Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

DAB2IP SIPA1L3 OBSCN PLEKHG1 RASGRF2 DOK7 RTN4 PLEKHG4B ARFGEF3 ARHGAP6 PLEKHG3 ARHGEF1 ROBO1 CDH2

1.63e-0633318214GO:0051056
GeneOntologyBiologicalProcessneuron development

DAB2IP BOC MAP1A CUL7 PCDH12 SLC30A1 CSMD3 CDKL5 GORASP1 UCN HERC1 GOLGA2 DCDC2 RTN4 SIN3A LRRC4C RUNX1 CREBBP MICALL1 PLEKHG4B THBS4 CELSR3 STAU2 ROBO1 SCRIB LTK EN2 GOLGA8A CDH2

3.35e-05146318229GO:0048666
GeneOntologyBiologicalProcesscell projection morphogenesis

DAB2IP BOC NES MAP1A CUL7 SLC30A1 CDKL5 GORASP1 GOLGA2 DCDC2 RTN4 SIN3A LRRC4C PLEKHG4B THBS4 CELSR3 STAU2 ROBO1 GOLGA8A CDH2

4.38e-0582618220GO:0048858
GeneOntologyBiologicalProcessregulation of dendrite development

DAB2IP CUL7 SLC30A1 CSMD3 CDKL5 GORASP1 STAU2 ROBO1

5.71e-051501828GO:0050773
GeneOntologyBiologicalProcessneuron projection development

DAB2IP BOC MAP1A CUL7 SLC30A1 CSMD3 CDKL5 GORASP1 UCN HERC1 GOLGA2 DCDC2 RTN4 SIN3A LRRC4C CREBBP MICALL1 PLEKHG4B THBS4 CELSR3 STAU2 ROBO1 SCRIB LTK GOLGA8A CDH2

6.40e-05128518226GO:0031175
GeneOntologyBiologicalProcessneuron projection morphogenesis

DAB2IP BOC MAP1A CUL7 SLC30A1 CDKL5 GORASP1 GOLGA2 DCDC2 RTN4 SIN3A LRRC4C PLEKHG4B THBS4 CELSR3 STAU2 ROBO1 GOLGA8A CDH2

9.15e-0580218219GO:0048812
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

BOC MAP1A CUL7 SLC30A1 CDKL5 GORASP1 GOLGA2 DCDC2 RTN4 SIN3A LRRC4C PLEKHG4B CELSR3 STAU2 ROBO1 SCRIB GOLGA8A CDH2

1.16e-0474818218GO:0048667
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

DAB2IP BOC MAP1A CUL7 SLC30A1 CDKL5 GORASP1 GOLGA2 DCDC2 RTN4 SIN3A LRRC4C PLEKHG4B THBS4 CELSR3 STAU2 ROBO1 GOLGA8A CDH2

1.20e-0481918219GO:0120039
GeneOntologyCellularComponenttranscription repressor complex

ZFPM1 MEN1 BIN1 SIN3A RLIM SPEN

1.16e-04871836GO:0017053
GeneOntologyCellularComponentpostsynaptic density

SYN3 MAP1A RUSC1 SLC30A1 CDKL5 MPP2 RTN4 LRRC4C INSYN2A CELSR3 SCRIB IGSF21 CDH2

1.79e-0445118313GO:0014069
GeneOntologyCellularComponentneuron to neuron synapse

SYN3 MAP1A RUSC1 SLC30A1 CDKL5 MPP2 RTN4 LRRC4C INSYN2A CELSR3 SUMO2 SCRIB IGSF21 CDH2

2.17e-0452318314GO:0098984
GeneOntologyCellularComponentasymmetric synapse

SYN3 MAP1A RUSC1 SLC30A1 CDKL5 MPP2 RTN4 LRRC4C INSYN2A CELSR3 SCRIB IGSF21 CDH2

3.08e-0447718313GO:0032279
GeneOntologyCellularComponentpostsynaptic specialization membrane

SLC30A1 MPP2 RTN4 LRRC4C CELSR3 SCRIB IGSF21 CDH2

4.05e-042011838GO:0099634
GeneOntologyCellularComponentpostsynaptic density membrane

SLC30A1 MPP2 RTN4 LRRC4C CELSR3 SCRIB IGSF21

4.75e-041571837GO:0098839
GeneOntologyCellularComponentpostsynaptic specialization

SYN3 MAP1A RUSC1 SLC30A1 CDKL5 MPP2 RTN4 LRRC4C INSYN2A CELSR3 SCRIB IGSF21 CDH2

5.08e-0450318313GO:0099572
HumanPhenoBroad forehead

ZBTB20 CUL7 CDKL5 RECQL4 RBM8A SIN3A MED13L ZFPM2 RLIM ROBO1 MESP2 CDH2

2.28e-062055812HP:0000337
HumanPhenoAbnormal penis morphology

AXL CUL7 SRCAP NSUN2 RYR1 MEN1 CDKL5 ABCD1 HERC1 MAMLD1 SIN3A HUWE1 CREBBP ZFPM2 USF3 GUCY1A1 RLIM ROBO1 MESP2 SPEN CDH2

1.72e-057125821HP:0000036
HumanPhenoKyphosis

ZBTB20 CUL7 SRCAP RYR1 SCAF4 CDKL5 SYNE2 RECQL4 HERC1 BIN1 COL12A1 DOK7 ZNF407 SIN3A USF3 MESP2 SPEN

3.11e-055105817HP:0002808
DomainGAGE

GAGE4 GAGE5 GAGE6 PAGE5 GAGE12I GAGE2E GAGE12J GAGE12F GAGE13 GAGE1

1.46e-142418810PF05831
DomainGAGE_fam

GAGE4 GAGE5 GAGE6 PAGE5 GAGE12I GAGE2E GAGE12J GAGE12F GAGE13 GAGE1

2.41e-142518810IPR008625
DomainGAGE

GAGE4 GAGE6 PAGE5 GAGE12F GAGE1

1.02e-06191885IPR031320
DomainGAGE

GAGE4 GAGE6 PAGE5 GAGE12F GAGE1

1.02e-06191885SM01379
DomainDH_1

OBSCN PLEKHG1 RASGRF2 PLEKHG4B PLEKHG3 ARHGEF1

4.05e-05631886PS00741
DomainRhoGEF

OBSCN PLEKHG1 RASGRF2 PLEKHG4B PLEKHG3 ARHGEF1

6.26e-05681886SM00325
DomainRhoGEF

OBSCN PLEKHG1 RASGRF2 PLEKHG4B PLEKHG3 ARHGEF1

7.38e-05701886PF00621
DomainDH_2

OBSCN PLEKHG1 RASGRF2 PLEKHG4B PLEKHG3 ARHGEF1

7.38e-05701886PS50010
Domain-

OBSCN PLEKHG1 RASGRF2 PLEKHG4B PLEKHG3 ARHGEF1

7.99e-057118861.20.900.10
DomainDH-domain

OBSCN PLEKHG1 RASGRF2 PLEKHG4B PLEKHG3 ARHGEF1

7.99e-05711886IPR000219
DomainZF_CCHC_FOG

ZFPM1 ZFPM2

1.01e-0421882PS51810
PathwayBIOCARTA_RHO_PATHWAY

GSN ARHGAP6 ARHGEF1 TLN1

2.40e-05201234MM1476
PathwayBIOCARTA_RHO_PATHWAY

GSN ARHGAP6 ARHGEF1 TLN1

2.94e-05211234M1001
PathwayREACTOME_RHO_GTPASE_CYCLE

EPSTI1 OBSCN PLEKHG1 GOLGA2 ANKFY1 RASGRF2 ACBD5 ARHGAP6 PLEKHG3 ARHGEF1 SCRIB SPEN GOLGA8A

1.19e-0443912313MM15595
Pubmed

An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members.

GAGE4 GAGE5 GAGE6 GAGE7 GAGE12I GAGE2E GAGE12J GAGE12F GAGE13 GAGE1

4.51e-18201961018179644
Pubmed

Isolation and characterization of PAGE-1 and GAGE-7. New genes expressed in the LNCaP prostate cancer progression model that share homology with melanoma-associated antigens.

GAGE4 GAGE5 GAGE6 GAGE7 GAGE12I GAGE2E GAGE1

1.92e-141019679651357
Pubmed

Characterization of the GAGE genes that are expressed in various human cancers and in normal testis.

GAGE4 GAGE5 GAGE6 GAGE7 GAGE12I GAGE2E GAGE1

5.25e-1411196710397259
Pubmed

A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma.

GAGE4 GAGE5 GAGE6 GAGE12I GAGE1

6.68e-10919657544395
Pubmed

A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.

