Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	carbonate dehydratase activity	CA13 CA1 CA2 CA3 CA5A CA6	9.80e-11	16	99	6	GO:0004089
GeneOntologyMolecularFunction	carbon-oxygen lyase activity	CA13 POLQ CA1 CA2 CA3 CA5A CA6	1.67e-07	82	99	7	GO:0016835
GeneOntologyMolecularFunction	transition metal ion binding	FLG AOC1 HDAC6 CYP4B1 CYP17A1 CA13 MMP21 NR6A1 SHANK3 MMP25 DHH RPTN CPXM1 PAM MMP12 USP3 CA1 CA2 CA3 CA5A CA6	2.92e-07	1189	99	21	GO:0046914
GeneOntologyMolecularFunction	hydro-lyase activity	CA13 CA1 CA2 CA3 CA5A CA6	6.89e-07	63	99	6	GO:0016836
GeneOntologyMolecularFunction	lyase activity	CYP17A1 CA13 PAM POLQ CA1 CA2 CA3 CA5A CA6	1.10e-06	212	99	9	GO:0016829
GeneOntologyMolecularFunction	zinc ion binding	HDAC6 CA13 MMP21 NR6A1 SHANK3 MMP25 DHH CPXM1 PAM MMP12 USP3 CA1 CA2 CA3 CA5A CA6	7.55e-06	891	99	16	GO:0008270
GeneOntologyMolecularFunction	cyanamide hydratase activity	CA1 CA2	2.43e-05	2	99	2	GO:0018820
GeneOntologyMolecularFunction	metalloendopeptidase activity	YBEY MMP21 MMP25 THOP1 MMP12	3.29e-04	120	99	5	GO:0004222
GeneOntologyMolecularFunction	calcium ion binding	FLG HSPG2 AOC1 SWAP70 MAN1C1 CRB1 DHH CELSR2 SPOCK3 RPTN PAM MMP12	3.31e-04	749	99	12	GO:0005509
GeneOntologyMolecularFunction	arylesterase activity	CA1 CA2	3.60e-04	6	99	2	GO:0004064
GeneOntologyMolecularFunction	metallopeptidase activity	YBEY MMP21 MMP25 THOP1 CPXM1 MMP12	4.85e-04	200	99	6	GO:0008237
GeneOntologyMolecularFunction	carboxylic ester hydrolase activity	CES1 LYPLA2 TARS2 CA1 CA2	1.11e-03	157	99	5	GO:0052689
GeneOntologyMolecularFunction	peptidase activity	YBEY MMP21 PSMB11 MMP25 THOP1 DHH PCSK7 CPXM1 MMP12 USP3	1.51e-03	654	99	10	GO:0008233
GeneOntologyBiologicalProcess	one-carbon metabolic process	CA13 CA1 CA2 CA3 CA5A CA6	6.01e-08	44	98	6	GO:0006730
Domain	Carb_anhydrase	CA13 PTPRG CA1 CA2 CA3 CA5A CA6	1.76e-12	17	99	7	PF00194
Domain	Carb_anhydrase	CA13 PTPRG CA1 CA2 CA3 CA5A CA6	1.76e-12	17	99	7	SM01057
Domain	-	CA13 PTPRG CA1 CA2 CA3 CA5A CA6	1.76e-12	17	99	7	3.10.200.10
Domain	ALPHA_CA_2	CA13 PTPRG CA1 CA2 CA3 CA5A CA6	1.76e-12	17	99	7	PS51144
Domain	Carbonic_anhydrase_a	CA13 PTPRG CA1 CA2 CA3 CA5A CA6	1.76e-12	17	99	7	IPR001148
Domain	Carbonic_anhydrase_a-class_CS	CA13 CA1 CA2 CA3 CA5A CA6	1.71e-11	12	99	6	IPR018338
Domain	Carbonic_anhydrase_a-class	CA13 CA1 CA2 CA3 CA5A CA6	9.16e-11	15	99	6	IPR023561
Domain	ALPHA_CA_1	CA13 CA1 CA2 CA3 CA5A CA6	9.16e-11	15	99	6	PS00162
Domain	CA2	CA13 CA2	2.78e-05	2	99	2	IPR018443
Domain	Pept_M10A_stromelysin-type	MMP21 MMP25 MMP12	1.11e-04	18	99	3	IPR016293
Domain	PG_binding_1	MMP21 MMP25 MMP12	1.54e-04	20	99	3	PF01471
Domain	Peptidoglycan-bd-like	MMP21 MMP25 MMP12	1.54e-04	20	99	3	IPR002477
Domain	CRAL_TRIO	PRUNE2 TRIO KALRN	1.79e-04	21	99	3	PF00650
Domain	Hemopexin-like_dom	MMP21 MMP25 MMP12	2.37e-04	23	99	3	IPR000585
Domain	-	PRUNE2 TRIO KALRN	2.37e-04	23	99	3	3.40.525.10
Domain	Hemopexin-like_repeat	MMP21 MMP25 MMP12	2.37e-04	23	99	3	IPR018487
Domain	HEMOPEXIN	MMP21 MMP25 MMP12	2.37e-04	23	99	3	PS00024
Domain	-	MMP21 MMP25 MMP12	2.37e-04	23	99	3	2.110.10.10
Domain	HEMOPEXIN_2	MMP21 MMP25 MMP12	2.37e-04	23	99	3	PS51642
Domain	HX	MMP21 MMP25 MMP12	2.37e-04	23	99	3	SM00120
Domain	M10A_MMP	MMP21 MMP25 MMP12	2.37e-04	23	99	3	IPR033739
Domain	Hemopexin	MMP21 MMP25 MMP12	2.37e-04	23	99	3	PF00045
Domain	Pept_M10A	MMP21 MMP25 MMP12	2.37e-04	23	99	3	IPR021190
Domain	Peptidase_M10	MMP21 MMP25 MMP12	2.70e-04	24	99	3	PF00413
Domain	SEC14	PRUNE2 TRIO KALRN	3.05e-04	25	99	3	SM00516
Domain	CRAL_TRIO	PRUNE2 TRIO KALRN	3.85e-04	27	99	3	PS50191
Domain	CRAL-TRIO_dom	PRUNE2 TRIO KALRN	4.30e-04	28	99	3	IPR001251
Domain	Peptidase_Metallo	MMP21 MMP25 MMP12	4.78e-04	29	99	3	IPR006026
Domain	ZnMc	MMP21 MMP25 MMP12	4.78e-04	29	99	3	SM00235
Domain	-	MMP21 MMP25 THOP1 MMP12	9.04e-04	81	99	4	3.40.390.10
Domain	MetalloPept_cat_dom	MMP21 MMP25 THOP1 MMP12	9.04e-04	81	99	4	IPR024079
Domain	LAM_G_DOMAIN	HSPG2 CRB1 CELSR2	1.07e-03	38	99	3	PS50025
Domain	Laminin_G_2	HSPG2 CRB1 CELSR2	1.24e-03	40	99	3	PF02210
Domain	CYSTEINE_SWITCH	MMP21 MMP25 MMP12	1.33e-03	41	99	3	PS00546
Domain	ZnF_UBP	HDAC6 USP3	1.48e-03	11	99	2	SM00290
Domain	Pept_M10_metallopeptidase	MMP21 MMP25 MMP12	1.53e-03	43	99	3	IPR001818
Domain	LamG	HSPG2 CRB1 CELSR2	1.63e-03	44	99	3	SM00282
Domain	ZINC_PROTEASE	MMP21 MMP25 THOP1 MMP12	1.83e-03	98	99	4	PS00142
Pathway	REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE	CA13 CA1 CA2 CA3 CA5A CA6	1.67e-11	12	75	6	M671
Pathway	REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE	CA13 CA1 CA2 CA3 CA5A CA6	1.67e-11	12	75	6	MM14574
Pathway	KEGG_NITROGEN_METABOLISM	CA13 CA1 CA2 CA3 CA5A CA6	1.74e-09	23	75	6	M4629
Pubmed	A systematic quantification of carbonic anhydrase transcripts in the mouse digestive system.	CA13 CA1 CA2 CA3 CA5A CA6	4.70e-13	12	101	6	17362527
Pubmed	A systematic survey of carbonic anhydrase mRNA expression during mammalian inner ear development.	CA13 CA1 CA2 CA3 CA5A CA6	3.71e-11	22	101	6	23233153
Pubmed	Carbonic anhydrases in the mouse harderian gland.	CA13 CA2 CA3 CA6	4.65e-09	8	101	4	20820888
Pubmed	Expression patterns and subcellular localization of carbonic anhydrases are developmentally regulated during tooth formation.	CA13 CA2 CA3 CA6	2.18e-08	11	101	4	24789143
Pubmed	Using evolutionary rates to investigate protein functional divergence and conservation. A case study of the carbonic anhydrases.	CA1 CA2 CA3	2.38e-08	3	101	3	12930737
Pubmed	Mapping of mouse carbonic anhydrase-3, Car-3: another locus in the homologous region of mouse chromosome 3 and human chromosome 8.	CA1 CA2 CA3	2.38e-08	3	101	3	2111277
Pubmed	Characterization of CA XIII, a novel member of the carbonic anhydrase isozyme family.	CA13 CA2 CA5A	2.38e-08	3	101	3	14600151
Pubmed	Expression of a novel carbonic anhydrase, CA XIII, in normal and neoplastic colorectal mucosa.	CA13 CA1 CA2	2.38e-08	3	101	3	15836783
Pubmed	Physical mapping of the human carbonic anhydrase gene cluster on chromosome 8.	CA1 CA2 CA3	2.38e-08	3	101	3	1916821
Pubmed	An analysis of expression patterns of genes encoding proteins with catalytic activities.	CA13 CA1 CA2 CA3 CA5A CA6	4.46e-08	67	101	6	17626619
Pubmed	Human carbonic anhydrases and carbonic anhydrase deficiencies.	CA1 CA2 CA3	2.37e-07	5	101	3	7574487
