Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN10A CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

3.05e-1526287GO:0005248
GeneOntologyMolecularFunctionsodium channel activity

SCN10A CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

6.06e-1352287GO:0005272
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN10A CACNA1H CACNA1G SLC13A2 SCN4A SCN5A SCN7A TPCN1

6.59e-11171288GO:0015081
GeneOntologyMolecularFunctiontransmembrane transporter activity

SCN10A SLC44A2 CACNA1S CACNA1H CACNA1G SLC43A3 SLC13A2 SLC16A2 SCN4A SLC22A10 SCN5A SCN7A TPCN1

1.63e-0911802813GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SCN10A SLC44A2 CACNA1S CACNA1H CACNA1G SLC43A3 SLC13A2 SLC16A2 SCN4A SLC22A10 SCN5A SCN7A TPCN1

4.78e-0912892813GO:0005215
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SCN10A CACNA1S CACNA1H CACNA1G SLC13A2 SCN4A SCN5A SCN7A TPCN1

8.69e-09465289GO:0046873
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

1.61e-08343288GO:0005261
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SCN10A CACNA1S CACNA1H CACNA1G SLC13A2 SCN4A SCN5A SCN7A TPCN1

1.13e-07627289GO:0022890
GeneOntologyMolecularFunctionmonoatomic ion channel activity

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

1.52e-07459288GO:0005216
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SCN10A CACNA1S CACNA1H CACNA1G SLC13A2 SCN4A SCN5A SCN7A TPCN1

1.85e-07664289GO:0008324
GeneOntologyMolecularFunctionchannel activity

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

4.23e-07525288GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

4.29e-07526288GO:0022803
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SCN10A CACNA1S CACNA1H CACNA1G SLC13A2 SCN4A SCN5A SCN7A TPCN1

5.63e-07758289GO:0015318
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SCN10A CACNA1S CACNA1H CACNA1G SLC13A2 SCN4A SCN5A SCN7A TPCN1

8.22e-07793289GO:0015075
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1S CACNA1H CACNA1G

8.90e-0714283GO:0008331
GeneOntologyMolecularFunctionvoltage-gated channel activity

SCN10A CACNA1S CACNA1H CACNA1G TPCN1

5.21e-06184285GO:0022832
GeneOntologyMolecularFunctionlow voltage-gated calcium channel activity

CACNA1H CACNA1G

5.68e-063282GO:0008332
GeneOntologyMolecularFunctiongated channel activity

SCN10A CACNA1S CACNA1H CACNA1G SCN7A TPCN1

5.78e-06334286GO:0022836
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity involved in cardiac muscle cell action potential

SCN10A SCN5A

2.83e-056282GO:0086006
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1S CACNA1H CACNA1G TPCN1

3.02e-05129284GO:0005262
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1S CACNA1H CACNA1G

3.60e-0546283GO:0005245
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1S CACNA1H CACNA1G TPCN1

5.59e-05151284GO:0015085
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

SCN10A CACNA1S CACNA1H CACNA1G

1.15e-04182284GO:0005244
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC43A3 SLC13A2 SLC16A2 SLC22A10

1.89e-04207284GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC43A3 SLC13A2 SLC16A2 SLC22A10

1.92e-04208284GO:0005342
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLC43A3 SLC16A2 SLC22A10

2.67e-0490283GO:0008028
GeneOntologyMolecularFunctionscaffold protein binding

CACNA1H CACNA1G SCN5A

2.94e-0493283GO:0097110
GeneOntologyMolecularFunctionfatty acid transmembrane transporter activity

SLC43A3 SLC22A10

4.71e-0423282GO:0015245
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC43A3 SLC13A2 SLC16A2 SLC22A10

7.04e-04293284GO:0008514
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC44A2 SLC13A2 SLC16A2 SLC22A10

7.32e-04296284GO:0015291
GeneOntologyMolecularFunctionG protein-coupled receptor activity

QRFPR OR10H5 MCHR1 OR10H2 OR10H1 ADGRL3

1.21e-03884286GO:0004930
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1S CACNA1H CACNA1G

1.23e-03152283GO:0022843
GeneOntologyMolecularFunctiontransmembrane transporter binding

SCN10A SCN5A SCN7A

1.76e-03172283GO:0044325
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

QRFPR OR10H5 MCHR1 OR10H2 OR10H1 ADGRL3 SCN7A

2.16e-031353287GO:0004888
GeneOntologyMolecularFunctionneuropeptide receptor activity

QRFPR MCHR1

2.50e-0353282GO:0008188
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC44A2 SLC13A2 SLC16A2 SLC22A10

4.18e-03477284GO:0022804
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

SLC43A3 SLC22A10

4.69e-0373282GO:0170055
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

QRFPR MCHR1

1.49e-02133282GO:0008528
GeneOntologyMolecularFunctionpeptide receptor activity

QRFPR MCHR1

1.64e-02140282GO:0001653
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SCN10A CACNA1H CACNA1G SLC13A2 SCN4A SCN5A SCN7A TPCN1

2.44e-10208288GO:0035725
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN10A CACNA1H CACNA1G SCN4A SCN5A

1.16e-0936285GO:0086010
GeneOntologyBiologicalProcesssodium ion transport

SCN10A CACNA1H CACNA1G SLC13A2 SCN4A SCN5A SCN7A TPCN1

2.23e-09275288GO:0006814
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN10A CACNA1H CACNA1G SCN4A SCN5A SCN7A

2.48e-0993286GO:0086003
GeneOntologyBiologicalProcessstriated muscle contraction

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A

1.27e-08217287GO:0006941
GeneOntologyBiologicalProcessactin-mediated cell contraction

SCN10A CACNA1H CACNA1G SCN4A SCN5A SCN7A

1.63e-08127286GO:0070252
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN10A CACNA1G SCN4A SCN5A SCN7A

1.94e-0862285GO:0086002
GeneOntologyBiologicalProcessneuronal action potential

SCN10A CACNA1H CACNA1G SCN4A SCN5A

2.10e-0863285GO:0019228
GeneOntologyBiologicalProcessactin filament-based movement

SCN10A CACNA1H CACNA1G SCN4A SCN5A SCN7A

4.97e-08153286GO:0030048
GeneOntologyBiologicalProcesscardiac muscle contraction

SCN10A CACNA1H CACNA1G SCN4A SCN5A SCN7A

8.37e-08167286GO:0060048
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN10A CACNA1G SCN4A SCN5A SCN7A

1.08e-0787285GO:0086001
GeneOntologyBiologicalProcessaction potential

SCN10A CACNA1H CACNA1G SCN4A SCN5A SCN7A

2.50e-07201286GO:0001508
GeneOntologyBiologicalProcessregulation of atrial cardiac muscle cell membrane depolarization

SCN10A CACNA1G SCN5A

2.67e-0710283GO:0060371
GeneOntologyBiologicalProcesstransmission of nerve impulse

SCN10A CACNA1H CACNA1G SCN4A SCN5A

3.84e-07112285GO:0019226
GeneOntologyBiologicalProcessmetal ion transport

SCN10A CACNA1S CACNA1H CACNA1G MCHR1 SLC13A2 SCN4A SCN5A SCN7A TPCN1

4.05e-0710002810GO:0030001
GeneOntologyBiologicalProcessmuscle system process

SCN10A CACNA1S CACNA1H CACNA1G KDM4A SCN4A SCN5A SCN7A

4.53e-07547288GO:0003012
GeneOntologyBiologicalProcessAV node cell to bundle of His cell signaling

SCN10A CACNA1G SCN5A

4.89e-0712283GO:0086027
GeneOntologyBiologicalProcessAV node cell action potential

SCN10A CACNA1G SCN5A

4.89e-0712283GO:0086016
GeneOntologyBiologicalProcessmembrane depolarization

SCN10A CACNA1H CACNA1G SCN4A SCN5A

5.64e-07121285GO:0051899
GeneOntologyBiologicalProcessmuscle contraction

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A

8.15e-07400287GO:0006936
GeneOntologyBiologicalProcessmonoatomic ion transport

SCN10A CACNA1S CACNA1H CACNA1G MCHR1 SLC13A2 SCN4A SLC22A10 SCN5A SCN7A TPCN1

8.22e-0713742811GO:0006811
GeneOntologyBiologicalProcessAV node cell to bundle of His cell communication

SCN10A CACNA1G SCN5A

1.01e-0615283GO:0086067
GeneOntologyBiologicalProcessmonoatomic cation transport

SCN10A CACNA1S CACNA1H CACNA1G MCHR1 SLC13A2 SCN4A SCN5A SCN7A TPCN1

1.54e-0611572810GO:0006812
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SCN10A CACNA1S CACNA1H CACNA1G SLC13A2 SCN4A SCN5A SCN7A TPCN1

2.20e-06922289GO:0098662
GeneOntologyBiologicalProcessheart contraction

SCN10A CACNA1H CACNA1G SCN4A SCN5A SCN7A

2.49e-06298286GO:0060047
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SCN10A CACNA1S CACNA1H CACNA1G SLC13A2 SCN4A SCN5A SCN7A TPCN1

2.62e-06942289GO:0098655
GeneOntologyBiologicalProcessheart process

SCN10A CACNA1H CACNA1G SCN4A SCN5A SCN7A

3.07e-06309286GO:0003015
GeneOntologyBiologicalProcesscirculatory system process

SCN10A POSTN CACNA1H CACNA1G SLC16A2 SCN4A SCN5A SCN7A

4.05e-06733288GO:0003013
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SCN10A CACNA1S CACNA1H CACNA1G SLC13A2 SCN4A SCN5A SCN7A TPCN1

4.91e-061017289GO:0098660
GeneOntologyBiologicalProcessregulation of muscle contraction

SCN10A CACNA1S CACNA1H SCN4A SCN5A

7.01e-06202285GO:0006937
GeneOntologyBiologicalProcessregulation of membrane potential

