Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

HSPG2 COL24A1 FBLN2 EFEMP1 MEGF9 LAMB1 LAMC1 MUC2 MUC5AC

8.66e-08188839GO:0005201
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF711 ZNF705A CTCFL ZNF142 BCL11B HIVEP1 ZNF560 ZNF157 ZNF296 ZNF705EP TRPS1 ZNF705B CREBBP EP300 SMYD3 ZNF705D ZNF551 ZNF705G DNMT3A

6.41e-0614598319GO:0000977
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

1.71e-052832GO:0120300
GeneOntologyMolecularFunctionalpha-L-arabinofuranosidase activity

OTOGL OTOG

1.71e-052832GO:0046556
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

1.71e-052832GO:0044017
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 LRP1B LRP8

3.73e-0516833GO:0005041
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

5.11e-053832GO:0043993
GeneOntologyMolecularFunctionzinc ion binding

TRAF5 HIVEP1 P2RX7 MYCBP2 ZMAT2 TRPS1 TRIM8 PRICKLE2 BIRC2 USP16 CREBBP EP300 ZMYM3

7.44e-058918313GO:0008270
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 LRP1B LRP8

8.73e-0521833GO:0030228
GeneOntologyMolecularFunctiontransition metal ion binding

TRAF5 HIVEP1 P2RX7 MYCBP2 ZMAT2 TRPS1 TRIM8 PRICKLE2 BIRC2 MUC2 USP16 CREBBP EP300 ZMYM3

3.63e-0411898314GO:0046914
GeneOntologyMolecularFunctioncargo receptor activity

LRP1 LRP1B ITGB2 LRP8

4.35e-0485834GO:0038024
GeneOntologyMolecularFunctionbHLH transcription factor binding

FHL2 CREBBP EP300

4.86e-0437833GO:0043425
GeneOntologyMolecularFunctionamyloid-beta binding

HSPG2 LRP1 ITGB2 LRP8

8.66e-04102834GO:0001540
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

FBLN2 LAMC1

1.10e-0312832GO:0030023
GeneOntologyMolecularFunctionstructural molecule activity

HSPG2 COL24A1 FBLN2 EFEMP1 MEGF9 JAG1 LAMB1 LAMC1 MUC2 MUC5AC OTOG

1.12e-038918311GO:0005198
GeneOntologyMolecularFunctionRNA polymerase II intronic transcription regulatory region sequence-specific DNA binding

HIVEP1 SMYD3

1.29e-0313832GO:0001162
GeneOntologyMolecularFunctionglycosphingolipid binding

LAMB1 LAMC1

1.29e-0313832GO:0043208
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

FBLN2 LAMC1

1.50e-0314832GO:0097493
GeneOntologyMolecularFunctiontranscription coactivator activity

TRIM8 BIRC2 USP16 CREBBP EP300 FHL5

1.65e-03303836GO:0003713
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

CREBBP EP300

1.73e-0315832GO:0010484
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF711 ZNF705A CTCFL ZNF142 BCL11B HIVEP1 ZNF560 ZNF157 ZNF705EP TRPS1 ZNF705B ZNF705D ZNF551 ZNF705G

1.93e-0314128314GO:0000981
GeneOntologyMolecularFunctionintronic transcription regulatory region sequence-specific DNA binding

HIVEP1 SMYD3

2.23e-0317832GO:0001161
GeneOntologyMolecularFunctionribosomal small subunit binding

CPEB2 USP16

2.23e-0317832GO:0043024
GeneOntologyMolecularFunctiontranscription coregulator activity

TRIM8 BIRC2 FHL2 USP16 CREBBP EP300 FHL5 DNMT3A

2.32e-03562838GO:0003712
GeneOntologyMolecularFunctionapolipoprotein binding

LRP1 LRP8

3.09e-0320832GO:0034185
GeneOntologyBiologicalProcessarabinose metabolic process

OTOGL OTOG

1.60e-052832GO:0019566
GeneOntologyBiologicalProcessvibrational conductance of sound to the inner ear

OTOGL OTOG

1.60e-052832GO:0055127
GeneOntologyBiologicalProcessL-arabinose metabolic process

OTOGL OTOG

1.60e-052832GO:0046373
GeneOntologyBiologicalProcessN-terminal peptidyl-lysine acetylation

CREBBP EP300

9.55e-054832GO:0018076
GeneOntologyBiologicalProcessaxon guidance

HSPG2 BCL11B MEGF9 MYCBP2 LRP1 LAMB1 LAMC1

1.51e-04285837GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

HSPG2 BCL11B MEGF9 MYCBP2 LRP1 LAMB1 LAMC1

1.55e-04286837GO:0097485
GeneOntologyBiologicalProcesspositive regulation of cellular response to hypoxia