Pubmed	Sjögren's syndrome-like disease of C57BL/6.NOD-Aec1 Aec2 mice: gender differences in keratoconjunctivitis sicca defined by a cross-over in the chromosome 3 Aec1 locus.	CA1 CA2 CA3	8.25e-07	7	101	3	16918699
Pubmed	Structural insight into the inhibition of carbonic anhydrase by the COX-2-selective inhibitor polmacoxib (CG100649).	CA1 CA2	8.35e-06	2	101	2	27475498
Pubmed	Carbonic anhydrase activators. Activation of isoforms I, II, IV, VA, VII, and XIV with L- and D-phenylalanine and crystallographic analysis of their adducts with isozyme II: stereospecific recognition within the active site of an enzyme and its consequences for the drug design.	CA1 CA2	8.35e-06	2	101	2	16686544
Pubmed	Inhibition properties of some flavonoids on carbonic anhydrase I and II isoenzymes purified from human erythrocytes.	CA1 CA2	8.35e-06	2	101	2	28445001
Pubmed	Human carbonic anhydrases. XII. The complete primary structure of the C isozyme.	CA1 CA2	8.35e-06	2	101	2	4207120
Pubmed	The Effect of Nanoparticles on the Structure and Enzymatic Activity of Human Carbonic Anhydrase I and II.	CA1 CA2	8.35e-06	2	101	2	32992797
Pubmed	Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca2+ in knock-out mouse models of polycystic kidney disease.	HDAC6 PKD1	8.35e-06	2	101	2	28887310
Pubmed	Carbonic anhydrase activators: L-Adrenaline plugs the active site entrance of isozyme II, activating better isoforms I, IV, VA, VII, and XIV.	CA1 CA2	8.35e-06	2	101	2	17127057
Pubmed	Carbonic anhydrase enzymes regulate mast cell-mediated inflammation.	CA1 CA2	8.35e-06	2	101	2	27526715
Pubmed	Synthesis and in vitro inhibition effect of new pyrido[2,3-d]pyrimidine derivatives on erythrocyte carbonic anhydrase I and II.	CA1 CA2	8.35e-06	2	101	2	25165709
Pubmed	Expression of carbonic anhydrases I/II and the correlation to clinical aspects of oral squamous cell carcinoma analyzed using tissue microarray.	CA1 CA2	8.35e-06	2	101	2	22416960
Pubmed	Erythrocyte zinc and carbonic anhydrase levels in nondialyzed chronic kidney disease patients.	CA1 CA2	8.35e-06	2	101	2	14675565
Pubmed	Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase.	CA2 CA3	8.35e-06	2	101	2	12171926
Pubmed	Catalytic and inhibitor-binding properties of some active-site mutants of human carbonic anhydrase I.	CA1 CA2	8.35e-06	2	101	2	7758465
Pubmed	Carbonic anhydrase 2 and 3 as risk biomarkers for dilated cardiomyopathy associated heart failure.	CA2 CA3	8.35e-06	2	101	2	35016406
Pubmed	Carbonic anhydrase activation is associated with worsened pathological remodeling in human ischemic diabetic cardiomyopathy.	CA1 CA2	8.35e-06	2	101	2	24670789
Pubmed	Autoantibodies Against Carbonic Anhydrase I and II in Patients with Acute Myeloid Leukemia.	CA1 CA2	8.35e-06	2	101	2	28270370
Pubmed	Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP.	TRIO KALRN	8.35e-06	2	101	2	26858404
Pubmed	Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII, and XIV with l- and d-histidine and crystallographic analysis of their adducts with isoform II: engineering proton-transfer processes within the active site of an enzyme.	CA1 CA2	8.35e-06	2	101	2	16807956
Pubmed	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	CA13 CA1 CA2 CA3	1.28e-05	49	101	4	23720494
Pubmed	Expression and functional analysis of genes deregulated in mouse placental overgrowth models: Car2 and Ncam1.	CA1 CA2 CA3	1.88e-05	18	101	3	16247769
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	BRPF3 DCAF6 HDAC6 YBEY PKP4 MMP21 RNF213 RSBN1 LARP4B ZNF469 PLD1 KDM1A PRRC2B	2.13e-05	1116	101	13	31753913
Pubmed	Evolution of mammalian carbonic anhydrase loci by tanden duplication: close linkage of Car-1 and Car-2 to the centromere region of chromosome 3 of the mouse.	CA1 CA2	2.50e-05	3	101	2	825106
Pubmed	Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action.	TRIO KALRN	2.50e-05	3	101	2	31801062
Pubmed	Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors.	CA1 CA2	2.50e-05	3	101	2	19206230
Pubmed	Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating thioureido-sulfanilyl scaffolds.	CA1 CA2	2.50e-05	3	101	2	15837325
Pubmed	Kalirin, a cytosolic protein with spectrin-like and GDP/GTP exchange factor-like domains that interacts with peptidylglycine alpha-amidating monooxygenase, an integral membrane peptide-processing enzyme.	KALRN PAM	2.50e-05	3	101	2	9139723
Pubmed	Genes on chromosome 3 of the mouse.	CA1 CA2	2.50e-05	3	101	2	820740
Pubmed	Evaluation of acetylcholinesterase and carbonic anhydrase inhibition profiles of 1,2,3,4,6-pentasubstituted-4-hydroxy-cyclohexanes.	CA1 CA2	2.50e-05	3	101	2	28613396
Pubmed	HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells.	HDAC6 PKD1	2.50e-05	3	101	2	23152903
Pubmed	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	CELSR2 PCSK7 WDR1	3.04e-05	21	101	3	21943158
Pubmed	Functional interactions between matrix metalloproteinases and glycosaminoglycans.	MMP21 MMP25 MMP12	3.52e-05	22	101	3	23421805
Pubmed	Discovery of potent carbonic anhydrase, acetylcholinesterase, and butyrylcholinesterase enzymes inhibitors: The new amides and thiazolidine-4-ones synthesized on an acetophenone base.	CA1 CA2	4.99e-05	4	101	2	28544359
Pubmed	Carbonic anhydrase inhibitors: Synthesis, molecular docking, cytotoxic and inhibition of the human carbonic anhydrase isoforms I, II, IX, XII with novel benzenesulfonamides incorporating pyrrole, pyrrolopyrimidine and fused pyrrolopyrimidine moieties.	CA1 CA2	4.99e-05	4	101	2	24878360
Pubmed	In Vitro Identification of Histatin 5 Salivary Complexes.	FLG DMBT1 CA6	6.61e-05	27	101	3	26544073
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	AOC1 HDAC6 CYP17A1 HSPH1 UNC13D PATL1 CPT2 ANKRD6 LARP4B THOP1 PLD1 USP3	7.37e-05	1084	101	12	11544199
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	GPRASP1 ILK HDAC6 PKP4 TARS2 RSBN1 PKD1 DMBT1 WDR1 NME4 MYB	7.99e-05	925	101	11	28986522
Pubmed	Assembly of high order G alpha q-effector complexes with RGS proteins.	TRIO KALRN	8.30e-05	5	101	2	18936096
Pubmed	Proprotein convertase expression and localization in epidermis: evidence for multiple roles and substrates.	FLG PCSK7	8.30e-05	5	101	2	11380615
Pubmed	Inhibition of Platelet GPVI Protects Against Myocardial Ischemia-Reperfusion Injury.	UNC13D PLD1	1.24e-04	6	101	2	26916731
