Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

KAT7 KAT6B CREBBP EP300

3.66e-0715834GO:0010484
GeneOntologyMolecularFunctionexogenous lipid antigen binding

CD1A CD1B CD1D

6.88e-075833GO:0030884
GeneOntologyMolecularFunctionendogenous lipid antigen binding

CD1A CD1B CD1D

6.88e-075833GO:0030883
GeneOntologyMolecularFunctionlipid antigen binding

CD1A CD1B CD1D

1.37e-066833GO:0030882
GeneOntologyMolecularFunctionN-acyltransferase activity

KAT7 NMT2 KAT6B NMT1 CREBBP EP300

4.21e-06102836GO:0016410
GeneOntologyMolecularFunctionlipopeptide binding

CD1A CD1B CD1D

8.14e-0610833GO:0071723
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

1.71e-052832GO:0120300
GeneOntologyMolecularFunctionglycylpeptide N-tetradecanoyltransferase activity

NMT2 NMT1

1.71e-052832GO:0004379
GeneOntologyMolecularFunctionpeptidyl-lysine N6-myristoyltransferase activity

NMT2 NMT1

1.71e-052832GO:0018030
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

1.71e-052832GO:0044017
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

5.11e-053832GO:0043993
GeneOntologyMolecularFunctionhistone acetyltransferase activity

KAT7 KAT6B CREBBP EP300

5.98e-0551834GO:0004402
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

KAT7 NMT2 KAT6B NMT1 ACSM2A CREBBP EP300

6.02e-05238837GO:0016747
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

KAT7 KAT6B CREBBP EP300

8.05e-0555834GO:0061733
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

KAT7 KAT6B CREBBP EP300

1.13e-0460834GO:0034212
GeneOntologyMolecularFunctionN-acetyltransferase activity

KAT7 KAT6B CREBBP EP300

3.13e-0478834GO:0008080
GeneOntologyMolecularFunctionbHLH transcription factor binding

CREBBP EP300 SMAD3

4.86e-0437833GO:0043425
GeneOntologyMolecularFunctionhistone H3K14 acetyltransferase activity

KAT7 KAT6B

6.03e-049832GO:0036408
GeneOntologyMolecularFunctionmedium-chain fatty acid-CoA ligase activity

AACS ACSM2A

9.16e-0411832GO:0031956
GeneOntologyMolecularFunctionmyristoyltransferase activity

NMT2 NMT1

9.16e-0411832GO:0019107
GeneOntologyMolecularFunctionacetyltransferase activity

KAT7 KAT6B CREBBP EP300

9.31e-04104834GO:0016407
GeneOntologyMolecularFunctionantigen binding

CD1A CD1B CD1D FCN3 EP300

1.18e-03190835GO:0003823
GeneOntologyMolecularFunctionphosphotyrosine residue binding

GRAPL VAV1 GRAP

1.25e-0351833GO:0001784
GeneOntologyMolecularFunctionG protein-coupled purinergic nucleotide receptor activity

P2RY6 P2RY11

1.29e-0313832GO:0045028
GeneOntologyMolecularFunctionacyltransferase activity

KAT7 RAG2 NMT2 NEURL1 KAT6B NMT1 ACSM2A CREBBP NEURL4 EP300

1.38e-037758310GO:0016746
GeneOntologyMolecularFunctiontranscription coactivator binding

CREBBP EP300 SMAD3

1.47e-0354833GO:0001223
GeneOntologyMolecularFunctionpre-mRNA intronic binding

PRPF8 EP300

1.50e-0314832GO:0097157
GeneOntologyMolecularFunctionmodification-dependent protein binding

RAG2 TNIP1 PRPF8 EP300 VAV1

1.68e-03206835GO:0140030
GeneOntologyMolecularFunctiontransmembrane-ephrin receptor activity

EFNA4 EPHA5

1.73e-0315832GO:0005005
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

EFNA4 MERTK EPHA5

2.51e-0365833GO:0004714
GeneOntologyMolecularFunctionephrin receptor activity

EFNA4 EPHA5

2.79e-0319832GO:0005003
GeneOntologyMolecularFunctionprotein phosphorylated amino acid binding

GRAPL VAV1 GRAP

2.98e-0369833GO:0045309
GeneOntologyMolecularFunctionnuclear glucocorticoid receptor binding

EP300 SMAD3

3.09e-0320832GO:0035259
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

TNK1 EFNA4 MERTK EPHA5

3.14e-03145834GO:0004713
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

CREBBP EP300

3.41e-0321832GO:0042975
GeneOntologyMolecularFunctionnucleotide receptor activity

P2RY6 P2RY11

3.74e-0322832GO:0016502
GeneOntologyMolecularFunctionpurinergic nucleotide receptor activity

P2RY6 P2RY11

3.74e-0322832GO:0001614
GeneOntologyMolecularFunctionhistone H4 acetyltransferase activity

KAT7 EP300

4.08e-0323832GO:0010485
GeneOntologyMolecularFunctionchromatin DNA binding

H1-9P CREBBP EP300 SMAD3

5.19e-03167834GO:0031490
GeneOntologyMolecularFunctionfatty acid ligase activity

AACS ACSM2A

5.20e-0326832GO:0015645
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

EFNA4 MERTK EPHA5

5.35e-0385833GO:0019199
GeneOntologyMolecularFunctionSMAD binding

CREBBP EP300 SMAD3

5.53e-0386833GO:0046332
GeneOntologyMolecularFunctionCoA-ligase activity

AACS ACSM2A

5.60e-0327832GO:0016405
GeneOntologyMolecularFunctionpeptidase activity

ACR ATG4C PAPPA PRSS58 PRPF8 F2 AGBL1 PCSK9

5.79e-03654838GO:0008233
GeneOntologyMolecularFunctionkinase binding

TRIB3 SH2B3 GRAPL TNIP1 ZFYVE26 MYOM2 MVP RHOF EP300 SMAD3

6.79e-039698310GO:0019900
GeneOntologyMolecularFunctionacid-thiol ligase activity

AACS ACSM2A

7.34e-0331832GO:0016878
GeneOntologyMolecularFunctionserine-type endopeptidase activity

ACR PRSS58 F2 PCSK9

8.14e-03190834GO:0004252
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor binding

SACS PCSK9

8.79e-0334832GO:0050750
GeneOntologyBiologicalProcessantigen processing and presentation, endogenous lipid antigen via MHC class Ib

CD1A CD1B CD1D

6.02e-075823GO:0048006
GeneOntologyBiologicalProcessantigen processing and presentation, exogenous lipid antigen via MHC class Ib

CD1A CD1B CD1D

2.10e-067823GO:0048007
GeneOntologyBiologicalProcessantigen processing and presentation of lipid antigen via MHC class Ib

CD1A CD1B CD1D

2.10e-067823GO:0048003
GeneOntologyBiologicalProcessN-terminal protein amino acid modification

NMT2 NMT1 CREBBP EP300

5.11e-0629824GO:0031365
GeneOntologyBiologicalProcessN-terminal peptidyl-glycine N-myristoylation

NMT2 NMT1

1.56e-052822GO:0018008
GeneOntologyBiologicalProcesspeptidyl-glycine modification

NMT2 NMT1

4.67e-053822GO:0018201
GeneOntologyBiologicalProcessprotein acylation

KAT7 NMT2 NMT1 CREBBP EP300

7.10e-05108825GO:0043543
GeneOntologyBiologicalProcessregulation of protein localization to nucleus

KAT7 EPM2A F2 CREBBP EP300 SMAD3

7.26e-05176826GO:1900180
GeneOntologyBiologicalProcesspositive regulation of protein localization to nucleus

KAT7 F2 CREBBP EP300 SMAD3

9.18e-05114825GO:1900182
GeneOntologyBiologicalProcessN-terminal protein myristoylation

NMT2 NMT1

9.32e-054822GO:0006499
GeneOntologyBiologicalProcessprotein myristoylation

NMT2 NMT1

9.32e-054822GO:0018377
GeneOntologyBiologicalProcessN-terminal peptidyl-lysine acetylation

CREBBP EP300

9.32e-054822GO:0018076
GeneOntologyBiologicalProcessantigen processing and presentation via MHC class Ib

CD1A CD1B CD1D

1.31e-0425823GO:0002475
GeneOntologyBiologicalProcesspeptidyl-lysine acetylation

KAT7 CREBBP EP300

1.85e-0428823GO:0018394
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous antigen

CD1A CD1B CD1D

2.76e-0432823GO:0019883
GeneOntologyBiologicalProcesspositive regulation of leukocyte mediated cytotoxicity

CD1A CD1B CD1D VAV1

2.78e-0479824GO:0001912
GeneOntologyBiologicalProcessN-terminal protein lipidation

