Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionantigen binding

IGHV2-26 HLA-DRB4 IGHV4-38-2 IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-30-4 IGHV4-28

2.21e-051901228GO:0003823
GeneOntologyMolecularFunctionolfactory receptor activity

OR1M1 OR7G1 OR7A5 OR5G3 OR13C5 OR5H15 OR14C36 OR6V1 OR1Q1 OR1P1 OR5H1

6.83e-0543112211GO:0004984
GeneOntologyMolecularFunctiontranscription coregulator activity

NCOA3 ARL2BP PIAS2 ZXDA JMJD1C ZXDB HIPK3 PPARGC1A ZMIZ2 ATF7IP2 TRIM8 WDR77

1.71e-0456212212GO:0003712
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

NCOA3 PPARGC1A ASXL3

2.73e-04211223GO:0042975
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

NCOA3 PPARGC1A ZMIZ2 WDR77

5.29e-04611224GO:0030374
GeneOntologyMolecularFunctiontranscription coactivator activity

NCOA3 ARL2BP ZXDA ZXDB PPARGC1A ZMIZ2 TRIM8 WDR77

5.53e-043031228GO:0003713
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

NCOA3 ARL2BP COL19A1 ANK3 WNK1 PIAS2 ZXDA JMJD1C ZXDB HIPK3 KLHL3 PPARGC1A IGF2BP3 ZMIZ2 ATF7IP2 TRIM8 WDR77

6.89e-04116012217GO:0030674
GeneOntologyMolecularFunctionnuclear receptor binding

NCOA3 PIAS2 JMJD1C PPARGC1A IPO13 FOXP1

1.02e-031871226GO:0016922
GeneOntologyMolecularFunctionnuclear androgen receptor binding

NCOA3 PIAS2 FOXP1

1.06e-03331223GO:0050681
GeneOntologyCellularComponentimmunoglobulin complex

IGHV2-26 IGKV6D-21 IGHV4-38-2 IGHV4-61 IGHV4-59 IGKV6-21 IGHV4-31 IGHV4-30-4 IGHV4-28

7.03e-071661259GO:0019814
HumanPhenoPseudohypoaldosteronism

WNK1 KLHL3 NR3C2

8.17e-066393HP:0008242
DomainASH

ASPM HYDIN

3.63e-0521132IPR031549
DomainASH

ASPM HYDIN

3.63e-0521132PF15780
PathwayREACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

PIK3CD IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

1.36e-0553825MM15716
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR1M1 OR7G1 OR7A5 OR5G3 OR13C5 OR5H15 OR14C36 OR6V1 OR1Q1 OR1P1 OR5H1

2.82e-054178211M4072
PathwayREACTOME_CD22_MEDIATED_BCR_REGULATION

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

4.85e-0535824MM17219
PathwayREACTOME_CLASSICAL_ANTIBODY_MEDIATED_COMPLEMENT_ACTIVATION

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

7.49e-0539824MM17212
PathwayREACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

1.32e-0445824MM14912
PathwayREACTOME_FCGR_ACTIVATION

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

1.70e-0448824MM17214
PathwayREACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

2.70e-0454824MM14655
PathwayREACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

3.10e-0456824MM14815
PathwayREACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

3.55e-0458824MM14914
PathwayREACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

4.05e-0460824MM14872
PathwayREACTOME_FCERI_MEDIATED_MAPK_ACTIVATION

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

4.05e-0460824MM14913
Pubmed

Cloning, sequencing and expression of the rearranged MOPC 315 VH gene segment.

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

5.88e-09712742497341
Pubmed

Model-building studies of antigen-binding sites: the hapten-binding site of mopc-315.

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

5.88e-0971274268248
Pubmed

Amino acid sequence of the precursor region of MOPC-315 mouse immunoglobulin heavy chain.

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

5.88e-0971274414225
Pubmed

The idiotypic network and the internal image: possible regulation of a germ-line network by paucigene encoded Ab2 (anti-idiotypic) antibodies in the GAT system.

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

5.88e-09712743937730
Pubmed

The structure of the expressible VH gene from a hybridoma producing monoclonal antibodies against porcine transferrin.

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

5.88e-09712742587273
Pubmed

Amino-acid sequence of the variable region of the heavy (alpha) chain of a mouse myeloma protein with anti-hapten activity.

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

5.88e-09712744524622
Pubmed

A new germline VH36-60 gene is used in the neonatal primary and adult memory response to (T,G)-A--L.

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

5.88e-09712741683681
Pubmed

Structure and function of immunoglobulin genes and precursors.

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

3.50e-08101274428562
Pubmed

Interaction network of human early embryonic transcription factors.

NCOA3 SOBP PIAS2 ASXL3 ZMIZ2 TET1 KMT2A FOXP1 QSER1 RAI1

7.10e-073511271038297188
Pubmed

Early onset of somatic mutation in immunoglobulin VH genes during the primary immune response.

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

1.18e-062212742499654
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

BRIP1 SYNPO PIAS2 JMJD1C PAPOLG SCML2 ANLN KMT2A BOD1L1 QSER1 RAI1 ZNF292

2.53e-066081271236089195
Pubmed

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

JMJD1C BRCA2 TET1 QSER1

2.79e-0627127423395962
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NCOA3 PIAS2 BIRC6 JMJD1C BRCA2 ZMIZ2 TET1 BUB1B ATF7IP2 FOXP1

3.39e-064181271034709266
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

IFT140 FNDC3A SYNPO ANKRD27 TET1 IPO13 PDCD11 PLAGL2 AGAP7P CPSF2 RAI1

4.13e-065291271114621295
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR1M1 OR7G1 OR7A5 OR5G3 OR5H15 OR14C36 OR1Q1 OR1P1 OR5H1

4.73e-06340127911875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR1M1 OR7G1 OR7A5 OR5G3 OR5H15 OR14C36 OR1Q1 OR1P1 OR5H1

4.73e-06340127911802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR1M1 OR7G1 OR7A5 OR5G3 OR5H15 OR14C36 OR1Q1 OR1P1 OR5H1

5.08e-06343127932295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR1M1 OR7G1 OR7A5 OR5G3 OR5H15 OR14C36 OR1Q1 OR1P1 OR5H1

5.45e-06346127914611657
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

NCOA3 JMJD1C SCML2 ANLN KMT2A FOXP1 QSER1 RAI1

6.81e-06268127833640491
Pubmed

The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome.

NCOA3 JMJD1C PPARGC1A

7.68e-0611127336613751
Pubmed

Nonsyndromic Retinitis Pigmentosa Overview

SPATA7 IFT140 ARL2BP EYS USH2A

1.23e-0581127520301590
Pubmed

Genomic breakpoints and clinical features of MLL-TET1 rearrangement in acute leukemias.

TET1 KMT2A

1.32e-052127223100278
Pubmed

LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23).

TET1 KMT2A

1.32e-052127212124344
Pubmed

The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}.

NCOA3 PPARGC1A

1.32e-052127218957541
Pubmed

Mutation affecting the conserved acidic WNK1 motif causes inherited hyperkalemic hyperchloremic acidosis.

WNK1 KLHL3

1.32e-052127232790646
Pubmed

Potential role of BRCA2 in a mitotic checkpoint after phosphorylation by hBUBR1.

BRCA2 BUB1B

1.32e-052127210749118
Pubmed

A novel ADAMTS17 variant that causes Weill-Marchesani syndrome 4 alters fibrillin-1 and collagen type I deposition in the extracellular matrix.