Pubmed	Receptor protein tyrosine phosphatases are novel components of a polycystin complex.	PTPRG PKD1	1.24e-04	6	101	2	21126580
Pubmed	The AXB and BXA set of recombinant inbred mouse strains.	CES1 CA2	1.24e-04	6	101	2	1477475
Pubmed	Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin.	HSPH1 WDR1 CA1 CA2	1.41e-04	90	101	4	1602151
Pubmed	Nuclear receptors Sf1 and Dax1 function cooperatively to mediate somatic cell differentiation during testis development.	CYP17A1 DHH	1.74e-04	7	101	2	15829514
Pubmed	Genes for the neuronal immunoglobulin domain cell adhesion molecules neurofascin and Nr-CAM map to mouse chromosomes 1 and 12 and homologous human chromosomes.	LCT PAM	1.74e-04	7	101	2	8672144
Pubmed	DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity.	DCAF6 HDAC6 WDR1 KDM1A	2.04e-04	99	101	4	34161765
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	HSPG2 HDAC6 RNF213 TARS2 CPT2 RSBN1 NEU2 THOP1 LMF2 CELSR2 MRC2 PAM NME4	2.96e-04	1451	101	13	30550785
Pubmed	Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.	CELSR2 WDR1	2.97e-04	9	101	2	18179892
Pubmed	Female development in mammals is regulated by Wnt-4 signalling.	CYP17A1 DHH	3.70e-04	10	101	2	9989404
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	PKP4 PATL1 LARP4B ELP2 PLD1 KDM1A PRRC2B	4.10e-04	462	101	7	31138677
Pubmed	Basement membrane remodelling regulates mouse embryogenesis.	HSPG2 MMP25	4.51e-04	11	101	2	32523119
Pubmed	Genotyping new BXD recombinant inbred mouse strains and comparison of BXD and consensus maps.	CES1 CA2	4.51e-04	11	101	2	10087289
Pubmed	P62/SQSTM1 is a novel leucine-rich repeat kinase 2 (LRRK2) substrate that enhances neuronal toxicity.	HDAC6 HSPH1	5.41e-04	12	101	2	29519959
Pubmed	Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation.	PKP4 SHANK3 PAM	5.59e-04	55	101	3	24200680
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PRUNE2 SWAP70 HSPH1 RNF213 ANKRD6 SHANK3 LARP4B	6.02e-04	493	101	7	15368895
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	HDAC6 TRIO LARP4B CELSR2 PLD1 KDM1A	6.36e-04	358	101	6	32460013
Pubmed	R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling.	CYP17A1 DHH	7.43e-04	14	101	2	18250097
Pubmed	Metalloproteinases promote plaque rupture and myocardial infarction: A persuasive concept waiting for clinical translation.	MMP25 MMP12	7.43e-04	14	101	2	25636537
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	FLG MAN1C1 LYPLA2 TARS2 CPT2 CRB1 CD1C SCNN1D KDM1A CA6	8.44e-04	1031	101	10	16710414
Pubmed	Functional Analysis of Mmd2 and Related PAQR Genes During Sex Determination in Mice.	DHH CELSR2	8.55e-04	15	101	2	35306493
Pubmed	Lineage specification of ovarian theca cells requires multicellular interactions via oocyte and granulosa cells.	CYP17A1 DHH	8.55e-04	15	101	2	25917826
Pubmed	Mapping lineage progression of somatic progenitor cells in the mouse fetal testis.	CYP17A1 DHH	8.55e-04	15	101	2	27621062
Pubmed	Gonadal differentiation, sex determination and normal Sry expression in mice require direct interaction between transcription partners GATA4 and FOG2.	CYP17A1 DHH	8.55e-04	15	101	2	12223418
Pubmed	Infectivities of human and other primate lentiviruses are activated by desialylation of the virion surface.	MAN1C1 NEU2	8.55e-04	15	101	2	8892864
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	FLG NCAPD3 ILK HDAC6 TRIO SHANK3 NME4 PRRC2B	9.15e-04	689	101	8	36543142
Pubmed	Paleocortex is specified in mice in which dorsal telencephalic patterning is severely disrupted.	WNT2B NEU2	9.76e-04	16	101	2	14566948
Pubmed	Molecular genetic studies of Wnt signaling in the mouse.	WNT2B ANKRD6	9.76e-04	16	101	2	10585256
Pubmed	A mouse linkage testing stock possessing multiple copies of the endogenous ecotropic murine leukemia virus genome.	CES1 MYB	9.76e-04	16	101	2	2571572
Pubmed	c-Met and NF-κB-dependent overexpression of Wnt7a and -7b and Pax2 promotes cystogenesis in polycystic kidney disease.	WNT2B PKD1	9.76e-04	16	101	2	22677559
Pubmed	Expression dynamics of metalloproteinases during mandibular bone formation: association with Myb transcription factor.	MMP12 MYB	9.76e-04	16	101	2	37701782
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	TRIO KALRN MRC2 KDM1A	1.01e-03	151	101	4	17043677
Pubmed	Overactivation of hedgehog signaling alters development of the ovarian vasculature in mice.	CYP17A1 DHH	1.10e-03	17	101	2	22402963
Pubmed	Polymorphisms revealed by PCR with single, short-sized, arbitrary primers are reliable markers for mouse and rat gene mapping.	CA2 MYB	1.10e-03	17	101	2	1617216
Pubmed	Aberrant and constitutive expression of FOXL2 impairs ovarian development and functions in mice.	CYP17A1 DHH	1.10e-03	17	101	2	32945847
Pubmed	Structural and functional consequences of NEDD8 phosphorylation.	HDAC6 HSPH1 USP3	1.13e-03	70	101	3	34642328
Pubmed	Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development.	CYP17A1 DHH	1.24e-03	18	101	2	23087174
Pubmed	Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs.	HSPG2 CA3	1.24e-03	18	101	2	12571105
Pubmed	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	RNF213 CELSR2	1.38e-03	19	101	2	23118302
Pubmed	Transcription arrest relief by S-II/TFIIS during gene expression in erythroblast differentiation.	CA2 MYB	1.38e-03	19	101	2	19210546
Pubmed	Genome-wide identification of FOXL2 binding and characterization of FOXL2 feminizing action in the fetal gonads.	CYP17A1 DHH	1.38e-03	19	101	2	30212841
Pubmed	Conditional ablation of Gata4 and Fog2 genes in mice reveals their distinct roles in mammalian sexual differentiation.	CYP17A1 DHH	1.53e-03	20	101	2	21385577
Pubmed	Characterization of the proteins of isolated human platelet alpha-granules. Evidence for a separate alpha-granule-pool of the glycoproteins IIb and IIIa.	BRPF3 WDR1	1.69e-03	21	101	2	6457647
Pubmed	Notch signaling maintains Leydig progenitor cells in the mouse testis.	CYP17A1 DHH	1.69e-03	21	101	2	18927153
Pubmed	Regulation of the endosomal SNX27-retromer by OTULIN.	HDAC6 USP3	1.69e-03	21	101	2	31541095
Pubmed	Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.	HSPH1 LARP4B CELSR2	1.85e-03	83	101	3	9039502
Pubmed	TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway.	CYP17A1 DHH	1.86e-03	22	101	2	35906245
Pubmed	Matrix metalloproteinases.	MMP25 MMP12	1.86e-03	22	101	2	10419448