NMT2 NMT1

3.24e-047822GO:0006498
GeneOntologyCellularComponentacetyltransferase complex

KAT7 PDHB KAT6B CREBBP EP300

7.39e-05109835GO:1902493
GeneOntologyCellularComponentH3 histone acetyltransferase complex

KAT7 KAT6B

4.29e-048832GO:0070775
GeneOntologyCellularComponenthistone acetyltransferase complex

KAT7 KAT6B CREBBP EP300

5.37e-0494834GO:0000123
GeneOntologyCellularComponentprotein acetyltransferase complex

KAT7 KAT6B CREBBP EP300

7.86e-04104834GO:0031248
GeneOntologyCellularComponentexternal side of plasma membrane

CD1A CD1B CD1D LCT F2 FCN3 PCSK9 EPHA5

1.06e-03519838GO:0009897
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

3.58e-052312HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

3.58e-052312HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

3.58e-052312HP:0001042
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

1.07e-043312HP:0008752
HumanPhenoPhobia

CREBBP EP300

1.07e-043312HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

1.07e-043312HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

1.07e-043312HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

1.07e-043312HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

1.07e-043312HP:0005895
HumanPhenoTrichiasis

CREBBP EP300

2.13e-044312HP:0001128
HumanPhenoVisceral hemangioma

CREBBP EP300

2.13e-044312HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

2.13e-044312HP:0011087
HumanPhenoWidened distal phalanges

CREBBP EP300

2.13e-044312HP:0006200
HumanPhenoVascular ring

CREBBP EP300

2.13e-044312HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

2.13e-044312HP:0031207
HumanPhenoAbnormality of tear glands or tear production

ELP1 KAT6B GMPPA CREBBP EP300 IGSF3

2.92e-04156316HP:0000521
HumanPhenoPapillary cystadenoma of the epididymis

CREBBP EP300

3.54e-045312HP:0009715
HumanPhenoSupernumerary cusp

CREBBP EP300

3.54e-045312HP:0033777
HumanPhenoEpididymal neoplasm

CREBBP EP300

3.54e-045312HP:0030421
DomainMHC_I_3

CD1A CD1B CD1D

1.56e-066813PF16497
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

1.86e-052812IPR014744
DomainHAT_KAT11

CREBBP EP300

1.86e-052812PF08214
DomainKIX

CREBBP EP300

1.86e-052812PS50952
DomainZnF_TAZ

CREBBP EP300

1.86e-052812SM00551
DomainCBP_P300_HAT

CREBBP EP300

1.86e-052812IPR031162
DomainDUF902

CREBBP EP300

1.86e-052812PF06001
DomainMyristoylCoA_TrFase_C

NMT2 NMT1

1.86e-052812IPR022677
DomainMyristoylCoA_TrFase_N

NMT2 NMT1

1.86e-052812IPR022676
DomainMyristoylCoA_TrFase_CS

NMT2 NMT1

1.86e-052812IPR022678
Domain-

CREBBP EP300

1.86e-0528121.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

1.86e-052812IPR010303
Domain-

CREBBP EP300

1.86e-0528121.10.1630.10
DomainCreb_binding

CREBBP EP300

1.86e-052812PF09030
DomainNMT_1

NMT2 NMT1

1.86e-052812PS00975
DomainNMT_2

NMT2 NMT1

1.86e-052812PS00976
Domain-

CREBBP EP300

1.86e-0528121.10.246.20
Domainzf-TAZ

CREBBP EP300

1.86e-052812PF02135
DomainZF_TAZ

CREBBP EP300

1.86e-052812PS50134
DomainMyristoylCoA_TrFase

NMT2 NMT1

1.86e-052812IPR000903
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

1.86e-052812IPR013178
DomainNMT_C

NMT2 NMT1

1.86e-052812PF02799
DomainNMT

NMT2 NMT1

1.86e-052812PF01233
DomainKAT11

CREBBP EP300

1.86e-052812SM01250
DomainZnf_TAZ

CREBBP EP300

1.86e-052812IPR000197
DomainKIX_dom

CREBBP EP300

1.86e-052812IPR003101
DomainKIX

CREBBP EP300

1.86e-052812PF02172
DomainCBP_P300_HAT

CREBBP EP300

1.86e-052812PS51727
Domain-

KAT7 NMT2 KAT6B NMT1

2.66e-05408143.40.630.30
DomainAcyl_CoA_acyltransferase

KAT7 NMT2 KAT6B NMT1

4.27e-0545814IPR016181
Domain-

CD1A CD1B CD1D

1.49e-04248133.30.500.10
DomainMHC_I-like_Ag-recog

CD1A CD1B CD1D

1.49e-0424813IPR011161
DomainNEUZ

NEURL1 NEURL4

1.84e-045812SM00588
DomainMOZ_SAS

KAT7 KAT6B

1.84e-045812PF01853
DomainNHR

NEURL1 NEURL4

1.84e-045812PS51065
DomainHAT_MYST-type

KAT7 KAT6B

1.84e-045812IPR002717
DomainNeuralized

NEURL1 NEURL4

1.84e-045812PF07177
DomainNHR_dom

NEURL1 NEURL4

1.84e-045812IPR006573
DomainMYST_HAT

KAT7 KAT6B

1.84e-045812PS51726
DomainNuc_rcpt_coact

CREBBP EP300

2.76e-046812IPR009110
DomainMHC_I/II-like_Ag-recog

CD1A CD1B CD1D

5.94e-0438813IPR011162
DomainSH2

SH2B3 GRAPL VAV1 GRAP

9.74e-04101814PF00017
DomainSH2

SH2B3 GRAPL VAV1 GRAP

1.34e-03110814SM00252
DomainSH2

SH2B3 GRAPL VAV1 GRAP

1.38e-03111814PS50001
DomainLinker_histone

H1-9P KAT6B

1.40e-0313812PF00538
DomainSH2

SH2B3 GRAPL VAV1 GRAP

1.43e-03112814IPR000980
Domain-

SH2B3 GRAPL VAV1 GRAP

1.43e-031128143.30.505.10
DomainHistone_H1/H5_H15

H1-9P KAT6B

1.63e-0314812IPR005818
DomainC1-set

CD1A CD1B CD1D

1.66e-0354813PF07654
DomainIGc1

CD1A CD1B CD1D

1.85e-0356813SM00407
DomainIg_C1-set

CD1A CD1B CD1D

2.04e-0358813IPR003597
DomainSMAD_dom-like

DUSP15 SMAD3

2.14e-0316812IPR017855
Domain-

DUSP15 SMAD3

2.14e-03168122.60.200.10
DomainZZ

CREBBP EP300

2.72e-0318812PF00569
DomainZF_ZZ_2

CREBBP EP300

2.72e-0318812PS50135
DomainZF_ZZ_1

CREBBP EP300

2.72e-0318812PS01357
DomainZnf_ZZ

CREBBP EP300

3.03e-0319812IPR000433
DomainZnF_ZZ

CREBBP EP300

3.03e-0319812SM00291
DomainZnf_FYVE_PHD

RAG2 PHF14 ZFYVE26 KAT6B

3.83e-03147814IPR011011
DomainCupredoxin

EFNA4 PRPF8

4.06e-0322812IPR008972
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

ARNT CREBBP EP300

1.12e-0511593M26924
PathwayREACTOME_SIGNALING_BY_SCF_KIT

SH2B3 GRAPL VAV1 GRAP

1.65e-0537594MM14564
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300 SMAD3

4.54e-0517593MM1509
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300 SMAD3

6.43e-0519593M18933
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300 SMAD3

7.55e-0520593M27881
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300 SMAD3

1.01e-0422593MM1443
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300 SMAD3

1.16e-0423593M2821
PathwayPID_HIF1_TFPATHWAY

ARNT CREBBP EP300 SMAD3

1.64e-0466594M255
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

1.71e-045592MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

1.71e-045592M48020
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

1.71e-045592M48023
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

1.71e-045592M27228
PathwayWP_KIT_RECEPTOR_SIGNALING_PATHWAY

GRAPL EP300 VAV1 GRAP

2.18e-0471594MM15947
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

2.56e-046592M22062
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

ARNT EP300

2.56e-046592MM14521
PathwayREACTOME_HATS_ACETYLATE_HISTONES

KAT7 ELP1 KAT6B CREBBP EP300

3.13e-04142595M27233
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

3.57e-047592MM1573
PathwayKEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_E3_UBIQUITIN_LIGASE_MALIN

PIK3R4 EPM2A

3.57e-047592M47977
PathwayWP_TYPE_2_PAPILLARY_RENAL_CELL_CARCINOMA

ARNT CREBBP EP300

3.80e-0434593M39771
PathwayKEGG_BUTANOATE_METABOLISM

PDHB AACS ACSM2A

3.80e-0434593M3397
PathwayPID_HIF2PATHWAY

ARNT CREBBP EP300

3.80e-0434593M44
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

4.74e-048592M22058
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

4.74e-048592M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

4.74e-048592M48024
PathwayKEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COAGULATION_CASCADE_PROTHROMBIN_TO_THROMBIN