EP300 DNMT3A

1.59e-045832GO:1900039
GeneOntologyBiologicalProcessneuron projection development

HSPG2 BCL11B EFEMP1 ZNF296 MEGF9 MYCBP2 OTOGL PRICKLE2 LRP1 LAMB1 LAMC1 CREBBP EP300 OTOG LRP8

1.68e-0412858315GO:0031175
GeneOntologyCellularComponentextracellular matrix

ADAMTS19 HSPG2 COL24A1 FBLN2 EFEMP1 MEGF9 OTOGL LAMB1 LAMC1 MUC5B MUC2 MUC5AC OTOG

1.79e-066568313GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

ADAMTS19 HSPG2 COL24A1 FBLN2 EFEMP1 MEGF9 OTOGL LAMB1 LAMC1 MUC5B MUC2 MUC5AC OTOG

1.85e-066588313GO:0030312
GeneOntologyCellularComponentlaminin-10 complex

LAMB1 LAMC1

4.66e-053832GO:0043259
GeneOntologyCellularComponentlaminin-1 complex

LAMB1 LAMC1

4.66e-053832GO:0005606
GeneOntologyCellularComponentmucus layer

MUC2 MUC5AC

4.66e-053832GO:0070701
GeneOntologyCellularComponentbasement membrane

HSPG2 EFEMP1 MEGF9 LAMB1 LAMC1

1.26e-04122835GO:0005604
GeneOntologyCellularComponentlaminin complex

LAMB1 LAMC1

6.87e-0410832GO:0043256
GeneOntologyCellularComponentCD40 receptor complex

TRAF5 BIRC2

8.37e-0411832GO:0035631
GeneOntologyCellularComponentsperm head plasma membrane

ADAM21 ADAM29

8.37e-0411832GO:1990913
GeneOntologyCellularComponentGolgi lumen

HSPG2 MUC5B MUC2 MUC5AC

9.37e-04109834GO:0005796
GeneOntologyCellularComponentcollagen-containing extracellular matrix

HSPG2 COL24A1 FBLN2 EFEMP1 MEGF9 LAMB1 LAMC1 MUC2

1.21e-03530838GO:0062023
GeneOntologyCellularComponentprotein complex involved in cell adhesion

LAMB1 LAMC1 ITGB2

1.67e-0359833GO:0098636
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

LAMB1 LAMC1

2.04e-0317832GO:0098637
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

2.51e-052262HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

2.51e-052262HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

2.51e-052262HP:0001042
HumanPhenoDeep philtrum

HSPG2 TRPS1 CREBBP EP300 DNMT3A

3.13e-0575265HP:0002002
HumanPhenoSupernumerary tooth

HSPG2 BCL11B TRPS1 CREBBP EP300

5.74e-0585265HP:0011069
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

7.49e-053262HP:0008752
HumanPhenoPhobia

CREBBP EP300

7.49e-053262HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

7.49e-053262HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

7.49e-053262HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

7.49e-053262HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

7.49e-053262HP:0005895
HumanPhenoFacial hirsutism

CREBBP GNS EP300

9.16e-0518263HP:0009937
HumanPhenoLocalized hirsutism

CREBBP GNS EP300

1.48e-0421263HP:0009889
HumanPhenoTrichiasis

CREBBP EP300

1.49e-044262HP:0001128
HumanPhenoVisceral hemangioma

CREBBP EP300

1.49e-044262HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

1.49e-044262HP:0011087
HumanPhenoWidened distal phalanges

CREBBP EP300

1.49e-044262HP:0006200
HumanPhenoVascular ring

CREBBP EP300

1.49e-044262HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

1.49e-044262HP:0031207
HumanPhenoPapillary cystadenoma of the epididymis

CREBBP EP300

2.48e-045262HP:0009715
HumanPhenoSupernumerary cusp

CREBBP EP300

2.48e-045262HP:0033777
HumanPhenoEpididymal neoplasm

CREBBP EP300

2.48e-045262HP:0030421
HumanPhenoNeoplasm of the nervous system

HSPG2 LRP1 EPCAM CREBBP EP300 DNMT3A

3.53e-04195266HP:0004375
HumanPhenoLarge foramen magnum

CREBBP EP300

3.71e-046262HP:0002700
HumanPhenoShort columella

CREBBP EP300 DNMT3A

3.95e-0429263HP:0002000
HumanPhenoAvascular necrosis of the capital femoral epiphysis

