Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondihydropyrimidinase activity

DPYSL2 DPYSL3 DPYSL4 CRMP1

1.07e-0861054GO:0004157
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides

DPYSL2 DPYSL3 DPYSL4 CRMP1

1.25e-06161054GO:0016812
GeneOntologyBiologicalProcesspyrimidine nucleobase catabolic process

DPYSL2 DPYSL3 DPYSL4 CRMP1

4.54e-0881064GO:0006208
GeneOntologyBiologicalProcessnucleobase catabolic process

DPYSL2 DPYSL3 DPYSL4 CRMP1

4.55e-07131064GO:0046113
GeneOntologyBiologicalProcesspyrimidine nucleobase metabolic process

DPYSL2 DPYSL3 DPYSL4 CRMP1

4.49e-06221064GO:0006206
GeneOntologyBiologicalProcessnucleobase metabolic process

DPYSL2 DPYSL3 DPYSL4 CRMP1

8.35e-05451064GO:0009112
GeneOntologyBiologicalProcesspyrimidine-containing compound catabolic process

DPYSL2 DPYSL3 DPYSL4 CRMP1

9.11e-05461064GO:0072529
DomainHydantoinase/dihydroPyrase

DPYSL2 DPYSL3 DPYSL4 CRMP1

1.57e-0861084IPR011778
Domain-

DPYSL2 DPYSL3 DPYSL4 CRMP1

7.27e-08810842.30.40.10
DomainAmidohydro_1

DPYSL2 DPYSL3 DPYSL4 CRMP1

2.16e-07101084PF01979
DomainMetal-dep_hydrolase_composite

DPYSL2 DPYSL3 DPYSL4 CRMP1

2.16e-07101084IPR011059
DomainAmidohydro-rel

DPYSL2 DPYSL3 DPYSL4 CRMP1

3.38e-07111084IPR006680
DomainMetal_Hydrolase

DPYSL2 DPYSL3 DPYSL4 CRMP1

1.03e-05241084IPR032466
Domain-

RASA4 RASA4B

9.90e-05310824.10.1130.10
DomainFurin-like_2

RSPO3 RSPO1

1.97e-0441082PF15913
DomainDysFC

FER1L5 TECPR1

1.97e-0441082SM00694
DomainDysFN

FER1L5 TECPR1

1.97e-0441082SM00693
DomainPeroxin/Ferlin

FER1L5 TECPR1

1.97e-0441082IPR006614
DomainHyaluronidase

SPAM1 HYAL3

3.28e-0451082IPR018155
DomainGlyco_hydro_56

SPAM1 HYAL3

3.28e-0451082PF01630
DomainTSP_1

ADAMTS3 RSPO3 C7 RSPO1

4.84e-04631084PF00090
Domain-

TDRD15 TDRD6

4.89e-04610822.40.50.90
DomainStaphylococal_nuclease_OB-fold

TDRD15 TDRD6

4.89e-0461082IPR016071
DomainEFhand_Ca_insen

ACTN4 ACTN3

4.89e-0461082PF08726
DomainEF-hand_Ca_insen

ACTN4 ACTN3

4.89e-0461082IPR014837
DomainTSP1

ADAMTS3 RSPO3 C7 RSPO1

5.46e-04651084SM00209
DomainTSP1_rpt

ADAMTS3 RSPO3 C7 RSPO1

5.46e-04651084IPR000884
DomainTSP1

ADAMTS3 RSPO3 C7 RSPO1

5.46e-04651084PS50092
DomainMACPF_2

MPEG1 C7

6.83e-0471082PS51412
DomainMACPF_1

MPEG1 C7

6.83e-0471082PS00279
DomainBTK

RASA4 RASA4B

1.16e-0391082SM00107
DomainZnf_Btk_motif

RASA4 RASA4B

1.16e-0391082IPR001562
DomainBTK

RASA4 RASA4B

1.16e-0391082PF00779
DomainZF_BTK

RASA4 RASA4B

1.16e-0391082PS51113
DomainMACPF

MPEG1 C7

1.76e-03111082PF01823
DomainMACPF

MPEG1 C7

2.11e-03121082IPR020864
DomainMACPF

MPEG1 C7

2.11e-03121082SM00457
Domainfn3

BOC MID2 CNTN6 CNTN1 EPHA1

2.51e-031621085PF00041
DomainRasGAP

RASA4 RASA4B

2.88e-03141082SM00323
DomainTUDOR

TDRD15 TDRD6

2.88e-03141082PF00567
DomainRasGAP_CS

RASA4 RASA4B

2.88e-03141082IPR023152
Domain7tm_2

PTH1R ADGRE4P ADGRF1

3.03e-03501083PF00002
DomainG_PROTEIN_RECEP_F2_2

PTH1R ADGRE4P ADGRF1

3.03e-03501083PS00650
DomainRasGAP

RASA4 RASA4B

3.31e-03151082PF00616
DomainRAS_GTPASE_ACTIV_1

RASA4 RASA4B

3.31e-03151082PS00509
DomainRAS_GTPASE_ACTIV_2

RASA4 RASA4B

3.31e-03151082PS50018
DomainGlycoside_hydrolase_SF

SPAM1 MANBA HYAL3

3.57e-03531083IPR017853
DomainGuanylate_kinase_CS

MAGI3 MPP4

3.77e-03161082IPR020590
Domain-

RASA4 RASA4B

3.77e-031610821.10.506.10
DomainFN3

BOC MID2 CNTN6 CNTN1 EPHA1

4.43e-031851085SM00060
DomainRasGAP_dom

RASA4 RASA4B

4.77e-03181082IPR001936
DomainFurin_repeat

RSPO3 RSPO1

4.77e-03181082IPR006212
DomainFU

RSPO3 RSPO1

4.77e-03181082SM00261
DomainIg_I-set

BOC ISLR CNTN6 SIGLEC11 CNTN1

4.95e-031901085IPR013098
DomainI-set

BOC ISLR CNTN6 SIGLEC11 CNTN1

4.95e-031901085PF07679
DomainGPCR_2_secretin-like

PTH1R ADGRE4P ADGRF1

5.07e-03601083IPR000832
DomainG_PROTEIN_RECEP_F2_4

PTH1R ADGRE4P ADGRF1

5.31e-03611083PS50261
PathwayREACTOME_CRMPS_IN_SEMA3A_SIGNALING

DPYSL2 DPYSL3 DPYSL4 CRMP1

1.02e-0615764MM15031
PathwayREACTOME_CRMPS_IN_SEMA3A_SIGNALING

DPYSL2 DPYSL3 DPYSL4 CRMP1

1.35e-0616764M8245
PathwayREACTOME_SEMAPHORIN_INTERACTIONS

DPYSL2 DPYSL3 DPYSL4 CRMP1

1.61e-0451764MM14967
Pubmed

The Ulip family phosphoproteins--common and specific properties.