F2 FCN3

4.74e-048592M47784
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

4.74e-048592M46443
PathwayWP_ANDROGEN_RECEPTOR_SIGNALING

KAT7 CREBBP EP300 SMAD3

5.64e-0491594M39700
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

6.08e-049592M47451
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

CREBBP EP300

7.58e-0410592M27945
PathwayREACTOME_SIGNALING_BY_SCF_KIT

SH2B3 VAV1 GRAP

7.63e-0443593M508
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

9.24e-0411592MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

9.24e-0411592M48021
PathwayPID_HES_HEY_PATHWAY

ARNT CREBBP EP300

1.05e-0348593M288
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

1.11e-0312592M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

1.11e-0312592M27765
PathwayREACTOME_P2Y_RECEPTORS

P2RY6 P2RY11

1.11e-0312592M10960
PathwayREACTOME_SIGNALING_BY_NOTCH3

NEURL1 CREBBP EP300

1.12e-0349593M618
PathwayPID_KIT_PATHWAY

SH2B3 CREBBP VAV1

1.33e-0352593M231
PathwayPID_NFAT_3PATHWAY

CABIN1 CREBBP EP300

1.41e-0353593M113
PathwayPID_AR_TF_PATHWAY

KAT7 CREBBP EP300

1.41e-0353593M151
PathwayWP_TGFBETA_SIGNALING_PATHWAY

CREBBP EP300 SMAD3

1.41e-0353593MM15880
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

ARNT TRIB3 CREBBP EP300

1.49e-03118594M27316
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

CREBBP EP300

1.52e-0314592M27808
PathwayWP_TGFBETA_RECEPTOR_SIGNALING

CREBBP EP300 SMAD3

1.57e-0355593M39351
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

PIK3R4 TRIB3 SH2B3 GRAPL EP300 VAV1 GRAP

1.73e-03418597MM15587
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

1.75e-0315592MM1339
PathwayBIOCARTA_HIF_PATHWAY

ARNT EP300

1.75e-0315592M13324
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

1.75e-0315592M10183
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

1.75e-0315592MM1439
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

CREBBP EP300

1.75e-0315592M953
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

NEURL1 CREBBP EP300

1.82e-0358593M29616
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

CREBBP EP300 SMAD3

1.92e-0359593M39886
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

CREBBP EP300

1.99e-0316592M27121
PathwayBIOCARTA_MEF2D_PATHWAY

CABIN1 EP300

1.99e-0316592MM1483
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

1.99e-0316592M1296
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

1.99e-0316592MM1420
PathwayREACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS

P2RY6 P2RY11

1.99e-0316592M6786
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

1.99e-0316592M8516
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES

CREBBP EP300

1.99e-0316592M27940
PathwayREACTOME_SARS_COV_1_TARGETS_HOST_INTRACELLULAR_SIGNALLING_AND_REGULATORY_PATHWAYS

EP300 SMAD3

1.99e-0316592M46428
PathwayREACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA

CREBBP EP300

2.25e-0317592M48025
PathwayBIOCARTA_MEF2D_PATHWAY

CABIN1 EP300

2.52e-0318592M5290
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

CREBBP EP300

2.52e-0318592M26942
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION

CREBBP EP300 SMAD3

2.64e-0366593M27938
PathwayREACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES

CREBBP EP300

2.81e-0319592M46442
PathwayWP_UROTENSINIIMEDIATED_SIGNALING

CREBBP EP300 SMAD3

3.00e-0369593M48052
PathwayWP_CALCIUM_MEDIATED_TCELL_APOPTOSIS_INVOLVED_IN_INCLUSION_BODY_MYOSITIS

CABIN1 EP300

3.12e-0320592M48330
PathwayKEGG_RENAL_CELL_CARCINOMA

ARNT CREBBP EP300

3.12e-0370593M13266
PathwayWP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX

CREBBP EP300

3.44e-0321592M39593
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

CREBBP EP300

3.44e-0321592M27485
PathwayKEGG_ADHERENS_JUNCTION

CREBBP EP300 SMAD3

3.52e-0373593M638
PathwayREACTOME_SIGNALING_BY_NOTCH1

NEURL1 CREBBP EP300

3.66e-0374593M616
PathwayBIOCARTA_VDR_PATHWAY

CREBBP EP300

3.77e-0322592MM1370
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION

EP300 SMAD3

3.77e-0322592MM15656
PathwayREACTOME_NPAS4_REGULATES_EXPRESSION_OF_TARGET_GENES

ARNT CREBBP

3.77e-0322592M46437
PathwayREACTOME_CELLULAR_RESPONSE_TO_HYPOXIA

ARNT CREBBP EP300

3.80e-0375593M641
Pubmed

Antigen presentation by CD1 and MHC-encoded class I-like molecules.

CD1A CD1B CD1D

5.43e-0848438729450
Pubmed

Lipid presentation by human CD1 molecules and the diverse T cell populations that respond to them.

CD1A CD1B CD1D

5.43e-08484324556395
Pubmed

CD1-dependent dendritic cell instruction.

CD1A CD1B CD1D

5.43e-08484312415264
Pubmed

Smad3 induces chondrogenesis through the activation of SOX9 via CREB-binding protein/p300 recruitment.

CREBBP EP300 SMAD3

1.35e-07584315623506
Pubmed

Isolation of CD1 genes: a family of major histocompatibility complex-related differentiation antigens.

CD1A CD1B CD1D

1.35e-0758433097645
Pubmed

TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300.

CREBBP EP300 SMAD3

1.35e-0758439679056
Pubmed

Polymorphism of human CD1 genes.

CD1A CD1B CD1D

1.35e-07584310488738
Pubmed

Dynamics of the antigen-binding grooves in CD1 proteins: reversible hydrophobic collapse in the lipid-free state.

CD1A CD1B CD1D

1.35e-07584323677998
Pubmed

CD1: antigen presentation and T cell function.

CD1A CD1B CD1D

1.35e-07584315032598
Pubmed

E1A inhibits transforming growth factor-beta signaling through binding to Smad proteins.

CREBBP EP300 SMAD3

1.35e-07584310497242
Pubmed

Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replication.

KAT7 KAT6B EP300

1.35e-07584317182677
Pubmed

IgG regulates the CD1 expression profile and lipid antigen-presenting function in human dendritic cells via FcgammaRIIa.

CD1A CD1B CD1D

1.35e-07584318337560
Pubmed

Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins.

CREBBP EP300 SMAD3

1.35e-07584312743039
Pubmed

A physical map linking the five CD1 human thymocyte differentiation antigen genes.

CD1A CD1B CD1D

1.35e-0758432583117
Pubmed

CD1 genotyping of patients with Mycobacterium malmoense pulmonary disease.

CD1A CD1B CD1D

1.35e-07584311580851
Pubmed

Role of CBP in regulating HIF-1-mediated activation of transcription.

ARNT CREBBP EP300

2.70e-07684315615775
Pubmed

Pokemon (FBI-1) interacts with Smad4 to repress TGF-β-induced transcriptional responses.

CREBBP EP300 SMAD3

4.72e-07784325514493
Pubmed

Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3).

CREBBP EP300 SMAD3

7.54e-07884314691252
Pubmed

Acetylation of HIV-1 integrase by p300 regulates viral integration.

KAT7 KAT6B EP300

2.21e-061184316096645
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

5.76e-06284227881875
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

5.76e-06284234845315
Pubmed

Myristoylation as a target for inhibiting HIV assembly: unsaturated fatty acids block viral budding.

NMT2 NMT1

5.76e-06284212244217
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

5.76e-06284219729597
Pubmed

CD1d-dependent macrophage-mediated clearance of Pseudomonas aeruginosa from lung.

RAG2 CD1D

5.76e-06284212042809
Pubmed

Thymus-Derived CD4+CD8+ Cells Reside in Mediastinal Adipose Tissue and the Aortic Arch.

RAG2 CD1D

5.76e-06284234740961
Pubmed

Quantitative mass spectrometry of diabetic kidney tubules identifies GRAP as a novel regulator of TGF-beta signaling.

GRAPL GRAP

5.76e-06284219836472
Pubmed

Dynamic changes in chromatin acetylation and the expression of histone acetyltransferases and histone deacetylases regulate the SM22alpha transcription in response to Smad3-mediated TGFbeta1 signaling.

EP300 SMAD3

5.76e-06284216876108
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

5.76e-06284239287984
Pubmed

Anatomy of CD1-lipid antigen complexes.

CD1A CD1B

5.76e-06284215864273
Pubmed

Human immunodeficiency virus type 1 protease triggers a myristoyl switch that modulates membrane binding of Pr55(gag) and p17MA.