TRPS1 CREBBP EP300

4.37e-0430263HP:0005743
HumanPhenoAbnormality of the ureter

HSPG2 JAG1 TRPS1 TRIM8 CREBBP EP300 ZMYM3 DNMT3A

4.44e-04383268HP:0000069
HumanPhenoDeviated nasal septum

CREBBP EP300

5.18e-047262HP:0004411
HumanPhenoHereditary nonpolyposis colorectal carcinoma

MLH3 EPCAM EP300

5.31e-0432263HP:0006716
HumanPhenoAbnormal branching pattern of the aortic arch

CREBBP EP300 ZMYM3

5.82e-0433263HP:0011587
HumanPhenoVesicoureteral reflux

JAG1 TRPS1 CREBBP EP300 ZMYM3 DNMT3A

6.91e-04221266HP:0000076
DomainEGF-like_dom

HSPG2 FBLN2 EFEMP1 MEGF9 ADAM21 JAG1 LRP1 LAMB1 LAMC1 ADAM29 LRP1B TMEFF2 OTOG LRP8

2.68e-122498014IPR000742
DomainEGF_1

HSPG2 FBLN2 EFEMP1 MEGF9 ADAM21 JAG1 LRP1 LAMB1 LAMC1 ADAM29 LRP1B ITGB2 TMEFF2 LRP8

3.70e-122558014PS00022
DomainEGF-like_CS

HSPG2 FBLN2 EFEMP1 MEGF9 ADAM21 JAG1 LRP1 LAMB1 LAMC1 ADAM29 LRP1B ITGB2 TMEFF2 LRP8

5.07e-122618014IPR013032
DomainEGF_2

HSPG2 FBLN2 EFEMP1 MEGF9 ADAM21 JAG1 LRP1 LAMB1 LAMC1 ADAM29 LRP1B ITGB2 TMEFF2 LRP8

6.22e-122658014PS01186
DomainVWC_out

CRIM1 JAG1 MUC5B MUC2 MUC5AC OTOG

1.32e-1019806SM00215
DomainGrowth_fac_rcpt_

HSPG2 FBLN2 EFEMP1 CRIM1 JAG1 LRP1 LAMB1 LAMC1 LRP1B LRP8

1.23e-091568010IPR009030
DomainEGF_3

HSPG2 FBLN2 EFEMP1 ADAM21 JAG1 LRP1 ADAM29 LRP1B TMEFF2 OTOG LRP8

4.84e-092358011PS50026
DomainEGF

HSPG2 FBLN2 EFEMP1 MEGF9 JAG1 LRP1 LAMB1 LAMC1 LRP1B TMEFF2 LRP8

4.84e-092358011SM00181
DomainVWF_dom

CRIM1 JAG1 MUC5B MUC2 MUC5AC OTOG

2.37e-0842806IPR001007
DomainTIL

MUC5B MUC2 MUC5AC OTOG

1.50e-0712804PF01826
DomainC8

MUC5B MUC2 MUC5AC OTOG

1.50e-0712804PF08742
DomainUnchr_dom_Cys-rich

MUC5B MUC2 MUC5AC OTOG

2.17e-0713804IPR014853
DomainC8

MUC5B MUC2 MUC5AC OTOG

2.17e-0713804SM00832
DomainTIL_dom

MUC5B MUC2 MUC5AC OTOG

3.02e-0714804IPR002919
DomainVWD

MUC5B MUC2 MUC5AC OTOG

5.46e-0716804SM00216
DomainVWF_type-D

MUC5B MUC2 MUC5AC OTOG

5.46e-0716804IPR001846
DomainVWFD

MUC5B MUC2 MUC5AC OTOG

5.46e-0716804PS51233
DomainVWD

MUC5B MUC2 MUC5AC OTOG

5.46e-0716804PF00094
DomainVWC

CRIM1 JAG1 MUC5B MUC2 MUC5AC

5.71e-0738805SM00214
DomainZINC_FINGER_C2H2_2