DPYSL2 DPYSL3 DPYSL4 CRMP1

9.83e-11411149652388
Pubmed

Differential expression of dihydropyrimidinase-related protein genes in developing and adult enteric nervous system.

DPYSL2 DPYSL3 DPYSL4 CRMP1

9.83e-114111410664068
Pubmed

A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution.

DPYSL2 DPYSL3 DPYSL4 CRMP1

4.90e-10511148973361
Pubmed

Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family.

DPYSL2 DPYSL3 DPYSL4 CRMP1

1.47e-096111410956643
Pubmed

CRMP-2 binds to tubulin heterodimers to promote microtubule assembly.

DPYSL2 DPYSL3 DPYSL4 CRMP1

6.81e-098111412134159
Pubmed

Aberrant expression of dihydropyrimidinase related proteins-2,-3 and -4 in fetal Down syndrome brain.

DPYSL2 DPYSL3 DPYSL4

3.16e-083111311771764
Pubmed

Amino- and carboxyl-terminal domains of Filamin-A interact with CRMP1 to mediate Sema3A signalling.

DPYSL3 DPYSL4 CRMP1

1.26e-074111325358863
Pubmed

Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo.

DPYSL2 DPYSL3 CRMP1

3.15e-075111316611631
Pubmed

CRMP2 mediates Sema3F-dependent axon pruning and dendritic spine remodeling.

DPYSL2 DPYSL3 CRMP1

2.62e-069111331919978
Pubmed

CRMP1 and CRMP4 are required for proper orientation of dendrites of cerebral pyramidal neurons in the developing mouse brain.

DPYSL3 CRMP1

1.01e-052111227836492
Pubmed

LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling.

RSPO3 RSPO1

1.01e-052111221909076
Pubmed

Axonal morphogenesis controlled by antagonistic roles of two CRMP subtypes in microtubule organization.

DPYSL3 CRMP1

1.01e-052111212814366
Pubmed

Phosphorylation of CRMP2 (collapsin response mediator protein 2) is involved in proper dendritic field organization.

DPYSL2 CRMP1

1.01e-052111222279220
Pubmed

Loss of SMURF2 expression enhances RACK1 stability and promotes ovarian cancer progression.

RACK1 SMURF2

1.01e-052111237828084
Pubmed

CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.

RASA4 RASA4B

1.01e-052111211448776
Pubmed

Loss of CRMP1 and CRMP2 results in migration defects of Purkinje cells in the X lobule of the mouse cerebellum.

DPYSL2 CRMP1

1.01e-052111235219721
Pubmed

Acidic hyaluronidase activity is present in mouse sperm and is reduced in the absence of SPAM1: evidence for a role for hyaluronidase 3 in mouse and human sperm.

SPAM1 HYAL3

1.01e-052111220586096
Pubmed

Mouse pups lacking collapsin response mediator protein 4 manifest impaired olfactory function and hyperactivity in the olfactory bulb.

DPYSL3 DPYSL4

1.01e-052111226118640
Pubmed

Rspo1 and Rspo3 are required for sensory lineage neural crest formation in mouse embryos.

RSPO3 RSPO1

1.01e-052111237767857
Pubmed

The six hyaluronidase-like genes in the human and mouse genomes.

SPAM1 HYAL3

1.01e-052111211731267
Pubmed

Characterization of interaction and ubiquitination of phosphoenolpyruvate carboxykinase by E3 ligase UBR5.

UBR5 PCK1

1.01e-052111230552140
Pubmed

A WNT/beta-catenin signaling activator, R-spondin, plays positive regulatory roles during skeletal myogenesis.

RSPO3 RSPO1

1.01e-052111221252233
Pubmed

The downregulation of SnoN expression in human renal proximal tubule epithelial cells under high-glucose conditions is mediated by an increase in Smurf2 expression through TGF-β1 signaling.

SKIL SMURF2

1.01e-052111226743567
Pubmed

Phosphorylation of CRMP2 is involved in proper bifurcation of the apical dendrite of hippocampal CA1 pyramidal neurons.

DPYSL2 DPYSL3

1.01e-052111222826151
Pubmed

Tetrodotoxin-resistant voltage-gated sodium channel Nav 1.8 constitutively interacts with ankyrin G.

ANK3 SCN10A

1.01e-052111224903831
Pubmed

An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.

RASA4 RASA4B

1.01e-052111216041389
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SPAM1 ATXN7L1 TAF1C ECT2L SKIL RACK1 ACAD11 UBR5 PRPF4 ARID2 FECH ZBTB10 ELF3 ZMYM3

1.32e-0511161111431753913
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DPYSL2 ANK3 MID2 ATXN7L1 SAMD12 BARD1 MAGI3 ANKMY1 MICU1 ZNF532 FECH TSPAN4 CYB5D1 PRORP ZRANB1 SMURF2

2.07e-0514891111628611215
Pubmed

Phosphorylation of CRMP2 is required for migration and positioning of Purkinje cells: Redundant roles of CRMP1 and CRMP4.

DPYSL2 CRMP1

3.02e-053111232156571
Pubmed

Expression of collapsin response mediator proteins 1, 2 and 5 is differentially regulated in newly generated and mature neurons of the adult olfactory system.

DPYSL2 CRMP1

3.02e-053111215926912
Pubmed

c-Ski, Smurf2, and Arkadia as regulators of TGF-beta signaling: new targets for managing myofibroblast function and cardiac fibrosis.

SKIL SMURF2

3.02e-053111219898560
Pubmed

R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis.

RSPO3 RSPO1

3.02e-053111215469841
Pubmed

α-Actinin-3 deficiency is associated with reduced bone mass in human and mouse.

ACTN4 ACTN3

3.02e-053111221784188
Pubmed

RSPOs facilitated HSC activation and promoted hepatic fibrogenesis.