NMT2 NMT1

5.76e-0628429971769
Pubmed

Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction.

GRAPL GRAP

5.76e-06284211971956
Pubmed

Antimyristoylation of the gag proteins in the human immunodeficiency virus-infected cells with N-myristoyl glycinal diethylacetal resulted in inhibition of virus production.

NMT2 NMT1

5.76e-0628422692561
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

5.76e-06284220717166
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

5.76e-06284225893291
Pubmed

Chemical characterization of p17gag from human immunodeficiency virus as an N-terminally myristoylated protein.

NMT2 NMT1

5.76e-0628422737204
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

5.76e-06284211559821
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

5.76e-06284232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

5.76e-06284219822209
Pubmed

Quantitative fluorescence resonance energy transfer microscopy analysis of the human immunodeficiency virus type 1 Gag-Gag interaction: relative contributions of the CA and NC domains and membrane binding.

NMT2 NMT1

5.76e-06284219403686
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

5.76e-06284224522976
Pubmed

Automated fluorescence lifetime imaging plate reader and its application to Förster resonant energy transfer readout of Gag protein aggregation.

NMT2 NMT1

5.76e-06284223184449
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

5.76e-06284221847097
Pubmed

Entropic switch regulates myristate exposure in the HIV-1 matrix protein.

NMT2 NMT1

5.76e-06284214699046
Pubmed

Global profiling of co- and post-translationally N-myristoylated proteomes in human cells.

NMT2 NMT1

5.76e-06284225255805
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

5.76e-06284234813504
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

5.76e-06284220301699
Pubmed

Immunosuppression and Aberrant T Cell Development in the Absence of N-Myristoylation.

NMT2 NMT1

5.76e-06284226423150
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

5.76e-06284224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

5.76e-06284237816914
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

5.76e-06284211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

5.76e-06284210918613
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

5.76e-06284235502657
Pubmed

Nef protein of human immunodeficiency virus type 1 binds its own myristoylated N-terminus.

NMT2 NMT1

5.76e-06284217261081
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

5.76e-06284231898871
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

5.76e-06284230888860
Pubmed

Myristoylation of gag proteins of HIV-1 plays an important role in virus assembly.

NMT2 NMT1

5.76e-0628422194551
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

5.76e-06284227881443
Pubmed

Opposing effects of human immunodeficiency virus type 1 matrix mutations support a myristyl switch model of gag membrane targeting.

NMT2 NMT1

5.76e-06284210074105
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

5.76e-06284219272189
Pubmed

Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein.

NMT2 NMT1

5.76e-06284210339411
Pubmed

Membrane binding of human immunodeficiency virus type 1 matrix protein in vivo supports a conformational myristyl switch mechanism.

NMT2 NMT1

5.76e-0628429261380
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

5.76e-06284232690000
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

5.76e-06284230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

5.76e-06284221803292
Pubmed

Differential membrane binding of the human immunodeficiency virus type 1 matrix protein.

NMT2 NMT1

5.76e-0628428970978
Pubmed

N-myristoyltransferase 1 is essential in early mouse development.

NMT2 NMT1

5.76e-06284215753093
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

5.76e-0628429811832
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

5.76e-06284224089570
Pubmed

Bacterial infection of Smad3/Rag2 double-null mice with transforming growth factor-beta dysregulation as a model for studying inflammation-associated colon cancer.

RAG2 SMAD3

5.76e-06284219119184
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

5.76e-06284215706485
Pubmed

Binding of human immunodeficiency virus type 1 Gag to membrane: role of the matrix amino terminus.

NMT2 NMT1

5.76e-06284210196310
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

5.76e-06284239266679
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

5.76e-06284222303793
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

5.76e-06284234732714
Pubmed

An SH2 domain-dependent, phosphotyrosine-independent interaction between Vav1 and the Mer receptor tyrosine kinase: a mechanism for localizing guanine nucleotide-exchange factor action.

MERTK VAV1

5.76e-06284212920122
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

5.76e-06284234019788
Pubmed

Detection of Grb-2-related adaptor protein gene (GRAP) and peptide molecule in salivary glands of MRL/lpr mice and patients with Sjögren's syndrome.

GRAPL GRAP

5.76e-06284215174222
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

5.76e-06284215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

5.76e-06284229460469
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

5.76e-06284224551300
Pubmed

Myristoylation-dependent replication and assembly of human immunodeficiency virus 1.

NMT2 NMT1

5.76e-0628422405382
Pubmed

Matrix-induced inhibition of membrane binding contributes to human immunodeficiency virus type 1 particle assembly defects in murine cells.

NMT2 NMT1

5.76e-06284216306631
Pubmed

The biology and enzymology of protein N-myristoylation.

NMT2 NMT1

5.76e-06284211527981
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

5.76e-06284233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

5.76e-0628429018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

5.76e-06284224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

5.76e-06284230135524
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

5.76e-06284216596650
Pubmed

CSMD1 exhibits antitumor activity in A375 melanoma cells through activation of the Smad pathway.

CSMD1 SMAD3

5.76e-06284222538441
Pubmed

The effect of HIV-1 Gag myristoylation on membrane binding.

NMT2 NMT1

5.76e-06284216183191
Pubmed

A second mammalian N-myristoyltransferase.

NMT2 NMT1

5.76e-0628429506952
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

5.76e-06284229217654
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

5.76e-06284210049825
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

5.76e-06284227380996
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

5.76e-06284229170789
Pubmed

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

CREBBP EP300

5.76e-06284221555743
Pubmed

CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.

CREBBP EP300

5.76e-06284212646247
Pubmed

Efficient particle formation can occur if the matrix domain of human immunodeficiency virus type 1 Gag is substituted by a myristylation signal.

NMT2 NMT1

5.76e-0628427521919
Pubmed

Blockage of N-myristoylation of HIV-1 gag induces the production of impotent progeny virus.

NMT2 NMT1

5.76e-0628429299393
Pubmed

Grb2-related adaptor protein GRAP is a novel regulator of liver fibrosis.

GRAPL GRAP

5.76e-06284237343720
InteractionNR6A1 interactions

ARNT EFNA4 CREBBP EP300

2.54e-0624824int:NR6A1
InteractionDPM1 interactions

ARNT P2RY6 TNIP1 MERTK PRPF8 RHOF EP300

6.73e-06173827int:DPM1
InteractionPRKDC interactions

ARNT EFNA4 MEX3A P2RY6 ELP1 ATG4C TNIP1 MERTK PRPF8 RHOF EP300 SMAD3

2.34e-056958212int:PRKDC
InteractionCIMAP1D interactions

NMT2 NMT1 TRAPPC9

2.85e-0515823int:CIMAP1D
InteractionKAT6A interactions

KAT7 MEX3A AP3B2 PHF14 KAT6B PRPF8 CREBBP EP300 TOE1 SMAD3

4.13e-055108210int:KAT6A
InteractionSAXO1 interactions

TNK1 TRIB3 FAM124A MVP

5.08e-0550824int:SAXO1
Cytoband1q22-q23

CD1A CD1B CD1D

1.67e-06138431q22-q23
Cytoband3q25.32

RARRES1 IQCJ

1.80e-04118423q25.32
Cytoband9q33.2

TTLL11 PAPPA

2.35e-03398429q33.2
Cytoband10p13

FRMD4A NMT2

2.85e-034384210p13
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

KAT7 KAT6B CREBBP EP300

1.64e-0717544486
GeneFamilySH2 domain containing

SH2B3 GRAPL VAV1 GRAP

2.34e-04101544741
GeneFamilyC1-set domain containing

CD1A CD1B CD1D

2.66e-0442543591
GeneFamilyPurinergic receptors P2Y

P2RY6 P2RY11

3.88e-0410542213
GeneFamilyZinc fingers C2HC-type|PHD finger proteins|Lysine acetyltransferases

KAT7 KAT6B

1.02e-031654266
GeneFamilyAtypical dual specificity phosphatases

EPM2A DUSP15

1.30e-0318542896
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.30e-031854291
GeneFamilyAcyl-CoA synthetase family

AACS ACSM2A

2.72e-032654240
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Calb2_(MGE-derived_cortical_interneurons--Martinotti_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TMEM267 IQCJ PAPPA MAMDC4

1.06e-05738348e8d06bd4404fe6fda753e7adedc2f2150524750
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Calb2_(MGE-derived_cortical_interneurons--Martinotti_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TMEM267 IQCJ PAPPA MAMDC4

1.06e-057383448a499fa03d736310d09b01c8889db5288e9b2da
ToppCelldroplet-Limb_Muscle-nan-3m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL5 BIVM NEURL4 RHOF VAV1

