Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein tyrosine kinase activity	ERBB2 SRMS RYK JAK2 JAK3 PTK2B FER FGFR3 FGFR2 FGFR4	1.07e-07	145	145	10	GO:0004713
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	ERBB2 NEK6 POLH POLR2B POLR2L SRMS NOL9 TERT RYK GSK3B POLR3C JAK2 JAK3 PTK2B MAPKAPK3 FER PRKCA PRKCI FGFR3 FGFR2 FGFR4 NLK	1.14e-06	938	145	22	GO:0016772
GeneOntologyMolecularFunction	fibroblast growth factor receptor activity	FGFR3 FGFR2 FGFR4	3.71e-06	5	145	3	GO:0005007
GeneOntologyMolecularFunction	protein kinase activity	ERBB2 NEK6 SRMS RYK GSK3B JAK2 JAK3 PTK2B MAPKAPK3 FER PRKCA PRKCI FGFR3 FGFR2 FGFR4 NLK	7.76e-06	600	145	16	GO:0004672
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	ERBB2 NEK6 SRMS NOL9 RYK GSK3B JAK2 JAK3 PTK2B MAPKAPK3 FER PRKCA PRKCI FGFR3 FGFR2 FGFR4 NLK	1.59e-05	709	145	17	GO:0016773
GeneOntologyMolecularFunction	non-membrane spanning protein tyrosine kinase activity	SRMS JAK2 JAK3 PTK2B FER	2.03e-05	46	145	5	GO:0004715
GeneOntologyMolecularFunction	kinase activity	ERBB2 NEK6 SRMS NOL9 RYK GSK3B JAK2 JAK3 PTK2B MAPKAPK3 FER PRKCA PRKCI FGFR3 FGFR2 FGFR4 NLK	4.08e-05	764	145	17	GO:0016301
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	GLUD1 GLUD2	5.24e-05	2	145	2	GO:0016639
GeneOntologyMolecularFunction	glutamate dehydrogenase [NAD(P)+] activity	GLUD1 GLUD2	5.24e-05	2	145	2	GO:0004353
GeneOntologyMolecularFunction	glutamate dehydrogenase (NAD+) activity	GLUD1 GLUD2	5.24e-05	2	145	2	GO:0004352
GeneOntologyMolecularFunction	glutamate dehydrogenase (NADP+) activity	GLUD1 GLUD2	5.24e-05	2	145	2	GO:0004354
GeneOntologyMolecularFunction	tryptophan 5-monooxygenase activity	TPH2 TPH1	5.24e-05	2	145	2	GO:0004510
GeneOntologyMolecularFunction	5'-3' RNA polymerase activity	POLR2B POLR2L TERT POLR3C	8.19e-05	32	145	4	GO:0034062
GeneOntologyMolecularFunction	RNA polymerase activity	POLR2B POLR2L TERT POLR3C	8.19e-05	32	145	4	GO:0097747
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	ERBB2 RYK FGFR3 FGFR2 FGFR4	1.10e-04	65	145	5	GO:0004714
GeneOntologyMolecularFunction	RNA-dependent RNA polymerase activity	POLR2B TERT	1.56e-04	3	145	2	GO:0003968
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	ERBB2 RYK FGFR3 FGFR2 FGFR4	3.88e-04	85	145	5	GO:0019199
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors	LOXL2 GLUD1 GLUD2	3.91e-04	20	145	3	GO:0016638
GeneOntologyMolecularFunction	fibroblast growth factor binding	FGFR3 FGFR2 FGFR4	9.65e-04	27	145	3	GO:0017134
GeneOntologyMolecularFunction	L-leucine binding	GLUD1 GLUD2	1.07e-03	7	145	2	GO:0070728
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	TPH2 TPH1	1.07e-03	7	145	2	GO:0016714
GeneOntologyMolecularFunction	DNA-directed 5'-3' RNA polymerase activity	POLR2B POLR2L POLR3C	1.32e-03	30	145	3	GO:0003899
GeneOntologyBiologicalProcess	protein autophosphorylation	NEK6 SRMS GSK3B JAK2 PTK2B MAPKAPK3 FER PRKCA FGFR2 FGFR4 NLK	6.54e-07	228	145	11	GO:0046777
GeneOntologyCellularComponent	glutamatergic synapse	FRMPD4 RASGRF2 PHF24 SPTBN2 CC2D1A GRIK3 RYK GSK3B JAK2 PTK2B TENM4 IL1RAPL2 NTN1 PRKCI PACSIN2 KPNA1	1.94e-04	817	146	16	GO:0098978
GeneOntologyCellularComponent	intracellular protein-containing complex	KIF23 GTF2A1L JADE2 POLR2B POLR2L TERT KLHL20 GSK3B POLR3C AGO3 POP5 ARIH2 AHR ELP2 ANAPC5 TRAPPC9 ANAPC4	4.55e-04	972	146	17	GO:0140535
GeneOntologyCellularComponent	anchoring junction	ZNF384 KIF23 SPTBN2 ASAP3 AQP3 TSPAN33 JAK2 PTK2B FER PKP2 PRKCA PRKCI FGFR3 FGFR4 RPL7 BAIAP2L2 PACSIN2	4.76e-04	976	146	17	GO:0070161
GeneOntologyCellularComponent	endolysosome lumen	CTSL CTSS	4.78e-04	5	146	2	GO:0036021
GeneOntologyCellularComponent	nuclear protein-containing complex	RAD51B EXOSC10 GTF2A1L POLR2B POLR2L ARFGEF1 INTS3 TERT INTS8 HELB POLR3C POP5 SUPT16H AHR SMARCA4 SENP2 ELP2 TIMELESS ANAPC5 ANAPC4 KPNA1	5.93e-04	1377	146	21	GO:0140513
GeneOntologyCellularComponent	transcription factor TFIIIC complex	GTF3C5 GTF3C3	7.13e-04	6	146	2	GO:0000127
Domain	Tyr_kinase_cat_dom	ERBB2 SRMS RYK JAK2 JAK3 PTK2B FER FGFR3 FGFR2 FGFR4	1.91e-09	88	148	10	IPR020635
Domain	TyrKc	ERBB2 SRMS RYK JAK2 JAK3 PTK2B FER FGFR3 FGFR2 FGFR4	1.91e-09	88	148	10	SM00219
Domain	PROTEIN_KINASE_TYR	ERBB2 SRMS RYK JAK2 JAK3 PTK2B FER FGFR3 FGFR2 FGFR4	5.02e-09	97	148	10	PS00109
Domain	Tyr_kinase_AS	ERBB2 SRMS RYK JAK2 JAK3 PTK2B FER FGFR3 FGFR2 FGFR4	5.02e-09	97	148	10	IPR008266
Domain	Ser-Thr/Tyr_kinase_cat_dom	ERBB2 NEK6 SRMS RYK JAK2 JAK3 PTK2B FER FGFR3 FGFR2 FGFR4	1.29e-08	138	148	11	IPR001245
Domain	Pkinase_Tyr	ERBB2 SRMS RYK JAK2 JAK3 PTK2B FER FGFR3 FGFR2 FGFR4	7.91e-08	129	148	10	PF07714
Domain	Protein_kinase_ATP_BS	ERBB2 NEK6 SRMS GSK3B JAK2 JAK3 PTK2B MAPKAPK3 FER PRKCA PRKCI FGFR3 FGFR2 FGFR4 NLK	3.51e-07	379	148	15	IPR017441
Domain	PROTEIN_KINASE_ATP	ERBB2 NEK6 SRMS RYK GSK3B JAK2 JAK3 PTK2B MAPKAPK3 FER PRKCA PRKCI FGFR3 FGFR2 FGFR4 NLK	7.63e-07	459	148	16	PS00107
Domain	Prot_kinase_dom	ERBB2 NEK6 SRMS RYK GSK3B JAK2 JAK3 PTK2B MAPKAPK3 FER PRKCA PRKCI FGFR3 FGFR2 FGFR4 NLK	1.74e-06	489	148	16	IPR000719
Domain	PROTEIN_KINASE_DOM	ERBB2 NEK6 SRMS RYK GSK3B JAK2 JAK3 PTK2B MAPKAPK3 FER PRKCA PRKCI FGFR3 FGFR2 FGFR4 NLK	1.94e-06	493	148	16	PS50011
Domain	FGF_rcpt_fam	FGFR3 FGFR2 FGFR4	1.94e-06	4	148	3	IPR016248
Domain	Kinase-like_dom	ERBB2 NEK6 SRMS RYK GSK3B JAK2 JAK3 PTK2B MAPKAPK3 FER PRKCA PRKCI FGFR3 FGFR2 FGFR4 NLK	6.48e-06	542	148	16	IPR011009
Domain	ELFV_dehydrog_N	GLUD1 GLUD2	6.24e-05	2	148	2	PF02812
Domain	Glu/Leu/Phe/Val_DH_C	GLUD1 GLUD2	6.24e-05	2	148	2	IPR006096
Domain	Glu/Leu/Phe/Val_DH_dimer_dom	GLUD1 GLUD2	6.24e-05	2	148	2	IPR006097
Domain	Glu/Leu/Phe/Val_DH	GLUD1 GLUD2	6.24e-05	2	148	2	IPR006095
Domain	ELFV_dehydrog	GLUD1 GLUD2	6.24e-05	2	148	2	PF00208
Domain	NAD_bind_Glu_DH	GLUD1 GLUD2	6.24e-05	2	148	2	IPR033922
Domain	GLFV_DEHYDROGENASE	GLUD1 GLUD2	6.24e-05	2	148	2	PS00074
Domain	ELFV_dehydrog	GLUD1 GLUD2	6.24e-05	2	148	2	SM00839
Domain	Glu/Leu/Phe/Val_DH_AS	GLUD1 GLUD2	6.24e-05	2	148	2	IPR033524
Domain	Trp_5_mOase	TPH2 TPH1	6.24e-05	2	148	2	IPR005963
Domain	ACT_dom	TPH2 TPH1	1.86e-04	3	148	2	IPR002912
Domain	ACT	TPH2 TPH1	1.86e-04	3	148	2	PS51671
Domain	ACT	TPH2 TPH1	1.86e-04	3	148	2	PF01842
Domain	-	TPH2 TPH1	3.70e-04	4	148	2	1.10.800.10
Domain	ArAA_hydroxylase_Fe/CU_BS	TPH2 TPH1	3.70e-04	4	148	2	IPR018301
Domain	BH4_AAA_HYDROXYL_2	TPH2 TPH1	3.70e-04	4	148	2	PS51410
Domain	ArAA_hydroxylase	TPH2 TPH1	3.70e-04	4	148	2	IPR001273
Domain	Biopterin_H	TPH2 TPH1	3.70e-04	4	148	2	PF00351
Domain	Tyrosine_3-monooxygenase-like	TPH2 TPH1	3.70e-04	4	148	2	IPR019773
Domain	Aromatic-AA_hydroxylase_C	TPH2 TPH1	3.70e-04	4	148	2	IPR019774
Domain	Tyr_kinase_non-rcpt_Jak/Tyk2	JAK2 JAK3	3.70e-04	4	148	2	IPR016251
Domain	BH4_AAA_HYDROXYL_1	TPH2 TPH1	3.70e-04	4	148	2	PS00367
Domain	DAG/PE-bd	CHN1 PRKCA PRKCI	5.84e-04	21	148	3	IPR020454
Domain	PH_dom-like	FRMPD4 RASGRF2 DOCK11 SPTBN2 ASAP3 JAK2 JAK3 PTK2B PLD2 SPATA13 PHLPP2	5.96e-04	426	148	11	IPR011993
Domain	FERM_domain	FRMPD4 JAK2 JAK3 PTK2B	6.08e-04	49	148	4	IPR000299
Domain	FERM_1	FRMPD4 JAK2 JAK3 PTK2B	6.57e-04	50	148	4	PS00660
Domain	FERM_2	FRMPD4 JAK2 JAK3 PTK2B	6.57e-04	50	148	4	PS00661
Domain	FERM_3	FRMPD4 JAK2 JAK3 PTK2B	6.57e-04	50	148	4	PS50057
Domain	Band_41_domain	FRMPD4 JAK2 JAK3 PTK2B	6.57e-04	50	148	4	IPR019749
Domain	B41	FRMPD4 JAK2 JAK3 PTK2B	6.57e-04	50	148	4	SM00295
Domain	Prot_inhib_I29	CTSL CTSS	1.28e-03	7	148	2	IPR013201
Domain	Inhibitor_I29	CTSL CTSS	1.28e-03	7	148	2	PF08246
Domain	Inhibitor_I29	CTSL CTSS	1.28e-03	7	148	2	SM00848
Domain	-	TTC21A INTS8 GTF3C3 CFAP54 TTC29 ANAPC5 CLUH	1.33e-03	207	148	7	1.25.40.10
Domain	SH2	SRMS CHN1 JAK2 JAK3 FER	1.83e-03	110	148	5	SM00252
Domain	SH2	SRMS CHN1 JAK2 JAK3 FER	1.91e-03	111	148	5	PS50001
Domain	SH2	SRMS CHN1 JAK2 JAK3 FER	1.99e-03	112	148	5	IPR000980
Domain	-	SRMS CHN1 JAK2 JAK3 FER	1.99e-03	112	148	5	3.30.505.10
Domain	TPR_REGION	TTC21A INTS8 GTF3C3 TTC29 ANAPC5 CLUH	2.04e-03	165	148	6	PS50293
Domain	TPR	TTC21A INTS8 GTF3C3 TTC29 ANAPC5 CLUH	2.04e-03	165	148	6	PS50005
