Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	regulation of double-strand break repair via homologous recombination	WAS PELI1 ACTL6A TEX15 PARP1 RUVBL1 POLQ	1.78e-06	83	143	7	GO:0010569
GeneOntologyBiologicalProcess	positive regulation of double-strand break repair via homologous recombination	WAS PELI1 ACTL6A PARP1 RUVBL1	1.30e-05	44	143	5	GO:1905168
GeneOntologyBiologicalProcess	double-strand break repair via homologous recombination	WAS PELI1 ACTL6A TEX15 PARP1 RUVBL1 MCM9 POLQ	5.11e-05	188	143	8	GO:0000724
GeneOntologyBiologicalProcess	recombinational repair	WAS PELI1 ACTL6A TEX15 PARP1 RUVBL1 MCM9 POLQ	6.38e-05	194	143	8	GO:0000725
GeneOntologyBiologicalProcess	regulation of double-strand break repair	WAS PELI1 ACTL6A TEX15 PARP1 RUVBL1 POLQ	7.22e-05	146	143	7	GO:2000779
GeneOntologyBiologicalProcess	regulation of DNA recombination	WAS PELI1 ACTL6A TEX15 PARP1 RUVBL1 POLQ	8.56e-05	150	143	7	GO:0000018
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	IL12RB1 FLNC PCDHGC5 PCDHGC4 KDM5A WDR33 PCDHGA9 PCLO GARS1 SANBR MECP2 TUFM PARP1 NEK2 MLIP MDN1 AP2B1 NAV2 BOD1L1 USPL1 SPAG17 POLQ PCDHGA8 CFAP46	1.08e-08	1442	148	24	35575683
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	JCAD ARHGEF28 SASH1 KDM5A SYDE1 TAB3 CEP170 MDN1 TIAM1 NAV2 MAP3K9 MAP3K10 RAB11FIP5 COBL BOD1L1 USP54 DCP1A NOS1AP	3.11e-08	861	148	18	36931259
Pubmed	A protein interaction landscape of breast cancer.	DNAJB12 TRIM25 ZNF148 ANK3 GARS1 ACTL6A CEP170 PARP1 MDN1 AP2B1 MCM9 MKI67 NAV2 PIP4K2C AMOTL2	9.77e-08	634	148	15	34591612
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	ZNF148 ANK3 WDR33 ACTL6A ANKHD1 TUFM TAB3 CEP170 RUVBL1 RPRD2 BOD1L1 AMOTL2 HCFC1 DCP1A	1.08e-07	549	148	14	38280479
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	IL12RB1 FLNC TRIM25 ANK3 PCLO WDR37 CIT TF ELFN2 MECP2 OPA1 TUFM SLC4A1 CEP170 DIP2A PARP1 KIDINS220 MLIP AP2B1 USP54 PIP4K2C ALDH7A1	1.88e-07	1431	148	22	37142655
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF148 KDM5A ACTL6A ANKHD1 WDR37 TF MECP2 OPA1 TUFM SLC4A1 CEP170 TUBGCP6 RAB11FIP5 STK39 USP54 PIP4K2C NOS1AP	5.89e-06	1116	148	17	31753913
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	FLNC TRIM25 WDR33 KIDINS220 RUVBL1 RAB11FIP5 BOD1L1 HCFC1 XPOT	8.47e-06	313	148	9	38270169
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	TUT1 ACTL6A MECP2 SYDE1 WDR74 ZNF16 MDN1 VILL USP42 SKOR2 RPRD2 POC5 USP48	8.55e-06	689	148	13	36543142
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	FLNC WDR33 CEP170 PARP1 RUVBL1 MKI67 RPRD2 BOD1L1 HCFC1 DCP1A	8.82e-06	399	148	10	35987950
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ANK3 ACTL6A OPA1 WDR74 DIP2A MDN1 NBEAL2 NAV2 COBL HCFC1 XPOT	1.00e-05	497	148	11	36774506
Pubmed	The TIP60 Complex Is a Conserved Coactivator of HIF1A.	ACTL6A TUFM RUVBL1 STK39 HCFC1 XPOT	1.31e-05	120	148	6	27320910
Pubmed	Interactome of Aiolos/Ikaros Reveals Combination Rationale of Cereblon Modulators with HDAC Inhibitors in DLBCL.	IKZF2 IKZF1 ACTL6A PARP1 RUVBL1 MKI67	1.51e-05	123	148	6	35583604
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SASH1 SANBR ANKHD1 WDR37 TUBGCP6 ARHGAP31 NBEAL2 NAV2 RAB11FIP5 RPRD2 AMOTL2	1.78e-05	529	148	11	14621295
Pubmed	Helios deficiency has minimal impact on T cell development and function.	IKZF2 IKZF1	1.80e-05	2	148	2	19620299
Pubmed	Poly(ADP-ribose)polymerase 1 stimulates the AP-site cleavage activity of tyrosyl-DNA phosphodiesterase 1.	PARP1 TDP1	1.80e-05	2	148	2	26181362
Pubmed	COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia.	IKZF1 COBL	1.80e-05	2	148	2	27419633
Pubmed	Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains.	MAP3K9 MAP3K10	1.80e-05	2	148	2	8477742
Pubmed	Complete nucleotide sequence, expression, and chromosomal localisation of human mixed-lineage kinase 2.	MAP3K9 MAP3K10	1.80e-05	2	148	2	8536694
Pubmed	Ankyrin-G promotes cyclic nucleotide-gated channel transport to rod photoreceptor sensory cilia.	ANK3 CNGB1	1.80e-05	2	148	2	19299621
Pubmed	TDP1 and PARP1 deficiency are cytotoxic to rhabdomyosarcoma cells.	PARP1 TDP1	1.80e-05	2	148	2	23913164
Pubmed	Poly(ADP-ribosyl)ation of Methyl CpG Binding Domain Protein 2 Regulates Chromatin Structure.	MECP2 PARP1	1.80e-05	2	148	2	26772194
Pubmed	VEGFR-3 signaling is regulated by a G-protein activator, activator of G-protein signaling 8, in lymphatic endothelial cells.	FLT4 FNDC1	1.80e-05	2	148	2	29649427
Pubmed	The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis.	MAP3K9 MAP3K10	1.80e-05	2	148	2	11416147
Pubmed	Recurrent deletions in clonal hematopoiesis are driven by microhomology-mediated end joining.	PARP1 POLQ	1.80e-05	2	148	2	33911081
Pubmed	Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytes.	IKZF2 IKZF1	1.80e-05	2	148	2	17681952
Pubmed	[Expression characteristics of isoforms of Ikaros and Helios in patients with leukemia and their mechanism].	IKZF2 IKZF1	1.80e-05	2	148	2	22931634
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TRIM25 ZNF148 GARS1 GBE1 IKZF1 ACTL6A CIT MECP2 CEP170 WDR74 PARP1 AP2B1 MKI67 HNRNPLL HCFC1 XPOT	2.05e-05	1103	148	16	34189442
Pubmed	Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer.	ANK3 MKI67 HCFC1	2.09e-05	13	148	3	15931389
Pubmed	The functional interactome landscape of the human histone deacetylase family.	IKZF2 KDM5A WDR33 IKZF1 ACTL6A WDR74 MDN1 MKI67	3.56e-05	289	148	8	23752268