Pubmed	Next-generation sequencing to generate interactome datasets.	AOC1 ILK CES1 PKP4 TSSC4 DPPA4 SPOCK3 KDM1A PRRC2B MORN3	1.87e-03	1147	101	10	21516116
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	GPRASP1 TRIO KALRN PKP4 SHANK3 CELSR2 WDR1 KDM1A PRRC2B	1.99e-03	963	101	9	28671696
Cytoband	8q21.2	CA13 CA1 CA3	9.76e-06	19	101	3	8q21.2
Cytoband	Ensembl 112 genes in cytogenetic band chr8q21	CA13 CA1 CA2 CA3	8.82e-04	192	101	4	chr8q21
Cytoband	1q21.3	FLG TARS2 RPTN	2.24e-03	117	101	3	1q21.3
GeneFamily	Carbonic anhydrases	CA13 CA1 CA2 CA3 CA5A CA6	6.82e-11	18	74	6	460
GeneFamily	Endogenous ligands\|Matrix metallopeptidases	MMP21 MMP25 MMP12	1.25e-04	24	74	3	891
GeneFamily	EF-hand domain containing\|S100 fused type protein family	FLG RPTN	3.42e-04	7	74	2	1350
GeneFamily	Ankyrin repeat domain containing	ILK ESPNL ANKRD6 SHANK3 ANKDD1B	3.14e-03	242	74	5	403
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_MEMP\|lymph-node_spleen / Manually curated celltypes from each tissue	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 CA1 MYB	1.57e-07	176	101	7	23a8ec42ebd42c539865a12d09773af90f3f8848
ToppCell	3'_v3-blood-Hematopoietic_progenitors-Progenitor_Erythro-Mega\|blood / Manually curated celltypes from each tissue	HSPG2 DPPA4 CPXM1 NME4 CA1 CA2 MYB	2.28e-07	186	101	7	59c115bbbb4bca4ad80be1809d8a0422b8438ea3
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_Erythro-Mega\|bone_marrow / Manually curated celltypes from each tissue	HSPG2 DPPA4 CPXM1 NME4 CA1 CA2 MYB	2.83e-07	192	101	7	cbc304c704e8524eee24a1619d0fbb2cf96c4976
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRUNE2 ILK CES1 WNT2B PCSK7 WDR1 NME4	2.93e-07	193	101	7	a402e736440684ebe123673b6b0c6fcd8fa057b2
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-hematologic\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DPPA4 CPXM1 NME4 CA1 CA2 MYB HSP90AB3P	3.25e-07	196	101	7	9ac60ce1d5a92e1876fe5b96c3fe3536d7b3276d
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-hematologic-hematopoietic_progenitor\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DPPA4 CPXM1 NME4 CA1 CA2 MYB HSP90AB3P	3.25e-07	196	101	7	412fc4778ff30c2a9d21e92248eceb83dd522445
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	GPRASP1 BRPF3 CES1 MRC2 PLD1 CA2	2.42e-06	169	101	6	b66ffc2b2b6bfcc3a6e639d9d31d3de95f4a94e1
ToppCell	severe_COVID-19-HSPC\|severe_COVID-19 / disease group, cell group and cell class (v2)	HSPG2 LCT SHANK3 DPPA4 CPXM1 MYB	2.87e-06	174	101	6	6d35bacf073537b272ff821e604c899fb9ce6a7c
ToppCell	severe_COVID-19-HSPC\|World / disease group, cell group and cell class (v2)	HSPG2 LCT SHANK3 DPPA4 CPXM1 MYB	3.17e-06	177	101	6	289f6aed6f054b04b01659434d8c8b467d1bf5dd
ToppCell	COVID-19_Mild-Hematopoietic_SC-HSPC\|COVID-19_Mild / Disease group, lineage and cell class	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	3.38e-06	179	101	6	19fcf48f5e02e4cb2b328efb4502f337e1282f72
ToppCell	PBMC-Mild-Hematopoietic-HSPC-HSPC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	3.38e-06	179	101	6	4bb2debfc9e9f258cd38e797ef160bd440aad6af
ToppCell	PBMC-Mild-Hematopoietic-HSPC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	3.38e-06	179	101	6	2f690f933bf6b99abeb31766e0b22bdbe36c1ba0
ToppCell	PBMC-Mild-Hematopoietic-HSPC-HSPC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	3.38e-06	179	101	6	3e2c937369b8190fd5d5a31689d029e6e89fb5e2
ToppCell	COVID-19_Mild-Hematopoietic_SC\|COVID-19_Mild / Disease group, lineage and cell class	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	3.38e-06	179	101	6	50a073166e34bcfa52a62c4dafb3aef724e0fa8e
ToppCell	PBMC-Mild-Hematopoietic-HSPC-HSPC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	3.60e-06	181	101	6	e7f7b519c2a01c15f26df11ec9b434c0d1630c7a
ToppCell	PBMC-Mild-Hematopoietic-HSPC-HSPC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	3.60e-06	181	101	6	54a19cf6a3b752e2391feb8b316bebee0e602d17
ToppCell	PBMC-Mild-Hematopoietic-HSPC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	3.60e-06	181	101	6	5b84625b1d3737708001b64f6da9360330d39a27
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRUNE2 ILK CES1 PCSK7 NME4 CA3	3.72e-06	182	101	6	7b86703559438e2d5ef3dad963ee0d772513f313
ToppCell	COVID-19_Severe-Hematopoietic_SC-HSPC\|COVID-19_Severe / Disease group, lineage and cell class	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	3.84e-06	183	101	6	4146b1c0e5f76d25226745abfa28f77127a444fc
ToppCell	COVID-19_Severe-Hematopoietic_SC\|COVID-19_Severe / Disease group, lineage and cell class	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	3.84e-06	183	101	6	92aab7ce65aca17988bc2add4ff9fb8384e2c21b
ToppCell	PBMC-Severe-Hematopoietic-HSPC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	3.96e-06	184	101	6	a6169613c6493b947a176493f542368bfa935dab
ToppCell	PBMC-Severe-Hematopoietic-HSPC-HSPC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	3.96e-06	184	101	6	51d0447699e3b8f01abbde83f26b748bc9f3c723
ToppCell	PBMC-Severe-Hematopoietic-HSPC-HSPC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	3.96e-06	184	101	6	f7b0bb45a9055ab34e98b251217f6ec38c75ca22
ToppCell	PBMC-Severe-Hematopoietic-HSPC-HSPC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	3.96e-06	184	101	6	cc01c19180861f491a8dc16d60fabd1215fc4525
ToppCell	PBMC-Severe-Hematopoietic-HSPC-HSPC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	3.96e-06	184	101	6	492c680f0769ba4e651d09c2e8e5d5d271ed08aa
ToppCell	PBMC-Severe-Hematopoietic-HSPC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	3.96e-06	184	101	6	26edbf84216538b80f1ffcc079ee6e385a71fbf9
ToppCell	COVID-19_Severe-HSPC\|World / disease group, cell group and cell class	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	4.62e-06	189	101	6	555c0b13f1508b9e3712b36d77144e73e828bc76
ToppCell	COVID-19_Severe-HSPC\|COVID-19_Severe / disease group, cell group and cell class	HSPG2 SHANK3 DPPA4 SPOCK3 CPXM1 MYB	4.62e-06	189	101	6	96015439971e2e5b8d6294ca5a6b873c7774e925
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Sla_(Layer6a)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FLG WNT2B ESPNL ADAD2	5.96e-06	52	101	4	c134eb63bd1969af2af7f8de5989e19063533865
