Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	pituitary gonadotropin complex	CGB3 CGB7 CGB1	4.70e-06	8	93	3	GO:0061696
Domain	Glyco_hormone_CN	CGB3 CGB7 MUC5B CGB1	7.22e-07	15	92	4	IPR006208
Domain	Cys_knot	CGB3 CGB7 MUC5B CGB1	7.22e-07	15	92	4	PF00007
Domain	Gonadotropin_bsu_CS	CGB3 CGB7 CGB1	2.29e-06	6	92	3	IPR018245
Domain	Gonadotropin_bsu	CGB3 CGB7 CGB1	3.99e-06	7	92	3	IPR001545
Domain	GLYCO_HORMONE_BETA_2	CGB3 CGB7 CGB1	3.99e-06	7	92	3	PS00689
Domain	GHB	CGB3 CGB7 CGB1	3.99e-06	7	92	3	SM00068
Domain	GLYCO_HORMONE_BETA_1	CGB3 CGB7 CGB1	3.99e-06	7	92	3	PS00261
Domain	DUF2075	SLFN13 SLFN11	7.18e-05	3	92	2	IPR018647
Domain	DUF2075	SLFN13 SLFN11	7.18e-05	3	92	2	PF09848
Domain	HSR	SP100 SP140L	2.38e-04	5	92	2	PS51414
Domain	HSR	SP100 SP140L	2.38e-04	5	92	2	PF03172
Domain	HSR_dom	SP100 SP140L	2.38e-04	5	92	2	IPR004865
Domain	AlbA_2	SLFN13 SLFN11	4.96e-04	7	92	2	PF04326
Domain	Schlafen	SLFN13 SLFN11	4.96e-04	7	92	2	IPR029684
Domain	Schlafen_AAA_dom	SLFN13 SLFN11	4.96e-04	7	92	2	IPR007421
Domain	SAND_dom	SP100 SP140L	6.59e-04	8	92	2	IPR000770
Domain	SAND	SP100 SP140L	6.59e-04	8	92	2	PF01342
Domain	SAND	SP100 SP140L	6.59e-04	8	92	2	PS50864
Domain	SAND	SP100 SP140L	6.59e-04	8	92	2	SM00258
Domain	P-loop_NTPase	MYH7B MAGI3 RFC1 TRIP13 KIF20B MAGI2 NLRP14 MYH14 SLFN13 RECQL4 SLFN11 KIF17	9.12e-04	848	92	12	IPR027417
Domain	TIL	MUC5B SSPOP	1.53e-03	12	92	2	PF01826
Domain	-	SP100 SP140L	1.53e-03	12	92	2	3.10.390.10
Domain	SAND_dom-like	SP100 SP140L	1.53e-03	12	92	2	IPR010919
Domain	C8	MUC5B SSPOP	1.53e-03	12	92	2	PF08742
Domain	LRR_8	LRSAM1 LRRTM1 LRCH3 LRRC27 TLR5	1.57e-03	171	92	5	PF13855
Domain	WW	MAGI3 ARHGAP39 MAGI2	1.60e-03	47	92	3	PF00397
Domain	WW	MAGI3 ARHGAP39 MAGI2	1.70e-03	48	92	3	SM00456
Domain	Unchr_dom_Cys-rich	MUC5B SSPOP	1.81e-03	13	92	2	IPR014853
Domain	C8	MUC5B SSPOP	1.81e-03	13	92	2	SM00832
Domain	Leu-rich_rpt_typical-subtyp	LRSAM1 LRRTM1 LRCH3 LRRC27 TLR5	1.83e-03	177	92	5	IPR003591
Domain	LRR_TYP	LRSAM1 LRRTM1 LRCH3 LRRC27 TLR5	1.83e-03	177	92	5	SM00369
Domain	WW_DOMAIN_2	MAGI3 ARHGAP39 MAGI2	2.03e-03	51	92	3	PS50020
Domain	WW_DOMAIN_1	MAGI3 ARHGAP39 MAGI2	2.03e-03	51	92	3	PS01159
Domain	TIL_dom	MUC5B SSPOP	2.10e-03	14	92	2	IPR002919
Domain	WW_dom	MAGI3 ARHGAP39 MAGI2	2.15e-03	52	92	3	IPR001202
Domain	Leu-rich_rpt	LRSAM1 LRRTM1 LRCH3 NLRP14 LRRC27 TLR5	2.22e-03	271	92	6	IPR001611
Domain	Myosin_N	MYH7B MYH14	2.42e-03	15	92	2	PF02736
Domain	Myosin_N	MYH7B MYH14	2.42e-03	15	92	2	IPR004009
Domain	VWD	MUC5B SSPOP	2.75e-03	16	92	2	SM00216
Domain	Guanylate_kinase_CS	MAGI3 MAGI2	2.75e-03	16	92	2	IPR020590
Domain	VWF_type-D	MUC5B SSPOP	2.75e-03	16	92	2	IPR001846
Domain	VWFD	MUC5B SSPOP	2.75e-03	16	92	2	PS51233
Domain	VWD	MUC5B SSPOP	2.75e-03	16	92	2	PF00094
Domain	Myosin_tail_1	MYH7B MYH14	3.49e-03	18	92	2	PF01576
Domain	Myosin_tail	MYH7B MYH14	3.49e-03	18	92	2	IPR002928
Domain	CTCK_1	MUC5B SSPOP	3.49e-03	18	92	2	PS01185
Domain	VWC_out	MUC5B SSPOP	3.89e-03	19	92	2	SM00215
Domain	Myosin-like_IQ_dom	MYH7B MYH14	3.89e-03	19	92	2	IPR027401
Domain	-	MYH7B MYH14	3.89e-03	19	92	2	4.10.270.10
Domain	-	CGB3 CGB7 CGB1	4.41e-03	67	92	3	2.10.90.10
Domain	Cystine-knot_cytokine	CGB3 CGB7 CGB1	4.41e-03	67	92	3	IPR029034
Domain	LRR_1	LRSAM1 LRRTM1 LRCH3 LRRC27 TLR5	4.56e-03	219	92	5	PF00560
Pubmed	TLR5 mediates CD172α(+) intestinal lamina propria dendritic cell induction of Th17 cells.	SIRPB1 SIRPA TLR5	8.14e-08	4	96	3	26907705
Pubmed	Isolation and characterization of the human chorionic gonadotropin beta subunit (CG beta) gene cluster: regulation of transcriptionally active CG beta gene by cyclic AMP.	CGB3 CGB7 CGB1	2.03e-07	5	96	3	2468994
Pubmed	The beta subunit of human chorionic gonadotropin is encoded by multiple genes.	CGB3 CGB7 CGB1	4.05e-07	6	96	3	6194155
Pubmed	Identification of the transcriptionally active genes of the chorionic gonadotropin beta gene cluster in vivo.	CGB3 CGB7 CGB1	4.05e-07	6	96	3	1371113
Pubmed	The beta chorionic gonadotropin-beta luteinizing gene cluster maps to human chromosome 19.	CGB3 CGB7 CGB1	4.05e-07	6	96	3	6204923
Pubmed	The human genome contains seven genes for the beta-subunit of chorionic gonadotropin but only one gene for the beta-subunit of luteinizing hormone.	CGB3 CGB7 CGB1	4.05e-07	6	96	3	6319099
Pubmed	A map of the hCG beta-LH beta gene cluster.	CGB3 CGB7 CGB1	4.05e-07	6	96	3	2422163
Pubmed	Evolution of the genes for the beta subunits of human chorionic gonadotropin and luteinizing hormone.	CGB3 CGB7 CGB1	7.08e-07	7	96	3	6690982
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ILF2 SIRPB1 SIRPA LRRTM1 ARHGAP39 SLC1A2 VIRMA PGAM5 MAGI2 DZANK1 SBF1 JAKMIP1 UNC79	2.51e-06	963	96	13	28671696
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	ILF2 SPOUT1 POLE LRSAM1 RFC1 TRIP13 PGAM5 KIF20B TMEM33 NUP205 SBF1 MYH14 RECQL4 NCAPD2 PLK1	4.45e-06	1353	96	15	29467282
Pubmed	Site-specific N-glycosylation of human chorionic gonadotrophin--structural analysis of glycopeptides by one- and two-dimensional 1H NMR spectroscopy.	CGB3 CGB7	7.54e-06	2	96	2	1820200