SCN10A CACNA1H CACNA1G UCN3 SCN4A SCN5A SCN7A

7.46e-06559287GO:0042391
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SCN10A CACNA1S CACNA1H CACNA1G SLC13A2 SCN4A SCN5A SCN7A TPCN1

1.04e-051115289GO:0034220
GeneOntologyBiologicalProcesscell-cell signaling involved in cardiac conduction

SCN10A CACNA1G SCN5A

1.30e-0534283GO:0086019
GeneOntologyBiologicalProcessimport across plasma membrane

CACNA1S CACNA1H CACNA1G SLC16A2 SCN5A

1.32e-05230285GO:0098739
GeneOntologyBiologicalProcessregulation of striated muscle contraction

SCN10A CACNA1H SCN4A SCN5A

1.47e-05111284GO:0006942
GeneOntologyBiologicalProcessmembrane depolarization during SA node cell action potential

CACNA1G SCN5A

1.77e-055282GO:0086046
GeneOntologyBiologicalProcessblood circulation

SCN10A POSTN CACNA1H CACNA1G SCN4A SCN5A SCN7A

1.95e-05648287GO:0008015
GeneOntologyBiologicalProcessmembrane depolarization during AV node cell action potential

CACNA1G SCN5A

2.66e-056282GO:0086045
GeneOntologyBiologicalProcessbundle of His cell action potential

SCN10A SCN5A

3.72e-057282GO:0086043
GeneOntologyBiologicalProcessbundle of His cell to Purkinje myocyte signaling

SCN10A SCN5A

3.72e-057282GO:0086028
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

CACNA1S CACNA1H CACNA1G

3.72e-0548283GO:0098703
GeneOntologyBiologicalProcesscalcium ion import into cytosol

CACNA1S CACNA1H CACNA1G

3.72e-0548283GO:1902656
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

CACNA1S CACNA1H CACNA1G SCN5A

3.88e-05142284GO:0098659
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

CACNA1S CACNA1H CACNA1G SCN5A

3.88e-05142284GO:0099587
GeneOntologyBiologicalProcessregulation of muscle system process

SCN10A CACNA1S CACNA1H SCN4A SCN5A

6.11e-05317285GO:0090257
GeneOntologyBiologicalProcesscell communication involved in cardiac conduction

SCN10A CACNA1G SCN5A

6.92e-0559283GO:0086065
GeneOntologyBiologicalProcessregulation of membrane depolarization

SCN10A CACNA1G SCN5A

7.65e-0561283GO:0003254
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell signaling

CACNA1G SCN5A

7.94e-0510282GO:0086018
GeneOntologyBiologicalProcessSA node cell action potential

CACNA1G SCN5A

7.94e-0510282GO:0086015
GeneOntologyBiologicalProcesscholine transport

SLC44A2 SCN4A

7.94e-0510282GO:0015871
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell communication

CACNA1G SCN5A

9.70e-0511282GO:0086070
GeneOntologyBiologicalProcessbundle of His cell to Purkinje myocyte communication

SCN10A SCN5A

1.85e-0415282GO:0086069
GeneOntologyBiologicalProcessregulation of cardiac muscle contraction

SCN10A CACNA1H SCN5A

2.35e-0489283GO:0055117
GeneOntologyBiologicalProcesscalcium ion import

CACNA1S CACNA1H CACNA1G

3.13e-0498283GO:0070509
GeneOntologyBiologicalProcesscardiac conduction

SCN10A CACNA1G SCN5A

3.32e-04100283GO:0061337
GeneOntologyBiologicalProcesspositive regulation of calcium ion-dependent exocytosis

CACNA1H CACNA1G

3.33e-0420282GO:0045956
GeneOntologyBiologicalProcessregulation of heart contraction

SCN10A CACNA1H CACNA1G SCN5A

3.38e-04249284GO:0008016
GeneOntologyBiologicalProcessregulation of system process

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A

3.83e-04734286GO:0044057
GeneOntologyBiologicalProcessmembrane depolarization during cardiac muscle cell action potential

CACNA1G SCN5A

4.42e-0423282GO:0086012
GeneOntologyBiologicalProcesscalcium ion transport

CACNA1S CACNA1H CACNA1G MCHR1 TPCN1

5.51e-04509285GO:0006816
GeneOntologyBiologicalProcessorganic anion transport

SLC43A3 SLC13A2 SLC16A2 OC90 SLC22A10

5.81e-04515285GO:0015711
GeneOntologyBiologicalProcessneuropeptide signaling pathway

QRFPR UCN3 MCHR1

6.22e-04124283GO:0007218
GeneOntologyBiologicalProcessregulation of heart rate

SCN10A CACNA1G SCN5A

6.98e-04129283GO:0002027
GeneOntologyBiologicalProcessregulation of blood circulation

SCN10A CACNA1H CACNA1G SCN5A

9.30e-04326284GO:1903522
GeneOntologyBiologicalProcessactin filament-based process

SCN10A CACNA1H CACNA1G SCN4A SCN5A SCN7A

1.20e-03912286GO:0030029
GeneOntologyBiologicalProcesscardiac conduction system development

CACNA1G SCN5A

1.34e-0340282GO:0003161
GeneOntologyBiologicalProcessmuscle adaptation

CACNA1S KDM4A SCN5A

1.40e-03164283GO:0043500
GeneOntologyBiologicalProcessregulation of heart rate by cardiac conduction

CACNA1G SCN5A

1.41e-0341282GO:0086091
GeneOntologyBiologicalProcessregulation of cardiac muscle cell contraction

CACNA1H SCN5A

1.55e-0343282GO:0086004
GeneOntologyBiologicalProcessregulation of calcium ion-dependent exocytosis

CACNA1H CACNA1G

1.70e-0345282GO:0017158
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

CACNA1S CACNA1H CACNA1G TPCN1

1.83e-03392284GO:0070588
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

QRFPR UCN3 OR10H5 MCHR1 OR10H2 OR10H1 ADGRL3

2.14e-031395287GO:0007186
GeneOntologyBiologicalProcesscarboxylic acid transport

SLC43A3 SLC13A2 SLC16A2 OC90

2.16e-03410284GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

SLC43A3 SLC13A2 SLC16A2 OC90

2.20e-03412284GO:0015849
GeneOntologyBiologicalProcessregulation of actin filament-based movement

CACNA1H SCN5A

2.35e-0353282GO:1903115
GeneOntologyBiologicalProcessimport into cell

CACNA1S CACNA1H CACNA1G SLC16A2 SCN5A TPCN1

2.76e-031074286GO:0098657
GeneOntologyBiologicalProcessmyoblast fusion

CACNA1S CACNA1H

2.80e-0358282GO:0007520
GeneOntologyBiologicalProcessmonocarboxylic acid transport

SLC43A3 SLC16A2 OC90

2.94e-03213283GO:0015718
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

CACNA1S CACNA1H CACNA1G

3.10e-03217283GO:0097553
GeneOntologyBiologicalProcesspositive regulation of regulated secretory pathway

CACNA1H CACNA1G

3.61e-0366282GO:1903307
GeneOntologyBiologicalProcessstriated muscle adaptation

CACNA1S KDM4A

4.40e-0373282GO:0014888
GeneOntologyBiologicalProcessphosphatidylcholine metabolic process

SLC44A2 OC90

5.01e-0378282GO:0046470
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN10A CACNA1H CACNA1G SCN4A SCN5A SCN7A

3.99e-1417286GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN10A CACNA1H CACNA1G SCN4A SCN5A SCN7A

1.51e-1229286GO:0034706
GeneOntologyCellularComponentcation channel complex

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A

2.01e-08235287GO:0034703
GeneOntologyCellularComponentmonoatomic ion channel complex

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

2.41e-08378288GO:0034702
GeneOntologyCellularComponenttransmembrane transporter complex

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

2.91e-07523288GO:1902495
GeneOntologyCellularComponenttransporter complex

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

4.26e-07550288GO:1990351
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1S CACNA1H CACNA1G

3.14e-0546283GO:0005891
GeneOntologyCellularComponentplasma membrane protein complex

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A

6.08e-05785287GO:0098797
GeneOntologyCellularComponentcalcium channel complex

CACNA1S CACNA1H CACNA1G

1.26e-0473283GO:0034704
GeneOntologyCellularComponentmembrane protein complex

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

5.80e-041498288GO:0098796
GeneOntologyCellularComponentsarcolemma

CACNA1S CACNA1H SCN5A

2.05e-03190283GO:0042383
GeneOntologyCellularComponentnon-motile cilium

QRFPR MCHR1 RDH11

2.24e-03196283GO:0097730
HumanPhenoHypokalemia

SCN10A CACNA1S SCN4A SCN5A

3.58e-067984HP:0002900
HumanPhenoReduced systolic function

CACNA1S SCN4A SCN5A

4.44e-062383HP:0006673
HumanPhenoMalignant hyperthermia

CACNA1S SCN4A SCN5A

6.50e-062683HP:0002047
HumanPhenoAbnormal blood potassium concentration

SCN10A CACNA1S SCN4A SCN5A

1.50e-0511384HP:0011042
HumanPhenoEpisodic hypokalemia

CACNA1S SCN4A

3.23e-05682HP:0012726
HumanPhenoEpisodic flaccid weakness

CACNA1S SCN4A

4.52e-05782HP:0003752
HumanPhenoAbnormal blood monovalent inorganic cation concentration