RSPO3 RSPO1

3.02e-053111227572318
Pubmed

CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.

RASA4 RASA4B

3.02e-053111225637021
Pubmed

The human non-muscle alpha-actinin protein encoded by the ACTN4 gene suppresses tumorigenicity of human neuroblastoma cells.

ACTN4 ACTN3

3.02e-053111210656685
Pubmed

A complex between contactin-1 and the protein tyrosine phosphatase PTPRZ controls the development of oligodendrocyte precursor cells.

CNTN6 CNTN1

3.02e-053111221969550
Pubmed

Recurrent R-spondin fusions in colon cancer.

RSPO3 RSPO1

3.02e-053111222895193
Pubmed

Proteomic analysis of neonatal mouse brain: evidence for hypoxia- and ischemia-induced dephosphorylation of collapsin response mediator proteins.

DPYSL2 DPYSL3

3.02e-053111218471005
Pubmed

Activation of the Intracellular Pattern Recognition Receptor NOD2 Promotes Acute Myeloid Leukemia (AML) Cell Apoptosis and Provides a Survival Advantage in an Animal Model of AML.

FLT3 NOD2

3.02e-053111232094205
Pubmed

Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin.

ACTN4 ACTN3

3.02e-05311128104223
Pubmed

CRMP1 and CRMP2 have synergistic but distinct roles in dendritic development.

DPYSL2 CRMP1

3.02e-053111227480924
Pubmed

Structure of the human UBR5 E3 ubiquitin ligase.

UBR5 PCK1

3.02e-053111237040767
Pubmed

CRMP2 tethers kainate receptor activity to cytoskeleton dynamics during neuronal maturation.

DPYSL2 DPYSL3

6.03e-054111224227739
Pubmed

Dynamic expression of R-spondin family genes in mouse development.

RSPO3 RSPO1

6.03e-054111217035101
Pubmed

Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.

RASA4 RASA4B

6.03e-054111221460216
Pubmed

Glycosylphosphatidylinositol anchored recognition molecules that function in axonal fasciculation, growth and guidance in the nervous system.

CNTN6 CNTN1

6.03e-05411121838307
Pubmed

Mesenchyme governs hair follicle induction.

RSPO3 RSPO1

6.03e-054111237982496
Pubmed

Alpha-actinin and vinculin in human neutrophils: reorganization during adhesion and relation to the actin network.

ACTN4 ACTN3

6.03e-05411121629252
Pubmed

TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation.

SKIL SMURF2

6.03e-054111211389444
Pubmed

NOD-like receptor signaling and inflammasome-related pathways are highlighted in psoriatic epidermis.

NOD2 PYCARD

6.03e-054111226976200
Pubmed

Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis.

ACTN4 ACTN3

6.03e-054111216807302
Pubmed

Sodium channel beta1 subunit-mediated modulation of Nav1.2 currents and cell surface density is dependent on interactions with contactin and ankyrin.

ANK3 CNTN1

6.03e-054111214761957
Pubmed

Expression analysis of six paralogous human hyaluronidase genes clustered on chromosomes 3p21 and 7q31.

SPAM1 HYAL3

6.03e-054111210493834
Pubmed

A conditional allele of Rspo3 reveals redundant function of R-spondins during mouse limb development.

RSPO3 RSPO1

6.03e-054111222610508
Pubmed

Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding.

RASA4 RASA4B

6.03e-054111216234249
Pubmed

A functional coupling between CRMP1 and Nav1.7 for retrograde propagation of Semaphorin3A signaling.

DPYSL2 CRMP1

6.03e-054111228254884
Pubmed

R-spondin-3 induces secretory, antimicrobial Lgr5+ cells in the stomach.

RSPO3 RSPO1

6.03e-054111231235935
Pubmed

E3 Ligase Trim21 Ubiquitylates and Stabilizes Keratin 17 to Induce STAT3 Activation in Psoriasis.

DPYSL2 DPYSL3 CRMP1 RACK1 CNTN1

7.54e-05135111529859926
Pubmed

CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages.

NOD2 PYCARD

1.00e-045111227670879
Pubmed

Cryopyrin activates the inflammasome in response to toxins and ATP.

NOD2 PYCARD

1.00e-045111216407890
Pubmed

RACK1 regulates centriole duplication by controlling localization of BRCA1 to the centrosome in mammary tissue-derived cells.

BARD1 RACK1

1.00e-045111230617304
Pubmed

R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6.

KREMEN1 RSPO1

1.00e-045111217804805
Pubmed

Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner.

ACTN4 ACTN3

1.00e-045111215841212
Pubmed

p80 ROKalpha binding protein is a novel splice variant of CRMP-1 which associates with CRMP-2 and modulates RhoA-induced neuronal morphology.

DPYSL2 CRMP1

1.00e-045111212482610
Pubmed

The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin.

ACTN4 ACTN3

1.00e-045111212837758
Pubmed

LGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressor.

RSPO3 RSPO1

1.00e-045111222615920
Pubmed

Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interaction.

ACTN4 ACTN3

1.00e-045111219943616
Pubmed

Downregulation of SnoN expression in obstructive nephropathy is mediated by an enhanced ubiquitin-dependent degradation.

SKIL SMURF2

1.00e-045111216959829
Pubmed

Human rhomboid family-1 suppresses oxygen-independent degradation of hypoxia-inducible factor-1α in breast cancer.

RHBDF1 RACK1

1.00e-045111224648344
Pubmed

Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain.

DPYSL2 CRMP1

1.00e-045111215834957
Pubmed

Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.

SCN10A CNTN1

1.50e-046111216029194
Pubmed

Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.

ACTN4 ACTN3

1.50e-046111218425115
Pubmed

The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway.

ACTN4 ACTN3

1.50e-046111222693585
Pubmed

Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.

MTMR10 UBR5

1.50e-046111232876667
Pubmed

Reconstitution of R-spondin:LGR4:ZNRF3 adult stem cell growth factor signaling complexes with recombinant proteins produced in Escherichia coli.

RSPO3 RSPO1

1.50e-046111224050775
Pubmed

NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma.

NOD2 PYCARD

1.50e-046111228442553
Pubmed

Engineering high-potency R-spondin adult stem cell growth factors.