Pubmed	The cDNA for the beta-subunit of human chorionic gonadotropin suggests evolution of a gene by readthrough into the 3'-untranslated region.	CGB3 CGB7	7.54e-06	2	96	2	6774259
Pubmed	Interplay of PIWI/Argonaute protein MIWI and kinesin KIF17b in chromatoid bodies of male germ cells.	PIWIL1 KIF17	7.54e-06	2	96	2	16787948
Pubmed	Mouse Slfn8 and Slfn9 genes complement human cells lacking SLFN11 during the replication stress response.	SLFN13 SLFN11	7.54e-06	2	96	2	37833372
Pubmed	Tumorigenesis and metastasis of neoplastic Kaposi's sarcoma cell line in immunodeficient mice blocked by a human pregnancy hormone.	CGB3 CGB7	7.54e-06	2	96	2	7723844
Pubmed	Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.	SLFN13 SLFN11	7.54e-06	2	96	2	29563550
Pubmed	SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis.	SIRPB1 SIRPA	2.26e-05	3	96	2	36202053
Pubmed	BRCA2 phosphorylated by PLK1 moves to the midbody to regulate cytokinesis mediated by nonmuscle myosin IIC.	MYH14 PLK1	2.26e-05	3	96	2	24448238
Pubmed	Src homology 2 domain-containing protein tyrosine phosphatase substrate 1 regulates the migration of Langerhans cells from the epidermis to draining lymph nodes.	SIRPB1 SIRPA	2.26e-05	3	96	2	15034021
Pubmed	Non-Hematopoietic and Hematopoietic SIRPα Signaling Differently Regulates Murine B Cell Maturation in Bone Marrow and Spleen.	SIRPB1 SIRPA	2.26e-05	3	96	2	26222253
Pubmed	Negative regulation of platelet clearance and of the macrophage phagocytic response by the transmembrane glycoprotein SHPS-1.	SIRPB1 SIRPA	2.26e-05	3	96	2	12167615
Pubmed	Signal regulatory protein alpha initiates cachexia through muscle to adipose tissue crosstalk.	SIRPB1 SIRPA	2.26e-05	3	96	2	31507080
Pubmed	Molecular cloning, characterization and expression of thyroid-stimulating hormone receptor in channel catfish.	CGB3 CGB1	2.26e-05	3	96	2	19523396
Pubmed	Fine-scale quantification of HCG beta gene transcription in human trophoblastic and non-malignant non-trophoblastic tissues.	CGB3 CGB1	2.26e-05	3	96	2	18048458
Pubmed	Involvement of signal regulatory protein α, a negative regulator of Toll-like receptor signaling, in impairing the MyD88-independent pathway and intracellular killing of Burkholderia pseudomallei-infected mouse macrophages.	SIRPB1 SIRPA	2.26e-05	3	96	2	22988019
Pubmed	Hypothermia-induced tyrosine phosphorylation of SIRPα in the brain.	SIRPB1 SIRPA	2.26e-05	3	96	2	22468987
Pubmed	Imaging of Glioblastoma Tumor-Associated Myeloid Cells Using Nanobodies Targeting Signal Regulatory Protein Alpha.	SIRPB1 SIRPA	2.26e-05	3	96	2	34917090
Pubmed	Effect of Serum Deprivation Stress on Signal Induction Regulatory Protein-Alpha (SIRP-Alpha)-Mediated Erythrophagocytosis by Macrophages.	SIRPB1 SIRPA	2.26e-05	3	96	2	30894504
Pubmed	Inhibitory regulation of osteoclast bone resorption by signal regulatory protein alpha.	SIRPB1 SIRPA	2.26e-05	3	96	2	19667119
Pubmed	SIRPA-Inhibited, Marrow-Derived Macrophages Engorge, Accumulate, and Differentiate in Antibody-Targeted Regression of Solid Tumors.	SIRPB1 SIRPA	2.26e-05	3	96	2	28669759
Pubmed	SIRPα controls the activity of the phagocyte NADPH oxidase by restricting the expression of gp91(phox).	SIRPB1 SIRPA	2.26e-05	3	96	2	23022485
Pubmed	Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity.	SIRPB1 SIRPA	2.26e-05	3	96	2	29158380
Pubmed	Lack of non-hematopoietic SIRPα signaling disturbs the splenic marginal zone architecture resulting in accumulation and displacement of marginal zone B cells.	SIRPB1 SIRPA	2.26e-05	3	96	2	25817792
Pubmed	Critical role for protein tyrosine phosphatase SHP-1 in controlling infection of central nervous system glia and demyelination by Theiler's murine encephalomyelitis virus.	SIRPB1 SIRPA	2.26e-05	3	96	2	12134038
Pubmed	Central nervous system antigen P84 can serve as a substrate for neurite outgrowth.	SIRPB1 SIRPA	2.26e-05	3	96	2	2303162
Pubmed	SHPS-1 promotes the survival of circulating erythrocytes through inhibition of phagocytosis by splenic macrophages.	SIRPB1 SIRPA	2.26e-05	3	96	2	16141346
Pubmed	Deletion of SIRPα (signal regulatory protein-α) promotes phagocytic clearance of myelin debris in Wallerian degeneration, axon regeneration, and recovery from nerve injury.	SIRPB1 SIRPA	2.26e-05	3	96	2	31883525
Pubmed	Signal regulatory protein α is associated with tumor-polarized macrophages phenotype switch and plays a pivotal role in tumor progression.	SIRPB1 SIRPA	2.26e-05	3	96	2	23504854
Pubmed	SIRPα signaling regulates podocyte structure and function.	SIRPB1 SIRPA	2.26e-05	3	96	2	23842779
Pubmed	Essential roles of SIRPα in homeostatic regulation of skin dendritic cells.	SIRPB1 SIRPA	2.26e-05	3	96	2	20955735
Pubmed	A role for SHPS-1/SIRPalpha in Concanavalin A-dependent production of MMP-9.	SIRPB1 SIRPA	2.26e-05	3	96	2	17825046
Pubmed	SIRPα deficiency accelerates the pathologic process in models of Parkinson disease.	SIRPB1 SIRPA	2.26e-05	3	96	2	31322787
