProcessregulation of neuron projection development

CACNA1A SEMA3F RTN4R PPP1R9A SHANK3 XYLT1 SLIT2 SKOR2 ANAPC2 GOLGA8B ULK1 MARK2 CDK5

5.79e-0461215113GO:0010975
GeneOntologyBiologicalProcesssister chromatid segregation

OFD1 SPDL1 CHMP7 ARID2 ANAPC2 GOLGA8B PIBF1 KNL1

5.79e-042541518GO:0000819
GeneOntologyBiologicalProcesscell division

PPP2R2D USP9X SPTBN1 SPDL1 CHMP7 HAUS8 ANAPC2 MARK4 GOLGA8B ATXN10 PLEC TRIM36 KNL1 CDK5

6.18e-0469715114GO:0051301
GeneOntologyBiologicalProcessprotein depolymerization

SPTBN1 SPTBN4 SPTBN5 CCDC88C GAS2L1 PPP1R9B

6.78e-041441516GO:0051261
GeneOntologyBiologicalProcessregulation of binding

CYP2D6 USP9X HIP1R BLK LHX2 GOLGA8B TRAF3IP3 MARK2 DOT1L CDK5

6.91e-0439615110GO:0051098
GeneOntologyBiologicalProcessmicrotubule bundle formation

OFD1 CCDC88C GAS2L1 TRIM36 HYDIN CFAP46

7.03e-041451516GO:0001578
GeneOntologyBiologicalProcesscell growth

SEMA3F NPR2 USP9X RTN4R SPG11 SLIT2 LHX2 BRCA1 ANAPC2 SLIT3 PPP1R9B ULK1 CDK5

7.03e-0462515113GO:0016049
GeneOntologyBiologicalProcessregulation of nervous system development

SEMA3F RTN4R LRRTM3 SHANK3 SLIT2 LHX2 TRIM11 ASCL2 ANAPC2 LRRTM4 GOLGA8B ULK1 CDK5

7.03e-0462515113GO:0051960
GeneOntologyBiologicalProcessmicrotubule-based process

OFD1 CLIP2 SPG11 SPDL1 CHMP7 CCDC88C GAS2L1 HAUS8 BRCA1 MARK4 PKD1 GOLGA8B MARK2 PIBF1 TRIM36 HYDIN CFAP46 CDK5

7.47e-04105815118GO:0007017
GeneOntologyBiologicalProcessnegative regulation of gene expression, epigenetic

ZNFX1 LHX2 H2AC6 H2AC4 BRCA1 SCMH1 DOT1L

7.54e-042031517GO:0045814
GeneOntologyBiologicalProcessNAD transport

SLC25A51 SLC25A52

7.83e-0461512GO:0043132
GeneOntologyBiologicalProcessacid secretion

CACNA1A TRH HIP1R SNX10

8.07e-04571514GO:0046717
GeneOntologyBiologicalProcessactin cytoskeleton organization

MYH11 PPP1R9A SPTBN1 HIP1R AIF1L SHANK3 SPTBN4 SPTBN5 SLIT2 GAS2L1 AMOTL1 MYO1F PPP1R9B PLEC CDK5

8.30e-0480315115GO:0030036
GeneOntologyBiologicalProcessnegative regulation of protein-containing complex disassembly

SPTBN1 SPTBN4 SPTBN5 CCDC88C GAS2L1

8.47e-041001515GO:0043242
GeneOntologyBiologicalProcessregulation of protein-containing complex assembly

STXBP5 PPP1R9A SPTBN1 HIP1R SPTBN4 SPTBN5 SLIT2 HAUS8 TRIM11 MARK4 ULK1

9.71e-0448915111GO:0043254
GeneOntologyBiologicalProcesswalking behavior

CACNA1A TRH SPG11 SPTBN4

9.79e-04601514GO:0090659
GeneOntologyBiologicalProcessregulation of axon extension

SEMA3F RTN4R SLIT2 ANAPC2 CDK5

1.01e-031041515GO:0030516
GeneOntologyBiologicalProcessregulation of actin filament polymerization

PPP1R9A SPTBN1 HIP1R SPTBN4 SPTBN5 SLIT2

1.03e-031561516GO:0030833
GeneOntologyBiologicalProcessregulation of protein depolymerization

SPTBN1 SPTBN4 SPTBN5 CCDC88C GAS2L1

1.06e-031051515GO:1901879
GeneOntologyCellularComponentactin cytoskeleton

DENND2A AMPH MYH11 ITSN1 PPP1R9A SPTBN1 HIP1R IFIT5 AIF1L CTTNBP2NL SPTBN4 SPTBN5 GAS2L1 MYO1F PPP1R9B MARK2 FERMT3

1.05e-0657615217GO:0015629
GeneOntologyCellularComponentcortical actin cytoskeleton

PPP1R9A SPTBN1 HIP1R SPTBN4 SPTBN5 MYO1F PPP1R9B

5.25e-06931527GO:0030864
GeneOntologyCellularComponentspectrin

SPTBN1 SPTBN4 SPTBN5

3.07e-0591523GO:0008091
GeneOntologyCellularComponentcortical cytoskeleton

PPP1R9A SPTBN1 HIP1R SPTBN4 SPTBN5 MYO1F PPP1R9B

4.46e-051291527GO:0030863
GeneOntologyCellularComponentcell leading edge

AMPH ITSN1 PPP1R9A SPTBN1 HIP1R IFIT5 AIF1L CTTNBP2NL AMOTL1 PPP1R9B PLD1 CDK5

3.03e-0450015212GO:0031252
GeneOntologyCellularComponentglutamatergic synapse

CACNA1A SEMA3F AMPH ITSN1 RTN4R PPP1R9A UBE3B SPTBN1 HIP1R LRRTM3 TENM2 SHANK3 NRXN3 LRRTM4 MARK2 CDK5

3.09e-0481715216GO:0098978
GeneOntologyCellularComponentmitochondrial outer membrane

HK1 MTERF3 NELFB ZNFX1 SAMM50 TRAF3IP3 ULK1 PLEC

3.92e-042411528GO:0005741
GeneOntologyCellularComponentdendrite

CACNA1A CLIP2 ITSN1 RTN4R PPP1R9A HIP1R SPG11 TENM2 SHANK3 SLIT2 MARK4 PPP1R9B ATXN10 PLEC MARK2 CDK5

5.27e-0485815216GO:0030425
GeneOntologyCellularComponentdendritic tree

CACNA1A CLIP2 ITSN1 RTN4R PPP1R9A HIP1R SPG11 TENM2 SHANK3 SLIT2 MARK4 PPP1R9B ATXN10 PLEC MARK2 CDK5

5.41e-0486015216GO:0097447
GeneOntologyCellularComponentsomatodendritic compartment

CACNA1A CLIP2 ITSN1 RTN4R PPP1R9A HIP1R SPG11 TENM2 SHANK3 SPTBN4 SLIT2 MARK4 GOLGA8B PPP1R9B ATXN10 ULK1 PLEC MARK2 CDK5 PDE11A

5.99e-04122815220GO:0036477
GeneOntologyCellularComponentorganelle outer membrane

HK1 MTERF3 NELFB ZNFX1 SAMM50 TRAF3IP3 ULK1 PLEC

1.02e-032791528GO:0031968
GeneOntologyCellularComponentouter membrane

HK1 MTERF3 NELFB ZNFX1 SAMM50 TRAF3IP3 ULK1 PLEC

1.07e-032811528GO:0019867
GeneOntologyCellularComponentlamellipodium

ITSN1 PPP1R9A CTTNBP2NL AMOTL1 PPP1R9B PLD1 CDK5

1.50e-032301527GO:0030027
GeneOntologyCellularComponentribbon synapse

AMPH OTOF LRRTM4

1.60e-03321523GO:0097470
GeneOntologyCellularComponentcell cortex

CLIP2 PPP1R9A SPTBN1 HIP1R SPTBN4 SPTBN5 MYO1F PPP1R9B MARK2

1.61e-033711529GO:0005938
GeneOntologyCellularComponentdendritic spine neck

PPP1R9A PPP1R9B

1.83e-0391522GO:0044326
GeneOntologyCellularComponentAtg1/ULK1 kinase complex

WDR41 ULK1

1.83e-0391522GO:1990316
GeneOntologyCellularComponentfilopodium

MORN4 PPP1R9A TENM2 PPP1R9B CDK5

2.07e-031231525GO:0030175
MousePhenoabnormal miniature excitatory postsynaptic currents