FBN1 ADAMTS17

1.32e-052127231726086
Pubmed

Role of KLHL3 and dietary K+ in regulating KS-WNK1 expression.

WNK1 KLHL3

1.32e-052127233682442
Pubmed

Duplicated zinc finger protein genes on the proximal short arm of the human X chromosome: isolation, characterization and X-inactivation studies.

ZXDA ZXDB

1.32e-05212728268913
Pubmed

The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group.

TET1 KMT2A

1.32e-052127219144982
Pubmed

First description of the t(10;11)(q22;q23)/MLL-TET1 translocation in a T-cell lymphoblastic lymphoma, with subsequent lineage switch to acute myelomonocytic myeloid leukemia.

TET1 KMT2A

1.32e-052127224323992
Pubmed

The role of germline alterations in the DNA damage response genes BRIP1 and BRCA2 in melanoma susceptibility.

BRIP1 BRCA2

1.32e-052127227074266
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

BRIP1 FNDC3A WNK1 BIRC6 JMJD1C PAPOLG SCML2 ANLN BOD1L1 QSER1 CPSF2 AGTPBP1

1.66e-057331271234672954
Pubmed

Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study.

BRIP1 HUS1 PPARGC1A CLCA2 BRCA2

1.95e-0589127518950845
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

NCOA3 SOBP JMJD1C BRCA2 ZMIZ2 TRIM8

2.11e-05152127638360978
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

JMJD1C ATP2C1 WDR11 BOD1L1 CPSF2 HEATR5B

2.19e-05153127610718198
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PDE4D ANK3 SOBP SYNPO JMJD1C C2CD2 SGK2 HIPK3 ATP2C1 WDR11 ZNF827 RIN2 FOXP1 BOD1L1 ANKRD12 QSER1 RAI1

3.09e-0514891271728611215
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ANK3 JMJD1C SCML2 ANLN TET1 BUB1B PDCD11 KMT2A BOD1L1 QSER1

3.56e-055491271038280479
Pubmed

Circular RNA FOXP1 promotes tumor progression and Warburg effect in gallbladder cancer by regulating PKLR expression.

IGF2BP3 WDR11 ANLN FOXP1 HYDIN

3.76e-05102127531623628
Pubmed

CircRNA circHIPK3 serves as a prognostic marker to promote glioma progression by regulating miR-654/IGF2BP3 signaling.

HIPK3 IGF2BP3

3.96e-053127230057315
Pubmed

Impaired phosphorylation and mis-localization of Bub1 and BubR1 are responsible for the defective mitotic checkpoint function in Brca2-mutant thymic lymphomas.

BRCA2 BUB1B

3.96e-053127214646599
Pubmed

WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4.

WNK1 KLHL3

3.96e-053127229904119
Pubmed

Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice.

WNK1 KLHL3

3.96e-053127224821705
Pubmed

TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23).

TET1 KMT2A

3.96e-053127212646957
Pubmed

Polyglutamine repeat length in the AIB1 gene modifies breast cancer susceptibility in BRCA1 carriers.

NCOA3 BRCA2

3.96e-053127214648706
Pubmed

Breast cancer risk in BRCA1 and BRCA2 mutation carriers and polyglutamine repeat length in the AIB1 gene.

NCOA3 BRCA2

3.96e-053127215900600
Pubmed

Fibrillin-1, induced by Aurora-A but inhibited by BRCA2, promotes ovarian cancer metastasis.

FBN1 BRCA2

3.96e-053127225749384
Pubmed

Polymorphic repeat length in the AIB1 gene and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a meta-analysis of observational studies.

NCOA3 BRCA2

3.96e-053127223483928
Pubmed

The AIB1 gene polyglutamine repeat length polymorphism and the risk of breast cancer development.

NCOA3 BRCA2

3.96e-053127220422428
Pubmed

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

NCOA3 JMJD1C PPARGC1A

6.03e-0521127319596656
Pubmed

Negative modulation of androgen receptor transcriptional activity by Daxx.

NCOA3 PIAS2 PPARGC1A

6.96e-0522127315572661
Pubmed

Differences between germ-line and rearranged immunoglobulin V kappa coding sequences suggest a localized mutation mechanism.

IGKV6D-21 IGKV6-21

7.90e-05412726264318
Pubmed

FANCD2, FANCJ and BRCA2 cooperate to promote replication fork recovery independently of the Fanconi Anemia core complex.

BRIP1 BRCA2

7.90e-054127225659033
Pubmed

Chromosomal organization of the human VH4 gene family. Location of individual gene segments.

IGHV4-59 IGHV4-31

7.90e-05412728454861
Pubmed

Characterization of a novel small molecule subtype specific estrogen-related receptor alpha antagonist in MCF-7 breast cancer cells.

NCOA3 PPARGC1A

7.90e-054127219462000
Pubmed

Pseudohypoaldosteronism Type II

WNK1 KLHL3

7.90e-054127222073419
Pubmed

Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4.

WNK1 KLHL3

7.90e-054127223576762
Pubmed

Defects of FA/BRCA pathway in lymphoma cell lines.

BRIP1 BRCA2

7.90e-054127219011769
Pubmed

Weill-Marchesani Syndrome

FBN1 ADAMTS17

7.90e-054127220301293
Pubmed

Identification of MLL-fusion/MYC⊣miR-26⊣TET1 signaling circuit in MLL-rearranged leukemia.

TET1 KMT2A

7.90e-054127226791235
Pubmed

Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

OR1M1 OR7A5 OR1Q1

9.10e-052412739119360
Pubmed

Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures.

OR7A5 OR14C36 OR5H1

1.30e-0427127332061665
Pubmed

Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease.

ANK3 TET1

1.31e-045127218163421
Pubmed

Structural and biochemical characterization of the KLHL3-WNK kinase interaction important in blood pressure regulation.

WNK1 KLHL3

1.31e-045127224641320
Pubmed

Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1.

BRCA2 BUB1B

1.31e-045127232286328
Pubmed

The novel PIAS-like protein hZimp10 enhances Smad transcriptional activity.

PIAS2 ZMIZ2

1.31e-045127216777850
Pubmed

Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor.

NCOA3 PPARGC1A

1.31e-045127218798693
Pubmed

Activation of BRCA1/BRCA2-associated helicase BACH1 is required for timely progression through S phase.

BRIP1 BRCA2

1.31e-045127217664283
Pubmed

Recruitment of fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication.

BRIP1 BRCA2

1.31e-045127219748364
Pubmed

Doubling the size of the glucocorticoid receptor ligand binding pocket by deacylcortivazol.

NCOA3 PPARGC1A

1.31e-045127218160712
Pubmed

The human olfactory receptor gene family.

OR1M1 OR7G1 OR7A5 OR5G3 OR13C5 OR14C36 OR6V1 OR1Q1 OR1P1

1.74e-04541127914983052
Pubmed

IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes.

IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-28

1.87e-0477127415608191
Pubmed

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.

EMILIN3 SYNPO BIRC6 SGK2 WDR11 ASXL3 PDCD11 RAI1

1.93e-04431127833660365
Pubmed

A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma-coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro.

NCOA3 PPARGC1A

1.97e-046127216373399
Pubmed

PALB2 is an integral component of the BRCA complex required for homologous recombination repair.

BRIP1 BRCA2

1.97e-046127219369211
Pubmed

Repression of the Transactivating Capacity of the Oncoprotein PLAG1 by SUMOylation.