ZNF711 ZNF705A CTCFL ZNF142 BCL11B HIVEP1 ZNF560 ZNF157 ZNF296 ZMAT2 TRPS1 ZNF705B ZNF705D ZNF551 ZNF705G

8.72e-077758015PS50157
DomainZINC_FINGER_C2H2_1

ZNF711 ZNF705A CTCFL ZNF142 BCL11B HIVEP1 ZNF560 ZNF157 ZNF296 ZMAT2 TRPS1 ZNF705B ZNF705D ZNF551 ZNF705G

9.01e-077778015PS00028
DomainEGF_CA

HSPG2 FBLN2 EFEMP1 JAG1 LRP1 LRP1B LRP8

9.13e-07122807SM00179
DomainEGF-like_Ca-bd_dom

HSPG2 FBLN2 EFEMP1 JAG1 LRP1 LRP1B LRP8

1.02e-06124807IPR001881
DomainZnf_C2H2-like

ZNF711 ZNF705A CTCFL ZNF142 BCL11B HIVEP1 ZNF560 ZNF157 ZNF296 ZMAT2 TRPS1 ZNF705B ZNF705D ZNF551 ZNF705G

1.22e-067968015IPR015880
DomainZnf_C2H2

ZNF711 ZNF705A CTCFL ZNF142 BCL11B HIVEP1 ZNF560 ZNF157 ZNF296 ZMAT2 TRPS1 ZNF705B ZNF705D ZNF551 ZNF705G

1.40e-068058015IPR007087
DomainZnF_C2H2

ZNF711 ZNF705A CTCFL ZNF142 BCL11B HIVEP1 ZNF560 ZNF157 ZNF296 ZMAT2 TRPS1 ZNF705B ZNF705D ZNF551 ZNF705G

1.47e-068088015SM00355
DomainWxxW_domain

MUC5B MUC2 MUC5AC

1.50e-066803IPR025155
DomainMucin2_WxxW

MUC5B MUC2 MUC5AC

1.50e-066803PF13330
DomainEGF_CA

FBLN2 EFEMP1 JAG1 LRP1 LRP1B LRP8

1.83e-0686806PF07645
DomainCT

MUC5B MUC2 MUC5AC OTOG

2.15e-0622804SM00041
DomainCys_knot_C

MUC5B MUC2 MUC5AC OTOG

3.69e-0625804IPR006207
DomainCTCK_2

MUC5B MUC2 MUC5AC OTOG

3.69e-0625804PS01225
DomainEGF_Ca-bd_CS

FBLN2 EFEMP1 JAG1 LRP1 LRP1B LRP8

3.70e-0697806IPR018097
DomainEGF_CA

FBLN2 EFEMP1 JAG1 LRP1 LRP1B LRP8

4.17e-0699806PS01187
DomaincEGF

FBLN2 EFEMP1 LRP1 LRP1B

4.34e-0626804IPR026823
DomaincEGF

FBLN2 EFEMP1 LRP1 LRP1B

4.34e-0626804PF12662
DomainASX_HYDROXYL

FBLN2 EFEMP1 JAG1 LRP1 LRP1B LRP8

4.42e-06100806PS00010
Domain-

ZNF711 ZNF705A CTCFL ZNF142 BCL11B HIVEP1 ZNF560 ZNF157 ZNF296 ZNF705B ZNF705D ZNF551 ZNF705G

5.78e-0667980133.30.160.60
DomainEGF-type_Asp/Asn_hydroxyl_site

FBLN2 EFEMP1 JAG1 LRP1 LRP1B LRP8

6.19e-06106806IPR000152
Domainzf-C2H2

ZNF711 ZNF705A CTCFL ZNF142 BCL11B HIVEP1 ZNF560 ZNF157 ZNF296 TRPS1 ZNF705B ZNF705D ZNF551

7.20e-066938013PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF711 ZNF705A CTCFL ZNF142 BCL11B HIVEP1 ZNF560 ZNF157 ZNF296 ZNF705B ZNF705D ZNF551 ZNF705G