Domain	TPR-like_helical_dom	TTC21A INTS8 GTF3C3 CFAP54 TTC29 ANAPC5 CLUH	2.60e-03	233	148	7	IPR011990
Domain	Pept_asp_AS	CTSL CTSS	2.69e-03	10	148	2	IPR025661
Domain	Pept_his_AS	CTSL CTSS	3.27e-03	11	148	2	IPR025660
Domain	Pept_C1	CTSL CTSS	4.59e-03	13	148	2	SM00645
Domain	Peptidase_C1A_C	CTSL CTSS	4.59e-03	13	148	2	IPR000668
Domain	Peptidase_C1	CTSL CTSS	4.59e-03	13	148	2	PF00112
Domain	Peptidase_C1A	CTSL CTSS	4.59e-03	13	148	2	IPR013128
Domain	Ras_G-nucl-exch_fac_CS	RASGRF2 RASGEF1C	5.33e-03	14	148	2	IPR019804
Domain	FERM_central	FRMPD4 JAK2 PTK2B	6.88e-03	49	148	3	IPR019748
Domain	PH_DOMAIN	RASGRF2 DOCK11 SPTBN2 ASAP3 PLD2 SPATA13 PHLPP2	6.90e-03	279	148	7	PS50003
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL	ERBB2 FGFR3 FGFR2 FGFR4	3.38e-05	25	106	4	M47934
Pathway	WP_OSTEOARTHRITIC_CHONDROCYTE_HYPERTROPHY	JAK2 PRKCA FGFR3 FGFR2 FGFR4	3.54e-05	50	106	5	M48087
Pathway	WP_EGFR_TYROSINE_KINASE_INHIBITOR_RESISTANCE	ERBB2 GSK3B JAK2 PRKCA FGFR3 FGFR2	3.96e-05	84	106	6	M39839
Pathway	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_1_PROMOTER	POLR2L GTF3C5 GTF3C3 POLR3C	4.64e-05	27	106	4	MM15457
Pathway	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_1_PROMOTER	POLR2L GTF3C5 GTF3C3 POLR3C	5.38e-05	28	106	4	M27716
Pathway	REACTOME_SIGNALING_BY_FGFR_IN_DISEASE	POLR2B POLR2L FGFR3 FGFR2 FGFR4	1.09e-04	63	106	5	M635
Pathway	REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR	TLR3 CTSL CTSS	1.12e-04	13	106	3	M593
Pathway	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION	POLR2L GTF3C5 GTF3C3 POLR3C	1.18e-04	34	106	4	MM15435
Pathway	REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES	ERBB2 POLR2B POLR2L JAK2 JAK3 PTK2B MAPKAPK3 FER PRKCA FGFR3 FGFR2 FGFR4 TPH1	1.74e-04	532	106	13	M27870
Pathway	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION	POLR2L GTF3C5 GTF3C3 POLR3C	2.47e-04	41	106	4	M739
Pubmed	The protein tyrosine kinase family of the human genome.	ERBB2 SRMS RYK JAK2 JAK3 PTK2B FER FGFR3 FGFR2 FGFR4	3.05e-12	83	150	10	11114734
Pubmed	ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner.	ERBB2 JAK2 FGFR3 FGFR4	2.30e-08	8	150	4	11940572
Pubmed	The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex.	BTG2 ASPM PRKCA PRKCI	1.60e-07	12	150	4	22031545
Pubmed	FGFR1-4 RNA-Based Gene Alteration and Expression Analysis in Squamous Non-Small Cell Lung Cancer.	FGFR3 FGFR2 FGFR4	3.14e-07	4	150	3	36142417
Pubmed	Expression of basic fibroblast growth factor and its receptors in human ovarian follicles from adults and fetuses.	FGFR3 FGFR2 FGFR4	3.14e-07	4	150	3	16210019
Pubmed	Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9.	FGFR3 FGFR2 FGFR4	3.14e-07	4	150	3	9664689
Pubmed	The FGF system has a key role in regulating vascular integrity.	FGFR3 FGFR2 FGFR4	3.14e-07	4	150	3	18776942
Pubmed	The cytoplasmic tyrosine kinase Pyk2 as a novel effector of fibroblast growth factor receptor 3 activation.	PTK2B FGFR3 FGFR2	3.14e-07	4	150	3	15105428
Pubmed	Differential expression of the fibroblast growth factor receptor (FGFR) multigene family in normal human adult tissues.	FGFR3 FGFR2 FGFR4	3.14e-07	4	150	3	9212826
Pubmed	Immunohistochemical detection of fibroblast growth factor receptors in normal endocrine cells and related tumors of the digestive system.	FGFR3 FGFR2 FGFR4	3.14e-07	4	150	3	11759058
Pubmed	Differential expression of fibroblast growth factor receptors in the developing murine choroid plexus.	FGFR3 FGFR2 FGFR4	3.14e-07	4	150	3	12644244
Pubmed	Expression of fibroblast growth factor receptor family members is associated with prognosis in early stage cervical cancer patients.	FGFR3 FGFR2 FGFR4	3.14e-07	4	150	3	27154171
Pubmed	Amplification of FRS2 and activation of FGFR/FRS2 signaling pathway in high-grade liposarcoma.	FGFR3 FGFR2 FGFR4	3.14e-07	4	150	3	23393200
Pubmed	Immunolocalization of fibroblast growth factor receptors in normal and wounded human skin.	FGFR3 FGFR2 FGFR4	3.14e-07	4	150	3	12373339
Pubmed	RNAi-based conditional gene knockdown in mice using a U6 promoter driven vector.	FGFR3 FGFR2 FGFR4	3.14e-07	4	150	3	17304337
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	POLR2B HAT1 URB2 ANKHD1 GTF3C5 DARS2 ARIH2 SUPT16H SMARCA4 ANKRD17 PRKCI ELP2 TIMELESS TBC1D23 KPNA1	4.42e-07	704	150	15	29955894
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	NEK6 HIRIP3 GSK3B DARS2 JAK2 PTK2B AGO3 SUPT16H FER PRKCA PRKCI ANKRD36 FGFR3 FGFR2 FGFR4 ANAPC5 ANAPC4	4.55e-07	910	150	17	36736316
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RAD51B ERBB2 ZBTB20 NEK6 RHBDF2 JADE2 TTC21A RNF213 INTS3 INTS8 JAK2 BTG2 KCNQ5 LOXL2 XXYLT1 RASGEF1C ANKRD17 NTN1 PRKCI TRAPPC9 NLK KPNA1	4.66e-07	1489	150	22	28611215
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	EXOSC10 KIF23 DOCK11 POLR2B GTF3C3 SUPT16H SMARCA4 PKP2 ANKRD17 ANAPC5 ANAPC4 KPNA1	5.18e-07	440	150	12	34244565
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	ERBB2 ZBTB20 POLR2B SRMS BRD3 KLHL20 GSK3B GIPC3 PTK2B ARIH2 GBGT1 SMARCA4 PRKCA SENP2 PRKCI	6.95e-07	730	150	15	34857952
Pubmed	The human immunodeficiency virus tat protein increases the transcription of human Alu repeated sequences by increasing the activity of the cellular transcription factor TFIIIC.	POLR2L GTF3C5 GTF3C3 POLR3C	7.57e-07	17	150	4	1403646
Pubmed	Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference.	FGFR3 FGFR2 FGFR4	7.81e-07	5	150	3	15987787
Pubmed	Efficient regulation of branching morphogenesis via fibroblast growth factor receptor 2c in early-stage embryonic mouse salivary glands.	FGFR3 FGFR2 FGFR4	7.81e-07	5	150	3	27206683
Pubmed	Overlapping expression and redundant activation of mesenchymal fibroblast growth factor (FGF) receptors by alternatively spliced FGF-8 ligands.	FGFR3 FGFR2 FGFR4	7.81e-07	5	150	3	9013630
Pubmed	The mouse Fgfrl1 gene coding for a novel FGF receptor-like protein.	FGFR3 FGFR2 FGFR4	7.81e-07	5	150	3	11566361
Pubmed	The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes.	FGFR3 FGFR2 FGFR4	7.81e-07	5	150	3	27078042
Pubmed	Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors.	FGFR3 FGFR2 FGFR4	7.81e-07	5	150	3	16091423
Pubmed	FGF-dependent regulation of VEGF receptor 2 expression in mice.	FGFR3 FGFR2 FGFR4	7.81e-07	5	150	3	21633168
Pubmed	Expression of fibroblast growth factor receptors in peri-implantation mouse embryos.	FGFR3 FGFR2 FGFR4	7.81e-07	5	150	3	9771645
Pubmed	Persistent fibroblast growth factor 23 signalling in the parathyroid glands for secondary hyperparathyroidism in mice with chronic kidney disease.	FGFR3 FGFR2 FGFR4	7.81e-07	5	150	3	28094278
Pubmed	Fgfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault.	FGFR3 FGFR2 FGFR4	1.56e-06	6	150	3	10572038
Pubmed	Somatic mutation of epidermal growth factor receptor in a small subset of cutaneous squamous cell carcinoma.	ERBB2 FGFR3 FGFR2	1.56e-06	6	150	3	19812598
Pubmed	Evidence that the novel receptor FGFRL1 signals indirectly via FGFR1.	FGFR3 FGFR2 FGFR4	1.56e-06	6	150	3	24026051
Pubmed	Trans-activation of EphA4 and FGF receptors mediated by direct interactions between their cytoplasmic domains.	FGFR3 FGFR2 FGFR4	1.56e-06	6	150	3	16365308
Pubmed	Regulation of fibroblast growth factor-23 signaling by klotho.	FGFR3 FGFR2 FGFR4	1.56e-06	6	150	3	16436388
Pubmed	Neuron-derived FGF9 is essential for scaffold formation of Bergmann radial fibers and migration of granule neurons in the cerebellum.	FGFR3 FGFR2 FGFR4	1.56e-06	6	150	3	19232523
Pubmed	FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells.	FGFR3 FGFR2 FGFR4	1.56e-06	6	150	3	9010207
Pubmed	Central role of the proximal tubular αKlotho/FGF receptor complex in FGF23-regulated phosphate and vitamin D metabolism.	FGFR3 FGFR2 FGFR4	1.56e-06	6	150	3	29720668
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	FRMPD4 SPTBN2 SPOCK2 CACHD1 HSPA12A CLUH MEGF10	1.64e-06	130	150	7	12421765
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	EXOSC10 POLR2B SPTBN2 EMC9 DNAJC21 CC2D1A SPG11 NOL9 GTF3C3 DARS2 GSTM3 HSPA12A GLUD1 SUPT16H ASPM SENP2 PRKCI ELP2 CLUH RPL7 PACSIN2	1.79e-06	1487	150	21	33957083