CACNA1A PPP1R9A LRRTM3 SHANK3 NRXN3 OTOF SH3RF2 LRRTM4

1.17e-051161298MP:0004753
DomainSpectrin_repeat

SPTBN1 PPL SPTBN4 SPTBN5 PLEC

2.78e-06291465IPR002017
DomainSPEC

SPTBN1 PPL SPTBN4 SPTBN5 PLEC

4.63e-06321465SM00150
DomainSpectrin/alpha-actinin

SPTBN1 PPL SPTBN4 SPTBN5 PLEC

4.63e-06321465IPR018159
Domain-

SPTBN1 SPTBN4 SPTBN5 GAS2L1 CEP95 PLEC

1.94e-057114661.10.418.10
DomainCH-domain

SPTBN1 SPTBN4 SPTBN5 GAS2L1 CEP95 PLEC

2.66e-05751466IPR001715
DomainACTININ_2

SPTBN1 SPTBN4 SPTBN5 PLEC

2.83e-05231464PS00020
DomainACTININ_1

SPTBN1 SPTBN4 SPTBN5 PLEC

2.83e-05231464PS00019
DomainActinin_actin-bd_CS

SPTBN1 SPTBN4 SPTBN5 PLEC

2.83e-05231464IPR001589
DomainPH_dom-spectrin-type

SPTBN1 SPTBN4 SPTBN5

3.80e-0591463IPR001605
DomainTMEM191C

TMEM191C TMEM191B

6.07e-0521462PF15194
DomainTMEM191B/C

TMEM191C TMEM191B

6.07e-0521462IPR028186
DomainLRRNT

RTN4R LRRTM3 SLIT2 SLIT3 LRRTM4 PKD1

1.20e-04981466IPR000372
DomainLRRNT

RTN4R LRRTM3 SLIT2 SLIT3 LRRTM4 PKD1

1.20e-04981466SM00013
DomainCH

SPTBN1 SPTBN4 SPTBN5 GAS2L1 PLEC

1.54e-04651465SM00033
DomainCH

SPTBN1 SPTBN4 SPTBN5 GAS2L1 PLEC

2.19e-04701465PF00307
DomainCH

SPTBN1 SPTBN4 SPTBN5 GAS2L1 PLEC

2.67e-04731465PS50021
DomainMARK/par1

MARK4 MARK2

3.60e-0441462IPR033624
DomainSpectrin_bsu

SPTBN1 SPTBN4

3.60e-0441462IPR016343
DomainPH

ARHGAP24 ITSN1 SPTBN1 TBC1D2B SPTBN4 SPTBN5 PLD1 FERMT3

4.47e-042291468PF00169
DomainSH3_2

AMPH ITSN1 SHANK3 SH3RF2 SH3D19

5.71e-04861465PF07653
DomainSH3_2

AMPH ITSN1 SHANK3 SH3RF2 SH3D19

5.71e-04861465IPR011511
DomainHexokinase_2

HK1 HKDC1

5.98e-0451462PF03727
DomainKA1

MARK4 MARK2

5.98e-0451462PF02149
DomainHexokinase_BS

HK1 HKDC1

5.98e-0451462IPR019807
DomainKA1_dom

MARK4 MARK2

5.98e-0451462IPR001772
DomainHexokinase_C

HK1 HKDC1

5.98e-0451462IPR022673
DomainHexokinase_N

HK1 HKDC1

5.98e-0451462IPR022672
DomainHexokinase_1

HK1 HKDC1

5.98e-0451462PF00349
DomainKA1

MARK4 MARK2

5.98e-0451462PS50032
Domain-

MARK4 MARK2

5.98e-04514623.30.310.80
DomainHEXOKINASE_2

HK1 HKDC1

5.98e-0451462PS51748
DomainHEXOKINASE_1

HK1 HKDC1

5.98e-0451462PS00378
DomainSpectrin

SPTBN1 SPTBN4 SPTBN5

7.39e-04231463PF00435
DomainPentatricopeptide_repeat

POLRMT IFIT5 XAB2

7.39e-04231463IPR002885
DomainLRRNT

LRRTM3 SLIT2 SLIT3 PKD1

7.79e-04531464PF01462
DomainHexokinase

HK1 HKDC1

8.92e-0461462IPR001312
DomainPlectin

PPL PLEC

1.24e-0371462PF00681
DomainKA1/Ssp2_C

MARK4 MARK2

1.24e-0371462IPR028375
DomainPlectin_repeat

PPL PLEC

1.24e-0371462IPR001101
DomainPLEC

PPL PLEC

1.24e-0371462SM00250
DomainPH

ARHGAP24 ITSN1 SPTBN1 TBC1D2B SPTBN4 SPTBN5 PLD1 FERMT3

1.57e-032781468SM00233
DomainSH3

AMPH ITSN1 SHANK3 BLK SH3RF2 SH3D19 MYO1F

1.57e-032161467SM00326
DomainSH3

AMPH ITSN1 SHANK3 BLK SH3RF2 SH3D19 MYO1F

1.57e-032161467PS50002
DomainPH_DOMAIN

ARHGAP24 ITSN1 SPTBN1 TBC1D2B SPTBN4 SPTBN5 PLD1 FERMT3

1.60e-032791468PS50003
DomainPH_domain

ARHGAP24 ITSN1 SPTBN1 TBC1D2B SPTBN4 SPTBN5 PLD1 FERMT3

1.64e-032801468IPR001849
DomainSH3_domain

AMPH ITSN1 SHANK3 BLK SH3RF2 SH3D19 MYO1F

1.74e-032201467IPR001452
DomainSH3_1

AMPH ITSN1 BLK SH3RF2 SH3D19 MYO1F

1.84e-031641466PF00018
DomainLRR_8

RTN4R LRRTM3 SLIT2 SLIT3 LRRTM4 PKD1

2.28e-031711466PF13855
DomainLRR_TYP

RTN4R LRRTM3 SLIT2 SLIT3 LRRTM4 PKD1

2.70e-031771466SM00369
DomainLeu-rich_rpt_typical-subtyp

RTN4R LRRTM3 SLIT2 SLIT3 LRRTM4 PKD1

2.70e-031771466IPR003591
DomainLAM_G_DOMAIN

SLIT2 NRXN3 SLIT3

3.23e-03381463PS50025
DomainSH3_9

ITSN1 SH3RF2 SH3D19 MYO1F

3.27e-03781464PF14604
DomainLaminin_G_2

SLIT2 NRXN3 SLIT3

3.74e-03401463PF02210
DomainPX

SNX29 SNX10 PLD1

4.90e-03441463SM00312
DomainLamG

SLIT2 NRXN3 SLIT3

4.90e-03441463SM00282
DomainLRR

RTN4R LRRTM3 SLIT2 SLIT3 LRRTM4 PKD1

5.03e-032011466PS51450
DomainARM-type_fold

MYBBP1A USP9X ZNFX1 USP9Y ARID2 ATXN10 HECTD1 TARBP1

5.25e-033391468IPR016024
DomainARM-like

USP9X PPP4R1L USP9Y ARID2 ATXN10 HECTD1 TARBP1

5.39e-032701467IPR011989
DomainCys-rich_flank_reg_C

RTN4R SLIT2 SLIT3 PKD1

5.44e-03901464IPR000483
DomainLRRCT

RTN4R SLIT2 SLIT3 PKD1

5.44e-03901464SM00082
DomainPX

SNX29 SNX10 PLD1

6.63e-03491463PF00787
DomainPX

SNX29 SNX10 PLD1

7.01e-03501463PS50195
Domain-

SNX29 SNX10 PLD1

7.41e-035114633.30.1520.10
DomainConA-like_dom

HNRNPUL1 SLIT2 TRIM11 NRXN3 SLIT3 TRIM36

7.56e-032191466IPR013320
DomainCarboxyPept-like_regulatory

CILP TENM2

7.64e-03171462IPR008969
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNA1A MYBBP1A ARHGAP24 CLIP2 USP9X ITSN1 PPP1R9A SPTBN1 WDR18 ZNFX1 TENM2 SHANK3 SPTBN4 CCDC88C H2AC4 RGS6 SH3D19 GOLGA8B PPP1R9B PKN1 GOLGB1 FERMT3 CDK5

4.57e-119631532328671696
Pubmed

Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.

AMPH CLIP2 ITSN1 PPL SPDL1 CCDC88C AMOTL1 GOLGB1

3.51e-08111153822558309
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CACNA1A DENND2A AMPH MYBBP1A MYH11 HK1 HYOU1 CLIP2 USP9X ITSN1 PPP1R9A SPTBN1 ZNFX1 ALDH1L1 ACTR3B SHANK3 SPTBN4 GAS2L1 PPP1R9B SAMM50 PLEC MARK2 CDK5

8.07e-0814311532337142655
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYBBP1A MYH11 HK1 HYOU1 CHAF1A ITSN1 PPP1R9A SPTBN1 MAFA HKDC1 IFIT5 SPG11 PPL SPTBN4 H2AC6 H2AC4 NRXN3 BRCA1 PPP1R9B ULK1 PLEC GOLGB1 CFAP46

9.25e-0814421532335575683
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

MYBBP1A PPP2R2D ACOT9 WDR18 AIF1L HNRNPUL1 CTTNBP2NL XAB2 PPL HAUS8 PRICKLE3 ARID2 FBXO28 SH3D19 ANAPC2 SAMM50 MARK2 PIBF1 KNL1 CDK5

1.91e-0711551532020360068
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CLIP2 USP9X ITSN1 SPTBN1 IFIT5 ZNFX1 ACTR3B HNRNPUL1 USP9Y DDX27 XAB2 CREBZF SPTBN4 OTOF RALBP1 SH3D19 PKD1 ATXN10 PLEC HECTD1 TARBP1

2.39e-0712851532135914814
Pubmed

A human MAP kinase interactome.

MYH11 CLIP2 CHAF1A ITSN1 SPTBN1 DDX27 RGL1 CEP95 ARID2 SH3D19 PLEC PIBF1 GOLGB1

2.68e-074861531320936779
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

USP9X POLD1 SPEG SPTBN1 TBC1D2B POLRMT SPG11 ALDH1L1 USP9Y TRANK1 ARID2 MARK2 HYDIN

3.45e-074971531336774506
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

MYBBP1A HK1 HYOU1 OFD1 POLD1 ITSN1 SPTBN1 MTERF3 POLRMT SPG11 HNRNPUL1 TIMMDC1 DDX27 SNX29 CHMP7 CCDC138 SAMM50 ATXN10 WDR41 MARK2 PIBF1 GOLGB1

6.45e-0714871532233957083
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

MYBBP1A HK1 HYOU1 ACOT9 MTERF3 POLRMT HNRNPUL1 TIMMDC1 DDX27 SLC25A51 SPTBN5 CHMP7 H2AC6 ARID2 FBXO28 SH3D19 CCDC138 SAMM50 ATXN10 WDR41 MARK2 GOLGB1

7.13e-0714961532232877691
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

OFD1 USP9X PPP1R9A NELFB CTTNBP2NL CCDC88C AMOTL1 CCDC138 PPP1R9B MARK2 PIBF1 HECTD1

7.39e-074461531224255178
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

OFD1 SPTBN1 NELFB HNRNPUL1 CCDC88C HAUS8 WWC2 CEP95 SH3D19 MARK4 CCDC138 PLEC MARK2 PIBF1 HECTD1 GOLGB1

1.41e-068611531636931259
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA3F B4GALNT4 OFD1 SPEG UBE3B SLC35B3 POLRMT HIP1R LAMB3 CCDC88C GAS2L1 MARK4 PKD1 PKN1 ULK1 PLEC DOT1L HECTD1

1.95e-0611051531835748872
Pubmed

Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.

AMPH MYH11 HK1 SPTBN1 SHANK3 PPP1R9B PLEC

1.96e-06131153728634551
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MYBBP1A HYOU1 OFD1 PPP2R2D USP9X PPP1R9A SPTBN1 DDX27 WWC2 TRIM11 NFKB1 CCDC138 PPP1R9B ATXN10 PIBF1 TRIM36 KNL1

4.10e-0610491531727880917
Pubmed

Kinetics of Src homology 3 domain association with the proline-rich domain of dynamins: specificity, occlusion, and the effects of phosphorylation.

AMPH ITSN1 CDK5

4.60e-068153315834155
Pubmed

A protein interaction landscape of breast cancer.

MYBBP1A HK1 HYOU1 USP9X POLRMT HIP1R LAMB3 DDX27 BRCA1 ARID2 PPP1R9B SAMM50 CDK5

5.06e-066341531334591612
Pubmed

A germline-specific class of small RNAs binds mammalian Piwi proteins.