SCN10A CACNA1S SCN4A SCN5A

5.12e-0515484HP:0010930
HumanPhenoLate-onset proximal muscle weakness

CACNA1S SCN4A

6.02e-05882HP:0003694
HumanPhenoProlonged QT interval

SCN10A CACNA1S SCN5A

6.08e-055483HP:0001657
HumanPhenoRespiratory paralysis

CACNA1S SCN4A

7.73e-05982HP:0002203
HumanPhenoPostprandial hyperglycemia

CACNA1S SCN4A

7.73e-05982HP:0011998
HumanPhenoPeriodic hypokalemic paresis

CACNA1S SCN4A

7.73e-05982HP:0008153
HumanPhenoAdrenocortical adenoma

CACNA1S SCN4A

7.73e-05982HP:0008256
HumanPhenoImpaired myocardial contractility

CACNA1S SCN4A

9.65e-051082HP:0006670
HumanPhenoApneic episodes in infancy

SCN4A SCN5A

9.65e-051082HP:0005949
HumanPhenoVentricular fibrillation

SCN10A CACNA1S SCN5A

9.66e-056383HP:0001663
HumanPhenoAbnormal QT interval

SCN10A CACNA1S SCN5A

1.01e-046483HP:0031547
HumanPhenoPeriodic paralysis

CACNA1S SCN4A

1.18e-041182HP:0003768
HumanPhenoVentricular tachycardia

SCN10A CACNA1S SCN5A

1.27e-046983HP:0004756
HumanPhenoExercise-induced muscle fatigue

CACNA1S SCN4A

1.41e-041282HP:0009020
HumanPhenoAdrenocortical abnormality

CACNA1S CACNA1H SCN4A

1.76e-047783HP:0000849
HumanPhenoSecond degree atrioventricular block

CACNA1S SCN5A

2.24e-041582HP:0011706
HumanPhenoMuscle flaccidity

CACNA1S SCN4A

2.24e-041582HP:0010547
HumanPhenoAtrioventricular block

SCN10A CACNA1S SCN5A

3.09e-049383HP:0001678
HumanPhenoHeart block

SCN10A CACNA1S SCN5A

3.09e-049383HP:0001668
HumanPhenoBradycardia

SCN10A SCN4A SCN5A

3.61e-049883HP:0001662
HumanPhenoIncreased muscle fatiguability

CACNA1S SCN4A

3.64e-041982HP:0003750
HumanPhenoAbnormal cardiac exercise stress test

SCN10A SCN5A

3.64e-041982HP:0500018
HumanPhenoTrifascicular block

SCN10A SCN5A

4.91e-042282HP:0011715
HumanPhenoIncreased intramyocellular lipid droplets

CACNA1S SCN4A

5.37e-042382HP:0012240
HumanPhenoST segment elevation

SCN10A SCN5A

6.36e-042582HP:0012251
HumanPhenoAbnormal PR interval

CACNA1S SCN5A

6.36e-042582HP:0031593
HumanPhenoTorsade de pointes

SCN10A SCN5A

6.36e-042582HP:0001664
HumanPhenoSupraventricular tachycardia

SCN10A CACNA1S SCN5A

6.55e-0412083HP:0004755
HumanPhenoAbnormality of masticatory muscle

CACNA1S SCN4A

7.43e-042782HP:0410011
HumanPhenoParoxysmal ventricular tachycardia

SCN10A SCN5A

7.43e-042782HP:0004751
HumanPhenoNeoplasm of the adrenal cortex

CACNA1S SCN4A

7.99e-042882HP:0100641
HumanPhenoAbnormal atrioventricular conduction

SCN10A CACNA1S SCN5A

8.47e-0413183HP:0005150
HumanPhenoAtrioventricular nodal disease

SCN10A CACNA1S SCN5A

8.47e-0413183HP:0005142
HumanPhenoPremature ventricular contraction

CACNA1S SCN5A

8.58e-042982HP:0006682
HumanPhenoSick sinus syndrome

SCN10A SCN5A

8.58e-042982HP:0011704
HumanPhenoProlonged QTc interval

SCN10A SCN5A

8.58e-042982HP:0005184
HumanPhenoSupraventricular arrhythmia

SCN10A CACNA1S SCN5A

9.05e-0413483HP:0005115
HumanPhenoSinus bradycardia

SCN10A SCN5A

9.19e-043082HP:0001688
HumanPhenoAbnormal EKG

SCN10A CACNA1S SCN5A

9.45e-0413683HP:0003115
HumanPhenoHeart block

SCN10A CACNA1S SCN5A

9.45e-0413683HP:0012722
HumanPhenoAbnormality of jaw muscles

CACNA1S SCN4A

9.81e-043182HP:0045037
HumanPhenoAbnormal adrenal morphology

CACNA1S CACNA1H SCN4A

1.14e-0314583HP:0011732
HumanPhenoAbnormal endocrine morphology

CACNA1S CACNA1H SCN4A

1.14e-0314583HP:0031071
HumanPhenoMyotonia

CACNA1S SCN4A

1.18e-033482HP:0002486
HumanPhenoAbnormal T-wave

SCN10A SCN5A

1.40e-033782HP:0005135
HumanPhenoAbnormal ST segment

SCN10A SCN5A

1.55e-033982HP:0012249
HumanPhenoFatty replacement of skeletal muscle

CACNA1S SCN4A

1.55e-033982HP:0012548
HumanPhenoIncreased muscle lipid content

CACNA1S SCN4A

1.63e-034082HP:0009058
HumanPhenoHyperkalemia

CACNA1S SCN4A

1.63e-034082HP:0002153
HumanPhenoCardiac conduction abnormality

SCN10A CACNA1S SCN5A

1.72e-0316783HP:0031546
HumanPhenoUrinary incontinence

CACNA1H CACNA1G SCN4A

1.93e-0317483HP:0000020
HumanPhenoUrinary or fecal incontinence

CACNA1H CACNA1G SCN4A

1.93e-0317483HP:0007147
HumanPhenoImpaired continence

CACNA1H CACNA1G SCN4A

1.96e-0317583HP:0031064
HumanPhenoFirst degree atrioventricular block

SCN10A SCN5A

1.98e-034482HP:0011705
HumanPhenoAbnormal blood cation concentration

SCN10A CACNA1S SCN4A SCN5A

2.05e-0340184HP:0010929
HumanPhenoAbnormal cardiological findings

SCN10A CACNA1S SCN5A

2.06e-0317883HP:0003114
HumanPhenoAbnormal cardiac test

SCN10A CACNA1S SCN5A

2.10e-0317983HP:0500015
HumanPhenoAbnormal test result

SCN10A CACNA1S SCN5A

2.17e-0318183HP:0500014
HumanPhenoNeoplasm of the adrenal gland

CACNA1S SCN4A

2.25e-034782HP:0100631
HumanPhenoImpairment of activities of daily living

CACNA1H CACNA1G SCN4A

2.42e-0318883HP:0031058
HumanPhenoTachycardia

SCN10A CACNA1S SCN5A

2.45e-0318983HP:0001649
HumanPhenoAxial muscle weakness

CACNA1S SCN4A

2.55e-035082HP:0003327
HumanPhenoSecond trimester onset

SCN4A SCN5A

2.65e-035182HP:0034198
HumanPhenoAbnormal axial muscle morphology

CACNA1S SCN4A

2.75e-035282HP:0040286
HumanPhenoAbnormal muscle tissue metabolite concentration

CACNA1S SCN4A

2.97e-035482HP:0034370
HumanPhenoAbnormal blood ion concentration

SCN10A CACNA1S SCN4A SCN5A

3.03e-0344584HP:0003111
HumanPhenoPes valgus

SLC16A2 SCN4A

3.19e-035682HP:0008081
HumanPhenoAbnormality of cardiac conduction

SCN10A CACNA1S SCN4A SCN5A

3.21e-0345284HP:0001665
HumanPhenoRight bundle branch block

SCN10A SCN5A

3.30e-035782HP:0011712
HumanPhenoFatigable weakness of respiratory muscles

CACNA1S SCN4A

3.41e-035882HP:0030196
HumanPhenoCentrally nucleated skeletal muscle fibers

CACNA1S SCN4A

3.65e-036082HP:0003687
HumanPhenoMildly elevated creatine kinase

CACNA1S SCN4A

4.14e-036482HP:0008180
MousePhenothin ribs

POSTN CACNA1S

9.26e-059232MP:0004674
MousePhenoprolonged PQ interval

CACNA1G SCN5A

1.16e-0410232MP:0011953
MousePhenoimpaired ability to fire action potentials

SCN10A CACNA1G

2.00e-0413232MP:0002578
MousePhenosinus bradycardia

SCN10A SCN5A

2.33e-0414232MP:0010637
DomainChannel_four-helix_dom

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

1.34e-1457288IPR027359
Domain-

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

1.34e-14572881.20.120.350
DomainIon_trans_dom

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

4.22e-12114288IPR005821
DomainIon_trans

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

4.22e-12114288PF00520
DomainNa_channel_asu

SCN10A SCN4A SCN5A SCN7A

8.43e-1010284IPR001696
DomainNa_trans_assoc

SCN10A SCN4A SCN5A SCN7A

8.43e-1010284IPR010526
DomainNa_trans_assoc

SCN10A SCN4A SCN5A SCN7A

8.43e-1010284PF06512
DomainVDCCAlpha1

CACNA1S CACNA1H CACNA1G

3.60e-0710283IPR002077
DomainVDCC_T_a1

CACNA1H CACNA1G

6.50e-063282IPR005445
DomainIQ_motif_EF-hand-BS

SCN10A SCN4A SCN5A SCN7A

9.45e-0690284IPR000048
DomainMFS

SLC43A3 SLC16A2 SLC22A10

2.05e-0477283IPR011701
DomainMFS_1

SLC43A3 SLC16A2 SLC22A10

2.05e-0477283PF07690
DomainIQ

SCN4A SCN5A SCN7A

2.38e-0481283SM00015
DomainIQ

SCN10A SCN4A SCN5A

3.58e-0493283PS50096
DomainMFS_dom

SLC43A3 SLC16A2 SLC22A10

1.04e-03134283IPR020846
DomainGPCR_Rhodpsn_7TM

QRFPR OR10H5 MCHR1 OR10H2 OR10H1

2.90e-03670285IPR017452
Domain7tm_1

QRFPR OR10H5 MCHR1 OR10H2 OR10H1

3.03e-03677285PF00001
DomainG_PROTEIN_RECEP_F1_1

QRFPR OR10H5 MCHR1 OR10H2 OR10H1

3.19e-03685285PS00237
DomainG_PROTEIN_RECEP_F1_2

QRFPR OR10H5 MCHR1 OR10H2 OR10H1

3.31e-03691285PS50262
DomainGPCR_Rhodpsn

QRFPR OR10H5 MCHR1 OR10H2 OR10H1

3.33e-03692285IPR000276
DomainIQ

SCN10A SCN4A

5.05e-0371282PF00612
DomainEF-hand-dom_pair

CACNA1S SCN7A TPCN1

8.85e-03287283IPR011992
DomainMFS

SLC16A2 SLC22A10

1.14e-02108282PS50850
DomainOlfact_rcpt

OR10H5 OR10H2 OR10H1

2.05e-02393283IPR000725
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN10A SCN4A SCN5A SCN7A

