Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	zf-RING_UBOX	TRIM25 TRIM73 TRIM74	5.81e-04	34	90	3	PF13445
Domain	Znf-RING_LisH	TRIM25 TRIM73 TRIM74	5.81e-04	34	90	3	IPR027370
Domain	EFh	MYL12A MYL9 CALML5 RASGRP2 MICU1	1.00e-03	158	90	5	SM00054
Domain	EF_Hand_1_Ca_BS	MYL12A MYL9 CALML5 RASGRP2 MICU1	1.58e-03	175	90	5	IPR018247
Domain	Kelch-typ_b-propeller	KLHL28 KBTBD13 KLHDC4	2.37e-03	55	90	3	IPR015915
Domain	EF_HAND_1	MYL12A MYL9 CALML5 RASGRP2 MICU1	3.07e-03	204	90	5	PS00018
Domain	Kelch_1	KLHL28 KBTBD13 KLHDC4	4.69e-03	70	90	3	PF01344
Domain	Kelch_1	KLHL28 KBTBD13 KLHDC4	4.69e-03	70	90	3	IPR006652
Domain	-	TRIM25 TRIM73 TRIM74	4.88e-03	71	90	3	4.10.45.10
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	KIF13B ERCC4 IGF2R WARS1 POLG HPS1 ESRP1 NSD1 PARD3 COG5 DUS3L DCX VPS13B SBNO2 RPRD1B	1.61e-07	1084	92	15	11544199
Pubmed	Attenuated NER expressions of XPF and XPC associated with smoking are involved in the recurrence of bladder cancer.	ERCC4 XPC	6.92e-06	2	92	2	25535740
Pubmed	When integrins fail to integrate.	FERMT3 RASGRP2	6.92e-06	2	92	2	19265824
Pubmed	Reduction of endoplasmic reticulum stress attenuates the defects caused by Drosophila mitofusin depletion.	KIF13B MFN2	6.92e-06	2	92	2	24469638
Pubmed	Novel variants in FERMT3 and RASGRP2-Genetic linkage in Glanzmann-like bleeding disorders.	FERMT3 RASGRP2	6.92e-06	2	92	2	31724816
Pubmed	Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship.	MUC19 GCKR SBNO2	9.78e-06	16	92	3	19068216
Pubmed	Gene structure variation in segmental duplication block C of human chromosome 7q 11.23 during primate evolution.	TRIM73 TRIM74	2.07e-05	3	92	2	26196062
Pubmed	Diphosphorylated MRLC is required for organization of stress fibers in interphase cells and the contractile ring in dividing cells.	MYL12A MYL9	2.07e-05	3	92	2	11942626
Pubmed	Inter-individual variation in nucleotide excision repair in young adults: effects of age, adiposity, micronutrient supplementation and genotype.	ERCC4 XPC	2.07e-05	3	92	2	18838045
Pubmed	TRIM50 protein regulates vesicular trafficking for acid secretion in gastric parietal cells.	TRIM73 TRIM74	2.07e-05	3	92	2	22872646
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	MYL12A TRIM25 HMGXB4 CIZ1 TOPBP1 NSD1 ALDH18A1 TMED2 XPC OLA1 PARD3 CIT NIPBL MICU1	3.83e-05	1497	92	14	31527615
Pubmed	Autophagy regulates neuronal excitability by controlling cAMP/protein kinase A signaling at the synapse.	SLC32A1 ATG16L1	4.14e-05	4	92	2	36217825
Pubmed	Breast cancer risk is not associated with polymorphic forms of xeroderma pigmentosum genes in a cohort of women from Washington County, Maryland.	ERCC4 XPC	4.14e-05	4	92	2	16823510
Pubmed	Long non-coding RNA NEAT1 mediated RPRD1B stability facilitates fatty acid metabolism and lymph node metastasis via c-Jun/c-Fos/SREBP1 axis in gastric cancer.	TRIM25 RPRD1B	4.14e-05	4	92	2	36171622
Pubmed	Mouse myosin-19 is a plus-end-directed, high-duty ratio molecular motor.	MYL12A MYL9	4.14e-05	4	92	2	24825904
Pubmed	Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes.	MYL12A MYL9 FERMT3	4.46e-05	26	92	3	23382103
