Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	intraciliary transport particle B binding	KIF3B KIF3A	1.75e-04	6	69	2	GO:0120170
GeneOntologyMolecularFunction	chromatin binding	TDRD3 DDX17 NSD2 NELFA ESR1 ING5 KDM3B HMGA1 KDM6B BAHCC1	2.14e-04	739	69	10	GO:0003682
GeneOntologyMolecularFunction	dioxygenase activity	ALKBH2 KDM3B KDM6B RSBN1L	3.69e-04	98	69	4	GO:0051213
GeneOntologyMolecularFunction	demethylase activity	ALKBH2 KDM3B KDM6B	4.73e-04	44	69	3	GO:0032451
GeneOntologyMolecularFunction	estrogen response element binding	ESR1 ESRRA	6.34e-04	11	69	2	GO:0034056
GeneOntologyMolecularFunction	microtubule binding	KIF3B TRAF3IP1 KIF26B CEP295NL APC2 KIF3A	6.80e-04	308	69	6	GO:0008017
GeneOntologyCellularComponent	kinesin II complex	KIF3B KIF3A	3.40e-05	3	71	2	GO:0016939
Domain	Oest_rcpt/oest-rel_rcp	ESR1 ESRRA	1.26e-04	5	67	2	IPR024178
Domain	MA3	EIF4G1 PDCD4	1.88e-04	6	67	2	SM00544
Domain	MA3	EIF4G1 PDCD4	1.88e-04	6	67	2	PF02847
Domain	MI	EIF4G1 PDCD4	1.88e-04	6	67	2	PS51366
Domain	Initiation_fac_eIF4g_MI	EIF4G1 PDCD4	1.88e-04	6	67	2	IPR003891
Domain	Kinesin-like_fam	KIF3B KIF26B KIF3A	4.91e-04	43	67	3	IPR027640
Domain	KINESIN_MOTOR_1	KIF3B KIF26B KIF3A	5.26e-04	44	67	3	PS00411
Domain	-	KIF3B KIF26B KIF3A	5.26e-04	44	67	3	3.40.850.10
Domain	Kinesin_motor_dom	KIF3B KIF26B KIF3A	5.26e-04	44	67	3	IPR001752
Domain	Kinesin	KIF3B KIF26B KIF3A	5.26e-04	44	67	3	PF00225
Domain	KINESIN_MOTOR_2	KIF3B KIF26B KIF3A	5.26e-04	44	67	3	PS50067
Domain	KISc	KIF3B KIF26B KIF3A	5.26e-04	44	67	3	SM00129
Domain	MIF4-like	EIF4G1 PDCD4	1.29e-03	15	67	2	IPR016021
Domain	-	EIF4G1 PDCD4	1.29e-03	15	67	2	1.25.40.180
Domain	AT_hook	CECR2 HMGA1	1.47e-03	16	67	2	PF02178
Domain	JmjC	KDM3B KDM6B	3.33e-03	24	67	2	PF02373
Domain	HMGI/Y_DNA-bd_CS	CECR2 HMGA1	5.51e-03	31	67	2	IPR000637
Domain	JMJC	KDM3B KDM6B	5.87e-03	32	67	2	PS51184
Domain	JmjC_dom	KDM3B KDM6B	5.87e-03	32	67	2	IPR003347
Domain	JmjC	KDM3B KDM6B	6.23e-03	33	67	2	SM00558
Domain	Kinesin_motor_CS	KIF3B KIF3A	9.50e-03	41	67	2	IPR019821
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SART1 SCAF1 STC2 NELFA ESRRA YLPM1 EIF4G1 RBM6 KDM3B BUD13 DAXX HMGA1 SAP30 ZMYM3 HDLBP	9.41e-11	774	75	15	15302935
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	USP36 SART1 SERBP1 DDX17 NSD2 YLPM1 EIF4G1 BYSL ANKRD11 RBM6 BUD13 HMGA1 LYAR SNRNP70 RSBN1L HDLBP	1.71e-10	954	75	16	36373674
Pubmed	Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation.	SART1 THAP4 KIF3B TRAF3IP1 NSD2 HMGA1 ROBO3 SNRNP70 KIF3A VCY	1.16e-09	305	75	10	21244100
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	SERBP1 DDX17 HNRNPUL2 G3BP2 EIF4G1 BYSL RBM6 SNRNP70 HDLBP	4.85e-09	258	75	9	37794589
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	SART1 TDRD3 SERBP1 DDX17 HNRNPUL2 NSD2 G3BP2 EIF4G1 BYSL RBM6 BUD13 LYAR SNRNP70	8.39e-09	759	75	13	35915203
Pubmed	ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.	SCAF1 SERBP1 DDX17 NSD2 ESR1 BYSL LYAR SNRNP70 ZMYM3	4.05e-08	330	75	9	33301849
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	USP36 SART1 TDRD3 SERBP1 G3BP2 ESRRA YLPM1 EIF4G1 DAXX HMGA1 AHNAK2 HDLBP	4.77e-08	724	75	12	36232890
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PHLDB3 SCAF1 TDRD3 SPRED2 NSD2 TMEM132A EIF4G1 ANKRD11 KDM3B MAP3K11 KDM6B SAP30 AHNAK2 BAHCC1	9.07e-08	1105	75	14	35748872
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	USP36 SCAF1 TDRD3 SERBP1 NSD2 ESR1 EIF4G1 BYSL ANKRD11 RBM6 BUD13 DAXX LYAR RSBN1L ZMYM3 HDLBP	9.92e-08	1497	75	16	31527615
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	USP36 SART1 SCAF1 DDX17 OGFR YLPM1 BYSL RBM6 ANP32E DAXX LYAR SNRNP70 RSBN1L	1.82e-07	989	75	13	36424410
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	USP36 SART1 SERBP1 DDX17 HNRNPUL2 G3BP2 EIF4G1 BYSL HMGA1 LYAR HDLBP	3.61e-07	711	75	11	33022573
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	SART1 SERBP1 DDX17 HNRNPUL2 G3BP2 EIF4G1 BYSL LYAR SNRNP70 RSBN1L HDLBP	3.71e-07	713	75	11	29802200
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	SART1 DDX17 HNRNPUL2 NSD2 CECR2 YLPM1 EIF4G1 RBM6 BUD13 HMGA1 LYAR SNRNP70 ZMYM3	5.05e-07	1082	75	13	38697112
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	USP36 SART1 THAP4 SCAF1 DDX17 NSD2 YLPM1 ING5 ANKRD11 HMGA1 LYAR SNRNP70 SAP30 ZMYM3	6.10e-07	1294	75	14	30804502
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	SART1 DDX17 EIF4G1 DAXX PDCD4 ZMYM3 AHNAK2 HDLBP	6.13e-07	332	75	8	32786267
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	USP36 SART1 SERBP1 DDX17 HNRNPUL2 YLPM1 EIF4G1 BYSL LYAR SNRNP70	7.08e-07	605	75	10	28977666
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	USP36 SART1 SCAF1 NSD2 CECR2 ESRRA ING5 BUD13 LYAR RSBN1L SAP30 ZMYM3 BAHCC1	7.14e-07	1116	75	13	31753913
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	USP36 TDRD3 SERBP1 DDX17 YLPM1 KDM3B ANP32E HMGA1 RSBN1L PDCD4 AHNAK2 HDLBP	7.25e-07	934	75	12	33916271
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	SART1 SERBP1 DDX17 NELFA G3BP2 EIF4G1 LYAR SNRNP70 PDCD4 HDLBP	8.21e-07	615	75	10	31048545
