Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

CCDC170 MYH11 DST KIF27 PPP5C CENPF SYNE2 GBP1 GBP3 SPIRE1 INO80 NEB TNNT2 MAP10 KLC3 HSP90AA1 TTLL7

5.19e-0610998817GO:0008092
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DOCK1 DOCK5 RASA2 DOCK8 RABEP1 DOCK9 GBP1 GBP3 AKAP13 RGS9 PREX2

1.39e-055078811GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

DOCK1 DOCK5 RASA2 DOCK8 RABEP1 DOCK9 GBP1 GBP3 AKAP13 RGS9 PREX2

1.39e-055078811GO:0030695
GeneOntologyMolecularFunctiontubulin binding

CCDC170 DST KIF27 PPP5C CENPF SPIRE1 INO80 MAP10 KLC3 TTLL7

1.87e-054288810GO:0015631
GeneOntologyMolecularFunctionmicrotubule binding

CCDC170 DST KIF27 PPP5C CENPF SPIRE1 MAP10 KLC3

6.45e-05308888GO:0008017
GeneOntologyMolecularFunctionactin binding

MYH11 DST SYNE2 GBP1 GBP3 SPIRE1 INO80 NEB TNNT2

2.60e-04479889GO:0003779
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK1 DOCK5 DOCK8 DOCK9 AKAP13 PREX2

5.52e-04231886GO:0005085
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

DNAH12 KIF27 SEPTIN9 GBP1 GBP3 RGS9 INO80 DDX39B ATP10D HSP90AA1 RAD50

5.90e-047758811GO:0017111
GeneOntologyMolecularFunctionU4 snRNA binding

SART3 DDX39B

6.78e-049882GO:0030621
GeneOntologyMolecularFunctionpyrophosphatase activity

DNAH12 KIF27 SEPTIN9 GBP1 GBP3 RGS9 INO80 DDX39B ATP10D HSP90AA1 RAD50

1.13e-038398811GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

DNAH12 KIF27 SEPTIN9 GBP1 GBP3 RGS9 INO80 DDX39B ATP10D HSP90AA1 RAD50

1.14e-038408811GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

DNAH12 KIF27 SEPTIN9 GBP1 GBP3 RGS9 INO80 DDX39B ATP10D HSP90AA1 RAD50

1.14e-038408811GO:0016818
GeneOntologyMolecularFunctionGDP phosphatase activity

GBP1 GBP3

1.23e-0312882GO:0004382
GeneOntologyMolecularFunctionenzyme regulator activity

DOCK1 DOCK5 RASA2 DOCK8 SERPINB4 RABEP1 DOCK9 OTUB1 GBP1 GBP3 AKAP13 RGS9 PREX2 HSP90AA1 RAD50

1.27e-0314188815GO:0030234
GeneOntologyMolecularFunctionGTPase activator activity

DOCK1 DOCK5 RASA2 RABEP1 RGS9 PREX2

1.47e-03279886GO:0005096
GeneOntologyMolecularFunctionATP-dependent activity

MYH11 DNAH12 KIF27 INO80 TNNT2 DDX39B ATP10D HSP90AA1 RAD50

1.53e-03614889GO:0140657
GeneOntologyMolecularFunctionHsp90 protein binding

PPP5C GBP1 GBP3

1.84e-0355883GO:0051879
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH11 DNAH12 KIF27 TNNT2

1.84e-03118884GO:0003774
GeneOntologyBiologicalProcessorganelle assembly

DOCK5 PATL2 CLUAP1 MYH11 NPHP3 KIF27 MNS1 CENPF SEPTIN9 SYNE2 OGFOD1 PTPN23 CASQ1 AKAP13 INO80 NEB TNNT2 MAP10 KLC3

1.71e-0711388619GO:0070925
GeneOntologyBiologicalProcessmembraneless organelle assembly

DOCK5 PATL2 MYH11 CENPF OGFOD1 CASQ1 AKAP13 INO80 NEB TNNT2 MAP10

4.45e-064758611GO:0140694
GeneOntologyBiologicalProcessmyofibril assembly

MYH11 CASQ1 AKAP13 NEB TNNT2

2.99e-0586865GO:0030239
GeneOntologyBiologicalProcessstriated muscle cell development

MYH11 CASQ1 AKAP13 NEB TNNT2

3.53e-0589865GO:0055002
GeneOntologyBiologicalProcessstriated muscle cell differentiation

DOCK1 DOCK5 MYH11 NEK5 CASQ1 AKAP13 NEB TNNT2 DDX39B

3.66e-05391869GO:0051146
GeneOntologyBiologicalProcesscellular anatomical entity morphogenesis

PALS1 MYH11 CASQ1 AKAP13 NEB TNNT2

4.85e-05156866GO:0032989
GeneOntologyBiologicalProcesscellular component assembly involved in morphogenesis

PALS1 MYH11 CASQ1 AKAP13 NEB TNNT2

4.85e-05156866GO:0010927
GeneOntologyBiologicalProcesspositive regulation of DNA metabolic process

IFNG MORF4L1 SPIRE1 INO80 DDX39B HSP90AA1 MAP3K4 RAD50

7.54e-05333868GO:0051054
GeneOntologyBiologicalProcessmicrotubule-based transport

CLUAP1 NPHP3 DST KIF27 SYNE2 FYCO1 KLC3

9.06e-05253867GO:0099111
GeneOntologyBiologicalProcesspositive regulation of AIM2 inflammasome complex assembly

GBP1 GBP3

1.03e-044862GO:0140973
GeneOntologyBiologicalProcesssarcomere organization

CASQ1 AKAP13 NEB TNNT2

1.08e-0459864GO:0045214
GeneOntologyBiologicalProcessmicrotubule-based process

CCDC170 CLUAP1 NPHP3 DNAH12 DST KIF27 MNS1 SYNE2 SPIRE1 FYCO1 INO80 MAP10 KLC3 TTLL7

1.15e-0410588614GO:0007017
GeneOntologyBiologicalProcessmicrotubule-based movement

CLUAP1 NPHP3 DNAH12 DST KIF27 MNS1 SYNE2 FYCO1 KLC3

2.13e-04493869GO:0007018
GeneOntologyBiologicalProcessregulation of AIM2 inflammasome complex assembly

GBP1 GBP3

2.55e-046862GO:0140971
GeneOntologyCellularComponentsupramolecular fiber

MYH11 DNAH12 DST KIF27 MNS1 SEPTIN9 SYNE2 CASQ1 PYGM AKAP13 LTBP1 INO80 NEB TNNT2 MAP10 KLC3 TTLL7

6.12e-0611798717GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

MYH11 DNAH12 DST KIF27 MNS1 SEPTIN9 SYNE2 CASQ1 PYGM AKAP13 LTBP1 INO80 NEB TNNT2 MAP10 KLC3 TTLL7

6.69e-0611878717GO:0099081
GeneOntologyCellularComponentactin cytoskeleton

DOCK5 MYH11 DST SEPTIN9 ANKRD26 GBP1 GBP3 AKAP13 RAI14 NEB TNNT2

2.66e-055768711GO:0015629
GeneOntologyCellularComponentcilium

CCDC170 CLUAP1 NPHP3 DNAH12 KIF27 MNS1 CENPF SEPTIN9 PTPN23 CCDC178 KLC3 HSP90AA1 TTLL7

8.37e-058988713GO:0005929
GeneOntologyCellularComponentperinuclear region of cytoplasm

DST RASA2 CENPF SEPTIN9 GBP1 GBP3 SPIRE1 AKAP13 LTBP1 HSP90AA1 MAP3K4 FBXL5 RAD50

1.24e-049348713GO:0048471
GeneOntologyCellularComponentcontractile muscle fiber

MYH11 DST SYNE2 CASQ1 PYGM NEB TNNT2

2.08e-04290877GO:0043292
GeneOntologyCellularComponenthost cell part

GBP1 GBP3

2.54e-046872GO:0033643
GeneOntologyCellularComponenthost intracellular part

GBP1 GBP3

2.54e-046872GO:0033646
GeneOntologyCellularComponenthost cell cytoplasm part

GBP1 GBP3

2.54e-046872GO:0033655
GeneOntologyCellularComponentsymbiont-containing vacuole

GBP1 GBP3

2.54e-046872GO:0020003
GeneOntologyCellularComponentsymbiont-containing vacuole membrane