7.31e-066948013IPR013087
DomainEGF_LAM_2

HSPG2 MEGF9 LAMB1 LAMC1

7.86e-0630804PS50027
DomainEGF_LAM_1

HSPG2 MEGF9 LAMB1 LAMC1

7.86e-0630804PS01248
DomainLaminin_EGF

HSPG2 MEGF9 LAMB1 LAMC1

1.48e-0535804PF00053
DomainEGF_Lam

HSPG2 MEGF9 LAMB1 LAMC1

1.48e-0535804SM00180
DomainVWFC_1

CRIM1 MUC5B MUC2 MUC5AC

1.66e-0536804PS01208
DomainEGF

HSPG2 JAG1 LRP1 LRP1B TMEFF2 LRP8

1.67e-05126806PF00008
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

1.81e-052802IPR014744
DomainHAT_KAT11

CREBBP EP300

1.81e-052802PF08214
DomainKIX

CREBBP EP300

1.81e-052802PS50952
DomainZnF_TAZ

CREBBP EP300

1.81e-052802SM00551
DomainCBP_P300_HAT

CREBBP EP300

1.81e-052802IPR031162
DomainDUF5050

LRP1 LRP1B

1.81e-052802IPR032485
DomainDUF902

CREBBP EP300

1.81e-052802PF06001
Domain-

CREBBP EP300

1.81e-0528021.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

1.81e-052802IPR010303
Domain-

CREBBP EP300

1.81e-0528021.10.1630.10
DomainCreb_binding

CREBBP EP300

1.81e-052802PF09030
Domain-

CREBBP EP300

1.81e-0528021.10.246.20
Domainzf-TAZ

CREBBP EP300

1.81e-052802PF02135
DomainZF_TAZ

CREBBP EP300

1.81e-052802PS50134
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

1.81e-052802IPR013178
DomainDUF5050

LRP1 LRP1B

1.81e-052802PF16472
DomainKAT11

CREBBP EP300

1.81e-052802SM01250
DomainZnf_TAZ

CREBBP EP300

1.81e-052802IPR000197
DomainKIX_dom

CREBBP EP300

1.81e-052802IPR003101
DomainKIX

CREBBP EP300

1.81e-052802PF02172
DomainCBP_P300_HAT

CREBBP EP300

1.81e-052802PS51727
DomainVWFC_2

CRIM1 MUC5B MUC2 MUC5AC

2.06e-0538804PS50184
DomainLaminin_EGF

HSPG2 MEGF9 LAMB1 LAMC1

2.06e-0538804IPR002049
DomainLDLR_class-A_CS

HSPG2 LRP1 LRP1B LRP8

2.54e-0540804IPR023415
DomainLdl_recept_b

LRP1 LRP1B LRP8

2.66e-0514803PF00058
DomainLDLRB

LRP1 LRP1B LRP8

2.66e-0514803PS51120
DomainLY

LRP1 LRP1B LRP8

3.32e-0515803SM00135
DomainLDLR_classB_rpt

LRP1 LRP1B LRP8

3.32e-0515803IPR000033
DomainLdl_recept_a

HSPG2 LRP1 LRP1B LRP8

4.07e-0545804PF00057
Domain-

HSPG2 LRP1 LRP1B LRP8

4.44e-05468044.10.400.10
DomainLDLRA_1

HSPG2 LRP1 LRP1B LRP8

5.26e-0548804PS01209
DomainLDLRA_2

HSPG2 LRP1 LRP1B LRP8

5.71e-0549804PS50068
DomainLDrepeatLR_classA_rpt

HSPG2 LRP1 LRP1B LRP8

5.71e-0549804IPR002172
DomainLDLa

HSPG2 LRP1 LRP1B LRP8

5.71e-0549804SM00192
DomainCTCK_1

MUC5B MUC2 MUC5AC

5.90e-0518803PS01185
Domainzf-MYND

SMYD4 TDRD1 SMYD3

9.52e-0521803PF01753
DomainZnf_MYND

SMYD4 TDRD1 SMYD3

1.10e-0422803IPR002893
DomainZF_MYND_1

SMYD4 TDRD1 SMYD3

1.10e-0422803PS01360
DomainZF_MYND_2

SMYD4 TDRD1 SMYD3

1.10e-0422803PS50865
DomainACR

ADAMTS19 ADAM21 ADAM29

2.06e-0427803SM00608
DomainADAM_Cys-rich

ADAMTS19 ADAM21 ADAM29

2.06e-0427803IPR006586
DomainLIM

TRIP6 PRICKLE2 FHL2 FHL5

2.18e-0469804PF00412
DomainVWC

CRIM1 MUC5B MUC5AC

2.29e-0428803PF00093
Domain-

TRIP6 PRICKLE2 FHL2 FHL5

2.31e-04708042.10.110.10
DomainZnf_LIM

TRIP6 PRICKLE2 FHL2 FHL5

2.44e-0471804IPR001781
DomainLIM_DOMAIN_1

TRIP6 PRICKLE2 FHL2 FHL5

2.44e-0471804PS00478
DomainLIM_DOMAIN_2

TRIP6 PRICKLE2 FHL2 FHL5

2.44e-0471804PS50023
DomainLIM

TRIP6 PRICKLE2 FHL2 FHL5

2.44e-0471804SM00132
DomainNuc_rcpt_coact

CREBBP EP300

2.69e-046802IPR009110
DomainHirudin/antistatin

CRIM1 MUC5AC

3.75e-047802IPR011061
DomainLAMININ_IVA

HSPG2 LAMC1

4.99e-048802PS51115
DomainLaminin_B

HSPG2 LAMC1

4.99e-048802PF00052
DomainLamB

HSPG2 LAMC1

4.99e-048802SM00281
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

JAG1 CREBBP EP300

3.76e-0514683M27808
PathwayWP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX

CREBBP EP300 DNMT3A

1.34e-0421683M39593
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC5B MUC2 MUC5AC