PIAS2 PLAGL2

1.97e-046127215208321
Pubmed

A massively parallel pipeline to clone DNA variants and examine molecular phenotypes of human disease mutations.

ARL2BP BRIP1 KLHL3 BUB1B

2.06e-0479127425502805
Pubmed

HDAC2/3 binding and deacetylation of BubR1 initiates spindle assembly checkpoint silencing.

BRCA2 BUB1B

2.75e-047127228985013
Pubmed

Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individuals.

BRIP1 BRCA2

2.75e-047127221356067
Pubmed

FBXL10 promotes ERRα protein stability and proliferation of breast cancer cells by enhancing the mono-ubiquitylation of ERRα.

NCOA3 PPARGC1A

2.75e-047127233450359
Pubmed

Polymorphisms in DNA double-strand break repair genes and risk of breast cancer: two population-based studies in USA and Poland, and meta-analyses.

BRIP1 BRCA2

2.75e-047127216485136
Pubmed

Mettl14-mediated m6A modification ensures the cell-cycle progression of late-born retinal progenitor cells.

BRIP1 BRCA2 ZNF292

2.86e-0435127337269288
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TANC2 EXPH5 KLC2 WNK1 ANKRD27 ANLN TET1 BUB1B KMT2A BOD1L1 NR3C2

3.30e-048611271136931259
Pubmed

The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus.

IGHV2-26 IGHV4-61 IGHV4-59 IGHV4-28

3.55e-049112749841928
Pubmed

Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway.

FBN1 ADAMTS17

3.65e-048127231201465
Pubmed

EMILIN proteins are novel extracellular constituents of the dentin-pulp complex.

EMILIN3 FBN1

3.65e-048127232948785
Pubmed

Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif.

PIAS2 HIPK3

3.65e-048127210961991
Pubmed

The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction.

WNK1 KLHL3

3.65e-048127223387299
Pubmed

Different noses for different people.

OR5G3 OR1P1

3.65e-048127212730696
Pubmed

KLHL2 interacts with and ubiquitinates WNK kinases.

WNK1 KLHL3

3.65e-048127223838290
Pubmed

5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex.

TET1 WDR77

3.65e-048127225284789
Pubmed

Requirement of heterogeneous nuclear ribonucleoprotein C for BRCA gene expression and homologous recombination.

BRIP1 BRCA2

3.65e-048127223585894
Pubmed

Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor γ (PPARγ) ligand with a unique binding mode and effective glucose-lowering activity in a mouse model of diabetes.

NCOA3 PPARGC1A

3.65e-048127223178929
Pubmed

Molecular basis of human Usher syndrome: deciphering the meshes of the Usher protein network provides insights into the pathomechanisms of the Usher disease.

SOBP USH2A

3.65e-048127216545802
Pubmed

The Penta-EF-Hand ALG-2 Protein Interacts with the Cytosolic Domain of the SOCE Regulator SARAF and Interferes with Ubiquitination.

FNDC3A MIA2

3.65e-048127232878247
Pubmed

Identification of potential regulatory motifs in odorant receptor genes by analysis of promoter sequences.

OR1P1 OR5H1

3.65e-048127216902085
Pubmed

Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia.

WNK1 KLHL3

3.65e-048127226286618
Pubmed

A human MAP kinase interactome.

IFT140 ARL2BP ANK3 EXPH5 SYNPO WNK1 PIAS2 HIPK3

4.31e-04486127820936779
Pubmed

Functional and mutational landscapes of BRCA1 for homology-directed repair and therapy resistance.

BRIP1 BRCA2

4.68e-049127228398198
Pubmed

Conserved overlapping gene arrangement, restricted expression, and biochemical activities of DNA polymerase ν (POLN).

BRIP1 BRCA2

4.68e-049127226269593
Cytoband14q32.33

IGHV2-26 IGHV4-38-2 IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-30-4 IGHV4-28

3.66e-06228127714q32.33
Cytoband20q12

NCOA3 EMILIN3 KCNS1

4.01e-0524127320q12
GeneFamilyImmunoglobulin heavy locus at 14q32.33

IGHV2-26 IGHV4-38-2 IGHV4-61 IGHV4-59 IGHV4-31 IGHV4-30-4 IGHV4-28

3.29e-05187877349
GeneFamilyZinc fingers MIZ-type

PIAS2 ZMIZ2

4.73e-04787285
GeneFamilyOlfactory receptors, family 1

OR1M1 OR1Q1 OR1P1

9.35e-0440873147
GeneFamilyVPS9 domain containing

ANKRD27 RIN2

1.00e-0310872928
GeneFamilyAnkyrin repeat domain containing

TANC2 ANK3 ANKRD27 ANKRD34B ANKRD12 AGAP7P

1.11e-03242876403
GeneFamilyZinc fingers CXXC-type

TET1 KMT2A

1.46e-0312872136
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

WNK1 PDCD11 UTY

1.90e-0351873870
GeneFamilyRing finger proteins|Fanconi anemia complementation groups|Protein phosphatase 1 regulatory subunits|BRCA1 A complex|BRCA1 B complex|BRCA1 C complex

BRIP1 BRCA2

4.11e-0320872548
GeneFamilyPHD finger proteins|Lysine demethylases

JMJD1C UTY

5.90e-0324872485
CoexpressionLAKE_ADULT_KIDNEY_C15_CONNECTING_TUBULE

TANC2 PDE4D ANK3 FNDC3A WNK1 PPARGC1A NR3C2

1.28e-051711187M39234
CoexpressionLAKE_ADULT_KIDNEY_C17_COLLECTING_SYSTEM_PCS_STRESSED_DISSOC_SUBSET

TANC2 PDE4D ANK3 FNDC3A JMJD1C PPARGC1A NR3C2 ZNF292

1.35e-052401188M39236
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#3

TANC2 PDE4D SOBP EMILIN3 SYNPO FBN1 BRCA2 ZNF827 FMN1 ASXL3 ADAMTS17 BOD1L1 NR3C2 ANKRD12 QSER1

2.62e-0583411015Facebase_RNAseq_e10.5_Mandibular Arch_2500_K3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000

TANC2 ANK3 EMILIN3 WNK1 BIRC6 HIPK3 ASXL3 FOXP1 PLXNA2 AGTPBP1

3.20e-0538511010gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#3

TANC2 PDE4D ANK3 SOBP EMILIN3 SYNPO FBN1 ZNF827 NR3C2 ANKRD12 UTY PLXNA2

3.81e-0556711012Facebase_RNAseq_e10.5_Olfactory Pit_2500_K3
CoexpressionAtlasFetal Liver, SC.STSL.FL, IgM- CD24- CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Fetal Liver, avg-2

BRIP1 SLC43A3 IGF2BP3 OIT3 BRCA2 ANLN TET1 BUB1B ASPM QSER1

5.44e-0541011010GSM791122_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3

SPATA7 PDE4D SLC43A3 WNK1 BRCA2 TET1 BOD1L1 QSER1 HEATR5B ZNF292

8.39e-0543211010Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

SPATA7 FNDC3A WNK1 PIAS2 PPARGC1A BRCA2 TET1 BOD1L1 QSER1 HEATR5B IQCK ZNF292

1.03e-0462911012Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000

ANK3 HUS1 EMILIN3 HIPK3 PPARGC1A ASPM FOXP1 AGTPBP1 ZNF292

1.30e-043691109DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#5_top-relative-expression-ranked_1000