GBP1 GBP3

2.54e-046872GO:0020005
GeneOntologyCellularComponenthost intracellular region

GBP1 GBP3

2.54e-046872GO:0043656
GeneOntologyCellularComponenthost cell cytoplasm

GBP1 GBP3

2.54e-046872GO:0030430
GeneOntologyCellularComponentmicrotubule

DNAH12 DST KIF27 MNS1 SEPTIN9 INO80 MAP10 KLC3 TTLL7

3.74e-04533879GO:0005874
GeneOntologyCellularComponentZ disc

DST SYNE2 CASQ1 PYGM NEB

4.22e-04151875GO:0030018
GeneOntologyCellularComponentsymbiont cell surface

GBP1 GBP3

4.72e-048872GO:0106139
GeneOntologyCellularComponentother organism part

GBP1 GBP3

6.05e-049872GO:0044217
GeneOntologyCellularComponentsarcomere

DST SYNE2 CASQ1 PYGM NEB TNNT2

6.07e-04249876GO:0030017
GeneOntologyCellularComponentI band

DST SYNE2 CASQ1 PYGM NEB

6.50e-04166875GO:0031674
GeneOntologyCellularComponentmyofibril

DST SYNE2 CASQ1 PYGM NEB TNNT2

9.79e-04273876GO:0030016
GeneOntologyCellularComponentcontractile actin filament bundle

MYH11 DST SEPTIN9 RAI14

1.04e-03107874GO:0097517
GeneOntologyCellularComponentstress fiber

MYH11 DST SEPTIN9 RAI14

1.04e-03107874GO:0001725
GeneOntologyCellularComponentsarcoplasm

SYNE2 CASQ1 PYGM TNNT2

1.32e-03114874GO:0016528
GeneOntologyCellularComponentciliary basal body

CCDC170 CENPF PTPN23 CCDC178 TTLL7

1.34e-03195875GO:0036064
GeneOntologyCellularComponentactomyosin

MYH11 DST SEPTIN9 RAI14

1.45e-03117874GO:0042641
GeneOntologyCellularComponentactin filament bundle

MYH11 DST SEPTIN9 RAI14

1.50e-03118874GO:0032432
GeneOntologyCellularComponenthost cellular component

GBP1 GBP3

1.74e-0315872GO:0018995
GeneOntologyCellularComponentperikaryon

IFNG PALS1 PPP5C ASTN2 TTLL7

2.40e-03223875GO:0043204
GeneOntologyCellularComponentlamellipodium membrane

DOCK8 SYNE2

3.75e-0322872GO:0031258
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

DNAH12 DST KIF27 MNS1 SEPTIN9 AKAP13 INO80 MAP10 KLC3 TTLL7

4.12e-038998710GO:0099513
GeneOntologyCellularComponentcell cortex

DST SEPTIN9 SPIRE1 ASTN2 AKAP13 RAI14

4.54e-03371876GO:0005938
MousePhenoabnormal sarcomere morphology

MYH11 DST CASQ1 AKAP13 NEB TNNT2

2.91e-0677736MP:0004090
MousePhenolethality throughout fetal growth and development

SEL1L DOCK1 NCOR2 CLUAP1 MORF4L1 OTUB1 LTBP1 AIP PBX1 MAP3K4 RAD50

1.46e-054357311MP:0006208
MousePhenoincreased susceptibility to parasitic infection induced morbidity/mortality

IFNG GBP1 GBP3

2.19e-0511733MP:0010750
MousePhenodiffuse hepatic necrosis

IFNG MME

8.04e-053732MP:0005151
DomainDOCK_C

DOCK1 DOCK5 DOCK8 DOCK9

1.29e-0711854IPR010703
DomainDHR-1_domain

DOCK1 DOCK5 DOCK8 DOCK9

1.29e-0711854IPR027007
DomainDHR_2

DOCK1 DOCK5 DOCK8 DOCK9

1.29e-0711854PS51651
DomainDHR_1

DOCK1 DOCK5 DOCK8 DOCK9

1.29e-0711854PS51650
DomainDOCK-C2

DOCK1 DOCK5 DOCK8 DOCK9

1.29e-0711854PF14429
DomainDHR-2

DOCK1 DOCK5 DOCK8 DOCK9

1.29e-0711854IPR027357
DomainDHR-2

DOCK1 DOCK5 DOCK8 DOCK9

1.29e-0711854PF06920
DomainDOCK

DOCK1 DOCK5 DOCK8 DOCK9

1.29e-0711854IPR026791
DomainDUF3496

ANKRD26 CCDC144A

6.12e-053852IPR021885
DomainDUF3496

ANKRD26 CCDC144A

6.12e-053852PF12001
DomainTPR-like_helical_dom

SEL1L SART3 NPHP3 PPP5C AIP KLC3 CRTAP

9.29e-05233857IPR011990
DomainDOCK_N

DOCK1 DOCK5

2.03e-045852PF16172
DomainDOCK_N

DOCK1 DOCK5

2.03e-045852IPR032376
DomainDUF3398

DOCK8 DOCK9

3.03e-046852PF11878
DomainRab5-bind

RABEP1 KLC3

3.03e-046852PF09311
DomainRabaptin_Rab5-bd_dom

RABEP1 KLC3

3.03e-046852IPR015390
DomainDOCK_C/D_N

DOCK8 DOCK9

3.03e-046852IPR021816
Domain-

SEL1L NPHP3 PPP5C AIP KLC3 CRTAP

3.64e-042078561.25.40.10
DomainTPR-contain_dom

NPHP3 PPP5C PTPN23 AIP KLC3

6.12e-04150855IPR013026
DomainGBP_C

GBP1 GBP3

9.00e-0410852PF02841
DomainTPR_REGION

NPHP3 PPP5C PTPN23 AIP KLC3

9.40e-04165855PS50293
DomainTPR

NPHP3 PPP5C PTPN23 AIP KLC3

9.40e-04165855PS50005
DomainMACPF

ASTN2 C8A

1.10e-0311852PF01823
DomainG_GB1_RHD3_dom

GBP1 GBP3

1.10e-0311852IPR030386
DomainGuanylate-bd_C

GBP1 GBP3

1.10e-0311852IPR003191
DomainGBP

GBP1 GBP3

1.10e-0311852PF02263
DomainGuanylate-bd_N

GBP1 GBP3

1.10e-0311852IPR015894
DomainG_GB1_RHD3

GBP1 GBP3

1.10e-0311852PS51715
DomainMACPF

ASTN2 C8A

1.31e-0312852SM00457
DomainMACPF

ASTN2 C8A

1.31e-0312852IPR020864
DomainTPR_2

NPHP3 AIP KLC3

1.53e-0350853PF07719
DomainTPR_2

NPHP3 AIP KLC3

1.53e-0350853IPR013105
DomainP-loop_NTPase

PALS1 MYH11 NPHP3 DNAH12 KIF27 SEPTIN9 GBP1 GBP3 INO80 DDX39B RAD50

1.57e-038488511IPR027417
DomainFN_type2_col-bd

SEL1L LY75

1.80e-0314852IPR000562
DomainFN2_2

SEL1L LY75

1.80e-0314852PS51092
Domainfn2

SEL1L LY75

1.80e-0314852PF00040
DomainFN2_1

SEL1L LY75

1.80e-0314852PS00023
DomainFN2

SEL1L LY75

1.80e-0314852SM00059
DomainSH3

DOCK1 DOCK5 PALS1 DST NEB

3.06e-03216855PS50002
DomainTPR_repeat

NPHP3 PPP5C AIP KLC3

3.19e-03133854IPR019734
DomainSH3_domain

DOCK1 DOCK5 PALS1 DST NEB

3.31e-03220855IPR001452
DomainEGF_3

STAB2 FAT3 ASTN2 LTBP1 C8A

4.38e-03235855PS50026
DomainDEP

RGS9 PREX2

4.46e-0322852PF00610
DomainDEP

RGS9 PREX2

4.46e-0322852PS50186
DomainDEP

RGS9 PREX2

4.46e-0322852SM00049
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

DOCK1 DOCK5 MYH11 DST CENPF DOCK8 DOCK9 ANKRD26 AKAP13 DDX39B PREX2 KLC3 HSP90AA1

1.12e-056496813MM15690
PathwayREACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION