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Sla_(Layer6a)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FLG WNT2B ESPNL ADAD2	5.96e-06	52	101	4	14971277db09343d668e4f5a82ca2b6a92326251
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-hematopoietic_progenitor\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DPPA4 CPXM1 NME4 CA1 CA2 MYB	6.03e-06	198	101	6	d5996bd3756fcd4d5866006da2ecd923f0f25427
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DPPA4 CPXM1 NME4 CA1 CA2 MYB	6.03e-06	198	101	6	8be58e41ae7870d268e7ce5ab937769e2ecb60d9
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CES1 ATP10B NR6A1 DMBT1 CA1 CA3	6.21e-06	199	101	6	527aae1d9d37a50deefc01fc0c064a53673681bd
ToppCell	Sepsis-Bac-SEP-Myeloid-cDC1\|Bac-SEP / Disease, condition lineage and cell class	CNFN CD1C MRC2 ANKDD1B CPXM1 NME4	6.39e-06	200	101	6	cd381644fd8b8674a017d267bfbb00f2668294ae
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Hpcal-Igfbp4_(Entorhinal_cortex)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CNFN ESPNL GPRC6A NEU2	1.06e-05	60	101	4	604f050cafb1c2378a6957831833d47ff555c1fd
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Hpcal-Igfbp4_(Entorhinal_cortex)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CNFN ESPNL GPRC6A NEU2	1.06e-05	60	101	4	831efcadd99ad04d37cd763ecf8aaa439b09046d
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor-common_myeloid_progenitor\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HSPG2 SHANK3 DPPA4 CPXM1 MYB	1.52e-05	137	101	5	6d90da42dcc06aa895f920218055068f3c76d57d
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNFN CSMD3 CRB1 DPPA4 DMBT1	2.00e-05	145	101	5	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	mild_COVID-19_(asymptomatic)-CD8+_T_naive\|World / disease group, cell group and cell class (v2)	CELSR2 MRC2 SCNN1D CA5A CA6	2.51e-05	152	101	5	f944743f40ff6ed3a7a096dd53e12d3526c67c4d
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD1C ZNF469 MRC2 MMP12 CA2	2.76e-05	155	101	5	d76a0f99ec35560d18820f9c92b69364ef2250e3
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PATL1 NR6A1 CELSR2 ANKDD1B MMP12	3.31e-05	161	101	5	3f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Chrm2_(Cerebellum_basket_cells_4)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MAGEL2 LCT POLQ SPATA25	3.32e-05	80	101	4	54f520cca126810510479fbeade2e3f66fb5dd1b
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Chrm2_(Cerebellum_basket_cells_4)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MAGEL2 LCT POLQ SPATA25	3.32e-05	80	101	4	ce38ea123853a1e1082a033fb779b63ea440661d
ToppCell	remission-HSPC\|World / disease stage, cell group and cell class	HSPG2 CRYBA4 DPPA4 CPXM1 MYB	3.83e-05	166	101	5	d269ee6f7adb55b05dcb5eaea96629ccb0b2d6e3
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SHANK3 DPPA4 SPOCK3 CPXM1 MYB	4.29e-05	170	101	5	5bb577e2c4bd275fbe4ee23ff8c007b2fcb90e56
ToppCell	COVID-19_Convalescent-Hematopoietic_SC\|COVID-19_Convalescent / Disease group, lineage and cell class	HSPG2 CRYBA4 DPPA4 CPXM1 MYB	4.29e-05	170	101	5	8a73d5334eed1cd9fdcc3ebeae0bdf9f945c228a
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC-HSPC\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSPG2 CRYBA4 DPPA4 CPXM1 MYB	4.41e-05	171	101	5	2031797d579ce373921affad70da6e50eec13664
ToppCell	remission-HSPC\|remission / disease stage, cell group and cell class	HSPG2 CRYBA4 DPPA4 CPXM1 MYB	4.41e-05	171	101	5	41b424e58470a2fc25632aea50a37c7c5ea17645
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC-HSPC-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSPG2 CRYBA4 DPPA4 CPXM1 MYB	4.41e-05	171	101	5	a4e13b304ef414722ffdc06560deeab41785e956
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSPG2 CRYBA4 DPPA4 CPXM1 MYB	4.41e-05	171	101	5	172db31a37b72fb87fe5f0f79da51866b90dd1ad
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HSPG2 WNT2B SHANK3 DHH PTPRG	4.41e-05	171	101	5	1597459c971d6befa991d59dc66b41b6a522f797
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC-HSPC-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HSPG2 CRYBA4 DPPA4 CPXM1 MYB	4.54e-05	172	101	5	8fd3db757d54949bd583d5f0eadf63a32342cb9d
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	HSPG2 CRYBA4 DPPA4 CPXM1 MYB	4.54e-05	172	101	5	da78f7a71b7f05c5c484c9ed19ba37c55d35e870
ToppCell	mild-Others-CD34+_GATA2+_cells\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	HSPG2 SHANK3 DPPA4 CPXM1 MYB	4.54e-05	172	101	5	379f6f271e653d5e404851e51a189bd582bb0f43
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC-HSPC\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	HSPG2 CRYBA4 DPPA4 CPXM1 MYB	4.54e-05	172	101	5	382cb5fea099110eb026a8bba6cf4c28763ea52f
ToppCell	Bac-SEP-Myeloid-cDC1\|Bac-SEP / Disease, Lineage and Cell Type	CNFN CD1C MRC2 CPXM1 NME4	4.66e-05	173	101	5	f88269327441858ddb8c49b9dd619b76fd53b1da
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors\|lymph-node_spleen / Manually curated celltypes from each tissue	SHANK3 DPPA4 CPXM1 CA1 MYB	4.79e-05	174	101	5	6d9bdf4d28ff8ebb66ffd1ccdd6a4fe9440a83f3
ToppCell	droplet-Lung-18m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 MAN1C1 RENBP KIF19 MMP12	4.79e-05	174	101	5	33e5903adb746f693433bdca11a75c508bbf50c0
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SHANK3 DPPA4 SPOCK3 CPXM1 MYB	4.79e-05	174	101	5	66df78280f657978c4a568010ae7d7943869af90
ToppCell	droplet-Lung-18m-Hematologic-myeloid-interstitial_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 MAN1C1 RENBP KIF19 MMP12	4.79e-05	174	101	5	ca0c2f42544092848541863c4a47b334e6828b8a
ToppCell	Healthy-RBC\|World / disease group, cell group and cell class	CRB1 LOXHD1 CA1 CA2 CA3	5.20e-05	177	101	5	2ce41e37fa7139c7bd2b464bd86c5601dc501515
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CA13 CA1 CA2 CA3 MYB	5.20e-05	177	101	5	b75f519d72611b293d9684f7dcfb1b70fbf54a90
ToppCell	Healthy-RBC\|Healthy / disease group, cell group and cell class	CRB1 LOXHD1 CA1 CA2 CA3	5.20e-05	177	101	5	945d72ab52efa9a9468daace9f9ec676a891d963
ToppCell	control-Others-CD34+_GATA2+_cells\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	HSPG2 SHANK3 DPPA4 CPXM1 MYB	5.34e-05	178	101	5	2120bd3e099b0b271bf079db9827a2f3eee2f909
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CA13 CA1 CA2 CA3 MYB	5.34e-05	178	101	5	f332c7a96844abecf05ca057480fbea9296688a2