UBE3B TBC1D2B HIP1R TIMMDC1 SLC25A51 CCDC88C GOLGA8B SLC25A52 MARK2 DOT1L CCDC136

5.42e-064501531116751776
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

CCHCR1 HYOU1 OFD1 ACOT9 STXBP5 ITSN1 WDR18 DDX27 CCDC88C HAUS8 CEP95 NFKB1 CCDC138 PLEC PIBF1

5.96e-068531531528718761
Pubmed

WDFY4 is required for cross-presentation in response to viral and tumor antigens.

MYBBP1A MYH11 HYOU1 SPTBN1 MYO1F ULK1 PLEC

6.25e-06156153730409884
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MYBBP1A CHAF1A ITSN1 SPTBN1 NELFB HNRNPUL1 CTTNBP2NL PPL WWC2 PRICKLE3 CHTF18 PKN1 PLEC MARK2

9.02e-067741531415302935
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

MYBBP1A HK1 HYOU1 USP9X SPTBN1 HIP1R WDR18 HNRNPUL1 CTTNBP2NL XAB2 PPL CHMP7 H2AC4 CHTF18 NFKB1 ATXN10 EPDR1 GOLGB1 KNL1

9.73e-0613671531932687490
Pubmed

USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells.

USP9X SPTBN1 ALDH1L1

9.79e-0610153336653359
Pubmed

Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.

OFD1 USP9X ITSN1 HAUS8 CCDC138 PIBF1 CDK5

1.06e-05169153731462741
Pubmed

Functional proteomics mapping of a human signaling pathway.

ITSN1 SPTBN1 HNRNPUL1 XAB2 PPL CREBZF ANAPC2 PKD1 PPP1R9B PLEC GOLGB1 KNL1

1.30e-055911531215231748
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

AMPH MYBBP1A ITSN1 SPTBN1 CTTNBP2NL CHMP7 PKN1 CDK5

1.43e-05246153815345747
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

OFD1 TBC1D2B SNX29 HAUS8 CCDC138 PPP1R9B DOT1L PIBF1

1.65e-05251153829778605
Pubmed

Dual role for LIM-homeodomain gene Lhx2 in the formation of the lateral olfactory tract.

SEMA3F SLIT2 LHX2

1.78e-0512153317329426
Pubmed

NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.

CCDC60 MYBBP1A ADCK5 SPTBN1 HAUS8 H2AC6 NFKB1 PKD1 PLEC

1.81e-05333153932665550
Pubmed

Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity.

PPP1R9A PPP1R9B

1.92e-052153216600521
Pubmed

BRCA1 is a histone-H2A-specific ubiquitin ligase.

H2AC4 BRCA1

1.92e-052153225131202
Pubmed

Molecular evolution of the CYP2D subfamily in primates: purifying selection on substrate recognition sites without the frequent or long-tract gene conversion.

CYP2D7 CYP2D6

1.92e-052153225808902
Pubmed

Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype: a role for the CYP2D6*35 allele in ultrarapid metabolism?

CYP2D7 CYP2D6

1.92e-052153211207030
Pubmed

Anti-ataxic effects of TRH and its analogue, TA-0910, in Rolling mouse Nagoya by metabolic normalization of the ventral tegmental area.

CACNA1A TRH

1.92e-05215328719807
Pubmed

BRCA1 Interacting Protein COBRA1 Facilitates Adaptation to Castrate-Resistant Growth Conditions.

NELFB BRCA1

1.92e-052153230036938
Pubmed

Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.

USP9X USP9Y

1.92e-052153212895410
Pubmed

NF-κB is a critical mediator of BRCA1-induced chemoresistance.

BRCA1 NFKB1

1.92e-052153223435429
Pubmed

USP9X stabilizes BRCA1 and confers resistance to DNA-damaging agents in human cancer cells.

USP9X BRCA1

1.92e-052153231512408
Pubmed

Major Cdk5-dependent phosphorylation sites of amphiphysin 1 are implicated in the regulation of the membrane binding and endocytosis.

AMPH CDK5

1.92e-052153217419807
Pubmed

MARK2/4 promotes Warburg effect and cell growth in non-small cell lung carcinoma through the AMPKα1/mTOR/HIF-1α signaling pathway.

MARK4 MARK2

1.92e-052153235192892
Pubmed

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism.

CYP2D7 CYP2D6

1.92e-05215323123997
Pubmed

Concerted transcriptional regulation by BRCA1 and COBRA1 in breast cancer cells.

NELFB BRCA1

1.92e-052153218071589
Pubmed

SLC25A51 is a mammalian mitochondrial NAD+ transporter.

SLC25A51 SLC25A52

1.92e-052153232906142
Pubmed

The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.

USP9X USP9Y

1.92e-05215328922996
Pubmed

A BRCA1 deficient, NFκB driven immune signal predicts good outcome in triple negative breast cancer.

BRCA1 NFKB1

1.92e-052153226943587
Pubmed

Cytolinker cross-talk: periplakin N-terminus interacts with plectin to regulate keratin organisation and epithelial migration.

PPL PLEC

1.92e-052153217662978
Pubmed

Characterization of Cyp2d22, a novel cytochrome P450 expressed in mouse mammary cells.

CYP2D7 CYP2D6

1.92e-052153211032406
Pubmed

LRRTM3 Regulates Excitatory Synapse Development through Alternative Splicing and Neurexin Binding.

LRRTM3 LRRTM4

1.92e-052153226776509
Pubmed

Usp9y (ubiquitin-specific protease 9 gene on the Y) is associated with a functional promoter and encodes an intact open reading frame homologous to Usp9x that is under selective constraint.

USP9X USP9Y

1.92e-052153212925892
Pubmed

Age-dependent differential regulation of anxiety- and depression-related behaviors by neurabin and spinophilin.

PPP1R9A PPP1R9B

1.92e-052153228700667
Pubmed

Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis.

NELFB BRCA1

1.92e-052153228649985
Pubmed

The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection.

CYP2D7 CYP2D6

1.92e-052153219594327
Pubmed

Coding-noncoding gene expression in intrahepatic cholangiocarcinoma.

CYP2D7 CYP2D6

1.92e-052153226297049
Pubmed

Of mice and (wo)men: genotype-phenotype correlations in BRCA1.

CLIP2 BRCA1

1.92e-052153212915453
Pubmed

A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine.

CYP2D7 CYP2D6

1.92e-052153215051713
Pubmed

Polymorphisms involved in the miR-218-LAMB3 pathway and susceptibility of cervical cancer, a case-control study in Chinese women.

LAMB3 SLIT3

1.92e-052153220163849
Pubmed

Neurabin contributes to hippocampal long-term potentiation and contextual fear memory.

PPP1R9A PPP1R9B

1.92e-052153218183288
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

CCHCR1 MYBBP1A OFD1 PPP2R2D POLD1 UBE3B HNRNPUL1 SLIT2 HAUS8 TRIM11 NFKB1 AMOTL1 SAMM50 ATXN10 PLEC MARK2 PIBF1 CDK5

2.21e-0513211531827173435
Pubmed

Role of neuropilin-2 in the ipsilateral growth of midbrain dopaminergic axons.

SEMA3F SLIT2 SLIT3

2.31e-0513153323534961
Pubmed

alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.

SPTBN1 SPTBN4 SPTBN5

2.31e-0513153318796539
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

MYBBP1A HYOU1 USP9X POLD1 SPTBN1 NELFB WDR18 HNRNPUL1 SAMM50 ATXN10 PLEC HECTD1

2.76e-056381531233239621
Pubmed

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

ZNFX1 WWC2 SCMH1 SLIT3 MYO1F DOT1L PDE11A

2.93e-05198153720881960
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

MYBBP1A PPP1R9A SPTBN1 POLRMT HNRNPUL1 PPP1R9B PLEC MARK2

3.09e-05274153834244482
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYBBP1A HK1 HYOU1 USP9X SPTBN1 POLRMT WDR18 HNRNPUL1 DDX27 XAB2 PLEC HECTD1

3.46e-056531531222586326
Pubmed

Possible roles of Robo1+ ensheathing cells in guiding dorsal-zone olfactory sensory neurons in mouse.

SEMA3F SLIT2 SLIT3

3.65e-0515153323821580
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

CACNA1A AMPH MORN4 ACOT9 USP9X SPTBN1 HIP1R ZNFX1 ACTR3B TENM2 SLC25A51 SHANK3 H2AC4 SLC25A52 PPP1R9B PLEC

4.53e-0511391531636417873
Pubmed

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.

CLIP2 SPTBN1 MARK4 PPP1R9B PLEC MARK2

4.98e-05147153616959763
Pubmed

A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix.

SPTBN1 SPTBN4

5.75e-053153211294830
Pubmed

Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons.

SLIT2 SLIT3

5.75e-053153210102269
Pubmed

Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system.

SLIT2 SLIT3

5.75e-05315329813312
Pubmed

Function of Slit/Robo signaling in breast cancer.

SLIT2 SLIT3

5.75e-053153226542734
Pubmed

The mitochondrial NAD+ transporter SLC25A51 is a fasting-induced gene affecting SIRT3 functions.

SLC25A51 SLC25A52

5.75e-053153235932995
Pubmed

BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations.

NELFB BRCA1

5.75e-053153211739404
Pubmed

Spinophilin/neurabin reciprocally regulate signaling intensity by G protein-coupled receptors.

PPP1R9A PPP1R9B

5.75e-053153217464283
Pubmed

Axonal growth regulation of fetal and embryonic stem cell-derived dopaminergic neurons by Netrin-1 and Slits.

SLIT2 SLIT3

5.75e-053153216840550
Pubmed

SEMA3F prevents metastasis of colorectal cancer by PI3K-AKT-dependent down-regulation of the ASCL2-CXCR4 axis.

SEMA3F ASCL2

5.75e-053153225866254
Pubmed

Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton.

PPP1R9A PPP1R9B

5.75e-05315329653190
Pubmed

The centrosomal OFD1 protein interacts with the translation machinery and regulates the synthesis of specific targets.

OFD1 PKD1

5.75e-053153228450740
Pubmed

Genetic suppression reveals DNA repair-independent antagonism between BRCA1 and COBRA1 in mammary gland development.

NELFB BRCA1

5.75e-053153226941120
Pubmed

Gene-Specific Genetic Complementation between Brca1 and Cobra1 During Mouse Mammary Gland Development.

NELFB BRCA1

5.75e-053153229426838
Pubmed

PKN regulates phospholipase D1 through direct interaction.

PKN1 PLD1

5.75e-053153211259428
Pubmed

β spectrin-dependent and domain specific mechanisms for Na+ channel clustering.