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	SASH1 ANK3 RPS6KA1 DIP2A KIDINS220 TIAM1 ARHGAP31 RAB11FIP5 PIP5K1A	3.67e-05	377	148	9	38117590
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	ZNF148 WDR33 MECP2 TUFM CEP170 AP2B1 RAB11FIP5 RPRD2 PIP4K2C DCP1A	3.71e-05	472	148	10	38943005
Pubmed	Defining the membrane proteome of NK cells.	DNAJB12 CIT OPA1 TUFM TUBGCP6 PARP1 KIDINS220 MDN1 AP2B1 PIK3CG NBEAL2 GZMH MKI67 HNRNPLL HCFC1 DCP1A	4.07e-05	1168	148	16	19946888
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	FLNC TRIM25 ANK3 PCLO GARS1 PIR TUFM PARP1 MDN1 RUVBL1 AP2B1 SPAG17 XPOT	4.43e-05	807	148	13	30575818
Pubmed	An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.	SALL3 ACTL6A PARP1 AMOTL2 HCFC1	4.52e-05	91	148	5	20362542
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	ZNF148 KDM5A GARS1 IKZF1 ACTL6A TF OPA1 TUFM WDR74 PARP1 MDN1 RUVBL1 USP42 MKI67 PIP4K2C HCFC1 XPOT	4.88e-05	1318	148	17	30463901
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	ACTL6A MDN1 AP2B1 MCM9 RPRD2 POLQ HCFC1	4.90e-05	222	148	7	37071664
Pubmed	Minor spliceosome inactivation causes microcephaly, owing to cell cycle defects and death of self-amplifying radial glial cells.	CIT PARP1 MKI67	4.91e-05	17	148	3	30093551
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	TRIM25 WAS WDR33 IKZF1 ACTL6A WDR37 TUFM CEP170 WDR74 RUVBL1 AP2B1 HCFC1	4.93e-05	701	148	12	30196744
Pubmed	Mice lacking both mixed-lineage kinase genes Mlk1 and Mlk2 retain a wild type phenotype.	MAP3K9 MAP3K10	5.38e-05	3	148	2	18414056
Pubmed	TDP1 is Critical for the Repair of DNA Breaks Induced by Sapacitabine, a Nucleoside also Targeting ATM- and BRCA-Deficient Tumors.	PARP1 TDP1	5.38e-05	3	148	2	28802254
Pubmed	Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors.	IKZF2 IKZF1	5.38e-05	3	148	2	9560339
Pubmed	Analysis of Ikaros family splicing variants in human hematopoietic lineages.	IKZF2 IKZF1	5.38e-05	3	148	2	20432734
Pubmed	Evidence of a structural and functional ammonium transporter RhBG·anion exchanger 1·ankyrin-G complex in kidney epithelial cells.	ANK3 SLC4A1	5.38e-05	3	148	2	25616663
Pubmed	L1 coupling to ankyrin and the spectrin-actin cytoskeleton modulates ethanol inhibition of L1 adhesion and ethanol teratogenesis.	ANK3 RPS6KA1	5.38e-05	3	148	2	29109170
Pubmed	Identification and characterization of SPRK, a novel src-homology 3 domain-containing proline-rich kinase with serine/threonine kinase activity.	MAP3K9 MAP3K10	5.38e-05	3	148	2	8195146
Pubmed	Aberrant Ikaros, Aiolos, and Helios expression in Hodgkin and non-Hodgkin lymphoma.	IKZF2 IKZF1	5.38e-05	3	148	2	18332232
Pubmed	Cloning and characterization of mCRIP2, a mouse LIM-only protein that interacts with PDZ domain IV of PTP-BL.	CRIP1 CRIP2	5.38e-05	3	148	2	12839623
Pubmed	Synergistic interaction of two independent genetic loci causes extreme elevation of serum IgA in mice.	CRIP1 CRIP2	5.38e-05	3	148	2	15175647
Pubmed	The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.	ASXL1 HCFC1	5.38e-05	3	148	2	21642991
Pubmed	Overexpression of novel short isoforms of Helios in a patient with T-cell acute lymphoblastic leukemia.	IKZF2 IKZF1	5.38e-05	3	148	2	11937265
Pubmed	Ankyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migration.	ANK3 TIAM1	5.38e-05	3	148	2	10893266
Pubmed	Novel interactions of ankyrins-G at the costameres: the muscle-specific Obscurin/Titin-Binding-related Domain (OTBD) binds plectin and filamin C.	FLNC ANK3	5.38e-05	3	148	2	21223964
Pubmed	Expression patterns of Ikaros family members during positive selection and lineage commitment of human thymocytes.	IKZF2 IKZF1	5.38e-05	3	148	2	27502439
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	FLNC KDM5A WDR33 ACTL6A MECP2 OPA1 TUFM IWS1 CEP170 PARP1 KIDINS220 RUVBL1 AP2B1 USP42 HNRNPLL	6.27e-05	1082	148	15	38697112
Pubmed	Phosphoinositide 3-Kinase (PI3K) Subunit p110δ Is Essential for Trophoblast Cell Differentiation and Placental Development in Mouse.	PIK3CG MKI67 MMP12	6.96e-05	19	148	3	27306493
Pubmed	Ikaros promotes early-born neuronal fates in the cerebral cortex.	IKZF2 IKZF1 MKI67	6.96e-05	19	148	3	23382203
Pubmed	Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.	SALL3 IKZF1 BCL6B	6.96e-05	19	148	3	30385546
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	PCLO GARS1 ZNF831 TUFM DIP2A MDN1 GZMH PCIF1 MAP3K9 BOD1L1 AMOTL2 SP7	7.84e-05	736	148	12	29676528
Pubmed	Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.	ITFG2 IKZF1 TUT1 MECP2 ZUP1 MLIP VILL MCM9 NAV2 AMOTL2 HNRNPLL DCP1A	8.46e-05	742	148	12	26871637
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	SASH1 ANK3 WDR37 OPA1 KIDINS220 RAB11FIP5 PIP5K1A COBL NOS1AP	8.54e-05	421	148	9	36976175
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	TRIM25 PARP1 MDN1 RUVBL1 BOD1L1 USP48 HNRNPLL HCFC1	9.38e-05	332	148	8	32786267
Pubmed	Differential expression of the immunosuppressive enzyme IL4I1 in human induced Aiolos+, but not natural Helios+, FOXP3+ Treg cells.	IKZF2 IL4I1	1.07e-04	4	148	2	25446972
Pubmed	Actin-related proteins.	ACTL6A ACTL7B	1.07e-04	4	148	2	10611965
Pubmed	Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of β-catenin.	ANK3 MKI67	1.07e-04	4	148	2	24821222
Pubmed	Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair.	E4F1 PARP1	1.07e-04	4	148	2	33692124
Pubmed	The genetics of human infertility by functional interrogation of SNPs in mice.	TEX15 SMC1B	1.07e-04	4	148	2	26240362