1.97e-0731244M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN10A SCN4A SCN5A SCN7A

2.25e-0732244M27455
PathwayREACTOME_MUSCLE_CONTRACTION

SCN10A CACNA1H CACNA1G SCN4A SCN5A SCN7A

8.98e-07203246M5485
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1S CACNA1H CACNA1G

7.51e-0623243M47666
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA1S CACNA1H CACNA1G

9.73e-0625243M47948
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A

3.42e-05575247M29853
PathwayREACTOME_NCAM1_INTERACTIONS

CACNA1S CACNA1H CACNA1G

4.77e-0542243M7169
PathwayREACTOME_L1CAM_INTERACTIONS

SCN10A SCN4A SCN5A SCN7A

4.80e-05121244M872
PathwayREACTOME_CARDIAC_CONDUCTION

SCN10A SCN4A SCN5A SCN7A

6.36e-05130244M27454
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

CACNA1S CACNA1H CACNA1G

1.61e-0463243M11187
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR10H5 OR10H2 OR10H1

2.20e-0470243MM14984
PathwayREACTOME_SENSORY_PERCEPTION

OR10H5 RDH11 OR10H2 OR10H1

2.75e-04190244MM15687
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

SCN10A ADGRL3 SCN4A SCN5A SCN7A

3.29e-04367245M48346
PathwayREACTOME_SMOOTH_MUSCLE_CONTRACTION

CACNA1H CACNA1G

2.40e-0343242M1429
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1S CACNA1H CACNA1G

3.30e-03178243M2890
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A

1.54e-1113928716985003
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1S CACNA1H CACNA1G

1.63e-08728312900400
Pubmed

Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.

CACNA1S CACNA1H CACNA1G

2.61e-08828328330839
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN10A SCN4A SCN5A

3.91e-08928316382098
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1S CACNA1H CACNA1G

3.91e-08928316382099
Pubmed

Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in mice.

POSTN CACNA1G SCN5A

2.60e-071628321266775
Pubmed

A common genetic variant within SCN10A modulates cardiac SCN5A expression.

SCN10A SCN5A

6.25e-07228224642470
Pubmed

Voltage sensor charge loss accounts for most cases of hypokalemic periodic paralysis.

CACNA1S SCN4A

6.25e-07228219118277
Pubmed

Chronic deficit in nitric oxide elicits oxidative stress and augments T-type calcium-channel contribution to vascular tone of rodent arteries and arterioles.

CACNA1H CACNA1G

6.25e-07228223436820
Pubmed

Cav3.2 subunit underlies the functional T-type Ca2+ channel in murine hearts during the embryonic period.

CACNA1H CACNA1G

6.25e-07228214988077
Pubmed

Different distribution of Cav3.2 and Cav3.1 transcripts encoding T-type Ca(2+) channels in the embryonic heart of mice.

CACNA1H CACNA1G

6.25e-07228221079360
Pubmed

Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants.

SCN4A SCN5A

6.25e-07228211834499
Pubmed

Voltage-dependent Ca2+ release is impaired in hypokalemic periodic paralysis caused by CaV1.1-R528H but not by NaV1.4-R669H.

CACNA1S SCN4A

6.25e-07228235759432
Pubmed

Role of T-type calcium channel subunits in post-myocardial infarction remodelling probed with genetically engineered mice.

CACNA1H CACNA1G

6.25e-07228221622683
Pubmed

Deficiency of T-type Ca2+ channels Cav3.1 and Cav3.2 has no effect on angiotensin II-induced hypertension but differential effect on plasma aldosterone in mice.

CACNA1H CACNA1G

6.25e-07228231042060
Pubmed

Inhibition of Cav 3.2 calcium channels: A new target for colonic hypersensitivity associated with low-grade inflammation.

SCN10A CACNA1H

6.25e-07228230714145
Pubmed

The Ca(v)3.1 T-type calcium channel is required for neointimal formation in response to vascular injury in mice.

CACNA1H CACNA1G

6.25e-07228222886848
Pubmed

Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat.

SCN10A SCN5A

6.25e-07228215047701
Pubmed

Ca(v)3.2 T-type Ca2+ channel-dependent activation of ERK in paraventricular thalamus modulates acid-induced chronic muscle pain.

CACNA1H CACNA1G

6.25e-07228220685979
Pubmed

Absence of ion channels CACN1AS and SCN4A mutations in thyrotoxic hypokalemic periodic paralysis.

CACNA1S SCN4A

6.25e-07228215072700
Pubmed

Deletion of T-type calcium channels Cav3.1 or Cav3.2 attenuates endothelial dysfunction in aging mice.

CACNA1H CACNA1G

6.25e-07228229082441
Pubmed

Mutations associated with hypokalemic periodic paralysis: from hotspot regions to complete analysis of CACNA1S and SCN4A genes.

CACNA1S SCN4A

6.25e-07228234608571
Pubmed

Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome.

SCN10A SCN5A

6.25e-07228224998131
Pubmed

Genotype and phenotype analysis of patients with sporadic periodic paralysis.

CACNA1S SCN4A

6.25e-07228221841462
Pubmed

[Decreased mRNA expressions of T-type channel alpha1H and alpha1G in the sperm of varicocele patients and their implication].

CACNA1H CACNA1G

6.25e-07228222574369
Pubmed

Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif.

SCN4A SCN5A

6.25e-07228230944319
Pubmed

From GWAS to function: genetic variation in sodium channel gene enhancer influences electrical patterning.

SCN10A SCN5A

6.25e-07228224360055
Pubmed

Comparable clinical characteristics in Brugada syndrome patients harboring SCN5A or novel SCN10A variants.

SCN10A SCN5A

6.25e-07228231292628
Pubmed

Blockade of T-type Ca(2+) channels inhibits human ovarian cancer cell proliferation.

CACNA1H CACNA1G

6.25e-07228221438841
Pubmed

Mutation analysis of CACNA1S and SCN4A in patients with hypokalemic periodic paralysis.

CACNA1S SCN4A

6.25e-07228226252573
Pubmed

T-type voltage-activated calcium channel Cav3.1, but not Cav3.2, is involved in the inhibition of proliferation and apoptosis in MCF-7 human breast cancer cells.

CACNA1H CACNA1G

6.25e-07228222469755
Pubmed

β-Adrenergic stimulation increases Cav3.1 activity in cardiac myocytes through protein kinase A.

CACNA1H CACNA1G

6.25e-07228222808078
Pubmed

The Low-Threshold Calcium Channel Cav3.2 Determines Low-Threshold Mechanoreceptor Function.

SCN10A CACNA1H

6.25e-07228225600872
Pubmed

Single nucleotide polymorphisms of SCN5A and SCN10A genes increase the risk of ventricular arrhythmias during myocardial infarction.

SCN10A SCN5A

6.25e-07228232330377
Pubmed

5,6-EET potently inhibits T-type calcium channels: implication in the regulation of the vascular tone.

CACNA1H CACNA1G

1.87e-06328224327205
Pubmed

Hypokalemic Periodic Paralysis

CACNA1S SCN4A

1.87e-06328220301512
Pubmed

Ethanol inhibition of a T-type Ca²+ channel through activity of protein kinase C.

CACNA1H CACNA1G

1.87e-06328223488970
Pubmed

Fibromodulin modulates myoblast differentiation by controlling calcium channel.

CACNA1S CACNA1G

1.87e-06328229913145
Pubmed

Differential effect of T-type voltage-gated Ca2+ channel disruption on renal plasma flow and glomerular filtration rate in vivo.

CACNA1H CACNA1G

1.87e-06328224966091
Pubmed

T-type channels: release a brake, engage a gear.

CACNA1H CACNA1G

1.87e-06328226488564
Pubmed

T-type, but not L-type, voltage-gated calcium channels are dispensable for lymphatic pacemaking and spontaneous contractions.

CACNA1H CACNA1G

1.87e-06328231919478
Pubmed

Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria.

CACNA1H CACNA1G

1.87e-06328225825486
Pubmed

Differential interactions of Na+ channel toxins with T-type Ca2+ channels.

CACNA1H CACNA1G

1.87e-06328218591418
Pubmed

Modulation of skeletal and cardiac voltage-gated sodium channels by calmodulin.

SCN4A SCN5A

1.87e-06328215746172
Pubmed

Identification of the t-type calcium channel (Ca(v)3.1d) in developing mouse heart.

CACNA1H CACNA1G

1.87e-06328211230107
Pubmed

Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice.

CACNA1H CACNA1G

1.87e-06328211897840
Pubmed

Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation.

CACNA1H CACNA1G

1.87e-06328228846697
Pubmed

Caveolin-3 regulates protein kinase A modulation of the Ca(V)3.2 (alpha1H) T-type Ca2+ channels.

CACNA1H CACNA1G

1.87e-06328221084288
Pubmed

Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures.

CACNA1H CACNA1G

1.87e-06328233547341
Pubmed

Electric field stimulation unmasks a subtle role for T-type calcium channels in regulating lymphatic contraction.