GAGE5 GAGE6 GAGE7 GAGE12I GAGE2E GAGE12J GAGE12F GAGE13 GAGE12G GAGE1

1.60e-091191961028625976
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DAB2IP TSPOAP1 CSMD3 PLEKHG1 ANKFY1 ZSWIM5 LRRC4C MED13L ARFGEF3 RPAP1 TLN1 SCRIB SPEN CEP170B AQR

1.28e-084071961512693553
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

DAB2IP SIPA1L3 SYNE2 PLCB1 SMG6 DCDC2 ANKFY1 MED13L TLN1 PCNX1 SCRIB

7.05e-082251961112168954
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

BOC FAM114A1 OBSCN PCDH12 SUCLG2 RYR1 SYNE2 BIN1 ANKFY1 COL12A1 RASGRF2 ZNF407 TLN1 SNAPC3 TGS1

1.73e-074971961523414517
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

DAB2IP SIPA1L3 OBSCN ZFPM1 SRCAP RYR1 PLEKHG1 EHBP1L1 ABCD1 HERC1 SMG6 AOC2 HUWE1 MED13L MICALL1 CELSR3 RPAP1 TLN1 PCNX1 LTK SPEN CEP170B

3.35e-0711051962235748872
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

DAB2IP NES NHSL2 SIPA1L3 ITIH4 SYNE2 PLCB1 GOLGA2 SMG6 MPP2 BIN1 DNAJC13 ANKFY1 HUWE1 GSN TXLNA SCRIB GOLGA8A CDH2 CEP170B

6.20e-079631962028671696
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

OBSCN SSPOP CTTNBP2NL RYR1 RECQL4 DNAH2 PIWIL2 AMER3 HUWE1 ATXN1L THBS4 GIMAP8 RPAP1 GTF3C1 TLN1 SCRIB ZBTB11

1.08e-067361961729676528
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

SPATA31E1 MAP1A TSPOAP1 RAD54L2 ZNF469 TMEM139 SIN3A PLEKHG4B ARHGAP6 USF3 TLN1 MDC1 SPEN

1.15e-064301961335044719
Pubmed

SLMAP3 is essential for neurulation through mechanisms involving cytoskeletal elements, ABP, and PCP.

NES GOLGA2 SCRIB GOLGA8A CDH2

1.53e-0635196539366759
Pubmed

Association of coagulation factor XIII-A with Golgi proteins within monocyte-macrophages: implications for subcellular trafficking and secretion.

F13A1 GOLGA2 TGOLN2

1.75e-065196320086247
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

CAAP1 ZFPM1 NSUN2 CTTNBP2NL SCAF4 RBM8A BIN1 DNAJC13 SIN3A HUWE1 RUNX1 MICALL1 RPAP1 GTF3C1 MDC1 SCRIB SPEN

2.14e-067741961715302935
Pubmed

N-cadherin sustains motility and polarity of future cortical interneurons during tangential migration.

NES GOLGA2 GOLGA8A CDH2

2.81e-0618196424227724
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

MAP1A SIPA1L3 CTTNBP2NL SNX29 ARFGEF3 STAU2 ROBO1 SCRIB CEP170B

3.19e-06209196936779422
Pubmed

Pilt is a coiled-coil domain-containing protein that localizes at the trans-Golgi complex and regulates its structure.

GORASP1 GOLGA2 TGOLN2 GOLGA8A

3.55e-0619196422841714
Pubmed

Differential expression of individual gamma-protocadherins during mouse brain development.

PCDHGA4 PCDHGB4 CDH2

6.07e-067196315964765
Pubmed

A unique SUMO-2-interacting motif within LANA is essential for KSHV latency.

SIN3A CREBBP SUMO2

6.07e-067196324278015
Pubmed

Essential role of cyclin-G-associated kinase (Auxilin-2) in developing and mature mice.

NES GOLGA2 TGOLN2 GOLGA8A

9.52e-0624196418434600
Pubmed

A Golgi Lipid Signaling Pathway Controls Apical Golgi Distribution and Cell Polarity during Neurogenesis.

NES GORASP1 GOLGA2 GOLGA8A

1.13e-0525196429587143
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ZBTB20 SIPA1L3 OBSCN SSPOP EXD3 TECPR2 SMG6 DNAJC13 MAN2B2 HUWE1 CREBBP PLBD2 SNX29 PLEKHG4B ARFGEF3 ARHGAP6 USF3 GTF3C1 GUCY1A1 PLEKHG3 TTLL11 SYTL1 CEP170B

1.25e-0514891962328611215
Pubmed

Human transcription factor protein interaction networks.

TET2 RAD54L2 CUL7 SRCAP TRIM24 NSUN2 SCAF4 SYNE2 HERC1 HSPA4 SIN3A ATXN1L CREBBP ZFPM2 GTF3C1 DPF3 MDC1 STAU2 RLIM SUMO2 SPEN RAI2

2.06e-0514291962235140242
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

RAD54L2 NSUN2 GORASP1 RECQL4 GOLGA2 RTN4 SIN3A TXLNA RPAP1 GTF3C1 ARHGEF1 SCRIB ZBTB11 AQR

2.15e-056501961438777146
Pubmed

The DNA sequence of the human X chromosome.

GAGE7 PAGE5 GAGE12I GAGE2E CDKL5 ABCD1 TCEAL8 VGLL1 GAGE12J HUWE1 GAGE13

2.20e-054071961115772651
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

NES CUL7 SRCAP NSUN2 SCAF4 SYNE2 RBM8A HSPA4 HUWE1 GSN RPAP1 GTF3C1 PLEKHG3 TLN1 MDC1 SCRIB SPEN AQR

2.22e-0510241961824711643
Pubmed

Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice.

NES GOLGA2 GOLGA8A CDH2

2.73e-0531196417765678
Pubmed

CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder.

HSPA4 CREBBP CDH2

2.81e-0511196336385105
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

DAB2IP SYN3 MAP1A XKR4 PLCB1 MPP2 BIN1 RTN4 MB21D2 CEP170B

3.05e-053471961017114649
Pubmed

Single-cell RNA-Seq reveals a highly coordinated transcriptional program in mouse germ cells during primordial follicle formation.

SYNE2 SDC1 GOLGA2 DPF3 GOLGA8A

3.14e-0564196534174788
Pubmed

The Golgi protein GM130 regulates centrosome morphology and function.

GORASP1 GOLGA2

3.16e-052196218045989
Pubmed

Sp1/Sp3 and the myeloid zinc finger gene MZF1 regulate the human N-cadherin promoter in osteoblasts.

MZF1 CDH2

3.16e-052196215541732
Pubmed

Essential role of obscurin kinase-1 in cardiomyocyte coupling via N-cadherin phosphorylation.

OBSCN CDH2

3.16e-052196238127465
Pubmed

Inheriting a structural scaffold for Golgi biosynthesis.

GORASP1 GOLGA2

3.16e-052196212111718
Pubmed

Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers.

ZFPM1 ZFPM2

3.16e-052196210329627
Pubmed

GM130 and GRASP65-dependent lateral cisternal fusion allows uniform Golgi-enzyme distribution.

GORASP1 GOLGA2

3.16e-052196216489344
Pubmed

Structural basis for the interaction between the Golgi reassembly-stacking protein GRASP65 and the Golgi matrix protein GM130.

GORASP1 GOLGA2

3.16e-052196226363069
Pubmed

Mutations in SRCAP, encoding SNF2-related CREBBP activator protein, cause Floating-Harbor syndrome.

SRCAP CREBBP

3.16e-052196222265015
Pubmed

TET2 Negatively Regulates Nestin Expression in Human Melanoma.

TET2 NES

3.16e-052196227102770
Pubmed

GAGE7B promotes tumor metastasis and growth via activating the p38δ/pMAPKAPK2/pHSP27 pathway in gastric cancer.

GAGE12I GAGE12F

3.16e-052196230871606
Pubmed

Myeloid zinc finger 1 induces migration, invasion, and in vivo metastasis through Axl gene expression in solid cancer.

AXL MZF1

3.16e-052196220145042
Pubmed

GRASP65, a protein involved in the stacking of Golgi cisternae.

GORASP1 GOLGA2

3.16e-05219629346242
Pubmed

Activation of the repulsive receptor Roundabout inhibits N-cadherin-mediated cell adhesion.

ROBO1 CDH2

3.16e-052196212360290
Pubmed

Acquired TET2 mutation in one patient with familial platelet disorder with predisposition to AML led to the development of pre-leukaemic clone resulting in T2-ALL and AML-M0.

TET2 RUNX1

3.16e-052196227997762
Pubmed

The GM130 and GRASP65 Golgi proteins cycle through and define a subdomain of the intermediate compartment.

GORASP1 GOLGA2

3.16e-052196211781572
Pubmed

Excess LINC complexes impair brain morphogenesis in a mouse model of recessive TOR1A disease.

NES SYNE2 CDH2

3.74e-0512196329868845
Pubmed

EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells.

EHBP1L1 BIN1 MICALL1

4.84e-0513196326833786
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TET2 CTTNBP2NL TECPR2 PLCB1 SMG6 RTN4 KIAA1614 MICALL1 CELSR3 MDC1 PCNX1 IGSF1

5.15e-055291961214621295
Pubmed

Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains.

GOLGA2 EN2 GOLGA8A CDH2

5.58e-0537196425742799
Pubmed

E protein silencing by the leukemogenic AML1-ETO fusion protein.

SIN3A RUNX1 CREBBP

6.13e-0514196315333839
Pubmed

High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.

TET2 TCEAL8 SMG6 PCDHGA4 MAMLD1 USP43 CREBBP TXLNA CDH2

6.69e-05307196937499664
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

MAP1A SIPA1L3 MRPL19 ITIH4 RYR1 RBM8A DNAJC13 RTN4 MED13L GTF3C1 PLEKHG3 STAU2 SLC45A2 SUMO2

7.73e-057321961434732716
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

NES NSUN2 CTTNBP2NL RTN4 SIN3A HUWE1 RPAP1 SCRIB

8.34e-05246196815345747
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

NES SRCAP SUCLG2 NSUN2 RECQL4 RBM8A HSPA4 SDC1 DNAJC13 ANKFY1 HUWE1 RUNX1 CREBBP GTF3C1 PLEKHG3 ARHGEF1 TLN1 MDC1 SCRIB AQR

8.71e-0513531962029467282
Pubmed

Rbx2 regulates neuronal migration through different cullin 5-RING ligase adaptors.