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	SRMS URB2 TMEM129 LOXL2 SUPT16H SMARCA4 FGFR3 OTULINL CTSL SLC25A45	1.97e-06	332	150	10	37433992
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	ERBB2 EXOSC10 KIF23 POLR2B POLR2L RNF213 ANKHD1 GTF3C5 GTF3C3 SUPT16H FAM167A SMARCA4 RPL7	2.28e-06	601	150	13	33658012
Pubmed	Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction.	JAK2 FGFR3 FGFR4	2.72e-06	7	150	3	8626374
Pubmed	FGF as a target-derived chemoattractant for developing motor axons genetically programmed by the LIM code.	FGFR3 FGFR2 FGFR4	2.72e-06	7	150	3	16772167
Pubmed	Activin and basic fibroblast growth factor regulate neurogenesis of murine embryonal carcinoma cells.	FGFR3 FGFR2 FGFR4	2.72e-06	7	150	3	8959336
Pubmed	Expression patterns of FGF receptors in the developing mammalian cochlea.	FGFR3 FGFR2 FGFR4	2.72e-06	7	150	3	20131355
Pubmed	Putative tyrosine kinases expressed in K-562 human leukemia cells.	RYK FGFR3 FGFR4	2.72e-06	7	150	3	2247464
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	POLR2L CC2D1A BRD3 NOL9 NDUFA10 INTS3 GTF3C3 POLR3C SUPT16H SMARCA4 FAHD1 ANAPC5	3.78e-06	533	150	12	30554943
Pubmed	Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.	SLC25A14 SPOCK2 PRKCA PRKCI FGFR3 FGFR2 FGFR4 PACSIN2	3.90e-06	210	150	8	16537572
Pubmed	Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation.	JAK2 FGFR3 FGFR2 FGFR4	3.92e-06	25	150	4	11294897
Pubmed	A protein interaction landscape of breast cancer.	RAD51B ERBB2 SPTBN2 GSTM3 SCUBE2 LOXL2 SUPT16H AHR SMARCA4 CLUH RPL7 ANAPC4 KPNA1	4.07e-06	634	150	13	34591612
Pubmed	betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c.	FGFR3 FGFR2 FGFR4	4.33e-06	8	150	3	18187602
Pubmed	Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21.	FGFR3 FGFR2 FGFR4	4.33e-06	8	150	3	17623664
Pubmed	Syndecan-4 dependent FGF stimulation of mouse vibrissae growth.	FGFR3 FGFR2 FGFR4	4.33e-06	8	150	3	16989989
Pubmed	Phosphorylation and activation of the DNA binding activity of purified Stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptor.	JAK2 FGFR3 FGFR4	4.33e-06	8	150	3	7657660
Pubmed	Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III.	GTF3C5 GTF3C3 POLR3C	4.33e-06	8	150	3	10373544
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	POLR2B DNAJC21 NOL9 ANKHD1 DARS2 AGO3 GLUD1 ASPM PKP2 KPNA1	4.46e-06	364	150	10	24778252
Pubmed	ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation.	POLR2B POLR2L GSK3B SUPT16H SMARCA4	5.79e-06	59	150	5	34108663
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	EXOSC10 POLR2B HAT1 NOL9 NDUFA10 GTF3C5 PKP2 ELP2 TIMELESS ANAPC5 CLUH KPNA1	6.23e-06	560	150	12	35241646
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	STARD13 ZNF384 EXOSC10 KIF23 POLR2B URB2 NOL9 ANKHD1 GTF3C5 GTF3C3 GSK3B SUPT16H ASPM SMARCA4 PKP2 ANKRD17 PRKCA RPL7 KPNA1	6.30e-06	1353	150	19	29467282
Pubmed	Integration of FGF and TWIST in calvarial bone and suture development.	FGFR3 FGFR2 FGFR4	6.48e-06	9	150	3	10751173
Pubmed	Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination.	FGFR3 FGFR2 FGFR4	6.48e-06	9	150	3	15229180
Pubmed	Activation of protein kinase C delta by IFN-gamma.	JAK2 FGFR3 FGFR4	6.48e-06	9	150	3	12817007
Pubmed	Hypertonicity activates Na+/H+ exchange through Janus kinase 2 and calmodulin.	JAK2 FGFR3 FGFR4	6.48e-06	9	150	3	12626508
Pubmed	Expression of Fgf receptors 1, 2, and 3 in the developing mid- and hindbrain of the mouse.	FGFR3 FGFR2 FGFR4	6.48e-06	9	150	3	15830353
Pubmed	Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development.	FGFR3 FGFR2 FGFR4	6.48e-06	9	150	3	31613912
Pubmed	The expression of fibroblast growth factors and their receptors in the embryonic and neonatal mouse inner ear.	FGFR3 FGFR2 FGFR4	6.48e-06	9	150	3	11335076
Pubmed	Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain.	JAK2 FGFR3 FGFR4	9.23e-06	10	150	3	12244095
Pubmed	Laminar patterning in the developing neocortex by temporally coordinated fibroblast growth factor signaling.	FGFR3 FGFR2 FGFR4	9.23e-06	10	150	3	15470137
Pubmed	Regulation of external genitalia development by concerted actions of FGF ligands and FGF receptors.	FGFR3 FGFR2 FGFR4	9.23e-06	10	150	3	15340846
Pubmed	A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma.	JAK2 FGFR3 FGFR4	9.23e-06	10	150	3	7690989
Pubmed	Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels.	NTN1 FGFR3 FGFR2 FGFR4	9.55e-06	31	150	4	22076636
Pubmed	Protein kinase Cdelta regulates apoptosis via activation of STAT1.	JAK2 FGFR3 FGFR4	1.26e-05	11	150	3	15322115
Pubmed	Fibroblast growth factor signalling in the hair growth cycle: expression of the fibroblast growth factor receptor and ligand genes in the murine hair follicle.	FGFR3 FGFR2 FGFR4	1.26e-05	11	150	3	8901049
Pubmed	Fgf20 is required for sensory epithelial specification in the developing cochlea.	FGFR3 FGFR2 FGFR4	1.26e-05	11	150	3	18524904
Pubmed	Dlg-1 Interacts With and Regulates the Activities of Fibroblast Growth Factor Receptors and EphA2 in the Mouse Lens.	FGFR3 FGFR2 FGFR4	1.26e-05	11	150	3	26906157
Pubmed	The murine gene, Traube, is essential for the growth of preimplantation embryos.	FGFR3 FGFR2 FGFR4	1.26e-05	11	150	3	11071758
Pubmed	Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation.	JAK2 FGFR3 FGFR4	1.26e-05	11	150	3	7543024
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ZNF384 KIF23 HIRIP3 POLH HAT1 BRD3 GTF3C5 GTF3C3 SUPT16H SMARCA4 TIMELESS KPNA1	1.41e-05	608	150	12	36089195
Pubmed	Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.	ERBB2 JAK2 SMARCA4 FGFR3 FGFR2	1.44e-05	71	150	5	28319113
Pubmed	FGF signaling gradient maintains symmetrical proliferative divisions of midbrain neuronal progenitors.	BTG2 PRKCI FGFR3 FGFR2	1.57e-05	35	150	4	21074523
Pubmed	Immunohistochemical study of genesis of the mouse oral vestibule.	FGFR3 FGFR2 FGFR4	1.68e-05	12	150	3	14964469
Pubmed	Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures.	FGFR3 FGFR2 FGFR4	1.68e-05	12	150	3	10751172
Pubmed	The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity.	GTF3C5 GTF3C3 POLR3C	1.68e-05	12	150	3	10523658
Pubmed	Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling.	FGFR3 FGFR2 FGFR4	1.68e-05	12	150	3	12460940
Pubmed	Mapping of murine fibroblast growth factor receptors refines regions of homology between mouse and human chromosomes.	FGFR3 FGFR2 FGFR4	1.68e-05	12	150	3	7959747
Pubmed	Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4.	JAK2 FGFR3 FGFR4	1.68e-05	12	150	3	10918587
Pubmed	Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3) and phospho-Stat3 (Tyr705) in node-negative breast cancer shows nuclear localization is associated with a better prognosis.	JAK2 FGFR3 FGFR4	1.68e-05	12	150	3	12576423
Pubmed	The roles of FGF signaling in germ cell migration in the mouse.	FGFR3 FGFR2 FGFR4	1.68e-05	12	150	3	16291796
Pubmed	Ser727/Tyr701-phosphorylated Stat1 is required for the regulation of c-Myc, cyclins, and p27Kip1 associated with ATRA-induced G0/G1 arrest of U-937 cells.	JAK2 FGFR3 FGFR4	1.68e-05	12	150	3	12637327
Pubmed	Attention-deficit/hyperactivity disorder symptoms in offspring of mothers with impaired serotonin production.	TPH2 TPH1	1.85e-05	2	150	2	20921119
Pubmed	Cancer gene profiling in non-small cell lung cancers reveals activating mutations in JAK2 and JAK3 with therapeutic implications.	JAK2 JAK3	1.85e-05	2	150	2	29082853
Pubmed	Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulation.	GLUD1 GLUD2	1.85e-05	2	150	2	28621566
Pubmed	DNA damage stress and inhibition of Jak2-V617F cause its degradation and synergistically induce apoptosis through activation of GSK3β.	GSK3B JAK2	1.85e-05	2	150	2	22087308
Pubmed	GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior.	GLUD1 GLUD2	1.85e-05	2	150	2	32078638
Pubmed	Human cathepsin S, but not cathepsin L, degrades efficiently MHC class II-associated invariant chain in nonprofessional APCs.	CTSL CTSS	1.85e-05	2	150	2	12748383