SPTBN1 SPTBN4

5.75e-053153232425157
Pubmed

Intraislet SLIT-ROBO signaling is required for beta-cell survival and potentiates insulin secretion.

SLIT2 SLIT3

5.75e-053153224065825
Pubmed

Slit-mediated repulsion is a key regulator of motor axon pathfinding in the hindbrain.

SLIT2 SLIT3

5.75e-053153216162649
Pubmed

Plakins: a family of versatile cytolinker proteins.

PPL PLEC

5.75e-053153211854008
Pubmed

Identification of bone mineral density associated genes with shared genetic architectures across multiple tissues: Functional insights for EPDR1, PKDCC, and SPTBN1.

SPTBN1 EPDR1

5.75e-053153238683846
Pubmed

The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene.

CYP2D7 CYP2D6

5.75e-05315322574001
Pubmed

Impaired tamoxifen metabolism reduces survival in familial breast cancer patients.

CYP2D6 BRCA1

5.75e-053153218794105
Pubmed

Distinct but overlapping expression patterns of two vertebrate slit homologs implies functional roles in CNS development and organogenesis.

SLIT2 SLIT3

5.75e-053153210349621
Pubmed

Control of AMPK-related kinases by USP9X and atypical Lys(29)/Lys(33)-linked polyubiquitin chains.

USP9X MARK4

5.75e-053153218254724
Pubmed

DOT1L-mediated RAP80 methylation promotes BRCA1 recruitment to elicit DNA repair.

BRCA1 DOT1L

5.75e-053153239172790
Pubmed

Conserved modularity and potential for alternate splicing in mouse and human Slit genes.

SLIT2 SLIT3

5.75e-053153212141424
Pubmed

Proliferating cell nuclear antigen (PCNA) may function as a double homotrimer complex in the mammalian cell.

POLD1 CHAF1A

5.75e-053153215805117
Pubmed

Increasing the complexity of chromatin: functionally distinct roles for replication-dependent histone H2A isoforms in cell proliferation and carcinogenesis.

H2AC6 H2AC4

5.75e-053153223956221
Pubmed

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.

PPP1R9A PPP1R9B

5.75e-053153220305656
Pubmed

Ca2+ influx induced by protease-activated receptor-1 activates a feed-forward mechanism of TRPC1 expression via nuclear factor-kappaB activation in endothelial cells.

TRPC1 NFKB1

5.75e-053153216709572
Pubmed

Identification of the primary gene defect at the cytochrome P450 CYP2D locus.

CYP2D7 CYP2D6

5.75e-05315321978251
Pubmed

MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption.

MARK4 MARK2

5.75e-05315329108484
Pubmed

Paracrine activin B-NF-κB signaling shapes an inflammatory tumor microenvironment in gastric cancer via fibroblast reprogramming.

INHBB NFKB1

5.75e-053153237858201
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

MYBBP1A POLD1 SPTBN1 HIP1R WDR18 ANAPC2 PLEC MARK2 DEPDC7 GOLGB1 KNL1

5.76e-055821531120467437
InteractionCCDC138 interactions

HYOU1 OFD1 ANAPC2 CCDC138 PKN1 SAMM50 TRAF3IP3 PIBF1

3.91e-061231508int:CCDC138
InteractionCEP135 interactions

CCHCR1 OFD1 CHAF1A CCDC88C HAUS8 CEP95 CCDC138 PLD1 PIBF1 TRIM36 GOLGB1

6.29e-0627215011int:CEP135
InteractionCTTNBP2 interactions

PPP2R2D CTTNBP2NL SHANK3 SPDL1 PLEC CCDC136

6.71e-06621506int:CTTNBP2
InteractionCEP120 interactions

OFD1 TBC1D2B HAUS8 CEP95 CCDC138 PIBF1 KNL1

1.45e-051061507int:CEP120
InteractionKRT18 interactions

CCHCR1 OFD1 HAUS8 H2AC4 BRCA1 CCDC138 PKD1 PLEC DOT1L PIBF1 TRIM36 HECTD1 CFAP46

1.57e-0541915013int:KRT18
InteractionAMPH interactions

AMPH ITSN1 SHANK3 PPP1R9B PLD1 CDK5

1.60e-05721506int:AMPH
InteractionRALBP1 interactions

CCHCR1 MYH11 ITSN1 HIP1R PPL CREBZF H2AC6 RALBP1 CCDC136

1.79e-051981509int:RALBP1
InteractionREPS1 interactions

AMPH CHAF1A ITSN1 HIP1R WWC2 TRIM11 RALBP1

1.96e-051111507int:REPS1
InteractionDCTN1 interactions

HYOU1 OFD1 SPTBN1 SHANK3 CCDC88C HAUS8 BRCA1 SH3D19 CCDC138 PPP1R9B MARK2 DOT1L TRIM36 HECTD1

2.15e-0549715014int:DCTN1
InteractionNDC80 interactions

CCHCR1 OFD1 HIP1R HAUS8 CEP95 ANAPC2 CCDC138 PIBF1 TRIM36 CCDC136 KNL1

2.27e-0531215011int:NDC80
InteractionAP2B1 interactions

AMPH ARHGAP24 OFD1 ITSN1 HIP1R SNX29 H2AC4 BRCA1 RALBP1 SH3D19 CCDC138 PPP1R9B

2.36e-0537315012int:AP2B1
InteractionKRT8 interactions

OFD1 USP9X TBC1D2B PPL HAUS8 H2AC4 CCDC138 PKD1 PPP1R9B PLEC PIBF1 TRIM36 HECTD1

2.68e-0544115013int:KRT8
InteractionTMOD1 interactions

OFD1 GAS2L1 HAUS8 AMOTL1 CCDC138 PPP1R9B HECTD1 GOLGB1

2.81e-051611508int:TMOD1
InteractionTPTE2 interactions

OFD1 HAUS8 BRCA1 CCDC138 PIBF1 HECTD1

3.88e-05841506int:TPTE2
InteractionCCDC136 interactions

CCHCR1 HMG20B CEP95 RALBP1 PKN1 TRAF3IP3 PIBF1 CCDC136

3.97e-051691508int:CCDC136
InteractionBFSP1 interactions

CCHCR1 ITSN1 PPL SPDL1 PIBF1

4.19e-05521505int:BFSP1
InteractionATG16L1 interactions

CCHCR1 MYBBP1A OFD1 POLD1 SPEG TBC1D2B NELFB WDR18 HNRNPUL1 SNX29 CEP95 RALBP1 PKD1 PPP1R9B TRAF3IP3 ULK1 PLEC MARK2 TRIM36 GOLGB1 KNL1 FERMT3

4.94e-05116115022int:ATG16L1
InteractionKRT19 interactions

CCHCR1 OFD1 HAUS8 H2AC4 AMOTL1 CCDC138 PKN1 PLEC DOT1L PIBF1

5.14e-0528215010int:KRT19
InteractionRFC1 interactions

POLD1 CHAF1A WDR18 LHX2 H2AC4 BRCA1 CHTF18 DOT1L HECTD1

5.98e-052311509int:RFC1
InteractionDNAJC9 interactions

MYBBP1A MORN4 HYOU1 CHAF1A HNRNPUL1 DDX27 H2AC4 TRIM11 DOT1L HECTD1

7.69e-0529615010int:DNAJC9
InteractionPOC5 interactions

OFD1 HAUS8 TRIM11 ANAPC2 CCDC138 PIBF1

7.75e-05951506int:POC5
InteractionLRRTM4 interactions

LRRTM3 BLK NRXN3 LRRTM4

7.93e-05311504int:LRRTM4
InteractionPCNT interactions

OFD1 POLD1 SPTBN1 HIP1R ANAPC2 CCDC138 SAMM50 PLEC PIBF1

8.28e-052411509int:PCNT
InteractionWDFY4 interactions

MYBBP1A MYH11 HYOU1 SPTBN1 MYO1F ULK1 PLEC

9.04e-051411507int:WDFY4
InteractionNEFM interactions

CCHCR1 ITSN1 SHANK3 SPDL1 PPP1R9B PLEC EPDR1 PIBF1

9.05e-051901508int:NEFM
InteractionPCM1 interactions

CCHCR1 OFD1 ACOT9 USP9X HNRNPUL1 SPDL1 HAUS8 CEP95 RALBP1 CCDC138 PPP1R9B PIBF1

1.01e-0443415012int:PCM1
InteractionRUNDC3A interactions

ITSN1 SPTBN1 SHANK3 RALBP1 EPDR1

1.06e-04631505int:RUNDC3A
InteractionSPAG5 interactions

CCHCR1 OFD1 SHANK3 BRCA1 FBXO28 ANAPC2 PKN1 TRIM36

1.08e-041951508int:SPAG5
InteractionYWHAZ interactions

MYH11 PPP2R2D CLIP2 SPEG CHAF1A SPTBN1 NELFB HIP1R HNRNPUL1 SHANK3 CCDC88C WWC2 BRCA1 PRICKLE3 CEP95 SH3D19 AMOTL1 MARK4 PPP1R9B ULK1 PLEC MARK2 HECTD1

1.16e-04131915023int:YWHAZ
InteractionCEP89 interactions

OFD1 TBC1D2B CCDC88C HAUS8 CCDC138 MARK2 PIBF1

1.17e-041471507int:CEP89
InteractionH1-0 interactions

MYBBP1A H2AC6 H2AC4 TRIM11 RALBP1 FBXO28 MYO1F PPP1R9B CDK5

1.31e-042561509int:H1-0
InteractionUBE2D2 interactions

USP9X HIP1R SHANK3 TRIM11 BRCA1 NFKB1 ANAPC2 PLEC TRIM36 HECTD1

1.39e-0431815010int:UBE2D2
InteractionSYNJ1 interactions

AMPH ITSN1 SHANK3 SH3D19 PPP1R9B CDK5

1.42e-041061506int:SYNJ1
InteractionGLDC interactions

MYBBP1A ARHGAP24 PPP2R2D PPP1R9A SPTBN1 POLRMT HNRNPUL1 PPP1R9B PLEC MARK2

1.50e-0432115010int:GLDC
InteractionH3C14 interactions

CHAF1A H2AC6 H2AC4 BRCA1 RALBP1 PKN1 DOT1L

1.70e-041561507int:H3C14
InteractionRHOB interactions

ACOT9 USP9X ITSN1 PPP1R9A SPTBN1 TBC1D2B HIP1R TENM2 SNX29 CCDC88C RALBP1 SH3D19 PKN1 PLD1 MARK2 DEPDC7 CDK5

1.76e-0484015017int:RHOB
InteractionYWHAB interactions

POLD1 SPEG CHAF1A SPTBN1 NELFB HNRNPUL1 SHANK3 CCDC88C WWC2 H2AC4 PRICKLE3 CEP95 SH3D19 MARK4 PPP1R9B MARK2 DOT1L PIBF1 HECTD1