RSPO3 RSPO1

1.50e-046111225504990
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

BOC FLT3 ISLR CNTN6 CNTN1

1.77e-04162111525826454
Pubmed

HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis.

RACK1 ACAD11 FECH ZRANB1

1.78e-0487111433711283
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

RHBDF1 ANK3 MPEG1 OAS1 RTN4IP1 ACTN4 NCOA4 CRMP1 RACK1 FECH ZBTB10 LMBRD1

1.84e-0410841111211544199
Pubmed

Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin.

DPYSL3 ACTN4 PTH1R RACK1

2.03e-049011141602151
Pubmed

R-spondin 1/dickkopf-1/beta-catenin machinery is involved in testicular embryonic angiogenesis.

KREMEN1 RSPO1

2.10e-047111225910078
Pubmed

A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide.

NOD2 PYCARD

2.10e-047111218511561
Pubmed

MDP-induced interleukin-1beta processing requires Nod2 and CIAS1/NALP3.

NOD2 PYCARD

2.10e-047111217403772
Pubmed

Nogo-A at CNS paranodes is a ligand of Caspr: possible regulation of K(+) channel localization.

CNTN6 CNTN1

2.10e-047111214592966
Pubmed

Spatiotemporal expression patterns of R-spondins and their receptors, Lgrs, in the developing mouse telencephalon.

RSPO3 RSPO1

2.10e-047111237651925
Pubmed

Addendum: defective Dock2 expression in a subset of ASC-deficient mouse lines.

NOD2 PYCARD

2.10e-047111222905357
Pubmed

The Cag pathogenicity island and interaction between TLR2/NOD2 and NLRP3 regulate IL-1β production in Helicobacter pylori infected dendritic cells.

NOD2 PYCARD

2.10e-047111223818043
Pubmed

Differential activities and mechanisms of the four R-spondins in potentiating Wnt/β-catenin signaling.

RSPO3 RSPO1

2.10e-047111229752411
Pubmed

Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice.

NOD2 PYCARD

2.10e-047111223209417
Pubmed

RIPK3 Restricts Myeloid Leukemogenesis by Promoting Cell Death and Differentiation of Leukemia Initiating Cells.

FLT3 PYCARD

2.10e-047111227411587
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DPYSL2 ANK3 TAF1C MAGI3 ACTN4 SKIL MTMR10 CRMP1 MICU1 ZNF532 SACS WDR17 SMURF2

2.36e-0412851111335914814
Pubmed

RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids.

NOD2 PYCARD

2.79e-048111223064150
Pubmed

R-spondins/Lgrs expression in tooth development.

RSPO3 RSPO1

2.79e-048111224616052
Pubmed

Mice deficient in alpha-actinin-4 have severe glomerular disease.

ACTN4 ACTN3

2.79e-048111212782671
Pubmed

Associations of polymorphisms of eight muscle- or metabolism-related genes with performance in Mount Olympus marathon runners.

ACTN3 BDKRB2

2.79e-048111220044476
Pubmed

Ubiquitination of alpha-synuclein filaments by Nedd4 ligases.

ZRANB1 SMURF2

2.79e-048111230021006
Pubmed

Comparative genome mapping in the sequence-based era: early experience with human chromosome 7.

RASA4 RASA4B

2.79e-048111210810084
Pubmed

CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function.

ACTN4 ACTN3

2.79e-048111220215401
GeneFamilyActinins

ACTN4 ACTN3

1.01e-0447521112
GeneFamilyFibronectin type III domain containing

BOC MID2 CNTN6 CNTN1 EPHA1

5.34e-04160755555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

BOC ISLR CNTN6 SIGLEC11 CNTN1

5.50e-04161755593
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

RASA4 RASA4B

7.48e-0410752830
CoexpressionGSE30083_SP1_VS_SP4_THYMOCYTE_DN

MANBA OAS1 NDRG3 ADCY7 CRMP1 FAM78A SMURF2

2.22e-052001107M5030
CoexpressionGSE30083_SP2_VS_SP4_THYMOCYTE_DN

MPEG1 OAS1 ADCY7 FAM78A MPP4 CD38 SHCBP1L

2.22e-052001107M5035
CoexpressionGSE30083_SP1_VS_SP3_THYMOCYTE_DN

ANK3 OAS1 NDRG3 CRMP1 FAM78A PYCARD SMURF2

2.22e-052001107M5026
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BOC DPYSL3 ADAMTS3 SVEP1 RSPO3 C7 RSPO1

4.73e-071901107efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC DPYSL3 ISLR SVEP1 RSPO3 C7 RSPO1

5.44e-071941107da926441053b499cb5107ccb116fb1b3844d82b7
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BOC DPYSL3 ISLR SVEP1 RSPO3 C7 RSPO1

5.44e-07194110702b8102be9414d6964cd71019613edff6d88b893
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC DPYSL3 ISLR SVEP1 RSPO3 C7 RSPO1

5.44e-07194110754a7f693966b5c02f6b248950ddb5fa32af3ae67
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC DPYSL3 ISLR SVEP1 RSPO3 C7 RSPO1

5.44e-071941107f34b3bbdebf56f66ff499e390e5515a4a4093f90
ToppCellbackground-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ANK3 ISLR PTH1R SVEP1 RSPO3 C7 PCK1

6.24e-07198110779f32f965aed6a10c5cb803173e3db7b32e07a91
ToppCell5'-Adult-LargeIntestine-Mesenchymal-stromal_related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC PTH1R RSPO3 ZNF532 C7 PRSS48

4.87e-061751106b8995e7ada85ba959f06264a0295b61e390c4e6c
ToppCellfacs|World / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL2 DPYSL3 ISLR MARF1 C7 EPHA1

4.87e-06175110653e96956019f984decc1c81376ebc88fbf3c4d40
ToppCell5'-Adult-LargeIntestine-Mesenchymal-stromal_related-T_reticular|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC PTH1R RSPO3 ZNF532 C7 PRSS48

4.87e-0617511067ae76bd3b4f610b2f98716a4456437cd3696b686
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC ANK3 ISLR RSPO3 C7 CNTN1

5.20e-0617711067af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BOC DPYSL3 ISLR SVEP1 RSPO3 RSPO1

5.72e-061801106c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BOC DPYSL3 ISLR SVEP1 RSPO3 RSPO1

5.72e-06180110632c6a3886428d82fb4355d987c6d2645f333447b
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL3 ISLR SVEP1 RSPO3 C7 RSPO1