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	USP5 ERCC4 TRIM25 GART TOPBP1 ALDH18A1 CALML5	4.70e-05	357	92	7	37059091
Pubmed	Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations.	POLG MFN2	6.89e-05	5	92	2	20403324
Pubmed	Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase.	TRIM73 TRIM74	6.89e-05	5	92	2	18398435
Pubmed	Polymorphisms in DNA repair genes, smoking, and pancreatic adenocarcinoma risk.	ERCC4 XPC	6.89e-05	5	92	2	18544627
Pubmed	Structural Basis for Interactions Between Contactin Family Members and Protein-tyrosine Phosphatase Receptor Type G in Neural Tissues.	PTPRG CNTN5	6.89e-05	5	92	2	27539848
Pubmed	Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice.	TRIM73 TRIM74	6.89e-05	5	92	2	20049703
Pubmed	Polymorphisms in nucleotide excision repair genes and risk of multiple primary melanoma: the Genes Environment and Melanoma Study.	ERCC4 XPC	6.89e-05	5	92	2	16258177
Pubmed	Tissue specific mutagenic and carcinogenic responses in NER defective mouse models.	ERCC4 XPC	6.89e-05	5	92	2	16769089
Pubmed	Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk.	ERCC4 POLG PTCH2 XPC	7.52e-05	84	92	4	19237606
Pubmed	Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis.	ATG16L1 MUC19 GCKR	7.63e-05	31	92	3	21072187
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	MYL12A IGF2R TRIM25 HK2 WARS1 GART RPS14 ALDH18A1 GLOD4 OLA1 CALML5 NIPBL RPRD1B	9.55e-05	1425	92	13	30948266
Pubmed	Nucleotide excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African Americans.	ERCC4 XPC	1.03e-04	6	92	2	18709642
Pubmed	Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.	POLG MFN2	1.03e-04	6	92	2	31358769
Pubmed	Polymorphisms in the DNA nucleotide excision repair genes and lung cancer risk in Xuan Wei, China.	ERCC4 XPC	1.03e-04	6	92	2	15849729
Pubmed	TRIM50 regulates Beclin 1 proautophagic activity.	TRIM73 TRIM74	1.03e-04	6	92	2	29604308
Pubmed	Interactions between ultraviolet light exposure and DNA repair gene polymorphisms may increase melanoma risk.	ERCC4 XPC	1.03e-04	6	92	2	20199546
Pubmed	Doublecortin induces mitotic microtubule catastrophe and inhibits glioma cell invasion.	KIF13B DCX	1.03e-04	6	92	2	19094064
Pubmed	Polymorphisms in nucleotide excision repair genes, smoking and breast cancer in African Americans and whites: a population-based case-control study.	ERCC4 XPC	1.03e-04	6	92	2	16399771
Pubmed	TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.	TRIM73 TRIM74	1.03e-04	6	92	2	36178239
Pubmed	Interindividual variation in nucleotide excision repair genes and risk of endometrial cancer.	ERCC4 XPC	1.03e-04	6	92	2	16284373
Pubmed	Common variations in ERCC2 are associated with response to cisplatin chemotherapy and clinical outcome in osteosarcoma patients.	ERCC4 XPC	1.03e-04	6	92	2	19434073
Pubmed	Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.	ERCC4 IGF2R MTRR XPC NLRP5	1.17e-04	179	92	5	19074885
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	MYL12A ATG16L1 USP5 HK2 WARS1 MYL9 GART RPS14 MTRR OLA1 COG5 DUS3L RPRD1B	1.18e-04	1455	92	13	22863883