TANC2 PIAS2 ZXDB PPARGC1A IGF2BP3 SCML2 FOXP1 CPSF2 UTY ZNF292

2.41e-0449211010gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k5
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000

NCOA3 EMILIN3 FNDC3A SNX16 BIRC6 JMJD1C SCML2 ASXL3 TET1 ASPM ANKRD12 UTY PLXNA2

2.58e-0480111013gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000

ANK3 HUS1 EMILIN3 HIPK3 PPARGC1A PDLIM3 CLCA2 ASPM FOXP1 CPSF2 PLXNA2 AGTPBP1 ZNF292

2.74e-0480611013DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000

BRIP1 SCML2 PDLIM3 BRCA2 ANLN PIK3CD FMN1 TET1 BUB1B ATF7IP2 PDCD11 ANKRD12 WDR77

2.88e-0481011013gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_1000

TANC2 NCOA3 PDE4D COL19A1 EMILIN3 BIRC6 HIPK3 LYVE1 SCML2 CLCA2 ASPM FOXP1 AGTPBP1

2.91e-0481111013gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000
CoexpressionAtlasB cells, proB.CLP.FL, CD19- IgM- CD43+ CD24intermediate CD45R- AA4.1+ CD, Fetal Liver, avg-1

BRIP1 SLC43A3 IGF2BP3 BRCA2 ANLN TET1 BUB1B ASPM QSER1

3.28e-044181109GSM538350_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#5

EMILIN3 SYNPO BRCA2 FMN1 ASXL3 ADAMTS17 BOD1L1 QSER1

3.31e-043311108Facebase_RNAseq_e10.5_Mandibular Arch_1000_K5
CoexpressionAtlasB cells, proB.CLP.FL, CD19- IgM- CD43+ CD24intermediate AA4.1+ CD45R- CD, Fetal Liver, avg-2

BRIP1 SLC43A3 IGF2BP3 BRCA2 ANLN TET1 BUB1B ASPM QSER1

3.34e-044191109GSM538348_500
CoexpressionAtlasB cells, proB.FrA.FL, CD19- IgM- CD43+ CD24intermediate AA4.1+ CD45R+ CD, Fetal Liver, avg-2

BRIP1 SLC43A3 IGF2BP3 BRCA2 ANLN TET1 BUB1B ASPM QSER1

3.51e-044221109GSM538355_500
CoexpressionAtlasalpha beta T cells, T.8Nve.PP, TCRb+ CD8+ CD44low CD62L high, Peyer's Patch, avg-1

WNK1 BIRC6 PAPOLG ZNF827 TET1 KMT2A FOXP1 ZNF292

3.66e-043361108GSM538413_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000

TANC2 PDE4D COL19A1 PIAS2 ZXDB PPARGC1A IGF2BP3 SCML2 CLCA2 FOXP1 CPSF2 UTY ZNF292

3.89e-0483611013gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNPO ZXDB LYVE1 PDLIM3 ASPM GLIPR1L1 DDX28

4.42e-081191247c3f1223356e7f245a460ea5568a223e34e458dc1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 SLC43A3 BRCA2 ANLN BUB1B ASPM FBXO43

2.95e-0715712471ccb07a38d3fb606ee5fbc0437655f49baaaa62c
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

ANK3 KCNS1 FOXP1 NR3C2 ANKRD12 GOLGA8A UTY

3.64e-071621247b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 SCML2 BRCA2 ANLN BUB1B ASPM FBXO43

4.47e-071671247bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 FBN1 BRCA2 ANLN BUB1B ASPM FBXO43

5.25e-071711247b0373ed8283ee1792b6a490bff93906546978593
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 FBN1 BRCA2 ANLN BUB1B ASPM FBXO43

5.25e-071711247b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 BRCA2 ANLN PIK3CD BUB1B ASPM FBXO43

5.25e-07171124755c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGK2 SPATC1 PPARGC1A FMN1 ASXL3 FAM222A ADAMTS17

6.87e-071781247dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PPARGC1A FICD BRCA2 ANLN BUB1B ASPM FBXO43

7.14e-071791247021d782134126c6f7dce6b6ea50cc54bdaa39987
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGK2 SPATC1 PPARGC1A FMN1 ASXL3 FAM222A ADAMTS17

7.14e-071791247d0fa700648db8ce76a8aa689879a25048299fa40
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D EXPH5 WNK1 KLHL3 PPARGC1A FMN1 NR3C2

7.14e-071791247666072c0e8448dbaec1683d18368ec2502453f90
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGK2 SPATC1 PPARGC1A FMN1 ASXL3 FAM222A ADAMTS17

7.14e-0717912472e49b215b71438400aebb483f2c2c08d5e956961
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 WNK1 KLHL3 PPARGC1A FMN1 ADAMTS17 NR3C2

7.98e-0718212475f513bbb7125956eb528e3120de3fd776770a7c3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 FBN1 BRCA2 ANLN BUB1B ASPM FBXO43

9.57e-071871247e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 FBN1 BRCA2 ANLN BUB1B ASPM FBXO43

9.57e-071871247cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 BRCA2 ANLN PIK3CD BUB1B ASPM FBXO43

9.57e-07187124773931a5ea73799095daff100b5f18853c57c74dc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 WNK1 KLHL3 PPARGC1A FMN1 ADAMTS17 NR3C2

9.91e-071881247bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 WNK1 KLHL3 PPARGC1A FMN1 ADAMTS17 NR3C2

9.91e-071881247eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 WNK1 KLHL3 PPARGC1A FMN1 ADAMTS17 NR3C2

1.03e-061891247977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 WNK1 KLHL3 PPARGC1A FMN1 ADAMTS17 NR3C2

1.03e-061891247975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 WNK1 KLHL3 PPARGC1A FMN1 ADAMTS17 NR3C2

1.03e-0618912477eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PDE4D KLHL3 PPARGC1A FMN1 ASXL3 NR3C2

1.06e-0619012474836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 WNK1 KLHL3 PPARGC1A FMN1 ADAMTS17 NR3C2

1.06e-061901247e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

LYVE1 BRCA2 ANLN PIK3CD FMN1 BUB1B ASPM

1.14e-061921247a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

ASPM PDCD11 KMT2A BOD1L1 ANKRD12 GOLGA8A ZNF292

1.14e-0619212479cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

ANK3 JMJD1C KMT2A FOXP1 ANKRD12 GOLGA8A UTY

1.14e-06192124747646d7e4990be85072987f92bf18d52f8da752e
ToppCellRV-08._Macrophage|RV / Chamber and Cluster_Paper

LYVE1 BRCA2 ANLN PIK3CD FMN1 BUB1B ASPM

1.18e-06193124712bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCellHealthy/Control-T/NK_proliferative|Healthy/Control / Disease group and Cell class

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43 HYDIN

1.27e-061951247957458fdc39723f4a31bd7fd3ce32891aa3fd462
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 EXPH5 WNK1 KLHL3 PPARGC1A FMN1 ADAMTS17

1.27e-061951247a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCellmLN-B_cell-B_cell_cycling|mLN / Region, Cell class and subclass

ANLN BUB1B ASPM IGHV4-59 IGKV6-21 IGHV4-31 IGHV4-28

1.35e-061971247806dddcca85c82bd642008d930c8db16b613d88e
ToppCellmLN-(2)_B_cell-(24)_B_cell_cycling|mLN / shred on region, Cell_type, and subtype

