Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	RIBOSOMAL_S4E	RPS4Y2 RPS4Y1	6.27e-05	3	86	2	PS00528
Domain	40S_S4_C	RPS4Y2 RPS4Y1	6.27e-05	3	86	2	IPR032277
Domain	Ribosomal_S4e_N_CS	RPS4Y2 RPS4Y1	6.27e-05	3	86	2	IPR018199
Domain	RS4NT	RPS4Y2 RPS4Y1	6.27e-05	3	86	2	PF08071
Domain	Ribosomal_S4e_central_region	RPS4Y2 RPS4Y1	6.27e-05	3	86	2	IPR013845
Domain	Ribosomal_S4e_N	RPS4Y2 RPS4Y1	6.27e-05	3	86	2	IPR013843
Domain	Ribosomal_S4e_central	RPS4Y2 RPS4Y1	6.27e-05	3	86	2	PD002667
Domain	Ribosomal_S4e	RPS4Y2 RPS4Y1	6.27e-05	3	86	2	IPR000876
Domain	Ribosomal_S4e	RPS4Y2 RPS4Y1	6.27e-05	3	86	2	PF00900
Domain	Neuregulin_C	NRG1 NRG2	6.27e-05	3	86	2	IPR002154
Domain	40S_S4_C	RPS4Y2 RPS4Y1	6.27e-05	3	86	2	PF16121
Domain	Neuregulin	NRG1 NRG2	6.27e-05	3	86	2	PF02158
Domain	S4	RPS4Y2 RPS4Y1	2.08e-04	5	86	2	PS50889
Domain	S4	RPS4Y2 RPS4Y1	2.08e-04	5	86	2	SM00363
Domain	S4_RNA-bd	RPS4Y2 RPS4Y1	3.11e-04	6	86	2	IPR002942
Domain	ARM-type_fold	PIK3CB MROH2A AP3B2 UBR4 USP24 UTP20 ECPAS	9.61e-04	339	86	7	IPR016024
Domain	KOW	RPS4Y2 RPS4Y1	1.12e-03	11	86	2	IPR005824
Domain	KOW	RPS4Y2 RPS4Y1	1.12e-03	11	86	2	PF00467
Domain	-	RAG2 KBTBD8 KLHL32	1.40e-03	48	86	3	2.120.10.80
Domain	Kelch-typ_b-propeller	RAG2 KBTBD8 KLHL32	2.08e-03	55	86	3	IPR015915
Domain	Frizzled/SFRP	FZD6 FRZB	2.41e-03	16	86	2	IPR015526
Domain	FRI	FZD6 FRZB	3.77e-03	20	86	2	SM00063
Domain	HEAT_REPEAT	MROH2A UTP20 ECPAS	4.13e-03	70	86	3	PS50077
Domain	-	FZD6 FRZB	4.16e-03	21	86	2	1.10.2000.10
Domain	Frizzled_dom	FZD6 FRZB	5.42e-03	24	86	2	IPR020067
Domain	tRNA-bd_arm	DSP CEP152	5.42e-03	24	86	2	IPR010978
Domain	FZ	FZD6 FRZB	5.42e-03	24	86	2	PS50038
Domain	Fz	FZD6 FRZB	5.42e-03	24	86	2	PF01392
Domain	T_SNARE	STX4 UACA	6.34e-03	26	86	2	PS50192
Pathway	KEGG_MEDICUS_REFERENCE_NRG_ERBB4_PI3K_SIGNALING_PATHWAY	NRG1 PIK3CB NRG2	1.88e-05	11	70	3	M47756
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ABCC4 ARRB1 TTLL3 MAOA UACA SCAF8 KIZ TBK1 CD2AP DPYSL5 IFT122 QSER1 ECPAS GNL3 TMEM63A FARP2	1.26e-06	1489	90	16	28611215
Pubmed	Cloning and localization of the murine Xpct gene: evidence for complex rearrangements during the evolution of the region around the Xist gene.	RPS4Y2 RPS4Y1 NAP1L2	1.39e-06	9	90	3	9545634
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	DSP KIZ TBK1 CD2AP DPYSL5 CEP152 LYAR CCDC77 ECPAS GNL3 CFAP97 ASAP1	2.08e-06	853	90	12	28718761
Pubmed	Bioactive recombinant neuregulin-1, -2, and -3 expressed in Escherichia coli.	NRG1 NRG2	6.62e-06	2	90	2	15039062
Pubmed	Ubiquitin-specific protease 24 promotes EV71 infection by restricting K63-linked polyubiquitination of TBK1.	TBK1 USP24	6.62e-06	2	90	2	36334706
Pubmed	NRG1 and NRG2 fusion positive solid tumor malignancies: a paradigm of ligand-fusion oncogenesis.	NRG1 NRG2	6.62e-06	2	90	2	34996744
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	DSP TBK1 CD2AP UBR4 USP24 KDM2B ZDBF2 ECPAS	1.34e-05	418	90	8	34709266