Pubmed	Polymorphisms in DNA repair and one-carbon metabolism genes and overall survival in diffuse large B-cell lymphoma and follicular lymphoma.	ERCC4 MTRR XPC	1.20e-04	36	92	3	18830263
Pubmed	Multiple active conformers of mouse ornithine decarboxylase.	GART ODC1	1.44e-04	7	92	2	8328969
Pubmed	Polymorphisms in DNA damage response genes and head and neck cancer risk.	ERCC4 XPC	1.44e-04	7	92	2	20429839
Pubmed	DNA repair gene variants associated with benign breast disease in high cancer risk women.	ERCC4 XPC	1.44e-04	7	92	2	19124519
Pubmed	Myosin regulatory light chains are required to maintain the stability of myosin II and cellular integrity.	MYL12A MYL9	1.44e-04	7	92	2	21126233
Pubmed	Nucleotide excision repair gene polymorphisms and risk of advanced colorectal adenoma: XPC polymorphisms modify smoking-related risk.	ERCC4 XPC	1.44e-04	7	92	2	16492920
Pubmed	Nucleotide excision repair pathway genes and oral premalignant lesions.	ERCC4 XPC	1.44e-04	7	92	2	17575242
Pubmed	Chamber specification of atrial myosin light chain-2 expression precedes septation during murine cardiogenesis.	MYL12A MYL9	1.44e-04	7	92	2	8207020
Pubmed	Genetic variation in the nucleotide excision repair pathway and bladder cancer risk.	ERCC4 XPC	1.44e-04	7	92	2	16537713
Pubmed	A summary of mutations in the UV-sensitive disorders: xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy.	ERCC4 XPC	1.44e-04	7	92	2	10447254
Pubmed	Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression.	TRIM73 TRIM74	1.44e-04	7	92	2	26025256
Pubmed	Analysis of 39 Crohn's disease risk loci in Swedish inflammatory bowel disease patients.	ATG16L1 GCKR SBNO2	1.53e-04	39	92	3	19760754
Pubmed	Gene-environment interaction involved in oral carcinogenesis: molecular epidemiological study for metabolic and DNA repair gene polymorphisms.	ERCC4 XPC	1.92e-04	8	92	2	16393248
Pubmed	Neurotrophin receptor-mediated death of misspecified neurons generated from embryonic stem cells lacking Pax6.	SLC32A1 DCX	1.92e-04	8	92	2	18371392
Pubmed	Distinct Roles of Smooth Muscle and Non-muscle Myosin Light Chain-Mediated Smooth Muscle Contraction.	MYL12A MYL9	1.92e-04	8	92	2	33424621
Pubmed	Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.	TRIM25 WARS1 GART ALDH18A1	1.92e-04	107	92	4	30995489
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	ALKBH1 USP5 TRIM25 HK2 WARS1 GART RPS14 ALDH18A1 XPC PARD3 DUS3L NIPBL	2.35e-04	1353	92	12	29467282
Pubmed	Epitranscriptomic regulation of cortical neurogenesis via Mettl8-dependent mitochondrial tRNA m3C modification.	METTL8 DCX	2.46e-04	9	92	2	36764294
Pubmed	Genetic variation in DNA repair genes and prostate cancer risk: results from a population-based study.	ERCC4 XPC	2.46e-04	9	92	2	19902366
Pubmed	Xeroderma Pigmentosum	ERCC4 XPC	2.46e-04	9	92	2	20301571
Pubmed	Multiplexed peroxidase-based electron microscopy labeling enables simultaneous visualization of multiple cell types.	SLC32A1 MRGPRX2	2.46e-04	9	92	2	30886406
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	USP5 TRIM25 HK2 HMGXB4 NIPBL EML3	2.59e-04	332	92	6	32786267