ANLN BUB1B ASPM IGHV4-59 IGKV6-21 IGHV4-31 IGHV4-28

1.35e-06197124770fff2d6723f259e18e7a21d22dc46d71f0759ce
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BIRC6 JMJD1C KMT2A BOD1L1 ANKRD12 GOLGA8A ZNF292

1.50e-06200124712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BRIP1 ANKRD34B BRCA2 ANLN BUB1B ASPM FBXO43

1.50e-062001247af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

WNK1 KLHL3 FMN1 FAM222A ADAMTS17 USH2A

2.69e-0614012465e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCellDividing_Macrophages-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

SRRM5 SPATC1 ANLN BUB1B ASPM FBXO43

3.71e-06148124666b51aa6690bf8fbc90fa5a6f86191703e2d5046
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

ANK3 JMJD1C FOXP1 ANKRD12 GOLGA8A UTY

5.03e-0615612461545169694f686d28648a68b552c2ae606599d66
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 WNK1 SGK2 KLHL3 FMN1 GOLGA8A

5.03e-0615612464d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCML2 BRCA2 ANLN BUB1B ASPM FBXO43

6.94e-061651246eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

7.18e-0616612462642544070564debe2deb2938d2c33997bf5ef02
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

7.43e-06167124650c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

7.69e-061681246d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

7.95e-061691246b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

7.95e-0616912460bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 SLC43A3 ANLN BUB1B ASPM FBXO43

8.23e-06170124621bfe070e63722672176052b386167ea4c3dc4e5
ToppCellmetastatic_Brain-B_lymphocytes-Plasma_cells|metastatic_Brain / Location, Cell class and cell subclass

IGKV6D-21 IGHV4-61 IGHV4-59 IGKV6-21 IGHV4-31 IGHV4-28

8.23e-06170124653634da9e9c72f6400639954c286c6e38ea5a188
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 EXPH5 WNK1 KLHL3 PPARGC1A FMN1

9.09e-0617312460c74bdb40e635d906fd180412c23bf7fed61621e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WNK1 KLHL3 PPARGC1A FMN1 ADAMTS17 OR5H1

9.09e-0617312464bc6d93716f093b460c8b047199db8cab5fea720
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

9.39e-06174124684da9faff088d05233183b425385beb054c92d1b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 ANLN PIK3CD BUB1B ASPM FBXO43

9.39e-0617412467b318796728001c17b4043d2b033330c7be40c78
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

9.39e-061741246dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCellRSV-Healthy-2|Healthy / Virus stimulation, Condition and Cluster

SOBP ANLN FMN1 TET1 ASPM WDR77

9.71e-061751246c47440c0b0513e67fe13b85f10dd8a8d42d0e9a3
ToppCellRSV-Healthy-2|RSV / Virus stimulation, Condition and Cluster

SOBP ANLN FMN1 TET1 ASPM WDR77

9.71e-0617512460e97189585b7afaf3bd622c3ef10c86412393829
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

9.71e-061751246876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

NCOA3 SLC43A3 ANLN PDCD11 UTY SLC9A6

1.00e-0517612463de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

NCOA3 SLC43A3 ANLN PDCD11 UTY SLC9A6

1.04e-05177124682fdd6185b368f54f03de389427cbe3071d21a99
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.04e-05177124673ba0f0b4b33f10e9f036d6d9befa48a1258e682
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SYNPO ZXDB LYVE1 PDLIM3 GLIPR1L1 DDX28

1.14e-051801246baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SGK2 SPATC1 PPARGC1A FMN1 FAM222A ADAMTS17

1.14e-0518012469e09b3dfe344b5d50520711513d389865d73a861
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.14e-051801246401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SYNPO ZXDB LYVE1 PDLIM3 GLIPR1L1 DDX28

1.14e-0518012462d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SYNPO ZXDB LYVE1 PDLIM3 GLIPR1L1 DDX28

1.14e-0518012460f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCellBAL-Mild-Lymphocyte-B|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

COL19A1 IGHV4-61 IGHV4-59 IGKV6-21 IGHV4-31 IGHV4-28

1.18e-051811246700adfb41e4e377530f0dd31be89e12f109f3469
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WNK1 KLHL3 PPARGC1A FMN1 ADAMTS17 OR5H1

1.18e-051811246e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

ANK3 JMJD1C FOXP1 ANKRD12 GOLGA8A UTY

1.18e-051811246f2315414e714ac86211546a935660c4be6e85f1b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 WNK1 PIAS2 KLHL3 PPARGC1A FMN1

1.25e-0518312462f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5|TCGA-Liver / Sample_Type by Project: Shred V9

IGF2BP3 BRCA2 ANLN BUB1B ASPM FBXO43

1.25e-051831246f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCellMild-Lymphoid-B|Mild / Condition, Lineage, Cell class and cell subclass

COL19A1 IGHV4-61 IGHV4-59 IGKV6-21 IGHV4-31 IGHV4-28

1.25e-0518312469b64d2d143525e6f48a191facfd101462ff36324
ToppCellMild-Lymphoid-B-|Mild / Condition, Lineage, Cell class and cell subclass

COL19A1 IGHV4-61 IGHV4-59 IGKV6-21 IGHV4-31 IGHV4-28

1.25e-051831246b5740f05a4dcdbbf24f7bf7a3f57ac01a5e75f60
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 WNK1 KLHL3 PPARGC1A FMN1 NR3C2

1.25e-0518312462e831a4d99c6f983793df71c0994124c943c6da9
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

COL19A1 IGHV4-61 IGHV4-59 IGKV6-21 IGHV4-31 IGHV4-28

1.29e-0518412463f8a359e40bebe58545f708682e5e5d1b70cf5cb
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

COL19A1 IGHV4-61 IGHV4-59 IGKV6-21 IGHV4-31 IGHV4-28

1.29e-05184124664bede8db709fd32f40c03265b96f0b12155bb8a
ToppCellBAL-Mild-Lymphocyte-B-B_cell|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

COL19A1 IGHV4-61 IGHV4-59 IGKV6-21 IGHV4-31 IGHV4-28

1.33e-051851246609080adb2cfb105bb7b8efb617553833299f371
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

BRIP1 IGF2BP3 BRCA2 ANLN BUB1B ASPM

1.33e-0518512469766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.33e-05185124630e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D WNK1 KLHL3 PPARGC1A FMN1 NR3C2

1.37e-051861246d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SGK2 SPATC1 PPARGC1A FMN1 FAM222A ADAMTS17

1.41e-05187124685e58a312fc325e4063a2d250666b99b8f99beb6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SGK2 SPATC1 PPARGC1A FMN1 FAM222A ADAMTS17

1.41e-05187124652b5b38bef3cc06487cf42c6fb22fb33f0c7ce2b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.41e-0518712469351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.41e-051871246057569c9437219ecc396aa6e673b1178a2273837
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WNK1 KLHL3 PPARGC1A FMN1 ADAMTS17 NR3C2

1.50e-051891246f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellrenal_cortex_nuclei-Adult_normal_reference|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D ANK3 FNDC3A BOD1L1 UTY PLXNA2

1.50e-051891246a48df46274d51e84ffb40264646de7346104efb9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.55e-05190124631de1727822e9818652946dfb962daee77ffad68
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WNK1 KLHL3 PPARGC1A FMN1 ADAMTS17 NR3C2

1.55e-051901246b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BRIP1 BRCA2 ANLN BUB1B ASPM PLXNA2

1.55e-051901246e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCellEndothelial-D_(cycle)|World / shred on cell class and cell subclass (v4)