1.95e-04101415019int:YWHAB
InteractionATAD3B interactions

ARHGAP24 PPP2R2D POLD1 SLC25A51 SPDL1 FBXO28 NFKB1 DOT1L

1.99e-042131508int:ATAD3B
InteractionEXOC4 interactions

CCHCR1 OFD1 HAUS8 H2AC4 NFKB1 ANAPC2 HECTD1 HYDIN

1.99e-042131508int:EXOC4
InteractionFBXO22 interactions

USP9X POLD1 SPEG SPTBN1 TBC1D2B POLRMT SPG11 ALDH1L1 USP9Y TRANK1 ARID2 MARK2 HYDIN

2.05e-0454015013int:FBXO22
InteractionNEFL interactions

ARHGAP24 ITSN1 SLC25A51 SHANK3 PPP1R9B PKN1 SAMM50

2.06e-041611507int:NEFL
InteractionCFAP184 interactions

OFD1 TBC1D2B BLK HAUS8 CEP95 CCDC136 KNL1

2.14e-041621507int:CFAP184
InteractionCDC5L interactions

MYBBP1A POLD1 SPTBN1 HIP1R WDR18 XAB2 BRCA1 ANAPC2 PLEC MARK2 DOT1L DEPDC7 HECTD1 CCDC136 GOLGB1 PURG KNL1

2.17e-0485515017int:CDC5L
InteractionKCTD13 interactions

CACNA1A DENND2A AMPH MYBBP1A MYH11 HK1 HYOU1 CLIP2 USP9X ITSN1 PPP1R9A SPTBN1 ZNFX1 ALDH1L1 ACTR3B SHANK3 SPTBN4 GAS2L1 PPP1R9B SAMM50 PLEC MARK2 CDK5

2.59e-04139415023int:KCTD13
InteractionWHAMMP3 interactions

CCHCR1 TBC1D2B HAUS8 CEP95 PKN1 PIBF1

2.67e-041191506int:WHAMMP3
GeneFamilyEF-hand domain containing|Spectrins

SPTBN1 SPTBN4 SPTBN5

5.32e-0679831113
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R9A BRCA1 SH3RF2 PPP1R9B HYDIN KNL1

4.55e-04181986694
GeneFamilyEF-hand domain containing|Plakins

PPL PLEC

7.97e-048982939
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGAP24 ITSN1 SPTBN1 SPTBN4 PLD1 FERMT3

8.97e-04206986682
CoexpressionFAN_EMBRYONIC_CTX_EX_4_EXCITATORY_NEURON

CACNA1A SPEG SPTBN4 PKD1 GOLGA8B PLEC TARBP1 HYDIN

6.20e-061661538M39026
CoexpressionGSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP

POLD1 DHDDS XYLT1 H2AC4 CHTF18 ANAPC2 DOT1L KNL1

1.22e-051821538M8126
CoexpressionIVANOVA_HEMATOPOIESIS_STEM_CELL

CYP2D7 CYP2D6 PPP1R9A SLIT2 WWC2 NRXN3 LRRTM4 CCDC136

2.08e-051961538MM667
CoexpressionGSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP

CCHCR1 B4GALNT4 ITGAE SPDL1 BRCA1 AMOTL1 MYO1F EPDR1

2.40e-052001538M7962
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AMPH MYH11 B4GALNT4 CILP SPEG AIF1L TENM2 SLIT2 RGS6 SLIT3

9.84e-10186153104780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AMPH MYH11 CILP SPEG AIF1L TENM2 SLIT2 RGS6 SLIT3

1.99e-081891539975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AMPH MYH11 SPEG AIF1L TENM2 SLIT2 RGS6 SLIT3

2.72e-071861538a95744b8649096bd7cfc3591a02841fa411085b3
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AMPH TENM2 SPTBN4 NRXN3 PKD1 GOLGA8B TMEM178B TARBP1

4.05e-071961538676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A AMPH TENM2 SPTBN4 NRXN3 PKD1 GOLGA8B TMEM178B

4.38e-071981538c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A AMPH TENM2 SPTBN4 NRXN3 GOLGA8B TMEM178B TARBP1

4.38e-0719815386d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

CACNA1A AMPH TENM2 SPTBN4 NRXN3 PKD1 TMEM178B TARBP1

4.72e-07200153848d801219bc771d6c7e151dc88ca4c179988de85
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)|Neuronal / cells hierarchy compared to all cells using T-Statistic

CCDC88C SLIT2 RGS6 SH3RF2 SLIT3 LRRTM4 TMEM178B HYDIN

4.72e-0720015380f23e72649a274043bf23e0952a9b5707c516acf
ToppCellmetastatic_Brain-Fibroblasts-Smooth_muscle_cells|Fibroblasts / Location, Cell class and cell subclass

MYH11 SPEG TMEM191C AIF1L ACTR3B TMEM191B TRIM36

1.07e-061541537423f58fc7dcef068458cbf7b4ee989e37227041e
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AMPH ARHGAP24 SPEG LRRTM3 TENM2 RGS6 SLIT3

2.15e-0617115374ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AMPH CHAF1A H2AC6 TCHH ARID2 DEPDC7 KNL1

2.24e-06172153729c8510f26527d487d0fc3543102d067cdb281a6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYH11 CLIP2 SPEG LRRTM3 XYLT1 RGS6 CHTF18

2.51e-061751537b80fe906043b3cb0b3ba761aadc9dc1c364aa1bf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYH11 CLIP2 SPEG LRRTM3 XYLT1 RGS6 CHTF18

2.51e-061751537067c7d89cfdf6ebf70692df64b9b79d752f093dd
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC88C SLIT2 TRIM11 RGS6 SH3RF2 SLIT3 LRRTM4

2.61e-061761537c7be4eaa5eb76ad9389fb9d15ad0934e88d267d1
ToppCellHealthy_Control-Lymphoid-T-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CHAF1A SPTBN1 SPDL1 ERFE LHX2 BRCA1 KNL1

3.14e-061811537ac1ee313910c05b1b3cb497bae14565464919c21
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC88C SLIT2 RGS6 SH3RF2 SLIT3 LRRTM4 HYDIN

3.37e-0618315371645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC88C SLIT2 RGS6 SH3RF2 SLIT3 LRRTM4 HYDIN

3.50e-06184153734e316ad8e7b8667cd8ad61397281802a252744f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC88C SLIT2 RGS6 SH3RF2 SLIT3 LRRTM4 HYDIN

3.50e-06184153730fddbc9696476d4d7f08e53f84ea994a4ed873a
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC88C SLIT2 RGS6 SH3RF2 SLIT3 LRRTM4 HYDIN

3.50e-06184153796926efa220f03d0787322c9519bb9e8f64f74d0
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AMPH MYH11 CILP SPEG TENM2 SLIT2 SLIT3

4.32e-06190153773d94fbae92029745989a8712eed8b99fd84c193
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLD1 CHAF1A H2AC6 H2AC4 BRCA1 CHTF18 KNL1

4.63e-061921537e8d47504b744040a762ec9b670a66cc060b2ae86
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A ARHGAP24 HKDC1 LAMB3 AIF1L PPL TFCP2L1

4.79e-061931537263d185af6ed80e639f864e4966268e0862c61dc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A ARHGAP24 HKDC1 LAMB3 AIF1L PPL TFCP2L1

4.79e-06193153780e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A ARHGAP24 HKDC1 LAMB3 AIF1L PPL TFCP2L1

4.79e-061931537b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DENND2A POLD1 ITSN1 XYLT1 SLIT2 NFKB1 SLIT3

5.85e-0619915378b86c69aaf60feff53aa782559cfece7342a23de
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-LTK---L2|Neuronal / cells hierarchy compared to all cells using T-Statistic

CCDC88C SLIT2 RGS6 SH3RF2 SLIT3 LRRTM4 HYDIN

6.05e-0620015376ebdae4438bc64c6620416f64a7e22fbca2664bf
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-LTK-|Neuronal / cells hierarchy compared to all cells using T-Statistic

CCDC88C SLIT2 RGS6 SH3RF2 SLIT3 LRRTM4 HYDIN

6.05e-062001537081ca331b56f85167acfc73af9d2e91f398f8c4d
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-LTK--|Neuronal / cells hierarchy compared to all cells using T-Statistic

CCDC88C SLIT2 RGS6 SH3RF2 SLIT3 LRRTM4 HYDIN

6.05e-06200153766e2f3e2e9063f17b47621120eb6009405f69e7e
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-LTK|Neuronal / cells hierarchy compared to all cells using T-Statistic

CCDC88C SLIT2 RGS6 SH3RF2 SLIT3 LRRTM4 HYDIN

6.05e-062001537940892bea41fde567f138a896d151acccef03a6a
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Hist1h2al))|Striatum / BrainAtlas - Mouse McCarroll V32

USP9Y ITGAE ERFE H2AC6 H2AC4

9.41e-068215353cee9ee752128dd91e9abc05c9f97b17e64a2a76
ToppCellAdult-Mesenchymal-chondrocyte-D122|Adult / Lineage, Cell type, age group and donor

ALDH1L1 TENM2 SLIT2 SH3D19 SLIT3 CDK5

1.24e-05148153681a1e6fdd942a612bf523c59b8b4974f6ca1fdce
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYH11 SPEG IFIT5 AMOTL1 TARBP1 CCDC136

1.55e-05154153616fdafb5c64d2db321554f87129a962d113f1668
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Lypd1_Gpr88|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

INHBB RTN4R HKDC1 ALDH1L1 SLIT2 LHX2

1.73e-0515715365aee90ad7aaa65fdabc23597451da5e48db8f4e6
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LHX2 RGL1 RGS6 OTOF SLIT3 LRRTM4

2.00e-051611536e3327c296d48e821004e61a573abb75624a6f040
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

B4GALNT4 LRRTM3 OTOP3 XYLT1 NRXN3 LRRTM4

2.07e-051621536d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

B4GALNT4 LRRTM3 OTOP3 XYLT1 NRXN3 LRRTM4

2.07e-0516215365bbd7130d4dad9035e73a439dda568195c136f31
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

B4GALNT4 LRRTM3 OTOP3 XYLT1 NRXN3 LRRTM4

2.07e-051621536eed223e61c8162a2fe004ab4e09de5e037be7553
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