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SART1 CACNA1E TDRD3 KIF3B TRAF3IP1 HNRNPUL2 G3BP2 APC2 YLPM1 EIF4G1 KIF3A AGAP2	9.98e-07	963	75	12	28671696
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	SART1 TDRD3 SERBP1 DDX17 HNRNPUL2 G3BP2 YLPM1 RBM6 LYAR SNRNP70 HDLBP	1.24e-06	807	75	11	22681889
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	SERBP1 DDX17 G3BP2 YLPM1 EIF4G1 BYSL ANP32E LYAR KIF3A HDLBP SORCS1	1.27e-06	809	75	11	32129710
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	SERBP1 DDX17 HNRNPUL2 NELFA EIF4G1 RBM6 MAP3K11 SNRNP70 PDCD4	1.39e-06	503	75	9	16964243
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SART1 SERBP1 NSD2 YLPM1 EIF4G1 BYSL RBM6 SNRNP70 ZMYM3 HDLBP	1.41e-06	653	75	10	22586326
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	SERBP1 DDX17 HMGA1 SNRNP70 PDCD4 HDLBP	1.49e-06	163	75	6	22113938
Pubmed	The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3.	KIF3B MAP3K11 KIF3A	1.57e-06	11	75	3	9427749
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	SART1 SERBP1 HNRNPUL2 NSD2 NELFA YLPM1 EIF4G1 KDM3B ANP32E HMGA1 LYAR SAP30	1.71e-06	1014	75	12	32416067
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	SART1 SERBP1 DDX17 OGFR G3BP2 EIF4G1 BYSL ANP32E HMGA1 LYAR SNRNP70 PDCD4 AHNAK2 HDLBP	1.75e-06	1415	75	14	28515276
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	USP36 SART1 SCAF1 SERBP1 DDX17 HNRNPUL2 NSD2 G3BP2 EIF4G1 BYSL ANP32E LYAR SNRNP70 HDLBP	1.90e-06	1425	75	14	30948266
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	SART1 TDRD3 SERBP1 DDX17 HNRNPUL2 G3BP2 EIF4G1 BYSL LYAR SNRNP70	1.97e-06	678	75	10	30209976
Pubmed	The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.	SCAF1 SERBP1 DDX17 HNRNPUL2 NELFA BYSL HMGA1 RSBN1L	3.34e-06	417	75	8	36537216
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	USP36 DDX17 KIF3B G3BP2 BYSL RBM6 HMGA1 LYAR SNRNP70 KIF3A	3.48e-06	723	75	10	34133714
Pubmed	siRNA silencing of estrogen receptor-α expression specifically in medial preoptic area neurons abolishes maternal care in female mice.	ESR1 ESRRA	4.59e-06	2	75	2	22988120
Pubmed	C2CD4A/B variants in the predisposition of lung cancer in the Chinese Han population.	C2CD4B C2CD4A	4.59e-06	2	75	2	35212842
Pubmed	Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis.	C2CD4B C2CD4A	4.59e-06	2	75	2	33492421
Pubmed	The functional interaction between HMGA1 and the estrogen receptor requires either the N- or the C-terminal domain of the receptor.	ESR1 HMGA1	4.59e-06	2	75	2	14960313
Pubmed	Cholinergic neurons in the basal forebrain of aged female mice.	ESR1 CHAT	4.59e-06	2	75	2	15353224
Pubmed	A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression.	C2CD4B C2CD4A	4.59e-06	2	75	2	29625024
Pubmed	Photoreceptor localization of the KIF3A and KIF3B subunits of the heterotrimeric microtubule motor kinesin II in vertebrate retina.	KIF3B KIF3A	4.59e-06	2	75	2	10548469
Pubmed	Overexpression, purification, and crystal structure of native ER alpha LBD.	ESR1 ESRRA	4.59e-06	2	75	2	11437591
Pubmed	Torque generation of kinesin motors is governed by the stability of the neck domain.	KIF3B KIF3A	4.59e-06	2	75	2	22541555
Pubmed	Increased adipose tissue in male and female estrogen receptor-alpha knockout mice.	ESR1 ESRRA	4.59e-06	2	75	2	11070086
Pubmed	Genomic amplification upregulates estrogen-related receptor alpha and its depletion inhibits oral squamous cell carcinoma tumors in vivo.	ESR1 ESRRA	4.59e-06	2	75	2	26639757
Pubmed	Kinesin-2 KIF3AB exhibits novel ATPase characteristics.	KIF3B KIF3A	4.59e-06	2	75	2	25122755
Pubmed	[Genetic determination of Wolf-Hirschhorn syndrome ].	NSD2 NELFA	4.59e-06	2	75	2	12715353
Pubmed	The two motor domains of KIF3A/B coordinate for processive motility and move at different speeds.	KIF3B KIF3A	4.59e-06	2	75	2	15345558
Pubmed	USP36 promotes tumorigenesis and tamoxifen resistance in breast cancer by deubiquitinating and stabilizing ERα.	USP36 ESR1	4.59e-06	2	75	2	39215346
Pubmed	Potentiation of ICI182,780 (Fulvestrant)-induced estrogen receptor-alpha degradation by the estrogen receptor-related receptor-alpha inverse agonist XCT790.	ESR1 ESRRA	4.59e-06	2	75	2	17631492
Pubmed	Reprogramming of the ERRα and ERα target gene landscape triggers tamoxifen resistance in breast cancer.	ESR1 ESRRA	4.59e-06	2	75	2	25643697
Pubmed	A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/β-catenin signaling.	ESR1 RSPO1	4.59e-06	2	75	2	32749219
Pubmed	An estrogen receptor (ER)alpha deoxyribonucleic acid-binding domain knock-in mutation provides evidence for nonclassical ER pathway signaling in vivo.	ESR1 ESRRA	4.59e-06	2	75	2	12351685
Pubmed	A transcript map of the newly defined 165 kb Wolf-Hirschhorn syndrome critical region.	NSD2 NELFA	4.59e-06	2	75	2	9063753
Pubmed	RH70, a bidirectional RNA helicase, co-purifies with U1snRNP.	DDX17 SNRNP70	4.59e-06	2	75	2	12193588
Pubmed	KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport.	KIF3B KIF3A	4.59e-06	2	75	2	7559760