Pubmed	PARP1 Promotes Heart Regeneration and Cardiomyocyte Proliferation.	PARP1 MKI67	1.07e-04	4	148	2	38481797
Pubmed	PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism.	PIP5K1A PIP4K2C	1.07e-04	4	148	2	31091439
Pubmed	The origin of a developmentally regulated Igh replicon is located near the border of regulatory domains for Igh replication and expression.	CRIP1 CRIP2	1.07e-04	4	148	2	12370427
Pubmed	A targeted mouse Brca1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage.	PARP1 MKI67	1.07e-04	4	148	2	11420664
Pubmed	Biochemical and cellular characterization of transcription factors binding to the hyperconserved core promoter-associated M4 motif.	IKZF1 HCFC1	1.07e-04	4	148	2	27576892
Pubmed	Pharmacodynamic genes do not influence risk of neutropenia in cancer patients treated with moderately high-dose irinotecan.	PARP1 TDP1	1.07e-04	4	148	2	19604089
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	JCAD ANK3 PCLO SANBR CIT ELFN2 OPA1 CRIP2 TAB3 CEP170 RUVBL1 SPHKAP MAP3K10 HNRNPLL NOS1AP	1.11e-04	1139	148	15	36417873
Pubmed	Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos.	ACTL6A WDR74 USPL1 HCFC1	1.12e-04	58	148	4	27869233
Pubmed	Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells.	IKZF2 ZNF148 IKZF1 ACTL6A TUFM PARP1	1.19e-04	178	148	6	27637333
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	JCAD ANK3 KDM5A CIT TF DIP2A PARP1 TIAM1 AP2B1 MAP3K10 ASTN2 USP54 AMOTL2 USPL1 WDR17 XPOT	1.24e-04	1285	148	16	35914814
Pubmed	Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.	USP42 USP54 USP48	1.26e-04	23	148	3	14715245
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	ANK3 TAB3 KIDINS220 FAM193A MKI67 RAB11FIP5 USP54	1.41e-04	263	148	7	34702444
Pubmed	Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.	WDR33 ACTL6A PARP1 MDN1 RUVBL1	1.43e-04	116	148	5	21549307
Pubmed	Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions.	MECP2 HOXA3 PIP5K1A HCFC1	1.74e-04	65	148	4	17567994
Pubmed	Paternal deletion of Meg1/Grb10 DMR causes maternalization of the Meg1/Grb10 cluster in mouse proximal Chromosome 11 leading to severe pre- and postnatal growth retardation.	IKZF1 COBL	1.78e-04	5	148	2	19174477
Pubmed	In vitro evaluation of pan-PI3-kinase inhibitor SF1126 in trastuzumab-sensitive and trastuzumab-resistant HER2-over-expressing breast cancer cells.	PARP1 PIK3CG	1.78e-04	5	148	2	19636556
Pubmed	Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities.	IKZF2 IKZF1	1.78e-04	5	148	2	10978333
Pubmed	Promising molecular targets in ovarian cancer.	PARP1 PIK3CG	1.78e-04	5	148	2	19553815
Pubmed	The Tec Kinase Itk Integrates Naïve T Cell Migration and In Vivo Homeostasis.	TIAM1 PIK3CG	1.78e-04	5	148	2	34566971
Pubmed	A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs.	TUT1 PIP5K1A	1.78e-04	5	148	2	18288197
Pubmed	Irinotecan pharmacogenetics: influence of pharmacodynamic genes.	PARP1 TDP1	1.78e-04	5	148	2	18347181
Pubmed	Kinetics of endogenous mouse FEN1 in base excision repair.	PARP1 MKI67	1.78e-04	5	148	2	22810208
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TRIM25 ZNF148 ANKHD1 CEP170 PARP1 FAM193A RUVBL1 AP2B1 MKI67 RPRD2 BOD1L1 HCFC1 DCP1A	1.89e-04	934	148	13	33916271
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	IFT22 ZNF148 TRIM41 GARS1 TUT1 ACTL6A ANKHD1 OPA1 TUFM PARP1 RUVBL1 AP2B1 PIP5K1A HNRNPLL HCFC1 ALDH7A1	1.91e-04	1335	148	16	29229926
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHGC5 PCDHGC4 PCDHGA9 PCDHGA8	2.08e-04	68	148	4	11230163
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	MECP2 PARP1 RUVBL1 MKI67 RPRD2 BOD1L1 HCFC1	2.21e-04	283	148	7	30585729
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FLNC TRIM25 GARS1 ACTL6A ANKHD1 TUFM WDR74 PARP1 MDN1 RUVBL1 AP2B1 MKI67 PIP4K2C ALDH7A1 DCP1A XPOT	2.22e-04	1353	148	16	29467282
Pubmed	Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.	FLNC TUBGCP6 TIAM1 USP54 HCFC1	2.27e-04	128	148	5	25332235
Pubmed	NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.	IKZF2 IKZF1 PARP1 MDN1 HCFC1	2.35e-04	129	148	5	23022380
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	IKZF2 IKZF1 TUT1 E4F1 CRIP3 CRIP2 NKX1-2 ARNT2 MKI67 DCP1A SP7	2.40e-04	709	148	11	22988430
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	FLNC GARS1 ACTL6A PIR OPA1 TUFM CRIP2 IWS1 EZHIP CEP170 PARP1 RUVBL1 PIP5K1A STK39 HCFC1 ALDH7A1	2.49e-04	1367	148	16	32687490
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHGC5 PCDHGC4 PCDHGA9 PCDHGA8	2.59e-04	72	148	4	10380929
Pubmed	NIMA-related kinases: isolation and characterization of murine nek3 and nek4 cDNAs, and chromosomal localization of nek1, nek2 and nek3.	PARP1 NEK2	2.67e-04	6	148	2	10393247
Pubmed	CKIalpha is associated with and phosphorylates star-PAP and is also required for expression of select star-PAP target messenger RNAs.	TUT1 PIP5K1A	2.67e-04	6	148	2	18305108
Interaction	PPIA interactions	ASXL1 FLNC TRIM25 ZNF148 SALL3 ANK3 WDR33 SH2D3C IKZF1 PIR CIT MECP2 TUFM CRIP1 CEP170 AP2B1 MKI67 RAB11FIP5 RPRD2 PIP4K2C USP48 HCFC1 ALDH7A1 DCP1A	2.78e-08	888	147	24	int:PPIA
Interaction	SIN3A interactions	IKZF2 TRIM25 IKZF1 ACTL6A PIR CIT MECP2 BCL6B PARP1 ARNT2 BOD1L1 HCFC1 SP7	4.43e-06	380	147	13	int:SIN3A
Interaction	YWHAH interactions	JCAD LCA5 ARHGEF28 SASH1 KDM5A RPS6KA1 WDR37 SYDE1 TAB3 CEP170 TIAM1 NAV2 MAP3K9 MAP3K10 RAB11FIP5 COBL BOD1L1 USP54 AMOTL2 USP48 ALDH7A1 DCP1A NOS1AP	4.95e-06	1102	147	23	int:YWHAH