DOCK1 DOCK5 KIF27 DOCK8 DOCK9 KLC3

1.97e-05116686MM15715
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

DOCK1 DOCK5 MYH11 DST CENPF DOCK8 DOCK9 ANKRD26 AKAP13 DDX39B PREX2 KLC3 HSP90AA1

3.35e-057206813M41838
PathwayREACTOME_RHO_GTPASE_CYCLE

DOCK1 DOCK5 DST DOCK8 DOCK9 ANKRD26 AKAP13 DDX39B PREX2 HSP90AA1

4.47e-054396810MM15595
PathwayREACTOME_RHO_GTPASE_CYCLE

DOCK1 DOCK5 DST DOCK8 DOCK9 ANKRD26 AKAP13 DDX39B PREX2 HSP90AA1

5.50e-054506810M27078
PathwayREACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION

DOCK1 DOCK5 KIF27 DOCK8 DOCK9 KLC3

1.66e-04170686M941
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

NPHP3 DST PPP5C RABEP1 DOCK9 MORF4L1 SYNE2 ANKRD26 RIOK3 PYGM NEB PHAX HSP90AA1

4.64e-10497891323414517
Pubmed

A human MAP kinase interactome.

DOCK1 MYH11 TOX4 DST NAP1L5 PTPN23 AKAP13 NEB CBLB ZHX1 HSP90AA1 MAP3K4

4.34e-09486891220936779
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK1 DOCK5 DOCK8 DOCK9

3.93e-081489412432077
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

DOCK1 DOCK5 NCOR2 TOX4 KIF27 DOCK8 SEPTIN9 MORF4L1 DDX39B HSP90AA1 RAD50

2.95e-07582891120467437
Pubmed

The interferon-gamma-induced GTPase, mGBP-2, inhibits tumor necrosis factor alpha (TNF-alpha) induction of matrix metalloproteinase-9 (MMP-9) by inhibiting NF-kappaB and Rac protein.

IFNG GBP1 GBP3

5.63e-07789321502320
Pubmed

The interferon-gamma-induced murine guanylate-binding protein-2 inhibits rac activation during cell spreading on fibronectin and after platelet-derived growth factor treatment: role for phosphatidylinositol 3-kinase.

IFNG GBP1 GBP3

5.63e-07789320505078
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

SEL1L NUP50 DST SEPTIN9 MORF4L1 SYNE2 OTUB1 CARS1 QTRT2 PTPN23 AKAP13 RAI14 AIP HSP90AA1 CRTAP

9.92e-071297891533545068
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

DOCK5 SART3 NUP50 CLUAP1 NPHP3 MNS1 NEK5 RABEP1 OTUB1 QTRT2 SPIRE1 RAI14 KLC3 CCDC144A RAD50

1.25e-061321891527173435
Pubmed

Tagging genes with cassette-exchange sites.

NCOR2 SFSWAP SEPTIN9 DOCK9 OTUB1 CARS1 AKAP13 RAI14

2.44e-0633589815741177
Pubmed

Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense.

IFNG GBP1 GBP3

2.63e-061189318025219
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

SART3 NUP50 TRNT1 PPP5C RABEP1 NAP1L5 CARS1 OGFOD1 GBP1 PTPN23 AIP PHAX DDX39B HSP90AA1 CRTAP

4.06e-061455891522863883
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

SART3 NUP50 TOX4 DST RABEP1 SEPTIN9 ANKRD26 PTPN23 RAI14 PHAX HSP90AA1 RAD50

4.67e-06934891233916271
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

SART3 NUP50 DST CENPF SEPTIN9 SPIRE1 RAI14 PHAX DDX39B

6.17e-0650689930890647
Pubmed

Interferon-γ-induced GBP1 is an inhibitor of human papillomavirus 18.

IFNG GBP1

6.48e-06289238622605
Pubmed

Identification of conserved residues required for the binding of a tetratricopeptide repeat domain to heat shock protein 90.

PPP5C HSP90AA1

6.48e-06289210400612
Pubmed

Transient kinetic investigation of GTP hydrolysis catalyzed by interferon-gamma-induced hGBP1 (human guanylate binding protein 1).

IFNG GBP1

6.48e-06289216873363
Pubmed

Overproduction of IFNγ by Cbl-b-Deficient CD8+ T Cells Provides Resistance against Regulatory T Cells and Induces Potent Antitumor Immunity.

IFNG CBLB

6.48e-06289235181779
Pubmed

Two distinct regions of the immunophilin-like protein XAP2 regulate dioxin receptor function and interaction with hsp90.

AIP HSP90AA1

6.48e-06289211805120
Pubmed

The interferon-inducible GBP1 gene: structure and mapping to human chromosome 1.

GBP1 GBP3

6.48e-0628927518790
Pubmed

Aberrant expression of IFN-γ in Th2 cells from Th2 LCR-deficient mice.

IFNG RAD50

6.48e-06289222771806
Pubmed

IFN-γ-response mediator GBP-1 represses human cell proliferation by inhibiting the Hippo signaling transcription factor TEAD.

IFNG GBP1

6.48e-06289230120107
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

SART3 PALS1 KRI1 RAI14 DDX39B HSP90AA1 RAD50

6.93e-0627489734244482
Pubmed

Differential impact of tetratricopeptide repeat proteins on the steroid hormone receptors.

PPP5C AIP HSP90AA1

7.21e-061589320661446
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NCOR2 TOX4 DST CENPF RABEP1 ATF7IP2 RAI14 RAD50

1.23e-0541889834709266
Pubmed

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.

NCOR2 MYH11 CENPF SEPTIN9 RAI14

1.36e-0511889530979931
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

NUP50 NCOR2 TOX4 PPP5C SYNE2 KRI1 PTPN23 RAI14 LTBP1 AIP SLC39A10 HSP90AA1

1.49e-051049891227880917
Pubmed

A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection.

IFNG GBP1 GBP3

1.52e-051989321551061
Pubmed

QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function.

DST RAI14 TNNT2

1.79e-052089333397958
Pubmed

A human apolipoprotein L with detergent-like activity kills intracellular pathogens.

IFNG GBP1

1.94e-05389234437126
Pubmed

GTPase properties of the interferon-induced human guanylate-binding protein 2.

GBP1 GBP3

1.94e-0538928706832
Pubmed

Human protein phosphatase 5 dissociates from heat-shock proteins and is proteolytically activated in response to arachidonic acid and the microtubule-depolymerizing drug nocodazole.

PPP5C HSP90AA1

1.94e-05389215383005
Pubmed

Guanylate binding proteins contained in the murine chromosome 3 are important to control mycobacterial infection.

GBP1 GBP3

1.94e-05389232620042
Pubmed

[Guanylate-binding protein 2 regulates the maturation of mouse dendritic cells induced by β-glucan].

GBP1 GBP3

1.94e-05389229089068
Pubmed

Characterization of the Ah receptor-associated protein, ARA9.

AIP HSP90AA1

1.94e-0538929837941
Pubmed

Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP.

GBP1 GBP3

1.94e-0538921715024
Pubmed

Two families of GTPases dominate the complex cellular response to IFN-gamma.

GBP1 GBP3

1.94e-0538929862701
Pubmed

The interferon (IFN)-induced GTPase, mGBP-2. Role in IFN-gamma-induced murine fibroblast proliferation.

GBP1 GBP3

1.94e-05389211726669
Pubmed

GBP2 inhibits pathological angiogenesis in the retina via the AKT/mTOR/VEGFA axis.

GBP1 GBP3

1.94e-05389238636926
Pubmed

Inhibition of VSV and EMCV replication by the interferon-induced GTPase, mGBP-2: differential requirement for wild-type GTP binding domain.