CACNA1H CACNA1G

1.87e-06328237739992
Pubmed

Calmodulin regulates Cav3 T-type channels at their gating brake.

CACNA1H CACNA1G

1.87e-06328228972185
Pubmed

Inhibition of G protein-gated K+ channels by tertiapin-Q rescues sinus node dysfunction and atrioventricular conduction in mouse models of primary bradycardia.

CACNA1G SCN5A

1.87e-06328232555258
Pubmed

Mutation spectrum and health status in skeletal muscle channelopathies in Japan.

CACNA1S SCN4A

1.87e-06328232660787
Pubmed

Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability.

CACNA1H CACNA1G

1.87e-06328211927664
Pubmed

ZnT-1 enhances the activity and surface expression of T-type calcium channels through activation of Ras-ERK signaling.

CACNA1H CACNA1G

1.87e-06328222572848
Pubmed

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.

SCN4A SCN5A

1.87e-06328220038812
Pubmed

High prevalence of concealed Brugada syndrome in patients with atrioventricular nodal reentrant tachycardia.

SCN10A SCN5A

1.87e-06328225998140
Pubmed

Genome-wide association studies of the PR interval in African Americans.

SCN10A SCN5A

3.75e-06428221347284
Pubmed

Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms.

CACNA1H CACNA1G

3.75e-06428231800012
Pubmed

Functional importance of L- and P/Q-type voltage-gated calcium channels in human renal vasculature.

CACNA1H CACNA1G

3.75e-06428221788606
Pubmed

Evolution and diversity of mammalian sodium channel genes.

SCN10A SCN7A

3.75e-06428210198179
Pubmed

Pharmacogenetics of antiepileptic drug efficacy in childhood absence epilepsy.

CACNA1H CACNA1G

3.75e-06428228165634
Pubmed

T-type Ca2+ channels elicit pro-proliferative and anti-apoptotic responses through impaired PP2A/Akt1 signaling in PASMCs from patients with pulmonary arterial hypertension.

CACNA1H CACNA1G

3.75e-06428228655554
Pubmed

Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.

SCN10A SCN5A

6.24e-06528222706305
Pubmed

Developmental expression patterns of alpha1H T-type Ca2+ channels during spermatogenesis and organogenesis in mice.

CACNA1H CACNA1G

6.24e-06528212060068
Pubmed

Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk.

SCN10A SCN5A

6.24e-06528223463857
Pubmed

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.

SCN10A SCN5A

6.24e-06528223872634
Pubmed

T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B.

CACNA1H CACNA1G

6.24e-06528229720258
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN4A SCN5A

6.24e-06528217724025
Pubmed

Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts.

SCN10A SCN5A

1.31e-05728223139255
Pubmed

Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord.

CACNA1H CACNA1G

1.74e-05828234478646
Pubmed

Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins.

SCN4A SCN5A

1.74e-0582829412493
Pubmed

Intracellular calcium plays an essential role in cardiac development.

CACNA1H CACNA1G

1.74e-05828212761855
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN4A SCN5A

2.24e-05928215746173
Pubmed

Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction.

CACNA1G SCN5A

2.80e-051028232672536
Pubmed

Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage.

CACNA1H CACNA1G

2.80e-051028224778262
Pubmed

Cardiac disease and arrhythmogenesis: Mechanistic insights from mouse models.

CACNA1G SCN5A

3.42e-051128227766308
Pubmed

Genome-wide association study of PR interval.

SCN10A SCN5A

4.10e-051228220062060
Pubmed

A missense mutation of ErbB2 produces a novel mouse model of stillbirth associated with a cardiac abnormality but lacking abnormalities of placental structure.

CACNA1G SCN5A

4.10e-051228232492036
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN10A SCN5A

4.85e-051328215123669
Pubmed

Canonical wnt signaling regulates atrioventricular junction programming and electrophysiological properties.

POSTN SCN5A

4.85e-051328225599332
Pubmed

Several common variants modulate heart rate, PR interval and QRS duration.

SCN10A SCN5A

5.65e-051428220062063
Pubmed

Identification of three novel genetic variations associated with electrocardiographic traits (QRS duration and PR interval) in East Asians.

SCN10A SCN5A

7.45e-051628225035420
Pubmed

Mechanical loading is required for initiation of extracellular matrix deposition at the developing murine myotendinous junction.

POSTN CACNA1S

7.45e-051628236709857
Pubmed

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction.

SCN10A SCN5A

8.44e-051728221076409
Pubmed

Genetic determinants of P wave duration and PR segment.

SCN10A SCN5A

8.44e-051728224850809
Pubmed

Calcium handling precedes cardiac differentiation to initiate the first heartbeat.

CACNA1H CACNA1G

8.44e-051728227725084
Pubmed

An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo.

SCN10A SCN5A

9.49e-051828231666509
Pubmed

Misexpression of Tbx18 in cardiac chambers of fetal mice interferes with chamber-specific developmental programs but does not induce a pacemaker-like gene signature.

POSTN SCN5A

9.49e-051828227180262
Pubmed

The formation and function of the cardiac conduction system.

CACNA1G SCN5A

1.30e-042128226786210
Pubmed

Congenital heart defect causing mutation in Nkx2.5 displays in vivo functional deficit.

CACNA1S SCN5A

1.30e-042128228302382
Pubmed

Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays.

SCN4A SCN5A

1.56e-042328216637659
Pubmed

Brugada Syndrome

SCN10A SCN5A

1.71e-042428220301690
Pubmed

The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development.

SCN10A SCN5A

2.68e-043028239366945
Pubmed

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria.

CACNA1G SCN5A

2.86e-043128217473172
Pubmed

LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation.

CACNA1H SCN5A

3.45e-043428226378152
Pubmed

Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

SLC44A2 CACNA1H SLC43A3 RDH11

3.73e-0443028416303743
Pubmed

A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.

OR10H5 OR10H2 OR10H1

5.93e-0420528312040188
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

SLC44A2 RDH11 DNAJC16 SURF4

6.52e-0449928422810586
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR10H5 OR10H2 OR10H1

7.18e-0421928312213199
InteractionSLC44A1 interactions

OR10H2 OR10H1 SCN4A

3.13e-0546273int:SLC44A1
InteractionSCN10A interactions

SCN10A SCN5A

9.44e-0511272int:SCN10A
InteractionSARAF interactions

SLC13A2 OR10H2 OR10H1 SCN4A

1.44e-04202274int:SARAF
InteractionSCN11A interactions

SCN10A SCN5A

1.80e-0415272int:SCN11A
InteractionSCN8A interactions

SCN4A SCN5A

3.24e-0420272int:SCN8A
InteractionSYNGR1 interactions

SLC43A3 SLC16A2 SURF4

4.10e-04109273int:SYNGR1
InteractionPOMK interactions

RDH11 SURF4 SCN4A XPOT

4.40e-04271274int:POMK
InteractionP2RY2 interactions

DNAJC16 SURF4 TPCN1

4.43e-04112273int:P2RY2
InteractionCACNA1D interactions

SCN10A SCN5A

4.68e-0424272int:CACNA1D
InteractionTSPAN15 interactions

SLC43A3 SURF4 SCN4A TPCN1

4.71e-04276274int:TSPAN15
InteractionSLC29A1 interactions

OR10H2 OR10H1 SCN4A

5.56e-04121273int:SLC29A1
InteractionTMEM268 interactions

RDH11 OR10H2

5.94e-0427272int:TMEM268
InteractionABHD6 interactions

OR10H2 OR10H1

5.94e-0427272int:ABHD6
InteractionSLC12A6 interactions

OR10H2 OR10H1 DNAJC16

5.97e-04124273int:SLC12A6
Cytoband19p13.1

SLC44A2 OR10H2 OR10H1

3.45e-064828319p13.1
CytobandEnsembl 112 genes in cytogenetic band chr19p13

SLC44A2 OR10H5 OR10H2 OR10H1

1.32e-03797284chr19p13
GeneFamilySodium voltage-gated channel alpha subunits

SCN10A SCN4A SCN5A

1.72e-0792431203
GeneFamilyCalcium voltage-gated channel subunits

CACNA1S CACNA1H CACNA1G

5.24e-0626243253
GeneFamilyOlfactory receptors, family 10

OR10H5 OR10H2 OR10H1

8.90e-0566243157
GeneFamilySolute carriers

SLC44A2 SLC43A3 SLC13A2 SLC16A2 SLC22A10

1.46e-04395245752
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

POSTN CACNA1H CACNA1G DSEL ADGRL3 SCN7A TPCN1

2.96e-05773267gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000

POSTN CACNA1G DSEL SCN7A TPCN1

4.82e-05336265gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000
CoexpressionAtlaskidney_P0_CapMes_Crym_k-means-cluster#1_top-relative-expression-ranked_1000

OR10H5 OR10H2

9.44e-0512262gudmap_kidney_P0_CapMes_Crym_k1_1000
CoexpressionAtlasdev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_100

POSTN DSEL ADGRL3

1.90e-0492263gudmap_dev gonad_e11.5_F_GonMes_Sma_100
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#2_top-relative-expression-ranked_1000

OR10H5 OR10H2

1.94e-0417262gudmap_kidney_P4_CapMesRenVes_Crym_k2_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

POSTN CACNA1H CACNA1G SLC43A3 ADGRL3 TPCN1

2.89e-04777266gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN10A UCN3 SLC22A10 SCN5A

3.58e-061682849adb91ae87a009db7ed83e0d3ab964acc38708f1
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN CACNA1G SLC43A3 SCN7A

5.83e-061902848cb950effc449ae59a915132ecc079be54d1acfe
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN CACNA1G SLC43A3 SCN7A

5.83e-0619028417a73a658fb30a4322b31e38db7b240023738f29
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN CACNA1G SLC43A3 SCN7A

5.83e-061902845dfbd064ab1f8a0b18b5975c47f8e79697f3db15
ToppCellfacs-Heart-RA-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN SLC43A3 SLC16A2 SCN7A