NES GOLGA2 GOLGA8A CDH2

9.26e-0542196424210661
Pubmed

SLC24A5 encodes a trans-Golgi network protein with potassium-dependent sodium-calcium exchange activity that regulates human epidermal melanogenesis.

GOLGA2 TGOLN2 GOLGA8A

9.35e-0516196318166528
Pubmed

A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations.

CREBBP CDH2

9.44e-053196213678586
Pubmed

The niche factor syndecan-1 regulates the maintenance and proliferation of neural progenitor cells during mammalian cortical development.

NES SDC1

9.44e-053196222936997
Pubmed

AML1-FOG2 fusion protein in myelodysplasia.

RUNX1 ZFPM2

9.44e-053196215705784
Pubmed

The corepressor mSin3A regulates phosphorylation-induced activation, intranuclear location, and stability of AML1.

SIN3A RUNX1

9.44e-053196214729951
Pubmed

GRASP55, a second mammalian GRASP protein involved in the stacking of Golgi cisternae in a cell-free system.

GORASP1 GOLGA2

9.44e-053196210487747
Pubmed

Inhibition of cotranslational translocation by apratoxin S4: Effects on oncogenic receptor tyrosine kinases and the fate of transmembrane proteins produced in the cytoplasm.

HSPA4 HUWE1

9.44e-053196234909679
Pubmed

Lack of association between genetic polymorphisms in ROBO1, MRPL19/C2ORF3 and THEM2 with developmental dyslexia.

MRPL19 ROBO1

9.44e-053196223954868
Pubmed

Markers of malignant prostate cancer cells: Golgi localization of α-mannosidase 1A at GM130-GRASP65 site and appearance of high mannose N-glycans on cell surface.

GORASP1 GOLGA2

9.44e-053196232331836
Pubmed

TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells.

TET2 CD1D

9.44e-053196227869820
Pubmed

Rab1 interaction with a GM130 effector complex regulates COPII vesicle cis--Golgi tethering.

GORASP1 GOLGA2

9.44e-053196211285137
Pubmed

Disruption of the menin-MLL interaction triggers menin protein degradation via ubiquitin-proteasome pathway.

MEN1 HSPA4

9.44e-053196231497350
Pubmed

Mapping the interaction between GRASP65 and GM130, components of a protein complex involved in the stacking of Golgi cisternae.

GORASP1 GOLGA2

9.44e-05319629628863
Pubmed

Dysregulation of Transcription Factor Activity During Formation of Cancer-Associated Fibroblasts.

RUNX1 FER1L4

9.44e-053196233228208
Pubmed

Identification of a novel SNF2/SWI2 protein family member, SRCAP, which interacts with CREB-binding protein.

SRCAP CREBBP

9.44e-053196210347196
Pubmed

t(15;21) translocations leading to the concurrent downregulation of RUNX1 and its transcription factor partner genes SIN3A and TCF12 in myeloid disorders.

SIN3A RUNX1

9.44e-053196226671595
Pubmed

Beyond genes: A systematic review of environmental risk factors in specific reading disorder.

MRPL19 DCDC2

9.44e-053196229566979
Pubmed

Arhgef1 is expressed in cortical neural progenitor cells and regulates neurite outgrowth of newly differentiated neurons.

NES ARHGEF1

9.44e-053196227923664
Pubmed

NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation.

NSUN2 SUMO2

9.44e-053196234504059
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

DAB2IP SIPA1L3 SLC30A1 CDKL5 EHBP1L1 GOLGA2 RTN4 USP43 MICALL1 MB21D2 TLN1 SCRIB

9.60e-055651961225468996
Pubmed

Brain-specific Wt1 deletion leads to depressive-like behaviors in mice via the recruitment of Tet2 to modulate Epo expression.

TET2 NES ALDH1L1

1.13e-0417196332393787
Pubmed

The Protein Tyrosine Phosphatase MEG2 Regulates the Transport and Signal Transduction of Tropomyosin Receptor Kinase A.

GOLGA2 TGOLN2 GOLGA8A

1.13e-0417196327655914
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

CUL7 RYR1 CDKL5 BIN1 RTN4 TGOLN2 CELSR3 SNAPC3 SPEN

1.13e-04329196917474147
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

RAD54L2 SRCAP NSUN2 SIN3A HUWE1 GTF3C1 TLN1 MDC1 SUMO2

1.21e-04332196932786267
Pubmed

Altered GLUT4 trafficking in adipocytes in the absence of the GTPase Arfrp1.

GOLGA2 TGOLN2 GOLGA8A

1.35e-0418196320230794
Pubmed

Midline radial glia translocation and corpus callosum formation require FGF signaling.

NES ROBO1 CDH2

1.35e-0418196316715082
Pubmed

Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2.

GOLGA2 TGOLN2 GOLGA8A

1.35e-0418196320943658
Pubmed

Protein kinase LKB1 regulates polarized dendrite formation of adult hippocampal newborn neurons.

GORASP1 GOLGA2 GOLGA8A

1.35e-0418196324367100
Pubmed

Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators.

TET2 ZFPM1 RUNX1

1.35e-0418196320887958
Pubmed

Characterization of the piRNA complex from rat testes.

RAD54L2 GOLGA2 ANKFY1 TGOLN2 SCRIB GOLGA8A

1.49e-04140196616778019
Pubmed

Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation.

NES EN2 CDH2

1.60e-0419196318697938
Pubmed

CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development.

GOLGA2 RUNX1 GOLGA8A

1.60e-0419196335705037
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

NES SYN3 MAP1A SIPA1L3 ALDH1L1 CDKL5 HSPA4 MTUS2 MPP2 BIN1 DNAJC13 RTN4 GSN THBS4 ARHGEF1 CRACDL TLN1 SCRIB CDH2 CEP170B

1.84e-0414311962037142655
Pubmed

Interaction network of human early embryonic transcription factors.

TET2 RAD54L2 TRIM24 ATXN1L CREBBP DPF3 MDC1 SPEN CDH2

1.84e-04351196938297188
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

TET2 RAD54L2 TRIM24 NSUN2 SCAF4 HSPA4 SIN3A MED13L RUNX1 ATXN1L CREBBP GSN TXLNA GTF3C1 TLN1 SUMO2 SPEN

1.85e-0411031961734189442
Pubmed

Maximizing the ovarian reserve in mice by evading LINE-1 genotoxicity.

GOLGA2 PIWIL2 GOLGA8A

1.87e-0420196331949138
Pubmed

Isoform-specific localization of Nogo protein in the optic pathway of mouse embryos.

NES RTN4

1.88e-044196226718118
Pubmed

Friend of GATA and GATA-6 modulate the transcriptional up-regulation of hepcidin in hepatocytes during inflammation.

ZFPM1 ZFPM2

1.88e-044196224179092
Pubmed

Zscan5b Deficiency Impairs DNA Damage Response and Causes Chromosomal Aberrations during Mitosis.

ZSCAN5B ZSCAN5C

1.88e-044196231155506
Pubmed

Adenovirus DNA binding protein interacts with the SNF2-related CBP activator protein (SrCap) and inhibits SrCap-mediated transcription.

SRCAP CREBBP

1.88e-044196211581372
Pubmed

Paradoxical association of TET loss of function with genome-wide DNA hypomethylation.

TET2 CD1D

1.88e-044196231371502
Pubmed

EHD3 Protein Is Required for Tubular Recycling Endosome Stabilization, and an Asparagine-Glutamic Acid Residue Pair within Its Eps15 Homology (EH) Domain Dictates Its Selective Binding to NPF Peptides.

ANKFY1 MICALL1

1.88e-044196227189942
Pubmed

Molecular similarity between myelodysplastic form of chronic myelomonocytic leukemia and refractory anemia with ring sideroblasts.

TET2 RUNX1

1.88e-044196223065512
Pubmed

Tripartite Motif Containing 24 Acts as a Novel Coactivator of the Constitutive Active/Androstane Receptor.