Interaction	ATG16L1 interactions	TRIM25 ARHGEF28 WAS ANK3 WDR33 IKZF1 ACTL6A WDR37 TF ELFN2 SYDE1 TUFM CEP170 WDR74 DIP2A PARP1 FAM193A RUVBL1 AP2B1 RAB11FIP5 POC5 USP54 HCFC1	1.16e-05	1161	147	23	int:ATG16L1
Interaction	YWHAG interactions	JCAD LCA5 ARHGEF28 SASH1 RPS6KA1 SH2D3C WDR37 SYDE1 TAB3 CEP170 MDN1 TIAM1 NAV2 MAP3K9 MAP3K10 RAB11FIP5 COBL BOD1L1 USP54 AMOTL2 USP48 ALDH7A1 DCP1A NOS1AP	1.19e-05	1248	147	24	int:YWHAG
Interaction	MORF4L2 interactions	KDM5A TRIM41 IKZF1 ACTL6A CIT MECP2 RUVBL1 AMOTL2	3.29e-05	168	147	8	int:MORF4L2
Interaction	CAMK2D interactions	ASXL1 SH2D3C MECP2 CEP170 TIAM1 PIP5K1A BOD1L1 USP48 HCFC1	3.75e-05	222	147	9	int:CAMK2D
Cytoband	5q31	PCDHGC5 PCDHGC4 PCDHGA9 PCDHGA8 ALDH7A1	3.75e-05	115	148	5	5q31
GeneFamily	Ubiquitin specific peptidases	USP42 USP54 USPL1 USP48	2.22e-04	56	96	4	366
GeneFamily	Clustered protocadherins	PCDHGC5 PCDHGC4 PCDHGA9 PCDHGA8	3.72e-04	64	96	4	20
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	IKZF1 ELFN2 NEK2 PCIF1 MKI67 HCFC1	4.08e-04	181	96	6	694
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	IKZF2 ZNF148 SALL3 ZNF208 IKZF1 E4F1 ZUP1 ZNF10 BCL6B ZNF16 ZNF669 SP7	4.13e-04	718	96	12	28
GeneFamily	INO80 complex \|SRCAP complex	ACTL6A RUVBL1	9.80e-04	9	96	2	1329
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PCLO PARP1	2.80e-03	15	96	2	26
GeneFamily	INO80 complex \|SRCAP complex	ACTL6A RUVBL1	2.80e-03	15	96	2	595
GeneFamily	LIM domain containing	CRIP3 CRIP1 CRIP2	3.80e-03	59	96	3	1218
Coexpression	GSE8621_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN	ASXL1 TRIM25 IKZF1 CHRNA2 OPA1 IWS1 PARP1 TIAM1 USP42	1.95e-06	199	147	9	M6987
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	ASXL1 ZNF148 SASH1 KDM5A GBE1 MGLL WDR37 MECP2 OPA1 CEP170 KIDINS220 FAM193A MDN1 TIAM1 ARNT2 PIP5K1A STK39	6.61e-06	856	147	17	M4500
Coexpression	GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_DN	IKZF2 SANBR PKHD1L1 TF CRIP2 DIP2A ARNT2 COBL	1.80e-05	200	147	8	M4346
ToppCell	Endothelial-B-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	FLNC FLT4 GARS1 PKHD1L1 BCL6B SEMA3D CDH22 MLIP	9.66e-08	168	148	8	4977c3837fbb1f36c89fddd5764e37290ac25ad8
ToppCell	Endothelial-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	FLNC FLT4 GARS1 PKHD1L1 CRIP2 BCL6B SEMA3D CDH22	1.11e-07	171	148	8	07ff7059071da83da1d8f266a586573920d75b58
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	IL12RB1 IKZF2 SASH1 KDM5A PELI1 NEK2 TIAM1 ZNF669	1.71e-07	181	148	8	b193f3606554adc55c5906219d114288bb1f978a
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLT4 SASH1 SH2D3C PKHD1L1 SEMA3D CDH22 MLIP RAB11FIP5	2.48e-07	190	148	8	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNC FLT4 SASH1 SH2D3C PKHD1L1 CRIP2 BCL6B SEMA3D	2.91e-07	194	148	8	937ee85ffd50869b60f0f6e91017ab77e8b24c0b
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNC FLT4 SASH1 SH2D3C PKHD1L1 CRIP2 BCL6B SEMA3D	3.27e-07	197	148	8	407231542fa1ffd540dcb61435c0575e71f59725
ToppCell	5'-Adult-LymphNode-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JCAD FLT4 SASH1 SH2D3C PKHD1L1 CRIP2 BCL6B SEMA3D	3.40e-07	198	148	8	d7e15e61b6018e4c36461c9471ee29601929925c
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNC FLT4 SASH1 SH2D3C PKHD1L1 CRIP2 SEMA3D RAB11FIP5	3.40e-07	198	148	8	5d42f4fda2081ea3e9f62a00e7eea702e0d0be7d
ToppCell	5'-Adult-Appendix-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JCAD FLT4 SASH1 PKHD1L1 CRIP2 BCL6B SEMA3D ARHGAP31	3.40e-07	198	148	8	90e85fe7a0ab376a41666dfff6c0e95b7f1c9475
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNC FLT4 SASH1 PKHD1L1 CRIP2 BCL6B SEMA3D RAB11FIP5	3.40e-07	198	148	8	99d6a64f3410dae3019161feef20a8f06081a24b
ToppCell	5'-Adult-SmallIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JCAD FLT4 SASH1 SH2D3C PKHD1L1 CRIP2 BCL6B ARHGAP31	3.67e-07	200	148	8	2554b77edfe3d378296b0b25625caacbfb1c0e76
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNC FLT4 PKHD1L1 CHRNA2 SEMA3D RAB11FIP5 WDR17	1.15e-06	161	148	7	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNC FLT4 PKHD1L1 CHRNA2 SEMA3D RAB11FIP5 WDR17	1.15e-06	161	148	7	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNC FLT4 PKHD1L1 CHRNA2 SEMA3D RAB11FIP5 WDR17	1.15e-06	161	148	7	cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNC FLT4 PKHD1L1 CHRNA2 SEMA3D RAB11FIP5 WDR17	1.20e-06	162	148	7	96c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPST2 SASH1 PCDHGA9 SH2D3C CRIP2 HOXA3 BCL6B	1.79e-06	172	148	7	e359c59631f6a262429b6896a409f2ffbd4f6a76
ToppCell	Endothelial-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	JCAD FLNC FLT4 PKHD1L1 FREM1 BCL6B SEMA3D	1.79e-06	172	148	7	8a527dff06d841a86c7eb04a1dd9630787294da4
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNC FLT4 SASH1 SH2D3C PKHD1L1 CRIP2 CDH22	1.86e-06	173	148	7	7dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 SH2D3C ZNF831 PKHD1L1 SEMA3D CDH22 SPHKAP	2.17e-06	177	148	7	c274fbdc141855ff4581d437d4997c64cc193278
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 SH2D3C ZNF831 PKHD1L1 SEMA3D CDH22 SPHKAP	2.17e-06	177	148	7	f5e6df5cafd003bbfbb3b634ee58d0b1e2be5cc7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 SH2D3C ZNF831 PKHD1L1 SEMA3D CDH22 SPHKAP	2.17e-06	177	148	7	c8a51e480b978dc0ded85583261f2c892e085be8
ToppCell	5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TPST2 FLNC FLT4 SH2D3C PKHD1L1 CRIP2 SEMA3D	2.25e-06	178	148	7	4b3ea0921bc598ebb9f63780ecdf8ad4349f3666