5.91e-061811106269b39ac65790061d54eab47a8eeb024403f0348
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL3 ISLR SVEP1 RSPO3 C7 RSPO1

5.91e-061811106cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL3 ISLR SVEP1 RSPO3 C7 RSPO1

5.91e-061811106c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCellfacs-Skin-nan-24m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISLR ADCY7 SVEP1 TSPAN4 C7 RSPO1

6.70e-0618511068433a337625ff8398520e223ef92bf9bb0beb14c
ToppCellfacs-Skin-nan-24m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISLR ADCY7 SVEP1 TSPAN4 C7 RSPO1

6.70e-061851106049d793d043d5d434f143025de49dd210d18756c
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

BOC DPYSL3 ISLR SVEP1 RSPO3 C7

6.70e-061851106fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCellfacs-Skin-nan-24m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISLR ADCY7 SVEP1 TSPAN4 C7 RSPO1

6.70e-06185110663200c42565eea596f9b00728e70e544b8d50a7f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BOC DPYSL3 ADAMTS3 SVEP1 RSPO3 RSPO1

7.34e-061881106ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC DPYSL3 ISLR BDKRB2 SVEP1 C7

7.57e-061891106f7d57723b8fb0f1e1485f51e3eff93ec0f39761e
ToppCellfacs-MAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL3 ISLR SVEP1 RSPO3 C7 RSPO1

8.03e-061911106b4fba92f9bd1354a07fedfca7304a3757e6d5beb
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC ISLR SVEP1 RSPO3 TSPAN4 C7

8.03e-0619111064e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

BOC DPYSL3 ISLR SVEP1 RSPO3 C7

8.28e-061921106e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell10x3'2.3-week_14-16-Myeloid_DC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

DPYSL2 FLT3 MPEG1 OAS1 ARPC3 PYCARD

8.53e-061931106c6633aca0eb4d699c4d3da3199b84bebd87e2d31
ToppCelldroplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL3 ADAMTS3 ISLR PTH1R SVEP1 RSPO3

8.53e-06193110659b8186d0221fba06a16157e9d148399ed801f38
ToppCelldroplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL3 ADAMTS3 ISLR PTH1R SVEP1 RSPO3

8.53e-061931106dc92680b4bb9fc26430c92e03adb839c8c3b3b98
ToppCelldroplet-Pancreas-Endocrine-21m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL3 ADAMTS3 ISLR PTH1R SVEP1 RSPO3

8.53e-06193110603678162648bd5b1d65a5450b60c8863edbf95c7
ToppCell10x3'2.3-week_14-16-Myeloid_DC-DC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

DPYSL2 FLT3 MPEG1 OAS1 ARPC3 PYCARD

8.53e-061931106a32791b4bdb7c5f2b4cc75b660321ab75c4fac9b
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC ISLR SVEP1 CRMP1 TSPAN4 C7

8.78e-061941106e2db75f4de114631b8bda4e188f84446545538b7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC ADAMTS3 SVEP1 RSPO3 C7 CNTN1

8.78e-061941106c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC ADAMTS3 SVEP1 RSPO3 C7 CNTN1

9.04e-0619511063c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC ISLR SVEP1 RSPO3 C7 CNTN1

9.58e-0619711062744cc94883c5d0424677cf5093bbab622933e9b
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-stromal_related|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPYSL3 ISLR SVEP1 RSPO3 C7 RSPO1

9.58e-061971106ea9332adf753d7e92f89654320543abb9e6142aa
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-stromal_related-T_reticular|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPYSL3 ISLR SVEP1 RSPO3 C7 RSPO1

9.86e-06198110611f21a4a97da10fc6ae604cb627aa3af749d9dff
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

ANK3 ISLR PTH1R SVEP1 RSPO3 C7

9.86e-061981106bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC ISLR SVEP1 RSPO3 C7 CNTN1

1.01e-051991106103f657132e830a0e5efeb745afb4b77c208a1fa
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BOC DPYSL3 ISLR SVEP1 RSPO3 C7

1.01e-051991106f835e7ffe976843b0edbf695762d463da85793f3
ToppCell356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

BOC DPYSL3 ISLR SVEP1 RSPO3 C7

1.01e-051991106675f7c56b03a7918e2d9ca99440df6f27ad8e838
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BOC DPYSL3 ISLR SVEP1 RSPO3 C7

1.01e-051991106993fa050a095017135a6e723c77cd38b9d782e58
ToppCell356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

BOC DPYSL3 ISLR SVEP1 RSPO3 C7

1.01e-05199110697d74985018816754d11a55b9fb689690ecb1374
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

BOC DPYSL3 ISLR SVEP1 RSPO3 C7

1.04e-052001106954fee8425673e76198be414f5f6c4e3597c1919
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Fibroblasts|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

BOC DPYSL3 ISLR SVEP1 RSPO3 C7

1.04e-052001106bfa73bc5f8a6c7de8353ca049a921ef19f7f4437
ToppCellBiopsy_Other_PF-Mesenchymal-PLIN2+_Fibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

BOC ISLR SVEP1 RSPO3 C7 RSPO1

1.04e-0520011060aa316b71f195ecf17ee897e307f8928a755a637
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer|World / Primary Cells by Cluster

DPYSL2 DPYSL3 ANK3 CRMP1 RSPO3 CNTN1

1.04e-052001106db10f76938af553d1a2275bb02ef75dff3c3135b
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer-21|World / Primary Cells by Cluster

DPYSL2 DPYSL3 ANK3 CRMP1 RSPO3 CNTN1

1.04e-05200110630a3e4aee12ec1b5acdce90f86c9733c27a7f6fc
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BOC DPYSL3 ADAMTS3 SVEP1 RSPO3 C7

1.04e-05200110674e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|356C / Donor, Lineage, Cell class and subclass (all cells)

BOC ISLR FRRS1 C7 TDRD6

4.16e-051551105e1a20e88b9c0eaf7ca7004acc0eda096d1588563
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 MPEG1 ADCY7 ZNF532 ADGRE4P

4.42e-051571105ec433d2fe827abdb647be4176c231b7052482b6f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BOC MTMR10 CRMP1 PYCARD ADGRF1