GBP1 GBP3

1.94e-05389215717119
Pubmed

Interferon gamma repression of collagen (COL1A2) transcription is mediated by the RFX5 complex.

IFNG RFX5

1.94e-05389212968017
Pubmed

Subtyping of microsatellite stability colorectal cancer reveals guanylate binding protein 2 (GBP2) as a potential immunotherapeutic target.

GBP1 GBP3

1.94e-05389235383115
Pubmed

Role of GTP binding, isoprenylation, and the C-terminal α-helices in the inhibition of cell spreading by the interferon-induced GTPase, mouse guanylate-binding protein-2.

GBP1 GBP3

1.94e-05389220950129
Pubmed

Molecular recognition via coupled folding and binding in a TPR domain.

PPP5C HSP90AA1

1.94e-05389215713458
Pubmed

Guanylate binding proteins facilitate caspase-11-dependent pyroptosis in response to type 3 secretion system-negative Pseudomonas aeruginosa.

GBP1 GBP3

1.94e-05389230062052
Pubmed

Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.

GBP1 GBP3

1.94e-05389226416908
Pubmed

Guanylate-binding protein 2 orchestrates innate immune responses against murine norovirus and is antagonized by the viral protein NS7.

GBP1 GBP3

1.94e-05389232354743
Pubmed

Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication.

GBP1 GBP3

1.94e-05389223248289
Pubmed

Conformational diversity in the TPR domain-mediated interaction of protein phosphatase 5 with Hsp90.

PPP5C HSP90AA1

1.94e-05389216531226
Pubmed

Interchromosomal associations between alternatively expressed loci.

IFNG RAD50

1.94e-05389215880101
Pubmed

Domain motions, dimerization, and membrane interactions of the murine guanylate binding protein 2.

GBP1 GBP3

1.94e-05389236639389
Pubmed

Subunit composition of the heteromeric cytosolic aryl hydrocarbon receptor complex.

AIP HSP90AA1

1.94e-0538927961671
Pubmed

The interferon-induced GTPase, mGBP-2, confers resistance to paclitaxel-induced cytotoxicity without inhibiting multinucleation.

GBP1 GBP3

1.94e-05389216914101
Pubmed

The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii.

GBP1 GBP3

1.94e-05389222730319
Pubmed

Coordinated regulation of serum- and glucocorticoid-inducible kinase 3 by a C-terminal hydrophobic motif and Hsp90-Cdc37 chaperone complex.

HSP90AA1 SGK3

1.94e-05389224379398
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

SART3 SFSWAP SERPINB4 RABEP1 MORF4L1 NAP1L5 SPIRE1 RIOK3 PYGM AKAP13 RAI14 KLC3 RAD50

2.31e-051284891317353931
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

DST FAT3 KRI1 RAI14 NEB RAD50

3.17e-0523489636243803
Pubmed

The immunophilin-like protein XAP2 regulates ubiquitination and subcellular localization of the dioxin receptor.

AIP HSP90AA1

3.87e-05489211013261
Pubmed

DOCK5 and DOCK1 regulate Caco-2 intestinal epithelial cell spreading and migration on collagen IV.

DOCK1 DOCK5

3.87e-05489219004829
Pubmed

Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo.

AIP HSP90AA1

3.87e-0548929111057
Pubmed

Phosphatidic acid-dependent recruitment and function of the Rac activator DOCK1 during dorsal ruffle formation.

DOCK1 DOCK5

3.87e-05489223362269
Pubmed

cDNA for the beta 1 subunit of guanyl nucleotide-binding regulatory proteins from mouse adrenal glands.

GBP1 GBP3

3.87e-0548928917111
Pubmed

The Furin Protease Dependence and Antiviral GBP2 Sensitivity of Murine Leukemia Virus Infection Are Determined by the Amino Acid Sequence at the Envelope Glycoprotein Cleavage Site.

GBP1 GBP3

3.87e-05489239337476
Pubmed

Opposing effects of pro- and anti-inflammatory cytokine gene polymorphisms on the risk for breast cancer in western Indian women: a pilot study.

IFNG LTBP1

3.87e-05489224164868
Pubmed

Interferon regulatory factor 1 is required for mouse Gbp gene activation by gamma interferon.

GBP1 GBP3

3.87e-0548927823961
Pubmed

Dnmt1/Tet2-mediated changes in Cmip methylation regulate the development of nonalcoholic fatty liver disease by controlling the Gbp2-Pparγ-CD36 axis.

GBP1 GBP3

3.87e-05489236609599
Pubmed

Evidence that peroxisome proliferator-activated receptor alpha is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2.

AIP HSP90AA1

3.87e-05489212482853
Pubmed

Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin.

PPP5C HSP90AA1

3.87e-0548929195923
Pubmed

HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells.

IFNG RFX5

3.87e-05489219041327
Pubmed

Genomic organization and chromosomal localization of a new member of the murine interferon-induced guanylate-binding protein family.

GBP1 GBP3

3.87e-05489210386861
Pubmed

Helicobacter pylori-induced matrix metallopeptidase-10 promotes gastric bacterial colonization and gastritis.

IFNG MMP10

3.87e-05489230949574
Pubmed

The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo.

DOCK1 DOCK5

3.87e-05489218820033
Pubmed

Guanylate-binding protein-5 is involved in inflammasome activation by bacterial DNA but only the cooperation of multiple GBPs accounts for control of Brucella abortus infection.

GBP1 GBP3

3.87e-05489238404575
Pubmed

Regulation of p21(WAF1/CIP1) stability by WISp39, a Hsp90 binding TPR protein.

PPP5C HSP90AA1

3.87e-05489215664193
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

SEL1L SART3 NUP50 PPP5C NAP1L5 OTUB1 KRI1 QTRT2 PTPN23 AIP RAD50

3.92e-05974891128675297
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SART3 NCOR2 DST RASA2 SERPINB4 SEPTIN9 PTPN23 RIOK3 AKAP13 RAI14 DDX39B HSP90AA1 RAD50

3.97e-051353891329467282
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

SART3 DST CENPF SEPTIN9 SYNE2 CARS1 PTPN23 RAD50

4.28e-0549889836634849
Pubmed

Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.

IFNG GBP1 GBP3

5.64e-052989333278357
Pubmed

The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo.

DOCK1 DOCK5

6.44e-05589224365888
Pubmed

Murine GBP-2: a new IFN-gamma-induced member of the GBP family of GTPases isolated from macrophages.

GBP1 GBP3

6.44e-0558929858320
Pubmed

Dynamic nucleotide-dependent interactions of cysteine- and histidine-rich domain (CHORD)-containing Hsp90 cochaperones Chp-1 and melusin with cochaperones PP5 and Sgt1.

PPP5C HSP90AA1

6.44e-05589223184943
Pubmed

TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2.

GBP1 GBP3

6.44e-05589230858199
Pubmed

Murine GBP-5, a new member of the murine guanylate-binding protein family, is coordinately regulated with other GBPs in vivo and in vitro.

GBP1 GBP3

6.44e-05589212396730
Pubmed

Unique features of different members of the human guanylate-binding protein family.

GBP1 GBP3

6.44e-05589217266443
Pubmed

Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.

GBP1 GBP3

6.44e-05589221151871
Pubmed

Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection.

GBP1 GBP3

6.44e-05589231964735
Pubmed

Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent.

PPP5C HSP90AA1

6.44e-05589221235734
Pubmed

A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

AIP HSP90AA1

6.44e-0558929083006
Pubmed

A molecular signature for IL-10-producing Th1 cells in protozoan parasitic diseases.

IFNG PBX1

6.44e-05589237917177
Pubmed

Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90.

PPP5C HSP90AA1

6.44e-05589230699359
Pubmed

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.

SART3 NUP50 DST PPP5C KRI1 STAMBPL1 AIP HSP90AA1

8.23e-0554789837267103
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

SART3 NUP50 TOX4 KRI1 PHAX DDX39B

9.09e-0528389630585729
Pubmed

Scanning the human proteome for calmodulin-binding proteins.

DST MORF4L1 SYNE2 NEB

9.43e-059289415840729
Pubmed

The role of the e3 ligase cbl-B in murine dendritic cells.