Pubmed	Soluble SIRP-Alpha Promotes Murine Acute Lung Injury Through Suppressing Macrophage Phagocytosis.	SIRPB1 SIRPA	2.26e-05	3	96	2	35634325
Pubmed	Novel insights into the expression of CGB1 & 2 genes by epithelial cancer cell lines secreting ectopic free hCGβ.	CGB3 CGB1	2.26e-05	3	96	2	24778026
Pubmed	The Rho kinase pathway regulates the migration of dendritic cells through SIRP-α.	SIRPB1 SIRPA	2.26e-05	3	96	2	22391241
Pubmed	The murine P84 neural adhesion molecule is SHPS-1, a member of the phosphatase-binding protein family.	SIRPB1 SIRPA	2.26e-05	3	96	2	9348339
Pubmed	Targeting SIRP-α protects from type 2-driven allergic airway inflammation.	SIRPB1 SIRPA	2.26e-05	3	96	2	21108471
Pubmed	Mutational analysis of the mechanism of negative regulation by SRC homology 2 domain-containing protein tyrosine phosphatase substrate-1 of phagocytosis in macrophages.	SIRPB1 SIRPA	2.26e-05	3	96	2	16920950
Pubmed	Src homology 2 domain-containing protein tyrosine phosphatase substrate 1 regulates the induction of Langerhans cell maturation.	SIRPB1 SIRPA	2.26e-05	3	96	2	17109464
Pubmed	Signal regulatory protein α negatively regulates mast-cell activation following FcεRI aggregation.	SIRPB1 SIRPA	2.26e-05	3	96	2	23504624
Pubmed	Expression of recipient CD47 on rat insulinoma cell xenografts prevents macrophage-mediated rejection through SIRPα inhibitory signaling in mice.	SIRPB1 SIRPA	2.26e-05	3	96	2	23472187
Pubmed	SIRP/CD47 signaling in neurological disorders.	SIRPB1 SIRPA	2.26e-05	3	96	2	25795378
Pubmed	Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103(+) CD11b(+) DCs in the intestinal lamina propria.	SIRPB1 SIRPA	2.26e-05	3	96	2	25236797
Pubmed	Deficiency in SIRP-α cytoplasmic recruitment confers protection from acute kidney injury.	SIRPB1 SIRPA	2.26e-05	3	96	2	31370677
Pubmed	A functional subset of CD8+ T cells during chronic exhaustion is defined by SIRPα expression.	SIRPB1 SIRPA	2.26e-05	3	96	2	30770827
Pubmed	Signal regulatory protein α protects podocytes through promoting autophagic activity.	SIRPB1 SIRPA	2.26e-05	3	96	2	30888336
Pubmed	Podocyte SIRPα reduction aggravates lupus nephritis via promoting T cell inflammatory responses.	SIRPB1 SIRPA	2.26e-05	3	96	2	38758648
Pubmed	Loss of microglial SIRPα promotes synaptic pruning in preclinical models of neurodegeneration.	SIRPB1 SIRPA	2.26e-05	3	96	2	33795678
Pubmed	Requirement of SIRPα for protective immunity against Leishmania major.	SIRPB1 SIRPA	2.26e-05	3	96	2	20854790
Pubmed	Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 mutant mice.	SIRPB1 SIRPA	2.26e-05	3	96	2	17617577
Pubmed	BIT, an immune antigen receptor-like molecule in the brain.	SIRPB1 SIRPA	2.26e-05	3	96	2	9271230
Pubmed	Gene structure of mouse BIT/SHPS-1.	SIRPB1 SIRPA	2.26e-05	3	96	2	10585853
Pubmed	Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP(2).	CGB3 CGB7	2.26e-05	3	96	2	10468638
Pubmed	Expression of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 in pancreatic beta-Cells and its role in promotion of insulin secretion and protection against diabetes.	SIRPB1 SIRPA	2.26e-05	3	96	2	18635660
Pubmed	Tyrosine phosphorylation of the transmembrane protein SIRPα: Sensing synaptic activity and regulating ectodomain cleavage for synapse maturation.	SIRPB1 SIRPA	2.26e-05	3	96	2	29914984
Pubmed	SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility.	SIRPB1 SIRPA	2.26e-05	3	96	2	11118207
Pubmed	Intratumoral SIRPα-deficient macrophages activate tumor antigen-specific cytotoxic T cells under radiotherapy.	SIRPB1 SIRPA	2.26e-05	3	96	2	34050181
Pubmed	Ectodomain shedding of SHPS-1 and its role in regulation of cell migration.	SIRPB1 SIRPA	2.26e-05	3	96	2	15123722
Pubmed	SIRPα+ dendritic cells promote the development of fibroblastic reticular cells in murine peripheral lymph nodes.	SIRPB1 SIRPA	2.26e-05	3	96	2	31099900
Pubmed	Chorionic gonadotropin has a recent origin within primates and an evolutionary history of selection.	CGB3 CGB7	2.26e-05	3	96	2	11861891
Pubmed	Selective SIRPα blockade reverses tumor T cell exclusion and overcomes cancer immunotherapy resistance.	SIRPB1 SIRPA	2.26e-05	3	96	2	33074246
Pubmed	Identification of MAGI-3 as a transforming growth factor-alpha tail binding protein.	MAGI3 MAGI2	2.26e-05	3	96	2	15652357
Pubmed	Resistance to collagen-induced arthritis in SHPS-1 mutant mice.	SIRPB1 SIRPA	2.26e-05	3	96	2	18455510
Pubmed	Regulation of Phagocyte Migration by Signal Regulatory Protein-Alpha Signaling.	SIRPB1 SIRPA	2.26e-05	3	96	2	26057870
Pubmed	Essential roles of SHPS-1 in induction of contact hypersensitivity of skin.	SIRPB1 SIRPA	2.26e-05	3	96	2	18809435
Pubmed	Signal regulatory protein alpha (SIRPalpha)/CD47 interaction and function.	SIRPB1 SIRPA	2.26e-05	3	96	2	19223164
Pubmed	Negative regulation by SHPS-1 of Toll-like receptor-dependent proinflammatory cytokine production in macrophages.	SIRPB1 SIRPA	2.26e-05	3	96	2	18233962