ToppCell	5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JCAD FLT4 SH2D3C PKHD1L1 CRIP2 BCL6B SEMA3D	2.34e-06	179	148	7	9fd9b136ecbcbd4e4f0d5875ede98d8d48608afb
ToppCell	ILEUM-non-inflamed-(7)_Lymphatics\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	JCAD FLT4 SASH1 PCLO GARS1 CRIP2 SEMA3D	2.34e-06	179	148	7	99777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNC FLT4 SASH1 PKHD1L1 SEMA3D CDH22 SPHKAP	2.52e-06	181	148	7	e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell	3'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TPST2 FLT4 SH2D3C PKHD1L1 CRIP2 CEP170 SEMA3D	2.61e-06	182	148	7	82d6f72649c7dd4d64a84a9795edebdef2f285d6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IKZF2 ARHGEF28 GBE1 MLIP PIK3CG HNRNPLL PDZRN4	2.81e-06	184	148	7	9a185e6ea86bbfbb48bfe88650a8c05ceba78d7f
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF28 ANK3 SPHKAP ADAMTS17 NAV2 USP54 NOS1AP	2.91e-06	185	148	7	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	ILEUM-inflamed-(7)_Lymphatics\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FLT4 SASH1 PCLO GARS1 CRIP2 BCL6B SEMA3D	2.91e-06	185	148	7	d711dd2e91cfee723dae1ccb2b910b8cf3becc3b
ToppCell	15-Distal-Immune-Hematopoietic,_T_Cells\|Distal / Age, Tissue, Lineage and Cell class	IKZF2 WAS RPS6KA1 IKZF1 ZNF831 PIK3CG IL4I1	2.91e-06	185	148	7	481e3d3b63f2e5b4783088523c3cf70a461aed27
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TPST2 SALL3 FREM1 ARNT2 ADAMTS17 STK39 NOS1AP	3.23e-06	188	148	7	bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TPST2 SALL3 FREM1 ARNT2 ADAMTS17 STK39 NOS1AP	3.23e-06	188	148	7	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLNC FLT4 SH2D3C PKHD1L1 BCL6B SEMA3D CDH22	3.23e-06	188	148	7	26915db8863f4115b46a81982e187322e21600fd
ToppCell	5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNC FLT4 SASH1 PKHD1L1 CRIP2 SEMA3D CFAP46	3.23e-06	188	148	7	524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MGLL NBEAL2 NAV2 MAP3K9 COBL STK39 NOS1AP	3.23e-06	188	148	7	43a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLNC FLT4 SH2D3C PKHD1L1 BCL6B SEMA3D CDH22	3.23e-06	188	148	7	3f76c0f912f8f023ea425be7f43593b3d7f967e3
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLNC FLT4 SH2D3C PKHD1L1 BCL6B SEMA3D CDH22	3.23e-06	188	148	7	61ee7b152745164293d8a44ef91ee2393efbdca5
ToppCell	5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNC FLT4 SASH1 PKHD1L1 CRIP2 SEMA3D CFAP46	3.23e-06	188	148	7	d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCell	droplet-Fat-SCAT-30m\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGLL CRIP2 SEMA3D FNDC1 MLIP COBL PRKG2	3.35e-06	189	148	7	8161910a19089f8cc5a3f1fda039f41a2488f04f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SASH1 FREM1 TIAM1 SPHKAP NAV2 ASTN2 PRKG2	3.35e-06	189	148	7	06c44746fa4f02e6e2b3b635cdf2d8dfef3754d3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SALL3 FREM1 ARNT2 ADAMTS17 NAV2 STK39 NOS1AP	3.35e-06	189	148	7	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SALL3 FREM1 ARNT2 ADAMTS17 NAV2 STK39 NOS1AP	3.35e-06	189	148	7	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	droplet-Fat-SCAT\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGLL CRIP2 SEMA3D FNDC1 MLIP COBL PRKG2	3.35e-06	189	148	7	264c59de2adb8bee5bb57633d79d530a8829617b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 SASH1 SH2D3C PKHD1L1 SEMA3D CDH22 SPHKAP	3.47e-06	190	148	7	876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SASH1 MGLL ARNT2 NAV2 ASTN2 STK39 NOS1AP	3.47e-06	190	148	7	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SASH1 MGLL ARNT2 NAV2 ASTN2 STK39 NOS1AP	3.47e-06	190	148	7	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 SASH1 SH2D3C PKHD1L1 SEMA3D CDH22 SPHKAP	3.47e-06	190	148	7	be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 SASH1 SH2D3C PKHD1L1 SEMA3D CDH22 SPHKAP	3.47e-06	190	148	7	09a8855901c3c9332dbaab3e40166485b696d0f1
ToppCell	5'-Adult-LymphNode-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLT4 SASH1 SH2D3C PKHD1L1 CRIP2 BCL6B SEMA3D	3.47e-06	190	148	7	6b704deeb44e1ffa10e604d0e5612b022f6cd9a6
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IFT22 NEK2 POC5 SPAG17 CCDC17 ODAD3 CFAP46	3.59e-06	191	148	7	e8d56e9f43943e9cc4dce83f2c234f19c2dd487d
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IFT22 NEK2 POC5 SPAG17 CCDC17 ODAD3 CFAP46	3.59e-06	191	148	7	52e8d7dfaf1ebb6df8bf3a1f4546af59faa67657
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SASH1 FREM1 TIAM1 SPHKAP NAV2 ASTN2 PRKG2	3.59e-06	191	148	7	de54dab85db70f847de75b3b6d7667a0e13b9bfb
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SASH1 FREM1 TIAM1 SPHKAP NAV2 ASTN2 PRKG2	3.59e-06	191	148	7	9c0ee270209b02043393416ecc9a81ddedfbb8b6
ToppCell	LAM-Endothelial-LymEndo\|LAM / Condition, Lineage and Cell class	JCAD FLNC FLT4 PKHD1L1 CRIP2 BCL6B SEMA3D	3.85e-06	193	148	7	68eadc91c2d89edd2412e86dfe134dd7c0ef6ee9
ToppCell	COPD-Endothelial\|COPD / Disease state, Lineage and Cell class	JCAD FLT4 SASH1 PKHD1L1 CRIP2 BCL6B SEMA3D	3.85e-06	193	148	7	093b28dcccb5841c995d0b33fae0efd6b88f97e0
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SASH1 FREM1 TIAM1 SPHKAP NAV2 ASTN2 PRKG2	3.85e-06	193	148	7	8b77625bf3c87d39767fb391d1beaca4ab02342b