Pubmed	Cancer-associated splicing variants of the CDCA1 and MSMB genes expressed in cancer cell lines and surgically resected gastric cancer tissues.	NUF2 MSMB	1.98e-05	3	90	2	19081476
Pubmed	Inactivation of the Rps4 gene on the mouse X chromosome.	RPS4Y2 RPS4Y1	1.98e-05	3	90	2	1783379
Pubmed	Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome.	RPS4Y2 RPS4Y1	1.98e-05	3	90	2	2124517
Pubmed	Expression level of Rps4 mRNA in 39,X mice and 40,XX mice.	RPS4Y2 RPS4Y1	1.98e-05	3	90	2	8187552
Pubmed	Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction.	RPS4Y2 RPS4Y1	1.98e-05	3	90	2	22708584
Pubmed	Modular and Distinct Plexin-A4/FARP2/Rac1 Signaling Controls Dendrite Morphogenesis.	PLXNA4 FARP2	1.98e-05	3	90	2	32499377
Pubmed	Relationship between the monosomy X phenotype and Y-linked ribosomal protein S4 (Rps4) in several species of mammals: a molecular evolutionary analysis of Rps4 homologs.	RPS4Y2 RPS4Y1	1.98e-05	3	90	2	8808278
Pubmed	The role of neuregulin-ErbB4 interactions on the proliferation and organization of cells in the subventricular zone.	NRG1 NRG2	1.98e-05	3	90	2	16446434
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ARRB1 UACA SCAF8 MORF4L1 CD2AP APTX KDM2B RPS17 UTP20 APOH LYAR DICER1 GNL3 FARP2	2.98e-05	1497	90	14	31527615
Pubmed	Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1.	PIK3CB CD2AP ASAP1	3.70e-05	25	90	3	12029088
Pubmed	Interactions among genes in the ErbB-Neuregulin signalling network are associated with increased susceptibility to schizophrenia.	NRG1 NRG2	3.96e-05	4	90	2	17598910
Pubmed	Structure and function of ribosomal protein S4 genes on the human and mouse sex chromosomes.	RPS4Y2 RPS4Y1	3.96e-05	4	90	2	8139551
Pubmed	Homeostatic proliferation of naïve CD8+ T cells depends on CD62L/L-selectin-mediated homing to peripheral LN.	SELL RAG2	3.96e-05	4	90	2	19658092
Pubmed	Tumor-induced MDSC act via remote control to inhibit L-selectin-dependent adaptive immunity in lymph nodes.	SELL RAG2	3.96e-05	4	90	2	27929373
Pubmed	Phosphoinositide 3-kinase β mediates microvascular endothelial repair of thrombotic microangiopathy.	RAG2 PIK3CB	3.96e-05	4	90	2	25139353
Pubmed	The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development.	RAG2 PIK3CB	3.96e-05	4	90	2	20699475
Pubmed	Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases.	NRG1 NRG2	3.96e-05	4	90	2	9168115
Pubmed	A Japanese-specific allele in the GALNT11 gene.	ABCC4 CEP152	6.59e-05	5	90	2	20547088
Pubmed	Use of a reverse transcriptase-polymerase chain reaction assay to analyze allele-specific expression in individual hippocampal neurons.	RPS4Y2 RPS4Y1	6.59e-05	5	90	2	9562962
Pubmed	The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease.	RAG2 DICER1	6.59e-05	5	90	2	18725527
Pubmed	A novel model for lymphocytic infiltration of the thyroid gland generated by transgenic expression of the CC chemokine CCL21.	SELL RAG2	6.59e-05	5	90	2	15470018