Pubmed	The enhanced expression of estrogen-related receptor α in human bladder cancer tissues and the effects of estrogen-related receptor α knockdown on bladder cancer cells.	ESR1 ESRRA	4.59e-06	2	75	2	30977157
Pubmed	Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.	SART1 SERBP1 G3BP2 EIF4G1 SNRNP70	4.98e-06	114	75	5	31553912
Pubmed	EIF3H Orchestrates Hippo Pathway-Mediated Oncogenesis via Catalytic Control of YAP Stability.	SERBP1 EIF4G1 LYAR HDLBP	6.26e-06	55	75	4	32269044
Pubmed	Arginine methylation of SARS-Cov-2 nucleocapsid protein regulates RNA binding, its ability to suppress stress granule formation, and viral replication.	TDRD3 SERBP1 HNRNPUL2 G3BP2 LYAR	6.66e-06	121	75	5	34029587
Pubmed	Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.	SART1 SERBP1 DDX17 HNRNPUL2 G3BP2 EIF4G1	9.04e-06	223	75	6	20020773
Pubmed	Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.	SERBP1 ESR1 ESRRA DAXX TNNI3	1.06e-05	133	75	5	15604093
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	USP36 SERBP1 NSD2 BYSL DAXX LYAR SNRNP70	1.07e-05	349	75	7	25665578
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	USP36 SART1 SCAF1 EIF4G1 BUD13 HMGA1 SNRNP70	1.33e-05	361	75	7	26167880
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	SART1 SERBP1 DDX17 NELFA YLPM1 KDM3B ANP32E SNRNP70	1.36e-05	506	75	8	30890647
Pubmed	Expression of the estrogen-related receptor 1 (ERR-1) orphan receptor during mouse development.	ESR1 ESRRA	1.37e-05	3	75	2	9256346
Pubmed	A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.	C2CD4B C2CD4A	1.37e-05	3	75	2	20818381
Pubmed	The Rip11/Rab11-FIP5 and kinesin II complex regulates endocytic protein recycling.	KIF3B KIF3A	1.37e-05	3	75	2	18957512
Pubmed	A genome-wide association study confirms previously reported loci for type 2 diabetes in Han Chinese.	C2CD4B C2CD4A	1.37e-05	3	75	2	21799836
Pubmed	Structural basis for translational inhibition by the tumour suppressor Pdcd4.	EIF4G1 PDCD4	1.37e-05	3	75	2	19153607
Pubmed	Kinesin-2 KIF3AC and KIF3AB Can Drive Long-Range Transport along Microtubules.	KIF3B KIF3A	1.37e-05	3	75	2	26445448
Pubmed	Heterodimerization of Kinesin-2 KIF3AB Modulates Entry into the Processive Run.	KIF3B KIF3A	1.37e-05	3	75	2	27637334
Pubmed	Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice.	C2CD4B C2CD4A	1.37e-05	3	75	2	27329800
Pubmed	Estrogen induces estrogen-related receptor alpha gene expression and chromatin structural changes in estrogen receptor (ER)-positive and ER-negative breast cancer cells.	ESR1 ESRRA	1.37e-05	3	75	2	18174157
Pubmed	PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains.	EIF4G1 PDCD4	1.37e-05	3	75	2	18296639
Pubmed	Estrogen receptor alpha and estrogen receptor-related receptor alpha1 compete for binding and coactivator.	ESR1 ESRRA	1.37e-05	3	75	2	11165056
Pubmed	Estrogen-related receptor alpha 1 functionally binds as a monomer to extended half-site sequences including ones contained within estrogen-response elements.	ESR1 ESRRA	1.37e-05	3	75	2	9058380
Pubmed	Estradiol mediates vasculoprotection via ERRα-dependent regulation of lipid and ROS metabolism in the endothelium.	ESR1 ESRRA	1.37e-05	3	75	2	26271712
Pubmed	Expression of KIF3C kinesin during neural development and in vitro neuronal differentiation.	KIF3B KIF3A	1.37e-05	3	75	2	11331403
Pubmed	Estrogen Receptor α (ERα) and Estrogen Related Receptor α (ERRα) are both transcriptional regulators of the Runx2-I isoform.	ESR1 ESRRA	1.37e-05	3	75	2	23403054
Pubmed	Association of the testis-specific TRIM/RBCC protein RNF33/TRIM60 with the cytoplasmic motor proteins KIF3A and KIF3B.	KIF3B KIF3A	1.37e-05	3	75	2	21909995
Pubmed	The DEAD-box protein p72 regulates ERalpha-/oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERalpha-positive breast cancer.	DDX17 ESR1	1.37e-05	3	75	2	19718048
Pubmed	Estrogen-related receptor alpha expression and function is associated with the transcriptional coregulator AIB1 in breast carcinoma.	ESR1 ESRRA	1.37e-05	3	75	2	19491275
Pubmed	Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load.	KIF3B KIF3A	1.37e-05	3	75	2	28761002
Pubmed	Communication between the ERRalpha homodimer interface and the PGC-1alpha binding surface via the helix 8-9 loop.	ESR1 ESRRA	1.37e-05	3	75	2	18441008
Pubmed	Kinesin-2 and photoreceptor cell death: requirement of motor subunits.	KIF3B KIF3A	1.37e-05	3	75	2	16337628
Pubmed	A novel gene family induced by acute inflammation in endothelial cells.	C2CD4B C2CD4A	1.37e-05	3	75	2	15527968
Pubmed	Nuclear insulin receptor substrate 1 interacts with estrogen receptor alpha at ERE promoters.	ESR1 ESRRA	1.37e-05	3	75	2	15318176
Pubmed	Chicken ovalbumin upstream promoter-transcription factor interacts with estrogen receptor, binds to estrogen response elements and half-sites, and inhibits estrogen-induced gene expression.	ESR1 ESRRA	1.37e-05	3	75	2	9395481
Pubmed	Structural basis for inhibition of translation by the tumor suppressor Pdcd4.	EIF4G1 PDCD4	1.37e-05	3	75	2	17060447