LY75 CBLB

9.65e-05689223762309
Pubmed

Regulation of Nod1 by Hsp90 chaperone complex.

PPP5C HSP90AA1

9.65e-05689216083881
Pubmed

GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells.

IFNG MAP3K4

9.65e-05689215044949
Pubmed

Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy.

GBP1 GBP3

9.65e-05689221757726
Pubmed

Mixed Hsp90-cochaperone complexes are important for the progression of the reaction cycle.

AIP HSP90AA1

9.65e-05689221170051
Pubmed

Single-Cell RNA-Seq of the Developing Cardiac Outflow Tract Reveals Convergent Development of the Vascular Smooth Muscle Cells.

MYH11 TNNT2

9.65e-05689231365875
Pubmed

Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-gamma-inducible gbp2 gene.

GBP1 GBP3

9.65e-05689217293456
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DOCK1 DOCK5 NCOR2 TRNT1 RASA2 RABEP1 SEPTIN9 SPIRE1 ASTN2 AKAP13 RAI14 MME PBX1

1.05e-041489891328611215
CoexpressionGSE18893_TCONV_VS_TREG_2H_CULTURE_DN

SEL1L IFNG MNS1 SYNE2 NEB RFX5 ZHX1 CRTAP

4.16e-07200898M7293
CoexpressionCHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN

DOCK5 NUP50 DST ERAP2 GBP1 GBP3 RIOK3 STAMBPL1 MME ATP10D

3.50e-064578910M14507
CoexpressionCUI_TCF21_TARGETS_2_DN

DOCK5 PALS1 DST RASA2 SPIRE1 RIOK3 MME CBLB ZHX1 PREX2 HSP90AA1 TTLL7 SGK3

6.09e-068548913M1533
CoexpressionCUI_TCF21_TARGETS_2_DN

DOCK5 PALS1 DST RASA2 SPIRE1 RIOK3 MME CBLB ZHX1 PREX2 HSP90AA1 TTLL7 SGK3

9.25e-068888913MM1018
CoexpressionSCHLOSSER_SERUM_RESPONSE_AUGMENTED_BY_MYC

NUP50 NCOR2 PPP5C OTUB1 AIP

3.12e-05106895M15801
CoexpressionGSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_DN

CLUAP1 MYH11 NAP1L5 OGFOD1 LY75 RAD50

5.95e-05198896M3352
CoexpressionGSE11961_MEMORY_BCELL_DAY40_VS_GERMINAL_CENTER_BCELL_DAY40_UP

NUP50 FAT3 FYCO1 RGS9 LTBP1 KLC3

5.95e-05198896M9386
CoexpressionGSE3982_NEUTROPHIL_VS_TH2_DN

DST CENPF OGFOD1 STAMBPL1 DDX39B MAP3K4

5.95e-05198896M5535
CoexpressionGSE32034_LY6C_HIGH_VS_LOW_MONOCYTE_UP

IFNG DOCK5 CENPF MMP10 CRTAP SGK3

6.29e-05200896M9053
CoexpressionGSE21380_NON_TFH_VS_TFH_CD4_TCELL_DN

RASA2 DOCK8 MORF4L1 FYCO1 PBX1 ATP10D

6.29e-05200896M7502
CoexpressionTRAVAGLINI_LUNG_CILIATED_CELL

CCDC170 CLUAP1 DNAH12 KIF27 MNS1 NEK5 SYNE2 CARS1 ANKRD26 GBP1 GBP3 HSP90AA1 TTLL7

7.97e-0510938913M41649
CoexpressionLAKE_ADULT_KIDNEY_C2_PODOCYTES

DOCK5 PALS1 DST RAI14 MME CBLB

8.67e-05212896M39221
CoexpressionZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF

DOCK5 NPHP3 DST SERPINB4 GBP1 GBP3 AKAP13 STAMBPL1 CBLB

1.06e-04550899M2611
CoexpressionLAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2

SYNE2 ANKRD26 ASTN2 AKAP13 MME PBX1

1.09e-04221896M39222
CoexpressionAtlasMyeloid Cells, DC.IIhilang+103-11b+.SLN, MHCIIhi CD11c+ Langerin+ CD103- CD11b+, Lymph Node, avg-3

DOCK1 NDNF PALS1 RASA2 ATF7IP2 GBP1 SPIRE1 PBX1 LY75 CBLB

7.79e-064118810GSM538271_500
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_500

SEL1L DOCK1 DOCK8 AKAP13 MME INO80 TNNT2

2.04e-05201887gudmap_developingKidney_e15.5_500_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#3_top-relative-expression-ranked_100

MYH11 GBP1 TNNT2

2.42e-0514883gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_100_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#2_top-relative-expression-ranked_100

MYH11 GBP1 TNNT2

3.02e-0515883DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k2_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#1_top-relative-expression-ranked_100

MYH11 GBP1 TNNT2

6.35e-0519883gudmap_developingLowerUrinaryTract_e14.5_ bladder_100_k1
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

SART3 NDNF PALS1 MNS1 CENPF RABEP1 ANKRD26 SPIRE1 PREX2 MAP3K4

7.02e-055328810Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

PALS1 DST MNS1 CENPF RABEP1 FAT3 SYNE2 ANKRD26 SPIRE1 AKAP13 NEB

8.10e-056548811Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#4_top-relative-expression-ranked_200

MYH11 GBP1 TNNT2

1.87e-0427883gudmap_developingLowerUrinaryTract_P1_ureter_200_k4
CoexpressionAtlasMyeloid Cells, DC.IIhilang-103-11blo.SLN, MHCIIhi CD11c+ Langerin- CD103- CD11b-, Lymph Node, avg-3

DOCK1 NDNF PALS1 RASA2 GBP1 SPIRE1 LY75 CBLB

2.01e-04386888GSM538277_500
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_top-relative-expression-ranked_500

MYH11 DST DOCK8 NAP1L5 GBP1 CASQ1 NEB TNNT2

2.08e-04388888gudmap_developingLowerUrinaryTract_P1_bladder_500_J
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#3_top-relative-expression-ranked_200

MYH11 GBP1 TNNT2

2.32e-0429883gudmap_developingLowerUrinaryTract_e14.5_ bladder_200_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#2_top-relative-expression-ranked_200

MYH11 GBP1 TNNT2

2.58e-0430883gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_200_k2
CoexpressionAtlasMyeloid Cells, DC.IIhilang-103-11b+.SLN, MHCIIhi CD11c+ Langerin- CD103- CD11b+, Lymph Node, avg-3

DOCK1 NDNF PALS1 RASA2 GBP1 SPIRE1 RAI14 LY75

3.07e-04411888GSM538274_500
CoexpressionAtlasDevelopingLowerUrinaryTract_adult_bladder_emap-29457_top-relative-expression-ranked_100

MYH11 GBP1 TNNT2 TTLL7

3.26e-0479884gudmap_developingLowerUrinaryTract_adult_bladder_100
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#2_top-relative-expression-ranked_200

MYH11 CASQ1 TNNT2

3.43e-0433883gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_200_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#3_top-relative-expression-ranked_200

MYH11 GBP1 TNNT2

3.43e-0433883DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k3_200
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 DST MME TNNT2 CBLB

7.34e-081798977394e77e665bf16d3733df91bb12907be460ab44
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 DST MME TNNT2 CBLB

7.92e-081818975bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 DST MME TNNT2 CBLB

7.92e-081818978e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 DST MME TNNT2 CBLB

9.19e-081858979197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 DST MME TNNT2 CBLB

9.19e-08185897ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 DST MME TNNT2 CBLB

9.19e-08185897b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH12 KIF27 MNS1 NEK5 SYNE2 ANKRD26 LRRC9

1.41e-0719789774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC170 NEK5 DOCK9 GBP3 MME C8A

1.08e-0616789640d102e01ccbc7262d00fafd59ca5234909009cb
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF DST MME TNNT2 CBLB

1.11e-06168896e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 MME TNNT2 CBLB

1.51e-061778964d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 MME TNNT2 CBLB

1.56e-06178896edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 MME TNNT2 CBLB

1.83e-061838963c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 MME TNNT2 CBLB

1.83e-06183896612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 MME TNNT2 CBLB