Pubmed	Suppression of SHP-1 promotes corticospinal tract sprouting and functional recovery after brain injury.	SIRPB1 SIRPA	2.26e-05	3	96	2	23559001
Pubmed	SHPS-1 deficiency induces robust neuroprotection against experimental stroke by attenuating oxidative stress.	SIRPB1 SIRPA	2.26e-05	3	96	2	22671569
Pubmed	Endothelial SIRPα signaling controls VE-cadherin endocytosis for thymic homing of progenitor cells.	SIRPB1 SIRPA	2.26e-05	3	96	2	35511221
Pubmed	Role of disulfide bond formation in the folding of human chorionic gonadotropin beta subunit into an alpha beta dimer assembly-competent form.	CGB3 CGB7	2.26e-05	3	96	2	1688430
Pubmed	Regulation by Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 of alpha-galactosylceramide-induced antimetastatic activity and Th1 and Th2 responses of NKT cells.	SIRPB1 SIRPA	2.26e-05	3	96	2	17475843
Pubmed	Schlafen 11 triggers innate immune responses through its ribonuclease activity upon detection of single-stranded DNA.	SLFN13 SLFN11	2.26e-05	3	96	2	38875319
Pubmed	Focal cerebral ischemia upregulates SHP-1 in reactive astrocytes in juvenile mice.	SIRPB1 SIRPA	2.26e-05	3	96	2	12742627
Pubmed	Dendritic cell SIRPα regulates homeostasis of dendritic cells in lymphoid organs.	SIRPB1 SIRPA	2.26e-05	3	96	2	25818708
Pubmed	SIRPα Mediates IGF1 Receptor in Cardiomyopathy Induced by Chronic Kidney Disease.	SIRPB1 SIRPA	4.51e-05	4	96	2	35722884
Pubmed	Macrophages require Skap2 and Sirpα for integrin-stimulated cytoskeletal rearrangement.	SIRPB1 SIRPA	4.51e-05	4	96	2	22976304
Pubmed	Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways.	SIRPB1 SIRPA	4.51e-05	4	96	2	34097709
Pubmed	Down-regulation of platelet surface CD47 expression in Escherichia coli O157:H7 infection-induced thrombocytopenia.	SIRPB1 SIRPA	4.51e-05	4	96	2	19771158
Pubmed	Inflammation Unrestrained by SIRPα Induces Secondary Hemophagocytic Lymphohistiocytosis Independent of IFN-γ.	SIRPB1 SIRPA	4.51e-05	4	96	2	33028619
Pubmed	Loss of Cell Surface CD47 Clustering Formation and Binding Avidity to SIRPα Facilitate Apoptotic Cell Clearance by Macrophages.	SIRPB1 SIRPA	4.51e-05	4	96	2	26085683
Pubmed	Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability.	CCNA1 PLK1	4.51e-05	4	96	2	29154753
Pubmed	Abnormal chemokine-induced responses of immature and mature hematopoietic cells from motheaten mice implicate the protein tyrosine phosphatase SHP-1 in chemokine responses.	SIRPB1 SIRPA	4.51e-05	4	96	2	10477552
Pubmed	'Clustering' SIRPα into the plasma membrane lipid microdomains is required for activated monocytes and macrophages to mediate effective cell surface interactions with CD47.	SIRPB1 SIRPA	4.51e-05	4	96	2	24143245
Pubmed	Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection.	SIRPB1 SIRPA	4.51e-05	4	96	2	32294445
Pubmed	Polymorphism in the innate immune receptor SIRPα controls CD47 binding and autoimmunity in the nonobese diabetic mouse.	SIRPB1 SIRPA	4.51e-05	4	96	2	25305319
Pubmed	Myelin down-regulates myelin phagocytosis by microglia and macrophages through interactions between CD47 on myelin and SIRPα (signal regulatory protein-α) on phagocytes.	SIRPB1 SIRPA	4.51e-05	4	96	2	21401967
Pubmed	Tethering of apoptotic cells to phagocytes through binding of CD47 to Src homology 2 domain-bearing protein tyrosine phosphatase substrate-1.	SIRPB1 SIRPA	4.51e-05	4	96	2	14634079
Pubmed	CD47-signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction.	SIRPB1 SIRPA	4.51e-05	4	96	2	22042861
Pubmed	Membrane mobility and clustering of Integrin Associated Protein (IAP, CD47)--major differences between mouse and man and implications for signaling.	SIRPB1 SIRPA	4.51e-05	4	96	2	16697668
GeneFamily	Olfactory receptors, family 9	OR9A4 OR9A1P OR9A2	6.79e-05	23	63	3	156
GeneFamily	CD molecules\|V-set domain containing\|C1-set domain containing\|Signal regulatory proteins	SIRPB1 SIRPA	1.19e-04	5	63	2	747
GeneFamily	Schlafen family	SLFN13 SLFN11	2.48e-04	7	63	2	1110
GeneFamily	Myosin heavy chains	MYH7B MYH14	1.22e-03	15	63	2	1098
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	MAGI3 MAGI2	3.68e-03	26	63	2	904
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POLE TRIP13 KIF20B RECQL4 NCAPD2 JAKMIP1 PLK1	9.08e-08	171	96	7	1eebd7138c3b20ddc1104f21615f9df0e776bbe6
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4\|Striatum / BrainAtlas - Mouse McCarroll V32	ILF2 POLE TRIP13 KIF20B RECQL4 NCAPD2 PLK1	1.11e-07	176	96	7	d70fdc7bc48719776ed1e7c01118385e3a21623f
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_1\|Striatum / BrainAtlas - Mouse McCarroll V32	ILF2 POLE TRIP13 KIF20B RECQL4 NCAPD2 PLK1	1.11e-07	176	96	7	a84361308e5e96f3a30246cd29e109c321ee65bf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SH3TC2 POLE KIF20B SLFN13 NCAPD2 PLK1	1.80e-06	169	96	6	b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUC5B SSPOP RYR3 PKHD1 ONECUT3 UNC79	2.95e-06	184	96	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUC5B SSPOP RYR3 PKHD1 ONECUT3 UNC79	2.95e-06	184	96	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUC5B SSPOP RYR3 PKHD1 ONECUT3 UNC79	2.95e-06	184	96	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	POLE MUC5B KIF20B RECQL4 NCAPD2 PLK1	3.04e-06	185	96	6	47c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCell	343B-Lymphocytic-ILC-ILC-1\|343B / Donor, Lineage, Cell class and subclass (all cells)	SOCS6 NUP205 SP140L CSKMT SLFN11 METTL16	3.33e-06	188	96	6	8f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRIP13 KIF20B SLFN13 RECQL4 NCAPD2 PLK1	3.99e-06	194	96	6	1a2090e997c70433d07f56bf7cb0a50c4151118c