Pubmed	Role of the kinesin-2 family protein, KIF3, during mitosis.	KIF3B KIF3A	1.37e-05	3	75	2	16298999
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	SART1 SERBP1 DDX17 HNRNPUL2 G3BP2 EIF4G1 BYSL BUD13 LYAR RSBN1L PDCD4 HDLBP	1.50e-05	1257	75	12	36526897
Pubmed	Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.	DDX17 ESR1 G3BP2 EIF4G1 BUD13 LYAR	1.54e-05	245	75	6	21182205
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	SCAF1 G3BP2 BYSL BUD13 LYAR SNRNP70	1.77e-05	251	75	6	28077445
Pubmed	Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.	ESR1 EIF4G1 BYSL RBM6 KDM3B	1.83e-05	149	75	5	25231870
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	THAP4 SPRED2 TRAF3IP1 APC2 YLPM1 EIF4G1 MAP3K11 KDM6B SNRNP70 RSBN1L KIF3A AGAP2	1.87e-05	1285	75	12	35914814
Pubmed	Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics.	SART1 DDX17 EIF4G1 BYSL LYAR SNRNP70 HDLBP	1.97e-05	384	75	7	31059266
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	SART1 DDX17 G3BP2 YLPM1 SNRNP70	2.14e-05	154	75	5	16055720
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	SART1 THAP4 DDX17 NELFA G3BP2 KDM3B ANP32E HMGA1 SNRNP70 ZMYM3 HDLBP	2.38e-05	1103	75	11	34189442
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	SART1 SERBP1 DDX17 HNRNPUL2 G3BP2 EIF4G1 BYSL PDCD4	2.51e-05	551	75	8	34728620
Pubmed	Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.	SART1 TDRD3 OGFR EIF4G1 ANP32E HMGA1 SNRNP70	2.68e-05	403	75	7	35253629
Pubmed	Tumor suppressor protein Pdcd4 interacts with Daxx and modulates the stability of Daxx and the Hipk2-dependent phosphorylation of p53 at serine 46.	DAXX PDCD4	2.75e-05	4	75	2	23536002
Interaction	SSRP1 interactions	USP36 SART1 SCAF1 DDX17 HNRNPUL2 NELFA ESR1 YLPM1 ING5 ANKRD11 DAXX LYAR KDM6B SNRNP70 HDLBP	2.75e-08	685	75	15	int:SSRP1
Interaction	CHD4 interactions	USP36 SART1 SERBP1 DDX17 HNRNPUL2 NSD2 ESR1 YLPM1 EIF4G1 BYSL DAXX HMGA1 LYAR SNRNP70 SAP30 ZMYM3 HDLBP	4.54e-08	938	75	17	int:CHD4
Interaction	DHX8 interactions	USP36 SART1 SCAF1 SERBP1 ESR1 YLPM1 RBM6 BUD13 SNRNP70 RSBN1L	1.26e-07	292	75	10	int:DHX8
Interaction	RBM8A interactions	SART1 TDRD3 SERBP1 ESR1 G3BP2 YLPM1 EIF4G1 HMGA1 LYAR SNRNP70 PDCD4 HDLBP	1.66e-07	473	75	12	int:RBM8A
Interaction	RBM42 interactions	SART1 SERBP1 HNRNPUL2 ESR1 YLPM1 EIF4G1 LYAR SNRNP70 PDCD4 HDLBP	4.02e-07	331	75	10	int:RBM42
Interaction	HECTD1 interactions	SART1 TDRD3 SERBP1 DDX17 HNRNPUL2 NSD2 ESR1 G3BP2 EIF4G1 BYSL ANKRD11 RBM6 BUD13 LYAR SNRNP70 PDCD4	5.23e-07	984	75	16	int:HECTD1
Interaction	NHP2 interactions	USP36 SERBP1 NSD2 ESR1 DAXX LYAR HDLBP	5.74e-07	131	75	7	int:NHP2
Interaction	SMC5 interactions	USP36 SART1 SERBP1 DDX17 NSD2 YLPM1 EIF4G1 BYSL ANKRD11 RBM6 BUD13 HMGA1 LYAR SNRNP70 RSBN1L HDLBP	6.48e-07	1000	75	16	int:SMC5
Interaction	CCDC137 interactions	USP36 SERBP1 NSD2 ESR1 BUD13 LYAR SNRNP70 RSBN1L	7.81e-07	200	75	8	int:CCDC137
Interaction	DDX23 interactions	USP36 SART1 SCAF1 ANKRD11 RBM6 ANP32E BUD13 LYAR SNRNP70 RSBN1L HDLBP	1.55e-06	480	75	11	int:DDX23
Interaction	H2BC21 interactions	CACNA1E SERBP1 NSD2 ESR1 ING5 ANP32E DAXX HMGA1 KDM6B PDCD4 SAP30 ZMYM3 BAHCC1	1.57e-06	696	75	13	int:H2BC21
Interaction	GPATCH4 interactions	USP36 NSD2 ESR1 BUD13 DAXX LYAR SNRNP70 HDLBP	2.38e-06	232	75	8	int:GPATCH4
Interaction	RPS16 interactions	USP36 SERBP1 NSD2 ESR1 G3BP2 EIF4G1 BYSL DAXX LYAR SNRNP70 RSBN1L PDCD4 HDLBP	2.42e-06	724	75	13	int:RPS16
Interaction	PSPC1 interactions	SART1 SERBP1 DDX17 HNRNPUL2 ESR1 YLPM1 EIF4G1 LYAR RSBN1L PDCD4 HDLBP	3.05e-06	515	75	11	int:PSPC1
Interaction	LARP4B interactions	SCAF1 TDRD3 SERBP1 NSD2 ESR1 G3BP2 SNRNP70 HDLBP	3.05e-06	240	75	8	int:LARP4B
Interaction	FTSJ3 interactions	USP36 SART1 SERBP1 NSD2 ESR1 BYSL RBM6 LYAR SNRNP70 HDLBP	3.59e-06	422	75	10	int:FTSJ3
Interaction	SNRNP40 interactions	USP36 SART1 SCAF1 DDX17 HNRNPUL2 NSD2 G3BP2 RBM6 BUD13 SNRNP70 RSBN1L HDLBP	3.80e-06	637	75	12	int:SNRNP40
Interaction	CHD3 interactions	USP36 SART1 SERBP1 DDX17 HNRNPUL2 YLPM1 EIF4G1 BYSL LYAR SNRNP70 SAP30 ZMYM3 HDLBP	3.94e-06	757	75	13	int:CHD3
Interaction	SRP9 interactions	SERBP1 HNRNPUL2 ESR1 EIF4G1 ANP32E LYAR SNRNP70 RSBN1L PDCD4 HDLBP	3.98e-06	427	75	10	int:SRP9
Interaction	RSBN1L interactions	USP36 ESR1 LYAR SNRNP70 RSBN1L HDLBP	4.21e-06	114	75	6	int:RSBN1L
Interaction	FXR2 interactions	TDRD3 SERBP1 DDX17 NKD2 CECR2 G3BP2 EIF4G1 BYSL SNRNP70 HDLBP	4.24e-06	430	75	10	int:FXR2
Interaction	NIFK interactions	USP36 SCAF1 SERBP1 ESR1 ANKRD11 ANP32E BUD13 LYAR SNRNP70 HDLBP	4.32e-06	431	75	10	int:NIFK
Interaction	DHX57 interactions	USP36 TDRD3 SERBP1 ESR1 G3BP2 LYAR SNRNP70 HDLBP	4.38e-06	252	75	8	int:DHX57
Interaction	ILF3 interactions	USP36 SART1 SERBP1 DDX17 HNRNPUL2 NSD2 ESR1 G3BP2 YLPM1 RBM6 BUD13 SNRNP70 PDCD4 HDLBP	4.76e-06	896	75	14	int:ILF3
Interaction	TOP3B interactions	PHLDB3 SCAF1 TDRD3 SPRED2 NSD2 G3BP2 TMEM132A EIF4G1 BYSL ANKRD11 KDM3B MAP3K11 LYAR KDM6B SAP30 AHNAK2 BAHCC1 HDLBP	5.37e-06	1470	75	18	int:TOP3B