Pubmed	Mislocalization or reduced expression of Arf GTPase-activating protein ASAP1 inhibits cell spreading and migration by influencing Arf1 GTPase cycling.	CD2AP ASAP1	6.59e-05	5	90	2	15632162
Pubmed	Septin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking.	STX4 CD2AP	6.59e-05	5	90	2	22809625
Pubmed	Maintenance of X inactivation of the Rps4, Zfx, and Ube1 genes in a mouse in vitro system.	RPS4Y2 RPS4Y1	6.59e-05	5	90	2	7681608
Pubmed	Ligands for ErbB-family receptors encoded by a neuregulin-like gene.	NRG1 NRG2	6.59e-05	5	90	2	9168114
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	RPS4Y2 FAM184B ARRB1 DSP RPS4Y1 GNA13 UBR4 PLXNA4 RPS17 IFT122 OR10G9 CCDC77 OR10G4	8.54e-05	1442	90	13	35575683
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	APPBP2 ACOT11 SCAF8 RABGAP1L PCDH10 KLHL32 ASAP1	9.26e-05	407	90	7	12693553
Pubmed	Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.	MORF4L1 TBK1 CEP152 LYAR DICER1 GNL3	9.67e-05	283	90	6	21903422
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	APPBP2 DSP TBK1 UBR4 PLXNA4 UTP20 SYNC ECPAS PCDH10	1.24e-04	736	90	9	29676528
Pubmed	Proximity Mapping of CCP6 Reveals Its Association with Centrosome Organization and Cilium Assembly.	CEP152 CCDC77 FARP2	1.32e-04	38	90	3	36674791
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	NRG1 EXOC5 DSP SCAF8 MORF4L1 USP24 NUF2 NIBAN2	1.36e-04	582	90	8	20467437
Pubmed	An evaluation of the inactive mouse X chromosome in somatic cell hybrids.	RPS4Y2 RPS4Y1	1.38e-04	7	90	2	8460399
Pubmed	Embryonic growth and the evolution of the mammalian Y chromosome. II. Suppression of selfish Y-linked growth factors may explain escape from X-inactivation and rapid evolution of Sry.	RPS4Y2 RPS4Y1	1.38e-04	7	90	2	7928394
Pubmed	Proximity interactions among centrosome components identify regulators of centriole duplication.	KIZ CCDC15 CEP152 LYAR	1.41e-04	101	90	4	24613305
Pubmed	TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.	EXOC5 DSP MORF4L1 RPS17 LYAR GNL3	1.79e-04	317	90	6	30997501
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	UACA DSP SCAF8 USP24 SENP6 KDM2B UTP20 NIBAN2 ECPAS	1.81e-04	774	90	9	15302935
Pubmed	Embryo-uterine interactions via the neuregulin family of growth factors during implantation in the mouse.	NRG1 NRG2	1.84e-04	8	90	2	15306553
Pubmed	Physical mapping of 2000 kb of the mouse X chromosome in the vicinity of the Xist locus.	RPS4Y2 RPS4Y1	1.84e-04	8	90	2	8468051
Pubmed	Dynamic expression of Erbb pathway members during early mammary gland morphogenesis.	NRG1 NRG2	1.84e-04	8	90	2	17960183
Pubmed	Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study.	UTP20 LRRC18	1.84e-04	8	90	2	17903303
Pubmed	Differential expression of neuregulins and their receptors in the olfactory bulb layers of the developing mouse.	NRG1 NRG2	1.84e-04	8	90	2	16488402
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	UACA DSP UTP20 ECPAS DICER1	1.85e-04	202	90	5	33005030