ToppCell	Healthy_Control-Lymphoid-T-Proliferating_T\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	TRIP13 KIF20B SLFN13 RECQL4 NCAPD2 PLK1	4.36e-06	197	96	6	3ce3dcbbe0edeb5a6fb5596dd6c2b4d6c1d5159d
ToppCell	MNPs-Dividing_Macrophages\|MNPs / lung cells shred on cell class, cell subclass, sample id	TRIP13 KIF20B SLFN13 RECQL4 NCAPD2 PLK1	4.62e-06	199	96	6	5952980d0ece5d73f3e9f340c56a38b34d2f2309
ToppCell	10x5'-Lung-Myeloid_Mac-Cycling_Myeloid-Mac\|Lung / Manually curated celltypes from each tissue	TRIP13 KIF20B SLFN13 RECQL4 NCAPD2 PLK1	4.62e-06	199	96	6	dee1cf8ee850a2bd57349418a9bcc0948fe9ac9e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal-BMP_responsible_cell\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	SP100 SIRPA MGST2 TLR5 SLFN11 DOCK6	4.76e-06	200	96	6	01d707c4f8ee0daac635b7260937b1baebc6fc23
ToppCell	LAM-Myeloid-pMacrophage\|Myeloid / Condition, Lineage and Cell class	TRIP13 KIF20B SLFN13 RECQL4 NCAPD2 PLK1	4.76e-06	200	96	6	0078d56337d44074326e8ccd1d412d098d86eeab
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRIP13 KIF20B SLFN13 RECQL4 NCAPD2 PLK1	4.76e-06	200	96	6	28c702449040ac15fe4e0c6340bb6f137e88539d
ToppCell	(3)_MNP-(3)_DC_Monocyte_Dividing\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	TRIP13 KIF20B SLFN13 RECQL4 NCAPD2 PLK1	4.76e-06	200	96	6	d94fe9bd6ee7c1fed14666f24de41bda014e299b
ToppCell	BAL-Control-cDC_12\|Control / Compartment, Disease Groups and Clusters	SPOUT1 TRIP13 SLFN13 RECQL4 PLK1	2.09e-05	154	96	5	0121d08cc527aed9b3e11ff62bb9012916f5c56b
ToppCell	10x5'-Lung-Myeloid_Monocytic-Cycling_mono\|Lung / Manually curated celltypes from each tissue	VIRMA RECQL4 NCAPD2 SPACA6 PLK1	2.23e-05	156	96	5	63b8cf14361b282872bc1c5b65d9fbc83e81a089
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPOUT1 TRIP13 KIF20B SPACA6 ADAMTS14	2.37e-05	158	96	5	ee8ce3cd202807df692b28bb1a81827d49d73862
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SIRPA TRIP13 KIF20B NCAPD2 PLK1	2.91e-05	165	96	5	1dcd6b8aa192baeaa1f7bb334843edab6049b96f
ToppCell	10x5'-Lung-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|Lung / Manually curated celltypes from each tissue	TRIP13 KIF20B SLC26A8 NCAPD2 PLK1	3.09e-05	167	96	5	82739226347d74897be000f429b73543a031af96
ToppCell	10x5'-Lung-Hematopoietic_progenitors\|Lung / Manually curated celltypes from each tissue	TRIP13 KIF20B SLC26A8 NCAPD2 PLK1	3.09e-05	167	96	5	dec18caf0475002d4ad3c7bc7fc3050cbc8e6bae
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PIWIL1 TRIP13 KIF20B NCAPD2 PLK1	3.27e-05	169	96	5	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NMUR2 KIF20B DZANK1 NCAPD2 PLK1	3.46e-05	171	96	5	05014cf6746e6663e376fdd681f1b43a7081c603
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NMUR2 KIF20B DZANK1 NCAPD2 PLK1	3.46e-05	171	96	5	d6114db2292fbb27b39d090d51fd305a135b1ccf
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ILF2 TRIP13 KIF20B NCAPD2 PLK1	3.55e-05	172	96	5	7f3d0ef18f5df1ed80498d435b0378ca398c0b88
ToppCell	droplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRIP13 KIF20B NCAPD2 ADAMTS14 PLK1	3.65e-05	173	96	5	c399786aa25bdbe3394988db6955842b5b7e6b41
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIP13 KIF20B NCAPD2 ADAMTS14 PLK1	3.65e-05	173	96	5	31784679190fbd95fc23d7c66008eb21b8c7cc5d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AADACL4 KIF20B SLFN13 RECQL4 NCAPD2	3.65e-05	173	96	5	a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SH3TC2 POLE KIF20B SLFN13 RECQL4	3.76e-05	174	96	5	84da9faff088d05233183b425385beb054c92d1b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SH3TC2 KIF20B SLFN13 NCAPD2 PLK1	3.76e-05	174	96	5	dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KHNYN KIF20B NCAPD2 JAKMIP1 PLK1	3.86e-05	175	96	5	9de288c338cee67be0e9b836c87799bbc1db1c38
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Stmn2))\|Striatum / BrainAtlas - Mouse McCarroll V32	POLE TRIP13 SLC26A8 RECQL4	4.32e-05	90	96	4	7efc3437489c8587b9805547da1095f50d20cf6d
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ILF2 TRIP13 KIF20B NCAPD2 PLK1	4.41e-05	180	96	5	ed4966765a6b25456f68185cf0648c4a3a21d7fe
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAGI3 MYH14 ST6GALNAC3 PKHD1 TMPRSS2	4.53e-05	181	96	5	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	POLE MUC5B RECQL4 NCAPD2 PLK1	4.77e-05	183	96	5	6c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ILF2 TRIP13 KIF20B NCAPD2 PLK1	5.03e-05	185	96	5	6aeae77a087d695b1e58c5f63265e7113aa2e343