Interaction	H2BC9 interactions	PRSS35 SCAF1 TDRD3 SERBP1 TRAF3IP1 CEP295NL YLPM1 ING5 HMGA1 PDCD4	5.84e-06	446	75	10	int:H2BC9
Interaction	ZBTB2 interactions	SCAF1 SERBP1 DDX17 NSD2 ESR1 BYSL DAXX LYAR SNRNP70 ZMYM3	6.32e-06	450	75	10	int:ZBTB2
Interaction	NPM1 interactions	USP36 SCAF1 TDRD3 SERBP1 NSD2 ESR1 G3BP2 EIF4G1 BYSL BUD13 HMGA1 LYAR SNRNP70 RSBN1L PDCD4 AHNAK2	6.95e-06	1201	75	16	int:NPM1
Interaction	PRMT1 interactions	SART1 TDRD3 SERBP1 DDX17 HNRNPUL2 ESR1 G3BP2 YLPM1 EIF4G1 BYSL DAXX SNRNP70 PDCD4 HDLBP	7.20e-06	929	75	14	int:PRMT1
Interaction	FXR1 interactions	TDRD3 SERBP1 NKD2 HNRNPUL2 CECR2 ESR1 G3BP2 APC2 EIF4G1 BYSL SNRNP70 HDLBP	7.26e-06	679	75	12	int:FXR1
Interaction	SRP14 interactions	USP36 NSD2 ESR1 G3BP2 EIF4G1 BUD13 LYAR SNRNP70 HDLBP	8.51e-06	366	75	9	int:SRP14
Interaction	MYCN interactions	USP36 PRSS35 SART1 SCAF1 SERBP1 DDX17 HNRNPUL2 G3BP2 BYSL RBM6 BUD13 DAXX HMGA1 LYAR SNRNP70 SAP30 ZMYM3	8.97e-06	1373	75	17	int:MYCN
Interaction	TOP1 interactions	USP36 SART1 SCAF1 DDX17 HNRNPUL2 NSD2 ESR1 YLPM1 RBM6 BUD13 SNRNP70 HDLBP	9.32e-06	696	75	12	int:TOP1
Interaction	LYAR interactions	USP36 NSD2 ESR1 G3BP2 BUD13 LYAR SNRNP70 RSBN1L HDLBP	9.91e-06	373	75	9	int:LYAR
Interaction	SRSF5 interactions	SART1 SCAF1 SERBP1 NSD2 ESR1 BUD13 LYAR SNRNP70 RSBN1L HDLBP	9.95e-06	474	75	10	int:SRSF5
Interaction	SRP68 interactions	USP36 SERBP1 ESR1 G3BP2 EIF4G1 KDM3B LYAR PDCD4 HDLBP	1.17e-05	381	75	9	int:SRP68
Interaction	USP10 interactions	TDRD3 SERBP1 ESR1 G3BP2 EIF4G1 HMGA1 SNRNP70 HDLBP	1.22e-05	290	75	8	int:USP10
Interaction	PURA interactions	USP36 SERBP1 ESR1 EIF4G1 LYAR SNRNP70 PDCD4 HDLBP	1.25e-05	291	75	8	int:PURA
Interaction	DDX21 interactions	USP36 SART1 SERBP1 DDX17 HNRNPUL2 NSD2 ESR1 G3BP2 YLPM1 EIF4G1 LYAR SNRNP70	1.27e-05	718	75	12	int:DDX21
Interaction	FAU interactions	USP36 SERBP1 NSD2 G3BP2 BYSL SNRNP70 HDLBP	1.27e-05	209	75	7	int:FAU
Interaction	RPS3 interactions	USP36 SCAF1 SERBP1 ESR1 G3BP2 EIF4G1 BYSL DAXX LYAR SNRNP70 RSBN1L HDLBP	1.33e-05	721	75	12	int:RPS3
Interaction	HDAC2 interactions	USP36 SERBP1 DDX17 NSD2 NELFA ESR1 G3BP2 DAXX HMGA1 SNRNP70 SAP30 ZMYM3 AHNAK2	1.65e-05	865	75	13	int:HDAC2
Interaction	SIRT7 interactions	SART1 SERBP1 NSD2 ESR1 YLPM1 EIF4G1 BYSL RBM6 LYAR SNRNP70 ZMYM3 HDLBP	1.81e-05	744	75	12	int:SIRT7
Interaction	DROSHA interactions	USP36 HNRNPUL2 ESR1 YLPM1 HDLBP	1.82e-05	87	75	5	int:DROSHA
Interaction	RPS6 interactions	USP36 TDRD3 SERBP1 NSD2 ESR1 G3BP2 EIF4G1 BYSL BUD13 DAXX LYAR SNRNP70 RSBN1L	1.84e-05	874	75	13	int:RPS6
Interaction	KAT6A interactions	SCAF1 SERBP1 DDX17 HNRNPUL2 NELFA ESR1 ING5 BYSL HMGA1 RSBN1L	1.87e-05	510	75	10	int:KAT6A
Interaction	NOP14 interactions	USP36 DDX17 ESR1 BYSL DAXX HMGA1 SNRNP70	1.88e-05	222	75	7	int:NOP14
Interaction	CAAP1 interactions	SERBP1 ESR1 ING5 SNRNP70	1.96e-05	43	75	4	int:CAAP1
Interaction	ATXN2 interactions	TDRD3 SERBP1 DDX17 HNRNPUL2 ESR1 G3BP2 EIF4G1 SNRNP70	2.07e-05	312	75	8	int:ATXN2
Interaction	G3BP2 interactions	TDRD3 SERBP1 ESR1 G3BP2 EIF4G1 ANP32E LYAR SNRNP70 PDCD4 HDLBP	2.14e-05	518	75	10	int:G3BP2
Interaction	FUS interactions	SART1 TDRD3 SERBP1 DDX17 NKD2 HNRNPUL2 ESR1 ESRRA YLPM1 RBM6 C6 SNRNP70	2.15e-05	757	75	12	int:FUS
Interaction	TOP2A interactions	USP36 SERBP1 HNRNPUL2 NSD2 ESR1 G3BP2 EIF4G1 DAXX HMGA1 SNRNP70	2.21e-05	520	75	10	int:TOP2A
Interaction	SMARCA5 interactions	USP36 NSD2 CECR2 ESR1 DAXX HMGA1 SNRNP70 SAP30 HDLBP	2.31e-05	415	75	9	int:SMARCA5
Interaction	OBSL1 interactions	SART1 SCAF1 DDX17 HNRNPUL2 CECR2 G3BP2 YLPM1 BYSL DAXX HMGA1 SNRNP70 RSBN1L HDLBP	2.56e-05	902	75	13	int:OBSL1
Interaction	RPS24 interactions	USP36 TDRD3 SERBP1 ESR1 G3BP2 BYSL ANKRD11 ANP32E LYAR SNRNP70	2.56e-05	529	75	10	int:RPS24
Interaction	MKI67 interactions	USP36 HNRNPUL2 NSD2 ESR1 G3BP2 YLPM1 EIF4G1 DAXX LYAR SNRNP70 HDLBP	2.64e-05	648	75	11	int:MKI67
Interaction	ABT1 interactions	USP36 SCAF1 NSD2 BYSL BUD13 LYAR RSBN1L SAP30 HDLBP	2.68e-05	423	75	9	int:ABT1
Interaction	TMA16 interactions	SERBP1 ESR1 LYAR SNRNP70 HDLBP	2.78e-05	95	75	5	int:TMA16
Interaction	FMR1 interactions	TDRD3 SERBP1 CECR2 ESR1 G3BP2 APC2 EIF4G1 SNRNP70 AGAP2 HDLBP	2.86e-05	536	75	10	int:FMR1
Interaction	TFIP11 interactions	SART1 DDX17 HNRNPUL2 ESR1 BYSL ANKRD11 DAXX SNRNP70 HDLBP	2.89e-05	427	75	9	int:TFIP11
Interaction	RPL26L1 interactions	HNRNPUL2 G3BP2 BYSL BUD13 DAXX LYAR SNRNP70 RSBN1L HDLBP	3.10e-05	431	75	9	int:RPL26L1
Interaction	UPF2 interactions	SERBP1 ESR1 EIF4G1 HMGA1 SNRNP70 HDLBP	3.13e-05	162	75	6	int:UPF2
Interaction	DHX9 interactions	USP36 SART1 TDRD3 SERBP1 DDX17 HNRNPUL2 ESR1 G3BP2 LYAR SNRNP70 HDLBP	3.20e-05	662	75	11	int:DHX9
Interaction	SRP72 interactions	USP36 SERBP1 ESR1 G3BP2 EIF4G1 LYAR PDCD4 HDLBP	3.29e-05	333	75	8	int:SRP72
Interaction	DDX18 interactions	USP36 SERBP1 ESR1 G3BP2 BYSL LYAR SNRNP70 HDLBP	3.36e-05	334	75	8	int:DDX18
Interaction	SRP19 interactions	SERBP1 ESR1 G3BP2 EIF4G1 LYAR PDCD4 HDLBP	3.45e-05	244	75	7	int:SRP19