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	ARRB1 UACA KIZ CD2AP CHEK2 CCDC15 CEP152 NUF2 NIBAN2 GNL3 CFAP97	1.96e-04	1155	90	11	20360068
Pubmed	Defining the membrane proteome of NK cells.	ABCC4 RPS4Y1 GNA13 UBR4 RPS17 PANX1 IFT122 NUF2 CCDC77 ECPAS GNL3	2.15e-04	1168	90	11	19946888
Pubmed	FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.	GNA13 MORF4L1 UTP20 NIBAN2 LYAR	2.32e-04	212	90	5	33462405
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	MORF4L1 SENP6 KDM2B RPS17 ZDBF2 GNL3	2.57e-04	339	90	6	30415952
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	CMBL ARRB1 DSP SCAF8 MORF4L1 UBR4 USP24 RPS17 LYAR WARS2 GNL3 SPINK5	2.87e-04	1415	90	12	28515276
Pubmed	Tetraspanin 6 (TSPAN6) negatively regulates retinoic acid-inducible gene I-like receptor-mediated immune signaling in a ubiquitination-dependent manner.	PLAAT4 TBK1	2.94e-04	10	90	2	22908223
Pubmed	The ubiquitin-specific protease USP8 is critical for the development and homeostasis of T cells.	SELL RAG2	2.94e-04	10	90	2	26214742
Pubmed	ErbB/HER ligands in human breast cancer, and relationships with their receptors, the bio-pathological features and prognosis.	NRG1 NRG2	2.94e-04	10	90	2	17962208
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	APPBP2 DSP RPS17 UTP20 LYAR DICER1 GNL3 ASAP1	3.03e-04	655	90	8	35819319
Pubmed	Expression of Wnt signalling pathway genes during tooth development.	FZD6 FRZB	3.59e-04	11	90	2	10415363
Pubmed	The Onecut transcription factor HNF-6 regulates in motor neurons the formation of the neuromuscular junctions.	NRG1 NRG2	3.59e-04	11	90	2	23227180
Pubmed	The nuclear transcription factor RARalpha associates with neuronal RNA granules and suppresses translation.	RPS4Y2 RPS4Y1 RPS17	3.78e-04	54	90	3	18495661
Pubmed	Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.	RABGAP1L UBR4 TMEM63A	4.21e-04	56	90	3	9455484
Pubmed	A Cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeleton.	CD2AP ASAP1	4.30e-04	12	90	2	12672817
Pubmed	Epithelial Wnt/β-catenin signaling regulates palatal shelf fusion through regulation of Tgfβ3 expression.	FZD6 FRZB	4.30e-04	12	90	2	21185284
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ABCA5 SENP6 KDM2B ECPAS DICER1 CFAP97 TIAM2	4.56e-04	529	90	7	14621295
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	FAM184B TTLL3 CD2AP KBTBD8 QSER1 CCDC77 KLHL32 LRRC18 TIAM2 ASAP1	4.98e-04	1084	90	10	11544199
Pubmed	Rps4 maps near the inactivation center on the mouse X chromosome.	RPS4Y2 RPS4Y1	5.07e-04	13	90	2	1740345
Pubmed	XIST and the mapping of the X chromosome inactivation centre.	RPS4Y2 RPS4Y1	5.07e-04	13	90	2	1772416
Pubmed	A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.	KDM2B CEP152 ECPAS	5.15e-04	60	90	3	20682791
Pubmed	Cell-fate determination by ubiquitin-dependent regulation of translation.	ARRB1 KBTBD8	5.91e-04	14	90	2	26399832