1.48e-0516683535db3022c33d6f8bb6587d9eec89a7cccb70271a
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 RARRES1 ADAMTSL5 SACS MYOM2

1.76e-05172835073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCellDendritic_Cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

CD1A CD1B CD1D P2RY6 CDCP2

1.91e-05175835584290a51f9975782a5ac8c6ad67c778d8323f8c
ToppCelldroplet-Heart-nan-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEX3A PAPPA DUSP15 CSMD1 NEURL4

2.76e-051898350493f7b79127c207fd7ade778ef4810500495d7e
ToppCell(3)_MNP-(3)_DC_2|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

CD1A CD1B CD1D P2RY6 RHOF

2.90e-051918353ff163484af8c12ef4eef87246cf044257fd2547
ToppCellCOVID-19-Myeloid-DC2|Myeloid / Condition, Lineage and Cell class

CD1A CD1B CD1D P2RY6 RHOF

3.05e-051938355f3f6db3d3de887d004662d229f42549601efa81
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD1A CD1B P2RY6 CH25H RHOF

3.13e-05194835e56c6e5c9b7d287ae94566b561e21cec2055f83d
ToppCelldistal-Hematologic-Myeloid_Dendritic_Type_2-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD1A CD1B CD1D SACS P2RY6

3.21e-051958357606b8b40e704bb5447ac57ccf8698794e9c7890
ToppCell356C-Myeloid-Dendritic-cDC2|356C / Donor, Lineage, Cell class and subclass (all cells)

CD1A CD1B CD1D P2RY6 CH25H

3.21e-051958354c9a2167d8cfe40dfd609c303ada5b5ef800bd8f
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CD1A CD1B P2RY6 CH25H RHOF

3.21e-0519583585fee07d71c0393ea42bcf1130566dff4a62f507
ToppCellLeuk-UTI-Myeloid-cDC2|Leuk-UTI / Disease, Lineage and Cell Type

CD1B CD1D P2RY6 PDHB ATG4C

3.29e-0519683550465a082f03201936733c55af73bc32e1bdd024
ToppCellControl-Myeloid-DC2|Control / Condition, Lineage and Cell class

CD1A CD1B P2RY6 CH25H RHOF

3.29e-051968350ccc26c2811e4c8631e0abd8555b167ac1e7a982
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Dendritic_cells|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

CD1A CD1B CD1D P2RY6 RHOF

3.29e-05196835f278b144b8deaee0bf41682081b9fbb0b1e82b19
ToppCellControl-Myeloid-DC2|Myeloid / Condition, Lineage and Cell class

CD1A CD1B P2RY6 CH25H RHOF

3.37e-05197835e0ee15188ff0d9df3c3b5ea523553ce18d223c33
ToppCellproximal-3-Hematologic-Myeloid_Dendritic_Type_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD1A CD1B CD1D SH2B3 P2RY6

3.45e-051988352e07e62ed230763a6859a8ce19429b5ca8b365a6
ToppCellproximal-Hematologic-Myeloid_Dendritic_Type_2|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD1A CD1B CD1D SH2B3 P2RY6

3.45e-051988353b0143efc33486c1e340ca57981c83cf7e2cad29
ToppCellTracheal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CD1A SH2B3 P2RY6 MERTK ARAP1

3.45e-051988350b928a829844f49f4d47e88908af192cb919011f
ToppCellproximal-Hematologic-Myeloid_Dendritic_Type_2-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD1A CD1B CD1D SH2B3 P2RY6

3.45e-05198835f254287e13328a8f3b14bf4e44736041ad35593e
ToppCellnormal_Lung-Myeloid_cells-CD1c+_DCs|normal_Lung / Location, Cell class and cell subclass

CD1A CD1B CD1D SH2B3 P2RY6

3.45e-0519883585d9bf50a1a5adaab52bab88317acd870d1704d6
ToppCelltumor_Lung-Myeloid_cells-CD1c+_DCs|tumor_Lung / Location, Cell class and cell subclass

CD1A CD1B CD1D SH2B3 P2RY6

3.53e-05199835de65f2f41a507ae98d27c37aedac7fdbf2d3c697
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CD1D SH2B3 P2RY6 MERTK VAV1

3.53e-051998356ce7612ee2ae211eb0f73391e96089ad5431c537
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FRMD4A SH2B3 NEURL4 TOE1 RAVER1

3.62e-0520083588d713dfc792e7609bf7ecfb28f87cb748088570
ToppCellTransverse-Dendritic_cell|Transverse / Region, Cell class and subclass

CD1A CD1B CD1D SH2B3 P2RY6

3.62e-05200835b0e9eaf0e57e53645e272e2cea9f09bfcfe12a9b
ToppCellTransverse-(5)_Dendritic_cell|Transverse / shred on region, Cell_type, and subtype

CD1A CD1B CD1D SH2B3 P2RY6

3.62e-052008356c32a64f7c38818b93eec1e2d41067e5dbd90541
ToppCellSepsis-Leuk-UTI-Myeloid-cDC2|Leuk-UTI / Disease, condition lineage and cell class

CD1B CD1D P2RY6 PDHB ATG4C

3.62e-052008351f1611c590230cd50b9bdca6b58291ab3aab85f2
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial|GW12 / Sample Type, Dataset, Time_group, and Cell type.

PLA2R1 EFNA4 P2RY6 P2RY11 MERTK

3.62e-05200835be1abe5bb1ce4e7dfec63af4ed0fc5b96bf77866
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FOXRED1 SACS P2RY6 TTLL11

1.36e-04140834276b3fa924176426efb31112ed4d355407f0b218
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD1B CD1D SH2B3 P2RY6

2.12e-04157834e9d0300361b06aec3c216f8af15f09e14b12a4da
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPM2A NEURL1 CSMD1 F2

2.12e-041578341f21d78a467fe22c5ab75d0917b840c1ac93f32c
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CD1B CD1D SH2B3 P2RY6

2.17e-04158834e9657d8960d499832f9f9b45b5a6f4388551b7e1
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-5|TCGA-Stomach / Sample_Type by Project: Shred V9

MEX3A PROCA1 DUSP15 F2

2.22e-04159834c40fe552da3abdb1df87e9e1647468dc038bec0a
ToppCellnormal_Lung-Myeloid_cells-Pleural_Mac|normal_Lung / Location, Cell class and cell subclass

CD1A CD1B CD1D P2RY6

2.22e-04159834f95a5570bf153fc5c598aba855db6b47ba818463
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-T_entry|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RAG2 CD1A CD1B LCT

2.39e-04162834a27750117e7f16a0bd07cc5f58a56becb39e800b
ToppCelltumor_Lung-Myeloid_cells-Pleural_Mac|tumor_Lung / Location, Cell class and cell subclass

CD1A CD1B CD1D P2RY6

2.39e-041628349ac3242511315224ed94582aca9e9a3786cd01a0
ToppCellPBMC-Severe-Myeloid-cDC-cDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CD1B CD1D EPM2A CH25H

2.44e-04163834ec8336b68c8369e27d507c04c827be07bb48a7f6
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-cDC2|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD1A CD1B CD1D SACS

2.68e-041678341bd0aa7a3c8649f342bb856cf861c4c5984ad889
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-neuroepithelial-like_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

PIK3R4 PLA2R1 TRIB3 MYOM2

2.68e-04167834e488d9c7cf4355959e3833de3bd496c13fc11b1b
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

EML5 P2RY11 ZFYVE26 DENND4C

2.68e-04167834a48349f189f6a8d563744b0a294c3974f3a18f50
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 ADAMTSL5 MYOM2 MERTK

2.80e-0416983487116c33c5ca8cb1862e103e5607b1df4d264569
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD1B CD1D SH2B3 P2RY6

2.87e-041708347bba77ae34a0259fad6ee98cf665ff50f77a1328
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CD1B CD1D SH2B3 P2RY6

2.87e-04170834a43b977a7fe745536cf96b7c080397d9fa73086b
ToppCellTCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma-Usual_Type-4|TCGA-Adrenal / Sample_Type by Project: Shred V9

EFNA4 AACS IDH1 RHOF

3.13e-0417483415e2b9f46404ff9575e149024b24cb17b50b02b5
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG2 EFNA4 ACR TTLL11

3.27e-041768343766e0533b103ec92ac75eba3df02e287efc53fa
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG2 EFNA4 ACR TTLL11

3.27e-04176834aa1bada2175d8370fc71939a607407155259d195
ToppCell10x3'2.3-week_17-19-Myeloid_DC-DC-DC3|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CD1A CD1B CD1D P2RY6

3.27e-041768347762e5d7c11756da605a604a289216bb53e25869
ToppCellNS-moderate-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

STARD4 SH2B3 P2RY6 RHOF

3.34e-04177834de1ffe3df76100d46ca158bdd2fea2ebbd4656b4
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