6.33e-06194284c422aeddb4e949a22f731da675bdf91dee86ba61
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_C1ql2_Cdh13|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

QRFPR CACNA1H SLC16A2

8.37e-051362831f3000d5f105c87c80f8ae1dd2264bcd7f757a9c
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

QRFPR CACNA1H MCHR1

9.72e-051432835fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CACNA1H SCN5A SCN7A

1.01e-0414528378f5f4b96420c7f391e4d32a9ed151ed95fad90b
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

QRFPR SCN5A SCN7A

1.01e-04145283590ba937c741ae67460f303eca88b1cd3ac87f64
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Fam159b|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

UCN3 SCN5A SCN7A

1.10e-0414928398ae408d2d0347865875ff8bbd89d359decea526
ToppCellControl-Epithelial-Ionocyte|Epithelial / Disease state, Lineage and Cell class

POSTN CACNA1H RDH11

1.23e-041552834b9369b203a4d7071c56d3d8e6b450e9a0121c41
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H UCN3 SCN4A

1.35e-04160283f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S CACNA1H CACNA1G

1.38e-0416128360f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

POSTN ADGRL3 SLC22A10

1.43e-04163283ba7d02db0f0e2f9916ec8db52c067c87b6917c23
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

POSTN MCHR1 SLC16A2

1.56e-04168283aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCellLA-16._Neuronal|LA / Chamber and Cluster_Paper

POSTN ADGRL3 SCN7A

1.56e-04168283c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H UCN3 SCN7A

1.59e-04169283c5015ddb838849ea892a2cae5a739b554eb6d793
ToppCellfacs-Marrow-B-cells-24m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S CACNA1H UCN3

1.68e-0417228365b8935a972bf00b7a10dc2d442128fc0ed78bcb
ToppCellILEUM-inflamed-(4)_Mast|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SLC43A3 SLC13A2 SCN7A

1.68e-04172283be82f749f4b1049ae8832facc052082cf5463c11
ToppCellfacs-Marrow-B-cells-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S CACNA1H UCN3

1.68e-04172283a7fd4d61fb5017dce001d69d6b9a01e6cdf58828
ToppCellILEUM-inflamed-(4)_Mast_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SLC43A3 SLC13A2 SCN7A

1.68e-041722837185b28282412f3a464b2a8ad5605475a1a31358
ToppCell(6)_Endothelial_cells-(6)_Endothelial-E|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

POSTN ADGRL3 SLC22A10

1.73e-041742834a1b67ce5ea353b3f81f59fa57da07668146afca
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S CACNA1H SCN5A

1.73e-041742833f4277763e312b46ebd4401ea4a2f5d4c850c768
ToppCelldroplet-Lung-nan-21m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S CACNA1H SCN5A

1.73e-04174283fad66d1a8407574b6a835e0bdb824a53afa58650
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-plasma_cell-plasma_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1S CACNA1H SCN5A

1.76e-0417528328b29f844fa46fe579ddc19039fb2d9dc5f48f3b
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-plasma_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1S CACNA1H SCN5A

1.76e-04175283ac96ca9ca309b0d72a2f5af6a3b02c7f80755750
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

MCHR1 SLC16A2 SCN7A

1.82e-04177283cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

MCHR1 SLC16A2 SCN7A

1.82e-04177283db222faaecbe5600da39277243c4e7e764eb63c9
ToppCelldroplet-Bladder-nan-24m-Epithelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN SLC43A3 SCN7A

1.89e-041792833d6bb3cfe89d60f2f00aead9341f9967e5313763
ToppCellControl-Stromal-SMC|Control / Disease state, Lineage and Cell class

CACNA1H ADGRL3 SCN7A

1.89e-041792831378051bc62009eec2dbecf3d5d89baedbeb84eb
ToppCellAT1-AT2_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CACNA1H ADGRL3 SCN5A

1.92e-041802833c7b2033821f9e34e2924bd8655f566edcbcc7d3
ToppCellP15-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SLC43A3 ADGRL3 SCN7A

1.92e-04180283410ea13a9c00cf54b4d47c72404dfe893c086d87
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1H ADGRL3 SCN7A

1.95e-0418128333cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCellPericytes-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

CACNA1S CACNA1H ADGRL3

1.98e-0418228346c213597445b1f4f09dc367f27702d24b201daf
ToppCellPericytes-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CACNA1H ADGRL3 SCN7A

2.01e-04183283d04deef7cd4e1738227a6593b84874ce0168c773
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN ADGRL3 XPOT

2.01e-041832835377b4fbd8fdfe68933b4c0965aa9525f7f31591
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN DSEL ADGRL3

2.01e-04183283af8d86f15a549064530d94bd47081daf59d58ecd
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

POSTN CACNA1H ADGRL3

2.14e-04187283464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs|metastatic_Lymph_Node / Location, Cell class and cell subclass

POSTN MCHR1 SCN5A

2.14e-04187283e04fb35f2f5b120659d06b5ae427ab1ec56d5c36
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN CACNA1G ADGRL3

2.18e-04188283997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCelldroplet-Spleen-nan-21m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S CACNA1H SURF4

2.18e-0418828370184b14160b71a1fecd7f195e5a16c5937738a2
ToppCellfacs-Heart-RA-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 SLC16A2 SCN7A

2.21e-041892837c6d586f352d0d44c24079e76272cb3a545441b5
ToppCellfacs-Heart-RA-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 SLC16A2 SCN7A

2.21e-041892835438baaa3056fec46d59f75f03f27a93601936c1
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S CACNA1H SURF4

2.25e-04190283992539c380576bf810c00a5f926cf1ee7d57dcf5
ToppCell3'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN CACNA1H ADGRL3

2.25e-04190283591310e615700321a010a4b90405cbbbbdb3aade
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

POSTN ADGRL3 SCN7A

2.28e-041912835271198116343c07202649889057e5774d7fdde3
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 SLC16A2 SCN7A

2.28e-041912836cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCelldroplet-Fat-Gat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 SLC16A2 SCN7A

2.28e-04191283850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 SLC16A2 SCN7A

2.28e-041912838b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

POSTN SLC16A2 ADGRL3

2.32e-041922834ed5040594ba2d0639f0990697504ecef872ca70
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

POSTN SLC16A2 ADGRL3

2.32e-04192283d4f5d6653564c2c5d0f5f7c932d89cb1b1412844
ToppCellControl-Myeloid-MoAM4|Control / Disease group,lineage and cell class (2021.01.30)

SLC43A3 SLC16A2 TPCN1

2.32e-041922831da7c303a2e36af4a9d8ec30a11380d9b1897922
ToppCellfacs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 SURF4 SCN7A

2.35e-04193283735a72fac16397edde95e8eefa6f83caeb5ee5df
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MCHR1 SLC16A2 SCN7A

2.35e-04193283b05361ffe111a38cfa26eb86e4ae62c15ac99b7b
ToppCelldroplet-Heart-nan-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 SLC16A2 SCN7A

2.35e-041932830ca0439dfdcb2361ca8d1015fb874a5b5c635d31
ToppCelldroplet-Heart-nan-24m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 SLC16A2 SCN7A

2.35e-04193283d08919db9601941569b9a143dad4d8e6f56a4389
ToppCellfacs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 SURF4 SCN7A

2.35e-04193283ff901d2f3d7a511639c1e3b76058896c0d8a8602
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

CACNA1H ADGRL3 SCN7A

2.35e-041932839104b572d9c3c99080e4b7455993fbb944bf117d
ToppCellfacs-Heart-LA-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN SLC43A3 SCN7A

2.35e-04193283124364adb3ded77282d449dd2cb039e6f2403a39
ToppCellfacs-GAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 SLC16A2 SCN7A

2.39e-041942839709dc95fb6982b6a0467b507845d5bc17252e3e
ToppCellfacs-SCAT-Fat-3m-Mesenchymal|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN SLC43A3 SCN7A

2.39e-0419428314b614f039bc866a1348a2728a68b7d254c7748c
ToppCellfacs-GAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 SLC16A2 SCN7A

2.39e-0419428393b7a9065430740ec31fce4e8c14ffccb498591d
ToppCellfacs-Heart-RA-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 SLC16A2 SCN7A

2.39e-0419428348063c9fe3e12aeff0707acada1baa2f8621f093
ToppCellfacs-SCAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN SLC43A3 SCN7A

2.39e-0419428368c7bfead1158641928cc276f599b4a79e06c73c
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 ADGRL3 SCN7A

2.39e-04194283f159ef8541d75a4e98468947f231bb463bec922c
ToppCellfacs-Heart-LA-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN SLC43A3 SCN7A

2.39e-041942839a5dd7ae6de72a000cf9a0d42f6b0884fa43f345
ToppCellfacs-GAT-Fat-18m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 SLC16A2 SCN7A

2.39e-041942830d2e65b44e3f143971c2fd24c4552f042b049cfa
ToppCellfacs-SCAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN SLC43A3 SCN7A

2.39e-04194283f6aeae6a1e4017e341323fd4784c9e3bae00552b
ToppCellfacs-Heart-LA-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN SLC43A3 SCN7A

2.39e-0419428334b54bea013c8c724fadae357e29953c291bfce1
ToppCellfacs-Heart-RA-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC43A3 SLC16A2 SCN7A

2.39e-041942834f31d2cf7eb37b45fefc4da5b41aac0bfdd847b3
ToppCelldroplet-Spleen-SPLEEN-30m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S CACNA1H SURF4

2.42e-04195283f9a90cd7b4e99a0947fdb3645f7787d02b0f7ca0
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

POSTN SLC16A2 SCN7A

2.46e-04196283525d6c8a277364e624e7cc586275f8a891436b57
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN DSEL ADGRL3

2.46e-04196283a7adc0e0baef261d0937e4e8351321d41beca82f
ToppCellEndothelial-capillary_endothelial_cell_(Cap1)|World / Lineage, Cell type, age group and donor