Interaction	NCL interactions	USP36 SART1 SERBP1 DDX17 NSD2 ESR1 G3BP2 BYSL DAXX HMGA1 LYAR SNRNP70	3.60e-05	798	75	12	int:NCL
Interaction	H2AC11 interactions	SCAF1 SERBP1 NSD2 ANP32E HMGA1 SNRNP70 AHNAK2	3.82e-05	248	75	7	int:H2AC11
Interaction	ZNF330 interactions	USP36 NSD2 BYSL ANKRD11 ANP32E HMGA1 LYAR RSBN1L ZMYM3	4.05e-05	446	75	9	int:ZNF330
Interaction	WDR5 interactions	USP36 SART1 SERBP1 DDX17 HNRNPUL2 ESR1 G3BP2 EIF4G1 BYSL HMGA1 LYAR KDM6B SAP30 HDLBP	4.77e-05	1101	75	14	int:WDR5
Interaction	TEX10 interactions	USP36 SERBP1 ESR1 C2CD4A SNRNP70 HDLBP	4.82e-05	175	75	6	int:TEX10
Interaction	SLX4 interactions	USP36 SART1 SERBP1 DDX17 NKD2 NELFA RBM6 KDM3B DAXX HDLBP	4.95e-05	572	75	10	int:SLX4
Interaction	H2BC8 interactions	NSD2 NELFA ESR1 BYSL ANP32E BUD13 HMGA1 LYAR PDCD4 ZMYM3	5.25e-05	576	75	10	int:H2BC8
Interaction	SMARCA4 interactions	USP36 NSD2 ESR1 BYSL HMGA1 KDM6B SNRNP70 SAP30 HDLBP	5.32e-05	462	75	9	int:SMARCA4
Interaction	NFX1 interactions	SART1 DDX17 ESR1 APC2 EIF4G1 BYSL LYAR SNRNP70 HDLBP	5.68e-05	466	75	9	int:NFX1
Interaction	WDR77 interactions	SERBP1 HNRNPUL2 NSD2 ESR1 G3BP2 YLPM1 KDM6B PDCD4	5.82e-05	361	75	8	int:WDR77
Interaction	WWP2 interactions	SART1 SERBP1 DDX17 NELFA G3BP2 YLPM1 TMEM132A EIF4G1 LYAR SNRNP70 PDCD4 HDLBP	5.92e-05	840	75	12	int:WWP2
Interaction	KIFAP3 interactions	SART1 KIF3B MAP3K11 BUD13 KIF3A	6.14e-05	112	75	5	int:KIFAP3
Interaction	PRMT5 interactions	SART1 SERBP1 ESR1 G3BP2 ING5 KDM3B KDM6B SNRNP70 PDCD4	6.17e-05	471	75	9	int:PRMT5
Interaction	SRPK2 interactions	USP36 SART1 SCAF1 HNRNPUL2 ESR1 EIF4G1 BUD13 HMGA1 LYAR SNRNP70 HDLBP	6.59e-05	717	75	11	int:SRPK2
Interaction	RBM28 interactions	USP36 SART1 DDX17 ESR1 DAXX LYAR SNRNP70 HDLBP	6.66e-05	368	75	8	int:RBM28
Interaction	SYNCRIP interactions	TDRD3 SERBP1 DDX17 HNRNPUL2 ESR1 G3BP2 BYSL ANKRD11 HMGA1 SNRNP70 HDLBP	6.93e-05	721	75	11	int:SYNCRIP
Interaction	ANP32E interactions	SERBP1 NSD2 ESR1 G3BP2 ANP32E	6.96e-05	115	75	5	int:ANP32E
Interaction	EFTUD2 interactions	SART1 SERBP1 DDX17 ESR1 G3BP2 EIF4G1 BYSL RBM6 ANP32E HMGA1 LYAR SNRNP70 PDCD4 SAP30 AHNAK2 HDLBP	6.96e-05	1449	75	16	int:EFTUD2
Interaction	H2AZ1 interactions	USP36 NELFA ESR1 ING5 ANP32E HMGA1 SAP30 ZMYM3	7.04e-05	371	75	8	int:H2AZ1
Interaction	DDX10 interactions	USP36 SERBP1 ESR1 G3BP2 BYSL LYAR	7.62e-05	190	75	6	int:DDX10
Interaction	ZNF280C interactions	SERBP1 NSD2 DAXX HMGA1	7.86e-05	61	75	4	int:ZNF280C
Interaction	RPL5 interactions	USP36 SERBP1 HNRNPUL2 ESR1 G3BP2 EIF4G1 LYAR SNRNP70 RSBN1L PDCD4	8.01e-05	606	75	10	int:RPL5
Interaction	ZC3HAV1 interactions	USP36 TDRD3 SERBP1 NSD2 ESR1 G3BP2 DAXX LYAR SNRNP70 HDLBP	8.01e-05	606	75	10	int:ZC3HAV1
Interaction	KRR1 interactions	USP36 SERBP1 NSD2 ESR1 BYSL DAXX SNRNP70 HDLBP	8.17e-05	379	75	8	int:KRR1
Interaction	ADARB1 interactions	USP36 SCAF1 SERBP1 NSD2 BUD13 LYAR SNRNP70 RSBN1L HDLBP	8.22e-05	489	75	9	int:ADARB1
Interaction	POLR1G interactions	USP36 NSD2 ESR1 ANKRD11 ANP32E BUD13 LYAR RSBN1L ZMYM3	8.22e-05	489	75	9	int:POLR1G
Interaction	PARP1 interactions	USP36 SART1 SCAF1 NSD2 CECR2 ESR1 BYSL ANP32E DAXX HMGA1 LYAR RSBN1L SAP30 ZMYM3 HDLBP	8.58e-05	1316	75	15	int:PARP1
Interaction	EIF3H interactions	SERBP1 ESR1 G3BP2 EIF4G1 LYAR PDCD4 HDLBP	8.59e-05	282	75	7	int:EIF3H
Interaction	RPL28 interactions	USP36 SCAF1 TDRD3 SERBP1 NSD2 ESR1 G3BP2 BUD13 SNRNP70	8.88e-05	494	75	9	int:RPL28
Interaction	DRG1 interactions	SERBP1 ESR1 G3BP2 EIF4G1 LYAR SNRNP70 PDCD4 HDLBP	9.62e-05	388	75	8	int:DRG1
Interaction	MEN1 interactions	SART1 DDX17 ESR1 G3BP2 ESRRA YLPM1 EIF4G1 KDM3B DAXX LYAR SNRNP70 RSBN1L ZMYM3	9.86e-05	1029	75	13	int:MEN1
Interaction	GTPBP1 interactions	TDRD3 SERBP1 SNRNP70 KIF3A HDLBP	9.95e-05	124	75	5	int:GTPBP1
Interaction	CMSS1 interactions	USP36 ESR1 DAXX SNRNP70 HDLBP	9.95e-05	124	75	5	int:CMSS1
Interaction	RPL37A interactions	USP36 SART1 SERBP1 NSD2 ESR1 BUD13 LYAR SNRNP70	1.01e-04	391	75	8	int:RPL37A
Cytoband	2q37.3	THAP4 TRAF3IP1 ING5 HDLBP	8.12e-06	77	75	4	2q37.3
Cytoband	4p16.3	NSD2 NELFA LYAR	3.76e-04	85	75	3	4p16.3
Cytoband	Ensembl 112 genes in cytogenetic band chr2q37	THAP4 TRAF3IP1 ING5 HDLBP	5.29e-04	226	75	4	chr2q37
Cytoband	12q14.1	AVIL AGAP2	9.68e-04	28	75	2	12q14.1
Cytoband	15q22.2	C2CD4B C2CD4A	1.04e-03	29	75	2	15q22.2
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF3B KIF26B KIF3A	2.31e-04	46	47	3	622
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM3B KDM6B	1.76e-03	24	47	2	485
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000	PRSS35 COL23A1 STC2 ESR1 G3BP2 EIF4G1 ANKRD11 KDM6B RSPO1 ADCY5 C4orf54 KIF3A AHNAK2	3.36e-06	797	74	13	gudmap_developingGonad_P2_epididymis_1000
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#1_top-relative-expression-ranked_1000	PRSS35 TRANK1 TNNI3 CCDC171 ZMYM3	9.92e-06	82	74	5	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k1_1000
CoexpressionAtlas	dev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_200	PRSS35 TRANK1 STC2 TNNI3 CCDC171 ZMYM3	2.85e-05	170	74	6	gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_200