Pubmed	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	ATG16L1 MUC19 GCKR SBNO2	2.62e-04	116	92	4	21102463
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	USP5 TRIM25 WARS1 GART RPS14 MUC19 ALDH18A1 TMED2 OLA1	2.91e-04	807	92	9	30575818
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	MYL12A USP5 ERCC4 WARS1 KLHL28 UBXN6 OLA1	2.95e-04	481	92	7	28190767
Pubmed	Single-nucleotide polymorphisms in DNA-repair genes and cutaneous melanoma.	ERCC4 XPC	3.07e-04	10	92	2	20601096
Pubmed	Nogo-a regulates neural precursor migration in the embryonic mouse cortex.	LINGO1 DCX	3.07e-04	10	92	2	20093372
Pubmed	ERCC1 haplotypes modify bladder cancer risk: a case-control study.	ERCC4 XPC	3.07e-04	10	92	2	20061190
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP5 IGF2R WARS1 GART RPS14 NSD1 ALDH18A1 NIPBL	3.45e-04	653	92	8	22586326
Pubmed	Atg9a deficiency causes axon-specific lesions including neuronal circuit dysgenesis.	SLC32A1 ATG16L1	3.75e-04	11	92	2	28513333
Pubmed	Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND.	MYL12A MYL9	3.75e-04	11	92	2	9171826
Pubmed	Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome.	ERCC4 XPC	3.75e-04	11	92	2	11259578
Pubmed	Polymorphism in nucleotide excision repair gene XPC correlates with bleomycin-induced chromosomal aberrations.	ERCC4 XPC	3.75e-04	11	92	2	17685459
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	IGF2R MYL9 GART ALDH18A1 TMED2 GLOD4 FERMT3	3.86e-04	503	92	7	36217030
Pubmed	Telophase correction refines division orientation in stratified epithelia.	MYL9 PARD3	4.49e-04	12	92	2	31833472
Pubmed	Comprehensive analysis of DNA repair gene variants and risk of meningioma.	ERCC4 POLG XPC	4.73e-04	57	92	3	18270339
Pubmed	Subtractive hybridisation screen identifies genes regulated by glucose deprivation in human neuroblastoma cells.	MYL12A ODC1	5.30e-04	13	92	2	17719568
Pubmed	Multiple loci influencing hippocampal degeneration identified by genome scan.	METTL8 VPS13B	5.30e-04	13	92	2	22745009
Pubmed	Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk.	ERCC4 XPC	5.30e-04	13	92	2	18701435
Pubmed	Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer.	GART MTRR	5.30e-04	13	92	2	19936946
Pubmed	Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain.	USP5 UBXN6 MFN2 NIPBL	5.78e-04	143	92	4	32560809
Pubmed	Pigmentation-related genes and their implication in malignant melanoma susceptibility.	HPS1 VPS13B	6.17e-04	14	92	2	19320733
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	IGF2R WARS1 MYL9 GART RPS14 MFN2 ALDH18A1 TMED2 NAA40 NIPBL RPRD1B	6.30e-04	1297	92	11	33545068
Pubmed	Direct and indirect control of mitogen-activated protein kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/RAF1 kinase, by the deubiquitylating enzyme USP15.	USP5 TRIM25 TRIM74	6.34e-04	63	92	3	23105109
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	ATG16L1 USP5 HK2 WARS1 CIZ1 OLA1	6.92e-04	400	92	6	35013556
Pubmed	SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.	ERCC4 TRIM25 POLG ALDH18A1	6.92e-04	150	92	4	30154076