ToppCell	critical-Lymphoid-NK\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PIR SYDE1 MLIP NAV2 GMPR TRPM1 AMOTL2	3.85e-06	193	148	7	6be11fef87af04ee7a3cc223882ccd4077caded9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 ANK3 PCLO ARNT2 COBL ASTN2 SPAG17	3.98e-06	194	148	7	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	3'-Adult-LymphNode-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TPST2 FLT4 SH2D3C PKHD1L1 CRIP2 BCL6B SEMA3D	4.26e-06	196	148	7	a2845436003e9adf34677eb81e78f8334ff01faa
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNC FLT4 SH2D3C PKHD1L1 SEMA3D CDH22 ARHGAP31	4.26e-06	196	148	7	09a7edf4a7defb7fe70d9777dd9500ee8421ff31
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNC FLT4 SH2D3C PKHD1L1 SEMA3D CDH22 ARHGAP31	4.26e-06	196	148	7	e50d2c66d5c5cd25fdfecdcc4c8506a1d0a85755
ToppCell	3'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TPST2 FLT4 SH2D3C PKHD1L1 CRIP2 BCL6B SEMA3D	4.26e-06	196	148	7	aa52f77f80c3fe23369347a34e0b3188b768a763
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IKZF1 ZNF831 CRIP1 NEK2 MKI67 MAP3K9 POLQ	4.40e-06	197	148	7	04aaf35ef4db6325b2b2b92e93272f1973764b78
ToppCell	nucseq-Endothelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	JCAD FLT4 SASH1 SH2D3C PKHD1L1 CRIP2 SEMA3D	4.40e-06	197	148	7	ebf9be068eaa658493fa7884fd19f34642922acb
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TEX15 PIR PKHD1L1 NEK2 MKI67 NAV2 POLQ	4.40e-06	197	148	7	76b61e60a757e58b465569538e632d6d9953e89a
ToppCell	LPS-antiTNF-Unknown\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CIT NEK2 MLIP MKI67 POLQ WDR17	4.67e-06	129	148	6	739b263296c28554967362060b154f7a95e1341d
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M\|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.	WDR37 CEP170 KIDINS220 AP2B1 BOD1L1 PCDHGA8 PDZRN4	4.70e-06	199	148	7	b2d7dea11207cca63d688f8051143850b29dbdf0
ToppCell	Biopsy_Other_PF-Endothelial-Lymphatic_Endothelial_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	FLNC FLT4 PKHD1L1 CRIP2 SEMA3D CDH22 RAB11FIP5	4.70e-06	199	148	7	aa80c77fe4f6a141c780c7d8ecfff5d5a1c3b845
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SASH1 FREM1 TIAM1 SPHKAP NAV2 ASTN2 PRKG2	4.86e-06	200	148	7	858421b91f5207b7934b5c219752cb9322a3da31
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLT4 SH2D3C PKHD1L1 CRIP2 SEMA3D CDH22 RAB11FIP5	4.86e-06	200	148	7	f99d0d3f51b4893fa7898c5b435494358a654cbd
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IKZF2 ARHGEF28 ANK3 PCLO COBL STK39 NOS1AP	4.86e-06	200	148	7	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	FLT4 SH2D3C PKHD1L1 CRIP2 SEMA3D CDH22 RAB11FIP5	4.86e-06	200	148	7	e65d4ae3d48f68c12edd5dc2c2f4e25e4acfadf1
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Lymphatic\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	FLT4 SH2D3C PKHD1L1 CRIP2 SEMA3D CDH22 RAB11FIP5	4.86e-06	200	148	7	4ec8e30dd241d83a1bba1c5967b6a4656afbfafd
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FLNC FLT4 SH2D3C PKHD1L1 BCL6B SEMA3D RAB11FIP5	4.86e-06	200	148	7	b515b2ab0c3f5928dd67f2f227fc932451c272bb
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SASH1 FREM1 TIAM1 SPHKAP NAV2 ASTN2 PRKG2	4.86e-06	200	148	7	a7022762c1d8aedb7b3e9605873b1e68b9907b35
ToppCell	Biopsy_Control_(H.)-Endothelial-Lymphatic_Endothelial_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	FLNC FLT4 PKHD1L1 CRIP2 BCL6B SEMA3D RAB11FIP5	4.86e-06	200	148	7	8cf218887ab030b7625610cb65b595170a17ebec
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FLNC FLT4 SH2D3C PKHD1L1 BCL6B SEMA3D RAB11FIP5	4.86e-06	200	148	7	35f6c7f2469d12748c27f2a5d4a161ef839b4a07
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-B3GAT2--L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SASH1 FREM1 TIAM1 SPHKAP NAV2 ASTN2 PRKG2	4.86e-06	200	148	7	2131c8e7fa054b79906eaf60536da892438b09cd
ToppCell	LPS-antiTNF-Unknown-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CIT NEK2 MLIP MKI67 POLQ WDR17	4.88e-06	130	148	6	615c233c7c2600c1c2bc5cf5b1c501fc474564ef
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLNC FLT4 SH2D3C PKHD1L1 BCL6B SEMA3D	1.72e-05	162	148	6	2ac02523348660e514d464f8f2434ee0c312d784
ToppCell	facs-Kidney-nan-3m-Lymphocytic-T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 IKZF1 NEK2 GZMH ADAMTS17 MTRR	1.78e-05	163	148	6	385b24e18df5ef92108483de312d6c85a1e6d145
ToppCell	facs-Kidney-nan-3m-Lymphocytic-T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 IKZF1 NEK2 GZMH ADAMTS17 MTRR	1.78e-05	163	148	6	8004cc0b3428be08b89957b563cd8799f822d931
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 SH2D3C PKHD1L1 BCL6B SEMA3D CDH22	1.84e-05	164	148	6	a784f47f67a5eda84d58ad7d9400e3978edbb487
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 SH2D3C PKHD1L1 BCL6B SEMA3D CDH22	1.84e-05	164	148	6	1a1795969673232191425dde84ab24ee6a98143f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 SH2D3C PKHD1L1 BCL6B SEMA3D CDH22	1.84e-05	164	148	6	8f074940afdbda88a4b697a7ddc687e09a4b818b
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT4 SASH1 SH2D3C PKHD1L1 SEMA3D CDH22	1.90e-05	165	148	6	50a8513d8d2630861499393a7f102b35366bad37
ToppCell	Endothelial-B-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	FLT4 ZNF208 PKHD1L1 CRIP2 SEMA3D CDH22	1.90e-05	165	148	6	b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCell	368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|368C / Donor, Lineage, Cell class and subclass (all cells)	JCAD FLT4 SASH1 SH2D3C BCL6B SP7	1.97e-05	166	148	6	30a991fc3275b571d53bd0976df4789e5d40b01d