CoexpressionAtlas	dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_500	PRSS35 TRANK1 TNNI3 CCDC171	3.77e-05	54	74	4	gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k1_500
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_1000	PRSS35 TRANK1 TNNI3 CCDC171 ZMYM3	5.11e-05	115	74	5	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k4_1000
CoexpressionAtlas	dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_1000	PRSS35 TRANK1 TNNI3 CCDC171 ZMYM3	5.11e-05	115	74	5	gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k4_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_500	PRSS35 TRANK1 STC2 CCDC171	9.90e-05	69	74	4	gudmap_dev gonad_e11.5_M_GonMes_Sma_k4_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500_k-means-cluster#1	STC2 CECR2 ROBO3 LYAR	9.90e-05	69	74	4	Facebase_RNAseq_e8.5_Floor Plate_500_K1
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500	PRSS35 TRANK1 STC2 CCDC171	1.17e-04	72	74	4	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k1_500
CoexpressionAtlas	DevelopingKidney_e11.5_metaneph mesench_emap-3843_top-relative-expression-ranked_1000	COL23A1 SERBP1 KIF26B ALKBH2 NSD2 BYSL ANKRD11 DAXX RSPO1 KIF3A BAHCC1	1.65e-04	850	74	11	gudmap_developingKidney_e11.5_metaneph mesench_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_1000	PRSS35 TRANK1 STC2 CCDC171 ZMYM3	2.09e-04	155	74	5	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k1_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#1_top-relative-expression-ranked_1000	PRSS35 TRANK1 STC2 CCDC171 ZMYM3	2.15e-04	156	74	5	gudmap_dev gonad_e11.5_M_GonMes_Sma_k1_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1	SART1 SERBP1 TRAF3IP1 ANKRD11 RBM6 LYAR RSPO1 SAP30	2.24e-04	469	74	8	Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlas	dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_1000	PRSS35 TRANK1 STC2 CCDC171 ZMYM3	3.20e-04	170	74	5	gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k4_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500	PRSS35 STC2 CECR2 APC2 ROBO3 LYAR CCDC171 RAX	3.23e-04	495	74	8	Facebase_RNAseq_e8.5_Floor Plate_500
CoexpressionAtlas	DevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#3_top-relative-expression-ranked_500	PRSS35 COL23A1 TRANK1 TNNI3	3.27e-04	94	74	4	gudmap_developingGonad_e18.5_testes_500_k3
CoexpressionAtlas	DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#3_top-relative-expression-ranked_1000	SERBP1 ALKBH2 NSD2 BYSL DAXX KIF3A BAHCC1	3.35e-04	376	74	7	gudmap_developingKidney_e11.5_metaneph mesench_1000_k3
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_500	PRSS35 TRANK1 ZMYM3	3.66e-04	40	74	3	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k2_500
CoexpressionAtlas	dev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_500	PRSS35 TRANK1 STC2 ZMYM3	3.69e-04	97	74	4	gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k1_500
CoexpressionAtlas	facebase_RNAseq_e9.5_MandArch_2500_K3	COL23A1 SCAF1 NSD2 OGFR ESRRA TMEM132A EIF4G1 BYSL MAP3K11 BUD13 HMGA1 LYAR BAHCC1	3.73e-04	1259	74	13	facebase_RNAseq_e9.5_MandArch_2500_K3
CoexpressionAtlas	gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K0	SCAF1 SPRED2 TRAF3IP1 STC2 TMEM132A MAP3K11 HMGA1 KDM6B SNRNP70 TNNI3 RSPO1 BAHCC1 SORCS1	4.21e-04	1275	74	13	gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K0
CoexpressionAtlas	FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#3	STC2 CECR2 ROBO3 LYAR RAX	4.37e-04	182	74	5	Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K3
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000	PRSS35 COL23A1 STC2 ESR1 EIF4G1 ANKRD11 KDM6B RSPO1 KIF3A AHNAK2	4.37e-04	799	74	10	gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_1000	PRSS35 TRANK1 STC2 ZMYM3	4.80e-04	104	74	4	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_1000
CoexpressionAtlas	DevelopingKidney_e11.5_ureteric bud_emap-3844_top-relative-expression-ranked_1000	SERBP1 TRAF3IP1 STC2 ALKBH2 NSD2 TMEM132A ING5 BYSL KDM3B SORCS1	5.01e-04	813	74	10	gudmap_developingKidney_e11.5_ureteric bud_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_1000	PRSS35 TRANK1 STC2 CCDC171 ZMYM3	5.45e-04	191	74	5	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k4_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	SERBP1 TRAF3IP1 HNRNPUL2 CECR2 APC2 ROBO3 LYAR CCDC171 RSPO1 SAP30 KIF3A	6.00e-04	989	74	11	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_500	COL23A1 SPRED2 KIF26B EIF4G1 KDM6B HDLBP SORCS1	6.13e-04	416	74	7	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000	PRSS35 STC2 CECR2 APC2 ANKRD11 RBM6 HMGA1 ROBO3 LYAR CCDC171 RAX	6.26e-04	994	74	11	Facebase_RNAseq_e8.5_Floor Plate_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#2	PRSS35 STC2 CECR2 ROBO3 LYAR RAX	6.48e-04	302	74	6	Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K2
CoexpressionAtlas	gudmap_RNAseq_e11.5_Ureteric_tips_2500_K1	SCAF1 STC2 KIF26B CECR2 TMEM132A HMGA1 KDM6B SNRNP70 RSPO1 BAHCC1 SORCS1	6.58e-04	1000	74	11	gudmap_RNAseq_e11.5_Ureteric_tips_2500_K1