FRMD4A INTU P2RY6 MERTK

3.56e-041808347be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG2 TTLL11 DUSP15 MYOM2

3.63e-04181834145fae2746c5212640b7b11b04a7759ba8e5c322
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG2 TTLL11 DUSP15 MYOM2

3.63e-04181834a9f1fc5973cffdbeb7d1f5c41534422d85d596ff
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TTLL11 MYOM2 KAT6B TRAPPC9

3.71e-04182834c6172aca2475bf0948a78e39f0dae6388504a915
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRMD4A CD1B P2RY6 MERTK

3.71e-04182834ea39b1b5db185b0cb11dfa2e01f3f972effbd770
ToppCell10x5'v1-week_17-19-Myeloid_DC-DC-tDC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EML5 P2RY6 MVP RHOF

3.71e-04182834ad5c99ec62cdab347d3a03c971d981e3b924020c
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD1c+_DCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

CD1A CD1B CD1D SH2B3

3.71e-04182834551d301adfb4d5046c5f60f6996450621b04e9b2
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL5 PAPPA FAM124A LCT

3.79e-04183834ebe369dc80c4fbf8f4dbe947147f8c47507ffb60
ToppCellmild-Myeloid-mDC|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CD1B CD1D SH2B3 P2RY6

3.87e-041848348b37c00d59d9992d3b43268991da7bb94646c70e
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-CD163+CD14+_DCs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

CD1A CD1B SH2B3 P2RY6

3.87e-041848342dc4b2a9970111ed5e2977fc178595a12d7bb59d
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 RARRES1 ADAMTSL5 MYOM2

3.87e-041848341c857126c0ea0671f0d60b048efca288d348d653
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D175|Adult / Lineage, Cell type, age group and donor

FRMD4A P2RY6 MERTK VAV1

3.95e-04185834ab5704b96f1d368911308797d10c7c52766ab134
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRMD4A P2RY6 ATG4C MERTK

3.95e-041858348207f9eff113eed429e961748c6b17d672a13b33
ToppCell10x5'-GI_small-bowel-Myeloid_Dendritic-DC2|GI_small-bowel / Manually curated celltypes from each tissue

CD1A CD1B CD1D P2RY6

3.95e-04185834f78be85dd6e443abb7af20f98ff351c1131ece4d
ToppCell(0)_MSCs|World / Cell class and subclass of bone marrow stroma cells in homeostatis

CD1D PAPPA CSMD1 IGSF3

4.03e-04186834a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell(0)_MSCs-(00)_Lepr-MSC|World / Cell class and subclass of bone marrow stroma cells in homeostatis

CD1D PAPPA CSMD1 IGSF3

4.03e-04186834f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCellCOVID_non-vent-Myeloid-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

CD1B CD1D SH2B3 P2RY6

4.11e-04187834936aaca144b79a809617cbe3058bf434a4b3d46a
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SH2B3 P2RY6 ATG4C MERTK

4.11e-0418783439b99f46b723f7f3c44880d7fe8642cbad558b8a
ToppCellCOVID_non-vent-Myeloid-Dendritic-cDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

CD1B CD1D SH2B3 P2RY6

4.11e-0418783455fe4e8b4f301876716c1af15c34d42164f2358e
ToppCell3'_v3-Lung-Myeloid_Dendritic-DC2|Lung / Manually curated celltypes from each tissue

CD1A CD1B CD1D P2RY6

4.36e-04190834468525c05e38158a3b8a445882b2d63dfb1d2c63
ToppCellCOVID-19-Myeloid-DC2|COVID-19 / Condition, Lineage and Cell class

CD1A CD1B CD1D P2RY6

4.45e-041918341304ab7b5713f29f3966ffc020ea1b52e8e2f375
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

FRMD4A CD1D PAPPA IGSF3

4.45e-0419183478ad7c555409ce1391bce406bc0f3ef575329ece
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CD1B CD1D SH2B3 P2RY6

4.45e-0419183492c5a26b90a55831039220341d863cf2940f3c9b
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD1B CD1D SH2B3 P2RY6

4.54e-041928346184163dbfca882824cb266bb9030d9f79e3acb0
ToppCell367C-Myeloid-Dendritic|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CD1A CD1B P2RY6 RHOF

4.54e-04192834877aaf61d8fc40e7013944a0180306dd0bb0557f
ToppCell367C-Myeloid-Dendritic-cDC2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CD1A CD1B CD1D RHOF

4.63e-04193834940e9a419d0de1f9e72b5cc9c86684057003be58
ToppCellMNPs-Dendritic_Cells|MNPs / lung cells shred on cell class, cell subclass, sample id

CD1A CD1B CD1D P2RY6

4.63e-041938340e6b8e179bfe1c6e93137c76c76a91c7782a4989
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)|Adult / Lineage, Cell type, age group and donor

FRMD4A SH2B3 P2RY6 MERTK

4.63e-0419383431c0978ba78c9516d498aec0798902e57555e557
ToppCellwk_15-18-Hematologic-Myeloid-Cycling_DC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CD1A CD1B CD1D P2RY6

4.63e-041938348e6d31546f7150ab3e8ad4fde075839e6c33842a
ToppCellImmune-interstitial_macrophage_(C1Q_positive)|World / Lineage, Cell type, age group and donor

FRMD4A SH2B3 P2RY6 MERTK

4.63e-0419383464d598162a256ac6c9f8280c8a9133661dfbb10f
ToppCell367C-Myeloid-Dendritic|367C / Donor, Lineage, Cell class and subclass (all cells)

CD1A CD1B CD1D P2RY6

4.63e-04193834365e831ae6ac67fb36d8d70ef139f4ae7e32c83f
ToppCellLAM-Myeloid-DC|Myeloid / Condition, Lineage and Cell class

CD1A CD1B P2RY6 MERTK

4.63e-04193834f665cce40053ae5d6e28f9f70ddf78e8598c9514
ToppCellcontrol-Myeloid-mDC|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CD1B CD1D SH2B3 P2RY6

4.63e-041938345e43024763932a679c33d83cf8f606612bc0f600
ToppCell10x5'-Lung-Myeloid_Dendritic-DC2|Lung / Manually curated celltypes from each tissue

CD1A CD1B CD1D P2RY6

4.63e-04193834c97f9b13057f803df63c696c6175ef8e0aba6fa7
ToppCellDendritic_Cells|World / lung cells shred on cell class, cell subclass, sample id

CD1A CD1B CD1D P2RY6

4.63e-041938347792eb6e247af2d7a8f80476f37dcd880922d625
ToppCell10x5'v1-week_14-16-Myeloid_DC-DC-DC2|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CD1A CD1B CD1D P2RY6

4.72e-04194834a0cfc8c1cdc0722db39170e4417615b6e6b85041
ToppCellcellseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CD1A CD1B CD1D P2RY6

4.72e-04194834024568d8a862f0fe4da1f66a58c6e71f0e8279f3
ToppCell343B-Myeloid-Dendritic-cDC2|343B / Donor, Lineage, Cell class and subclass (all cells)

CD1A CD1B CD1D P2RY6

4.72e-04194834aa6c9b71006fd3863a802d112d9c3838865a52bf
ToppCellControl-Myeloid-MoAM4|Myeloid / Condition, Lineage and Cell class

CD1A CD1B P2RY6 CH25H

4.72e-041948347ab808dd1876b0eec2831caa16d04fd859b1dc50
ToppCelldistal-2-Hematologic-Myeloid_Dendritic_Type_2|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD1A CD1B CD1D SACS

4.72e-041948346881cfe12837a32e598535a564e4c31d4846167b
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CD1A CD1B P2RY6 CSMD1

4.72e-04194834bde6830a281f7cd7fd1733e40a41ddd2673ba88e
ToppCellcellseq-Immune-Immune_Myeloid-Myeloid_Dendritic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CD1A CD1B CD1D P2RY6

4.72e-0419483474d588de2f84a4ef112fd642f7e112a542d5ef11
ToppCellBronchial_Brush-Immune-Dendritic_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

CD1D SH2B3 P2RY6 RHOF

4.72e-04194834dbcc00940538efc0f89f074dbe822c50efa5ad8e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRMD4A SH2B3 MERTK VAV1

4.72e-04194834c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD1A CD1D SH2B3 P2RY6

4.72e-0419483459180fe75be386530f1be668a37e4ada2eb19ddc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FRMD4A SH2B3 MERTK DENND4C

4.72e-0419483445708cb2cafde10bf4e4798b81d47c3b1f6aaa14
ToppCell367C-Myeloid-Dendritic-cDC2|367C / Donor, Lineage, Cell class and subclass (all cells)

CD1A CD1B CD1D P2RY6

4.72e-04194834d0ffba657c7308feecaa62dd54c920d32be0f129
ToppCell343B-Myeloid-Dendritic-cDC2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CD1A CD1B P2RY6 RHOF