Pubmed	The interactome of the prostate-specific protein Anoctamin 7.	ALDH18A1 XPC NIPBL	6.95e-04	65	92	3	32176628
Pubmed	Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs.	SLC32A1 DCX	7.11e-04	15	92	2	23064108
Pubmed	Expression of the Neuronal tRNA n-Tr20 Regulates Synaptic Transmission and Seizure Susceptibility.	SLC32A1 ATG16L1	7.11e-04	15	92	2	32853550
Pubmed	Scribble mutation disrupts convergent extension and apical constriction during mammalian neural tube closure.	MYL9 PARD3	7.11e-04	15	92	2	34029538
Pubmed	Differential genomic imprinting regulates paracrine and autocrine roles of IGF2 in mouse adult neurogenesis.	IGF2R DCX	7.11e-04	15	92	2	26369386
Pubmed	PML Recruits TET2 to Regulate DNA Modification and Cell Proliferation in Response to Chemotherapeutic Agent.	MYL12A MYL9 CALML5	7.59e-04	67	92	3	29735542
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	HK2 CDK5RAP1 MFN2 ALDH18A1 TMED2 NAA40 OLA1 COG5 NIPBL RPRD1B MICU1	7.60e-04	1327	92	11	32694731
Pubmed	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.	MYL12A WARS1 GART RPS14 OLA1 FMNL1 FERMT3	7.66e-04	565	92	7	20458337
Pubmed	Apical Restriction of the Planar Cell Polarity Component VANGL in Pancreatic Ducts Is Required to Maintain Epithelial Integrity.	MYL9 PARD3	8.11e-04	16	92	2	32460029
Pubmed	GATA4 transcription factor is required for ventral morphogenesis and heart tube formation.	MYL12A MYL9	8.11e-04	16	92	2	9136932
Pubmed	Pdx1 regulates pancreas tubulogenesis and E-cadherin expression.	MYL9 PARD3	8.11e-04	16	92	2	26657766
Pubmed	Intact lipid rafts regulate HIV-1 Tat protein-induced activation of the Rho signaling and upregulation of P-glycoprotein in brain endothelial cells.	MYL12A MYL9	8.11e-04	16	92	2	19794400
Pubmed	The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome.	TRIM73 TRIM74	8.11e-04	16	92	2	22792322
Pubmed	Influence of polymorphisms in xenobiotic-metabolizing genes and DNA-repair genes on diepoxybutane-induced SCE frequency.	ERCC4 XPC	9.17e-04	17	92	2	17078101
Pubmed	A comprehensive family-based replication study of schizophrenia genes.	CLC NOTCH4	9.17e-04	17	92	2	23894747
Interaction	PRR14L interactions	TRIM25 UBXN6 PPP4R1L NAA40 CIT	5.88e-06	59	88	5	int:PRR14L
GeneFamily	WD repeat domain containing\|Xeroderma pigmentosum complementation groups\|Nucleotide excision repair	ERCC4 XPC	2.99e-04	8	60	2	1125
GeneFamily	EF-hand domain containing	MYL12A MYL9 CALML5 RASGRP2 MICU1	7.92e-04	219	60	5	863
GeneFamily	Myosin light chains\|EF-hand domain containing	MYL12A MYL9	9.61e-04	14	60	2	657
GeneFamily	WD repeat domain containing	ATG16L1 DAW1 FBXW4 EML3 WDFY2	1.75e-03	262	60	5	362
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HMCN2 LINGO1 CNTN5 PAPLN	2.00e-03	161	60	4	593
GeneFamily	NLR family	CIITA NLRP5	3.09e-03	25	60	2	666
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM25 TRIM73 TRIM74	3.87e-03	95	60	3	59
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-skeletal_muscle_satellite_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYL12A PIK3C2G OTOGL RPS14 ODC1 SBNO2	1.66e-06	174	92	6	f230d23618a6487f2664efb2c677e0a4559e2bf4