Pubmed	Glycogen Synthase Kinase 3 Beta Regulates the Human Aryl Hydrocarbon Receptor Cellular Content and Activity.	GSK3B AHR	1.85e-05	2	150	2	34198826
Pubmed	Prognostic impact of FGFR2/3 alterations in patients with biliary tract cancers receiving systemic chemotherapy: the BITCOIN study.	FGFR3 FGFR2	1.85e-05	2	150	2	35303508
Pubmed	Common variants in the TPH1 and TPH2 regions are not associated with persistent ADHD in a combined sample of 1,636 adult cases and 1,923 controls from four European populations.	TPH2 TPH1	1.85e-05	2	150	2	20213726
Pubmed	Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.	GLUD1 GLUD2	1.85e-05	2	150	2	28911206
Interaction	FGF17 interactions	ANKHD1 ANKRD17 NTN1 FGFR3 FGFR2 FGFR4	7.34e-07	44	146	6	int:FGF17
Interaction	RELB interactions	NEK6 KLHL20 GSK3B SMARCA4 CTBS CTSL KPNA1	1.56e-06	78	146	7	int:RELB
Interaction	GRM1 interactions	ERBB2 TTYH2 TERT PTK2B PRKCA FGFR4	5.74e-06	62	146	6	int:GRM1
Interaction	SRC interactions	ERBB2 HIRIP3 POLR2B POLR2L SRMS TERT JAK2 PTK2B KCNQ5 AHR PRKCA PRKCI FGFR2 FGFR4 PLD2 OTULINL CTSL	6.60e-06	664	146	17	int:SRC
Interaction	FGF3 interactions	URB2 ANKHD1 ANKRD17 FGFR3 FGFR2 FGFR4	8.29e-06	66	146	6	int:FGF3
Interaction	FKBP5 interactions	POLR2B SRMS DNAJC21 URB2 GSK3B GSTM3 JAK3 AGO3 FER ELP2 PLD2 ANAPC5 PHLPP2	1.03e-05	414	146	13	int:FKBP5
Interaction	FGF6 interactions	FGFR3 FGFR2 FGFR4	1.28e-05	7	146	3	int:FGF6
Interaction	FGF18 interactions	FGFR3 FGFR2 FGFR4	1.28e-05	7	146	3	int:FGF18
Interaction	POLR3C interactions	POLR2L BRD3 GTF3C5 GTF3C3 POLR3C SMARCA4 KPNA1	1.55e-05	110	146	7	int:POLR3C
Interaction	FGF5 interactions	FGFR3 FGFR2 FGFR4	2.03e-05	8	146	3	int:FGF5
Interaction	FGF23 interactions	FGFR3 FGFR2 FGFR4	2.03e-05	8	146	3	int:FGF23
Interaction	STAT3 interactions	ERBB2 JAK2 JAK3 PTK2B GLUD1 FER SMARCA4 ELP2 FGFR3 FGFR2 FGFR4 NLK KPNA1	2.26e-05	446	146	13	int:STAT3
Interaction	POLR3A interactions	POLR2B POLR2L BRD3 GTF3C3 POLR3C JAK3 SMARCA4 PKP2	2.52e-05	163	146	8	int:POLR3A
Interaction	IKBKG interactions	KIF23 POLR2B SPTBN2 TTYH2 ASAP3 GSK3B GSTM3 JAK2 JAK3 TLR3 SENP2 PRKCI KPNA1	2.98e-05	458	146	13	int:IKBKG
Interaction	SSRP1 interactions	ZNF384 EXOSC10 KIF23 HIRIP3 POLR2B BRD3 INTS3 INTS8 KLHL20 GSK3B LOXL2 SUPT16H SMARCA4 TIMELESS FGFR2 CTSL	3.82e-05	685	146	16	int:SSRP1
Interaction	IL4R interactions	ERBB2 RHBDF2 JAK2 JAK3 ARIH2	4.04e-05	53	146	5	int:IL4R
Interaction	PPP3CA interactions	RNF213 RYK GSK3B HSPA12A FAM167A FGFR4 CLUH PHLPP2	4.92e-05	179	146	8	int:PPP3CA
Interaction	AP5M1 interactions	SPG11 GTF3C3 HSPA12A	7.81e-05	12	146	3	int:AP5M1
Interaction	KLB interactions	FGFR3 FGFR2 FGFR4	7.81e-05	12	146	3	int:KLB
Interaction	TICAM2 interactions	ERBB2 RHBDF2 GSK3B TLR3	8.12e-05	32	146	4	int:TICAM2
Interaction	PTGES3 interactions	KIF23 POLR2B CC2D1A NOL9 TERT GTF3C5 JAK3 AGO3 AHR PLD2 TBC1D23 PACSIN2	8.34e-05	437	146	12	int:PTGES3
Interaction	PTPN12 interactions	GSK3B JAK2 PTK2B PRKCA FGFR2 FGFR4 PACSIN2	9.10e-05	145	146	7	int:PTPN12
Interaction	PHIP interactions	KIF23 BRD3 ANKHD1 AGO3 SUPT16H SMARCA4 PKP2 ANKRD17	9.64e-05	197	146	8	int:PHIP
Interaction	TOP2A interactions	KIF23 DNAJC21 BRD3 MBD6 KLHL20 GSK3B LOXL2 GLUD1 SMARCA4 PRKCA CLUH RPL7 KPNA1	1.08e-04	520	146	13	int:TOP2A
Interaction	HYOU1 interactions	ERBB2 TMEM129 LOXL2 PRKCA FGFR3 FGFR4 TBC1D23 CTSL CTSS RPL7	1.08e-04	317	146	10	int:HYOU1
Interaction	HSP90AA1 interactions	STARD13 ERBB2 ZBTB20 TTC21A POLH SRMS SPG11 TERT GSK3B JAK2 JAK3 PTK2B AGO3 LOXL2 FER AHR PRKCA PRKCI FGFR3 FGFR4 SDR16C5 RPL7	1.12e-04	1263	146	22	int:HSP90AA1
Interaction	ACBD3 interactions	ERBB2 RHBDF2 ARFGEF1 RYK PRKCI FGFR3 FGFR2 FGFR4 OTULINL	1.16e-04	259	146	9	int:ACBD3
Interaction	KL interactions	FGFR3 FGFR2 FGFR4	1.28e-04	14	146	3	int:KL
Interaction	MACROH2A1 interactions	ERBB2 KIF23 HIRIP3 POLR2B BRD3 NOL9 GTF3C3 KLHL20 LOXL2 SUPT16H SMARCA4 FGFR3	1.30e-04	458	146	12	int:MACROH2A1
Interaction	ELOF1 interactions	POLR2B POLR2L GSK3B SUPT16H SMARCA4	1.65e-04	71	146	5	int:ELOF1
Interaction	H3-3B interactions	BRD3 GSK3B LOXL2 SUPT16H SMARCA4 TIMELESS	1.83e-04	114	146	6	int:H3-3B
Interaction	FGF7 interactions	FGFR3 FGFR2 FGFR4	1.95e-04	16	146	3	int:FGF7
Interaction	FGF9 interactions	FGFR3 FGFR2 FGFR4	1.95e-04	16	146	3	int:FGF9
Interaction	BAG5 interactions	POLR2B RNF213 ANKHD1 GSTM3 AGO3 AHR FGFR3 PLD2 CTSS RPL7	1.95e-04	341	146	10	int:BAG5
Interaction	CISH interactions	ERBB2 JAK2 JAK3 PRKCA	1.97e-04	40	146	4	int:CISH
Interaction	PTPN6 interactions	ERBB2 EXOSC10 JAK2 JAK3 PTK2B PRKCA FGFR2 FGFR4 RPL7	1.98e-04	278	146	9	int:PTPN6
Interaction	PIK3R1 interactions	ERBB2 KIF23 JAK2 JAK3 PTK2B TLR3 FER SMARCA4 FGFR3 FGFR2 FGFR4	2.12e-04	412	146	11	int:PIK3R1
Interaction	PTK2B interactions	ERBB2 JAK2 JAK3 PTK2B FGFR3 FGFR2	2.31e-04	119	146	6	int:PTK2B
Interaction	POLR1G interactions	ZNF384 EXOSC10 POLR2B POLR2L BRD3 URB2 NOL9 GTF3C5 GTF3C3 SUPT16H SMARCA4 KPNA1	2.37e-04	489	146	12	int:POLR1G
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	RYK FGFR3 FGFR2 FGFR4	8.05e-05	40	104	4	321
GeneFamily	RNA polymerase subunits	POLR2B POLR2L POLR3C	6.06e-04	29	104	3	726
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASGRF2 DOCK11 SPTBN2 ASAP3 SPATA13 PHLPP2	1.22e-03	206	104	6	682
GeneFamily	SH2 domain containing	SRMS CHN1 JAK2 FER	2.75e-03	101	104	4	741
GeneFamily	Anaphase promoting complex \|Tetratricopeptide repeat domain containing	ANAPC5 ANAPC4	2.85e-03	14	104	2	402
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	FRMPD4 JAK2 PTK2B	2.98e-03	50	104	3	1293
GeneFamily	Integrator complex	INTS3 INTS8	3.28e-03	15	104	2	1366
GeneFamily	Cathepsins	CTSL CTSS	3.28e-03	15	104	2	470
ToppCell	LV-16._Neuronal\|World / Chamber and Cluster_Paper	GRIK3 FAM135B HSPA12A IL1RAPL2 RASGEF1C AHR PRKCA MEGF10	9.33e-08	165	150	8	6ed52cb756d21addf46c7f6c457458b01339fe04
ToppCell	LA-16._Neuronal\|World / Chamber and Cluster_Paper	GRIK3 FAM135B HSPA12A IL1RAPL2 RASGEF1C AHR PRKCA MEGF10	1.07e-07	168	150	8	2fd1fd2a16ac1c5eb028f93cc3a2477c7747693e
ToppCell	LA-16._Neuronal\|LA / Chamber and Cluster_Paper	GRIK3 FAM135B HSPA12A IL1RAPL2 RASGEF1C AHR PRKCA MEGF10	1.07e-07	168	150	8	c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCell	LV-16._Neuronal\|LV / Chamber and Cluster_Paper	GRIK3 FAM135B HSPA12A IL1RAPL2 RASGEF1C AHR PRKCA MEGF10	1.12e-07	169	150	8	a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCell	RA-16._Neuronal\|RA / Chamber and Cluster_Paper	GRIK3 FAM135B HSPA12A IL1RAPL2 RASGEF1C AHR PRKCA MEGF10	1.82e-07	180	150	8	5842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 RAD51B SPTBN2 AQP3 BTG2 TMEM45B IL1RAPL2 PRKCA	2.75e-07	190	150	8	11d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 RAD51B SPTBN2 BTG2 TMEM45B IL1RAPL2 PRKCA NLK	2.75e-07	190	150	8	b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACHD1 AQP3 TENM4 KCNQ5 EDARADD PKP2 NTN1 FGFR2	3.62e-07	197	150	8	1e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GRIK3 FAM135B NWD2 FAM167A RASGEF1C PRKCA NTN1	1.55e-06	166	150	7	6a6ed5c7a43fee9a8a9be42dfa99303815b8e8ef
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	STARD13 GRIK3 HSPA12A IL1RAPL2 RASGEF1C PRKCA MEGF10	1.68e-06	168	150	7	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	Control-Epithelial_cells-Airway_basal\|Control / group, cell type (main and fine annotations)	RAD51B FRMPD4 CACHD1 EDARADD NTN1 FGFR3 FGFR2	1.89e-06	171	150	7	3965ced4be6db14265a90673502fceee425837ca
ToppCell	COVID-19-Heart-Neuronal\|Heart / Disease (COVID-19 only), tissue and cell type	STARD13 GRIK3 HSPA12A IL1RAPL2 RASGEF1C PRKCA MEGF10	2.04e-06	173	150	7	6fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAMTSL1 CHN1 BTG2 IL1RAPL2 PRKCI FGFR3 FGFR2	2.56e-06	179	150	7	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	RA-16._Neuronal\|World / Chamber and Cluster_Paper	GRIK3 FAM135B HSPA12A RASGEF1C AHR PRKCA MEGF10	2.75e-06	181	150	7	7d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 RAD51B SPTBN2 AQP3 BTG2 TMEM45B PRKCA	2.96e-06	183	150	7	d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RAD51B ZBTB20 TTYH2 FGFR3 FGFR2 MEGF10 SPATA13	3.18e-06	185	150	7	b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 SPTBN2 AQP3 FCGBP TMEM45B FGFR2 KLKB1	3.54e-06	188	150	7	315ce1736e3a84a63a8d5dfa70d411b501cb2532