ToppCell	10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-pDC_progenitor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	AOC1 ZNF469 FOXRED2 SPOCK3 NME4	5.34e-05	178	101	5	dff7a59e53a7329212689ca234931ed4a1b67eee
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRUNE2 ILK CES1 SPOCK3 CA3	5.48e-05	179	101	5	e860dca9b28ac5af61804bfd729cd39257cdb352
ToppCell	severe-Others-CD34+_GATA2+_cells\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	HSPG2 SHANK3 DPPA4 CPXM1 MYB	5.48e-05	179	101	5	dd789a1b7327d6f9ed5272f3eb54bd43f7ae8d78
ToppCell	PBMC-Control-Hematopoietic-HSPC-HSPC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HSPG2 SHANK3 DPPA4 CPXM1 MYB	5.93e-05	182	101	5	6497eeafb2b137e70261ec0314782831892a940d
ToppCell	Control-Hematopoietic_SC-HSPC\|Control / Disease group, lineage and cell class	HSPG2 SHANK3 DPPA4 CPXM1 MYB	5.93e-05	182	101	5	14e347c0e6444410f1948851407bb18c706569f4
ToppCell	Control-Hematopoietic_SC\|Control / Disease group, lineage and cell class	HSPG2 SHANK3 DPPA4 CPXM1 MYB	5.93e-05	182	101	5	43243c6bae2ac7fa3fd1f193a17f61ee4d938ea9
ToppCell	PBMC-Control-Hematopoietic-HSPC-HSPC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSPG2 SHANK3 DPPA4 CPXM1 MYB	5.93e-05	182	101	5	d0ebf2f0d5370458ab81485a0017c311077133d5
ToppCell	PBMC-Control-Hematopoietic-HSPC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	HSPG2 SHANK3 DPPA4 CPXM1 MYB	5.93e-05	182	101	5	bd1626261803324084fafca2f6665b50854e7fae
ToppCell	healthy_donor-Myeloid-Monocytic-SC_&_Eosinophil\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SHANK3 MMP25 DPPA4 CPXM1 MYB	5.93e-05	182	101	5	6bd6c32c48fecd6d03ac8a09e405b3b99bdc12ae
ToppCell	PBMC-Control-Hematopoietic-HSPC-HSPC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSPG2 SHANK3 DPPA4 CPXM1 MYB	5.93e-05	182	101	5	2a6d1246bfb5899a0861c7f2f8fb9b43b0df8acc
ToppCell	PBMC-Control-Hematopoietic-HSPC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSPG2 SHANK3 DPPA4 CPXM1 MYB	5.93e-05	182	101	5	918286422b3eab32d962b49aa07b1b9512e51d9d
ToppCell	PBMC-Control-Hematopoietic-HSPC-HSPC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	HSPG2 SHANK3 DPPA4 CPXM1 MYB	5.93e-05	182	101	5	0d9b8c900da8cbae9cde72aecd4026b1ac2bbd67
ToppCell	hematopoetic_progenitors-CD34+_MEP_2\|World / Lineage and Cell class	HSPG2 CRB1 CPXM1 PLD1 MYB	5.93e-05	182	101	5	a7e7aa10f14111a6c7ba22e0f1668dcaa124714d
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CA13 CA1 CA2 CA3 MYB	6.09e-05	183	101	5	f8b636391f752e379a5c5575fd898bdf0907a3b8
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega-Erythrocytic_early\|lymph-node_spleen / Manually curated celltypes from each tissue	NME4 CA1 CA2 CA3 MYB	6.09e-05	183	101	5	0d56e16d4868c752c7557acec212029eb469ed05
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CA13 CA1 CA2 CA3 MYB	6.25e-05	184	101	5	ae0a77e3e520a246b17776bb19503519636b02ee
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP\|bone_marrow / Manually curated celltypes from each tissue	SHANK3 DPPA4 CPXM1 NME4 MYB	6.25e-05	184	101	5	b81a2a95944cee8fec13d63dc0d95496e67aa937
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like\|lymph-node_spleen / Manually curated celltypes from each tissue	MMP25 DPPA4 SPOCK3 MRC2 CA2	6.25e-05	184	101	5	d97471a4fe17cba6880ccf1a04cc00c741558124
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	MMP25 DPPA4 SPOCK3 MRC2 CA2	6.25e-05	184	101	5	479e60f76c191253e23699c9dd7ef7efc08c59ad
ToppCell	COVID-19_Moderate-HSPC\|World / disease group, cell group and cell class	SHANK3 DPPA4 SPOCK3 CPXM1 MYB	6.25e-05	184	101	5	ccc93babe1fcdeb66b78e1d8414357877a7c45bd
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NR6A1 ANKRD6 TMEM132D CA1 CA3	6.41e-05	185	101	5	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HSPG2 WNT2B SHANK3 DHH PTPRG	6.41e-05	185	101	5	a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCell	COVID-19_Moderate-HSPC\|COVID-19_Moderate / disease group, cell group and cell class	SHANK3 DPPA4 SPOCK3 CPXM1 MYB	6.41e-05	185	101	5	cacc6ab5f26f6c803894567fb838ea06eaa7efe5
ToppCell	(8)_CD34_progenitor\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	HSPG2 DPPA4 CPXM1 CA1 MYB	6.57e-05	186	101	5	943c604a7cd873faf510096d094100512ba2d6bc
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CA13 CA1 CA2 CA3 MYB	6.57e-05	186	101	5	77592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCell	(8)_CD34_progenitor\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	HSPG2 DPPA4 CPXM1 CA1 MYB	6.57e-05	186	101	5	e69a986b8618effd61875fda528a2e44aab11868
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	HSPG2 KALRN PKP4 SHANK3 PTPRG	6.74e-05	187	101	5	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CA13 CA1 CA2 CA3 MYB	6.91e-05	188	101	5	8268574584e5fb869a6cb8bbd7135cd7454a6a25
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CA13 CA1 CA2 CA3 MYB	6.91e-05	188	101	5	4544552ebd67e9eb3e40d8511bb2b03a6e1178f8
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	TRIO HSPH1 ZNF469 MRC2 SPATA25	6.91e-05	188	101	5	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	MAGEL2 SHANK3 CD1C DHH CPXM1	6.91e-05	188	101	5	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)\|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DPPA4 CPXM1 POLQ CA1 MYB	6.91e-05	188	101	5	557a0ac069a6ff4e687cac032f64170b9b247165
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CA13 CA1 CA2 CA3 MYB	6.91e-05	188	101	5	3139540a656c0436b2123ea50741ff8d00112165
ToppCell	Endothelial-endothelial_cell_of_artery\|World / Lineage, Cell type, age group and donor	HSPG2 WNT2B SHANK3 DHH PTPRG	7.09e-05	189	101	5	fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CA13 CA1 CA2 CA3 MYB	7.09e-05	189	101	5	222e67d3fd106c43b0cae6538dddeaa7be1f759f
Computational	AA biosynthesis.	PTPRG CA1 CA2 CA3 CA5A CA6	2.69e-10	18	56	6	MODULE_354
Computational	Metal ion (zinc) binding.	PTPRG PAM MMP12 CA2 CA5A	3.33e-06	45	56	5	MODULE_280
Computational	Genes in the cancer module 295.	PTPRG CA2 CA5A CA6	3.70e-06	21	56	4	MODULE_295
Computational	Genes in the cancer module 294.	CA2 CA5A CA6	1.03e-04	18	56	3	MODULE_294
Computational	Nitrogen metabolism.	CA2 CA5A CA6	2.84e-04	25	56	3	MODULE_343
Computational	Metal / Ca ion binding.	AOC1 CRB1 PAM MMP12 CA2	6.20e-04	133	56	5	MODULE_324