TRIM24 HSPA4

1.88e-044196229101097
CytobandXp11.4-p11.2

GAGE4 GAGE5 GAGE6 GAGE7

4.80e-0961964Xp11.4-p11.2
CytobandXp11.23

GAGE12I GAGE2E GAGE12J GAGE12F GAGE13 GAGE12G GAGE1

1.87e-07951967Xp11.23
CytobandEnsembl 112 genes in cytogenetic band chrXp11

PAGE5 GAGE2E GAGE12J HUWE1 GAGE12F GAGE13 GAGE12G GAGE1

2.35e-043771968chrXp11
Cytoband3q13.2

BOC ZBTB20 USF3

3.15e-043119633q13.2
Cytoband6p21.1

CUL7 PGC TCTE1 TOMM6

3.95e-048019646p21.1
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

OBSCN PLEKHG1 RASGRF2 PLEKHG3 ARHGEF1

6.52e-05661165722
GeneFamilyFibronectin type III domain containing

BOC TSPOAP1 AXL OBSCN COL12A1 ROBO1

5.82e-041601166555
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZBTB20 ZNF200 ZFPM1 ZSCAN25 ZNF469 GLI4 ZNF407 ZFPM2 ZSCAN5B MZF1 ZSCAN5C ZNF488 ZBTB11

7.00e-047181161328
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_500

SRCAP SYNE2 HERC1 DNAJC13 ANKFY1 RUNX1 CREBBP RLIM CDH2

4.29e-071071869gudmap_developingGonad_e14.5_ epididymis_500_k2
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

ZBTB20 SYNE2 PLCB1 HERC1 SMG6 ZNF407 HUWE1 MED13L PCNX1 ZBTB11 SPEN

5.42e-1018818911ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYN3 CTTNBP2NL OGFRL1 DCDC2 MAMLD1 THBS4 MB21D2 SNAPC3

6.26e-071681898d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCellCOVID-19-Heart-EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

NES SYN3 PLEKHG1 PLCB1 ADAMTS4 RASGRF2 THBS4 GUCY1A1

1.15e-061821898e67f3234165199085c793915ebb1f9bbd845e933
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN CSMD3 SSPOP COL12A1 LRRC4C ARFGEF3 ROBO1 ZNF488

1.24e-0618418982cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN CSMD3 SSPOP COL12A1 LRRC4C ARFGEF3 ROBO1 ZNF488

1.24e-0618418982b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN CSMD3 SSPOP COL12A1 LRRC4C ARFGEF3 ROBO1 ZNF488

1.24e-061841898ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZBTB20 XKR4 SYNE2 PLCB1 DCDC2 USP43 SNX29 SLC45A2

1.46e-061881898af740fa78542438fdff627ea1f74f4eee43316be
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

NHSL2 AXL COL12A1 ADAMTS4 ZFPM2 ARHGAP6 MB21D2 GUCY1A1

1.64e-06191189878c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellLA|World / Chamber and Cluster_Paper

F13A1 PLCB1 COL12A1 RTN4 GSN ARHGAP6 ABCA6 ROBO1

1.78e-061931898d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-8|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

NES MAP1A AXL PCDH12 F13A1 ZNF469 COL12A1 THBS4

1.85e-06194189855b97095a7a17a312c616703d291738a0f806339
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-muscle|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

BOC NES RYR1 ANKRD2 BIN1 DOK7 ZNF488 SCRIB

1.92e-06195189880b973d2a23ef9b101c90e1635e68c9a3f78f65d
ToppCellCOPD-Myeloid-Macrophage|Myeloid / Disease state, Lineage and Cell class

TET2 CTTNBP2NL F13A1 MAMLD1 PLBD2 SNX29 MB21D2 IGSF21

2.23e-0619918981cf1b2d6debf9e3389f1829dcaa2857e9533a080
ToppCellCOPD-Myeloid-Macrophage|COPD / Disease state, Lineage and Cell class

TET2 CTTNBP2NL F13A1 MAMLD1 PLBD2 SNX29 MB21D2 IGSF21

2.23e-0619918984b9c53fb4f44190d2f6ad4d52b13be01ebe4955e
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Club_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TECPR2 TTLL10 SDC1 TMEM139 DOK7 FER1L4 SYTL1

6.08e-061621897aed15eef32419b8a4e2afdb9776c2bf2802e96f1
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PCDH12 F13A1 LRRC4C GSN ARHGAP6 ZSCAN5B IGSF21

6.33e-0616318974b8abbad4df040c895e3afb240759ebbc66b4d0e
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYN3 NHSL2 LCA5 RASGRF2 ZFPM2 CRACDL LTK

1.04e-05176189707abf29d681abdd6c7cc87f9eaf9377e92ce212c
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

ZBTB20 DNAJC13 ZNF407 WBP2NL HUWE1 TGOLN2 CEP170B

1.08e-05177189782fdd6185b368f54f03de389427cbe3071d21a99
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYN3 NHSL2 LCA5 RASGRF2 ZFPM2 CRACDL LTK

1.12e-0517818975d6297f34e104bacefb25c4e2338b50fe13dd19a
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC PLCB1 COL12A1 GSN THBS4 ABCA6 GUCY1A1

1.30e-0518218973dfa9187e9d2bab1d199079d29209c4648220ada
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLCB1 COL12A1 GSN ZFPM2 THBS4 ABCA6 ROBO1

1.30e-051821897fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell3'_v3-Lung-Myeloid_Dendritic-DC1|Lung / Manually curated celltypes from each tissue

PXDC1 MTUS2 PLEKHG4B ABCA6 ROBO1 IGSF21 CDH2

1.35e-051831897e4cbd39575b5a4612d9934532e3bad63286f8aa5
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

DAB2IP CDKL5 ABCD1 TMEM139 COL12A1 GOLGA8A RAI2

1.35e-0518318976821dca076318115d360ff426eb1218cfe104063
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYN3 NHSL2 ZNF469 RASGRF2 ZFPM2 CRACDL LTK

1.35e-0518318971645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYN3 NHSL2 ZNF469 RASGRF2 ZFPM2 CRACDL LTK

1.39e-05184189734e316ad8e7b8667cd8ad61397281802a252744f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NHSL2 XKR4 DCDC2 DOK7 ZFPM2 ROBO1 CDH2

1.44e-0518518978816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NHSL2 XKR4 DCDC2 DOK7 ZFPM2 ROBO1 CDH2

1.44e-05185189734fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZBTB20 XKR4 SYNE2 PLCB1 USP43 SNX29 SLC45A2

1.49e-051861897f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

SIPA1L3 PLCB1 SMG6 DCDC2 RASGRF2 ZSWIM5 ROBO1

1.49e-051861897de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

SIPA1L3 PLCB1 SMG6 DCDC2 RASGRF2 ZSWIM5 ROBO1

1.49e-0518618970b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

ZBTB20 AXL PLCB1 COL12A1 GSN ABCA6 ROBO1

1.55e-0518718974ea486991f66c29728d127171a07b81404ec0b78
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ZBTB20 ALDH1L1 PLEKHG1 PLCB1 DCDC2 RASGRF2 ZSWIM5

1.55e-051871897f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NHSL2 XKR4 DCDC2 DOK7 ZFPM2 PLEKHG3 ROBO1

1.60e-051881897b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

BOC PLCB1 COL12A1 GSN ZFPM2 ABCA6 ROBO1

1.60e-051881897fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NHSL2 XKR4 DCDC2 DOK7 ZFPM2 PLEKHG3 ROBO1

1.60e-051881897874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

OBSCN ANKRD2 PLCB1 MTUS2 ZFPM2 DPF3 CDH2

1.71e-051901897918ad5037881212008f9f69d5df5da91fd01422c
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CTTNBP2NL F13A1 RYR1 CALCR ARHGAP6 MB21D2 IGSF21

1.71e-0519018972d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCellFibroblasts-CD55+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

AXL MFSD6 BIRC7 ITIH4 MTUS2 AMTN THBS4

1.71e-051901897b4088128f5acf53f43244c9af9fe44e033f1a57a
ToppCellCOVID-19-Heart-Mito_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

NES MAP1A RYR1 ANKRD2 PLCB1 RASGRF2 GSN

1.71e-051901897ea74e0e38bcaba125b48c88331e9ba09228d3178
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

ANKFY1 WBP2NL HUWE1 TGOLN2 USPL1 SPEN RNF111

1.77e-0519118979454f642c3621370fa23640b631301346b300950
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

AXL PLCB1 COL12A1 GSN ARHGAP6 ABCA6 ROBO1

1.83e-051921897356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

AXL PLCB1 COL12A1 GSN ARHGAP6 ABCA6 ROBO1

1.90e-051931897dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AXL CTTNBP2NL RYR1 ZNF469 OGFRL1 GSN CD1D

1.96e-0519418972210f0755882d8f04edb4c109fb17c3f9149f6f7
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AXL CTTNBP2NL RYR1 ZNF469 OGFRL1 GSN CD1D

1.96e-051941897b16ed97eb6b7b7a220e943474c0d85c141b6e3a5
ToppCellCOPD-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

TET2 AXL CTTNBP2NL F13A1 MB21D2 PCNX1 IGSF21

1.96e-0519418977d682408e9a6239a4e47befc9376e760cc3d133a
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

SYN3 AXL PLCB1 GSN ZFPM2 ABCA6 ROBO1

2.03e-0519518976a02ebbeb3199447ddce64d92d8809436e040eba
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYN3 CTTNBP2NL PLEKHG1 RASGRF2 GSN GIMAP8 DPF3

2.03e-051951897d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CTTNBP2NL F13A1 MAMLD1 AMER3 CD1D MB21D2 IGSF21

2.16e-051971897e2983ae16c72371fbf0e5c123de9f4d900724e5e
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

PXDC1 CTTNBP2NL RYR1 DOK7 GSN ABCA6 PLEKHG3

2.16e-051971897a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

PXDC1 CTTNBP2NL RYR1 DOK7 GSN ABCA6 PLEKHG3

2.16e-05197189715b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AXL EHBP1L1 PLCB1 ADAMTS4 ARHGAP6 ZSCAN5B CDH2

2.24e-051981897bd42c03e384e64f61b02618cf1a5440033bb04b2
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NES PCDH12 PLEKHG1 ZFPM2 ARHGAP6 GIMAP8 LTK