4.56e-0515811051cefb82b9bf79c687a119be568cfc15b14c6e040
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 MYO7B SVEP1 TDRD6 WDR17

4.84e-051601105c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 MYO7B SVEP1 TDRD6 WDR17

4.84e-05160110525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell368C-Fibroblasts-Fibroblast-E|368C / Donor, Lineage, Cell class and subclass (all cells)

BOC ACTN3 SVEP1 RSPO3 C7

5.13e-051621105e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell368C-Fibroblasts-Fibroblast-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

BOC ACTN3 SVEP1 RSPO3 C7

5.13e-051621105ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCelldroplet-Marrow-BM-30m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPEG1 FAM78A FECH ADGRE4P ZBTB10

5.13e-05162110575df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS3 GDPD2 ADCY7 RSPO3 HYAL3

5.29e-051631105d2fcd6f561748f7d29a051c504f016952ba32d0f
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-red_blood_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA4 FMO6P HYAL3 FECH TDRD6

5.60e-05165110562dd54dfbec7f43a41546a1fec719545c2608a36
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-red_blood_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA4 C16orf46 FECH CYB5D1

6.15e-058611041f44bb41835445aa60a2e3c31616c5847447a246
ToppCellfacs-Liver-Non-hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT3 MPEG1 RASA4 PYCARD ADGRE4P

6.45e-051701105f08aa6168ff0c20b2083dbf588dd3294e3d9580e
ToppCellNS-critical-d_0-4-Myeloid-Monocyte-derived_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MYO7B TAF1C RTN4IP1 CD38 FECH

6.45e-051701105adf73bdc049d508f8873c22539db2ca92052a97b
ToppCellfacs-Liver-Non-hepatocytes-24m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT3 MPEG1 RASA4 PYCARD ADGRE4P

6.82e-05172110566823536288c7009ce01b5177794a3e874e94570
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC ISLR SVEP1 RSPO3 C7

7.20e-0517411059c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC ISLR SVEP1 RSPO3 C7

7.20e-051741105bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

BOC ISLR SVEP1 C7 TDRD6

7.60e-051761105bfa1633e1b7a8a2f04d37fa07284fe9bc0199f46
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI3 SVEP1 CNTN6 ELF3 C7

7.81e-051771105b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

BOC ISLR SVEP1 C7 TDRD6

7.81e-0517711053d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-cDC1|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT3 MPEG1 ADCY7 NOD2 SIGLEC11

7.81e-051771105345cebc19f93970a9a46be139208b300081f5493
ToppCell356C-Fibroblasts-Fibroblast-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

BOC ADAMTS3 ISLR SVEP1 RSPO3

8.02e-051781105a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell356C-Fibroblasts-Fibroblast-E|356C / Donor, Lineage, Cell class and subclass (all cells)

BOC ADAMTS3 ISLR SVEP1 RSPO3

8.02e-051781105371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCellfacs-Pancreas-Endocrine-24m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL3 ISLR SVEP1 RSPO3 C7

8.23e-0517911056f51a4580c06fc55cc764052c9b26f7c55660282
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK3 SAMD12 ELF3 ADGRF1 SLC6A14

8.23e-0517911056e965e424eebef50f0202cff75f458be395cfca1
ToppCell-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ISLR PTH1R SVEP1 C7 RSPO1

8.23e-05179110510fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCellfacs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL3 ISLR SVEP1 RSPO3 C7

8.23e-051791105f14440f6ce9b4fcdd4bcb2488b949f9a0e17bc23
ToppCellfacs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL3 ISLR SVEP1 RSPO3 C7

8.23e-051791105a6ce1fa338d4905bd6afef00763ac83e916a0b37
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MPEG1 ADCY7 FAM78A CD38 FER1L5

8.23e-051791105ce95b601bf17ae8167d382a105384b9e65e9407f
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC ISLR RSPO3 TSPAN4 C7

8.67e-051811105e1ae9ada60ec89e7a7cde9c231c1a099ed2ffecc
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

RHBDF1 DGKK ZBTB10 ADGRF1

9.07e-059511043d6b97576ce4e7a3e495cbc7246ea8c0b2a386f7
ToppCell5'-Adult-LymphNode-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS3 RTN4IP1 PTH1R SERAC1 CNTN1

9.13e-051831105d67454baf0cf791a743b51afd1cb25bfb5765385
ToppCell5'-Adult-LymphNode-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS3 RTN4IP1 PTH1R SERAC1 CNTN1

9.13e-051831105e49ac8314b6fe98426b1514ea68d646297b8bc0f
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

ANK3 SAMD12 MAGI3 ADGRF1 SLC6A14

9.37e-051841105369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISLR ACTN3 SVEP1 CNTN6 RSPO1

9.37e-0518411053bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC ISLR RSPO3 C7 CNTN1

9.37e-0518411054d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCelldroplet-Kidney-nan-21m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISLR ACTN3 SVEP1 CNTN6 RSPO1

9.61e-05185110533cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCellCOVID-19-Fibroblasts-Adventitial_FB|COVID-19 / group, cell type (main and fine annotations)

BOC DPYSL3 SVEP1 RSPO3 C7

9.61e-051851105a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISLR ACTN3 SVEP1 CNTN6 RSPO1

9.61e-0518511059954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC DPYSL3 ISLR SVEP1 C7

9.61e-051851105eaa54b76743628c89b4310be57b87fa92b75fd37
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC DPYSL3 ISLR SVEP1 C7

9.61e-051851105f7f4c921d248c637351e2e882589b99ba7f04b66
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC DPYSL3 ISLR SVEP1 C7

9.61e-051851105ff38a15af3dec36d9993f06623591872b5d1da9a
ToppCellMesenchymal_cells-Osteo-CAR|World / Lineage and Cell class

DPYSL3 GDPD2 ISLR PTH1R RSPO3

9.61e-05185110516f1588893d09c864e0cb4f837a1b972a1a57baa
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SPAM1 TOPAZ1 MPEG1 SCN10A SIGLEC11

9.86e-05186110523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK3 SAMD12 ELF3 ADGRF1 SLC6A14

9.86e-051861105acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellMesenchymal_cells-Adipo-CAR|World / Lineage and Cell class

GDPD2 ISLR PTH1R SVEP1 RSPO3

9.86e-0518611056ca8ce7ced91d6308b7c056032ffec1b37c974bf
ToppCellfacs-Pancreas-Exocrine-24m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISLR SVEP1 RSPO3 TSPAN4 C7