1.34e-0421683MM15706
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

2.27e-045682MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

2.27e-045682M48020
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

2.27e-045682M48023
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

2.27e-045682M27228
PathwayPID_HDAC_CLASSIII_PATHWAY

FHL2 CREBBP EP300

2.58e-0426683M32
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

3.40e-046682M22062
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

COL24A1 LAMB1 LAMC1

3.97e-0430683M27772
PathwayREACTOME_LAMININ_INTERACTIONS

HSPG2 LAMB1 LAMC1

3.97e-0430683M27216
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

4.74e-047682MM1573
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

HSPG2 COL24A1 FBLN2 EFEMP1 LAMB1 LAMC1 ITGB2

5.89e-04300687M610
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

6.30e-048682M22058
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

6.30e-048682M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

6.30e-048682M48024
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

6.30e-048682M46443
PathwayKEGG_SMALL_CELL_LUNG_CANCER

TRAF5 LAMB1 BIRC2 LAMC1

7.15e-0484684M3228
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

8.08e-049682M47451
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

COL24A1 LAMB1 LAMC1

1.00e-0341683M27778
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

CREBBP EP300

1.01e-0310682M27945
PathwayWP_COMPLEMENT_SYSTEM

CD59 LAMB1 LAMC1 ITGB2

1.18e-0396684M39581
PathwayWP_SMALL_CELL_LUNG_CANCER

TRAF5 LAMB1 BIRC2 LAMC1

1.18e-0396684M39834
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

1.23e-0311682MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

1.23e-0311682M48021
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

CREBBP EP300

1.23e-0311682M26924
PathwayPID_INTEGRIN4_PATHWAY

LAMB1 LAMC1

1.23e-0311682M158
PathwayREACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS

UHRF2 CREBBP EP300

1.23e-0344683M27295
PathwayBIOCARTA_PRION_PATHWAY

LAMB1 LAMC1

1.47e-0312682M22020
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

1.47e-0312682M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

1.47e-0312682M27765
PathwayKEGG_MEDICUS_PATHOGEN_HSV_GD_TO_HVEM_NFKB_SIGNALING_PATHWAY

TRAF5 BIRC2

1.47e-0312682M47600
PathwayREACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS

NOD1 P2RX7 BIRC2

1.50e-0347683MM14664
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

JAG1 CREBBP EP300

1.50e-0347683M7946
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

HSPG2 LRP1 LRP8

1.59e-0348683M27642
PathwayREACTOME_SIGNALING_BY_NOTCH3

JAG1 CREBBP EP300

1.69e-0349683M618
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS19 MUC5B MUC2 MUC5AC

1.88e-03109684MM15164
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

2.31e-0315682MM1339
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

2.31e-0315682M10183
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

2.31e-0315682MM1439
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

CREBBP EP300

2.31e-0315682M953
PathwayREACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS

NOD1 P2RX7 BIRC2

2.48e-0356683M1074
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

CREBBP EP300

2.63e-0316682M27121
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC5B MUC5AC

2.63e-0316682M27410
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

2.63e-0316682M1296
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

2.63e-0316682MM1420
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

2.63e-0316682M8516
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES

CREBBP EP300

2.63e-0316682M27940
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

JAG1 CREBBP EP300

2.74e-0358683M29616
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

HSPG2 LAMB1 LAMC1

2.88e-0359683M27218
PathwayWP_CANCER_PATHWAYS

TRAF5 JAG1 LAMB1 BIRC2 LAMC1 F2R CREBBP EP300

2.94e-03507688M48302
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

2.98e-0317682MM1509
PathwayREACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA

CREBBP EP300

2.98e-0317682M48025
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC5B MUC5AC

2.98e-0317682M27412
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC5B MUC2 MUC5AC

3.02e-0360683MM15636
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC5B MUC2 MUC5AC

1.36e-08384319718741
Pubmed

Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.

HSPG2 FBLN2 LAMB1 LAMC1

2.23e-081384412682087
Pubmed

Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.

MUC5B MUC2 MUC5AC

5.43e-08484325638393
Pubmed

Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.

MUC5B MUC2 MUC5AC

5.43e-08484322269464
Pubmed

NF-κB and enhancer-binding CREB protein scaffolded by CREB-binding protein (CBP)/p300 proteins regulate CD59 protein expression to protect cells from complement attack.

CD59 CREBBP EP300

5.43e-08484324338025
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC5B MUC2 MUC5AC

5.43e-08484323807779
Pubmed

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

MUC5B MUC2 MUC5AC

5.43e-08484317471237
Pubmed

The mouse secreted gel-forming mucin gene cluster.

MUC5B MUC2 MUC5AC

5.43e-08484314984930
Pubmed

Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.