2.31e-051991897dc88ce36cc066eb6c28cfd5b9b60fe07f8cc7b53
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Synpr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SSPOP PGC ADAMTS4 PLEKHG3 ZNF488 EN2

2.33e-0513418963dd4b5eddc94c1d49ab23b287ee234db3a55331b
ToppCellmild-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TET2 EPSTI1 AXL CTTNBP2NL OGFRL1 GSN CD1D

2.38e-05200189786f585bf9066b179bbcbc703bf43f15da4a07284
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)|Neuronal / cells hierarchy compared to all cells using T-Statistic

SYN3 NHSL2 ZNF469 RASGRF2 ZFPM2 CRACDL LTK

2.38e-0520018970f23e72649a274043bf23e0952a9b5707c516acf
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Macroglial-Glia_progenitor_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

EPSTI1 SUCLG2 DNAJC13 LRRC4C RUNX1 THBS4 ZNF488

2.38e-0520018976c1b7b0f3cd35d8cfee181ea83c73127dbc41ac5
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Synpr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SSPOP ADAMTS4 GSN PLEKHG3 ZNF488 EN2

2.64e-051371896b03f19b233c1c809f2cd2b4a7642eeaf254a6289
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

SYN3 CSMD3 RYR1 MTUS2 LRRC4C MALRD1

2.87e-05139189664c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSPOP CALCR LIN28B MAMLD1 ZFPM2 SLC45A2

2.99e-0514018967ca49bd7ba9381e75c10f888775df17e5d46804d
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSPOP CALCR LIN28B MAMLD1 ZFPM2 SLC45A2

2.99e-0514018961a31bc33d5723b9bc528cc0047ca5f4c80531c7a
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Cerebellum / BrainAtlas - Mouse McCarroll V32

KIF24 RECQL4 USP43 SLC45A2 SUMO2

3.10e-05851895bb9555652e93620d5aeeb71e915b3978a437407d
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

KIF24 RECQL4 USP43 SLC45A2 SUMO2

3.10e-05851895f7935c3206310adafdecb75149c3b06c38e7780c
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

KIF24 RECQL4 USP43 SLC45A2 SUMO2

3.10e-0585189543f6911b032718d8ba75fb7bba5f9b536a4b3260
ToppCellPND07-28-samps-Mesenchymal-Pericyte|PND07-28-samps / Age Group, Lineage, Cell class and subclass

EID2 USP43 LRRC4C ARHGAP6 CDH2 RAI2

4.40e-0515018965b111ec11a642d63fafa7e1422e36f81a2776531
ToppCellPND07-28-samps-Mesenchymal-Pericyte-pericyte_F|PND07-28-samps / Age Group, Lineage, Cell class and subclass

EID2 USP43 LRRC4C ARHGAP6 CDH2 RAI2

4.40e-0515018962d0d6dc07dcfe28e3d7694c52d15d17dae2fd47b
ToppCellVE-CD8-memory_CD4|VE / Condition, Cell_class and T cell subcluster

SYNE2 ACBD5 USP43 PIANP PLEKHG3 ZBTB11

4.73e-0515218969401b7770c1bdc87eba25e82922f5dd1c4fa37ee
ToppCell390C-Lymphocytic-NK_cells-NK_cell_E|390C / Donor, Lineage, Cell class and subclass (all cells)

CUL7 EID2 DPF3 TTLL11 PCNX1 GOLGA8A

5.28e-05155189698d8432739965dd1ab77c899cb6321f7f05eaa46
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

SYNE2 HERC1 SMG6 PCNX1 IGSF1 GOLGA8A

5.47e-0515618961545169694f686d28648a68b552c2ae606599d66
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES SLC35F6 MPP2 LRRC4C GUCY1A1 CDH2

6.52e-05161189682ed45f144a07856fe92d37426c5f92e259a03a9
ToppCellfacs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DAB2IP BIRC7 XKR4 RECQL4 MTUS2 INSYN2A

7.22e-051641896cdb8cd2d6b369189ea77e4946738e2816d502e03
ToppCellfacs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DAB2IP BIRC7 XKR4 RECQL4 MTUS2 INSYN2A

7.22e-051641896f1423f4434af4af9c60c8a5b0b0abec4a7df9401
ToppCellfacs-Trachea-18m-Epithelial-glandular_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DAB2IP BIRC7 XKR4 RECQL4 MTUS2 INSYN2A

7.22e-0516418965dbfcdd450f652b16d97da53b528d4584b0eabcf
ToppCelldroplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ALDH1L1 F13A1 ITIH4 SNX29 ABCA6 PLEKHG3

7.46e-051651896354978d4f35154d7b2e36e94de669e045adef512
ToppCell368C-Lymphocytic-NK_cells-NK_cell_E|368C / Donor, Lineage, Cell class and subclass (all cells)

DOK7 CRACDL STAU2 RLIM SPEN NAIF1

8.52e-0516918960d96c0b4fd26fbc0bf44ff7bed2936eebcc55b74
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES CAAP1 BIN1 ANKFY1 MAN2B2 ZFPM2

8.52e-0516918967cb1b87be66a22fe5731bb1b55bc515920fe3e8b
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DAB2IP ANKFY1 ZNF407 PLEKHG4B RPAP1 CEP170B

8.52e-051691896665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DAB2IP ANKFY1 ZNF407 PLEKHG4B RPAP1 CEP170B

8.52e-0516918966614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

OBSCN F13A1 ANKRD2 MTUS2 DPF3 CDH2

8.80e-0517018963f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellTCGA-Prostate-Solid_Tissue_Normal-Prostate_normal_tissue-Prostate_normal_tissue-4|TCGA-Prostate / Sample_Type by Project: Shred V9

MPP2 MAMLD1 KIAA1614 MICALL1 ZNF488 IGSF1

9.09e-051711896cafcb7714110cb361808dbe4b9a4963bb71f5129
ToppCellCOVID_vent-Lymphocytic-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

TMEM17 MAP1A AXL GSN PLEKHG4B LTK

9.09e-051711896debbb071d260639b16269c94d172766908325c58
ToppCellCOVID_vent-Lymphocytic-Dendritic-pDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

TMEM17 MAP1A AXL GSN PLEKHG4B LTK

9.09e-051711896779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCellHealthy_donor-MAIT|World / disease group, cell group and cell class (v2)

DAB2IP SYNE2 PLCB1 GTF3C1 LTK CDH2

9.38e-0517218966524eb2be1c78700ad367e62624a4d7eb48b54f0
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

VGLL1 TMEM139 COL12A1 DOK7 MALRD1 IGSF1

9.38e-0517218960be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell10x5'v1-week_12-13-Myeloid_macrophage-stroma-monocytoid_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

AXL F13A1 RYR1 PLBD2 KIAA1614 ABCA6

9.38e-0517218969befd44bce43eb5dc1fe3d2e44608f442cf74a47
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSPOP ZSWIM5 LRRC4C ZFPM2 GUCY1A1 PLEKHG3

9.68e-051731896d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

F13A1 TECPR2 OGFRL1 EID2 SLC45A2 IGSF21

9.68e-0517318968384d533a1071fc65a06e6d9f5f17d8ab00c3966
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PXDC1 ABCA6 STAU2 ZNF488 IGSF21 XKR5

9.68e-0517318962b448acd5e584f24567204c31b8d74715e92f32a
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSPOP ZSWIM5 LRRC4C ZFPM2 GUCY1A1 PLEKHG3

9.68e-0517318963c852ffe22f4a5b632463086b08c669310684e80
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PXDC1 ABCA6 STAU2 ZNF488 IGSF21 XKR5

9.68e-0517318965086edc29c5a6137ca09877929a1317f9739c801
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NES SYN3 PLEKHG1 TCTE1 RASGRF2 CRACDL

1.00e-0417418963d4c05ea5719ca65e85d1f15198453034791087c
ToppCell10x5'-blood-Myeloid_Dendritic|blood / Manually curated celltypes from each tissue

AXL CTTNBP2NL GSN PLEKHG4B CD1D PCDHGB4

1.03e-0417518961c48eec300d5a6d4a810947b995af3b8c0a5a601
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ALDH1L1 CDKL5 AOC2 ARFGEF3 MB21D2 DPF3

1.03e-04175189696219e58dcb327fd27190be78193e7a0d611e62b
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ALDH1L1 CDKL5 AOC2 ARFGEF3 MB21D2 DPF3

1.03e-041751896cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NHSL2 ZFPM1 PCDH12 PLBD2 GIMAP8 MDC1

1.03e-04175189643be63976da5ad0764d24d90919a77ce46068f52
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYN3 NHSL2 LCA5 RASGRF2 ZFPM2 CRACDL

1.06e-041761896c7be4eaa5eb76ad9389fb9d15ad0934e88d267d1
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AXL SSPOP MPP2 LRRC4C GUCY1A1 CDH2

1.06e-041761896f931192e3cc65414e2245354f443473696cc7ce8
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AXL SSPOP MPP2 LRRC4C GUCY1A1 CDH2

1.06e-041761896e2b59a904c5c8f9c88e1e63788e9b6485f22edd0
ToppCellCOVID-19-Myeloid-MoAM4|COVID-19 / Condition, Lineage and Cell class

AXL PXDC1 F13A1 RYR1 GSN GUCY1A1

1.10e-041771896ca5d0c3d5c700bbe4c2da068eb02be6229afb9a0
ToppCellfacs-Heart-RV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC MPP2 PCDHGA4 LRRC4C TTLL11 CEP170B