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi\|lung / Disease (COVID-19 only), tissue and cell type	FCRL2 SLAMF1 KIF20B RECQL4 TRAM2	5.16e-05	186	96	5	66676d9395172de5707e204826a1c9f73b448cca
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SIRPA RYR3 MAGI2 ST6GALNAC3 ADAMTS14	5.29e-05	187	96	5	24c2a3962da364e46e98abeab5f8234376fa26bb
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_int\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FCRL2 SLAMF1 KIF20B RECQL4 TRAM2	5.43e-05	188	96	5	599195338070ac6b79bd114609d9e10cac4f1df4
ToppCell	3'_v3-bone_marrow-Lymphocytic_B_plasma-Plasmablasts\|bone_marrow / Manually curated celltypes from each tissue	FCRL2 TRIP13 NLRP14 TRAM2 PLK1	5.43e-05	188	96	5	4caae2acd9ec0eb79b7476a1e59f30f39afddcda
ToppCell	droplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	POLE TRIP13 KIF20B NCAPD2 PLK1	5.43e-05	188	96	5	0ec2a1b0505501ba18f10a5fce68c306a6292419
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FCRL2 SLAMF1 KIF20B RECQL4 TRAM2	5.43e-05	188	96	5	567b08514d9d84cbb40f9b7a679eec304f023428
ToppCell	Dividing_Macrophages-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	KIF20B SLFN13 RECQL4 NCAPD2 PLK1	5.56e-05	189	96	5	d4e88a3e50499d683e3db38aee04490146fe30bb
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	POLE KIF20B RECQL4 NCAPD2 PLK1	5.56e-05	189	96	5	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI3 SLC1A2 MYH14 PKHD1 TMPRSS2	5.70e-05	190	96	5	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	(02)_Cycling_Basal_(regeneration)\|World / shred by cell type and Timepoint	POLE TRIP13 KIF20B NCAPD2 PLK1	5.70e-05	190	96	5	53f017a11ca5ebe9025558e12cedc409cab2e5aa
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-naive_B_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FCRL2 SP100 SLAMF1 SP140L CSKMT	5.85e-05	191	96	5	a073d58154c801ec499fd969f42b7f1ee7f15d79
ToppCell	Dividing_Macrophages-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	TRIP13 KIF20B RECQL4 NCAPD2 PLK1	5.85e-05	191	96	5	3e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POLE TRIP13 KIF20B NCAPD2 UNC79	5.85e-05	191	96	5	c8b99bd3a30c81ee4deba9cbf0196920ab3ab550
ToppCell	343B-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SOCS6 NUP205 CSKMT SLFN11 METTL16	5.99e-05	192	96	5	445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRIP13 KIF20B RECQL4 NCAPD2 PLK1	6.30e-05	194	96	5	cb39850e9577015b6b9834e98c36b412bae7d462
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRIP13 KIF20B RECQL4 NCAPD2 PLK1	6.30e-05	194	96	5	408597c9aa302a44b112c1d612c21fbb0227a82a
ToppCell	BAL-Severe-Myeloid-Myeloid\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRIP13 KIF20B RECQL4 NCAPD2 PLK1	6.30e-05	194	96	5	2360b5f995b360419de41612368cab9fb61781a1
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLE TRIP13 KIF20B NCAPD2 PLK1	6.30e-05	194	96	5	3a49c7c86036e09a8cd0114988380d04ad1a26fb
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLE TRIP13 KIF20B NCAPD2 PLK1	6.45e-05	195	96	5	5790b47b0e028e49b99bda8d6d9e80ac79208cdf
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TRIP13 KIF20B SLFN13 NCAPD2 PLK1	6.61e-05	196	96	5	9591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCell	(3)_MNP-(3)_Macrophage_Dividing\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	TRIP13 KIF20B SLFN13 NCAPD2 PLK1	6.77e-05	197	96	5	048bc4f8fd5d4f394e2384700640f72042336597
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILF2 TRIP13 KIF20B NCAPD2 PLK1	6.77e-05	197	96	5	f84f0ddf51208764ab56408d97035bbff562e59d
ToppCell	distal-3-Hematologic-Proliferating_NK/T\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TRIP13 KIF20B RECQL4 NCAPD2 PLK1	6.93e-05	198	96	5	aa23119d73554733981df474648e59918d04edfc
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_dorsal_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	TRIP13 KIF20B NCAPD2 CCNA1 PLK1	6.93e-05	198	96	5	5f0964c3aa7e1dc52cbb46e754078920b65bcb88
ToppCell	(3)_DC_Monocyte_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	TRIP13 KIF20B RECQL4 NCAPD2 PLK1	6.93e-05	198	96	5	e2b89f6d7c0007ccab62495cd543fe0e5513a9a4
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	TRIP13 KIF20B NCAPD2 CCNA1 PLK1	6.93e-05	198	96	5	629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	TRIP13 KIF20B SLFN13 RECQL4 PLK1	6.93e-05	198	96	5	6a10bb81817ab606f1f5a2bd8cfe77ef2fb3f2fb
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ILF2 KIF20B NCAPD2 CCNA1 PLK1	6.93e-05	198	96	5	c3dd887c95587f930b7afd32385627a9fa029ca4
ToppCell	medial-2-Hematologic-Proliferating_Macrophage\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	POLE TRIP13 KIF20B RECQL4 PLK1	6.93e-05	198	96	5	64a2bcf5a9ba66a4fe08fbde33f1886c136cde8f
ToppCell	medial-Hematologic-Proliferating_Macrophage-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	POLE TRIP13 KIF20B RECQL4 PLK1	6.93e-05	198	96	5	fcc14ac3eb5088b9d6cd6af5a34dee5b81c0ece8