BRIP1 SLC43A3 LYVE1 ANLN BUB1B ASPM

1.59e-05191124649a4d8f181558e3be9527a8ff9a178f3bb01323c
ToppCellCOVID-19-kidney-Proliferating_T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.59e-051911246bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCellCOVID-19-kidney-CNT|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE4D ANK3 SGK2 PPARGC1A ANKRD34B NR3C2

1.64e-051921246760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TANC2 PDE4D BIRC6 JMJD1C FMN1 FOXP1

1.69e-051931246779276e775cb2492e8dd36436295a536084a6415
ToppCellControl-Lymphoid-Proliferating_CD4_T_cells|Control / Condition, Lineage and Cell class

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.69e-05193124633d409d6ed1c606337248587ad997ac5f67f081d
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.74e-051941246f39a471293ecc5c5967b00e772b8f48ebc9affbe
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.74e-051941246f9070035553bc68106a9e0bdf4b507715a138aba
ToppCellControl-Lymphoid_T/NK-T/NK_proliferative|Control / Disease group, lineage and cell class

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.74e-0519412469bbb124001fba7450f4639f47f9b720a483e7242
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.74e-051941246a75ecd0b0a928d4646602f7d16a645f6b3df3af5
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.74e-05194124617744fd6645cf5a447a01a83f07e8d305c2bcd9c
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BRIP1 SLC43A3 LYVE1 ANLN BUB1B ASPM

1.74e-0519412463a49c7c86036e09a8cd0114988380d04ad1a26fb
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.74e-051941246e14f66f7584909621b776292fbd52808273fd2ee
ToppCellCOVID-19-kidney-Proliferating_T_cell|kidney / Disease (COVID-19 only), tissue and cell type

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.79e-0519512467e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D EXPH5 WNK1 KLHL3 PPARGC1A ANKRD34B

1.79e-0519512463f517c6fc372bdcaf45b3af373414f13cbebd4ba
ToppCellCOVID-19-lung-Proliferative_fibroblast|lung / Disease (COVID-19 only), tissue and cell type

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.85e-0519612462ce8a787f2731faa913d20342d73041d59468f27
ToppCellCOVID-19-lung-Proliferative_fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

BRIP1 BRCA2 ANLN BUB1B ASPM FBXO43

1.85e-051961246ca91d5e325875e7444809b80fcbd491d8899ea36
Diseasepseudohypoaldosteronism (is_implicated_in)

WNK1 KLHL3 NR3C2

2.56e-0681073DOID:4479 (is_implicated_in)
DiseasePseudohypoaldosteronism, Type I

WNK1 KLHL3 NR3C2

5.46e-06101073C0268436
DiseasePseudohypoaldosteronism

WNK1 KLHL3 NR3C2

5.46e-06101073C0033805
DiseaseHyperpotassemia and Hypertension, Familial

WNK1 KLHL3 NR3C2

5.46e-06101073C2713447
DiseasePseudohypoaldosteronism, Type I, Autosomal Recessive

WNK1 KLHL3 NR3C2

5.46e-06101073C1449843
DiseasePseudohypoaldosteronism, Type II

WNK1 KLHL3 NR3C2

5.46e-06101073C1449844
DiseasePseudohypoaldosteronism, Type I, Autosomal Dominant

WNK1 KLHL3 NR3C2

5.46e-06101073C1449842
Diseaseprogression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian serous carcinoma

PDE4D EYS IGF2BP3 ADAMTS17

1.65e-05421074EFO_0004920, EFO_1001516, GO_0097328, MONDO_0009354
DiseaseNeurodevelopmental Disorders

TANC2 ASXL3 KMT2A FOXP1 ZNF292

2.30e-05931075C1535926
DiseaseWeill-Marchesani syndrome (implicated_via_orthology)

FBN1 ADAMTS17

3.90e-0531072DOID:0050475 (implicated_via_orthology)
DiseaseRetinitis Pigmentosa

SPATA7 IFT140 ARL2BP EYS USH2A

3.95e-051041075C0035334
DiseasePseudohypoaldosteronism type 2A

WNK1 KLHL3

7.78e-0541072cv:C1840389
DiseasePseudohypoaldosteronism, type 2

WNK1 KLHL3

7.78e-0541072cv:C1449844
DiseaseWeill-Marchesani syndrome

FBN1 ADAMTS17

7.78e-0541072cv:C0265313
DiseaseWeill-Marchesani syndrome (is_implicated_in)

FBN1 ADAMTS17

7.78e-0541072DOID:0050475 (is_implicated_in)
Diseaseretinitis pigmentosa (implicated_via_orthology)

EYS USH2A AGTPBP1

1.27e-04271073DOID:10584 (implicated_via_orthology)
Diseasepseudohypoaldosteronism (implicated_via_orthology)

WNK1 KLHL3

1.94e-0461072DOID:4479 (implicated_via_orthology)
DiseaseAutism Spectrum Disorders

TET1 FOXP1 USH2A RAI1

2.64e-04851074C1510586
Diseasecognitive function measurement, self reported educational attainment

TANC2 PDE4D BIRC6 JMJD1C ZMIZ2 FOXP1 AFG1L

3.20e-043551077EFO_0004784, EFO_0008354
Diseaseheart disease (implicated_via_orthology)

PPARGC1A FBN1 PIK3CD

3.57e-04381073DOID:114 (implicated_via_orthology)
Diseaseprostate carcinoma

TANC2 IFT140 EXPH5 WDR11 ZNF827 ANLN FMN1 TRIM8 FOXP1 QSER1 AGAP7P

3.97e-0489110711EFO_0001663
DiseaseLiver carcinoma

LYVE1 IGF2BP3 OIT3 ANLN BUB1B ASPM KMT2A SLC25A47

5.30e-045071078C2239176
Diseasecoffee consumption measurement

BIRC6 PPARGC1A EYS HYDIN RAI1

5.40e-041821075EFO_0006781
Diseasecerebral palsy (implicated_via_orthology)

ADD2 AGAP7P

5.75e-04101072DOID:1969 (implicated_via_orthology)
Diseasecholesterol to total lipids in large VLDL percentage

TDRD15 JMJD1C MYRF

5.89e-04451073EFO_0022236
Diseaseserum IgG glycosylation measurement

CWF19L2 COL19A1 EYS IGF2BP3 FMN1 ADAMTS17 FOXP1 USH2A

6.49e-045231078EFO_0005193
Diseasefibrinogen measurement

DCHS2 JMJD1C WDR11 NR3C2

6.79e-041091074EFO_0004623
Diseaseamino acid measurement

TANC2 BRIP1 PDE4D SYNPO FMN1 ATF7IP2 OR1P1 NR3C2 PLXNA2

8.22e-046781079EFO_0005134
Diseaseomega-3 polyunsaturated fatty acid measurement

TDRD15 JMJD1C ZMIZ2 MYRF

9.13e-041181074EFO_0010119
Diseasetriglycerides to total lipids in very large VLDL percentage

TDRD15 JMJD1C MYRF

9.52e-04531073EFO_0022340
Diseasecholesteryl esters to total lipids in very large VLDL percentage

TDRD15 JMJD1C MYRF

9.52e-04531073EFO_0022258
Diseasecholesterol to total lipids in very large VLDL percentage

TDRD15 JMJD1C MYRF

1.01e-03541073EFO_0022244
Diseaseparathyroid hormone measurement

PDE4D FMN1 RIN2

1.06e-03551073EFO_0004752
Diseaseleukemia

NCOA3 BRIP1 KMT2A

1.06e-03551073C0023418
Diseaseneuroticism measurement, cognitive function measurement