ToppCell	COPD-Lymphoid-ILC_B\|Lymphoid / Disease state, Lineage and Cell class	HOXA3 WDR74 IFITM5 TIAM1 ARHGAP31 IL4I1	1.97e-05	166	148	6	e2cad1db536d5ad5a34c337c19b5e7d1a2851552
ToppCell	368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	JCAD FLT4 SASH1 SH2D3C BCL6B SP7	1.97e-05	166	148	6	76b4cd32698900797ec009f17e50ea7ae36b85f4
ToppCell	Endothelial-B-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	FLNC FLT4 ZNF831 PKHD1L1 BCL6B SEMA3D	1.97e-05	166	148	6	c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8\|TCGA-Thryoid / Sample_Type by Project: Shred V9	LCA5 IKZF2 PCDHGC5 PCDHGC4 NAV2 PDZRN4	2.11e-05	168	148	6	00646601548b0fee42ae16bfa5e93603bc7c5129
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TUT1 PKHD1L1 SEMA3D SPHKAP ADAMTS17 TRPM1	2.18e-05	169	148	6	0cece9b2bb1f58e465c20ec8735a4fc3c1021f03
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TUT1 PKHD1L1 SEMA3D SPHKAP ADAMTS17 TRPM1	2.18e-05	169	148	6	6937c46b119d4ce382fc8c2fa5925ede5ae89c81
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	CIT NEK2 GZMH MKI67 MAP3K9 POLQ	2.33e-05	171	148	6	4ede6e916e593f208f2f8ccf82ef2335e061fc86
ToppCell	Bronchial_Biopsy-Endothelial-Lymphatic\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	IL12RB1 FLNC FLT4 PKHD1L1 SEMA3D PCDHGA8	2.41e-05	172	148	6	c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JCAD GOLGA8S SH2D3C PKHD1L1 SEMA3D ARHGAP31	2.41e-05	172	148	6	c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCell	PND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IFT22 MGLL SEMA3D MAP3K10 RAB11FIP5 MMP12	2.49e-05	173	148	6	03b50b2376d353748a32bf14a9fc8341ea61dbca
ToppCell	PND28-Endothelial-Endothelial_lymphatic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IFT22 MGLL SEMA3D MAP3K10 RAB11FIP5 MMP12	2.49e-05	173	148	6	2978c744d3c8dcaa2b9bb225abf846f82e8f9176
ToppCell	PND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IFT22 MGLL SEMA3D MAP3K10 RAB11FIP5 MMP12	2.49e-05	173	148	6	12da47b90aecedaa31764ff7ddb853ee39123e9d
Drug	Gemfibrozil [25812-30-0]; Up 200; 16uM; PC3; HT_HG-U133A	TRIM25 WAS ANK3 CYP27B1 TUT1 SYDE1 ZNF10 MCM9 ARNT2	5.42e-06	195	148	9	2113_UP
Drug	Trapidil [15421-84-8]; Up 200; 19.4uM; MCF7; HT_HG-U133A	TRIM25 WAS IKZF1 TUT1 SYDE1 COBL ASTN2 PRKG2 HCFC1	6.14e-06	198	148	9	7475_UP
Drug	Loperamide hydrochloride [34552-83-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A	DNAJB12 IL12RB1 FLT4 WDR33 IKZF1 KIDINS220 MAP3K9 GMPR HCFC1	6.66e-06	200	148	9	5632_DN
Disease	childhood trauma measurement, alcohol consumption measurement	DNAJB12 PCDHGC5 PCDHGC4 PCDHGA9 PCDHGA8	2.51e-05	71	143	5	EFO_0007878, EFO_0007979
Disease	gastrointestinal system disease (is_implicated_in)	TF MECP2	6.97e-05	3	143	2	DOID:77 (is_implicated_in)
Disease	Partial Fetal Alcohol Syndrome	ANK3 RPS6KA1	2.31e-04	5	143	2	C3661483
Disease	Alcohol Related Neurodevelopmental Disorder	ANK3 RPS6KA1	2.31e-04	5	143	2	C0814154
Disease	axial length measurement, refractive error	GBE1 ASTN2	3.45e-04	6	143	2	EFO_0005318, MONDO_0004892
Disease	Alcohol Related Birth Defect	ANK3 RPS6KA1	3.45e-04	6	143	2	C3146244
Disease	Congenital ocular coloboma (disorder)	WDR37 ALDH7A1	8.21e-04	9	143	2	C0009363
Disease	unipolar depression, bipolar disorder	ANK3 PCLO TUBGCP6 ASTN2 RPRD2	1.00e-03	156	143	5	EFO_0003761, MONDO_0004985
Disease	Disorders of Intracellular Cobalamin Metabolism	MTRR HCFC1	1.02e-03	10	143	2	cv:CN043592
Disease	forced expiratory volume, response to bronchodilator	MGLL TUT1 UROC1 RUVBL1 ARNT2 COBL SPAG17 MMP12	1.52e-03	445	143	8	EFO_0004314, GO_0097366
Disease	Fetal Alcohol Spectrum Disorders	ANK3 RPS6KA1	1.76e-03	13	143	2	C2985290
Disease	Autistic Disorder	TF MECP2 PIK3CG RAB11FIP5 ASTN2 STK39	1.76e-03	261	143	6	C0004352
Disease	L2 Acute Lymphoblastic Leukemia	IKZF2 IKZF1 MTRR	1.85e-03	50	143	3	C0023453
Disease	lymphocyte count	JCAD PCDHGC5 PCDHGC4 PCDHGA9 RPS6KA1 SANBR IKZF1 UROC1 ZNF831 SLC4A1 HOXA3 DIP2A SEMA3D ARHGAP31 HNRNPLL PCDHGA8	2.01e-03	1464	143	16	EFO_0004587
Disease	Childhood Acute Lymphoblastic Leukemia	IKZF2 IKZF1 MTRR	2.07e-03	52	143	3	C0023452
Disease	Metastatic melanoma	FLT4 MAP3K9 MAP3K10	2.31e-03	54	143	3	C0278883
Disease	Hepatitis	TF PARP1	2.35e-03	15	143	2	C0019158
Disease	esophageal carcinoma, gastric carcinoma	SASH1 TRPM1	3.02e-03	17	143	2	EFO_0000178, EFO_0002916
Disease	Fetal Alcohol Syndrome	ANK3 RPS6KA1	3.02e-03	17	143	2	C0015923
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	IKZF2 IKZF1 MTRR	3.27e-03	61	143	3	C1961102
Disease	glucose homeostasis measurement, acute insulin response measurement	IKZF1 ASTN2	3.39e-03	18	143	2	EFO_0006831, EFO_0006896
Disease	emphysema pattern measurement	JCAD MMP12	3.78e-03	19	143	2	EFO_0005850
Disease	Disorder of eye	LCA5 OPA1 FREM1 TRPM1 CNGB1	3.81e-03	212	143	5	C0015397
Disease	hearing loss	ARHGEF28 CRIP3 IL4I1	4.26e-03	67	143	3	EFO_0004238
Disease	Osteogenesis imperfecta	IFITM5 SP7	4.61e-03	21	143	2	cv:C0029434
Disease	HIV-1 infection, Susceptibility to viral and mycobacterial infections	NAV2 PRKG2	4.61e-03	21	143	2	EFO_0000180, Orphanet_391311
Disease	Profound Mental Retardation	KDM5A UROC1 MECP2 PARP1	4.75e-03	139	143	4	C0020796
Disease	Mental Retardation, Psychosocial	KDM5A UROC1 MECP2 PARP1	4.75e-03	139	143	4	C0025363
Disease	Mental deficiency	KDM5A UROC1 MECP2 PARP1	4.75e-03	139	143	4	C0917816