1.10e-0417718967c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCellfacs-Heart-RV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC MPP2 PCDHGA4 LRRC4C TTLL11 CEP170B

1.10e-041771896e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYN3 NHSL2 LCA5 RASGRF2 ZFPM2 CRACDL

1.10e-0417718968b003ed7887479c3a010ef37dd981b748256bda7
DiseaseS-warfarin to R-warfarin ratio measurement

F13A1 LRRC4C ZFPM2 ARFGEF3 DPF3 ROBO1

2.32e-05951766EFO_0803331
Diseasetumor necrosis factor receptor superfamily member EDAR measurement

ZFPM1 RUNX1 ZFPM2

4.41e-05121763EFO_0008310
DiseaseColorectal Carcinoma

BOC TET2 OBSCN ALDH1L1 CSMD3 CDKL5 TTLL10 AMTN RASGRF2 RTN4 RPAP1 ABCA6 ARHGEF1 IGSF21

8.76e-0570217614C0009402
DiseaseSarcomatoid Renal Cell Carcinoma

TET2 BIRC7 CUL7 CSMD3 RYR1 SYNE2

1.23e-041281766C1266043
DiseaseChromophobe Renal Cell Carcinoma

TET2 BIRC7 CUL7 CSMD3 RYR1 SYNE2

1.23e-041281766C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

TET2 BIRC7 CUL7 CSMD3 RYR1 SYNE2

1.23e-041281766C1266044
DiseasePapillary Renal Cell Carcinoma

TET2 BIRC7 CUL7 CSMD3 RYR1 SYNE2

1.23e-041281766C1306837
DiseaseRenal Cell Carcinoma

TET2 BIRC7 CUL7 CSMD3 RYR1 SYNE2

1.23e-041281766C0007134
Diseasealkaline phosphatase measurement

TET2 ZBTB20 MAP1A ZFPM1 SLC30A1 ITIH4 RECQL4 HSPA4 DCDC2 DNAJC13 DOK7 USP43 RUNX1 ATXN1L KIAA1614 GSN ABCA6

1.30e-04101517617EFO_0004533
Diseaseplatelet component distribution width

TMEM17 ZFPM1 SLC30A1 EXD3 PLCB1 HERC1 MAMLD1 WBP2NL SIN3A ZFPM2 MICALL1 PLEKHG3 TLN1 TGS1

1.86e-0475517614EFO_0007984
DiseaseMyopathy, Centronuclear, Autosomal Recessive

RYR1 BIN1

2.11e-0441762C0410204
DiseaseParaparesis, Spastic

TECPR2 ABCD1

2.11e-0441762C0037771
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

TET2 BIRC7 CUL7 CSMD3 RYR1 SYNE2

2.71e-041481766C0279702
Diseasecoronary artery disease

DAB2IP TET2 CAAP1 ZBTB20 SYN3 ZFPM1 XKR4 F13A1 ITIH4 PLEKHG1 EHBP1L1 SMG6 DNAJC13 DOK7 USP43 ZFPM2 MALRD1 GUCY1A1

2.98e-04119417618EFO_0001645
Diseaseschizophrenia, sex interaction measurement

MPP2 ANKFY1 ABCA6 RNF111

4.60e-04601764EFO_0008343, MONDO_0005090
Diseasehypertension, COVID-19

PLEKHG1 PLCB1 GUCY1A1

5.49e-04271763EFO_0000537, MONDO_0100096
DiseaseHematopoetic Myelodysplasia

TET2 PLCB1 RUNX1

6.80e-04291763C2713368
Diseasemyelodysplastic syndrome (is_implicated_in)

TET2 PLCB1 ZFPM2

7.52e-04301763DOID:0050908 (is_implicated_in)
Diseasecreatinine measurement

TET2 SIPA1L3 OBSCN ALDH1L1 F13A1 RYR1 CDKL5 DCDC2 DNAJC13 SIN3A KIAA1614 CELSR3 DPF3 PCDHGB4 IGSF21

9.61e-0499517615EFO_0004518
Diseasesmoking behavior

CAAP1 ZBTB20 ITIH4 SMG6 RASGRF2 ZNF407 LRRC4C MICALL1

1.06e-033411768EFO_0004318
Diseaseinsomnia measurement

TET2 MFSD6 CSMD3 EXD3 MTUS2 MPP2 RASGRF2 LIN28B SNX29

1.43e-034431769EFO_0007876
Diseasesevere acute respiratory syndrome, COVID-19

CRNN MAMLD1 LRRC4C HELQ ZFPM2 MICALL1 ARHGAP6 MALRD1 GOLGA8A

1.52e-034471769EFO_0000694, MONDO_0100096
DiseaseKunitz-type protease inhibitor 2 measurement

SIPA1L3 RYR1

1.54e-03101762EFO_0008200
DiseaseC-X-C motif chemokine 5 measurement

ZFPM1 ZFPM2

1.54e-03101762EFO_0008058
Diseasebasophil percentage of granulocytes

ZFPM1 RYR1 ZNF469 RUNX1

1.56e-03831764EFO_0007995
Diseaselactate measurement

PNMA5 PLCB1 ZFPM2

1.63e-03391763EFO_0007745
Diseaseplatelet crit

TET2 ZBTB20 MAP1A NHSL2 MFSD6 ZFPM1 PLCB1 SMG6 ACBD5 ZNF407 RUNX1 KIAA1614 ZFPM2 TLN1

1.78e-0395217614EFO_0007985
Diseasebrain-derived neurotrophic factor measurement

RUNX1 ZFPM2

1.88e-03111762EFO_0011018
Diseaseleft ventricular structural measurement

DAB2IP SYN3 SMG6 RUNX1

1.93e-03881764EFO_0008205
Diseasemicrophthalmia (implicated_via_orthology)

ARHGAP6 STAU2

2.24e-03121762DOID:10629 (implicated_via_orthology)
Diseasedisks large homolog 3 measurement

ZFPM1 ZFPM2

2.24e-03121762EFO_0802472
Diseasedickkopf‐related protein 1 measurement

ZFPM1 ZFPM2

2.24e-03121762EFO_0010620
Diseasehip geometry

MPP2 RUNX1 CDH2

2.31e-03441763EFO_0004685
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

TET2 RUNX1 SPEN

2.46e-03451763DOID:3748 (is_implicated_in)
Diseasecentral corneal thickness

TET2 ZNF469 SDC1 COL12A1 ZNF407 ABCA6 DPF3

2.64e-033091767EFO_0005213
DiseaseAutosomal Dominant Myotubular Myopathy

RYR1 BIN1

2.64e-03131762C3661489
DiseaseCentronuclear myopathy

RYR1 BIN1

2.64e-03131762C0175709
DiseaseX-linked centronuclear myopathy

RYR1 BIN1

2.64e-03131762C0410203
DiseaseModic type vertebral endplate changes

XKR4 MPP2

2.64e-03131762HP_0030775
DiseaseCOVID-19, coronary artery disease

AXL GUCY1A1

2.64e-03131762EFO_0001645, MONDO_0100096
DiseaseMyopathy, Centronuclear, 1

RYR1 BIN1

2.64e-03131762C4551952
Diseaselevel of Phosphatidylcholine (16:0_18:3) in blood serum

DOK7 RNF111

2.64e-03131762OBA_2045072
DiseaseCongenital Structural Myopathy

RYR1 BIN1

2.64e-03131762C0752282
DiseaseGastrointestinal Stromal Sarcoma

BOC TMEM17 ZBTB11

2.79e-03471763C3179349
DiseaseMyopathy, Centronuclear, Autosomal Dominant

RYR1 BIN1

3.07e-03141762C1834558
DiseaseTubular Aggregate Myopathy

RYR1 BIN1

3.07e-03141762C0410207
DiseaseSpastic Paraplegia, Hereditary

TECPR2 ABCD1

3.07e-03141762C0037773
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

DAB2IP SRCAP SIN3A

3.14e-03491763DOID:0060037 (implicated_via_orthology)
DiseaseGastrointestinal Stromal Tumors

BOC TMEM17 ZBTB11

3.33e-03501763C0238198
Diseasemyelodysplastic syndrome (implicated_via_orthology)

TET2 CREBBP

3.53e-03151762DOID:0050908 (implicated_via_orthology)
DiseaseAutosomal Recessive Centronuclear Myopathy

RYR1 BIN1

3.53e-03151762C3645536
Diseaseglucose metabolism measurement, age-related hearing impairment

DAB2IP CAAP1 ZNF469

3.72e-03521763EFO_0005782, EFO_0009367
DiseaseAlzheimer disease, educational attainment

TET2 MPP2 EFL1 BIN1 SNX29 TTLL11

3.76e-032471766EFO_0011015, MONDO_0004975
Diseaseretinal vasculature measurement

PLEKHG1 PLCB1 TTLL10 PIWIL2 LRRC4C MED13L MB21D2 PLEKHG3 SLC45A2

4.01e-035171769EFO_0010554
Diseaseinterferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement

MEN1 ZFPM2

4.02e-03161762EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
Diseasecolorectal mucinous adenocarcinoma