B4GALNT4 LRRTM3 OTOP3 XYLT1 NRXN3 LRRTM4

2.07e-051621536e35ddce830e20ebeac1a2c405293fc4a5323dd4a
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B4GALNT4 STXBP5 HIP1R H2AC4 TMEM191B DEPDC7

2.07e-05162153680619a93c57fe16daf91dc571874ef9ac888953d
ToppCelldroplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMB3 ALDH1L1 SNX29 XYLT1 SPTBN4 DEPDC7

2.30e-051651536354978d4f35154d7b2e36e94de669e045adef512
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHAF1A SPDL1 ERFE BRCA1 CHTF18 KNL1

2.38e-05166153621ba5fd755c0fb31ada42a1b5d60bede0153323d
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D122|Adult / Lineage, Cell type, age group and donor

SEMA3F SPEG AIF1L SHANK3 GAS2L1 FIGLA

2.54e-0516815368c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1A B4GALNT4 HIP1R SPTBN4 LRRTM4 TMEM178B

2.63e-05169153696a2aec9acf8a6f966973c035e5ade456cf47772
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH11 SPEG NRXN3 RGS6 SLIT3 PLD1

2.72e-05170153699dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AMPH ARHGAP24 SLIT2 RGS6 AMOTL1 SLIT3

2.72e-0517015365570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH11 SPEG NRXN3 RGS6 SLIT3 PLD1

2.72e-0517015363a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH11 SPEG NRXN3 RGS6 SLIT3 PLD1

2.72e-051701536cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DENND2A MYH11 LRRTM3 ERFE RGS6 SLIT3

3.09e-051741536015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCell10x3'2.3-week_17-19-Neuro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

B4GALNT4 AIF1L NRXN3 SH3D19 LRRTM4 TMEM178B

3.20e-051751536bbce8b1a160b414c0bf643c21c4e5e78fbccb7e1
ToppCelldroplet-Lung-21m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CHAF1A SPDL1 ERFE BRCA1 CHTF18 KNL1

3.20e-0517515366751ee4b312d7f87275f2c35e5878cfc3be3ebe3
ToppCell10x3'2.3-week_17-19-Neuro-stroma-schwann_cells|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

B4GALNT4 AIF1L NRXN3 SH3D19 LRRTM4 TMEM178B

3.20e-0517515368b010220cdfb680ec839572f4933adfb85045ea6
ToppCell10x3'2.3-week_17-19-Neuro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

B4GALNT4 AIF1L NRXN3 SH3D19 LRRTM4 TMEM178B

3.20e-0517515360b579aeadcc06be83627391c0b01bd8605fdbdf3
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC88C SLIT2 RGS6 SH3RF2 SLIT3 LRRTM4

3.30e-05176153607abf29d681abdd6c7cc87f9eaf9377e92ce212c
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH11 LRRTM3 SPDL1 SLIT3 VPS37D KNL1

3.30e-05176153645c6983ab671b0f306e7390320bd84f848e474cc
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC88C SLIT2 RGS6 SH3RF2 SLIT3 LRRTM4

3.41e-0517715368b003ed7887479c3a010ef37dd981b748256bda7
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC88C SLIT2 RGS6 SH3RF2 SLIT3 LRRTM4

3.51e-0517815365d6297f34e104bacefb25c4e2338b50fe13dd19a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

POLD1 CHAF1A BRCA1 CHTF18 DOT1L KNL1

3.63e-05179153688d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TENM2 SLIT2 RGS6 SH3RF2 LRRTM4 TMEM178B

3.86e-05181153657994ff4ecffb15653aee00644d9f887f5e3461d
ToppCell10x5'-bone_marrow-Lymphocytic_B-Pre-B|bone_marrow / Manually curated celltypes from each tissue

DENND2A SPTBN1 MAFA BLK H2AC6 SCMH1

3.98e-051821536a5fd392178c2f533e265d2e3ce63b90c2553e4c1
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHAF1A ERFE BRCA1 CHTF18 DEPDC7 KNL1

3.98e-05182153611494a66d986297b837332ee9d382b71b9f22591
ToppCellB_cells-ABCs|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CLIP2 PPP4R1L ASCL2 MYO1F KNL1 FERMT3

4.10e-051831536bf9c6fe3ce4e44e4056027257eab8448c39c4fb8
ToppCellsevere-multiplets|severe / disease stage, cell group and cell class

HKDC1 SPTBN5 HAUS8 H2AC6 DEPDC7 KNL1

4.10e-05183153678af8df48f0fe49ac37ccec0ad7b2993883b1148
ToppCellCV-Healthy-7|CV / Virus stimulation, Condition and Cluster

C14orf93 HIP1R PPP4R1L CCDC88C MARK4 ULK1

4.23e-0518415360e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SEMA3F HIP1R AIF1L CTTNBP2NL SHANK3 SH3RF2

4.36e-051851536a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ACOT9 LAMB3 CTTNBP2NL HMG20B NFKB1 DOT1L

4.49e-0518615360dce13e15c3bf32610bf2dad31253b52a39cff87
ToppCellfacs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPDL1 ERFE H2AC4 BRCA1 CHTF18 KNL1

4.49e-0518615369feef5936985e936b3d88f9d1bb012abb6468570
ToppCellfacs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPDL1 ERFE H2AC4 BRCA1 CHTF18 KNL1

4.49e-05186153689f5b06bc56674af304912d481ac697c7c870904
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A LAMB3 PPL TFCP2L1 RGS6 SH3D19

4.63e-05187153687b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A LAMB3 PPL TFCP2L1 RGS6 SH3D19

4.63e-05187153642a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A LAMB3 PPL TFCP2L1 RGS6 SH3D19

4.63e-05187153664afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A PPL TFCP2L1 SH3D19 SNX10 HECTD1

4.63e-05187153677886f99c229610abd28c4c370d2c7d1536c9782
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP2 SH3RF2 SH3D19 SNX10 DOT1L HECTD1

4.63e-051871536f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

PPP1R9A LRRTM3 TENM2 RGS6 SH3RF2 TMEM178B

4.91e-0518915369c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A LAMB3 PPL TFCP2L1 TMEM178B HYDIN

4.91e-051891536aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A ARHGAP24 CLIP2 TFCP2L1 SNX10 TMEM178B

4.91e-0518915368c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A LAMB3 PPL TFCP2L1 TMEM178B HYDIN

4.91e-0518915368977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A ARHGAP24 CLIP2 TFCP2L1 SNX10 TMEM178B

4.91e-0518915365d902a4660a27548764bf04c6de152b565da835c
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3F TRPC1 SPTBN1 LRRTM3 SHANK3 AMOTL1

5.05e-051901536a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3F TRPC1 SPTBN1 LRRTM3 SHANK3 AMOTL1

5.05e-05190153625525fee1da8a808034d9c916159fd0b6b26bce8
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery|Children_(3_yrs) / Lineage, Cell type, age group and donor

SEMA3F HIP1R AIF1L CTTNBP2NL SHANK3 SH3RF2

5.05e-051901536f6c38d197fd9d69a4f97cb2e72cd4747984c1a86
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DENND2A AMPH MYH11 LRRTM3 RGS6 SLIT3

5.05e-051901536d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

DENND2A MYH11 SPEG LRRTM3 RGS6 SLIT3

5.20e-051911536fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A B4GALNT4 SPTBN4 TRANK1 NRXN3 OTOF

5.51e-051931536be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellControl-Fibroblasts-Vascular_smooth_muscle|Control / group, cell type (main and fine annotations)

DENND2A AIF1L SHANK3 SLIT2 SLIT3 LRRTM4

5.51e-05193153660e44aac8be0430ad35e20eb98b1b700d76a0427
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A B4GALNT4 SPTBN4 TRANK1 NRXN3 OTOF

5.51e-0519315360c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A B4GALNT4 SPTBN4 TRANK1 NRXN3 OTOF

5.51e-0519315368689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPP1R9A SNX29 TFCP2L1 SCMH1 SH3D19 TMEM178B

5.67e-0519415367002937e8903e037332a215d00fbc7c7843b33f2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP24 PPP1R9A HKDC1 AIF1L SNX29 TFCP2L1

5.67e-0519415365eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SEMA3F SPTBN1 CTTNBP2NL SHANK3 NRXN3 SH3D19

5.67e-05194153668004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|lung / Disease (COVID-19 only), tissue and cell type

DENND2A MYH11 SPEG RGS6 SLIT3 LRRTM4

5.67e-0519415365e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCellfacs-Thymus-nan-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLD1 CHAF1A H2AC4 BRCA1 CHTF18 KNL1

5.84e-05195153693c345e70d6c8ff5d12fd63d73228c1700b804a0
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SPTBN1 LRRTM3 TENM2 SLIT2 SLIT3 TMEM178B

5.84e-0519515360e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A TENM2 SLIT2 LHX2 RGS6 CCDC136

5.84e-051951536787e95fb59c40bba784544b662fac37606ae1427
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPP1R9A SLC35B3 AIF1L PPL TFCP2L1 RALBP1

6.01e-051961536c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

OFD1 SPTBN1 HIP1R BLK CHMP7 GOLGA8B

6.01e-051961536c225c8eb2fe9a10f0cf574c7d8b6206887aac2df
ToppCellCOVID_non-vent-Lymphocytic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

OFD1 SPTBN1 USP9Y TRANK1 GOLGA8B TRAF3IP3

6.18e-051971536c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A AMPH SLIT2 SLIT3 LRRTM4 PURG

6.18e-05197153644673c38384453207871d3fd8e8ba9093cc06bc5
ToppCellBronchus_Control_(B.)|World / Sample group, Lineage and Cell type

MAFA LAMB3 BLK SH3RF2 NFKB1 GOLGB1

6.18e-051971536b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1A AMPH TRH LRRTM3 TENM2 TMEM178B

6.35e-0519815368f25e8dff42bad8e779ca618bdb1cb1610667962
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A AMPH SPTBN4 NRXN3 GOLGA8B TARBP1

6.35e-0519815364ca5ff320905ab4ff60ed90a5522227c782142a6
Drugplakin

SPTBN1 DHDDS PPL SPTBN4 SPTBN5 GAS2L1 PLEC

1.34e-06821537CID000018752
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTBN1 SPTBN4

1.51e-0441492DOID:0050882 (implicated_via_orthology)
Diseasesolanidine measurement

CYP2D7 CYP2D6

1.51e-0441492EFO_0800966
Diseasevisual impairment and progressive phthisis bulbi (implicated_via_orthology)