4.72e-04194834ccb04f0788c98e0f63f18b09484d75ac536412a1
ToppCell356C-Myeloid-Dendritic|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CD1A CD1B P2RY6 RHOF

4.81e-04195834ba8b8831bd5f544f4e25f13949d04e164ecdcd12
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD1A CD1B CD1D P2RY6

4.81e-041958349cfbdb528088ad0ab100c7431c7d8f140a846de8
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CD1A CD1B CD1D P2RY6

4.81e-041958347bb3bdfb8caaae357b1f7841d8d00936c4373dfe
ToppCellMonocytes-M2-like_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

FRMD4A P2RY6 CH25H MERTK

4.81e-0419583410fa47bdcf6c9784ea930b75a5861e139421feed
DrugCoA group

KAT7 PDHB NMT2 AACS IDH1 KAT6B NMT1 ACSM2A CREBBP EP300 PCSK9

4.32e-074338211CID000000317
Drug3,4-dimethoxy-N-((2,2-dimethyl-2H-chromen-6-yl)methyl)-N-phenylbenzenesulfonamide

ARNT CREBBP EP300

4.48e-075823ctd:C575894
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

FRMD4A TRIB3 P2RY6 KAT6B EP300 TOE1 SMAD3

2.51e-061688273868_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

EPM2A TRIB3 P2RY6 KAT6B CREBBP TOE1 SMAD3

2.51e-061688273395_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

TRIB3 P2RY6 KAT6B CREBBP EP300 TOE1 SMAD3

2.82e-061718276879_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

ARNT TRIB3 KAT6B NMT1 EP300 TOE1 SMAD3

3.17e-061748275745_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA

TRIB3 P2RY6 KAT6B CREBBP EP300 TOE1 SMAD3

3.29e-061758271014_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

TRIB3 P2RY6 KAT6B CREBBP EP300 TOE1 SMAD3

3.55e-061778273227_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

EPM2A TRIB3 KAT6B NMT1 CREBBP TOE1 SMAD3

3.55e-061778273177_DN
Drug2-propylpentanoic acid; Down 200; 500uM; HL60; HT_HG-U133A

EPM2A TNIP1 KAT6B NMT1 GMPPA VAV1 SMAD3

7.17e-061978271181_DN
Drug11-ethylthioundecanoic acid

NMT2 NMT1

1.28e-052822CID000122099
Drug3-methyl-2-pentanol

GRAPL GRAP

1.28e-052822CID000011261
DrugAC1L1G5B

KAT7 INTU KAT6B EP300

2.27e-0546824CID000003531
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

FRMD4A EPM2A TRIB3 P2RY6 KAT6B TOE1

2.84e-051648264388_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

TRIB3 P2RY6 KAT6B CREBBP TOE1 SMAD3

2.94e-051658262835_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

EPM2A TRIB3 P2RY6 KAT6B EP300 TOE1

2.94e-051658265625_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

TRIB3 KAT6B CREBBP EP300 TOE1 SMAD3

3.47e-051708261050_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

EPM2A TRIB3 KAT6B CREBBP EP300 TOE1

3.47e-051708263746_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

TRIB3 P2RY6 KAT6B CREBBP TOE1 SMAD3

3.71e-051728263428_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

TRIB3 KAT6B NMT1 CREBBP EP300 TOE1

3.71e-051728262794_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

FRMD4A EPM2A TRIB3 P2RY6 KAT6B SMAD3

3.71e-051728265903_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

EPM2A TRIB3 P2RY6 KAT6B CREBBP TOE1

3.83e-051738263243_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

TRIB3 P2RY6 KAT6B CREBBP TOE1 SMAD3

3.96e-051748263462_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

TRIB3 KAT6B NMT1 CREBBP EP300 SMAD3

3.96e-051748261659_DN
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA

TRIB3 KAT6B CREBBP EP300 TOE1 SMAD3

4.09e-051758261058_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

TRIB3 P2RY6 KAT6B CREBBP TOE1 SMAD3

4.22e-051768266784_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

TRIB3 P2RY6 KAT6B CREBBP TOE1 SMAD3

4.22e-051768261535_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

EPM2A TRIB3 P2RY6 KAT6B CREBBP SMAD3

4.22e-051768263312_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

TRIB3 P2RY6 KAT6B EP300 TOE1 SMAD3

4.35e-051778267550_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

TRIB3 P2RY6 KAT6B CREBBP TOE1 SMAD3

4.49e-05178826992_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

EPM2A TRIB3 P2RY6 KAT6B EP300 TOE1

4.49e-051788264710_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

TRIB3 KAT6B NMT1 CREBBP EP300 SMAD3

4.64e-051798265822_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

TRIB3 KAT6B CABIN1 CREBBP EP300 TOE1

4.64e-051798266609_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

TRIB3 P2RY6 KAT6B CREBBP EP300 SMAD3

4.78e-051808264821_DN
DrugAustricine [10180-88-8]; Up 200; 14.2uM; MCF7; HT_HG-U133A

CD1A ARNT PAPPA CABIN1 NMT1 TRAPPC9

7.89e-051978262812_UP
DrugPF-00539745-00 [351321-33-0]; Down 200; 10uM; PC3; HT_HG-U133A

EPM2A ARNT CABIN1 NMT1 SMAD3 EPHA5

7.89e-051978265939_DN
Drug0198306-0000 [212631-61-3]; Up 200; 10uM; MCF7; HT_HG-U133A

NEURL1 KAT6B NMT1 CREBBP ARAP1 SMAD3

8.11e-051988267064_UP
DrugAscorbic acid [50-81-7]; Down 200; 22.4uM; HL60; HG-U133A

AACS CABIN1 NMT1 TRAPPC9 TOE1 ARAP1

8.57e-052008261610_DN
Drugalpha-GalCer

RAG2 CD1A CD1B CD1D KAT6B

1.12e-04131825CID002826713
DrugNSC237521

RAG2 CD1A CD1B CD1D SH2B3 AP3B2

1.12e-04210826CID000428410
DrugRifater

MERTK RHOF

1.27e-045822CID006474062
Drugchloroquinone

INTU SH2B3

1.27e-045822CID000069671
DrugN-myristoylGly

NMT2 NMT1

1.27e-045822CID000072348
Druganacardic acid

KAT7 KAT6B EP300

1.70e-0430823CID000167551
DiseasePrecursor Cell Lymphoblastic Leukemia Lymphoma

ARNT SH2B3 IDH1 CREBBP EP300

7.25e-0761815C1961102
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

7.44e-062812180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

7.44e-062812cv:C4551859
DiseaseMenke-Hennekam syndrome

CREBBP EP300

7.44e-062812cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

7.44e-062812DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

7.44e-062812cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

7.44e-062812C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

7.44e-062812DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

7.44e-062812C0035934
DiseaseNon-alcoholic Fatty Liver Disease

RAG2 TRIB3 TM6SF2 F2

4.21e-0570814C0400966
DiseaseNonalcoholic Steatohepatitis

RAG2 TRIB3 TM6SF2 F2

4.21e-0570814C3241937
Diseasemuscular disease (implicated_via_orthology)

NMT2 NMT1

7.40e-055812DOID:0080000 (implicated_via_orthology)
DiseaseMyocardial Infarction

SH2B3 PAPPA TM6SF2 F2

1.39e-0495814C0027051
DiseaseAdenocarcinoma of lung (disorder)

TNK1 CREBBP EP300 VAV1 EPHA5

2.63e-04206815C0152013
DiseaseGlioma

ELP1 IDH1

2.65e-049812cv:C0017638
Diseaseglucagon-like peptide-1 measurement

CSMD1 AGBL1

3.30e-0410812EFO_0008465
DiseaseAcute Cerebrovascular Accidents

SH2B3 PRPF8 F2

4.47e-0454813C0751956
DiseaseHematologic Neoplasms

SH2B3 IDH1

4.83e-0412812C0376545
DiseaseThromboembolism

MERTK F2

4.83e-0412812C0040038
Diseaseserum non-albumin protein measurement

ARNT SH2B3 CH25H TNIP1 ARAP1 SMAD3

4.83e-04361816EFO_0004568
Diseaseneurofilament light chain measurement

CD1A CD1B CD1D

5.24e-0457813EFO_0009178
Diseaserostral middle frontal gyrus volume measurement

PLA2R1 AGBL1

6.63e-0414812EFO_0010328
DiseaseCerebrovascular accident

SH2B3 PRPF8 F2

6.71e-0462813C0038454
Diseasehemorrhoid

FRMD4A PAPPA MERTK SMAD3

7.31e-04147814EFO_0009552
Diseasemyelodysplastic syndrome (implicated_via_orthology)

PRPF8 CREBBP

7.64e-0415812DOID:0050908 (implicated_via_orthology)
DiseaseCoronary Arteriosclerosis