ZBTB20 RASGRF2

4.02e-03161762EFO_0009361
Diseasesuccinylcarnitine measurement

SYN3 SUCLG2

4.02e-03161762EFO_0020020
Diseasetestosterone measurement

TET2 ZBTB20 MAP1A NHSL2 SRCAP CSMD3 SYNE2 PLCB1 SDC1 EFL1 DOK7 DNAH2 USP43 SIN3A ZFPM2 ARHGAP6

4.16e-03127517616EFO_0004908
Diseasevascular endothelial growth factor measurement

ZFPM1 DNAH2 ZFPM2

4.59e-03561763EFO_0004762
Diseasecalcium measurement

TET2 MAP1A MFSD6 ZFPM1 EHBP1L1 SYNE2 DOK7 DNAH2 ZFPM2 ABCA6

4.61e-0362817610EFO_0004838
Diseaseskin aging measurement

ZBTB20 PGC SYNE2 ATXN1L SLC45A2

4.70e-031811765EFO_0008006
Diseaseneurofilament light chain measurement

NARF CD1D GOLGA8A

4.82e-03571763EFO_0009178
DiseaseBeta blocking agent use measurement

PLEKHG1 PLCB1 SMG6 GUCY1A1

4.91e-031141764EFO_0009929
Diseasepre-eclampsia (is_marker_for)

CREBBP GSN ROBO1

5.06e-03581763DOID:10591 (is_marker_for)
DiseaseUterine leiomyoma, estrogen-receptor positive breast cancer

HSPA4 ZFPM2

5.08e-03181762EFO_1000649, HP_0000131
Diseasenevus count

SLC30A1 SLC45A2

5.08e-03181762EFO_0004632
Diseaselevel of Phosphatidylcholine (20:4_0:0) in blood serum

DOK7 TGOLN2

5.08e-03181762OBA_2045110
DiseaseCongenital Fiber Type Disproportion

RYR1 BIN1

5.08e-03181762C0546264
DiseaseMalignant neoplasm of breast

BOC PXDC1 OBSCN MRPL19 SYNE2 PLCB1 RASGRF2 ZSWIM5 HELQ GSN MICALL1 ROBO1 SPEN CDH2

5.22e-03107417614C0006142
DiseaseAntihypertensive use measurement

MFSD6 PLEKHG1 PLCB1 SMG6 ZFPM2 GUCY1A1

5.28e-032651766EFO_0009927
Diseaseadverse effect, response to xenobiotic stimulus

CAAP1 SCAF4 PLCB1

5.31e-03591763EFO_0009658, GO_0009410
Diseaseintelligence, self reported educational attainment

TET2 EFL1 CELSR3 TTLL11

5.38e-031171764EFO_0004337, EFO_0004784
Diseasebasophil measurement

ZFPM1 ZNF469 RUNX1

5.56e-03601763EFO_0803539
Diseaseresponse to cranial radiation therapy, short-term memory

MPP2 LIN28B MALRD1

5.56e-03601763EFO_0004335, EFO_0010950
DiseasePost-Traumatic Osteoporosis

CALCR GSN TLN1

5.83e-03611763C0751406
DiseaseOsteoporosis, Senile

CALCR GSN TLN1

5.83e-03611763C0029459
DiseaseOsteoporosis, Age-Related

CALCR GSN TLN1

5.83e-03611763C0001787

Protein segments in the cluster

PeptideGeneStartEntry
NEGPESPTQAAQGLE

AMER3

266

Q8N944
DQDQQASGLQSPPSR

CTTNBP2NL

471

Q9P2B4
QNGPIDPENNRGQES

SMG6

106

Q86US8
DPENNRGQESFPRTA

SMG6

111

Q86US8
DRNIGAPGQDTPGVS

ARHGEF1

311

Q92888
PPQISNGRLEGTNFD

CSMD3

3236

Q7Z407
EPRNEPANNQGEESA

CALCR

446

P30988
ENSGFREDIQVPPGN

ACBD5

346

Q5T8D3
AQGQAPLEPTQDGSA

EFL1

456

Q7Z2Z2
LDEPSTGIDPTGQQQ

ABCA6

1436

Q8N139
GENVTLGDDPSQPQT

CREBBP

1246

Q92793
ESAQEPGGVSPAEAQ

BIRC7

211

Q96CA5
NVEDFQGVGESEPNP

AQR

1181

O60306
QAGANPDVQDGSLPA

AMTN

141

Q6UX39
APEAPENTVQSEAGQ

CAAP1

276

Q9H8G2
TEHAQLGEDGQQPPR

RAD54L2

56

Q9Y4B4
DDGSTLPDAQRQGEP

CEP170B

176

Q9Y4F5
GEQPSGEQASGEQPS

ACRV1

151

P26436
GDPTVGETNPRSIQN

ITIH4

386

Q14624
TQSGDSAQPEQGRPA

MTUS2

866

Q5JR59
VEGSSAPELNPNGNA

RAI2

96

Q9Y5P3
SVEQDGDEPGPQRSV

RBM8A

56

Q9Y5S9
GQSSVGRSQPRPEEE

TSPOAP1

756

O95153
LGNQPSPTAVAAGEE

INSYN2A

331

Q6ZSG2
EPVQGEAREGSPHDN

GOLGA8F;