MARK4 MARK2

1.51e-0441492DOID:0070356 (implicated_via_orthology)
DiseaseAtaxia

CACNA1A HK1 PIBF1

2.67e-04251493C0004134
Diseaseelectrocardiography

MYH11 ARHGAP24 CILP SPEG SPTBN1 ZNFX1 TRANK1 RGS6 PLEC CCDC136

3.78e-0453014910EFO_0004327
Diseasesexual dimorphism measurement

SEMA3F DDX27 SPTBN5 H2AC6 H2AC4 TRANK1 NRXN3 SCMH1 SLIT3 PKD1 MYO1F SNX10 PLEC DOT1L VPS37D

4.98e-04110614915EFO_0021796
DiseaseCerebral ventriculomegaly

CCDC88C HYDIN

5.23e-0471492C1531647
DiseaseHydrocephalus Ex-Vacuo

CCDC88C HYDIN

5.23e-0471492C0270720
DiseaseCommunicating Hydrocephalus

CCDC88C HYDIN

5.23e-0471492C0009451
DiseaseFetal Cerebral Ventriculomegaly

CCDC88C HYDIN

5.23e-0471492C2936718
DiseasePost-Traumatic Hydrocephalus

CCDC88C HYDIN

5.23e-0471492C0477432
DiseaseObstructive Hydrocephalus

CCDC88C HYDIN

5.23e-0471492C0549423
Diseasebitter non-alcoholic beverage consumption measurement

AMPH ITSN1 VPS37D

5.62e-04321493EFO_0010093
DiseaseCongenital Hydrocephalus

CCDC88C HYDIN

6.95e-0481492C0020256
DiseaseAqueductal Stenosis

CCDC88C HYDIN

6.95e-0481492C2936786
DiseaseTremor, Neonatal

CYP2D6 TRH

8.91e-0491492C0235843
DiseaseTremor, Perioral

CYP2D6 TRH

8.91e-0491492C0235078
DiseaseNerve Tremors

CYP2D6 TRH

8.91e-0491492C0235083
DiseaseTremor, Limb

CYP2D6 TRH

8.91e-0491492C0235081
DiseaseTremor, Muscle

CYP2D6 TRH

8.91e-0491492C0235082
DiseaseSenile Tremor

CYP2D6 TRH

8.91e-0491492C0149840
Diseaseunderweight body mass index status

NRXN3 RGS6

8.91e-0491492EFO_0005936
DiseasePill Rolling Tremor

CYP2D6 TRH

8.91e-0491492C0751564
DiseaseTremor, Semirhythmic

CYP2D6 TRH

8.91e-0491492C0751565
DiseaseHydrocephalus

CCDC88C HYDIN

8.91e-0491492C0020255
DiseaseAction Tremor

CYP2D6 TRH

8.91e-0491492C0234376
DiseasePassive Tremor

CYP2D6 TRH

8.91e-0491492C0234377
DiseaseStatic Tremor

CYP2D6 TRH

8.91e-0491492C0234378
DiseaseResting Tremor

CYP2D6 TRH

8.91e-0491492C0234379
DiseaseIntermittent Tremor

CYP2D6 TRH

8.91e-0491492C0234372
DiseaseFine Tremor

CYP2D6 TRH

8.91e-0491492C0234373
DiseaseCoarse Tremor

CYP2D6 TRH

8.91e-0491492C0234374
DiseaseMassive Tremor

CYP2D6 TRH

8.91e-0491492C0234375
DiseasePersistent Tremor

CYP2D6 TRH

8.91e-0491492C0234370
DiseaseContinuous Tremor

CYP2D6 TRH

8.91e-0491492C0234371
DiseaseDarkness Tremor

CYP2D6 TRH

8.91e-0491492C0234381
DiseaseInvoluntary Quiver

CYP2D6 TRH

8.91e-0491492C1527384
DiseaseSaturnine Tremor

CYP2D6 TRH

8.91e-0491492C0040827
Diseasebrain connectivity measurement

SEMA3F CYP2D7 CYP2D6 CHMP7 CCDC88C SLIT2 PLEC TRIM36

1.01e-034001498EFO_0005210
Diseasematurity-onset diabetes of the young (implicated_via_orthology)

MAFA HKDC1

1.11e-03101492DOID:0050524 (implicated_via_orthology)
Diseaseretinitis pigmentosa (is_implicated_in)

HK1 OFD1 HKDC1

1.17e-03411493DOID:10584 (is_implicated_in)
Diseasemonocyte percentage of leukocytes

CCHCR1 UBE3B SNX29 CHMP7 LHX2 H2AC6 BRCA1 NFKB1 MARK4 MYO1F VPS37D

1.26e-0373114911EFO_0007989
Diseasediet measurement, adiponectin measurement

SLIT2 PDE11A

1.35e-03111492EFO_0004502, EFO_0008111
DiseaseTremor

CYP2D6 TRH

1.35e-03111492C0040822
Diseasemean arterial pressure, alcohol drinking

BLK H2AC6 SLIT3 TRIM36

1.56e-03981494EFO_0004329, EFO_0006340
Diseasewaist circumference

PPP1R9A ALDH1L1 LHX2 NRXN3 SLIT3 ATXN10 PIBF1 PURG

1.57e-034291498EFO_0004342
DiseaseMouth Diseases

CHAF1A BRCA1

1.62e-03121492C0026636
DiseaseADHD symptom measurement

ACTR3B LRRTM4

1.62e-03121492EFO_0007860
Diseaserisky sexual behaviour measurement

DHDDS TENM2 BLK XYLT1 LRRTM4

1.71e-031691495EFO_0007877
Diseasemean platelet volume

SEMA3F MYH11 STXBP5 SPTBN1 HIP1R SHANK3 TRANK1 PRICKLE3 FBXO28 MARK4 PLEC VPS37D FERMT3

2.06e-03102014913EFO_0004584
Diseasedisease recurrence, colon carcinoma

AMOTL1 ANAPC2 LRRTM4

2.20e-03511493EFO_0004952, EFO_1001950
Diseasetotal brain volume change measurement

LRRTM4 WDR41

2.21e-03141492EFO_0021504
Diseasephoneme awareness

ZNFX1 DDX27

2.21e-03141492EFO_0021812
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

MYH11 DBP PKD1

2.46e-03531493C4707243
Diseasemean reticulocyte volume

HK1 CHAF1A ITSN1 CHTF18 NFKB1 MARK4 SNX10 TRAF3IP3 VPS37D GOLGB1 CDK5

2.52e-0379914911EFO_0010701
DiseaseDrug habituation

CYP2D6 TENM2 XYLT1 NRXN3

2.80e-031151494C0013170
DiseaseDrug abuse

CYP2D6 TENM2 XYLT1 NRXN3

2.80e-031151494C0013146
DiseasePrescription Drug Abuse

CYP2D6 TENM2 XYLT1 NRXN3

2.80e-031151494C4316881
DiseaseSubstance-Related Disorders

CYP2D6 TENM2 XYLT1 NRXN3

2.80e-031151494C0236969
DiseaseDrug Use Disorders

CYP2D6 TENM2 XYLT1 NRXN3

2.80e-031151494C0013222
DiseaseDrug Dependence

CYP2D6 TENM2 XYLT1 NRXN3

2.80e-031151494C1510472
DiseaseSubstance Dependence

CYP2D6 TENM2 XYLT1 NRXN3

2.80e-031151494C0038580
DiseaseSubstance Use Disorders

CYP2D6 TENM2 XYLT1 NRXN3

2.80e-031151494C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

CYP2D6 TENM2 XYLT1 NRXN3

2.80e-031151494C0029231
DiseaseSubstance abuse problem

CYP2D6 TENM2 XYLT1 NRXN3

2.89e-031161494C0740858
Diseaselymphocyte measurement

HK1 ARID2 NFKB1 ULK1

2.98e-031171494EFO_0803546
Diseaseinformation processing speed, response to cranial radiation therapy