Pubmed	Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway.	PIK3CB DICER1	5.91e-04	14	90	2	18988856
Pubmed	Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.	STX4 SCAF8 MORF4L1 RPS17 NIBAN2 GNL3	6.40e-04	403	90	6	35253629
Pubmed	Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions.	ARRB1 KBTBD8	6.80e-04	15	90	2	29999490
Pubmed	The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.	EXOC5 TBK1	6.80e-04	15	90	2	24056301
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	FZD6 NRG1 STX4 UACA PANX1 NIBAN2 FARP2	7.00e-04	569	90	7	30639242
Pubmed	Repression of rRNA transcription by PARIS contributes to Parkinson's disease.	RPS4Y2 RPS4Y1 RPS17 LYAR GNL3	7.21e-04	272	90	5	25315684
Pubmed	Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.	DSP TBK1 DICER1 FARP2	9.50e-04	167	90	4	25659891
Pubmed	Identification of a Pax6-dependent epidermal growth factor family signaling source at the lateral edge of the embryonic cerebral cortex.	NRG1 NRG2	1.10e-03	19	90	2	12878679
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	UACA DSP TBK1 CD2AP RPS17 LYAR ECPAS GNL3	1.20e-03	809	90	8	32129710
Pubmed	Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome.	RPS4Y2 RPS4Y1	1.22e-03	20	90	2	16635246
Pubmed	The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization.	PIK3CB CD2AP ASAP1	1.24e-03	81	90	3	20697350
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	CMBL ZNF486 UACA DSP ACOT11 CD2AP NIBAN2 TIAM2 TMEM63A	1.27e-03	1016	90	9	19056867
Pubmed	Structure of the human 80S ribosome.	RPS4Y2 RPS4Y1 RPS17	1.28e-03	82	90	3	25901680
Pubmed	A male germ-cell-specific ribosome controls male fertility.	RPS4Y2 RPS4Y1 RPS17	1.42e-03	85	90	3	36517592
Pubmed	Characterization of Wnt signaling components and activation of the Wnt canonical pathway in the murine retina.	FZD6 FRZB	1.48e-03	22	90	2	12815618
Pubmed	Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.	ABCC4 ABCA5	1.48e-03	22	90	2	8894702
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	DSP UBR4 USP24 UTP20 ECPAS DICER1 GNL3	1.55e-03	653	90	7	22586326
Pubmed	A novel role for cilia-dependent sonic hedgehog signaling during submandibular gland development.	NRG1 NRG2	1.62e-03	23	90	2	29532549
Pubmed	Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism.	RPS4Y2 RPS4Y1 RPS17 GNL3	1.74e-03	197	90	4	32434143
Pubmed	Exploring the link between MORF4L1 and risk of breast cancer.	MORF4L1 CHEK2	1.76e-03	24	90	2	21466675
Pubmed	A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.	FZD6 FRZB	1.76e-03	24	90	2	9096311
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ARRB1 DSP MORF4L1 UBR4 NAP1L2 CCDC15 SENP6 IFT122 SYNC ZNF583	1.80e-03	1285	90	10	35914814
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	UACA DSP MORF4L1 TBK1 GNL3 ASAP1	1.87e-03	497	90	6	23414517
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	CMBL EXOC5 AP3B2 UBR4 USP24 ECPAS	1.89e-03	498	90	6	36634849