381

Q08AF8
QVRASDPDLGPNGQV

PCDHGB4

471

Q9UN71
GPSARAGGQTDPEQE

PCDH12

1001

Q9NPG4
GEERPGEQSQGTQSQ

MEN1

391

O00255
DVTEGQRAGEPNSPD

NSUN2

731

Q08J23
QRAGEPNSPDAEEAN

NSUN2

736

Q08J23
LQAPAGEPTQEASGV

ABCD1

46

P33897
GPGLVDAAQAQPSDN

AOC2

76

O75106
VNSPRQPGANGEGEE

ANKFY1

751

Q9P2R3
DVNDNPPSFGTEQRE

PCDHGA4

156

Q9Y5G9
GPDVLPTDGQAAAAQ

DAB2IP

766

Q5VWQ8
QLPAQLRPGDQSDSG

TCTE1

201

Q5JU00
ESEQPAQPPEQAGGR

OGFRL1

46

Q5TC84
PATQRQDPAAAQEGE

GAGE1

46

P0DTW1
VVSGNDPANGEPSRA

MAP1A

2721

P78559
LSQQPGDSLGEVNDP

MED13L

701

Q71F56
GESTQPQREGAQVPT

MDC1

656

Q14676
QSDGGDPNQPDDRLA

MB21D2

441

Q8IYB1
DNPGPQAAEQGTDTA

HSPA4

811

P34932
PATQRQDPAAAQEGE

GAGE7

46

O76087
SDPGQVAQNGQPDSI

NAIF1

311

Q69YI7
EGDEAQDQETRSPPN

DPF3

226

Q92784
GSRVVEPSQPESGAQ

ATXN1L

631

P0C7T5
PDRGPAEAQTQAEGQ

MESP2

166

Q0VG99
SAEVVPNSEDQGPGA

MESP2

346

Q0VG99
ANENVSPGIPSAEEQ

ZFPM2

1086

Q8WW38
PATQRQDPAAAQEGE

GAGE2E

46

Q4V326
EGRAEPEPPQAQQGS

FER1L4

351

A9Z1Z3
GARADDPPPQSQQER

HERC1

1411

Q15751
APRTQNLPDGQLDGS

KIAA1614

141

Q5VZ46
QPPASSQGRQEAESQ

LIN28B

171

Q6ZN17
DPSGRQGELSPVEDQ

EPSTI1

26

Q96J88
APSPQAGRSLQEGAE

LTK

281

P29376
ANEFTSQGDRPPGNT

PCNX1

496

Q96RV3
SQGDRPPGNTAENKE

PCNX1

501

Q96RV3
QPGSPAINGRSQTDD

KXD1

156

Q9BQD3
DEGEFRQSNNGVPPV

CUL7

396

Q14999
ARAEPLAQNGGSSEP

ZFPM1

441

Q8IX07
EGQGRPQQAVASPSN

EHBP1L1

226

Q8N3D4
GDDTGAPHSPQERDQ

HEATR6

1116

Q6AI08
EPGGQRQEASTGQSP

NES

446

P48681
QSEVSGENEGNLPSP

KIF24

966

Q5T7B8
DNEGSPPSEQLVQDG

KIF24

1061

Q5T7B8
GRRAVPPNNSNAAED

F13A1

11

P00488
GQNSGNVRSPASPNE

LCA5

536

Q86VQ0
QVENGGTEEVAQPSP

MICALL1

401

Q8N3F8
QDEARTTDNNVGPTP

LRRC4C

466

Q9HCJ2
EVNGQPVGSDPRALQ

MPP2

211

Q14168
TNENRENSPAGRAQP

MFSD6

726

Q6ZSS7
QGEAREGSPRDNPTA

GOLGA2

946

Q08379
SSSNQQDPGEPGEAE

HUWE1

2286

Q7Z6Z7
QGRSDGSGESAQPPE

HUWE1

2901

Q7Z6Z7
ERPSSGQQDVAPDRG

CRACDL

276

Q6NV74
SNPEAGETVPGGQAQ

CRNN

391

Q9UBG3
GVQENSPAQQAGLEP

GORASP1

21

Q9BQQ3
QPSAPESRQVAAGED

OBSCN

4626

Q5VST9
PEGVETPTDQGGQAA

ARHGAP6

901

O43182
REIPAFESTPQQDQG

MALRD1

296

Q5VYJ5
EEQQDGASSRSPPGD

BECN2

56

A8MW95
NGLEGPNDSGRETPQ

ANKRD2

341

Q9GZV1
EEGPQVGPSAAQTLR

ADAMTS4

276

O75173
FENPNIPRGTEDSNG

IGSF21

431

Q96ID5
EECNQEGEPGTPANS

IGSF1

1306

Q8N6C5
EPVQGEAREGSPHDN

GOLGA8DP

381

Q0D2H9
QQIQRDDPGASPQSS

BOC

581

Q9BWV1
AGGESREVTTPPNQR

COL12A1

761

Q99715
PATQRQDPAAAQEGE

GAGE12F

46

P0CL80
PATQRQDPAAAQEGE

GAGE12G

46

P0CL81
PATQRQDPAAAQEGE

GAGE12I

46

P0CL82
PATQRQDPAAAQEGE

GAGE12J

46

A6NER3
QGTQPGDILPNADET

CD1D

246

P15813
PATQRQDPAAAQEGE

GAGE6

46

Q13070
PDVPQDFGNQGSTVE

ARFGEF3

186

Q5TH69
ISQDQPPGDNARSQV

CENPJ

891

Q9HC77
NEAASQEGDKPQGPR

GIMAP8

216

Q8ND71
TLVQQAAAGPEGAPE

GLI4

146

P10075
EVTPGGFDQINPATN

DNAJC13

131

O75165
PQTGAANGDRDVPQA

EID2

11

Q8N6I1
GNSFTSRQDPQPGDV

MAMLD1

661

Q13495
NIRPTAGAQEGTQEP

MAN2B2

541

Q9Y2E5
RAQPVQVAEGSEPDG

GSN

626

P06396
PATQRQDPAAAQEGE

GAGE13

46

Q4V321
AAAAVEGQRQPESSP

EN2

11

P19622
QEGPRPAAAQAAGEA

DOK7

296

Q18PE1
PTDRGVGDQPNDSEV

HELQ

91

Q8TDG4
SDQGQEPGPRSATVR

CELSR3

516

Q9NYQ7
PATQRQDPAAAQEGE

GAGE5

46

Q13069
AQPAEASEVAGGTQP

BIN1

456

O00499
QASGGSSNIRQEPAP

CDKL5

881

O76039
ATQEQGNAPAVSEPE

DNAH2

31

Q9P225
AAPVAENVTNNEGSP

SCAF4

141

O95104
ERQQAPGGDPDNSVR

SLC45A2

456

Q9UMX9
PQAGGEAQPARAENE

RYR1

1361

P21817
DPTGRFAIQTDPNSN

CDH2

426

P19022
AGSGQDEADVDPQRP

DCDC2

436

Q9UHG0
QRAGNDPPGVSNASE

KRBA2

86

Q6ZNG9
SERGNDQESSQPVGP

PAGE5

31

Q96GU1
EGAQPNTENGVPEIT

FAM114A1

171

Q8IWE2
AAGQGAERDVPDPQQ

NUTM2B

651

A6NNL0
EAREGSSQDNPTAQP

GOLGA8A

581

A7E2F4
NPSLPNQSDVVEAEG

RUNX1

416

Q01196
EHGPGLENRQDPSQE

RUSC1

76

Q9BVN2
EQPGNTISAGQEDFP

RTN4

211

Q9NQC3
EPASGGEQEPRPQQA

SYTL1

196

Q8IYJ3
RPPVQGRSTSQQGEE

SYN3

511

O14994
SIPNGRDQQLGVDPT

PXDC1

176

Q5TGL8
RGPVPGDLSQTSEDQ

SNX29

631

Q8TEQ0
AEGNPQPSEEGVSQE

TCEAL8

31

Q8IYN2
QPSEEGVSQEAEGNP

TCEAL8

36

Q8IYN2
GPGVAPCQAQDTEQR

SSPOP

4796

A2VEC9
DVPDSILSPQGQNGD

SYNE2

4436

Q8WXH0
SGTQQPPQGSVEDEG

NHSL2

961

Q5HYW2
EGSRDPADPSQQGRV

PLEKHG3

1191

A1L390
EPSTQRGPAQRESVG

PIWIL2

56

Q8TC59
EQSPGTVEENVDNPR

RASGRF2

796

O14827
AQQLPEDPGQGSSSV

RECQL4

971

O94761
RNSSPGLPDVAESQG

SLC26A8

691

Q96RN1
TVSREDGGDPNSANP

PIANP

111

Q8IYJ0
PATQRQDPAAAQEGE

GAGE4

46

P0DSO3
DNLGPEQERDTGQSP

SIPA1L3

1521

O60292
QEQATEENAGVPVGP

SIN3A

761

Q96ST3
EPDRRNQSPVDQGAT

SDC1

226

P18827
EQEGVQRPPRGSQSA

SPATA31E1

926

Q6ZUB1
PEGPSAEAQGGSQQE

SCRIB

536

Q14160
QIGGEFSNTPDQAPE

SNAPC3

226

Q92966
LEAGSIPNGQEQEAP

SRCAP

2611

Q6ZRS2
VGNPLDRDTDHGPQN

ALDH1L1

736

O75891
NQTPGREGPQAAGEE

PNMA5

416

Q96PV4
VRQQSTGPSEPGAFQ

MRPL19

41

P49406
DSNRTGPESNEGPEN

TMEM17

21

Q86X19
VPNPAQEDSNSDGVG

THBS4

686

P35443
GAEAQTPEDSPNRSG

TGOLN2

141

O43493
PQGGVDIEEVAASNP

SUCLG2

171

Q96I99
APSGENEAESRQGPD

TRIM24

26

O15164
APAQPSAAEEGNTQV

TTLL11

156

Q8NHH1
RSENLEQVPQDGSPN

USPL1

916

Q5W0Q7
PRSNVALPANSEDGG

USP43

866

Q70EL4
QAQEREHDDPTGQPG

ZNF488

116

Q96MN9
QNGEVGRQPEPQVSS

ZBTB11

376

O95625
SEINQVNGAPDPTAG

ZSWIM5

311

Q9P217
GESQTDLQPPAGAQA

SPEN

2241

Q96T58
PNQEFGLSENEPGTN

PGC

156

P20142
QNNPAVPSGSIDEDV

RNF111

286

Q6ZNA4
NEPIPERSPQNGESG

STAU2

181

Q9NUL3
DPNSQAGQQGLVEPT

TLN1

1451

Q9Y490
TQEETSGPRGDPQQT

PLEKHG4B

41

Q96PX9
PPQNSDENRGGDSSD

RLIM

76

Q9NVW2
ISQEEPQGEATPVGN

ZSCAN5B

306

A6NJL1
TPVGNRESPGQAEIN

ZSCAN5B

316

A6NJL1
VQGPDPGTEEQLSQD

ZSCAN25

171

Q6NSZ9
GARPQESTAAQAPEN

WBP2NL

281

Q6ICG8
QAEESPFVGNPGNIT

AXL

31

P30530
AAGEGEARPSTPQRQ

XKR4

201

Q5GH76
RFDGQPINETDTPAQ

SUMO2

61

P61956
GDQGPAVRQANSSVP

USF3

1961

Q68DE3
NGEVNGVPQENTDPE

TECPR2

531

O15040
NPGDPREAQEQQNDG

ROBO1

1546

Q9Y6N7
ASEEQRPGGPSANVT

RPAP1

276

Q9BWH6
AGSANETPEIPDNVG

TOMM6

11

Q96B49
APSEARTTPAENGVN

PLCB1

851

Q9NQ66
RAAGQSDSSVDPQQP

SLC35F6

71

Q8N357
AVNGSNPEGEDPERE

ZNF200

156

P98182
EPDSVEQQFGPGAAR

ZBTB20

386

Q9HC78
QAAEAPAEGGPQTNQ

ZBTB20

411

Q9HC78
PAEGGPQTNQLETGA

ZBTB20

416

Q9HC78
NQLQPENGVSPGGTD

ZNF469

1971

Q96JG9
NPQPNGENAISARSD

PLBD2

496

Q8NHP8
QQNADEGSERPPRAQ

PLEKHG1

76

Q9ULL1
NSGLSQTDPENPDLG

PLEKHG1

951

Q9ULL1
TQEAEQGQGSARPPD

ZNF407

496

Q9C0G0
GQSEPRNGGTNEESN

TGS1

361

Q96RS0
DEAPTQNPAATQGEG

XKR5

496

Q6UX68
NVAPGEQGPDQEETN

SLC30A1

176

Q9Y6M5
EQLSGQAQPPEGSED

GTF3C1

1941

Q12789
GVSQERNPGESSQPN

TET2

126

Q6N021
EPQAPGTEQSGTGNR

TTLL10

636

Q6ZVT0
PQESAARENGNPGQI

VGLL1

181

Q99990
PGSSQRSPEAAGVQD

UCN

21

P55089
ATPVGNRESPGQAEI

ZSCAN5C

316

A6NGD5
QTESPGPSGNARDNE

TMEM139

71

Q8IV31
QAAPAVEAEGPGSSQ

TXLNA

36

P40222
APGQVPNESSEEAAG

GUCY1A1

21

Q02108
ENVSADAPSPAQENG

NARF

21

Q9UHQ1
DEATQSQAVQEPGPA

EXD3

761

Q8N9H8
QARVQGQRPGSPEEA

MZF1

101

P28698