MUC5B MUC2 MUC5AC

5.43e-08484329869461
Pubmed

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

MUC5B MUC2 MUC5AC

5.43e-08484312676567
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

HSPG2 COL24A1 FBLN2 EFEMP1 LAMB1 LAMC1 MUC2

9.47e-0815384725037231
Pubmed

Polymorphism of human mucin genes in chest disease: possible significance of MUC2.

MUC5B MUC2 MUC5AC

1.35e-07584311062147
Pubmed

Differential expression of MUC genes in endometrial and cervical tissues and tumors.

MUC5B MUC2 MUC5AC

1.35e-07584316188033
Pubmed

Interaction and functional cooperation between the LIM protein FHL2, CBP/p300, and beta-catenin.

FHL2 CREBBP EP300

1.35e-07584315572674
Pubmed

Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens.

HSPG2 FBLN2 LAMC1

1.35e-07584312243745
Pubmed

Extracellular matrix protein fibulin-2 is expressed in the embryonic endocardial cushion tissue and is a prominent component of valves in adult heart.

FBLN2 LAMB1 LAMC1

1.35e-0758437851641
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

HSPG2 COL24A1 FBLN2 EFEMP1 LAMB1 LAMC1 MUC2

1.72e-0716784722159717
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC5B MUC2 MUC5AC

2.70e-07684319110483
Pubmed

Four-and-a-half LIM domain proteins inhibit transactivation by hypoxia-inducible factor 1.

FHL2 CREBBP EP300

2.70e-07684322219185
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

EFEMP1 CRIM1 MEGF9 MYCBP2 TRPS1 TRIM8 LRP1 LAMB1 BIRC2 USP16 LRP1B CREBBP EP300 SMYD3 ARMC8

4.08e-071285841535914814
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

HSPG2 HIVEP1 EFEMP1 CRIM1 LRP1 LAMB1

4.40e-0711884621078624
Pubmed

Signalling codes for the maintenance and lineage commitment of embryonic gastric epithelial progenitors.

JAG1 LGR5 EPCAM MUC5AC

5.33e-072784432878924
Pubmed

Specific ablation of the nidogen-binding site in the laminin gamma1 chain interferes with kidney and lung development.

HSPG2 LAMB1 LAMC1

7.54e-07884312015298
Pubmed

The effects of trichostatin A on mRNA expression of chromatin structure-, DNA methylation-, and development-related genes in cloned mouse blastocysts.

CREBBP EP300 DNMT3A

1.13e-06984318241125
Pubmed

Generation of a conditionally null allele of the laminin alpha1 gene.

HSPG2 LAMB1 LAMC1

1.61e-061084316100707
Pubmed

Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryo.

HSPG2 LAMB1 LAMC1

1.61e-061084316554364
Pubmed

Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage.

LGR5 MUC2 EPCAM

2.21e-061184334348153
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

JAG1 MUC5B MUC2 MUC5AC

2.99e-064184422675208
Pubmed

The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.

LAMB1 LAMC1 LGR5

3.82e-061384336350252
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

HSPG2 COL24A1 FBLN2 EFEMP1 LAMB1 LAMC1

4.37e-0617584628071719
Pubmed

Complement factor H, a marker of self protects against experimental autoimmune encephalomyelitis.

LRP1 CD59 ITGB2

4.85e-061484319299737
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

5.76e-06284227881875
Pubmed

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

MUC5B MUC5AC

5.76e-0628427513696
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

5.76e-06284234845315
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1 LRP1B

5.76e-06284215963947
Pubmed

The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.

MUC5B MUC5AC

5.76e-06284237146737
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

5.76e-06284219729597
Pubmed

MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.

MUC5B MUC5AC

5.76e-06284214988081
Pubmed

cDNA cloning, expression and mapping of human laminin B2 gene to chromosome 1q31.

LAMB1 LAMC1

5.76e-0628423402995
Pubmed

Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.

MUC5B MUC5AC

5.76e-06284215563276
Pubmed

The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.

MUC5B MUC5AC

5.76e-06284217621824
Pubmed

Muc5b is required for airway defence.

MUC5B MUC5AC

5.76e-06284224317696
Pubmed

Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.

MUC5B MUC5AC

5.76e-06284222391959
Pubmed

Differential glycosylation regulates processing of lipoprotein receptors by gamma-secretase.

LRP1 LRP8

5.76e-06284212871934
Pubmed

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.

MUC5B MUC5AC

5.76e-06284235776514
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

5.76e-06284239287984
Pubmed

The ocular surface phenotype of Muc5ac and Muc5b null mice.

MUC5B MUC5AC

5.76e-06284224327612
Pubmed

A novel disulfide pattern in laminin-type epidermal growth factor-like (LE) modules of laminin β1 and γ1 chains.