Pubmed	NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy.	DSP TBK1	1.91e-03	25	90	2	30309841
Pubmed	A role for Wnt/beta-catenin signaling in lens epithelial differentiation.	FZD6 FRZB	1.91e-03	25	90	2	12812787
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR51F2 OR4F21 OR10G9 OR10G4 OR52E2	1.93e-03	340	90	5	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR51F2 OR4F21 OR10G9 OR10G4 OR52E2	1.93e-03	340	90	5	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR51F2 OR4F21 OR10G9 OR10G4 OR52E2	2.01e-03	343	90	5	32295537
Pubmed	Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning.	RPS4Y2 RPS4Y1 RPS17	2.01e-03	96	90	3	21529712
Cytoband	17q24.3	ABCA5 GNA13	5.07e-04	17	90	2	17q24.3
Cytoband	Ensembl 112 genes in cytogenetic band chr17q24	ABCA5 GNA13 APOH	9.69e-04	98	90	3	chr17q24
Cytoband	12q14.1	TBK1 CAPS2	1.39e-03	28	90	2	12q14.1
Cytoband	11q24.1	OR10G9 OR10G4	2.42e-03	37	90	2	11q24.1
GeneFamily	S ribosomal proteins	RPS4Y2 RPS4Y1 RPS17	1.49e-04	34	55	3	728
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#1_top-relative-expression-ranked_1000	RPS4Y2 ABCC4 PIK3CB AP3B2 KBTBD8 CHEK2 UTP20 NUF2 LYAR GNL3	8.92e-07	334	85	10	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k1_1000
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_500	RPS4Y2 PIK3CB AP3B2 KBTBD8 CHEK2 UTP20	2.28e-05	142	85	6	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k3_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	NRG1 PIK3CB KIZ ICE2 KBTBD8 DPYSL5 CCDC15 UTP20 ZDBF2 APOH LYAR KLHL32 DICER1 GNL3	3.57e-05	989	85	14	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2	ICE2 TBK1 USP24 CHEK2 NUF2 QSER1 APOH LYAR ECPAS DICER1	8.45e-05	564	85	10	Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
ToppCell	Bronchial_Biopsy\|World / Tissue, Lineage and Cell class of Lung Cells from 10X	UACA DSP BEND5 ACOT11 RPS4Y1 SPINK5	3.08e-06	198	90	6	f5b7013045b61fc56894f80092f799770dde1c8f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAM184B ABCC4 ABCA5 DSP NEURL1	2.07e-05	164	90	5	83141be8dfed85511ea6afda7c76ff4b6b5ef021
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACOT11 FRZB NEURL1 DPYSL5 KLHL32	2.75e-05	174	90	5	c529f3674b784f872f4387ffdeb46aecb619976b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAM184B ABCC4 PLAAT4 ABCA5 NEURL1	2.99e-05	177	90	5	8e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TTLL3 AP3B2 CEP152 ZDBF2 ZNF654	2.99e-05	177	90	5	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA5 ACOT11 FRZB KLHL32 FARP2	3.07e-05	178	90	5	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	IIH-CD8-CD4_Treg\|IIH / Condition, Cell_class and T cell subcluster	CMBL NEURL1 CEP152 IFT122 ECPAS	3.24e-05	180	90	5	d1a8b25115c80e5a5bd0b8244167a98250ab9778
ToppCell	normal_Lung-Myeloid_cells-CD207+CD1a+_LCs\|normal_Lung / Location, Cell class and cell subclass	ABCC4 DSP KBTBD8 PCDH10 TIAM2	3.32e-05	181	90	5	b55dbcfae8c92d322071906831489830a22239b9