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 RAD51B SPTBN2 AQP3 BTG2 IL1RAPL2 PRKCA	3.54e-06	188	150	7	e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RAD51B ZBTB20 TTYH2 FGFR3 FGFR2 MEGF10 SPATA13	3.66e-06	189	150	7	42ab4cc5fbf8580841f31889446fe4499df1a464
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB2 SPTBN2 AQP3 BTG2 TMEM45B IL1RAPL2 RPL7	3.92e-06	191	150	7	0a0719a0a49ae0099d61e22585ac74c10c24b4a2
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RAD51B ZBTB20 TTYH2 FGFR3 FGFR2 MEGF10 SPATA13	3.92e-06	191	150	7	2b056cbe2e82e056e1f798974999378460eb1d16
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RHBDF2 TTC21A RNF213 GBGT1 OTULINL KLKB1 CTSS	4.06e-06	192	150	7	935a4a36881a9fa4daa02cba96af07f6686ed8d6
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RASGRF2 SPOCK2 CACHD1 GSTM3 FCGBP PRKCA SLC25A45	4.06e-06	192	150	7	ad2e0f35d50fe4e6977eba8a7a2bd990f6946305
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	RASGRF2 SPOCK2 CACHD1 GSTM3 FCGBP PRKCA SLC25A45	4.06e-06	192	150	7	284955fec5103194d416320f41fa4d87c7efc4fb
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRF2 SPOCK2 CACHD1 GSTM3 FCGBP PRKCA SLC25A45	4.06e-06	192	150	7	0d3b2b9cd586a4adbc3755563dd50b140227c287
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRF2 SPOCK2 CACHD1 GSTM3 FCGBP PRKCA SLC25A45	4.06e-06	192	150	7	67f50e5b1d449923002dc5b5d0c4d32c523034d3
ToppCell	COVID-19-kidney-CD-PC\|kidney / Disease (COVID-19 only), tissue and cell type	RAD51B SPTBN2 AQP3 ZNF676 BTG2 TMEM45B PRKCA	4.20e-06	193	150	7	738689d009e4b118d7ce3171a207294b95cbe78b
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB20 GRIK3 RYR3 TENM4 FGFR4 RPL7 MEGF10	4.20e-06	193	150	7	1aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RAD51B ADAMTSL1 CHN1 SCUBE2 IL1RAPL2 NTN1 FGFR3	4.97e-06	198	150	7	6ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACHD1 AQP3 TENM4 KCNQ5 EDARADD NTN1 FGFR3	4.97e-06	198	150	7	5374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD8+_T_naive\|COVID-19_Mild / Disease, condition lineage and cell class	RASGRF2 SPOCK2 CACHD1 GSTM3 FCGBP PRKCA SLC25A45	5.31e-06	200	150	7	7192138e2704c030d70561bcd59259fb3ad82f06
ToppCell	RV-16._Neuronal\|World / Chamber and Cluster_Paper	GRIK3 FAM135B HSPA12A IL1RAPL2 RASGEF1C PRKCA	1.15e-05	149	150	6	3a2f8c4173dcf9e3f8d3b8ffddbc597098adf7a9
ToppCell	RV-16._Neuronal\|RV / Chamber and Cluster_Paper	GRIK3 FAM135B HSPA12A IL1RAPL2 RASGEF1C PRKCA	1.34e-05	153	150	6	bed8bbf5c5cbfbf46a816066da472c3fdddecb5d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell-Schwann_Cell_/_Neural-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TTYH2 GRIK3 IL1RAPL2 RASGEF1C MEGF10 PDZD4	1.39e-05	154	150	6	30cb4bb297fa815adb829f3b5cafca56fcbcb810
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell-Schwann_Cell_/_Neural\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TTYH2 GRIK3 IL1RAPL2 RASGEF1C MEGF10 PDZD4	1.39e-05	154	150	6	ade094e2947761a0a34daa8fcff3e9ea8437e4a5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TTYH2 GRIK3 IL1RAPL2 RASGEF1C MEGF10 PDZD4	1.39e-05	154	150	6	42bd8f88fd075a2d4edde394785decad88a2660a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TTYH2 GRIK3 IL1RAPL2 RASGEF1C MEGF10 PDZD4	1.39e-05	154	150	6	6425d9861148586466febd6eceae1b1f9b9a14c1
ToppCell	PND07-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 PHF24 GSTM3 OTULINL PADI1 TPH1	1.73e-05	160	150	6	5d22c86deead516444349d495998e04586be4396
ToppCell	PND07-Immune-Immune_Myeloid-Granulocytic-Mast\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 PHF24 GSTM3 OTULINL PADI1 TPH1	1.73e-05	160	150	6	ca212634cf1875238071d1800ecdf34979a553fb
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZBTB20 DOCK11 GRIK3 LHX6 EDARADD TIMELESS	1.79e-05	161	150	6	bf70be1de418615b5442ec684552551edaf1f072
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRMPD4 GTF3C5 TIMM10 TTC29 ASPM MAPKBP1	2.12e-05	166	150	6	43f84d3cd58e93ce00c241656c4cba27604b4932
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RASGRF2 GRIK3 IL1RAPL2 GLUD2 NTN1 MEGF10	2.20e-05	167	150	6	49b19159c62d33d65ed1e59a148c11ae902fd41c
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	ERBB2 POLH GTF3C3 KLHL20 PRKCI CLUH	2.27e-05	168	150	6	8697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10\|TCGA-Brain / Sample_Type by Project: Shred V9	RYR3 CFAP54 TTC29 TLR3 DNAI4 PADI1	2.51e-05	171	150	6	74be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEK6 PRKCA CTSL CTSS PADI1 PDZD4	3.25e-05	179	150	6	1757b9f3f4c634277a67c4f5a39d27d6b4937073
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEK6 PRKCA CTSL CTSS PADI1 PDZD4	3.35e-05	180	150	6	64f01494a4052186773720e10b4e7c724ff94547
ToppCell	facs-Marrow-B-cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEK6 PRKCA CTSL CTSS PADI1 PDZD4	3.45e-05	181	150	6	782716b8b1d447d2bbe09a693fa5ed7ebeac0efb
ToppCell	facs-Marrow-B-cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEK6 PRKCA CTSL CTSS PADI1 PDZD4	3.45e-05	181	150	6	e2481291c236105774c53883e6f20da11941df9b
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEK6 PRKCA CTSL CTSS PADI1 PDZD4	3.45e-05	181	150	6	fb64da1dde37fe6ba7de2586cd58848ac1974f24
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 SPTBN2 AQP3 BTG2 IL1RAPL2 PRKCA	3.45e-05	181	150	6	b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RASGRF2 GRIK3 IL1RAPL2 RASGEF1C NTN1 MEGF10	3.45e-05	181	150	6	fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEK6 PRKCA CTSL CTSS PADI1 PDZD4	3.56e-05	182	150	6	33afbb7c4352b03266501b1f4f0e751c12c7350d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 RAD51B SPTBN2 AQP3 IL1RAPL2 PRKCA	3.67e-05	183	150	6	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RASGRF2 GRIK3 IL1RAPL2 RASGEF1C NTN1 MEGF10	3.67e-05	183	150	6	e0854864d377e158a4793088d1cb6b3dbf2c805d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SPOCK2 AQP3 HELB PRKCA ANKRD36 SPATA13	3.67e-05	183	150	6	f2ef110bf29b1a8276ef216238363e542db262c1
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RASGRF2 DOCK11 GRIK3 LHX6 TTC29 AHR	3.79e-05	184	150	6	7f6c8912677764d438ab0555faca344d74c2f483
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 RAD51B SPTBN2 TMEM45B IL1RAPL2 PRKCA	3.90e-05	185	150	6	d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCell	Control-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	RAD51B ADAMTSL1 HELB KCNQ5 AHR NTN1	3.90e-05	185	150	6	6814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-Th1\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF213 SPOCK2 CHN1 JAK3 MAPKAPK3 ASPM	3.90e-05	185	150	6	326c8b6ea0e9140616d7b867db1385b980dc3678
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RASGRF2 GRIK3 IL1RAPL2 RASGEF1C NTN1 MEGF10	3.90e-05	185	150	6	56c7a0dbf141728ac76b8c90af197719942ca67c
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEK6 PRKCA CTSL CTSS PADI1 PDZD4	3.90e-05	185	150	6	65dcb0a7ee64990a34a87c167b44497107f035ee
ToppCell	5'-Adult-LargeIntestine-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STARD13 GRIK3 HSPA12A IL1RAPL2 RASGEF1C MEGF10	3.90e-05	185	150	6	f607b6ee579562e2f92103fa5c7053df0170a229
ToppCell	5'-Adult-LargeIntestine-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STARD13 GRIK3 HSPA12A IL1RAPL2 RASGEF1C MEGF10	3.90e-05	185	150	6	317f2c854f00aa5957319b818c85eeed7d72ec7f
ToppCell	5'-Adult-LargeIntestine-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STARD13 GRIK3 HSPA12A IL1RAPL2 RASGEF1C MEGF10	3.90e-05	185	150	6	7bb8fdfe04f85d25056380ec58222366de323a21
ToppCell	PCW_07-8.5-Neuronal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RASGRF2 GRIK3 IL1RAPL2 RASGEF1C NTN1 MEGF10	4.02e-05	186	150	6	7a4bb42f3f6a27b463e48eafc587d9ab3386f2fb
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RASGRF2 DOCK11 GRIK3 LHX6 ASPM FGFR2	4.02e-05	186	150	6	6379609b7ace80683f5754b16aa77f11b43766ae