1.83e-06183896eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 MME TNNT2 CBLB

1.83e-061838969c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 MME TNNT2 CBLB

1.89e-061848967294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

MYH11 DST LTBP1 STAMBPL1 PBX1 TTLL7

2.08e-06187896464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 DST MME TNNT2

2.08e-0618789624c2a3962da364e46e98abeab5f8234376fa26bb
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

CCDC170 DNAH12 KIF27 MNS1 NEK5 HSP90AA1

2.14e-061888968f30535a32968a81a304315a49c0d90a77d36948
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

FAT3 PYGM MME PBX1 CBLB PREX2

2.28e-061908961196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCellmoderate-Epithelial-Ciliated-diff|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC170 CLUAP1 DNAH12 MNS1 CARS1 HSP90AA1

2.35e-061918966cdc6a0c0a1ce5a1ef550832319847f62e718975
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 DST MME TNNT2

2.42e-06192896ef0aba777072429a6ab7dcfcc305673975946580
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 DST MME TNNT2

2.49e-061938963eaa0461618582a1754400624350d269d24e750a
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYH11 FAT3 LTBP1 STAMBPL1 TNNT2 TTLL7

2.81e-06197896bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCellBronchial_Brush-Epithelial|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC170 CLUAP1 DNAH12 MNS1 NEK5 SYNE2

2.81e-06197896272c7f4e582ef57564450540242b0db766b78328
ToppCell10x5'-blood-Lymphocytic_T_CD8-Tem/emra_CD8|blood / Manually curated celltypes from each tissue

IFNG PATL2 SYNE2 RGS9 CBLB HSP90AA1

2.81e-0619789613e6611cde9364f0c1bf681b0b26c4d2725e5f4a
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

CENPF RABEP1 SYNE2 ANKRD26 PBX1 RAD50

2.89e-0619889676d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

RABEP1 SYNE2 ANKRD26 RAI14 HSP90AA1 RAD50

2.97e-0619989619674e1eaeb51e4196d847cb62aa437c852951d3
ToppCellCiliated_cells-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CCDC170 DNAH12 MNS1 NEK5 TTLL7

1.96e-05164895fd30c55d0d75ef8b9396435d836187168095152b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 MME TNNT2

2.20e-05168895fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF DST MME TNNT2

2.20e-05168895315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell3'_v3-Lung-Lymphocytic_T_CD4/8-lo|Lung / Manually curated celltypes from each tissue

IFNG CENPF SYNE2 STAMBPL1 CBLB

2.40e-05171895dfd4a15ab68ef5a9a1954b1b1540ae04017885a6
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|390C / Donor, Lineage, Cell class and subclass (all cells)

IFNG PATL2 SYNE2 GBP1 RGS9

2.40e-05171895d6d8ea45b443d95f64720c9bc07d324148f5b239
ToppCell390C-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DST SERPINB4 CCDC178 MMP10 TNNT2

2.47e-05172895bb542f6ca4eb8167129bc84ca1160a54fbb68731
ToppCell390C-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DST SERPINB4 CCDC178 MMP10 TNNT2

2.47e-05172895aff37b9689b0d30ee7097d997d9588efc475c8fd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF DST MME TNNT2

2.47e-051728956c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF MME TNNT2 CBLB

2.47e-05172895381ae1c3c07d0a424f43455ec571653b192a946a
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC170 GOT1L1 KIF27 MNS1 NEK5

2.54e-05173895a7cc63bb3ab41feb9e4072700d44dbbbc62c47c6
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYH11 FAT3 LTBP1 STAMBPL1 TTLL7

2.54e-05173895cb6389536195443633adb06e5f1b7483530773d1
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC170 GOT1L1 KIF27 MNS1 NEK5

2.54e-05173895e3e3a67a5a93ef4475224a256d45ae24526383cc
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYH11 LTBP1 PBX1 TNNT2 TTLL7

2.54e-051738955416b092321c7d9b63f0418c60f2402a138355bf
ToppCellCOVID-19_Severe-CD4+_CTL|COVID-19_Severe / disease group, cell group and cell class

IFNG PATL2 SYNE2 RGS9 CBLB

2.83e-0517789534e9455790bae905dd91923792f4109d18b7686e
ToppCellIIH-CD8-antiviral_CD4|IIH / Condition, Cell_class and T cell subcluster

PALS1 FYCO1 CBLB RFX5 TTLL7

2.83e-05177895fe73608c40701eca88b260aeb5c0640d7bee72ba
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE2 GBP3 PREX2 HSP90AA1 TTLL7

2.91e-0517889501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellControl-Stromal-SMC|Control / Disease state, Lineage and Cell class

MYH11 LTBP1 STAMBPL1 PBX1 TNNT2

2.99e-051798951378051bc62009eec2dbecf3d5d89baedbeb84eb
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

IFNG PATL2 CENPF RGS9 CBLB

3.07e-05180895f24d4cbba4cb50fce3b3d9c4629aa856d9b05358
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH12 MNS1 NEK5 TTLL7

3.07e-0518089592fb01b91261b3103454924cde56add337b41844
ToppCell3'_v3-bone_marrow-Mast|bone_marrow / Manually curated celltypes from each tissue

MYH11 LTBP1 PBX1 ATP10D TTLL7

3.07e-05180895b37ee81b792213d6595b4ec65d04bc35d83321c7
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

MYH11 FAT3 LTBP1 STAMBPL1 TTLL7

3.07e-05180895d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell10x5'-bone_marrow-Mast-Mast_cell_lympho|bone_marrow / Manually curated celltypes from each tissue

CLUAP1 MYH11 KIF27 ATP10D TTLL7

3.15e-0518189556fa77ae31f3b7de6e441a439c33a11353b6573a
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LTBP1 MME PBX1 PREX2 RAD50

3.23e-0518289519c5e3a9d9b3728303b682102e276adfe93aa759
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

CCDC170 DNAH12 MNS1 NEK5 LRRC9

3.23e-05182895e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

DOCK5 NDNF MME TNNT2 CBLB

3.32e-05183895fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

DST ERAP2 SYNE2 GBP1 GBP3

3.32e-051838958f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF MME TNNT2 CBLB

3.32e-05183895848fc6dd129150897ee339343e83c645b6e779eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 NDNF PALS1 TNNT2 CBLB

3.32e-051838957c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCellControl-Stromal-SMC|World / Disease state, Lineage and Cell class

MYH11 LTBP1 STAMBPL1 PBX1 TNNT2

3.40e-0518489588b1a4c9a96a99fc3a39f7a2c3d0838739606f3e
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

SEL1L IFNG DOCK8 CBLB MAP3K4

3.49e-05185895a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellsaliva-Severe-critical_progression_d28-40|saliva / Compartment, severity and other cell annotations on 10x 3' data (130k)

PALS1 TOX4 RASA2 SYNE2 GBP1

3.59e-051868950095560ca776b01aa473ad4d6015ed78fc93ff51
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

SEL1L IFNG DOCK8 CBLB MAP3K4

3.59e-051868958571956890fc9894d766ba294a28e376b4aba428
ToppCelltumor_Lung-Epithelial_cells-tS3|Epithelial_cells / Location, Cell class and cell subclass

CCDC170 DNAH12 MNS1 NEK5 TTLL7

3.68e-051878953cea677279e71fdb9879530dea10a5e6393beacd
ToppCellP15-Epithelial-airway_epithelial_cell-club_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CCDC170 DNAH12 KIF27 MNS1 NEK5

3.68e-05187895a70aaae32426e9ddb1cbfbd0e0db24ccc96b9f40
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DST SEPTIN9 SPIRE1 ASTN2 CCDC178

3.68e-0518789577886f99c229610abd28c4c370d2c7d1536c9782
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMK+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IFNG PATL2 SYNE2 CBLB HSP90AA1

3.77e-051888952513ca0efa73c09a3406b99e2876982d78b173d7
ToppCellP15-Epithelial-airway_epithelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CCDC170 DNAH12 KIF27 MNS1 NEK5

3.77e-05188895e3e71c0f2e374330620cb4d27638953ffa9f5298
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC170 DNAH12 KIF27 MNS1 NEK5