ToppCell	COVID-19_Mild-CD4+_T_activated\|COVID-19_Mild / Disease condition and Cell class	SELL ICE2 RPS17 ECPAS CFAP97	3.41e-05	182	90	5	877b6e611626628e709568747512f2827ebb2795
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-basal_proximal\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NRG1 DSP MROH2A FRZB SPINK5	3.59e-05	184	90	5	575de705053da8b289670b5c40c1627c0833b5ed
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	UACA BEND5 USP24 ZDBF2 FARP2	3.98e-05	188	90	5	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	UACA BEND5 USP24 ZDBF2 FARP2	3.98e-05	188	90	5	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	UACA BEND5 USP24 ZDBF2 FARP2	3.98e-05	188	90	5	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MAOA FRZB CHEK2 NIBAN2 ZNF654	4.40e-05	192	90	5	0b954a4e5857dac45d97c491af9b27cb2d1bd339
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-basal_intermediate_\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FZD6 NRG1 DSP FRZB SPINK5	4.51e-05	193	90	5	83d2dd823808a2b5ca1a6889eefb541ec042b24c
ToppCell	distal-Hematologic-CD4+_Memory/Effector_T-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELL FAM184B RPS4Y1 NRG2 TIAM2	4.51e-05	193	90	5	58651c32820f268098d8979937397786d18bd0a1
ToppCell	(0)_NK/T_cells-(0)_T_CD4\|(0)_NK/T_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	SELL MAOA DSP RPS4Y1 RPS17	5.22e-05	199	90	5	a4bffbb9587829f0f52716d6939315a1aa1ae9b3
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SELL PLAAT4 RPS4Y1 RPS17 LYAR	5.34e-05	200	90	5	4f1855a9d96ac7c7ad62a709b265f9bd557b04fa
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	ABCA5 KDM2B ZNF654 WARS2 TMEM63A	5.34e-05	200	90	5	6b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SELL PLAAT4 RPS4Y1 RPS17 LYAR	5.34e-05	200	90	5	ab3223c5ab13cdfae0eb441051024151c2194744
Disease	thrombosis (implicated_via_orthology)	PIK3CB APOH	3.30e-04	10	81	2	DOID:0060903 (implicated_via_orthology)
Disease	fructose measurement	NRG1 UBR4	5.69e-04	13	81	2	EFO_0010477
Disease	obstructive sleep apnea	NRG1 CCDC77 WARS2	8.05e-04	66	81	3	EFO_0003918
Disease	major depressive disorder (is_marker_for)	NRG1 ARRB1	9.85e-04	17	81	2	DOID:1470 (is_marker_for)
Disease	squamous cell lung carcinoma	MORF4L1 CHEK2 PANX1 ECPAS	1.12e-03	165	81	4	EFO_0000708
Disease	partial thromboplastin time	NRG1 APOH	1.98e-03	24	81	2	EFO_0004310
Disease	airway responsiveness measurement	ABCC4 USP24	1.98e-03	24	81	2	EFO_0006897
Disease	pulmonary embolism	ABCC4 DNAH17	2.14e-03	25	81	2	EFO_0003827

Protein segments in the cluster

Peptide	Gene	Start	Entry
TKTVKKAARVIIEKY	RPS17	6	P08708
VKKVATKYISFCVKK	ABCA5	1311	Q8WWZ7
IAQRLSKVNKYICEK	BEND5	386	Q7L4P6
LRGQYIKAVKKIKCD	CEP152	1266	O94986
KASCKVPVKKATVVY	APOH	261	P02749
TNVKKSIRKKYCKVS	CFAP97	156	Q9P2B7
KCKLKYQQCKTEIKE	CAPS2	131	Q9BXY5
LKAECNKGYVKVKQV	APTX	61	Q7Z2E3
QYRVQCKKKEDKIGK	CCDC77	316	Q9BR77