Drug	aminozolamide	CA13 CA1 CA2 CA3 CA5A	8.19e-11	8	100	5	CID000093505
Drug	L-662,583	CA13 CA1 CA2 CA3 CA5A	8.19e-11	8	100	5	CID003082977
Drug	L-643,799	CA13 CA1 CA2 CA3 CA5A	8.19e-11	8	100	5	CID000121595
Drug	sezolamide	CA13 CA1 CA2 CA3 CA5A	8.19e-11	8	100	5	CID000060692
Drug	sulthiame	CA13 CA1 CA2 CA3 CA5A CA6	1.60e-10	19	100	6	CID000005356
Drug	qassa	CA13 CA1 CA2 CA3 CA5A	1.84e-10	9	100	5	CID003082191
Drug	6-hydroxyethoxzolamide	CA13 CA1 CA2 CA3 CA5A	1.84e-10	9	100	5	CID000094706
Drug	I-7B	CA13 CA1 CA2 CA5A	3.50e-10	4	100	4	CID000067136
Drug	Prontosil	CA13 CA1 CA2 CA3 CA5A	3.66e-10	10	100	5	CID000066895
Drug	metanilamide	CA13 CA1 CA2 CA3 CA5A	3.66e-10	10	100	5	CID000007377
Drug	1,3-benzenedisulfonamide	CA13 CA1 CA2 CA3 CA5A	3.66e-10	10	100	5	CID003090044
Drug	brinzolamide	CA13 CA1 CA2 CA3 MYB CA5A CA6	4.22e-10	40	100	7	CID000068844
Drug	dichlorphenamide	CA13 CA1 CA2 CA3 CA5A CA6	5.86e-10	23	100	6	CID000003038
Drug	Cl 13850	CA13 CA1 CA2 CA3 CA5A	6.68e-10	11	100	5	CID000159459
Drug	cobalt phosphate	CA13 CA1 CA2 CA3 CA5A	6.68e-10	11	100	5	CID000061615
Drug	Tio-urasin	CA13 CA1 CA2 CA3 CA5A	6.68e-10	11	100	5	CID000084724
Drug	hydroflumethiazide	CA13 CA1 CA2 CA3 CA5A	1.14e-09	12	100	5	CID000003647
Drug	AC1L1GXT	CA13 MMP21 MMP25 MMP12 CA1 CA2 CA3 CA5A	1.24e-09	74	100	8	CID000003890
Drug	methazolamide	CA13 CA1 CA2 CA3 CA5A CA6	1.32e-09	26	100	6	CID000004100
Drug	mafenide acetate	CA13 CA1 CA2 CA3 CA5A	1.85e-09	13	100	5	CID000003998
Drug	chlorzolamide	CA13 CA1 CA2 CA3 CA5A	1.85e-09	13	100	5	CID000165323
Drug	Fg 400	CA13 CA1 CA2 CA3 CA5A	1.85e-09	13	100	5	CID000012443
Drug	benzolamide	CA13 CA1 CA2 CA3 CA5A CA6	2.15e-09	28	100	6	CID000018794
Drug	cobalt;sulfide	CA13 CA1 CA2 CA3 CA5A	2.87e-09	14	100	5	CID000159453
Drug	sulfamide	HDAC6 CA13 CA1 CA2 CA3 CA5A	4.15e-09	31	100	6	CID000082267
Drug	1gaf	CA13 PCSK7 PAM CA1 CA2 CA3 CA5A	4.95e-09	56	100	7	CID000444283
Drug	dimethadione	CA13 PAM CA1 CA2 CA3 CA5A	5.10e-09	32	100	6	CID000003081
Drug	orthanilamide	CA13 CA1 CA2 CA5A	5.22e-09	6	100	4	CID000072894
Drug	triamterene	CA13 SCNN1D CA1 CA2 CA3 CA5A CA6	6.38e-09	58	100	7	CID000005546
Drug	ebrotidine	CA13 CA1 CA2 CA3 CA5A CA6	7.51e-09	34	100	6	CID000065869
Drug	metolazone	CA13 CA1 CA2 CA3 CA5A	8.77e-09	17	100	5	CID000004170
Drug	zonisamide	CA13 SCNN1D CA1 CA2 CA3 CA5A CA6	1.03e-08	62	100	7	CID000005734
Drug	apraclonidine	CA13 CA1 CA2 CA3 CA5A	1.21e-08	18	100	5	CID000002216
Drug	tauroursocholate	CES1 LDHAL6B CA13 LCT PCSK7 CA1 CA2 CA3 CA5A	1.66e-08	146	100	9	CID000005246
Drug	bendrofluazide	CA13 CA1 CA2 CA3 CA5A CA6	1.79e-08	39	100	6	CID000002315
Drug	indisulam	CA13 CA1 CA2 CA3 CA5A CA6	1.79e-08	39	100	6	CID000216468
Drug	ethoxzolamide	CA13 CA1 CA2 CA3 CA5A CA6	2.10e-08	40	100	6	CID000003295
Drug	metronidazole	CA13 LCT CA1 CA2 CA3 CA5A CA6	2.20e-08	69	100	7	CID000004173
Drug	AC1LCVB4	CA13 CA1 CA2 CA3 CA5A	2.84e-08	21	100	5	CID000656627
Drug	AABSSN	CA13 CA1 CA2 CA3 CA5A	3.67e-08	22	100	5	CID005464134
Drug	potassium cyanate	CA13 CA1 CA2 CA3 CA5A	5.88e-08	24	100	5	CID011378442
Drug	valdecoxib	CA13 RENBP CA1 CA2 CA3 CA5A	7.40e-08	49	100	6	CID000119607
Drug	p-nitrophenyl acetate	CES1 LYPLA2 CA13 CA1 CA2 CA3 CA5A	8.05e-08	83	100	7	CID000013243
Drug	4-hydroxymethylbenzenesulfonamide	CA1 CA2 CA5A	8.22e-08	3	100	3	CID010081162
Drug	6-hydroxy-1,3-benzothiazole-2-sulfonamide	CA1 CA2 CA5A	8.22e-08	3	100	3	CID006852129
Drug	4-hydrazinobenzenesulfonamide	CA1 CA2 CA5A	8.22e-08	3	100	3	CID000078105
Drug	I7C	CA1 CA2 CA5A	8.22e-08	3	100	3	CID000069561
Drug	4-(2-aminopyrimidin-4-yl-amino)-benzenesulfonamide	CA1 CA2 CA5A	8.22e-08	3	100	3	CID000031035
Drug	AC1Q551A	CA1 CA2 CA5A	8.22e-08	3	100	3	CID011206245
Drug	AC1NA7ER	CA1 CA2 CA5A	8.22e-08	3	100	3	CID004422372
Drug	Benzolamide	CA1 CA2 CA3	8.22e-08	3	100	3	ctd:D001574
Drug	Ethoxzolamide	CA1 CA2 CA3	8.22e-08	3	100	3	ctd:D005016
Drug	4-(2-aminoethyl)benzenesulfonamide	CA1 CA2 CA5A	8.22e-08	3	100	3	CID000169682
Drug	CTK1B7592	CA1 CA2 CA5A	8.22e-08	3	100	3	CID009998322
Drug	4-(2-hydroxyethyl)benzenesulfonamide	CA1 CA2 CA5A	8.22e-08	3	100	3	CID010375558
Drug	AC1NQARZ	CA1 CA2 CA5A	8.22e-08	3	100	3	CID005172475
Drug	sulpiride (SLP	CA1 CA2 CA5A	8.22e-08	3	100	3	CID003018597
Drug	STX64	CES1 CA1 CA2 CA5A	1.13e-07	11	100	4	CID005287541
Drug	indapamide	CA13 CA1 CA2 CA3 CA5A CA6	1.20e-07	53	100	6	CID000003702
Drug	sulfonamide	CA13 CA1 CA2 CA3 CA5A CA6	1.34e-07	54	100	6	CID000005333
Drug	sulfamate	CES1 CA13 CA1 CA2 CA3 CA5A	1.34e-07	54	100	6	CID000005987
Drug	Zinc chromate hydroxide	CA13 CA1 CA2 CA3 CA5A	1.61e-07	29	100	5	CID000027567
Drug	thiadiazole	CA13 CA1 CA2 CA3 CA5A	1.61e-07	29	100	5	CID000067518
Drug	AC1L9LQQ	CA13 PCSK7 CA1 CA2 CA3 CA5A	1.87e-07	57	100	6	CID000448224
Drug	AC1L1GEZ	CA13 PCSK7 PLD1 MMP12 CA1 CA2 CA3 CA5A CA6	2.48e-07	200	100	9	CID000003653
Drug	Dantrolene-13C3	CA13 PKD1 MMP12 CA1 CA2 CA3 CA5A CA6	2.53e-07	145	100	8	CID000002951
Drug	benzenesulfonamide	CA13 CA1 CA2 CA3 CA5A	3.18e-07	33	100	5	CID000007370
Drug	MZ-m	CA13 CA1 CA2 CA3 CA5A	3.18e-07	33	100	5	CID000001798
Drug	3-Iodosulfanilamide	CA1 CA2 CA5A	3.28e-07	4	100	3	CID009861037
Drug	NSC-700707	CA1 CA2 CA5A	3.28e-07	4	100	3	CID000134560
Drug	N-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide	CA1 CA2 CA3	3.28e-07	4	100	3	ctd:C439829
Drug	AC1Q511M	CA1 CA2 CA5A	3.28e-07	4	100	3	CID004687472
Drug	3-bromosulfanilamide	CA1 CA2 CA5A	3.28e-07	4	100	3	CID003526523
Drug	PB311	CA1 CA2 CA5A	3.28e-07	4	100	3	CID001502014
Drug	zonisamide	CA1 CA2 CA3 CA5A	3.39e-07	14	100	4	ctd:C022189
Drug	chlorthalidone	CA13 CA1 CA2 CA3 CA5A	5.00e-07	36	100	5	CID000002732
Drug	cetyltrimethylammonium bromide	CA13 CA1 CA2 CA3 CA5A CA6	5.42e-07	68	100	6	CID000002681
Drug	T2755	CA13 SCNN1D CA1 CA2 CA3 CA5A	7.01e-07	71	100	6	CID000005514
Drug	potassium periodate	CA1 CA2 CA5A	8.17e-07	5	100	3	ctd:C037192
Drug	sodium metasilicate	CA1 CA2 CA5A	8.17e-07	5	100	3	ctd:C025349
Drug	Iodates	CA1 CA2 CA5A	8.17e-07	5	100	3	ctd:D007452
Drug	BCECF	CA13 PAM CA1 CA2 CA3 CA5A	8.28e-07	73	100	6	CID004241719
Drug	hydrochlorothiazide	CA13 SCNN1D CA1 CA2 CA3 CA5A CA6	1.01e-06	120	100	7	CID000003639
Drug	topiramate	CYP17A1 PLD1 CA1 CA2 CA3 CA5A	1.05e-06	76	100	6	ctd:C052342
Drug	DB08219	CA13 CA1 CA2 CA3 CA5A	1.40e-06	44	100	5	CID011840966
Drug	choline	CA13 LCT PCSK7 PLD1 MMP12 CA1 CA2 CA3 CA5A CA6	1.48e-06	320	100	10	CID000000305