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	STARD13 KIF23 GRIK3 LHX6 IL1RAPL2	4.05e-05	113	150	5	feb3c6a7723263d58e5ce020a0097fedfcf78ca8
ToppCell	10x5'v1-week_17-19-Lymphocytic_T-T_NK-NK_T_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	RNF213 SPOCK2 AQP3 JAK3 FCGBP SLC25A45	4.14e-05	187	150	6	3301e0fca8c436d136c71f1a8fd59b3bb11bdd83
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZBTB20 TTYH2 FGFR3 FGFR2 MEGF10 SPATA13	4.14e-05	187	150	6	97e520705491c8f52a32025311a9fa7b9176979a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 SPTBN2 AQP3 IL1RAPL2 PRKCA NTN1	4.14e-05	187	150	6	2d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 RAD51B SPTBN2 TMEM45B IL1RAPL2 PRKCA	4.14e-05	187	150	6	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 HIRIP3 CHN1 TENM4 LOXL2 ASPM	4.27e-05	188	150	6	95d0a796d62ce6d121e2028c378faffc14b35275
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RASGRF2 SPOCK2 LHX6 ASPM PKP2 ATP11C	4.27e-05	188	150	6	3139540a656c0436b2123ea50741ff8d00112165
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 SPTBN2 AQP3 TMEM45B IL1RAPL2 PRKCA	4.40e-05	189	150	6	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTC21A CFAP54 TTC29 FAM167A DNAI4 TEKT4	4.40e-05	189	150	6	02c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCell	cellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ASAP3 CHN1 LHX6 KLHL20 POLR3C CDADC1	4.40e-05	189	150	6	bccb3481ffed597c845fe860da658505316105b5
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_3\|Classical_Monocyte / Disease condition and Cell class	ANKHD1 POLR3C GLUD2 GBGT1 SENP2 FAHD1	4.40e-05	189	150	6	8b6f92ccfffc743c07201bc971b3dc1a6fa14ccc
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTC21A CFAP54 TTC29 FAM167A DNAI4 TEKT4	4.40e-05	189	150	6	164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCell	PND10-Epithelial-Epithelial_Airway\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTC21A CFAP54 TTC29 FAM167A DNAI4 TEKT4	4.40e-05	189	150	6	407d8a59969d83f014600aae1a55092283a13970
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHF24 CHN1 RYR3 PTK2B KCNQ5 RASGEF1C	4.40e-05	189	150	6	3e8e30160a8d6f531ff743cb5918c9e79481f1bd
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_3\|COVID-19_Convalescent / Disease condition and Cell class	ANKHD1 POLR3C GLUD2 GBGT1 SENP2 FAHD1	4.40e-05	189	150	6	732e8dcffcb634ca2968f9170c9c4b31dd5d4206
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RAD51B SPTBN2 AQP3 BTG2 TMEM45B IL1RAPL2	4.40e-05	189	150	6	bfc76a72b600d641c8fe58346e5d8986c34f3981
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHF24 CHN1 RYR3 PTK2B KCNQ5 RASGEF1C	4.40e-05	189	150	6	851f8144aed5c7f80302911cd6b03f14bde7b56d
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTC21A CFAP54 TTC29 FAM167A DNAI4 TEKT4	4.40e-05	189	150	6	a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 AQP3 BTG2 IL1RAPL2 EDARADD PRKCA	4.40e-05	189	150	6	532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZBTB20 TTYH2 FGFR3 FGFR2 MEGF10 SPATA13	4.40e-05	189	150	6	37ecbd73408d462b47d7e5611f203143e08a2689
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	RAD51B SCUBE2 AHR NTN1 FGFR3 FGFR2	4.53e-05	190	150	6	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZBTB20 TTYH2 FGFR3 FGFR2 MEGF10 SPATA13	4.53e-05	190	150	6	07f21386ea6eb23416a537d2250e3042efe93fb0
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 SPTBN2 AQP3 TMEM45B FGFR2 KLKB1	4.53e-05	190	150	6	c408d4033a130c0168159a5b6f286fd2b2a9a39d
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD4 SPTBN2 AQP3 TMEM45B FGFR2 KLKB1	4.53e-05	190	150	6	d4910c37045a8b8bb53b37625263bc0a47b6e3f8
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZBTB20 TTYH2 FGFR3 FGFR2 MEGF10 SPATA13	4.53e-05	190	150	6	ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB2 SPTBN2 AQP3 TMEM45B IL1RAPL2 PRKCA	4.53e-05	190	150	6	078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTC21A CFAP54 TTC29 FAM167A DNAI4 TEKT4	4.66e-05	191	150	6	bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTC21A CFAP54 TTC29 FAM167A DNAI4 TEKT4	4.66e-05	191	150	6	6880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN2 AQP3 GSTM3 BTG2 TMEM45B IL1RAPL2	4.66e-05	191	150	6	7235a4d1601c88a2c8af571a2c04ab56d32f1b9a
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RASGRF2 SPOCK2 AQP3 HELB PRKCA LRRC75A	4.66e-05	191	150	6	142f98cabf8737b28369315b3d7a0797ded88e03
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD4-positive,_alpha-beta_T_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SPOCK2 GSTM3 TMEM45B PRKCA LRRC75A RPL7	4.66e-05	191	150	6	363fd576de11615bf5953f5e3f82f1b1c5083001
ToppCell	COPD-Myeloid-DC_Mature\|Myeloid / Disease state, Lineage and Cell class	TTYH2 TSPAN33 LOXL2 EDARADD ATP11C NTN1	4.80e-05	192	150	6	baebd462f464e7d0e462d07a74bb5d685a9fc3b6
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	HELB JAK3 DNAI4 PRKCA OTULINL SPATA13	4.80e-05	192	150	6	1c0ce299cee9ab5cdea256f3e8c1e5598577a8b6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RAD51B SPTBN2 AQP3 BTG2 IL1RAPL2 PRKCA	4.80e-05	192	150	6	fd08ae787e936cfdb1ab8f19b0fd63005b462709
Computational	Genes in the cancer module 85.	ERBB2 RYK FGFR3 FGFR2 FGFR4	7.46e-05	51	93	5	MODULE_85
Computational	Genes in the cancer module 199.	ERBB2 RYK FGFR3 FGFR2 FGFR4	1.28e-04	57	93	5	MODULE_199
Drug	3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-(4-(4-ethylpiperazin-1-yl)-phenylamino)pyrimidin-4-yl)-1-methylurea	FGFR3 FGFR2 FGFR4	1.09e-06	4	149	3	ctd:C568950
Drug	AC1L1O6Q	ERBB2 RYK JAK2 PTK2B KCNQ5 PRKCA PRKCI PLD2	4.23e-06	141	149	8	CID000058035
Drug	GSK-3beta Inhibitor VIII; Down 200; 10uM; PC3; HT_HG-U133A	STARD13 RHBDF2 SLC25A14 GTF3C5 RYK POLR3C JAK2 TENM4 SENP2	4.84e-06	191	149	9	7070_DN
Drug	Palifermin	FGFR3 FGFR2 FGFR4	5.41e-06	6	149	3	DB00039
Drug	ponatinib	JAK2 JAK3 PTK2B FGFR3 FGFR2 FGFR4	5.56e-06	68	149	6	ctd:C545373
Drug	SB216763	GSK3B JAK2 JAK3 AHR PRKCA	6.14e-06	40	149	5	CID000176158
Drug	AC1N4HBY	GSK3B GLUD1 GLUD2	2.24e-05	9	149	3	CID004128835
Drug	FLA 365	RYR3 LOXL2 AHR	2.24e-05	9	149	3	CID000072776
Drug	C-1A	ARFGEF1 PTK2B PRKCA PRKCI CTSL CTSS	2.99e-05	91	149	6	CID009543473
Drug	glycerol	DUSP28 POLR2B SLC25A14 SPTBN2 POLR2L AQP3 GSK3B PTK2B EDARADD GLUD1 TLR3 GLUD2 SUPT16H PRKCA PRKCI PLD2 KLKB1	3.15e-05	829	149	17	CID000000753
Drug	NmiQ	LOXL2 GLUD1 GLUD2	3.19e-05	10	149	3	CID000019850
Drug	bisindolylmaleimide V	GSK3B PTK2B PRKCA PRKCI	3.19e-05	28	149	4	CID000002400
Drug	0-to	ERBB2 TERT JAK2 PTK2B PRKCA PRKCI FGFR2	4.06e-05	141	149	7	CID000002051
Drug	phenyltriethoxysilane	GLUD1 GLUD2	4.25e-05	2	149	2	CID000013075
Drug	SC-48274	TPH2 TPH1	4.25e-05	2	149	2	CID000040914
Drug	G-3SH	GLUD1 GLUD2	4.25e-05	2	149	2	CID000174237
Drug	iodoacetyldiethylstilbestrol	GLUD1 GLUD2	4.25e-05	2	149	2	CID006455327
Drug	3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile	JAK2 JAK3	4.25e-05	2	149	2	DB08183
Drug	methylmercuric bromide	GLUD1 GLUD2	4.25e-05	2	149	2	CID000068175
Drug	5-methylisophthalate	GLUD1 GLUD2	4.25e-05	2	149	2	CID000068137
Drug	alpha-difluoromethyldopa	TPH2 TPH1	4.25e-05	2	149	2	CID000129677
Drug	3-(5-(4-(2-hydroxy-2-methylpropionyl)piperazin-1-yl)-2-trifluoromethylphenyl)-4-(1H-indol-3-yl)pyrrole-2,5-dione	GSK3B JAK3	4.25e-05	2	149	2	ctd:C562244
Drug	x 1 s	GLUD1 GLUD2	4.25e-05	2	149	2	CID000409694
Drug	2-(1,1-DIMETHYLETHYL)9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLIN-7-ONE	JAK2 JAK3	4.25e-05	2	149	2	DB04716
Drug	GW2974	ERBB2 GSK3B PTK2B	4.36e-05	11	149	3	CID006603857
Drug	Tetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; PC3; HT_HG-U133A	RAD51B RHBDF2 ASAP3 LOXL2 ZNF253 CDADC1 PRKCA FGFR4	4.62e-05	196	149	8	4587_DN
Drug	LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A	RAD51B ARIH2 PRKCA TIMELESS FGFR2 FGFR4 PLD2 NLK	4.96e-05	198	149	8	6935_UP
Drug	Antipyrine, 4-hydroxy [1672-63-5]; Up 200; 19.6uM; PC3; HG-U133A	POLR2B SPOCK2 AKIP1 BTG2 IL1RAPL2 ARIH2 FER CTBS	5.14e-05	199	149	8	1915_UP