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KIF13B OR6C2 ESRP1 NRSN1 PARD3 CIT	1.90e-06	178	92	6	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
Drug	N-acetoxy-2-acetylaminofluorene	ERCC4 POLG XPC C8G DCX	3.60e-07	37	91	5	CID000022469
Drug	Tubocurarine chloride pentahydrate (+) [6989-98-6]; Down 200; 5.2uM; HL60; HG-U133A	HPS1 FBXW4 MTRR ALDH18A1 TMED2 NIPBL EML3 VPS13B	1.35e-06	199	91	8	1738_DN
Drug	8-oxoguanine	IGF2R TRIM25 POLG XPC DCX	5.34e-06	63	91	5	CID000065154
Drug	first rate	HK2 WARS1 ALAS1	9.96e-06	11	91	3	CID000086453
Drug	Acyclovir [59277-89-3]; Up 200; 17.8uM; PC3; HG-U133A	USP5 MYL9 NSD1 MTRR TMED2 XPC SBNO2	1.34e-05	195	91	7	1960_UP
Drug	Ranitidine hydrochloride [66357-59-3]; Down 200; 11.4uM; PC3; HT_HG-U133A	USP5 POLG GART PARD3 EML3 VPS13B SBNO2	1.53e-05	199	91	7	6324_DN
Disease	leukocyte adhesion deficiency 3 (implicated_via_orthology)	FERMT3 RASGRP2	9.41e-06	2	91	2	DOID:0110912 (implicated_via_orthology)
Disease	xeroderma pigmentosum (is_implicated_in)	ERCC4 XPC	1.40e-04	6	91	2	DOID:0050427 (is_implicated_in)
Disease	xeroderma pigmentosum (implicated_via_orthology)	ERCC4 XPC	1.40e-04	6	91	2	DOID:0050427 (implicated_via_orthology)
Disease	Inflammatory Bowel Diseases	ATG16L1 HPS1 MUC19	1.73e-04	35	91	3	C0021390
Disease	Xeroderma pigmentosum	ERCC4 XPC	3.34e-04	9	91	2	cv:C0043346
Disease	Adenocarcinoma of lung (disorder)	HK2 GART ALDH18A1 ROS1 XPC	4.52e-04	206	91	5	C0152013
Disease	Basal cell carcinoma	ERCC4 XPC	5.08e-04	11	91	2	C0007117
Disease	femoral neck bone geometry	HK2 NSD1	8.36e-04	14	91	2	EFO_0004511
Disease	multiple sclerosis (is_implicated_in)	CIITA POLG NOTCH4	1.51e-03	73	91	3	DOID:2377 (is_implicated_in)
Disease	Hemorrhage	HPS1 FERMT3	1.72e-03	20	91	2	C0019080
Disease	citrulline measurement	HMCN2 ALDH18A1	1.72e-03	20	91	2	EFO_0009777
Disease	saturated fatty acids to total fatty acids percentage	GCKR NOTCH4	1.90e-03	21	91	2	EFO_0022305
Disease	type 2 diabetes mellitus (is_implicated_in)	IGF2R HK2 PIK3C2G GCKR	1.97e-03	171	91	4	DOID:9352 (is_implicated_in)
Disease	C-peptide measurement	MUC19 GCKR	2.09e-03	22	91	2	EFO_0005187
Disease	remission, hepatitis C virus infection	PARD3 NOTCH4	2.28e-03	23	91	2	EFO_0003047, EFO_0009785
Disease	serum iron measurement	CNTN5 ATP13A5 NOTCH4	2.41e-03	86	91	3	EFO_0006332
Disease	carnosine measurement	COG5 CNDP1	2.48e-03	24	91	2	EFO_0010470
Disease	cholelithiasis	NSD1 GCKR VPS13B	2.58e-03	88	91	3	EFO_0004799
Disease	inflammatory bowel disease	ATG16L1 MUC19 GCKR CIT NOTCH4 SBNO2	2.69e-03	449	91	6	EFO_0003767
Disease	alpha-linolenic acid measurement	LCT NLRP5	2.69e-03	25	91	2	EFO_0007759
Disease	macular telangiectasia type 2	GCKR FBN3	2.91e-03	26	91	2	EFO_1002009
Disease	Micronuclei, Chromosome-Defective	ERCC4 XPC	2.91e-03	26	91	2	C1449861
Disease	Micronuclei, Genotoxicant-Induced	ERCC4 XPC	2.91e-03	26	91	2	C1449862

Protein segments in the cluster

Peptide	Gene	Start	Entry
HGFSEDFEEVQRCTA	PTPRG	846	P23470
CVAFFVEDSILQNHE	ATP13A5	1126	Q4VNC0