3.87e-05189895b55de812043b670cbde810d7d42f45909b6d66ef
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH12 KIF27 MNS1 NEK5 HSP90AA1

3.87e-05189895fa1ff8b7fa53f3148d9117d6e598097f03af5eb2
ToppCellPND01-Epithelial-Epithelial_Airway|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC170 DNAH12 KIF27 MNS1 NEK5

3.87e-0518989538cde34295566a4ecaf7d0a81c5a192cf17d0459
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH12 KIF27 MNS1 NEK5 HSP90AA1

3.87e-05189895565063f9e3dd79164321f8a394bd12c176baf202
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH12 KIF27 MNS1 NEK5 HSP90AA1

3.87e-05189895497be236848ebf5ad75d1f0c71e6261f5d3521da
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC170 DNAH12 KIF27 MNS1 NEK5

3.87e-051898954e83e49d1265ffe507fdb72924c77c4d1c73f0bd
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFNG PATL2 RASA2 SYNE2 CBLB

3.97e-05190895d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC170 DNAH12 KIF27 MNS1 NEK5

3.97e-05190895088e3f39a1e5e11354d6e7458e8e6a39f14936b3
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC170 DNAH12 KIF27 MNS1 NEK5

3.97e-0519089535248a8be476ea8d06d67c3d98a25be1f7c150b7
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

NDNF DST FAT3 GBP1 CBLB

3.97e-0519089562a3ec1ae0829602b0569cc051210551644f1d46
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD8-Tem/emra_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

IFNG PATL2 SYNE2 RGS9 CBLB

3.97e-0519089566d29f53f129fc18771f6214316a913eeaccd55e
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC170 DNAH12 KIF27 MNS1 NEK5

3.97e-051908955f5206f9e725070d865f4c891ff08bb750e58582
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH12 KIF27 MNS1 NEK5 HSP90AA1

4.07e-05191895acd844b477a069b2dcf07b2998e1b5c87dc0eb94
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 CLUAP1 DNAH12 MNS1 CENPF

4.07e-05191895683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC170 DNAH12 KIF27 MNS1 NEK5

4.07e-05191895bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC170 DNAH12 KIF27 MNS1 NEK5

4.07e-051918956880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCellMyeloid-Myeloid-B_(Activated_Macrophage)|Myeloid / shred on cell class and cell subclass (v4)

DST SEPTIN9 LY75 HSP90AA1 FBXL5

4.07e-051918957bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 LTBP1 STAMBPL1 PBX1 CBLB

4.07e-051918951caf726bd07fdca389e678fc16304a6ef1790423
ToppCellmoderate-Epithelial-Ciliated-diff|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC170 DNAH12 MNS1 CARS1 HSP90AA1

4.07e-05191895b1bb27aab6ec651b45d5eea0a6b61a1da0fc6204
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMK+-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

IFNG PATL2 SYNE2 CBLB HSP90AA1

4.07e-051918952ad34ccd55362db04511c90cf264ae5b93b48dde
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 LTBP1 STAMBPL1 PBX1 CBLB

4.07e-051918953d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC170 DNAH12 KIF27 MNS1 NEK5

4.07e-0519189596483adb97c81208aa513782550acd8a08b63866
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 LTBP1 STAMBPL1 PBX1 CBLB

4.17e-051928954022f208eb5db760abd0aac782a25e8ab63efc64
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMK+|normal / PBMC cell types (v2) per disease, treatment status, and sex

IFNG PATL2 SYNE2 CBLB HSP90AA1

4.17e-051928957460ce6e2f91bbf940b684f63231db7501ace09f
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC170 DNAH12 KIF27 MNS1 NEK5

4.17e-05192895b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMK+|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IFNG PATL2 SYNE2 CBLB HSP90AA1

4.17e-0519289571bc03b08cda0382ea45b503d5f4f135ed98cc11
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 LTBP1 STAMBPL1 PBX1 CBLB

4.17e-051928959333aba0d04203ccccad78d82bf6359922f810a7
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FAT3 PYGM MME PBX1 PREX2

4.17e-051928950afb9dbe468e0be442c326e11c5fc0f699b32f23
ToppCellPND03-Epithelial-Epithelial_Airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC170 DNAH12 KIF27 MNS1 NEK5

4.17e-051928952d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCelldroplet-Fat-Mat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH11 DST DOCK9 PREX2 TTLL7

4.27e-0519389554024a373e42e1c0bcc327dc084564b83b63a9d4
ToppCelldroplet-Fat-Mat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH11 DST DOCK9 PREX2 TTLL7

4.27e-0519389581d908594d2983ba7e7c1ec25afdde4315d9690e
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DST FAT3 LTBP1 PBX1 PREX2

4.27e-05193895b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH12 MNS1 NEK5 CARS1

4.38e-051948953cd90d01ed5a5ce65aad8284dab2537ec16e3d7c
ToppCellcritical-Epithelial-Ciliated-diff|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC170 DNAH12 MNS1 CARS1 HSP90AA1

4.38e-05194895176090949b53c043c58df63ad8cf4f486b350bdc
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IFNG DOCK5 PATL2 SYNE2 RGS9

4.38e-0519489524837a27b0041fe8c348225fa8b09b127d743603
Drugtestosterone enanthate

SART3 NDNF CLUAP1 MYH11 TOX4 ERAP2 GBP1 ASTN2 AKAP13 LTBP1 SGK3 RAD50

2.43e-065758912ctd:C004648
DiseaseHyper-Immunoglobulin E Syndrome, Autosomal Recessive

IFNG DOCK8

2.63e-053882C1968689
DiseaseHyper-Immunoglobulin E Syndrome, Autosomal Dominant

IFNG DOCK8

2.63e-053882C2936739
Diseaseglycosyl ceramide (d16:1/24:1, d18:1/22:1) measurement

SYNE2 ATP10D

2.63e-053882EFO_0800530
DiseaseJob Syndrome

IFNG DOCK8

5.26e-054882C3887645
Diseaseforced expiratory volume

NCOR2 CLUAP1 DNAH12 DST SEPTIN9 DOCK9 RIOK3 ASTN2 INO80 HSP90AA1

1.22e-047898810EFO_0004314
Diseaseretinal detachment, retinal break

SFSWAP FAT3 CRTAP

1.57e-0435883EFO_0005773, EFO_0010698
Diseaseglycosyl ceramide (d18:1/20:0, d16:1/22:0) measurement

SYNE2 ATP10D

1.83e-047882EFO_0800551
Diseasetype 1 diabetes mellitus (implicated_via_orthology)

IFNG DOCK8 CBLB

2.17e-0439883DOID:9744 (implicated_via_orthology)
Diseasenemaline myopathy (implicated_via_orthology)

NEB TNNT2

2.43e-048882DOID:3191 (implicated_via_orthology)
Diseasediastolic blood pressure change measurement

TRNT1 PPP5C ERAP2

4.54e-0450883EFO_0006945
Diseasemean platelet volume

DOCK5 MYH11 TOX4 DOCK8 RABEP1 SYNE2 LTBP1 PBX1 LY75 DDX39B

9.18e-0410208810EFO_0004584
Diseaselupus nephritis (is_marker_for)

IFNG OTUB1

1.16e-0317882DOID:0080162 (is_marker_for)
Diseaselevel of Sphingomyelin (d32:1) in blood serum