POSTN ADGRL3 SLC22A10

2.46e-041962830ce3ed27d2b9276390952652c17a8d6de13add36
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

SLC43A3 DSEL SLC13A2

2.50e-041972831a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCellMonocytes-NUPR1+_Monocytes|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SLC43A3 RDH11 TPCN1

2.50e-041972838a058c9d9285acd7cf2fb8e34f7602a86b5d6c89
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_capillary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

POSTN ADGRL3 SLC22A10

2.54e-041982831d30a1f73b6d6d838f49751402a29c5ef54aa81f
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1H ADGRL3 SCN5A

2.57e-04199283534dcfe8b65ad92bb8d749d1c7036ad4807e09cd
ToppCellTracheal-10x3prime_v2-Stromal-Schwann|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SLC44A2 ADGRL3 SCN7A

2.57e-041992838dc65662c3ca1db2ba0091332f0658abc0afc5de
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1H ADGRL3 SCN5A

2.57e-04199283056a28c36cd58dc695a5ae6f29b62135d6aad819
ToppCellTracheal-10x3prime_v2-Stromal-Schwann-Schwann_nonmyelinating|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SLC44A2 ADGRL3 SCN7A

2.57e-04199283a92718a3f1153b8d2196fd343ed5bc0ebc98cad7
ToppCellBiopsy_Control_(H.)-Mesenchymal-Smooth_Muscle_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

CACNA1H ADGRL3 SCN7A

2.57e-0419928331c781a1787e5140fb3f611823cbab4d13d02dfa
ToppCell(5)_Fibroblasts-(5)_Fibroblast-H|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

SLC43A3 SURF4 XPOT

2.61e-042002830ebc54d19873a2b7b6d12b81559cb12abd73b90c
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Fos_(dSPN,_IEG+)-|Striatum / BrainAtlas - Mouse McCarroll V32

UCN3 SCN4A

3.64e-0445282cce61a18a2d2ac9c3113ef7d9fe8adf70bad773c
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Fos_(dSPN,_IEG+)|Striatum / BrainAtlas - Mouse McCarroll V32

UCN3 SCN4A

3.64e-044528208e956e0a428432382ecc13f293f20154fac042c
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

QRFPR SCN7A

1.01e-03752823bc5df14f21c1c93c2a0fd5fc47bc5d146ba87a2
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_2|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

CACNA1H MCHR1

1.38e-03882823a92f76e4db86486cb265301e6056af791a11a63
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_B3-7|TCGA-Thymus / Sample_Type by Project: Shred V9

OR10H5 OR10H1

1.78e-031002827a0220df4020aeb16fecbbe9b46f3ccf86c62dd8
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

POSTN SCN4A

1.92e-03104282424a58b04c8b5108b70f15d8353c8e4b9db1e730
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

POSTN SCN4A

1.92e-0310428211d91471b6c4fa6b00a91d9fd4db72ee60d1f801
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

POSTN SCN4A

1.92e-031042829b05ae514437eb0c8b1b23607ae8cbc371ffa85b
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MCHR1 SCN7A

2.26e-0311328234ae3dec5ec7585d155ea61de6adc42aa4f45226
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MCHR1 SCN7A

2.26e-0311328279ba2eb8f85e5da4c19c838df881c18ffdc450fb
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MCHR1 SCN7A

2.26e-0311328291d55fe6fb1c1472867d74461f5b9e4f17db01cd
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

POSTN CACNA1H

2.34e-031152827a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

POSTN CACNA1H

2.34e-03115282c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

POSTN CACNA1H

2.34e-03115282ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

POSTN SLC43A3

2.47e-031182823cebd17f4688cd43fe1283dc60957e87d5536810
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

POSTN SLC43A3

2.47e-0311828271f63efc641cd07c870f7695118fb244929c1536
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Entopeduncular / BrainAtlas - Mouse McCarroll V32

POSTN SLC43A3

2.47e-0311828261b00b001edb1954a5fffaf4dfe71708124a45e5
ComputationalGenes in the cancer module 71.

SLC13A2 SLC16A2

3.08e-0422132MODULE_71
Druglamotrigine

SCN10A CACNA1S CACNA1H CACNA1G SLC43A3 SCN4A SCN5A SCN7A TPCN1

1.07e-14116289CID000003878
Drugbepridil

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

1.99e-12126288CID000002351
Druggabapentin

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

2.14e-11169288CID000003446
Drugisradipine

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN7A TPCN1

2.80e-11100287CID000003784
DrugNSC7524

SCN10A CACNA1S CACNA1H CACNA1G UCN3 SCN4A SCN5A SCN7A

3.87e-11182288CID000005657
Drugphenytoin

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

1.70e-10219288CID000001775
Drugprocaine

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN7A TPCN1

5.67e-10153287CID000004914
Drugriluzole

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A

1.39e-09174287CID000005070
Drugpyraclofos

CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A

3.06e-09106286CID000093460
DrugZonisamide

CACNA1H CACNA1G SCN4A SCN5A

4.31e-0917284DB00909
Drugsodium

SCN10A CACNA1S CACNA1H SLC43A3 MCHR1 SLC13A2 SLC16A2 SCN4A SCN5A SCN7A TPCN1

6.60e-099442811CID000000923
Drugzonisamide

SCN10A CACNA1H CACNA1G SCN4A SCN7A

1.19e-0862285CID000005734
DrugAC1L1MOZ

SCN10A SCN4A SCN5A SCN7A

3.15e-0827284CID000031958
Drugtocainide

SCN10A SCN4A SCN5A SCN7A

4.90e-0830284CID000038945
Drugoxcarbazepine

CACNA1H SLC43A3 SCN4A SCN5A

4.90e-0830284CID000034312
Drugcarbamazepine

SCN10A SLC43A3 SLC13A2 SCN4A SCN5A SCN7A

7.09e-08179286CID000002554
Drugverapamil

SCN10A CACNA1S CACNA1H CACNA1G SCN4A SCN5A SCN7A TPCN1

9.25e-08490288CID000002520
DrugCinnarizine

CACNA1S CACNA1H CACNA1G

1.39e-079283DB00568
DrugMibefradil

CACNA1S CACNA1H CACNA1G

2.73e-0711283DB01388
Drugpilsicainide

SCN10A SCN4A SCN5A SCN7A

2.88e-0746284CID000004820
Drugtetralol

CACNA1H CACNA1G SCN5A

4.72e-0713283CID000010747
DrugCinildipine

CACNA1S CACNA1H CACNA1G TPCN1

6.43e-0756284CID000002752
Drugisovalerate

CACNA1S CACNA1H CACNA1G SCN5A TPCN1

7.97e-07143285CID000010430
Drugnilvadipine

CACNA1S CACNA1H CACNA1G TPCN1

8.51e-0760284CID000004494
DrugVerapamil

CACNA1S CACNA1G SCN5A

9.23e-0716283DB00661
Druglercanidipine

CACNA1S CACNA1H CACNA1G TPCN1

1.04e-0663284CID000065866
Drugmibefradil

CACNA1S CACNA1H SCN5A TPCN1

1.10e-0664284CID000060662
DrugAC1L1CQC

SCN10A SCN4A SCN5A SCN7A

1.18e-0665284CID000002012
Drugmexiletine

SCN10A SCN4A SCN5A SCN7A

1.25e-0666284CID000004178
Drugdisopyramide

SCN10A SCN4A SCN5A SCN7A

1.25e-0666284CID000003114
Druggallopamil

CACNA1S CACNA1H CACNA1G TPCN1

1.33e-0667284CID000001234
Druglidocaine

SCN10A CACNA1S SCN4A SCN5A SCN7A

1.39e-06160285CID000003676
Drugdibucaine

SCN10A SCN4A SCN5A SCN7A

1.41e-0668284CID000003025
DrugHexylcaine

SCN10A SCN5A

1.46e-062282DB00473
DrugFlecainide

SCN4A SCN5A

1.46e-062282DB01195
DrugGBR 12909

SCN10A MCHR1 SCN4A SCN7A

1.50e-0669284CID000003455
DrugAC1L2AC7

CACNA1S CACNA1H CACNA1G TPCN1

1.50e-0669284CID000068733
Drugdiprafenone

SCN10A SCN4A SCN7A

1.59e-0619283CID000071249
Drugflecainide

SCN10A SCN4A SCN5A SCN7A

1.68e-0671284CID000003355
DrugCAS 298-57-7

CACNA1S CACNA1H CACNA1G TPCN1

1.88e-0673284CID000002761
Drugethosuximide

CACNA1S CACNA1H CACNA1G TPCN1

1.98e-0674284CID000003291
Drugpotassium

SCN10A CACNA1S CACNA1H CACNA1G UCN3 SCN4A SCN5A SCN7A TPCN1

2.03e-061008289CID000000813
Drugnisoldipine

CACNA1S CACNA1H CACNA1G TPCN1

2.45e-0678284CID000004499
Drugdihydropyridine

CACNA1S CACNA1H CACNA1G SCN4A TPCN1

3.49e-06193285CID000104822
DrugAC1NT1AF

SCN10A SCN4A SCN7A

3.76e-0625283CID005322157
DrugPirmenolum

SCN10A SCN4A SCN7A

4.25e-0626283CID000004853
DrugDibucaine

SCN10A SCN5A

4.37e-063282DB00527
Drug1,3-dioxoisoindoline-5-carboxamide

CACNA1H CACNA1G

4.37e-063282CID010679219
Drugnefopam

SCN10A SCN4A SCN7A

4.78e-0627283CID000004450
DrugPbTx-1

SCN10A SCN4A SCN7A

4.78e-0627283CID006437089
Drugparaben

SCN10A SCN4A SCN7A

5.35e-0628283CID000007175
Drugmanidipine

CACNA1S CACNA1H CACNA1G TPCN1

5.39e-0695284CID000004008
DrugGTP[S]