Drug	Nalidixic acid sodium salt hydrate; Up 200; 14.6uM; MCF7; HT_HG-U133A	TERT BTG2 TENM4 LOXL2 PRKCA FGFR4 CTSS TRAPPC9	5.14e-05	199	149	8	2297_UP
Drug	PD 166285	JAK2 FGFR3 FGFR2	5.79e-05	12	149	3	CID005311382
Drug	Methylthioacetylaminoethanol	GLUD1 GLUD2 CTBS	5.79e-05	12	149	3	CID000155653
Drug	thiopental	GTF2A1L RYR3 IL1RAPL2 PRKCA PRKCI TRAPPC9	9.60e-05	112	149	6	CID003000715
Drug	UTP-NA	POLR2B POLR2L GTF3C5 GTF3C3 POLR3C PTK2B GBGT1 SUPT16H PRKCA PLD2 NLK	1.05e-04	420	149	11	CID000001181
Drug	mono-(2-ethylhexyl)phthalate	RASGRF2 SPTBN2 TTYH2 BRD3 GSK3B PTK2B BTG2 FCGBP LOXL2 MAPKAPK3 RASGEF1C AHR PRKCA CTSL	1.11e-04	658	149	14	ctd:C016599
Drug	NSC20261	POLH POLR2B POLR2L TERT GTF3C5 GTF3C3 POLR3C SUPT16H	1.17e-04	224	149	8	CID000000593
Drug	GTP - Na	STARD13 RASGRF2 POLR2B POLR2L CHN1 GTF3C5 GTF3C3 POLR3C PTK2B GLUD1 GLUD2 SUPT16H PRKCA PRKCI PLD2 RPL7 TPH1	1.18e-04	923	149	17	CID000000762
Drug	MFMD	LOXL2 TPH2 TPH1	1.18e-04	15	149	3	CID000122302
Drug	4-methyl-alpha-ethyl-m-tyramine	TPH2 TPH1	1.27e-04	3	149	2	CID000168028
Drug	lenthionine	GLUD1 GLUD2	1.27e-04	3	149	2	CID000067521
Drug	Fmtrp	TPH2 TPH1	1.27e-04	3	149	2	CID000126435
Drug	mildiomycin	GLUD1 GLUD2	1.27e-04	3	149	2	CID000125665
Drug	5-iodonicotinic acid	ERBB2 RYK	1.27e-04	3	149	2	CID000151950
Drug	2-hydroxy-4,5-methylenedioxyamphetamine	TPH2 TPH1	1.27e-04	3	149	2	CID000126859
Drug	methoxyethylmercury	GLUD1 GLUD2	1.27e-04	3	149	2	CID000115155
Drug	4-methylumbelliferyl laurate	GLUD1 GLUD2	1.27e-04	3	149	2	CID000600674
Drug	2,4,5-trihydroxymethamphetamine	TPH2 TPH1	1.27e-04	3	149	2	CID000131985
Drug	1-hexadecanesulfonyl chloride	TERT GBGT1	1.27e-04	3	149	2	CID000096923
Drug	2,4,5-trihydroxyamphetamine	TPH2 TPH1	1.27e-04	3	149	2	CID000126234
Drug	methylmercuric iodide	GLUD1 GLUD2	1.27e-04	3	149	2	CID000067347
Drug	AC1Q5QKX	TPH2 TPH1	1.27e-04	3	149	2	CID000164302
Drug	forsythoside A	SUPT16H PRKCA	1.27e-04	3	149	2	CID004484391
Drug	lavendustin A	SRMS RYR3 JAK2 AHR PRKCA PRKCI FGFR2	1.37e-04	171	149	7	CID000003894
Drug	AC1O517G	TERT PRKCA CTSL	1.44e-04	16	149	3	CID006450188
Disease	bone disease (implicated_via_orthology)	FGFR3 FGFR2 FGFR4	1.20e-06	5	147	3	DOID:0080001 (implicated_via_orthology)
Disease	high grade glioma (implicated_via_orthology)	PRKCI FGFR3 FGFR2 FGFR4 MAPKBP1	2.66e-06	44	147	5	DOID:3070 (implicated_via_orthology)
Disease	oral squamous cell carcinoma (is_implicated_in)	TERT GSK3B FGFR3 FGFR4	1.10e-05	28	147	4	DOID:0050866 (is_implicated_in)
Disease	brain ischemia (biomarker_via_orthology)	AQP3 BTG2 GLUD1 GLUD2 PRKCA CTSL	1.25e-05	102	147	6	DOID:2316 (biomarker_via_orthology)
Disease	Isolated coronal synostosis	FGFR3 FGFR2	2.47e-05	2	147	2	cv:CN043619
Disease	Malignant neoplasm of breast	RAD51B ERBB2 RASGRF2 POLH DNAJC21 GRIK3 TERT ZNF404 IL1RAPL2 LOXL2 AHR TEKT4 TIMELESS FGFR2 PLD2 ANAPC5 PDZD4	2.68e-05	1074	147	17	C0006142
Disease	Lacrimoauriculodentodigital syndrome	FGFR3 FGFR2	7.37e-05	3	147	2	C0265269
Disease	Levy-Hollister syndrome	FGFR3 FGFR2	7.37e-05	3	147	2	cv:C0265269
Disease	fascioliasis (biomarker_via_orthology)	GLUD1 GLUD2	7.37e-05	3	147	2	DOID:885 (biomarker_via_orthology)
Disease	Saethre-Chotzen Syndrome	FGFR3 FGFR2	7.37e-05	3	147	2	C0175699
Disease	Congenital hypoplasia of radius	FGFR3 FGFR2	7.37e-05	3	147	2	C0685381
Disease	lung adenocarcinoma (is_implicated_in)	ERBB2 TERT JAK2 FGFR4	1.05e-04	49	147	4	DOID:3910 (is_implicated_in)
Disease	TWIST1-related craniosynostosis	FGFR3 FGFR2	1.47e-04	4	147	2	cv:C4551902
Disease	Psychotic Disorders	GRIK3 TENM4 TPH2 PRKCA FGFR2	1.55e-04	101	147	5	C0033975
Disease	CHGA cleavage product measurement	RAD51B KLKB1	2.44e-04	5	147	2	EFO_0007909
Disease	Mental Depression	GRIK3 GSK3B TPH2 PRKCI TIMELESS FGFR2 TPH1	2.95e-04	254	147	7	C0011570
Disease	QT interval	RASGRF2 JADE2 ASAP3 ARIH2 FAM167A PKP2 PRKCA SENP2 CLUH CTSS	3.61e-04	534	147	10	EFO_0004682
Disease	childhood absence epilepsy (biomarker_via_orthology)	GLUD1 GLUD2	3.65e-04	6	147	2	DOID:1825 (biomarker_via_orthology)
Disease	cerebral cortex growth measurement	ADAMTSL1 SPATA13	3.65e-04	6	147	2	EFO_0009328
Disease	stomach cancer (is_implicated_in)	ERBB2 JAK2 FGFR2 FGFR4	4.68e-04	72	147	4	DOID:10534 (is_implicated_in)
Disease	Schizophrenia	SPTBN2 GRIK3 LHX6 GSK3B HSPA12A TENM4 TLR3 TPH2 PRKCA FGFR2 MEGF10 KPNA1 TPH1	4.94e-04	883	147	13	C0036341
Disease	disease of cellular proliferation (implicated_via_orthology)	JAK2 JAK3	5.09e-04	7	147	2	DOID:14566 (implicated_via_orthology)
Disease	Craniosynostosis syndrome	FGFR3 FGFR2	5.09e-04	7	147	2	cv:C0010278
Disease	urinary bladder cancer (is_implicated_in)	ERBB2 TERT FGFR3 FGFR2	5.74e-04	76	147	4	DOID:11054 (is_implicated_in)
Disease	Adenocarcinoma of lung (disorder)	ERBB2 TIMM10 AHR FGFR3 FGFR2 FGFR4	6.02e-04	206	147	6	C0152013
Disease	Depressive disorder	GRIK3 GSK3B TPH2 PRKCI TIMELESS FGFR2 TPH1	6.38e-04	289	147	7	C0011581
Disease	cervical cancer	TERT JAK2 FGFR3	6.47e-04	34	147	3	C4048328
Disease	Uterine Cervical Neoplasm	TERT JAK2 FGFR3	7.05e-04	35	147	3	C0007873
Disease	stomach cancer (is_marker_for)	TERT JAK2 ASPM FGFR2 FGFR4	7.43e-04	142	147	5	DOID:10534 (is_marker_for)
Disease	Cardiomegaly	GSK3B AHR PRKCA PLD2	7.65e-04	82	147	4	C0018800
Disease	Cardiac Hypertrophy	GSK3B AHR PRKCA PLD2	7.65e-04	82	147	4	C1383860
Disease	Colorectal Carcinoma	RASGRF2 SPTBN2 ASAP3 ARFGEF1 HAT1 GRIK3 GSTM3 KCNQ5 ATP11C FGFR3 ANAPC4	8.14e-04	702	147	11	C0009402
Disease	bile salt-activated lipase measurement	GTF3C5 GBGT1	8.67e-04	9	147	2	EFO_0801425
Disease	ductal carcinoma in situ (is_marker_for)	ERBB2 TERT PRKCA	9.71e-04	39	147	3	DOID:0060074 (is_marker_for)
Disease	skin microbiome measurement	NEK6 CFAP54 OTULINL	9.71e-04	39	147	3	EFO_0801228
Disease	clonal hematopoiesis	TERT JAK2	1.08e-03	10	147	2	EFO_0010819
Disease	Head and Neck Carcinoma	ERBB2 FGFR2	1.08e-03	10	147	2	C3887461
Disease	high grade glioma (is_implicated_in)	ERBB2 GSTM3 PRKCA	1.21e-03	42	147	3	DOID:3070 (is_implicated_in)
Disease	Cleft palate, isolated	RYK FGFR3 FGFR2	1.21e-03	42	147	3	C1837218
Disease	nasopharynx carcinoma (is_marker_for)	TERT JAK2 FGFR4	1.29e-03	43	147	3	DOID:9261 (is_marker_for)
Disease	Gastric cancer	ERBB2 FGFR2	1.32e-03	11	147	2	cv:C0024623
Disease	Neoplasm of stomach	ERBB2 FGFR2	1.32e-03	11	147	2	cv:C0038356
Disease	GASTRIC CANCER	ERBB2 FGFR2	1.32e-03	11	147	2	613659
Disease	JT interval	JADE2 PKP2 PRKCA SENP2 CLUH CTSS	1.56e-03	248	147	6	EFO_0007885
Disease	craniosynostosis (is_implicated_in)	FGFR3 FGFR2	1.57e-03	12	147	2	DOID:2340 (is_implicated_in)
Disease	Myeloproliferative disease	TERT JAK2	1.57e-03	12	147	2	C0027022
Disease	prostate carcinoma	RAD51B ADAMTSL1 ZBTB20 NEK6 RNF213 TERT SCUBE2 PRKCI ANKRD36 FGFR2 KLKB1 PHLPP2	1.73e-03	891	147	12	EFO_0001663
Disease	hematologic cancer (implicated_via_orthology)	JAK2 JAK3	1.85e-03	13	147	2	DOID:2531 (implicated_via_orthology)
Disease	level of Sphingomyelin (d34:2) in blood serum	SMARCA4 ANKRD17	1.85e-03	13	147	2	OBA_2045174
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	SMARCA4 ANKRD17	2.16e-03	14	147	2	EFO_0004611, EFO_0008589
Disease	lung carcinoma, estrogen-receptor negative breast cancer, ovarian endometrioid carcinoma, colorectal cancer, prostate carcinoma, ovarian serous carcinoma, breast carcinoma, ovarian carcinoma, lung adenocarcinoma, squamous cell lung carcinoma	RAD51B TERT FGFR2	2.24e-03	52	147	3	EFO_0000305, EFO_0000571, EFO_0000708, EFO_0001071, EFO_0001075, EFO_0001663, EFO_1000650, EFO_1001515, EFO_1001516, MONDO_0005575
Disease	Glioblastoma Multiforme	TERT MAPKAPK3 PRKCA NLK	2.34e-03	111	147	4	C1621958
Disease	Rhabdomyosarcoma	TIMM10 FGFR4	2.48e-03	15	147	2	C0035412
Disease	hepatic encephalopathy (biomarker_via_orthology)	GLUD1 GLUD2	2.48e-03	15	147	2	DOID:13413 (biomarker_via_orthology)
Disease	Small cell carcinoma of lung	GRIK3 FER SMARCA4	2.49e-03	54	147	3	C0149925
Disease	complement factor H-related protein 1 measurement	FRMPD4 ZNF676 ASPM	2.77e-03	56	147	3	EFO_0600054
Disease	colorectal mucinous adenocarcinoma	ZBTB20 RASGRF2	2.83e-03	16	147	2	EFO_0009361