ToppCell	distal-Hematologic-Proliferating_Macrophage-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TRIP13 KIF20B RECQL4 NCAPD2 PLK1	6.93e-05	198	96	5	8afeb1f9bc9d8551482c8fefe4c5f88d9cd13ee2
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_dorsal_progenitors\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	TRIP13 KIF20B NCAPD2 CCNA1 PLK1	6.93e-05	198	96	5	dada1c19a261c8e1090957cd7e37f2a43a9fe14f
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KIF20B SLFN13 RECQL4 NCAPD2 PLK1	6.93e-05	198	96	5	281fc2536cdc4c717b30de156e563c0e4baba99d
ToppCell	medial-Hematologic-Proliferating_Macrophage\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	POLE TRIP13 KIF20B RECQL4 PLK1	6.93e-05	198	96	5	da6963184c32761c896a9b91a5321ad84b583736
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRIP13 KIF20B SLFN13 NCAPD2 PLK1	7.10e-05	199	96	5	4af38f5e9d2229d64f7ecdf9c00b4d67e5f86a51
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_dorsal_progenitors\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	TRIP13 KIF20B NCAPD2 CCNA1 PLK1	7.10e-05	199	96	5	ca17e8c0f5bc2c41ce28351a7418d934404e563b
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	TRIP13 KIF20B SLFN13 NCAPD2 PLK1	7.10e-05	199	96	5	88d130e2451e61afb710edf552e6b346b9fcfb2b
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	TRIP13 KIF20B NCAPD2 CCNA1 PLK1	7.10e-05	199	96	5	d8f904f531bfe091b7d8caaa147ea4a03d627995
ToppCell	Dividing_Macrophages\|World / lung cells shred on cell class, cell subclass, sample id	TRIP13 KIF20B RECQL4 NCAPD2 PLK1	7.10e-05	199	96	5	5c755b6876e164dc847ef7c723f850f227cf3a87
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	SP100 SIRPA MGST2 TLR5 SLFN11	7.27e-05	200	96	5	0eccf41edefc3b8b5d0316f57d5ba572949aec2b
ToppCell	distal-Hematologic-Proliferating_Macrophage\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TRIP13 KIF20B RECQL4 NCAPD2 PLK1	7.27e-05	200	96	5	3835a8a9739b8cd5bf19c40765ef76907ac1ad38
ToppCell	distal-2-Hematologic-Proliferating_Macrophage\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TRIP13 KIF20B RECQL4 NCAPD2 PLK1	7.27e-05	200	96	5	0cd3b01fb7f579e5abf000adb8ec8adc7cd779c4
ToppCell	Severe-T/NK_proliferative\|Severe / Disease group and Cell class	TRIP13 KIF20B NCAPD2 PLK1 SNRPF	7.27e-05	200	96	5	4723613a9f56bff422fc98722128d57b6adf3c5d
ToppCell	LAM-Myeloid-pMacrophage\|LAM / Condition, Lineage and Cell class	TRIP13 KIF20B RECQL4 NCAPD2 PLK1	7.27e-05	200	96	5	7e233d037165c9d3607604aaaf0f368e266567d3
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Stem_cells\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	TRIP13 KIF20B NCAPD2 CCNA1 PLK1	7.27e-05	200	96	5	008f137920cc3b599376706803c111d1d0ec17ef
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Mesenchymal\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	SH3TC2 SP100 XKR8 MGST2 SP140L	7.27e-05	200	96	5	5c638c80661017c85f9390f1b398ac7728c8f001
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Mesenchymal-BMP_responsible_cell\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	SH3TC2 SP100 XKR8 MGST2 SP140L	7.27e-05	200	96	5	604a88633d4162337e394155c7346dbdef8b9f5a
ToppCell	Biopsy_Other_PF-Immune-Proliferating_Macrophages\|Biopsy_Other_PF / Sample group, Lineage and Cell type	TRIP13 KIF20B RECQL4 NCAPD2 PLK1	7.27e-05	200	96	5	61473e8613f39a92002d5b631e6bd563735566e4
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SH3TC2 POLE KIF20B SLFN13 RECQL4	7.27e-05	200	96	5	af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Stem_cells-Neuroepithelial_cell\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	TRIP13 KIF20B NCAPD2 CCNA1 PLK1	7.27e-05	200	96	5	0e119c2742f2be19fde8890d1227bf277ead976f
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TRIP13 KIF20B RECQL4 NCAPD2 PLK1	7.27e-05	200	96	5	5b014c658eecc5e73679e5feb7a2aaa3d297001d
ToppCell	mild-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	POLE TRIP13 SLFN13 NCAPD2 PLK1	7.27e-05	200	96	5	63cc57b9331459efbb73051d174d198a3568b938
ToppCell	Endothelial-H_(cycle)\|World / shred on cell class and cell subclass (v4)	ILF2 KIF20B NCAPD2 PLK1	1.96e-04	133	96	4	8e3005114761feee028c496cc739e607b35d7831
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	POLE TRIP13 KIF20B PLK1	2.95e-04	148	96	4	b9d3421c2eb8e748e9508c1cbd1cb4f96e23db5a
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4\|Hippocampus / BrainAtlas - Mouse McCarroll V32	POLE TRIP13 KIF20B PLK1	2.95e-04	148	96	4	2a7671dc27afbdf6a92d976c5f2b728bd18dd609
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RNF144B MYH7B MAGI3 RYR3	3.03e-04	149	96	4	10ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NMUR2 TRIP13 SMIM23 SLFN13	3.35e-04	153	96	4	499670e716fc85ce76630fc813cec86f8419f2a1