BIRC6 JMJD1C ASXL3 ZMIZ2 FOXP1 NR3C2 RAI1 AFG1L

1.08e-035661078EFO_0007660, EFO_0008354
Diseasecholesteryl esters to total lipids in large VLDL percentage

TDRD15 JMJD1C MYRF

1.12e-03561073EFO_0022250
DiseaseFanconi anemia

BRIP1 BRCA2

1.15e-03141072cv:C0015625
DiseaseHereditary Breast and Ovarian Cancer Syndrome

BRIP1 BRCA2

1.15e-03141072C0677776
Diseasefree cholesterol to total lipids in medium VLDL percentage

TDRD15 JMJD1C MYRF

1.18e-03571073EFO_0022284
Diseasedocosahexaenoic acid measurement

TDRD15 JMJD1C ZMIZ2 MYRF

1.20e-031271074EFO_0007761
Diseasefree cholesterol to total lipids in very large VLDL percentage

TDRD15 JMJD1C MYRF

1.30e-03591073EFO_0022289
Diseasefourth ventricle volume measurement

CWF19L2 ADD2

1.51e-03161072EFO_0010303
Diseasetriglycerides to total lipids in medium VLDL percentage

TDRD15 JMJD1C MYRF

1.57e-03631073EFO_0022335
Diseasecholesterol to total lipids in medium VLDL percentage

TDRD15 JMJD1C MYRF

1.57e-03631073EFO_0022239
Diseasecholesteryl esters to total lipids in medium VLDL percentage

TDRD15 JMJD1C MYRF

1.64e-03641073EFO_0022253
Diseaserespiratory symptom change measurement, response to placebo

PPARGC1A ATF7IP2

1.71e-03171072EFO_0008344, EFO_0010068
DiseaseMicrocephaly

BUB1B SLC9A6 ZNF292

1.88e-03671073C0025958
DiseaseBone marrow hypocellularity

BRIP1 BRCA2

1.92e-03181072C1855710
DiseaseNonorganic psychosis

ANK3 SOBP TET1

2.04e-03691073C0349204
Diseasemigraine disorder, endometriosis

SNX16 EYS FOXP1

2.40e-03731073EFO_0001065, MONDO_0005277
Diseasepentachlorophenol measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022071
Diseaseparathion measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022070
Diseasepotassium chromate measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022072
Diseasemercuric chloride measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022068
Diseaseheptachlor epoxide measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022067
Diseasemethoxychlor measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022069
Disease4,6-dinitro-o-cresol measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022053
Disease2,4,5-trichlorophenol measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022052
Diseaseazinphos methyl measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022055
Diseasealdrin measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022054
Diseasedicofol measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022060
Diseasedisulfoton measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022062
Diseasedieldrin measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022061
Diseaseendrin measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022064
Diseaseendosulfan measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022063
Diseaseheptachlor measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022066
Diseaseethion measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022065
Diseasechlorpyrifos measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022057
Diseasecadmium chloride measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022056
Diseasediazinon measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022059
Diseasedibutyl phthalate measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0022058
Diseaseenvironmental exposure measurement

PDE4D EYS USH2A

2.40e-03731073EFO_0008360
DiseaseRetinitis pigmentosa

SPATA7 EYS USH2A

2.49e-03741073cv:C0035334
DiseaseDDT metabolite measurement

PDE4D EYS USH2A

2.49e-03741073EFO_0007886
DiseasePrecursor B-cell lymphoblastic leukemia

KMT2A FOXP1

2.62e-03211072C1292769
Diseasesocial deprivation, COVID-19

RIN2 ADAMTS17

2.62e-03211072EFO_0009696, MONDO_0100096
DiseaseBREAST CANCER

BRIP1 BRCA2

2.62e-03211072114480
Diseasedocosahexaenoic acid to total fatty acids percentage

JMJD1C MYRF

2.62e-03211072EFO_0022262
Diseasenucleus accumbens volume

BIRC6 USH2A

2.87e-03221072EFO_0006931
DiseaseLeber Congenital Amaurosis

SPATA7 IFT140

2.87e-03221072C0339527
Diseasedyslexia

TANC2 PDE4D HEATR5B AFG1L

2.91e-031621074EFO_0005424
Diseasediastolic blood pressure, systolic blood pressure