RABEP1 SYNE2

1.16e-0317882OBA_2045173
DiseaseRenal Insufficiency

IFNG MME

1.16e-0317882C1565489
DiseaseContact Dermatitis

SERPINB4 MMP10 HSP90AA1

1.27e-0371883C0011616
DiseaseContact hypersensitivity

SERPINB4 MMP10 HSP90AA1

1.27e-0371883C0162351
Diseaseaspartate aminotransferase measurement

NCOR2 NPHP3 KIF27 ERAP2 ASTN2 AKAP13 FYCO1 LY75 TTLL7

1.50e-03904889EFO_0004736
DiseaseBRCAX breast cancer

CCDC170 DOCK1

1.61e-0320882EFO_0009443
DiseaseKidney Failure

IFNG MME

1.95e-0322882C0035078
Diseaseneutrophil percentage of leukocytes

ERAP2 DOCK8 SEPTIN9 KRI1 AKAP13 LY75 RAD50

2.33e-03610887EFO_0007990
Diseasemigraine disorder, diastolic blood pressure

NCOR2 ASTN2

2.52e-0325882EFO_0006336, MONDO_0005277
DiseaseAcute kidney injury

GBP1 GBP3

2.52e-0325882HP_0001919
Diseaseneutrophil count

RASA2 ERAP2 DOCK8 RABEP1 SEPTIN9 KRI1 RIOK3 AKAP13 PBX1 LY75 PREX2

2.68e-0313828811EFO_0004833

Protein segments in the cluster

PeptideGeneStartEntry
LNELNKYNEKKFIFT

C8A

276

P07357
GLQQYYVKLKDNEKN

DDX39B

261

Q13838
LKTYKQDDYPNKIFL

GOT1L1

21

Q8NHS2
QSVNYFKDLYAKDKR

AKAP13

2106

Q12802
NELKQRFGEIYEKYK

CCDC144CP

246

Q8IYA2
DFNKTELEKYKQLYL

ANKRD26

1546

Q9UPS8
NKAEEIADKIYNLYN

ASTN2

1196

O75129
EDYRKYKIDKQINNL

ATP10D

141

Q9P241
SILNKYDDNVKAYFK

AIP

256

O00170
IFKDYEKYLANIEQQ

NUP50

186

Q9UKX7
NKEKAFLFEKYQEAQ

RAI14

591

Q9P0K7
NNKENLRYYVDKLFN

RASA2

451

Q15283
IENYIQDGKDDYKKQ

RAD50

961

Q92878
EQEFNQKRAKFKELY

RABEP1

36

Q15276
QDVQKFSDNDKLYLY

RFX5

51

P48382
LEEYEKENYNFLNQK

RGS9

136

O75916
LFEEQLKKYDQLKVY

PTPN23

601

Q9H3S7
LKKYDQLKVYLEQNL

PTPN23

606

Q9H3S7
QNKYSKDKELQQYQY

INO80

171

Q9ULG1
EKLYLYFNKISKIEN

LRRC9

101

Q6ZRR7
KKNVDSILEDYANYK

MORF4L1

226

Q9UBU8
KDLAQQYLEKYYNLE

MMP10

31

P09238
QYLEKYYNLEKDVKQ

MMP10

36

P09238
KYNDLYKFQQSDDLK

OGFOD1

91

Q8N543
NFYFNYKKRQNLDEI

NCOR2

651

Q9Y618
YKKNIGKFQEEANIY

PBX1

291

P40424
IYNYLIFDKPEKNKQ

nan

911

O00370
KKNQIENYKEDKYSE

MAP10

466

Q9P2G4
LKALYNQYLQFKETE

DST

306

Q03001
SYKLEYLLQFDQKEK

FYCO1

46

Q9BQS8
QKLAQLSENEYFKIY

CBLB

96

Q13191
LKEKDNYFNIYDKQL

CCDC178

771

Q5BJE1
DKIQQLEKDLYFYKK

KIF27

1201

Q86VH2
QPKEEKKECYYNLND

LTBP1

1341

Q14766
EYLQRKFEAQQYKLK

NEK5

406

Q6P3R8
YKEKIINENYNPKFF

FAM214A

656

Q32MH5
NKLNNEYLELNYKED

MME

491

P08473
AYQNYIKKNGEEKLL

MME

661

P08473
LKKYYKELQNQLNEI

DNAH12

1131

Q6ZR08
FEQEYLNDLMKKYDK

LY75

536

O60449
YKKEVDDNYNEDQKK

NDNF

481

Q8TB73
LFLKKQEDFEQKYNF

KRI1

286

Q8N9T8
FVQKLQDLKKKYYEE

GBP1

436

P32455
YCLFIQKLQDLEKKY

GBP3

431

Q9H0R5
LKQNKYQQAEELYKE

KLC3

386

Q6P597
KKVLYNANKNDDYDN

PALS1

446

Q8N3R9
YYQKLEKKQADEELL

PATL2

221

C9JE40
YAEDDNIYQQKIKDL

OTUB1

61

Q96FW1
FEINLKEKKYQEDFN

QTRT2

331

Q9H974
YEQLSELLKKQAQFY

DOCK1

1311

Q14185
NVLNFYKEKKREDIY

DOCK5

1226

Q9H7D0
EYQQELKKNYNKLKE

DOCK8

2041

Q8NF50
SYNLNFYKDEKISKE

DOCK9

211

Q9BZ29
YEDLSQKYKAAQEKN

CENPF

1036

P49454
LQFAYYKLNDLKNAA

CRTAP

301

O75718
NYKNVFKKYEVLALL

CASQ1

56

P31415
KELDYEKQQFYNLTV

FAT3

996

Q8TDW7
NELKQRFGEIYEKYK

CCDC144B

296

Q3MJ40
QQEIYSINYELFDKK

ATF7IP2

326

Q5U623
YLKKFSYRNAKNDDL

ERAP2

481

Q6P179
PYVKEAENLKKYFNA

IFNG

26

P01579
YFKLFKNFKDDQSIQ

IFNG

76

P01579
LRDNLNFEKQKYLKF

CCDC170

421

Q8IYT3
NFEKQKYLKFLDQLS

CCDC170

426

Q8IYT3
LKNVKNEYEQLNYAK

FBXL5

96

Q9UKA1
ELAEDKENYKKFYEQ

HSP90AA1

426

P07900
NELKQRFGEIYEKYK

CCDC144A

296

A2RUR9
NKALQQLEKYKPYEE

SART3

286

Q15020
FSKQAAENEKKYYIE

SLC39A10

51

Q9ULF5
YAEFDKLYNTLKKQF

SGK3

51

Q96BR1
DIFYIENQKEYENKK

PHAX

306

Q9H814
LQALQKDYEKYAAKD

MAP3K4

371

Q9Y6R4
AEDKRNKAKAQYYLD

MNS1

176

Q8NEH6
NKAKAQYYLDLEKQL

MNS1

181

Q8NEH6
NAYYEFKKQFFLQKE

SFSWAP

496

Q12872
LFDYFNGYEDLKNKK

TRNT1

166

Q96Q11
KLFEAQEKLYKEYLQ

CARS1

726

P49589
LLKDSENDTYFKKYN

SYNE2

316

Q8WXH0
NYDLALKYFQKAAEQ

SEL1L

466

Q9UBV2
NEKKQYDKAEELYER

NPHP3

1146

Q7Z494
EFQALEKKYNDIYKP

NAP1L5

101

Q96NT1
LKTQANDYFKAKDYE

PPP5C

31

P53041
NDYFKAKDYENAIKF

PPP5C

36

P53041
KFINDQYEKYLQEEV

SEPTIN9

381

Q9UHD8
ELQKQYDTYLEKFQN

CLUAP1

251

Q96AJ1
QQYEEKAAAYDKLEK

MYH11

1406

P35749
LNEFKNRDKYIKDDF

RIOK3

296

O14730
ENKLKFAAYLEREYK

PYGM

541

P11217
VKAELEKYQQYKDIY

SPIRE1

571

Q08AE8
LKNDLLKKYNVEYQE

STAMBPL1

121

Q96FJ0
YNLEAEKFDLQEKFK

TNNT2

251

P45379
EKFDLQEKFKQQKYE

TNNT2

256

P45379
KDYYLKHKFLNEQDL

ZHX1

786

Q9UKY1
KTYQFLQEYLDAIKK

SERPINB4

111

P48594
DFLFNQDNKDKLKEY

STAB2

1796

Q8WWQ8
VKQYNQKLRAFYLDK

PREX2

1441

Q70Z35
KEYLKALAAYKDNQE

TOX4

281

O94842
AEYTQFQNYVKELKK

TTLL7

136

Q6ZT98
NYKKKLQEFSKEEEY

TRIM16L

111

Q309B1
KKAYELQSDNVYKAD

NEB

4101

P20929
QIKYKKNALENYPNF

NEB

4386

P20929