GFCEAADQFHVLDEV	C8G	186	P07360
SQACELHVAGFDFEV	B4GAT1	351	O43505
EQVAAACGFEDFRAE	ALKBH1	201	Q13686
FEELEAQDGFLHSTC	CIITA	501	P33076
CVFDAHDGEVNAVQF	ATG16L1	316	Q676U5
HQCEDIFGVQLEGAF	DUS3L	356	Q96G46
FVVTHNGDCVDFDEC	FBN3	1876	Q75N90
AFRAFDQDGDGHITV	CALML5	86	Q9NZT1
DFEVRSLVGCGHFAE	CIT	96	O14578
FEEEGGHFESIRAQA	CNTN5	616	O94779
TATAEEVVAFFGQHC	ESRP1	336	Q6NXG1
VIRNAFACFDEEATG	MYL12A	101	P19105
LHFENFTCVDDADVD	NSD1	151	Q96L73
GLQLEFCDSNAIDHF	OR6C2	161	Q9NZP2
ACDGIFHLTRAFEDD	OLA1	116	Q9NTK5
IGRLEEFFQDVNTCH	PIK3C2G	861	O75747
VESVFRNFDVDGDGH	RASGRP2	431	Q7LDG7
ELCDVAHEFGAITFV	ALAS1	396	P13196
HEICFVGDEAFRELS	GLOD4	266	Q9HC38
AQFECVVSNEVGEAH	HMCN2	3826	Q8NDA2
GNCHFDFAQEILFVD	KATNIP	1351	O60303
AFCESEFAVNGIVHD	C17orf58	206	Q2M2W7
EICEQAVVHGFSADL	MTRR	21	Q9UBK8
GDELFDHIVQCIADF	HK2	571	P52789
HVCDVVFALFDCDGN	MICU1	411	Q9BPX6
AFACFDEEASGFIHE	MYL9	106	P24844
FCRHCIESGGDFNIE	MUC19	506	Q7Z5P9
EAFGEADFVVVDTHA	NRSN1	91	Q8IZ57
TVGALCRHFDFDLED	NIPBL	2146	Q6KC79
QVLEGHTDEIFSCAF	DAW1	381	Q8N136
EEFAIDGRFCISIHD	POLG	1121	P54098
EESDIVFHFQVCFGR	CLC	46	Q05315
VENDAIGDVACDSYH	LCT	1416	P09848
VDEGHTVQFVCRADG	LINGO1	436	Q96FE5
DAFHCLFETQDKEFV	NLRP5	686	P59047
DCFDGDHTFEDIGLA	HMGXB4	11	Q9UGU5
FSHFRFDVECGDEVL	NAA40	121	Q86UY6
NCFLRVEGTDGHEAF	MFN2	131	O95140
DKLCADFQEDIEFHF	MFN2	531	O95140
TAEFFLQHVDSACVF	ALDH18A1	706	P54886
GLQLDFCAANTVDHF	OR6C74	161	A6NCV1
GVECIHTFGADFRDV	GCKR	346	Q14397
HFECLDFVFDNTEAI	COG5	661	Q9UP83
AVCQTEEFFELTHAD	KLHL28	166	Q9NXS3
VCDEDKFRHNEFIGE	DOC2B	216	Q14184
VTCLHDFFGDDDVFI	DCX	236	O43602
LGVFAGHDEDVCHFV	FBXW4	156	P57775
AAFDNFKEVCGEQHR	FMNL1	291	O95466
NHQTLFFGGVCDEEE	KLHDC4	306	Q8TBB5
DQGAFLCVVDDSNEH	EML3	371	Q32P44
FGECLFIAINGDHTE	HPS1	86	Q92902
RATQCFAFVHDVCDD	METTL8	246	Q9H825
NFGDICHAVGQEATE	PPP4R1L	186	Q9P1A2
NEEFDCHFLDEGFTA	ODC1	6	P11926
TCEVGEFTAIDHNFQ	OTOGL	2086	Q3ZCN5
AEIQDFHRTFGCDDE	PARD3	1081	Q8TEW0
HCNEFSVNITEDFIE	KIF13B	926	Q9NQT8
GTADAFIVRFVCNDD	IGF2R	1031	P11717
NVDGDGNFCDSEFHL	MINDY2	481	Q8NBR6
EHRQFGGNCDVDVSF	WARS1	386	P23381
HIFTFDEEATCTDEG	SPATA48	206	A4D263
VDAFSHVAREADEGC	RPRD1B	86	Q9NQG5
ADFVEAIEGARAACA	PTCH2	921	Q9Y6C5
VAEGENVFGVCHIFA	RPS14	21	P62263
CGEAFEGVIVFDECH	SBNO2	376	Q9Y2G9
EDADERGVAVHFAVC	PPP1R3G	316	B7ZBB8
GVDVHFSGAVDCFRQ	SLC25A43	241	Q8WUT9
DIAEVDHSEGCFRQG	MRGPRX2	306	Q96LB1
FEGHACERDVNECFQ	NOTCH4	186	Q99466
VFHHVNAYEEDGCIV	BCO1	306	Q9HAY6
VEVKCRDQDFHSGTF	CNDP1	251	Q96KN2
QDEDHFITVDAVGCF	CIZ1	726	Q9ULV3
DFIAGFCGETEEDHV	CDK5RAP1	441	Q96SZ6
ECVLEQFGNEDHHEF	TRIM74	226	Q86UV6
ERINCLEGTHEFFEA	UBXN6	206	Q9BZV1
FLCNDLGEDFTQHIA	ZNF596	111	Q8TC21
GFEFEVRVCDSCHEA	WDFY2	336	Q96P53
DGARDFRAEQCAEFD	PAPLN	81	O95428
VFHSAALFICDGERE	KBTBD13	121	C9JR72
LNCDHGFVIFFAVAD	TRIM25	581	Q14258
FCVEVNTAFEDFAHV	PRPF40B	571	Q6NWY9
NEFIVGCDLSHIEEF	ROS1	526	P08922
IEFDEHINVAFSCVS	FERMT3	611	Q86UX7
CTVHFVAEDVDAGQI	GART	941	P22102
DAHAEECFFERVTSG	TMED2	26	Q15363
GQDGQAVVREHFDCL	VPS13B	2751	Q7Z7G8
ECVLEQFGNEDHHEF	TRIM73	226	Q86UV7
ATDEEAVGFAHCDDL	SLC32A1	36	Q9H598
DNAVAFDTGFCHVER	ERCC4	166	Q92889
LDIDCVQAITGFDFH	XPC	786	Q01831
ACRTAGHFVQEEDYE	TOPBP1	1336	Q92547
AGDRVHKDECAFSFD	USP5	21	P45974