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-midbrain/hindbrain_cells\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	RYR3 MGST2 TLR5 ONECUT3	3.43e-04	154	96	4	df1b58a20af73fa79c6c069c0117a9ffd85b476f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SIRPA RYR3 MAGI2 ST6GALNAC3	3.52e-04	155	96	4	90e629681a72baacc7981b82883866a487638dbc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SIRPA RYR3 MAGI2 ST6GALNAC3	3.52e-04	155	96	4	e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SIRPA RYR3 MAGI2 ST6GALNAC3	3.52e-04	155	96	4	5a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCell	severe_COVID-19-cDC\|World / disease group, cell group and cell class (v2)	RIMKLA PIWIL1 MGST2 KIF17	3.61e-04	156	96	4	0a7e18ed8e13261c405eb6b9a183e99d8e1aac37
Computational	Genes in the cancer module 198.	ILF2 POLE RFC1 TRIP13 RECQL4 NCAPD2 CCNA1 PLK1	2.66e-05	303	44	8	MODULE_198
Computational	Response to DNA damage.	ILF2 POLE RFC1 TRIP13 RECQL4 PLK1	1.04e-04	187	44	6	MODULE_244
Computational	Genes in the cancer module 98.	ILF2 POLE RFC1 TRIP13 RECQL4 NCAPD2 CCNA1 PLK1	1.66e-04	393	44	8	MODULE_98
Computational	Neighborhood of AIP	ILF2 TRIP13 PLK1	5.69e-04	40	44	3	GCM_AIP
Disease	level of tyrosine-protein phosphatase non-receptor type substrate 1 in blood serum	SIRPB1 SIRPA	9.00e-06	2	89	2	OBA_2040362
Disease	Epileptic encephalopathy	SLC1A2 RYR3 MAGI2	1.02e-04	30	89	3	C0543888
Disease	signal-regulatory protein beta-1 measurement	SIRPB1 SIRPA	3.19e-04	9	89	2	EFO_0802069
Disease	Dental enamel hypoplasia	MYH7B MYH14	5.82e-04	12	89	2	EFO_1001304
Disease	Charcot-Marie-Tooth disease type 4	SH3TC2 SBF1	6.87e-04	13	89	2	cv:C4082197
Disease	glucose homeostasis measurement, glucose effectiveness measurement	MYH7B MYH14	9.21e-04	15	89	2	EFO_0006833, EFO_0006896

Protein segments in the cluster

Peptide	Gene	Start	Entry
YCQRQGVPVNSLRFL	SUMO1P1	51	G2XKQ0
PCIFRLVSQFIQNRI	nan	541	Q9N2K0
LRPRVNCLQDFSYQR	ERVK-18	91	O42043
ALPQVVCNYRDVRFE	CGB1	101	A6NKQ9
RAQVLIYPVVQAFCL	AADACL4	216	Q5VUY2
RELFRQPLRQECVYT	ADAMTS14	141	Q8WXS8
RCQINIYDRLNRTPL	ANKRD19P	91	Q9H560
FENLRQRGYQVCPVL	MUC5B	1361	Q9HC84
LYFTIQEANQRPRCQ	MSANTD5	96	A0A3B3IT52
LCYLIRFLQVFVQPA	ARHGAP39	1011	Q9C0H5
DYPQVQILRALRQRC	RIMKLA	16	Q8IXN7
YRQILLPALQLCQVI	NUP205	1616	Q92621
IACLVPVDQFQLYQR	RNF144B	91	Q7Z419
CRLLGNVPFRLQEYE	PCDH19	386	Q8TAB3
LYVFQLPFCRSRLIN	OR2AK2	176	Q8NG84
NLYQNCIRYIPEAIL	LRCH3	111	Q96II8
QQIIRDNLYLRTVPC	MAGI2	126	Q86UL8
QQVIRDNLYLRTIPC	MAGI3	131	Q5TCQ9
AVNPIIYNLLSRRFQ	NMUR2	321	Q9GZQ4
NAIQFVPVRIFQDCR	LRRTM1	171	Q86UE6
CPLCRQDIAQRLRIY	LRSAM1	706	Q6UWE0
LPLYLICYRRQLERQ	SLC43A2	531	Q8N370
ALPQVVCNYRDVRFE	CGB7	71	P0DN87
RICRQGFPNRILFQE	MYH14	726	Q7Z406
IRICRQGFPNRLLYT	MYH7B	751	A7E2Y1
RCTLQPVLENRAYRE	PNMA6E	306	A0A0J9YXQ4
GRNRIRQFFCNIPQL	OR14L1P	171	Q8NHC6
ANVIRYIVCRALQFP	PGAM5	231	Q96HS1
RAYQLLSECLRVLNP	CSKMT	176	A8MUP2
KDYLQVCLRIRPFTQ	KIF20B	56	Q96Q89
QLCTYIRNQIFRLVA	METTL16	546	Q86W50
LRFCQLTREYQALQR	JAKMIP1	486	Q96N16
HCIRLSIPRVFYVNQ	POLE	1356	Q07864
LQRVSRCYRQNRFPV	SBF1	1181	O95248
CQIIYPRQQLLTLRE	TRIP13	341	Q15645
DRYVAVCNPLRYNII	OR9A1P	121	Q8NGU1
NTIGLQFQRYRLIPC	BECN2	301	A8MW95
IRQIRQACAQPFEAF	CHCHD5	51	Q9BSY4
GIYRVCQVLFRLNFL	CASD1	486	Q96PB1
NYCRLREALQPLLTQ	DOCK6	2006	Q96HP0
ALPQVVCNYRDVRFE	CGB3	71	P0DN86
QLLRAIYVPQNVYCI	GCNT7	126	Q6ZNI0
LIRNLFPENLVQACF	SLC1A2	171	P43004
QFLLQYLRRQGVCVR	CCNA1	346	P78396
VRYRYQPLLERCNNV	FASTKD1	241	Q53R41
PLALNVAYRRCLQIL	ILF2	261	Q12905
ILQREPYCRDINQLS	KHNYN	656	O15037
RLSPQRLDVQLQFCF	FCRL2	131	Q96LA5
LRCYAQNNPEFRALI	DZANK1	491	Q9NVP4
CVIKQDQRPLARLYF	SPACA6	226	W5XKT8
RILYVCENQPLRNFI	SLFN13	626	Q68D06
IIQRIFVHYPRQQEC	ECSIT	146	Q9BQ95
QLARILQYLECPQYL	SPOUT1	141	Q5T280
IQRLCELLTDPRRNY	PPP4R2	101	Q9NY27
VDRYVAVCNPLRYNI	OR9A2	116	Q8NGT5
RYSIPQAIFAQRILC	ONECUT3	336	O60422
LEQVQPLIRRDCNYS	KIF17	861	Q9P2E2
RAQQNCVEFYPIFII	MGST2	51	Q99735
PTCLQFYNIIFRRLL	PIWIL1	206	Q96J94
VRFFQRCLQVLPERY	PGGT1B	26	P53609
ARIQLCDNDIYFIPR	RSBN1	666	Q5VWQ0
RQPFVLRCAVLYCFQ	USO1	376	O60763
LRANCYQRFVVPLLS	TRMT1	301	Q9NXH9
CRVRDVLDFYNVPIQ	MRPL50	121	Q8N5N7
PNILTAYQERRFCNL	SSPOP	3986	A2VEC9
RNALCVIPQDFFQLL	LRRC27	76	Q9C0I9
YCFDLRFQRPRVEQI	RFC1	766	P35251
RFQNLDSIIIYCNRR	RECQL4	696	O94761
LRINKCIRISFNQYP	SLC26A8	291	Q96RN1
CLALRIPFYRSNVIN	OR5L1	161	Q8NGL2
LQYKRQNPAQFCVRV	RETREG2	176	Q8NC44
VSVQRFCLQLRLYEQ	SLAMF1	126	Q13291
RIRECNYYQNLAVPQ	SMIM23	61	A6NLE4
RLVNEVNFPLLLNCF	ST6GALNAC3	26	Q8NDV1
VTCQVRKFYPQRLQL	SIRPA	271	P78324
RILYVCENQPLRNFI	SLFN11	626	Q7Z7L1
RRFVDYCLQKIPQER	TAOK3	251	Q9H2K8
RNYLLQAVRLYCELQ	SH3TC2	896	Q8TF17
PQQIQAFDQLCRLYR	VPS8	1361	Q8N3P4
QLLLLCPDFRQERQQ	PKHD1	4016	P08F94
CRNLVPVQRVVYNVL	SP140L	96	Q9H930
DRYVAVCNPLRYNII	OR9A4	121	Q8NGU2
TCQVRKFYPQRLQLT	SIRPB1	271	Q5TFQ8
RQQRDLAYCVSQLPL	NCAPD2	1221	Q15021
LQVPERQVDCRVQLY	nan	216	Q6ZTK2
NRCVRLYGPNFILQV	TMPRSS2	146	O15393
LRRLVFDVPQLNEYC	RYR3	2486	Q15413
EEIPRQLQYICLYLV	TRAM2	186	Q15035
CRNLVPVQRVVYNVL	SP100	96	P23497
LVPKQLRFCRNYIEI	WNT3	51	P56703
EVLIRCNNVLYIRGV	SNRPF	61	P62306
AFYRFCNLTQVPQVL	TLR5	31	O60602
LRFEINCIPNLIEYV	VIRMA	901	Q69YN4
QVRSLQYLCRFVIRQ	SOCS6	496	O14544
NPYCRTLFNELRIVV	TMEM33	201	P57088
QRNDVFYLQPERSCV	ZMYM4	1486	Q5VZL5
LQLGYLYRCVQELRQ	XKR8	91	Q9H6D3
ERKFCYQQLPVTLRL	UNC79	941	Q9P2D8
PEARYYLRQIVLGCQ	PLK1	151	P53350
LRYPNCNIQRLGLEY	NLRP14	981	Q86W24