XYLT1 SLIT3 TMEM178B

3.18e-03581493EFO_0004363, EFO_0010950
Diseaseage at first birth measurement

CACNA1A SEMA3F DENND2A RGS6

3.26e-031201494EFO_0009101
DiseaseSchizophrenia

RTN4R SHANK3

3.67e-03181492cv:C0036341
DiseasePR interval

MYH11 ARHGAP24 UBE3B SPTBN1 ALDH1L1 CEP95 ARID2 PLEC

3.77e-034951498EFO_0004462
Diseasevital capacity

DENND2A MTERF3 HKDC1 DHDDS WDR18 TENM2 SCMH1 LRRTM4 MYO1F WDR41 DOT1L TMEM178B PIBF1 PDE11A

4.05e-03123614914EFO_0004312
DiseaseDeaf Mutism

POLD1 OTOF

4.53e-03201492C4082305
DiseaseDeafness, Acquired

POLD1 OTOF

4.53e-03201492C0751068
DiseaseHearing Loss, Extreme

POLD1 OTOF

4.53e-03201492C0086395
DiseaseComplete Hearing Loss

POLD1 OTOF

4.53e-03201492C0581883
DiseaseBilateral Deafness

POLD1 OTOF

4.53e-03201492C3665473
DiseasePrelingual Deafness

POLD1 OTOF

4.53e-03201492C0011052
Diseasepolymyositis

UBE3B BLK

4.53e-03201492EFO_0003063

Protein segments in the cluster

PeptideGeneStartEntry
GLLKARQERRLAEIN

AIF1L

16

Q9BQI0
DQRLGQQRAEDFLRK

CACNA1A

846

O00555
EFDIEREQLRAKLNR

CTTNBP2NL

241

Q9P2B4
EKVVQGLFDNFLRLR

CHTF18

646

Q8WVB6
GLNQRVRVLDERKAL

EPDR1

71

Q9UM22
EREIRNVELLKLRFG

ANAPC2

536

Q9UJX6
RLRENEFDPKGRRQL

C2orf80

21

Q0P641
NDVDDQLKRIFRLLG

CDK5

206

Q00535
LRALTALFKEQRNRE

ATXN10

26

Q9UBB4
FGRRLQRDLKRVVDA

ACTR3B

331

Q9P1U1
LAIRNDEELNKLLGR

H2AW

86

Q7L7L0
DERRKGLAFLDELRQ

ARID2

11

Q68CP9
LRRLGNENDKERIQI

CFAP46

566

Q8IYW2
EEELFRQGELNKGRR

ACOT9

226

Q9Y305
NLKDEDGRLRDPFRI

PPP2R2D

141

Q66LE6
RNKLEGEIRRLHDFN

AMOTL1

501

Q8IY63
KAQAERLLRELADNR

CLIP2

481

Q9UDT6
TLRVLEDRALKRGFQ

ADCK5

166

Q3MIX3
NRLLIRAREDFGVEL

NPR2

311

P20594
LLKLLDFQNREEFRR

DEPDC7

346

Q96QD5
EEIRRLFQQKLDELG

DOT1L

541

Q8TEK3
ARQQQFLEELRRKGF

ANO9

51

A1A5B4
EKNKLRLQRDQERLG

CHAF1A

331

Q13111
QERLGKQLKLRAERE

CHAF1A

341

Q13111
QRLEALRRFKDEQID

DDX27

501

Q96GQ7
FKRQEAEGTRLQREL

AMPH

46

P49418
NERERNRVKLVNLGF

ASCL2

56

Q99929
RQEERGIQKFRAFVL

CCDC60

411

Q8IWA6
AGIKEEIRRQEFLLN

RALBP1

396

Q15311
GLINFEKRRREFEVI

RGL1

441

Q9NZL6
LKDQVGRDQFLRFLE

RGS6

341

P49758
LRGREAELKQRVEAF

OFD1

296

O75665
LLRRDRQAQKAGQLF

OTOP3

76

Q7RTS5
NRQLRGFSKEEVIRL

MAFA

241

Q8NHW3
DEDAFQGIRRLKELI

LRRTM4

101

Q86VH4
QALFERGERRLNLDV

INHBB

236

P09529
ELQRLQEENGRLARK

CCDC88C

636

Q9P219
NFTLDVDVGKQRRRL

ITGAE

726

P38570
IFDRNRKDELPRLQL

PDE11A

856

Q9HCR9
LQLREELEALRRQKG

PPL

1011

O60437
RRQKGAREAEVLLLQ

PPL

1021

O60437
FQLLLKGAVRQRERA

ERFE

136

Q4G0M1
IRDLFIDGRSKNIRQ

NRXN3

611

Q9Y4C0
RERFVDSKRARELQG

NELFB

271

Q8WX92
REKLQDGRITIREFF

KNL1

1886

Q8NG31
FRRNLLRQENTGVDK

LHX2

321

P50458
VVDKIRENRGLDRLN

HK1

841

P19367
NLAEFERRAEKNLLI

HAUS8

166

Q9BT25
LERLLGKFGQDAQRI

NUDT13

76

Q86X67
LFAEQKLRIQARRDE

MYBBP1A

796

Q9BQG0
ELRAFSQQRKRENLG

PRICKLE3

156

O43900
DFIRQRGLKEEGLFR

ARHGAP24

161

Q8N264
RARESQDRKIFRGLE

BRCA1

1751

P38398
GLRQRLLDEQFAVLR

HIP1R

611

O75146
RSEFLEKLQRARGQV

HECTD1

721

Q9ULT8
ELRLRERLAGLFNEQ

HYOU1

276

Q9Y4L1
LTFDRGIQQALRERK

HYDIN

2316

Q4G0P3
NAEDIFRKALRLENI

IFIT5

356

Q13325
FAEELQKRERFLLER

CCDC138

201

Q96M89
RGFIQERELRRQDAK

DENND2A

956

Q9ULE3
ERELRRQDAKGLFEV

DENND2A

961

Q9ULE3
RLRLRDLQEAFQRKG

CHMP7

71

Q8WUX9
RFLRLLDLAQEGLKE

CYP2D6

201

P10635
QLFRRLEEEFLANAR

GAS2L1

516

Q99501
FRSQGRKEAERQLLA

BLK

126

P51451
GLARANNELLKRLQE

C14orf93

81

Q9H972
ENFERGNLELEKRRQ

ITSN1

356

Q15811
GEQNARLAELERKLR

FBXO28

311

Q9NVF7
FEEGLNIQKQRLRDL

CEP95

696

Q96GE4
GQRLARRLQELERDK

CCHCR1

666

Q8TD31
DGQNLKELRERVLRG

MARK2

251

Q7KZI7
FDGHNLKELRERVLR

MARK4

256

Q96L34
DLREQALRFGRLRNA

LAMB3

591

Q13751
RAAFLEKENALLRQE

DBP

286

Q10586
NAKERERIKNLNRGF

FIGLA

71

Q6QHK4
NDAVLGILRLRRKFE

HDAC8

156

Q9BY41
LLNRGQKERLREQEE

GOLGA8B

326

A8MQT2
LAIRNDEELNKLLGR

H2AC4

86

P04908
LAIRNDEELNKLLGR

H2AC6

86

Q93077
KEERQRLREAGLVAQ

C7orf50

76

Q9BRJ6
KLSARREERVQGFLQ

DHDDS

301

Q86SQ9
REERVQGFLQALELK

DHDDS

306

Q86SQ9
AREKLLRLGIFRQVD

SAMM50

86

Q9Y512
GRLQIEKRLRELSDF

POLRMT

1006

O00411
RKDLEDQEQLLRRFG

POLD1

1086

P28340
NRQIIARGLLDIFRD

PPP4R1L

61

Q9P1A2
GLRDLKRVNLAQVDR

OTOF

1141

Q9HC10
RRLLVAELQRGFFDK

PKD1

3246

P98161
DLKENQRGRFLRIRQ

PURG

186

Q9UJV8
LKVNELREELQRRGL

HNRNPUL1

6

Q9BUJ2
ERLDNRLGFFQKELE

MTERF3

256

Q96E29
EFLDQNKAREAELRR

HMG20B

191

Q9P0W2
QRLAGRDLKRLAAND

RTN4R

291

Q9BZR6
ERLNFLRFLLKDGQL

USP9X

656

Q93008
RKLERARDLFEQALD

XAB2

571

Q9HCS7
NLKRDRVESRAGFNL

TRIM36

531

Q9NQ86
EGKLLRARNRRQLFA

TMEM178B

76

H3BS89
NNDKRQFLLERLLDA

SNX29

6

Q8TEQ0
RAEDRFLRTEQGLLL

SEMA3F

651

Q13275
SFKRGDRIQILERLD

SH3D19

681

Q5HYK7
DNRDGRQRKQELEKL

TMEM191B

61

P0C7N4
DNRDGRQRKQELEKL

TMEM191C

61

A6NGB0
LREAIKRRNEFDLDI

HKDC1

636

Q2TB90
DENAFNGIRRLKELI

LRRTM3

101

Q86VH5
IREEQFLGRRKQLED

PLD1

171

Q13393
RDAILQLRRDGFRNL

SLC25A51

66

Q9H1U9
QRALDIERKLFANER

SPDL1

401

Q96EA4
FGLIELQLIQDKRRR

SLC35B3

126

Q9H1N7
EKARVLDQARQRALG

TENM2

2691

Q9NT68
EDEVRNLRKINRDLF

WDR18

406

Q9BV38
NQKLGLLREALERRL

PKN1

261

Q16512
RDAVLQLRRDGFRNL

SLC25A52

66

Q3SY17
EIRLLENRKLGDFQD

TFCP2L1

76

Q9NZI6
LARARLALDERGQKL

STXBP5

1101

Q5T5C0
LRGQELEDRRNFLEF

SPTBN5

2246

Q9NRC6
LEDRRNFLEFLQRVD

SPTBN5

2251

Q9NRC6
ARLRLRLDGSDNKND

SCMH1

86

Q96GD3
RGKLDERHRLFQLNR

SPTBN1

1691

Q01082
LQAGLEVERLRLRNF

B4GALNT4

1001

Q76KP1
DFIQLLVRKLRGDDE

ALDH1L1

386

O75891
QGRLLEERKRLQADL

CCDC136

706

Q96JN2
RNKREDRTFLVGNLE

CILP

721

O75339
VGNLEIRERRLFNLD

CILP

731

O75339
RFLRLLDLAQEGLKE

CYP2D7

201

A0A087X1C5
LSGRNALQDEKRRLE

MYH11

1721

P35749
ERGAFQDLKQLERLR

SLIT3

101

O75094
RNEILDKLARNGVFL

SPG11

936

Q96JI7
QDLSKFRNEIRDLLG

TRPC1

766

P48995
FRRRNLELEEKGKAQ

TRAF3IP3

66

Q9Y228
ARFIRKQGLDRLFLE

XYLT1

456

Q86Y38
QNVLGEFERLRRLLA

TRIM11

176

Q96F44
GVLEDERFQRLLKQA

WWC2

1111

Q6AWC2
LDKLQFFEERRRSLE

SPEG

401

Q15772
REARGFLIKVLVQDR

SPEG

1826

Q15772
RGRAGKFLDEERLLQ

SHANK3

61

Q9BYB0
DRLRELFGKDEQQRI

TIMMDC1

56

Q9NPL8
REKAGDVRRNLRDFE

PIBF1

146

Q8WXW3
LRAENRELGKRVQAL

CREBZF

246

Q9NS37
HEGFLLRKRELDANR

SPTBN4

2421

Q9H254
RGAFQDLKELERLRL

SLIT2

96

O94813
RKDEILGIANNRLIR

FERMT3

566

Q86UX7
QERLNFLRFLLKDGQ

USP9Y

656

O00507
VRLSRKFQGLQLERE

VPS37D

41

Q86XT2
AEQRQELLRQFRTGK

PLEC

3401

Q15149
VDQRRQGLEDFLRKV

SNX10

91

Q9Y5X0
DLRRRLEQEFQVLKG

SKOR2

951

Q2VWA4
EDQGLRKRKFDDIRI

ZNFX1

396

Q9P2E3
LFQELDRDRKRAQLI

UBE3B

626

Q7Z3V4
RLLFLRENIQRLQGD

TRH

51

P20396
FNKGDIILLRRQLDE

SH3RF2

146

Q8TEC5
LRFLLQRLEDEEARG

TARBP1

36

Q13395
LQGVILRDFQKLRDA

TRANK1

1991

O15050
EQGRKFLEEEQRLRR

TCHH

1371

Q07283
RDQLELDRLKDNLQG

TBC1D2B

481

Q9UPU7
RLQRFFLDKQRLLDR

ULK1

956

O75385
RSLRLFQKLEENGDL

WDR41

441

Q9HAD4
LKEQGLLNRERDALL

GOLGB1

2771

Q14789
RNEGLFENNKLLRRE

MORN4

111

Q8NDC4
ELRQFLGKRERVDFA

MYO1F

751

O00160
RDLEAEVFRLLKQNG

PPP1R9A

811

Q9ULJ8
LRQERAGLQDRKLDV

PPP1R9B

171

Q96SB3
RQLGDREKELIRQAA

NFKB1

186

P19838