Disease	level of Sterol ester (27:1/18:1) in blood serum	SMARCA4 ANKRD17	2.83e-03	16	147	2	OBA_2045195
Disease	alcohol use disorder (implicated_via_orthology)	ERBB2 RYR3 SMARCA4 PRKCA CTSL	3.00e-03	195	147	5	DOID:1574 (implicated_via_orthology)
Disease	hypothyroidism	RAD51B NEK6 TERT EDARADD TLR3 SPATA13	3.08e-03	284	147	6	EFO_0004705
Disease	Benign neoplasm of stomach	ERBB2 FGFR2	3.19e-03	17	147	2	C0153943
Disease	plasma beta-amyloid 1-40 measurement	STARD13 TTC29	3.19e-03	17	147	2	EFO_0005659
Disease	Neoplasm of uncertain or unknown behavior of stomach	ERBB2 FGFR2	3.19e-03	17	147	2	C0496905
Disease	Multiple congenital anomalies	GSK3B FGFR2	3.19e-03	17	147	2	C0000772
Disease	Brachycephaly	FGFR3 FGFR2	3.19e-03	17	147	2	C0221356
Disease	Carcinoma in situ of stomach	ERBB2 FGFR2	3.19e-03	17	147	2	C0154060
Disease	a disintegrin and metalloproteinase with thrombospondin motifs 13 measurement	GBGT1 KLKB1	3.19e-03	17	147	2	EFO_0008011
Disease	Acute myeloid leukemia	TERT JAK2	3.19e-03	17	147	2	cv:C0023467
Disease	LEUKEMIA, ACUTE MYELOID	TERT JAK2	3.19e-03	17	147	2	601626
Disease	level of Sphingomyelin (d34:1) in blood serum	SMARCA4 ANKRD17	3.58e-03	18	147	2	OBA_2045175
Disease	Hereditary Diffuse Gastric Cancer	ERBB2 ZBTB20 FCGBP AHR FGFR2 CTSL	3.58e-03	293	147	6	C1708349
Disease	vital capacity	ADAMTSL1 JADE2 POLR2B SPTBN2 KCNQ5 FER CDADC1 AHR SENP2 FGFR2 FGFR4 MAPKBP1 SDR16C5 ANAPC4	3.58e-03	1236	147	14	EFO_0004312
Disease	autoimmune thyroid disease	RAD51B EDARADD TLR3 SPATA13	3.70e-03	126	147	4	EFO_0006812
Disease	Stomach Neoplasms	ERBB2 ZBTB20 FCGBP AHR FGFR2 CTSL	3.83e-03	297	147	6	C0038356
Disease	Prostatic Neoplasms	ERBB2 ZBTB20 JADE2 TERT GSK3B GSTM3 JAK2 AHR FGFR4	3.84e-03	616	147	9	C0033578
Disease	Malignant neoplasm of prostate	ERBB2 ZBTB20 JADE2 TERT GSK3B GSTM3 JAK2 AHR FGFR4	3.84e-03	616	147	9	C0376358
Disease	transitional cell carcinoma (is_marker_for)	ERBB2 TERT FGFR2	3.87e-03	63	147	3	DOID:2671 (is_marker_for)
Disease	renal cell carcinoma (is_marker_for)	ERBB2 TERT BTG2 PLD2	3.91e-03	128	147	4	DOID:4450 (is_marker_for)
Disease	glomerulonephritis (is_marker_for)	PTK2B KLKB1	3.99e-03	19	147	2	DOID:2921 (is_marker_for)
Disease	Malignant neoplasm of stomach	ERBB2 ZBTB20 FCGBP AHR FGFR2 CTSL	4.02e-03	300	147	6	C0024623
Disease	bone mineral content measurement	PTK2B RASGEF1C PRKCI MEGF10	4.13e-03	130	147	4	EFO_0007621
Disease	Global developmental delay	FRMPD4 SPTBN2 GTF3C3 SUPT16H	4.48e-03	133	147	4	C0557874
Disease	hearing loss	RPL7 BAIAP2L2 MEGF10	4.60e-03	67	147	3	EFO_0004238
Disease	ovarian neoplasm	ERBB2 TERT AQP3 SMARCA4	4.60e-03	134	147	4	C0919267
Disease	Stomach Carcinoma	ERBB2 FGFR2	4.86e-03	21	147	2	C0699791
Disease	Malignant neoplasm of ovary	ERBB2 TERT AQP3 SMARCA4	4.98e-03	137	147	4	C1140680

Protein segments in the cluster

Peptide	Gene	Start	Entry
VLKCARLVERMYSHI	URB2	1421	Q14146
LYCAESHIRMIKTGE	AHR	331	P35869
VCYGLGMEHLREVRA	ERBB2	341	P04626
HLRYCDSILREMLSK	BRD3	311	Q15059
IFLYCRRAMVLAHRG	CFAP54	1616	Q96N23
RRIFQLHMCEYLLKA	ASAP3	186	Q8TDY4
LEDSLYKMCILRRHT	ANAPC4	591	Q9UJX5
MEAIRLIRHCAKYVS	ARFGEF1	1341	Q9Y6D6
VARGMQYLESRKCIH	FGFR4	596	P22455
VYRYHRGESKLHMCL	AKIP1	116	Q9NQ31
IRCFIMEDRGYLVAH	CACHD1	836	Q5VU97
VGCRHYEVAKMLREL	GIPC3	166	Q8TF64
RQMYHAPTDCATIRK	ARIH2	261	O95376
RHCTYLENGMQDSRK	ANKRD36	1831	A6QL64
HCMVQARLLAYRTED	CDADC1	321	Q9BWV3
THCGTMRRKYRVCNV	AGO3	271	Q9H9G7
TLACYKGHLEMVRFL	ANKRD17	406	O75179
LMCYAHSKGARVVLK	CTBS	91	Q01459
KRAIMELERSTGYHL	DISP1	891	Q96F81
AAVCTAYLMRHRGLS	DUSP28	111	Q4G0W2
AGRKQCMEYIELRHA	ASPM	1936	Q8IZT6
HRKMSELLYHLTRCG	NWD2	831	Q9ULI1
HARRCRFNMELYKLS	NTN1	346	O95631
YRGVHELLCMVSRAC	RAD51B	46	O15315
LYVCRVMDTHGSNEK	PADI1	306	Q9ULC6
CKMAREAGATRVHAY	SDR16C5	81	Q8N3Y7
EDMKGIPFHRIRCIY	C9orf64	326	Q5T6V5
KCYRDLALVSRDGMN	INTS3	106	Q68E01
TRDLVYILMAKGLHC	INTS8	566	Q75QN2
CKGMEYLGTKRYIHR	JAK2	961	O60674
GMEYLGSRRCVHRDL	JAK3	936	P52333
YHTLGKTQERNRCAM	ANAPC5	721	Q9UJX4
RHGEKTMYRRKSQCC	MEGF10	81	Q96KG7
ARGMEYLASQKCIHR	FGFR2	611	P21802
CRGIDMEKRLYHILT	NOL9	611	Q5SY16
CNHRRKAVAMATLYR	MBD6	101	Q96DN6
HIKLTDYGMCKEGLR	PRKCI	391	P41743
VMRLKRYIRACGAHR	HIRIP3	426	Q9BW71
LDVYENMHHGKRCLL	MAPKAPK3	101	Q16644
GAMEKLCRQLTYHLS	LRRC75A	131	Q8NAA5
FRLMLETCYRLHGVD	KIAA2026	161	Q5HYC2
EQYSAGHLDMLCRIK	KCNQ5	551	Q9NR82
SNNIMKCRSRYDGHR	LOXL2	726	Q9Y4K0
YRHRAANLEKCMSEL	BAIAP2L2	126	Q6UXY1
LRYRVVLCIDHRGMH	ADAMTSL1	456	Q8N6G6
NLCYMVTRRERTKHA	JADE2	481	Q9NQC1
SSHRDKLGLMVCYRT	PDZD4	136	Q76G19
GEHYSEKLRELVSMC	NEK6	271	Q9HC98
TPHLKEAELMGRCYL	LMLN2	541	A0A1B0GTW7
CRIHYDTMIENLKRA	LHX6	181	Q9UPM6
VCVGRNYADHVREMR	FAHD1	21	Q6P587
LRYIARKHNMCGETE	GSTM3	81	P21266
AASIYCRKLRLHQMI	HSPA12A	241	O43301
YLDEGRLRYHTCMCK	NLK	426	Q9UBE8
MKCHYEALGVRRDAS	DNAJC21	1	Q5F1R6
CMEDLIHEIYTVGKR	RPL7	186	P18124
RGIHSSVQCKLRYGM	NDUFA10	26	O95299
IRDYHKRGSMCNTLF	OTULINL	216	Q9NUU6
MVRFKHRYLLCELVS	POP5	1	Q969H6
LMNCLHERARIEKAY	PACSIN2	41	Q9UNF0
RVMQYHGCRSNIKDR	EXOSC10	86	Q01780
MTCRGFREYHERLQT	HAT1	166	O14929
RRKHLGCAVYQDMIY	KLHL20	496	Q9Y2M5
LLEVCLFHFRYMGKR	DOCK11	1316	Q5JSL3
RVYEFTRGCHMAILA	GBGT1	271	Q8N5D6
GMLYLESKNCIHRDL	FER	671	P16591
QHYEGDRLCGMLTKL	FCGBP	666	Q9Y6R7
SMRYLHRFGAKCIAV	GLUD1	316	P00367
SVARLCDYHLAKRMS	FRMPD4	1186	Q14CM0
MRKLDHCNIVRLRYF	GSK3B	101	P49841
YGELTKLIRQQHEMC	CC2D1A	576	Q6P1N0
RQAVRLYHSVAGCKM	MAPKBP1	1431	O60336
GLDCYDLMRLKRTTA	DNAI4	626	Q5VTH9
VGQLMELCRLYHRAD	EDARADD	176	Q8WWZ3
CHRDIYKGVDMRGVN	KLKB1	111	P03952
MGRTVAVAEYGRCRH	KRTAP20-4	21	Q3LI62
EEGYIRMARNKGNHC	CTSS	306	P25774
ISALAYVKMCLHAAR	EMC9	6	Q9Y3B6
IHGYDLKCLAMINRF	ELP2	436	Q6IA86
DRYVPFHSARIEMCK	FAM135B	1316	Q49AJ0
VARGMEYLASQKCIH	FGFR3	601	P22607
LAECYGLRLKHMKSD	PTK2B	86	Q14289
CETLRYLMAHLKRVT	CHN1	391	P15882
MKRGREFRIIFDCSH	GRIK3	221	Q13003
PQYKMHTDGRSCLER	SCUBE2	241	Q9NQ36
CGMSYLARREVIHKD	RYK	451	P34925
SMRYLHRFGAKCIAV	GLUD2	316	P49448
IMYSRLKQICREDGH	HELB	296	Q8NG08
LLREDKNHNMYVAGC	KIF23	251	Q02241
TCRLHRRMLNDATYE	FAM167A	156	Q96KS9
LKYLDSMGQKGHRIC	SENP2	491	Q9HC62
KMREYLCNLHGFVDI	DARS2	196	Q6PI48
RKCHEANKRGGMYLE	STARD13	351	Q9Y3M8
CGMDHTEKRGRIYLK	PRKCA	151	P17252
DYICSPHAESMRKRN	RASGRF2	231	O14827
GVCRRLVELLMHNDY	KPNA1	296	P52294
SMQIRHCCRGYKHEI	IL1RAPL2	611	Q9NP60
IKCDMSALQRVLYRH	SMARCA4	996	P51532
TCQGMRHAIYDKLDD	POLR2B	836	P30876
LFIDRQKCMAHRTRY	TEKT4	411	Q8WW24
LRRCCALTRYDAHKM	POLH	381	Q9Y253
RAQAKVCHYRVSMAA	SRMS	161	Q9H3Y6
LRHGVKICDVYNAVM	SUPT16H	316	Q9Y5B9
TRVFHDGCLRRMGYI	PHF24	151	Q9UPV7
RHAECLKALGYMERA	GTF3C3	461	Q9Y5Q9
KGSGYRCIRINHKMD	BTG2	61	P78543
YVKMAKDRRNHCGIA	CTSL	311	P07711
LTLACYKGHLDMVRF	ANKHD1	376	Q8IWZ3
ELVSRCGEMLHIRYR	AQP3	6	Q92482
ACLRLLARLHYIMGD	CLUH	1021	O75153
VHVERNAMDGYRTLC	ATP11C	586	Q8NB49
YIRQCRKHTGMFTVA	SPATA13	266	Q96N96
RLHNMKLSISYLREC	SPG11	1351	Q96JI7
PYRKHSEEMICRLES	RNF213	2526	Q63HN8
LVYCLLTRMKRHGRG	TMEM45B	236	Q96B21
EIKYRGMFHALFRIC	SLC25A14	81	O95258
ENCYNRLMGSVKDHL	TIMELESS	351	Q9UNS1
KISDLDHCANRVLMY	TPH1	111	P17752
YARLMKHAEAALACL	TSPAN33	46	Q86UF1
HQKDGKTYRCRMCSL	ZNF384	221	Q8TF68
ECGKACRYMADVIRH	ZNF599	231	Q96NL3
PDYKLNHALCLRRGM	TLR3	856	O15455
MILRRYDKCGHENLH	ZNF676	66	Q8N7Q3
AARMLLHRCYKSIAN	POLR3C	431	Q9BUI4
RFYGEKPCHMDRLDR	PHLPP2	136	Q6ZVD8
CIDMGKELLARSHYA	SPTBN2	1966	O15020
DCMVKIYRHESLLGF	SLC25A45	41	Q8N413
LHILKNRMYGCDSVK	GTF2A1L	296	Q9UNN4
GRVHESVKRSNCYMV	RYR3	1376	Q15413
LTAMVDCRGLHKDYL	TTYH2	361	Q9BSA4
IAPCDEAYRKRMHQL	RASGEF1C	141	Q8N431
HMYCLREIVSRKGLA	TBC1D23	616	Q9NUY8
IISDGKMQLYRKHSC	ZNF607	86	Q96SK3
TKLVHMGRRDYDVLA	TENM4	2411	Q6N022
KRYCCRRMLLAHVDL	POLR2L	41	P62875
TMALIYAHKRCEIID	TTC21A	76	Q8NDW8
QSMDSKLSGRYRRHC	SMAP	86	O00193
LDKCSHRVLMYGSEL	TPH2	161	Q8IWU9
VHMRLHRGEKSYECY	ZBTB20	651	Q9HC78
KECGETFRLYRHMCL	ZNF404	246	Q494X3
IGMLRRYEECRHDNL	ZNF253	96	O75346
LRGMYEDLRQMCHKA	TRIM51G	226	A0A3B3IT33
KNICVDMLRDGYHKS	TTC29	66	Q8NA56
DRYHRKISICMSLLG	SLC46A2	101	Q9BY10
DTDSRHYKKRCQGRM	TRAPPC9	191	Q96Q05
YQVLDFRIRCGMKHG	GTF3C5	316	Q9Y5Q8
YVGMCLAASEKRLHA	TMEM129	71	A0AVI4
LDRCVSKYLDIHERM	TIMM10	51	P62072
HCSMRYGRLKASCQR	RHBDF2	146	Q6PJF5
CRGEYSILHRLKAAM	PLD2	711	O14939
MRRCDGLIDSLVHYV	PKP2	576	Q99959
RFMCHHAVRIRGKSY	TERT	811	O14746
SRHKVCIAQGYQRAM	SPOCK2	96	Q92563
ARAMARLGAVRSHYC	XXYLT1	11	Q8NBI6