CoexpressionAtlas	dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#2_top-relative-expression-ranked_200	TRANK1 STC2 ZMYM3	6.67e-04	49	74	3	gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k2_200
CoexpressionAtlas	facebase_RNAseq_e8.5_ParaxMesoderm_2500_K2	USP36 COL23A1 SERBP1 STC2 CECR2 EIF4G1 BYSL MAP3K11 HMGA1 LYAR RSPO1 BAHCC1	7.09e-04	1175	74	12	facebase_RNAseq_e8.5_ParaxMesoderm_2500_K2
CoexpressionAtlas	DevelopingGonad_P2_testes_emap-30171_k-means-cluster#2_top-relative-expression-ranked_500	PRSS35 COL23A1 TRANK1 TNNI3	7.48e-04	117	74	4	gudmap_developingGonad_P2_testes_500_k2
CoexpressionAtlas	facebase_RNAseq_e9.5_MaxArch_2500	COL23A1 NKD2 CCM2L ALKBH2 NSD2 CECR2 TMEM132A EIF4G1 BYSL MAP3K11 HMGA1 LYAR BAHCC1	8.33e-04	1371	74	13	facebase_RNAseq_e9.5_MaxArch_2500
Disease	body height at birth	C20orf203 ESR1 HMGA1 ADCY5	2.49e-06	40	70	4	EFO_0006784
Disease	sexual dimorphism measurement	USP36 SART1 TRANK1 ESR1 AVIL ANKRD11 RBM6 MAP3K11 BUD13 HMGA1 AGAP2 HDLBP	1.04e-05	1106	70	12	EFO_0021796
Disease	Wolf-Hirschhorn Syndrome	NSD2 NELFA	1.98e-04	9	70	2	C1956097
Disease	Malignant neoplasm of breast	STC2 NSD2 ESR1 G3BP2 ESRRA APC2 PDCD4 AGAP2 HDLBP SORCS1	2.14e-04	1074	70	10	C0006142
Disease	Metabolic Bone Disorder	ESR1 ANKRD11	4.96e-04	14	70	2	C0005944
Disease	Osteopenia	ESR1 ANKRD11	5.71e-04	15	70	2	C0029453
Disease	BMI-adjusted fasting blood glucose measurement	C2CD4B ADCY5	1.36e-03	23	70	2	EFO_0008036
Disease	pulse pressure measurement	USP36 COL23A1 TRANK1 ESR1 C11orf96 ANKRD11 ROBO3 KDM6B SNRNP70 ADCY5	1.59e-03	1392	70	10	EFO_0005763
Disease	antiphospholipid antibody measurement	COL23A1 CACNA1E	1.61e-03	25	70	2	EFO_0005200
Disease	Seizures	CACNA1E APC2 KDM3B CHAT	1.82e-03	218	70	4	C0036572
Disease	Diabetes Mellitus, Non-Insulin-Dependent	C2CD4B C2CD4A HMGA1 ADCY5	1.91e-03	221	70	4	C0011860
Disease	suntan	C20orf203 KIF3B ANKRD11	1.91e-03	103	70	3	EFO_0004279
Disease	proteinuria (implicated_via_orthology)	C6 SORCS1	2.31e-03	30	70	2	DOID:576 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
GGDKESTRKRPRREA	ALKBH2	31	Q6NS38
VEEKEKGTARAGRRQ	CEP295NL	266	Q96MC4
DAGVDRGSESGRKRR	BUD13	21	Q9BRD0
ERVEAEKGGRRRAGG	BAHCC1	2221	Q9P281
EKGGRRRAGGEFLVK	BAHCC1	2226	Q9P281
AKDIRDRERGGRAKI	AVIL	191	O75366
KLERGDGGKEVRERA	ANKRD11	41	Q6UB99
HRSGGRERGRSKERK	CACNA1E	2076	Q15878
ARKEAGLGRRAAEER	CCDC171	91	Q6TFL3
GREGGRASTRDRKML	AGAP2	331	Q99490
EEGGLRGEKRKRDAE	ANP32E	246	Q9BTT0
VEVGLEERRGKGRAA	ADCY5	156	O95622
GGAPEKRRVGTAERR	CCM2L	181	Q9NUG4
EKREKRRSRAGRSGG	CECR2	556	Q9BXF3
SEEGERKKRRARLQG	DAXX	386	Q9UER7
RGDGFDSRGKREFDR	SERBP1	181	Q8NC51
RLLKAREGTRRGTEG	PHLDB3	471	Q6NSJ2
RRVLAGEKGEVKGRA	TRAF3IP1	126	Q8TDR0
GAGREAKRRRKTLDA	NELFA	266	Q9H3P2
DVERLQRRRGGASKE	KIF26B	1996	Q2KJY2
KDSVGRRPREGRAKA	KDM6B	991	O15054
EVGGLRLSKVGRRDR	C20orf203	106	Q8NBC4
RLSKVGRRDREVGRG	C20orf203	111	Q8NBC4
VKARDEGRGRDRGRL	C2CD4B	336	A6NLJ0
SGRRDRGRSEDKKPL	LINC02901	116	Q4VX62
RGEKGDRSERGEKGE	COL23A1	486	Q86Y22
GRKRFVSEGDGGRLK	PDCD4	451	Q53EL6
KHKRQRDDGEGRGEV	ESR1	266	P03372
RRRRAKGEGKRQSED	NSD2	1226	O96028
AGSDGERRGVKRQRD	HNRNPUL2	191	Q1KMD3
RESIEGKDGRRRKSA	KDM3B	276	Q7LBC6
GEVGEDGEKRKKRRG	KIF3A	396	Q9Y496
SGRKGAEEAERRARD	NKD2	31	Q969F2
RKGRQAEGEMGSARR	APC2	1736	O95996
RGGKRCEGEKRQEED	C6	596	P13671
EKKTRAARERETRGG	G3BP2	406	Q9UN86
LSRERGEKAGDRGDR	EIF4G1	1146	Q04637
EKRGSRGRGRRTSEE	ING5	136	Q8WYH8
EEEARVGAGKRKRRH	LYAR	261	Q9NX58
RRLRGVKDGGRRDSA	DDX17	586	Q92841
KETEGARGSERQRER	C4orf54	846	D6RIA3
KEGVRLDRVRGGRQK	ESRRA	146	P11474
VKARDEGRGRERGRL	C2CD4A	341	Q8NCU7
GNAVRAGVREKRRGR	BYSL	26	Q13895
AGVREKRRGRGTGEA	BYSL	31	Q13895
GTFKRSKLRARDGGE	MAP3K11	476	Q16584
QEKDGTEKRGRGRPR	HMGA1	16	P17096
RKRRKVDEGAGDSAA	OGFR	456	Q9NZT2
RERERKEELRGGGGD	SNRNP70	301	P08621
REHKRGERGSERGRD	SNRNP70	376	P08621
KEKREKERRRHGLGG	RSBN1L	161	Q6PCB5
ERREREGKFKGRGND	RBM6	1001	P78332
TKVAEKGEAVRGGRR	VCY	36	O14598
GRGKGRGRIRSEDEE	TDRD3	246	Q9H7E2
GVRGKFERAEEEARK	TMEM132A	806	Q24JP5
LARKEAGGRRKRVEF	TMEM132A	951	Q24JP5
SVRNRRKRKGSDDDG	SAP30	121	O75446
LKRRGRGRKEGEEDQ	NBPF11	826	Q86T75
ESKEAGAGSRRRKGQ	RSPO1	231	Q2MKA7
GARGAKERDRRLGAR	RAX	56	Q9Y2V3
RRSFRDRGGAGKLEV	AHNAK2	5201	Q8IVF2
RGTGERVKREDFEAR	CFAP299	51	Q6V702
KWKREEGGGTRGRRE	CHAT	16	P28329
ERRGDVRRKGAGRAR	C11orf96	181	Q7Z7L8
RGGETKARRAREEGK	nan	96	Q6ZSR3
RRKRREKRREGGGSG	KIF3B	376	O15066
ERGGKSSQKDRRRSG	SCAF1	741	Q9H7N4
KGSRRKALDGGDRDR	SCAF1	766	Q9H7N4
SRETGRGAKGERGSK	STC2	251	O76061
REGTREHLRERAKGG	PRSS35	216	Q8N3Z0
RRRKKSGRGQRIAEG	PRSS35	231	Q8N3Z0
RLKEEEGRITIRGGK	ROBO3	206	Q96MS0
QPSRGKSRRRKEDGE	SPRED2	291	Q7Z698
ERRKRSRERGGERGS	SART1	51	O43290
EERRGEKGRALSTRC	TNNI3	66	P19429
KMNRGEGSRDRGLVR	YLPM1	1071	P49750
LRNGRRAGVKRSEGR	ZNF252P-AS1	151	Q0IIN9
GGGKIRKVRDSTGAR	HDLBP	746	Q00341
LESEKDERGRGRGSR	TRANK1	2321	O15050
DERGRGRGSRIKGIE	TRANK1	2326	O15050
GRRRRSGADQEKAER	SORCS1	106	Q8WY21
KRGAGGHGRTRRKDA	THAP4	91	Q8WY91
GRDTGPGKRKREDEA	ZMYM3	1266	Q14202
SSRKRRRKGAEGLGE	USP36	911	Q9P275