1.01e-0418711050f90bce2087aecfdbb377e6f46c6e468efbb6e28
ToppCellfacs-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISLR SVEP1 RSPO3 TSPAN4 C7

1.01e-04187110576c957b2976d38adb45e07bcf96c689442e1fc20
ToppCellfacs-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISLR SVEP1 RSPO3 TSPAN4 C7

1.01e-04187110590a1078b0303799fba5d2ca4fa12076fd75b78b1
ToppCellControl-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

ADAMTS3 BDKRB2 RASA4 RASA4B C7

1.01e-0418711055429ae85942b8ec3895cceb63c663de3c24ca064
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 MAGI3 UBR5 ARID2 PHACTR4

1.04e-0418811056468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 MAGI3 UBR5 ARID2 PHACTR4

1.04e-0418811057a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 MAGI3 UBR5 ARID2 PHACTR4

1.04e-0418811059cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

BOC DPYSL3 ADAMTS3 SVEP1 C7

1.04e-041881105706a26c372add839d947749f0521a0e1f5c9b0ec
Diseasefocal segmental glomerulosclerosis 1 (implicated_via_orthology)

ACTN4 ACTN3

1.15e-0451012DOID:0111128 (implicated_via_orthology)
Diseasehelix rolling

SULT1C4 FECH

3.20e-0481012EFO_0007670
Diseasetriglycerides in medium VLDL measurement

TDRD15 DNAH10 RSPO3

8.97e-04551013EFO_0022155
Diseaseesterified cholesterol measurement, low density lipoprotein cholesterol measurement

TDRD15 ADAMTS3

1.03e-03141012EFO_0004611, EFO_0008589
Diseasetriglycerides in small VLDL measurement

TDRD15 DNAH10 RSPO3

1.21e-03611013EFO_0022145
Diseasefree cholesterol in very large VLDL measurement

TDRD15 DNAH10 RSPO3

1.21e-03611013EFO_0022274
Diseasephospholipids in large VLDL measurement

TDRD15 DNAH10 RSPO3

1.27e-03621013EFO_0022169
Diseasephospholipids in very large VLDL measurement

TDRD15 DNAH10 RSPO3

1.27e-03621013EFO_0022299
Diseasecholesterol in large VLDL measurement

TDRD15 DNAH10 RSPO3

1.46e-03651013EFO_0021902
Diseasecholesterol in very large VLDL measurement

TDRD15 DNAH10 RSPO3

1.46e-03651013EFO_0022230
Diseasetotal lipids in small VLDL

TDRD15 DNAH10 RSPO3

1.59e-03671013EFO_0022148
Diseasetotal lipids in large VLDL

TDRD15 DNAH10 RSPO3

1.59e-03671013EFO_0022175
Diseasefree cholesterol in large VLDL measurement

TDRD15 DNAH10 RSPO3

1.66e-03681013EFO_0022265
Diseaseulcerative colitis, Crohn's disease

ADCY7 NOD2

2.12e-03201012EFO_0000384, EFO_0000729
Diseasebrain measurement, neuroimaging measurement