SCN10A CACNA1S CACNA1H MCHR1 SCN4A SCN7A TPCN1

5.65e-06591287CID000001764
Drugvalproate

CACNA1S CACNA1H CACNA1G SLC43A3 SCN4A TPCN1

5.82e-06381286CID000003121
Drugpropafenone

SCN10A SCN4A SCN5A SCN7A

6.10e-0698284CID000004932
Drugnitrendipine

CACNA1S CACNA1H CACNA1G TPCN1

6.10e-0698284CID000004507
Drugloperamide

CACNA1S CACNA1H CACNA1G TPCN1

8.03e-06105284CID000003954
DrugNSC93767

SCN10A SCN4A SCN7A

8.07e-0632283CID000005658
DrugLidocaine

SCN10A SCN5A

8.74e-064282DB00281
DrugCNS 1145

CACNA1S CACNA1H CACNA1G

8.87e-0633283CID000190902
DrugIHC-64

CACNA1S CACNA1H CACNA1G

8.87e-0633283CID000162753
Drug5-hydroxypropafenone

SCN10A SCN4A SCN7A

9.72e-0634283CID000107927
Drugtetradotoxin

SCN10A CACNA1H CACNA1G SCN4A SCN5A SCN7A

1.13e-05428286CID000020382
Drugbenzocaine

SCN10A SCN4A SCN7A

1.26e-0537283CID000002337
Drugaprindine

SCN10A SCN4A SCN7A

1.37e-0538283CID000002218
DrugFlunarizine

CACNA1H CACNA1G

1.46e-055282DB04841
DrugS-ropivacaine

SCN10A SCN4A SCN7A

1.60e-0540283CID000071273
Drugamlodipine

CACNA1S CACNA1H CACNA1G SLC16A2

1.65e-05126284CID000002162
Drugpimozide

CACNA1S CACNA1H CACNA1G TPCN1

1.70e-05127284CID000016362
DrugAPETx1, Anthopleura elegantissima

SCN10A SCN4A

2.18e-056282ctd:C475726
Drug3,4-dihydroquinazoline

CACNA1H CACNA1G

2.18e-056282CID000583065
Druglanthanum

CACNA1S CACNA1H CACNA1G TPCN1

2.23e-05136284CID000023926
Drugspiradoline

SCN10A SCN4A SCN7A

2.44e-0546283CID000005620
DrugDantrolene-13C3

CACNA1S CACNA1H CACNA1G TPCN1

2.87e-05145284CID000002951
Drugnimodipine

CACNA1S CACNA1H CACNA1G TPCN1

2.87e-05145284CID000004497
Drugnicardipine

CACNA1S CACNA1H CACNA1G TPCN1

2.87e-05145284CID000004473
Drugindoxacarb

SCN10A SCN4A SCN7A

2.95e-0549283CID000107720
DrugIsradipine

CACNA1S CACNA1H

3.05e-057282DB00270
DrugLY215840

CACNA1H CACNA1G

3.05e-057282CID000132049
DrugKW-3049

CACNA1S CACNA1H CACNA1G

3.14e-0550283CID000002324
DrugBay K 8644

CACNA1S CACNA1H CACNA1G TPCN1

3.28e-05150284CID000002303
DrugAC1NSN3X

SCN10A SCN4A SCN7A

3.96e-0554283CID005366189
DrugNitrendipine

CACNA1S CACNA1H

4.07e-058282DB01054
DrugCocaine

SCN10A SCN5A

4.07e-058282DB00907
DrugNifedipine

CACNA1S CACNA1H

4.07e-058282DB01115
Drugamiodarone

SCN10A SCN4A SCN5A SCN7A

4.22e-05160284CID000002156
Drugtriamterene

SCN10A SCN4A SCN7A

4.91e-0558283CID000005546
Drugfelodipine

CACNA1S CACNA1H CACNA1G TPCN1

5.22e-05169284CID000003333
DrugMexiletine

SCN10A SCN5A

5.22e-059282ctd:D008801
Drugcyclaine

SCN10A SCN5A

5.22e-059282CID000010770
DrugLandel

CACNA1S CACNA1H

5.22e-059282CID000163838
DrugD-myo-inositol-1,4,5-triphosphate

CACNA1S CACNA1H CACNA1G UCN3 XPOT TPCN1

5.54e-05568286CID000000806
DrugIAA-94

CACNA1S CACNA1H CACNA1G

5.72e-0561283CID000003667
Drugfenfluramine

SCN10A DSEL SCN4A SCN7A

6.39e-05178284CID000003337
Drugsaxitoxin

SCN10A SCN4A SCN7A

6.91e-0565283CID000037165
Drugresiniferatoxin

SCN10A SCN4A SCN7A

7.24e-0566283CID000104826
DrugFelodipine

CACNA1S CACNA1H

7.97e-0511282DB01023
DrugEBNs

CACNA1H CACNA1G

7.97e-0511282CID000150695
Drugnorketamine

POSTN DSEL

7.97e-0511282CID000123767
Drugprocainamide

SCN10A SCN4A SCN5A SCN7A

8.22e-05190284CID000004913
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN10A SCN4A SCN5A SCN7A

1.16e-1010274DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN10A SCN4A SCN5A SCN7A

1.16e-1010274DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN10A SCN4A SCN5A SCN7A

2.74e-1012274DOID:0060170 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SCN10A SLC13A2 SCN4A SCN5A SCN7A

3.54e-07163275DOID:1826 (implicated_via_orthology)
DiseaseHYPOKALEMIC PERIODIC PARALYSIS, TYPE 1

CACNA1S SCN4A

8.06e-072272170400
DiseaseHypokalemic periodic paralysis, type 1

CACNA1S SCN4A

8.06e-072272cv:C3714580
DiseaseHypokalemic periodic paralysis

CACNA1S SCN4A

8.06e-072272cv:C0238358
Diseasebone structure disease (implicated_via_orthology)

POSTN QRFPR

8.06e-072272DOID:0080010 (implicated_via_orthology)
DiseaseHypokalemic periodic paralysis type 1

CACNA1S SCN4A

2.42e-063272C3714580
DiseaseBrugada ECG Pattern

SCN10A SCN5A

4.83e-064272C1721096
DiseaseHypokalemic periodic paralysis

CACNA1S SCN4A

4.83e-064272C0238358
Diseaseelectrocardiography, PR interval

SCN10A SCN5A

1.69e-057272EFO_0004327, EFO_0004462
Diseasehypokalemic periodic paralysis (implicated_via_orthology)

CACNA1S SCN4A

2.25e-058272DOID:14452 (implicated_via_orthology)
Diseasesupraventricular ectopy

SCN10A SCN5A

2.89e-059272EFO_0009277
DiseaseCongenital myopathy (disorder)

CACNA1S SCN4A

5.29e-0512272C0270960
DiseaseBrugada Syndrome 1

SCN10A SCN5A

6.25e-0513272C4551804
DiseaseT wave morphology measurement

SCN10A SCN5A

7.29e-0514272EFO_0008398
DiseaseP wave duration

SCN10A SCN5A

8.40e-0515272EFO_0005094
DiseaseRomano-Ward Syndrome

SCN10A SCN5A

9.60e-0516272C0035828
DiseaseBrugada syndrome

SCN10A SCN5A

1.37e-0419272MONDO_0015263
DiseaseBrugada Syndrome (disorder)

SCN10A SCN5A

2.20e-0424272C1142166
Diseasecardiovascular age measurement

SCN10A SCN5A

3.22e-0429272EFO_0803380
Diseasemigraine disorder, glucose measurement

CACNA1H KDM4A

3.69e-0431272EFO_0004468, MONDO_0005277
Diseaseheart function measurement

SCN10A SCN5A

4.44e-0434272EFO_0004311
DiseaseQRS complex, QRS duration

SCN10A SCN5A

7.79e-0445272EFO_0005054, EFO_0005055

Protein segments in the cluster

PeptideGeneStartEntry
LLIFMMLLAPIIHAF

ADGRL3

6

Q9HAR2
AVILFFVPLMHQRMF

SLC16A2

491

P36021
ILFLLPLMVMLILYS

QRFPR

221

Q96P65
PHLQLMLFLLFLLMY

OR10H5

21

Q8NGA6
PHLQLMLFLLFLLMY

OR10H2

21

O60403
MMPLLSLIFSALFIL

DNAJC16

536

Q9Y2G8
AFLRHKMTLISPLML

KDM4A

236

O75164
MIAFLLTSVLMIPHA

OC90

1

Q02509
LLMLFIFIFSILGMH

CACNA1G

871

O43497
KAMLPLFHIALLVLF

CACNA1S

191

Q13698
VVDLLFLLGMPFMIH

MCHR1

156

Q99705
IAMAMSLLFIILLRF

SLC44A2

241

Q8IWA5
LLMLFIFIFSILGMH

CACNA1H

921

O95180
LAVTALFPLILFPMM

SLC13A2

56

Q13183
MALMFTGHLLFLALL

DSEL

1

Q8IZU8
PHLQLMLFLLFLLMY

OR10H1

21

Q9Y4A9
LMFMHLSPILLLSLN

MT-ND4

436

P03905
MVELMFPLLLLLLPF

RDH11

1

Q8TC12
LLFALMMSLPALFNI

SCN4A

1471

P35499
FQMLHLVFILPSLML

SLC22A10

16

Q63ZE4
LLFALMMSLPALFNI

SCN5A

1646

Q14524
MFMLAILLTFFHPFL

SLC43A3

461

Q8NBI5
GRVLLVLMFMTLLHF

SURF4

161

O15260
LLFALMMSLPALFNI

SCN10A

1596

Q9Y5Y9
PFMDILLLLLFFMII

TPCN1

231

Q9ULQ1
LQQMFMPLLHAIFEV

XPOT

761

O43592
FHNLMLPLMLSLPAL

SCN7A

1366

Q01118
MLMPVHFLLLLLLLL

UCN3

1

Q969E3
MIPFLPMFSLLLLLI

POSTN

1

Q15063