KKIRLDRKYIVSCKQ	ACOT11	356	Q8WXI4
CVVKREFKKAEQLIK	APPBP2	256	Q92624
KKTKKRQCKVLFEYI	CD2AP	106	Q9Y5K6
LAFERKTCKKVAIKI	CHEK2	236	O96017
LKTYKAIEKILRNKC	DICER1	576	Q9UPY3
KTVKKIKISVRQYAD	ARRB1	226	P49407
NVACKNIEVKKLVYV	AP3B2	81	Q13367
KIYVMSIVCKNNKKV	RAG2	106	P55895
VKVKYRVLALKKLQT	NAP1L2	106	Q9ULW6
ENANKKEYVRVCSKK	QSER1	1431	Q2KHR3
CKSIQRVLERVLKKY	NIBAN2	466	Q96TA1
VVAYCKTKKQRKKLH	NRG1	261	Q02297
YEAKCVKVAIKDKQV	MORF4L1	26	Q9UBU8
KEIRKKKICELYAKV	MAOA	366	P21397
VIYGVRTKQIYKCVK	OR52E2	291	Q8NGJ4
RTKQIYKCVKKILLQ	OR52E2	296	Q8NGJ4
VYTLRNKEVKKAVLK	OR10G4	286	Q8NGN3
AAIKRVCKQLVIYKK	OR4F21	296	O95013
KCKELVKKIAIYRNR	IFT122	386	Q9HBG6
KTKVKREIVKLCSQY	SPINK5	286	Q9NQ38
VKMCKKIAQLTKVIY	FAM184B	36	Q9ULE4
LKECSKENVKYKIVA	ECPAS	1621	Q5VYK3
TKEQVYTSKLVRLCK	PLXNA4	271	Q9HCM2
YSVKIKQIQKAIIKV	OR51F2	306	Q8NH61
VKQYKRTVIEDCNKV	NUF2	366	Q9BZD4
TIDKQICTNKYKEKI	FAM214A	646	Q32MH5
IVCVVAYCKTKKQRK	NRG2	421	O14511
KKITLKVARNCIKIT	LRRC18	11	Q8N456
NKKNKEDCVEIYIKR	SELL	121	P14151
KCLSREKTYVKRLVK	GNA13	36	Q14344
LAVRCQKEKKLNIYT	PCDH10	736	Q9P2E7
EVKSYKCLKVLENIK	PANX1	341	Q96RD7
VAKLIYLCKEKKKTE	TMEM63A	266	O94886
QSDTCRVKLKYVKLK	KIZ	46	Q2M2Z5
RIFKKEDCKYIVVEK	MSMB	86	P08118
IKKTTAIIAEYKQIC	RABGAP1L	101	B7ZAP0
SKEYIRKKFLCVTKE	KBTBD8	171	Q8NFY9
KERYEKVIKACALKK	ABCC4	501	O15439
RKLCEKVYSDCKKLI	FZD6	96	O60353
CVKVCAYVRKQVEKI	EXOC5	576	O00471
EKILRACIEQVKKYS	ICE2	176	Q659A1
AEKQKKKTVIYTKCF	KDM2B	21	Q8NHM5
VKCVQDAIRAKKKAF	DNAH17	1916	Q9UFH2
VTKKKVSYVQLKERC	DSP	2176	P15924
KNKVRRVKTIYDCQA	ASAP1	1066	Q9ULH1
EITIKKLRKKVLAQY	LYAR	326	Q9NX58
SKKLYCQELKKVIEA	GNL3	126	Q9BVP2
TKRCKKLEAVYKEFE	FARP2	651	O94887
SVEKFIQKCKPEYKV	SCAF8	46	Q9UPN6
VYKKLVQREKTLKVR	DPYSL5	471	Q9BPU6
VYTLRNKEVKKAVLK	OR10G9	286	Q8NGN4
VYTLKKLQAKCAVLE	NAP1L6P	51	A6NFF2
AAIKRVCKQLVIYKR	OR4F3;	296	Q6IEY1
KVKQYRKVLLEKCLG	MROH2A	1421	A6NES4
KAKELAYTVCQEVKK	WARS2	341	Q9UGM6
LVKQKLFKVTKECVA	SYNC	241	Q9H7C4
VNCFKCVTILVKKVK	UTP20	2181	O75691
CVTILVKKVKSYQIT	UTP20	2186	O75691
RYGKSRCKQVEKAKV	PLAAT4	121	Q9UL19
VEEAKYKLCKVRKIT	RPS4Y1	116	P22090
VEEAKYKLCKVRKIT	RPS4Y2	116	Q8TD47
QKKARKKKVLIAICV	STX4	266	Q12846
CFAVYAVLDKVKTKK	PIK3CB	401	P42338
IYLAVCVNAVLKKVK	SPATA9	156	Q9BWV2
REKITTNCYKFKIKD	ARNTL	396	O00327
KIEKIKKKREQECYA	CCDC15	801	Q0P6D6
TQKLKEHCKVEYQIK	CMBL	191	Q96DG6
RKGSANVVECKVYKK	ZNF714	86	Q96N38
FKRYQQCVQKAIKEK	TRIAP1	41	O43715
NIKKYKTCIRSKVAN	TCEANC	216	Q8N8B7
KRAVILVYKENCKLK	TIAM2	1356	Q8IVF5
LIYEQVRLKITKKQC	NEURL1	101	O76050
NYVIRAKVKEIKTKC	FRZB	196	Q92765
LLVKVKICQKTVKRY	TMEM115	246	Q12893
QCKETFKIINRKKDY	ZDBF2	1596	Q9HCK1
DNVYKKSVKRLRCGK	ZNF654	1081	Q8IZM8
KRNICSVKYSVKKIN	SENP6	851	Q9GZR1
NAKIYVERAVKQKKI	TTLL3	6	Q9Y4R7
KKELDTIQECIKVKY	UACA	971	Q9BZF9
VKEAIKRSYIIKCIE	USP24	586	Q9UPU5
KAKYCQLIKEVKEAK	ZBED9	246	Q6R2W3
RCKKYLSQKNVVEKL	UBR4	1566	Q5T4S7
KVYKGRCRNKIVAIK	TNNI3K	476	Q59H18
KDSYQKVILRKFEKC	ZNF486	101	Q96H40
KHRKVYVEKKLLKCN	ZNF583	201	Q96ND8
CIRNIEKTVKVYEKL	TBK1	471	Q9UHD2
GKKREVCKVKELRYF	KLHL32	296	Q96NJ5