DPYSL2 DPYSL3 ANK3 ADAMTS3 ACTN4 CRMP1 ACAD11

2.87e-035501017EFO_0004346, EFO_0004464
DiseaseAlbuminuria

PYCARD CD38

3.05e-03241012C0001925
DiseaseFEV change measurement, response to zileuton

PRORP LMBRD1

3.31e-03251012EFO_0005921, EFO_0007676

Protein segments in the cluster

PeptideGeneStartEntry
SWNTGRFTGCPSWKD

nan

46

Q6ZRU5
RFTGCPSWKDFWKPV

nan

51

Q6ZRU5
KLFSFTPAWNWTCKD

PYCARD

161

Q9ULZ3
IFLWCSGLKPQKGFW

FAM227B

286

Q96M60
KTLKDTSPGGQWWNF

EPHA1

656

P21709
TFAQSKCPQVEWLGW

BDKRB2

41

P30411
RQGKVWKAPSSWFID

BARD1

751

Q99728
DVCWLNWSNGSKPLL

ADGRF1

731

Q5T601
NDSSVCLDWEPWSKG

ADIG

46

Q0VDE8
PWSKGPAEFCWKGTL

ADIG

56

Q0VDE8
WSKNWAKAAAFVTSP

DPYSL3

291

Q14195
TFTCWLKLDKGFIWS

ADGRE4P

326

Q86SQ3
PAWEKQQRKTFTAWC

ACTN4

46

O43707
WQSCKKWFQTPSQVF

ARID2

1636

Q68CP9
FLWFTGDNGPWAQKC

ARSG

296

Q96EG1
KASWLGEQPQFWSKT

ELF3

56

P78545
KDLCAAAQVSWPWKF

ECT2L

96

Q008S8
WENCPLGWVKKKASG

SLC22A18AS

11

Q8N1D0
WTKAACAWEQVPFFL

ADCY7

116

P51828
KGNESFLWDCHAKPW

CD163L1

1316

Q9NR16
QLPCSDWANDFGKPW

CYB5D1

106

Q6P9G0
AFLGKPWSSWIDAAK

ATXN7L1

41

Q9ULK2
KWWSSGAGNPKCKIA

ACAD11

536

Q709F0
WRKDCSNNPVSVFWK

CD38

176

P28907
KEFIWCNKDWAIPGT

C16orf46

166

Q6P387
RTATVWKTLCPFWGE

RASA4

41

O43374
WKNKEWSSEDGEPCA

PCK1

386

P35558
VSCGWDKLVKVWNLA

RACK1

166

P63244
RTATVWKTLCPFWGE

RASA4B

41

C9J798
WAAAAWAKSGKPSGE

MPEG1

11

Q2M385
QAWCFPLKEASWKPV

KLHL30

346

Q0D2K2
INVDPCAKGWIDWAA

NDRG3

161

Q9UGV2
LGWGAFWNKSKSPLD

DGKK

586

Q5KSL6
SAWWCDNGITPTKNL

SPACA5

81

Q96QH8
WLSKVQECAVSWAGP

MAGI3

11

Q5TCQ9
GLKFPSVWDWSLQFT

MTMR10

531

Q9NXD2
WSKNWAKAAAFVTSP

DPYSL2

291

Q16555
KCNTSWVKENVGCPW

ERVFC1-1

131

P60608
NSWWTKFCGALRPLK

LMBRD1

291

Q9NUN5
PFDCTCGIVWLKTWA

ISLR

181

O14498
WKCAQETAWDFALPK

MICU1

461

Q9BPX6
WSGNCCFWKTEVLVK

GP2

141

P55259
WWQARKISDPATCAG

MPP4

286

Q96JB8
WTALQGGKPCLFWNE

KREMEN1

46

Q96MU8
NKPWLFSLLWCAGVD

GDPD2

451

Q9HCC8
AWWAAKVFANSCTLP

FMO6P

386

O60774
CFKNWDGSPVSSWIL

OAS1

331

P00973
CGTNVCRKPFSFKWW

PADI3

646

Q9ULW8
LNLNSWPCKSKEEWN

PHACTR4

561

Q8IZ21
WCSFNTADWVLPGKK

NCOA4

531

Q13772
GYPLPSWTWKKCSDK

FLT3

456

P36888
WSKNWAKAAAFVTSP

DPYSL4

291

O14531
TFEWALKSWSQCSKP

ADAMTS3

846

O15072
TFIPFCLWRAWSKQK

BOC

871

Q9BWV1
PQNDKPSKWWTCFVK

ARPC3

151

O15145
KPVWSKAFLLGEAAW

FRRS1

396

Q6ZNA5
ACCFPTFLIWLSKWQ

GPR148

176

Q8TDV2
APKPKFSWSKGTEWL

CNTN1

441

Q12860
WSSWSPCVQGKKTRS

C7

506

P10643
LWPDGSLGDWKSFSC

HYAL3

381

O43820
PWDKKVFRTWESSGA

ANK3

2846

Q12955
AKESQWDPTWLYLCK

ANKMY1

831

Q9P2S6
LWECKASGKPNPWYT

CNTN6

336

Q9UQ52
VRKEQCSFSWDWGPS

MANBA

181

O00462
DNDAKPWLWKFSNCF

MARF1

21

Q9Y4F3
WAWNAPSEFCLGKFD

SPAM1

51

P38567
CQPWRWKSGAAAAAV

FECH

31

P22830
KRKKPCAWLSDQGWE

DNAH10

3761

Q8IVF4
GKDSFRALKFPWVWT

SACS

1266

Q9NZJ4
RALKFPWVWTGKKFC

SACS

1271

Q9NZJ4
PWVWTGKKFCPLAQA

SACS

1276

Q9NZJ4
WSKNWAKAAAFVTSP

CRMP1

291

Q14194
ECWKNSSGPWLRADS

PCARE

1161

A6NGG8
TETWAPDFLKKWSGA

RTN4IP1

281

Q8WWV3
TTCWPKTWLAKDCPA

SERAC1

431

Q96JX3
WPLGKTWSQEAVSFF

TDRD6

606

O60522
PDKRTCHWGFESAKW

SKIL

311

P12757
QAVPCKWIWFENSKN

TDRD15

1636

B5MCY1
PKKETWVVGWIQACS

FAM78A

81

Q5JUQ0
KKKTVTGWWPCQVLD

FER1L5

1876

A0AVI2
WSGLCKLWSVPDCNL

PRPF4

251

O43172
CAVWKFGKQWQPTLL

TAF1C

316

Q15572
WPEDITKWPICTKNS

RHBDF1

566

Q96CC6
SEWSPWGPCSKKQQL

RSPO1

151

Q2MKA7
KWLGVWKTNPSVFFV

SHCBP1L

156

Q9BZQ2
SKPVALWTQQDVCKW

SAMD12

71

Q8N8I0
KGIPASLSWCWNAED

WDR17

126

Q8IZU2
WKPTYTTEWPDCAKK

SVEP1

776

Q4LDE5
WFESVPGKQWKGQFT

PRORP

326

O15091
PAWEKQQRKTFTAWC

ACTN3

41

Q08043
AAWNKEDFPWSGKVK

RECQL

66

P46063
CTPDSNIVKWFWKAV

SMURF2

646

Q9HAU4
ETKKVASPGWTCWEC

ZNF532

1016

Q9HCE3
AGSHNGEETWKWKPC

ZNF778

216

Q96MU6
GEETWKWKPCGKALT

ZNF778

221

Q96MU6
AAHCFWKNKDPTQWI

TMPRSS11F

246

Q6ZWK6
WKNKDPTQWIATFGA

TMPRSS11F

251

Q6ZWK6
TVWNKGTWACQKLIA

NOD2

91

Q9HC29
CWDLSSGNKKWIIQV

PTH1R

351

Q03431
CKLDTTKSPWDVGWQ

SCN10A

1126

Q9Y5Y9
TKSPWDVGWQVRKTC

SCN10A

1131

Q9Y5Y9
ESFPFWASKGKLEWQ

SPATA31D1

466

Q6ZQQ2
CTKAGTKPPSLQWAW

TECPR1

856

Q7Z6L1
TCDIWDKIWNFQAKP

SULT1C4

31

O75897
SEWNPWSPCTKKGKT

RSPO3

151

Q9BXY4
PFCWVTGWGKVKESS

PRSS48

146

Q7RTY5
RISAWCWKKASLPES

TOPAZ1

501

Q8N9V7
APGTWWKAPCYETVK

TSPAN4

181

O14817
LQCSFQTSWLKDFPW

ZBTB10

246

Q96DT7
SAPKNEWIGKNASSW

MID2

611

Q9UJV3
LPWKNCSSWSDKNCS

SLC6A14

151

Q9UN76
ACADWETPSKTKWSL

ZNF317

126

Q96PQ6
WAFKKCPAPSFSWTG

SIGLEC11

181

Q96RL6
WKCWVQSKYANGETS

ZMYM3

1071

Q14202
LWEQSFCWKSPIALG

ZRANB1

566

Q9UGI0
APLCWKAGEWVGFTL

TYSND1

281

Q2T9J0
QWWPDKDGTKFICIG

UBR5

361

O95071
SKAEGKRWCGSIPWQ

TTF2

81

Q9UNY4
KRWCGSIPWQDPDSK

TTF2

86

Q9UNY4
AFLKWICRWPTFGSA

MYO7B

1996

Q6PIF6