Disease	DNA methylation	JCAD IKZF2 SASH1 FREM1 MDN1 TIAM1 PIK3CG MMP12 NOS1AP	4.81e-03	656	143	9	GO_0006306

Protein segments in the cluster

Peptide	Gene	Start	Entry
VTAPPAAHAKHGSRD	AMOTL2	711	Q9Y2J4
KPLTTSGFHHSEEGT	CEP170	561	Q5SW79
PLTSADEHVHSKLEG	CEP170	1056	Q5SW79
GVKDRDEGLGPHHSS	CCDC17	601	Q96LX7
KTSGLVVESGHGVSH	ACTL7B	191	Q9Y614
KHLPIHHGSTDAGDS	AP2B1	591	P63010
HSHAGELEALGGVKP	SLC4A1	161	P02730
PTIVTGLGHDASIAH	ALDH7A1	411	P49419
AGTEEIIGGHEAKPH	GZMH	16	P20718
DSGATHTTAIPVHDG	ACTL6A	171	O96019
HLLSIVKATGHSGDP	CFAP46	766	Q8IYW2
HLHSGASGPKAEALL	CHRNA2	441	Q15822
PSGHKHLTVEELFGT	DCP1A	211	Q9NPI6
KTLTSGGHAEHEGKP	CRIP1	36	P50238
PSVGDVFHGISKEDH	FAM193A	641	P78312
NLVKESGTEHHRGPS	CIT	1901	O14578
SQVTHTLDSLGHPGE	ASTN2	316	O75129
KATGHSPLELVGHLE	ASXL1	1386	Q8IXJ9
PAKLSIGHHGERSLE	ADAMTS17	291	Q8TE56
HKVTGRHGSECPALS	ADAMTS17	1001	Q8TE56
GHSGKAFSSSVVHVP	ARNT2	531	Q9HBZ2
GTDLKTSSHPEMLHG	MLIP	181	Q5VWP3
HGAKSPDGTRVHNAF	PDZRN4	1016	Q6ZMN7
LGASPHHSSSGEEKA	RAB11FIP5	491	Q9BXF6
REDGLPKGHHVTDSE	IWS1	56	Q96ST2
SQPEAGGSHHKVSVS	HNRNPLL	61	Q8WVV9
GHSLGLGHSSDPKAV	MMP12	221	P39900
AAHHLVLTASDGGKP	PCDHGA8	206	Q9Y5G5
DSGLEHSAHVLEKGG	PARP1	536	P09874
HHLLSEPGGRAKDAA	GOLGA8S	486	H3BPF8
RTVIADGSLSHPKEH	PALM2	221	Q8IXS6
GSGHQILPFHESSKD	ARHGEF28	1631	Q8N1W1
GQPEKDLESGAHLTH	CYP27B1	281	O15528
KDLPAGRHSHAVSTA	HCFC1	1226	P51610
GVQGKEHSAHLDPSA	POC5	391	Q8NA72
ELEDDSHSGKRGIPH	KIDINS220	1616	Q9ULH0
GSHISLPSGFEHKIT	MAP3K10	471	Q02779
LHHFVGEGESKRSLP	MDN1	3201	Q9NU22
SDGGHTVLHRDLKPA	NEK2	131	P51955
SSAGGHPKAHELSEA	HOXA3	56	O43365
PKALIFVSHGAGEHS	MGLL	41	Q99685
ESTGRGKPHFTLEGH	GLB1L3	71	Q8NCI6
SITNDKGHDGHRTPT	ERVMER34-1	266	Q9H9K5
GHEDGPAALAHRKTS	JCAD	46	Q9P266
HASHEDSGKALAPKI	MTRR	506	Q9UBK8
AAVGPQKATGHADEH	EZHIP	121	Q86X51
SSVVEKGSHVHSGPT	PCLO	4641	Q9Y6V0
TAHHLVLTASDGGEP	PCDHGA9	206	Q9Y5G4
ASDAGSPSLHKHLTI	PCDHGC5	426	Q9Y5F6
KIEPHHTAVLGEGDS	PIR	211	O00625
HSIDVKFNGAHIPGS	FLNC	2476	Q14315
PKHGHLENTTTGEFI	FREM1	1676	Q5H8C1
GHHLQDISFSTPKGE	LCA5	521	Q86VQ0
THGHVSDASISLGEP	TUBGCP6	1241	Q96RT7
GTIGHVDHGKTTLTA	TUFM	61	P49411
TTHTHREPAGDGKSI	MKI67	1051	P46013
HTHKEPASGDEGIKV	MKI67	2631	P46013
DALTGHLRTHSVGKP	IKZF1	186	Q13422
SDDPIKFVDVGGHSH	PCDHGC4	756	Q9Y5F7
DALTGHLRTHSVGKP	IKZF2	181	Q9UKS7
ALVHDGDTVSVHRPG	PIP5K1A	421	Q99755
IDSGVGLAPHHAVEK	KDM5A	926	P29375
TPAKVLDASGHHETL	ITFG2	96	Q969R8
SKHPDGHSGNLTTDA	PRKG2	11	Q13237
LSEGPHHVALFKDSS	OPA1	331	O60313
AVSTEEGHNGPSVHK	BOD1L1	2401	Q8NFC6
ESHVGISSHEGKVAS	GBE1	201	Q04446
AHHKPGSGDDKGSLS	IFT22	121	Q9H7X7
GNLASHRTVHTGEKP	BCL6B	341	Q8N143
GPHVSAAAKDSVEGI	PCIF1	346	Q9H4Z3
IAGIPKLEHGDSHQT	LINC01599	196	Q8WXQ3
DSHPKLSSGIHGDEE	FNDC1	866	Q4ZHG4
EGHSPKAQPGSTDRH	FNDC1	961	Q4ZHG4
SDGTEGKVYHPTHLG	POLQ	601	O75417
TTHATHRKAGGTDAP	DNAJB12	66	Q9NXW2
HPASHDVGKGIRVAL	COBL	601	O75128
GPGETDESHKESSQH	HAS2	156	Q92819
AGLFEHKSAVSPDVH	ANK3	2291	Q12955
KTLTAGSHAEHDGVP	CRIP3	156	Q6Q6R5
GNASAAGTPHHVSVK	IL12RB1	441	P42701
SKAGAHTALTLGAPH	IFITM5	16	A6NNB3
LDGEHHFTVDPKTGV	CDH22	211	Q9UJ99
ISHASDLVGGGHIKE	E4F1	131	Q66K89
TAATLEAHKRGHTGP	E4F1	446	Q66K89
SKTLTPGGHAEHDGK	CRIP2	36	P52943
IIAHTETKGPLGDSH	DIP2A	1371	Q14689
ADSAHGLKGHIISDG	GMPR	206	P36959
EGGSHTGSKVSHPQE	NOS1AP	246	O75052
KDHGGIFSRDAPTHL	RPRD2	1221	Q5VT52
HERTHTGEKPFGCTI	SALL3	1131	Q9BXA9
ESPHFHLGLKSLVDG	MAP3K9	631	P80192
AEGLSHTPTVKHLEA	PELI1	256	Q96FA3
TVKHGAGAEISTVHP	PIP4K2C	391	Q8TBX8
HGVASSPSHDLAKEE	IL4I1	531	Q96RQ9
HHSAEPAEAGKAETS	MECP2	51	P51608
EDHSHVSPGATKIAV	MCM9	936	Q9NXL9
SGPGLASAVDFKHHI	SYDE1	576	Q6ZW31
KGIAGEDTKSPHHSE	SPHKAP	836	Q2M3C7
GAARESTHHKEKVGP	TRIM41	501	Q8WV44
SSSDGHIDPQHAAGK	TAB3	101	Q8N5C8
DGGAKAAPSHHKISF	NKX1-2	6	Q9UD57
GAGKPSVHSQVAELH	ODAD3	61	A5D8V7
THDLVGPELTSGHNT	NBEAL2	916	Q6ZNJ1
HGVSHKVDDSSGSIG	GARS1	641	P41250
HEKEPLASSASSHPG	NAV2	331	Q8IVL1
ISGPDSGVIVHKDAH	WDR17	156	Q8IZU2
ETPVGHDAVSKTGRH	SANBR	101	Q6NSI8
AVGEDGAKGSAHISH	SPAG17	2146	Q6Q759
KDTAFTRSLGPTHDH	SEMA3D	211	O95025
AHGADPTHRLKDGST	ANKHD1	656	Q8IWZ3
VKGEEGSAAPDQHTH	CNGB1	1161	Q14028
CKSPETALLHVAGHG	PIK3CG	51	P48736
TETLVTHGKGGPAHS	RHBDD3	366	Q9Y3P4
SDAVLHHEDLIGKPG	TPST2	261	O60704
HHEDLIGKPGGVSLS	TPST2	266	O60704
ADGTHKSGESPTHFK	TDP1	306	Q9NUW8
AHPHVVATGGKENAL	WDR74	141	Q6RFH5
RSHDVKNGGELTHPT	USP42	411	Q9H9J4
HPHAHAASEVLEKSG	USPL1	841	Q5W0Q7
SPHGKDLLFKDSAHG	TF	306	P02787
GRSGIDHNSIPKHAV	TIAM1	481	Q13009
KGSSLSAHGPEAHAT	SLC16A4	211	O15374
HGAHIGKPISSSASV	SMC1B	66	Q8NDV3
SDHLSKHQRTHGEPG	SP7	366	Q8TDD2
KAPVVLSRDHHDVSG	UROC1	536	Q96N76
SHAALAERGPKGHEA	TUT1	731	Q9H6E5
PTIKGIDHSHLASSE	SPATA31D1	341	Q6ZQQ2
SSGDPGEHDPASTHK	TRIM25	361	Q14258
DGKALSGRHSPHALV	FLT4	371	P35916
ADIGAPSGFKHVSHV	WAS	236	P42768
EFEGTHHPLGTKEGV	SASH1	956	O94885
AEGKELGTHLGHSSP	ARHGAP31	1041	Q2M1Z3
GSLTGHKGHTVIPHS	PKHD1L1	2801	Q86WI1
ASHSHVKGLGLDESG	RUVBL1	16	Q9Y265
LAKLHGASAGAPHSA	SKOR2	636	Q2VWA4
TSHPSHKEVVDGSPA	VILL	711	O15195
STGVISHVGDALKDH	TRPM1	141	Q7Z4N2
SHLIGHQKTHTGEEP	ZNF10	306	P21506
AGHVGSVNSIKFHPS	WDR37	196	Q9Y2I8
HIVDFHKSTGPLGTH	ZUP1	441	Q96AP4
PSSLTEHKATHAGEK	ZNF208	1041	O43345
PVSHGAHFSGDVSKA	XPOT	461	O43592
QHSVDLTGHEGVPTA	ZNF16	191	P17020
APKTHGESDKGPHTS	SH2D3C	456	Q8N5H7
PDKSHFGLIVGDSQH	ZNF148	671	Q9UQR1
VPKSGRSSSLDGEHH	WDR33	1271	Q9C0J8
DQKSVHGTFSPDHGT	TEX15	2461	Q9BXT5
GSKGTFPHHDIATSV	ZNF831	1476	Q5JPB2
RVPGSSGHLHKTEDG	STK39	366	Q9UEW8
SGHYIAHVKDPQSGE	USP48	351	Q86UV5
GTHLEKALHRAPTSE	TTC34	326	A8MYJ7
GSCLIHERTHTGEKP	ZNF669	291	Q96BR6
HSAHDPGLSKTSTAE	USP54	1361	Q70EL1
TDASAGPAIKLHHVT	ELFN2	291	Q5R3F8
ITHHVKAGSEKADPS	RPS6KA1	46	Q15418