SH2B3 PAPPA PCSK9

7.70e-0465813C0010054
DiseaseCoronary Artery Disease

SH2B3 PAPPA PCSK9

7.70e-0465813C1956346
DiseaseFamilial Progressive Myoclonic Epilepsy

EPM2A SACS

9.85e-0417812C0751777
DiseaseAtypical Inclusion-Body Disease

EPM2A SACS

9.85e-0417812C0751776
DiseaseMyoclonic Epilepsies, Progressive

EPM2A SACS

9.85e-0417812C0751778
DiseaseBiotin-Responsive Encephalopathy

EPM2A SACS

9.85e-0417812C0751780
DiseaseMay-White Syndrome

EPM2A SACS

9.85e-0417812C0751782
DiseaseDentatorubral-Pallidoluysian Atrophy

EPM2A SACS

9.85e-0417812C0751781
DiseaseAction Myoclonus-Renal Failure Syndrome

EPM2A SACS

1.11e-0318812C0751779
Diseasediffuse plaque measurement

FRMD4A PLA2R1 TTLL11 CH25H TNIP1 FAM124A KAT6B ACSM2A

1.13e-03758818EFO_0010699
Diseaseglomerulonephritis (is_marker_for)

F2 EP300

1.23e-0319812DOID:2921 (is_marker_for)
Diseasehemifacial microsomia

FRMD4A NMT1

1.23e-0319812MONDO_0015398
Diseaseautoimmune disease

SH2B3 TNIP1 NEURL4 RAVER1

1.34e-03173814EFO_0005140
DiseaseLeukemia, Myelocytic, Acute

SH2B3 IDH1 CREBBP EP300

1.34e-03173814C0023467
Diseaseproprotein convertase subtilisin/kexin type 9 measurement

TM6SF2 PCSK9

1.66e-0322812EFO_0009312
DiseaseHMG CoA reductase inhibitor use measurement

TM6SF2 DENND4C SMAD3 PCSK9

1.85e-03189814EFO_0009932
Diseaseankylosing spondylitis

SH2B3 MYOM2 CSMD1

2.03e-0391813EFO_0003898
Diseasealpha-linolenic acid measurement

CSMD1 LCT

2.14e-0325812EFO_0007759
Diseaselevel of Sterol ester (27:1/16:0) in blood serum

TM6SF2 PCSK9

2.32e-0326812OBA_2045191
Diseasecholesterol to total lipids in small LDL percentage

TM6SF2 PCSK9

2.50e-0327812EFO_0022241
Diseaselumbar disc degeneration

CSMD1 SMAD3

2.69e-0328812EFO_0004994

Protein segments in the cluster

PeptideGeneStartEntry
RPLAQPACLTFWYHG

MAMDC4

881

Q6UXC1
VHCTGYIKAWPPAGV

ARNT

306

P27540
KKLGYTTGHIWACPP

EP300

1426

Q09472
DCIWLITVPPGHGVY

CSMD1

2171

Q96PZ7
PGIWAHGDYCRINPK

AACS

516

Q86V21
CARAKRPGIYTATWP

ACR

266

P10323
IRCHWTIRLPPGYQV

CDCP2

281

Q5VXM1
PWALGACTFVHLLPK

ACSM2A

276

Q08AH3
AVAHPSLIWRCGYSK

EPHA5

611

P54756
KPHPWYSGRISRQLA

GRAPL

56

Q8TC17
KPHPWYSGRISRQLA

GRAP

56

Q13588
KGDVSLCRWHPKPYC

FBXO34

641

Q9NWN3
VKKLGYVTGHIWACP

CREBBP

1461

Q92793
GHYPWSCPVTHTREK

BIVM

51

Q86UB2
QLVCHVSGFYPKPVW

CD1B

221

P29016
WYGPAVVAHILRKAV

ATG4C

231

Q96DT6
LGKPTWIRTGHEICY

AGBL1

676

Q96MI9
WLIGEYCEHVPRIAP

AP3B2

506

Q13367
WPKRSCPTGVFHLDV

RAG2

36

P55895
KPLGPRTLYVHWTDA

RAVER1

196

Q8IY67
APVGKIHPYISWRLQ

IQCJ

101

Q1A5X6
CGWFHPPANEIYRRK

KAT6B

771

Q8WYB5
WYHLCLPEGRALPVF

FCN3

106

O75636
YGHCPGLKVVSPWNS

PDHB

166

P11177
PPKHWRYGEAACRLE

P2RY11

91

Q96G91
HYSRILPNIWLGSCP

EPM2A

156

O95278
AKCVWKHPPGDEIYR

KAT7

386

O95251
VLPKPVGTCRYWHRS

NMT1

286

P30419
GVVLPKPIATCRYWH

NMT2

286

O60551
VKIFIPAHGWVDYAP

MERTK

476

Q12866
CALGRVPWRKFPVHV

AQP7B

106

A0A075B734
LVCHVSGFYPKPVWV

CD1A

221

P06126
GTPLWAIRPVHYGKE

FAM124A

156

Q86V42
RCAKDPWRLPGTYVV

PCSK9

66

Q8NBP7
PRAYKRWVCSLPFGH

EFNA4

91

P52798
PGWAPYRIAHAVIKA

LCT

1086

P09848
WDPVTPYRLHVLCQG

ELP1

351

O95163
RVVCTAGLKWYPHPA

PAPPA

1536

Q13219
GRWVHIVCALYVPGV

PHF14

401

O94880
SPLRAREYVWAPGHC

ADAMTSL5

411

Q6ZMM2
HWLIRGPLEYVPSAK

MVP

356

Q14764
AYWVVGRLFLHPKPQ

INTU

901

Q9ULD6
FQIPPWHLDRKYGSC

CCNYL3

6

P0C7X3
GIAVHTWYACPALIK

FRMD4A

291

Q9P2Q2
PWIRGNVYIHPTAKV

GMPPA

281

Q96IJ6
VSGWVKPIIIGRHAY

IDH1

121

O75874
CIIKPHYPAWVPVSV

IGSF3

566

O75054
GPIWKHATPVLNCFR

CABIN1

1116

Q9Y6J0
LLVCHVSGFYPKPVW

CD1D

221

P15813
HVAAGWSPDPKYQIC

DUSP15

206

Q9H1R2
PRKRYVYVWHCPQGP

FOXRED1

321

Q96CU9
LWFICLPAYVRVSHP

DENND4C

781

Q5VZ89
VWGLATHPYLPICAT

EML5

1001

Q05BV3
YCHGWRPAGQRVPSK

H1-9P

86

P60008
WTVKPHIGEVFCYLP

SACS

1861

Q9NZJ4
GWCKSYRPVSVAVIH

PROCA1

146

Q8NCQ7
LCSWVPALRRYKIHP

CH25H

61

O95992
PPRVWAVVDLYGKCT

NEURL4

186

Q96JN8
SFQRYLGICHPLAPW

P2RY6

121

Q15077
IKWFPEVTHFCRGIP

RHOF

111

Q9HBH0
SDYLPCAGVLIHPLW

PRSS58

36

Q8IYP2
TPKQHGTCPKGWLYF

PLA2R1

951

Q13018
KLRPPTCWGFTVVHE

ARAP1

1351

Q96P48
APFLCHPNLWIRYGA

PIK3R4

661

Q99570
LVKNWYREHCPAGQP

PRPF8

426

Q6P2Q9
FHLPEYTWRLPCGGV

TNIP1

591

Q15025
PFGRRLPCDIYWHGV

TTLL11

246

Q8NHH1
KEFWAVCRVPGPLHS

NEURL1

381

O76050
RYSDAWRVHQPGCKP

MEX3A

316

A1L020
NQRYGWHPATVCKIP

SMAD3

321

P84022
LWDKHACPAYVGPEI

TRIB3

216

Q96RU7
EIGWFPCNRVKPYVH

VAV1

646

P15498
CYPWFHGPISRVKAA

SH2B3

361

Q9UQQ2
ALYSLALRCWAPHPA

TNK1

351

Q13470
GIECQLWRSRYPHKP

F2

126

P00734
KRPEFVRGYNHPCGW

STARD4

141

Q96DR4
VAPSIAEPGWRACYK

TRAPPC9

416

Q96Q05
GPHLLAYRCLQWPAF

TM6SF2

346

Q9BZW4
EIIPCRIHLVWYPGK

RARRES1

246

P49788
WGCLYPIPREHLISL

ZFYVE26

1566

Q68DK2
IRHGLWICPFGKTSP

TMEM267

161

Q0VDI3
GPWLPECHNKVYLSG

TOE1

466

Q96GM8
HWVYVKRGGNCPAPT

ZBTB22

296

O15209
WEPCNHKPIGYNRFV

MYOM2

656

P54296