Drug	EMD 486019	CA1 CA2 CA5A	1.63e-06	6	100	3	CID011245700
Drug	2h15	CA1 CA2 CA5A	1.63e-06	6	100	3	CID010712038
Drug	betaxolol	CA13 CA1 CA2 CA3 CA5A	2.18e-06	48	100	5	CID000002369
Drug	Carbonates	CA1 CA2 CA5A	2.84e-06	7	100	3	ctd:D002254
Drug	sulfamic acid	CA1 CA2 CA5A	2.84e-06	7	100	3	ctd:C005741
Drug	Nitric Acid	CA1 CA2 CA5A	2.84e-06	7	100	3	ctd:D017942
Drug	chloric acid	CA1 CA2 CA5A	2.84e-06	7	100	3	ctd:C022842
Drug	racemic timolol	CA13 CA1 CA2 CA3 CA5A	2.96e-06	51	100	5	CID000005478
Drug	rotigotine patch	CA13 RENBP CA1 CA2 CA3 CA5A	3.45e-06	93	100	6	CID003619466
Drug	1-methylcyclopentanecarboxylic acid	LDHAL6B CA13 CA1 CA2 CA3 CA5A	3.91e-06	95	100	6	CID000138436
Drug	cyanate	CA13 CA1 CA2 CA3 CA5A	4.32e-06	55	100	5	CID000000540
Drug	Bromates	CA1 CA2 CA5A	4.53e-06	8	100	3	ctd:D001959
Drug	Methazolamide	CA1 CA2 CA3	4.53e-06	8	100	3	ctd:D008704
Drug	hydroxyl radicals	AOC1 CES1 CYP4B1 MAN1C1 LYPLA2 CYP17A1 CA13 CPT2 LCT NEU2 PTPRG PAM PLD1 MMP12 CA1 CA2 CA3 CA5A CA6	5.18e-06	1341	100	19	CID000000961
Disease	carbonic anhydrase 1 measurement	CA13 CA1 CA3	3.13e-08	3	94	3	EFO_0020227
Disease	carbonic anhydrase 13 measurement	CA13 CA1	1.00e-05	2	94	2	EFO_0008067
Disease	basophil percentage of granulocytes	LARP4B ZNF469 MYB CA5A	1.46e-04	83	94	4	EFO_0007995
Disease	polycystic liver disease (implicated_via_orthology)	HDAC6 PKD1	2.09e-04	7	94	2	DOID:0050770 (implicated_via_orthology)
Disease	stanniocalcin-1 measurement	LARP4B CELSR2	2.78e-04	8	94	2	EFO_0020753
Disease	prostate adenocarcinoma (is_marker_for)	ILK PAM	4.44e-04	10	94	2	DOID:2526 (is_marker_for)
Disease	unipolar depression	TRIO RNF213 UNC13D CSMD3 CRB1 PTPRG NALCN TMEM132D PKD1 ELP2 PLD1 USP3	4.47e-04	1206	94	12	EFO_0003761
Disease	neuroblastoma	TRIO KALRN MMP25 RPTN	5.27e-04	116	94	4	EFO_0000621
Disease	testosterone measurement	AOC1 CYP4B1 CYP17A1 WNT2B UNC13D CSMD3 THOP1 PTPRG ANKDD1B MMP12 USP3 MORN3	7.30e-04	1275	94	12	EFO_0004908
Disease	Connective Tissue Diseases	ZNF469 PKD1	7.65e-04	13	94	2	C0009782
Disease	serum metabolite measurement	MAGEL2 AOC1 TRIO CYP4B1 CPT2 LARP4B CELSR2 SPOCK3 ELP2 WDR1	8.62e-04	945	94	10	EFO_0005653
Disease	Pneumoconiosis	CA1 CA3	8.91e-04	14	94	2	C0032273
Disease	Bagassosis	CA1 CA3	8.91e-04	14	94	2	C0004681
Disease	polycystic kidney disease (implicated_via_orthology)	HDAC6 PKD1	8.91e-04	14	94	2	DOID:0080322 (implicated_via_orthology)
Disease	unipolar depression, cognitive function measurement	DCAF6 CPXM1	1.03e-03	15	94	2	EFO_0003761, EFO_0008354
Disease	basophil percentage of leukocytes	RSBN1 LARP4B ZNF469 MYB CA5A	1.10e-03	243	94	5	EFO_0007992
Disease	Abdominal Aortic Aneurysm	PKP4 CELSR2 HSP90AB3P	1.35e-03	68	94	3	EFO_0004214

Protein segments in the cluster

Peptide	Gene	Start	Entry
VPHSGWNNSSFDDDH	PKP4	666	Q99569
EKVEFHWGHSNGSAG	PTPRG	146	P23470
CHLLGFTHGTEAEWQ	YBEY	121	P58557
RQFHLHWGSSDDHGS	CA3	91	P07451
GDEHSRGNWGHLDQV	CES1	181	P23141
GWLEFSGQQLHDCHG	ADAD2	271	Q8NCV1
NGHEVFLQWSADHGN	CSMD3	2541	Q7Z407
LLFHSHADQDDWEGG	CFAP46	1116	Q8IYW2
FSVHGNIINGADWHT	CPXM1	556	Q96SM3
DTDGWVHLQFHAGQA	DPPA4	241	Q7L190
GGAFKQTSDGHWAHV	BRPF3	276	Q9ULD4
VIFHRGDHVWDGNSF	PAM	526	P19021
LHWGSADDHGSEHIV	CA13	96	Q8N1Q1
DGDWHHAQLALGASG	CELSR2	1696	Q9HCU4
SGSDCGHIFIWDRHT	DCAF6	736	Q58WW2
NDEQSGDGSRHSWSH	FLG	3491	P20930
VDHGSTDAGHWAVEQ	AOC1	221	P19801
HFHWGGASSEISGSE	CA6	111	P23280
GAVGHSIWNGTFEEH	ATP10B	331	O94823
KDGNTALHEASWHGF	ANKRD6	106	Q9Y2G4
AKDGSTAVHFEHSWG	CPT2	361	P23786
QQGSGHGIAESDWHL	HSPG2	4176	P98160
DAHAAAAALAHSWGA	ERAS	161	Q7Z444
HFDEDEFWTTHSGGT	MMP12	196	P39900
HPISGDTHFDDEETW	MMP25	201	Q9NPA2
TFGSGAVDDDWQEAH	PATL1	36	Q86TB9
WMEHSHDQEHGGFFT	RENBP	36	P51606
FEHLGTHGWEAVRAF	ESPNL	886	Q6ZVH7
HHWQHNGELAEGGAE	MBD6	911	Q96DN6
EDSRGHTLAFHDWQG	MAGEL2	896	Q9UJ55
WESSAGGSFTVHADH	HSP90AB3P	136	Q58FF7
EEEHEVGISTWGGQH	FAM182A	71	Q5T1J6
WNHDSEDTEGVHEVF	HSPH1	406	Q92598
ADGVSAAWEEVAGHH	LARP4B	76	Q92615
EHDNTGLNASWYLDH	LOXHD1	111	Q8IVV2
RAEWVTNEAGFSHSH	PCSK7	446	Q16549
SESCHGWILGEHGDS	LDHAL6B	231	Q9BYZ2
GQEFAHAWRLGDIHF	MMP21	246	Q8N119
WIENHGEAFLSKHTG	KALRN	551	O60229
DHGGWQNESVVDAFL	LCT	506	P09848
QWFHGCTSTGREDGH	MRC2	196	Q9UBG0
KSGNFFCSHHWEGDS	MYB	536	P10242
GSVDLFHVRESGWEH	PSMB11	221	A5LHX3
SVGHTEDAWQSNFLH	FOXRED2	516	Q8IWF2
TDGWNSFHFDAHGDL	GPRC6A	456	Q5T6X5
EGHHVFKAGTGAWQA	KIF19	706	Q2TAC6
DHGRTWARGHFVAQD	NEU2	201	Q9Y3R4
FHWGAVNEGGSEHTV	CA5A	131	P35218
HWDQDDDFEFTGSHL	KDM1A	551	O60341
HGWDSESGTIIFLHN	CD1C	56	P29017
TEGWDEDGHHAQDSL	DHH	126	O43323
FHWGSTNEHGSEHTV	CA1	96	P00915
WGVAFHHAGLTFEER	POLQ	411	O75417
GIAFADSGAHWQLHR	CYP17A1	111	P05093
DLNQGDDHGFSPLHW	ILK	26	Q13418
GNEVGSFHVHSGAWV	CRYBA4	136	P53673
AWVGESFHLNVSGEA	MAN1C1	241	Q9NR34
HGLGDTGHSWADALS	LYPLA2	31	O95372
THWLFGHALEIQETG	CYP4B1	51	P13584
HAASWLIDGIHDSHG	GCNA	596	Q96QF7
GHSSHVTNVAFLWDD	EML2	616	O95834
GAEWLHFASCGEDHT	ELP2	801	Q6IA86
DWDVHHGQGTQFTFD	HDAC6	251	Q9UBN7
LFISHNTSDGEWHFV	CRB1	556	P82279
NGWLTHNCGHSEDAG	DMBT1	316	Q9UGM3
GWLSHNCQHSEDAGV	DMBT1	446	Q9UGM3
NGWLSHNCGHSEDAG	DMBT1	576	Q9UGM3
GWLSHNCGHSEDAGV	DMBT1	1076	Q9UGM3
AWEDSHGSQDGHFVL	SCNN1D	411	P51172
FHLDHGQLFEGFWVD	MORN3	176	Q6PF18
VHFECTGWHDAEDAG	PKD1	2491	P98161
EFEEEANHWSNHGDS	NR6A1	161	Q15406
SSGSEHEDHLESWFG	GPRASP1	296	Q5JY77
AHADHVGQGFDWQST	RSBN1	581	Q5VWQ0
FWHSSTHVLGAAAEQ	TARS2	131	Q9BW92
AVAEEHAWSGEHGEH	PRUNE2	476	Q8WUY3
HAWSGEHGEHFDLFN	PRUNE2	481	Q8WUY3
GGHLAHLLGSDWQVD	TMEM132D	591	Q14C87
EVVLEGSYDGHHWTE	LMF2	466	Q9BU23
QTGVGELHGETRFWH	PLD1	631	Q13393
ELVSWADGGQHSSIH	NME4	171	O00746
LEFTHNHDVGDLTWD	SGSM3	81	Q96HU1
SHDGHINYWDSETGE	WDR1	341	O75083
EGARWEQAHAHTASG	SPATA25	196	Q9BR10
EQWSGNESFREHGHR	ANKDD1B	461	A6NHY2
HWGSLDGQGSEHTVD	CA2	96	P00918
HFHSGDDSQVLAWAL	NCAPD3	656	P42695
HIQGSVGHDWAALTF	CNFN	81	Q9BYD5
RDVGLGAWFEAHIHS	UHRF2	136	Q96PU4
GFHGGLWQSVHIDDL	RNF213	3431	Q63HN8
FDVGDWLESIHLGEH	SHANK3	1671	Q9BYB0
WGSHHGGLQEVEALS	TSSC4	271	Q9Y5U2
WDVSHQPETADTAHG	PRRC2B	871	Q5JSZ5
ISGDFASGDFHEWTD	SPOCK3	386	Q9BQ16
AVAGHQLGLEADGHW	ZNF469	1941	Q96JG9
ESGTHEGLFSHQTWE	ZNF225	91	Q9UK10
ATHEGRWFHFNDSTV	USP3	476	Q9Y6I4
AIWHAFTALDQDHSG	SWAP70	11	Q9UH65
SHGEGLSHWAEEEQG	RPTN	696	Q6XPR3
LLGLAFHHEEGASAW	THOP1	376	P52888
HEVTQHEAGSTSWDG	UNC13D	311	Q70J99
HHDQRGDFDWGGCSD	WNT2B	176	Q93097
WIENHGEAFLSKHTG	TRIO	581	O75962
DVYVSGGHINSHDVW	KLHL35	351	Q6PF15
FHEDAAGGWQLVAVD	NALCN	351	Q8IZF0