BRIP1 PDE4D ANK3 EMILIN3 PPARGC1A FBN1 CLCA2 NR3C2

3.08e-036701078EFO_0006335, EFO_0006336
Diseasesphingomyelin measurement

TDRD15 OR7G1 JMJD1C USH2A MYRF

3.49e-032781075EFO_0010118

Protein segments in the cluster

PeptideGeneStartEntry
SVASTSSIKCLQIPE

BUB1B

691

O60566
LPSKSVCNTSVLSSS

FAM222A

391

Q5U5X8
SGLPSLVTKLSASCT

ACOX2

421

Q99424
LTSKVCLDVTSVEPS

ANTXRL

246

A6NF34
SLATCPSSVSVEVSA

BIRC6

3231

Q9NR09
KTSSCSSLQREPVST

C2orf78

816

A6NCI8
SDVPTKCISTTESIE

CPSF2

516

Q9P2I0
TITTFLCPEKESTSA

ADGRG4

1371

Q8IZF6
KVRIICSASTPISSL

AFG1L

401

Q8WV93
LSSLAVSCPLTSLVS

ATP5MC2

41

Q06055
SGLVVTSLCKSSSLP

ARL2BP

141

Q9Y2Y0
NKKISTSCSVIPETS

ANKRD12

436

Q6UB98
ESSCKVTSPTTYVLD

AGTPBP1

1161

Q9UPW5
PILSATVTKRKATCT

ASPM

491

Q8IZT6
SSLTGETTPCSKVTA

ATP2C1

186

P98194
IPKCIESTPISATTE

ASXL3

1296

Q9C0F0
KSKVSTCLLVTDPRS

ADAMTS17

441

Q8TE56
SKAKPESVSTCSVTS

RAI1

546

Q7Z5J4
STTKIKSCSTEQPLT

QSER1

276

Q2KHR3
TFLKPCESESKTTRS

FMN1

811

Q68DA7
IVRLKPSCSTDSSFT

IQCK

11

Q8N0W5
TIPLSKISCTDSSIN

OR5H15

181

A6NDH6
LSFADICVTSTTIPK

OR7A5

66

Q15622
ATCTTPSEIDIKTAS

ANKRD34B

181

A5PLL1
LVPCKGSLSSSIQST

ANKRD27

36

Q96NW4
SVSTGSSRPSKICLV

NR3C2

591

P08235
ESKSPSKTTVRCLEA

LYVE1

306

Q9Y5Y7
LDKTCLSIVPSQTIS

EYS

1661

Q5T1H1
VKPSQTLSLTCTVSG

IGHV4-31

31

P0DP07
SVTPKEKVTITCRAS

IGKV6-21

31

A0A0C4DH24
PVKSTTSITDAKSCE

ANLN

296

Q9NQW6
TLSASLPLDSTVICS

JMJD1C

1511

Q15652
TLITACSSESLVSKG

KIAA1109

3371

Q2LD37
AATKCTSPSTELSIT

FICD

71

Q9BVA6
VKPTETLTLTCTVSG

IGHV2-26

31

A0A0B4J1V2
VKPSQTLSLTCTVSG

IGHV4-30-4

31

P0DP06
VKPSETLSLTCTVSG

IGHV4-61

31

A0A0C4DH41
NTTTLTCLAPSLTTD

PLXNA2

1091

O75051
SVTPKEKVTITCRAS

IGKV6D-21

31

A0A0A0MT36
VPTSCVNSLLDSTTI

OR14C36

76

Q8NHC7
SKTFSTCIPHLVVVT

OR14L1P

236

Q8NHC6
SLVESCFATPTSKID

OIT3

431

Q8WWZ8
KTLCTQDSESTEIPL

PDE4D

766

Q08499
PEDCSVSSITKVSVV

CWF19L2

211

Q2TBE0
VLTSKPSTVRLISCS

GANC

101

Q8TET4
TTCVSSSAPSKTSLI

FOXP1

256

Q9H334
SPDAVTTITSSKLHC

DDX28

346

Q9NUL7
SCIEKLSKTESISVP

EXPH5

981

Q8NEV8
SLPSKLFSCVSISVV

KCNS1

216

Q96KK3
VKPSDTLSLTCAVSG

IGHV4-28

31

A0A0C4DH34
KPSSTCSARLTVVIT

OR13C5

236

Q8NGS8
SSADTETKPAVCSVV

HIPK3

981

Q9H422
VKPSETLSLTCTVSG

IGHV4-59

31

P01825
ILSTPEGTSAACKSI

IGF2BP3

246

O00425
VKPSETLSLTCTVSG

IGHV4-38-2

31

P0DP08
CKVDSPTVNTTLRSL

KLC2

441

Q9H0B6
TIPLSKISCTDSSIN

OR5H1

181

A6NKK0
FPSLSSTTTILCTVE

DCHS2

1806

Q6V1P9
SCPQSETIISSLKID

BRIP1

1066

Q9BX63
ETLEASKQVSPCSTR

PPARGC1A

436

Q9UBK2
TTVLRIPSASSCQKA

OR6V1

221

Q8N148
LSFTDICLTTTTVPK

OR7G1

66

Q8NGA0
LVTSTLKTEEVTSCS

FBXO43

206

Q4G163
VDSTVKTVSPPTVCT

PAPOLG

591

Q9BWT3
ISSATTIKCAESLQP

BOD1L1

2156

Q8NFC6
SSVTTTESIKRSCPS

FAM189B

56

P81408
SGSKTPITTKLTVSC

HYDIN

5086

Q4G0P3
AATVTILSDLPSLCS

HEATR5B

1756

Q9P2D3
IACRSAPVSKTLSSS

C2CD2

461

Q9Y426
KVSKISPCDVSLETS

BRCA2

1941

P51587
STSVTVRDKTEESCP

COL19A1

21

Q14993
ECSSESTLDPTKTIC

FBN1

831

P35555
SEVECTVSSLLPGKT

FNDC3A

716

Q9Y2H6
TLACTPISSSKSDGL

AGAP7P

326

Q5VUJ5
SICFSPSISSTTIPK

AGAP7P

351

Q5VUJ5
LTTSSCVDVKSRIPV

ANK3

3901

Q12955
CMAALTVTLTVLSSP

HLA-DRB4

11

P13762
SVITRTTEITKCSPS

ATF7IP2

56

Q5U623
EKTLCLSTPSSSTVK

KMT2A

986

Q03164
VCSLISSDKLTVSSE

KLHL3

196

Q9UH77
CLVATTSSKIPSITD

GLIPR1L1

16

Q6UWM5
CTPSTTSAILDSLVA

EMILIN3

521

Q9NT22
RCSSSGSTISILPSK

IFT140

576

Q96RY7
PELSVSSVSTLKKIC

IPO13

541

O94829
TVSLVDTKSTSCVLS

WDR77

236

Q9BQA1
LSFVDICSSSSVVPK

OR5G3

66

P0C626
VSSQPCTKIESSSVL

PIAS2

436

O75928
SSSVLSKPCSVTVAS

PIAS2

446

O75928
SSDKEATVPCTEILT

MIA2

346

Q96PC5
CPSSVLTTVKEKASA

OR1M1

261

Q8NGA1
SCADIFSTSTTVPKA

OR1P1

81

Q8NH06
LALTDICFTSTTVPK

OR1Q1

66

Q15612
TSPCAVSSATLKDLE

GOLGA8A

21

A7E2F4
CSTSKPTSITTLEAA

USH2A

4341

O75445
SMSVSICPSSTEVLK

UTY

831

O14607
LSCEVQSSPTTLLVT

SLC9A6

131

Q92581
VSKSIGCTPDTVASS

SGK2

331

Q9HBY8
LTKAATDITTLCPSS

TCP11X1

246

B4DZS4
LTKAATDITTLCPSS

TCP11X2

151

Q5H9J9
ESKTPVSSCTIKSFT

TDRD15

1711

B5MCY1
CSTLLIDKVSTPATT

SYNPO

396

Q8N3V7
PCLTVSVELLSMSSS

HUS1

111

O60921
PLDSSCKESSVSVTS

NCOA3

641

Q9Y6Q9
CKESSVSVTSPSGVS

NCOA3

646

Q9Y6Q9
LSLPVCTVSLVSSVS

SLC25A47

56

Q6Q0C1
TSAITQRISPCSTLT

TANC2

121

Q9HCD6
STLAVALCSTVPSLA

SLC43A3

356

Q8NBI5
SSVSTVSTICPGDLK

PDLIM3

151

Q53GG5
STSRVFTTLVLCDKP

SKIV2L

866

Q15477
SCSSTVSVKEELSPV

PLAGL2

261

Q9UPG8
VSITKDSELPTCSCL

TET1

1411

Q8NFU7
SPKGVSCSEVTASSL

ADD2

171

P35612
PTTVSAKTDISICSG

CLCA2

381

Q9UQC9
TVVGPDSSKTLLCLS

PDCD11

1206

Q14690
SIKTRTPSELECSQT

RIN2

251

Q8WYP3
TLTQDSLPITVCSLS

RNASE13

101

Q5GAN3
STLCENSVSELLTPT

ZXDB

741

P98169
RSSELAVTPSTAKCQ

SRRM5

206

B3KS81
PVICSTSAASLKSLT

SCML2

321

Q9UQR0
ACVVPTATTKVPLST

SPATC1

246

Q76KD6
TVSPSDTANCSVTKI

SOBP

331

A7XYQ1
PEDCTVTQSKSSLTI

SPATA31D1

306

Q6ZQQ2
SKTSSIEECSSLPVF

ZNF292

1556

O60281
KTVSSSEVSVCSEPV

PIK3CD

356

O00329
SAKAAVDCSVPVSVS

SPATA7

61

Q9P0W8
DIPSSLLTSEKSTAC

ZMIZ2

786

Q8NF64
TTTCSLSPDSAILKL

ZNF827

201

Q17R98
LTVDTDTLTPSSTLC

ZXDA

726

P98168
VGVSEVTASKPCLSS

ZNF548

66

Q8NEK5
CIQLSSSTSTPTLAE

WNK1

1506

Q9H4A3
AVAPSKLLTSTTSTC

WNK1

1696

Q9H4A3
SLKACLVTTVTSSGP

WDR11

1031

Q9BZH6
SVCSSPLIRTKFTGT

SNX16

66

P57768
RTQTCTSSSLSPTKI

TRIM8

311

Q9BZR9
SSSPVSVVLCSLRSK

MYRF

1066

Q9Y2G1