LAMB1 LAMC1

5.76e-06284220731416
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

5.76e-06284220717166
Pubmed

Specific glycoforms of MUC5AC and endorepellin accurately distinguish mucinous from nonmucinous pancreatic cysts.

HSPG2 MUC5AC

5.76e-06284223836919
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

5.76e-06284225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

5.76e-06284211559821
Pubmed

Gel-forming mucins form distinct morphologic structures in airways.

MUC5B MUC5AC

5.76e-06284228607090
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

5.76e-06284232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

5.76e-06284219822209
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

5.76e-06284224522976
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

5.76e-06284221847097
Pubmed

Mucolytic activity of bacterial and human chitinases.

MUC2 MUC5AC

5.76e-06284217321686
Pubmed

Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.

MUC5B MUC5AC

5.76e-06284231030254
Pubmed

Altered expression of MUC2 and MUC5AC in progression of colorectal carcinoma.

MUC2 MUC5AC

5.76e-06284220731025
Pubmed

The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.

MUC5B MUC5AC

5.76e-06284223527003
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

5.76e-06284234813504
Pubmed

Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.

MUC5B MUC5AC

5.76e-06284216540890
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

5.76e-06284220301699
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

5.76e-06284224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

5.76e-06284237816914
Pubmed

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

MUC5B MUC5AC

5.76e-06284227845589
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

5.76e-06284211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

5.76e-06284210918613
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

5.76e-06284235502657
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

5.76e-06284231898871
Pubmed

Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.

MUC5B MUC5AC

5.76e-06284227435107
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

5.76e-06284230888860
Pubmed

Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.

MUC5B MUC5AC

5.76e-06284226871672
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

5.76e-06284227881443
Pubmed

Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins.

MUC2 MUC5AC

5.76e-06284223832517
Pubmed

Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific distribution.

MUC2 MUC5AC

5.76e-06284223832516
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

5.76e-06284219272189
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

5.76e-06284232690000
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

5.76e-06284230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

5.76e-06284221803292
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

5.76e-0628429811832
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

5.76e-06284224089570
Pubmed

In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.

MUC5B MUC5AC

5.76e-06284211587997
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

5.76e-06284215706485
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

5.76e-06284239266679
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

5.76e-06284222303793
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

5.76e-06284234732714
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

5.76e-06284234019788
Pubmed

USP12 translocation maintains interferon antiviral efficacy by inhibiting CBP acetyltransferase activity.

USP12 CREBBP

5.76e-06284231899788
Pubmed

Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.

MUC5B MUC5AC

5.76e-06284234656442
Pubmed

Intestinal MUC2 and gastric M1/MUC5AC in preneoplastic lesions induced by 1,2-dimethylhydrazine in rat: a sequential analysis.

MUC2 MUC5AC

5.76e-06284217203232
Pubmed

Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.

MUC5B MUC5AC

5.76e-06284234058148
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

5.76e-06284215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

5.76e-06284229460469
Pubmed

Computational modeling of laminin N-terminal domains using sparse distance constraints from disulfide bonds and chemical cross-linking.

LAMB1 LAMC1

5.76e-06284220939100
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

5.76e-06284224551300
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

5.76e-06284233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

5.76e-0628429018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

5.76e-06284224648406
InteractionCACNA1A interactions

HSPG2 HIVEP1 EFEMP1 CRIM1 LRP1 LAMB1

8.83e-06123796int:CACNA1A
InteractionDYRK1A interactions

EFEMP1 CRIM1 MEGF9 MYCBP2 SPRING1 TBC1D2 LAMB1 FHL2 LRP1B CREBBP EP300

9.88e-065527911int:DYRK1A
InteractionGAA interactions

CPEB2 HSPG2 HIVEP1 CREBBP GNS EP300

1.50e-05135796int:GAA
InteractionCCN2 interactions

HSPG2 LRP1 CREBBP EP300

1.80e-0540794int:CCN2
InteractionZNF408 interactions

HSPG2 FBLN2 EFEMP1 FHL2 LRP1B FHL5

2.26e-05145796int:ZNF408
InteractionRBBP7 interactions

BCL11B HIVEP1 ZNF296 MYCBP2 CDIN1 TBC1D2 CREBBP GNS EP300 ZMYM3

2.83e-055077910int:RBBP7
InteractionGGH interactions

TRIP6 MYCBP2 ADAM21 LAMB1 LAMC1 TOR1B ZMYM3

4.71e-05243797int:GGH
InteractionNFATC1 interactions

BCL11B TRPS1 CREBBP EP300 ZMYM3 ARMC8

5.16e-05168796int:NFATC1
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF711 ZNF705A CTCFL ZNF142 BCL11B HIVEP1 ZNF560 ZNF157 ZNF296 TRPS1 ZNF705B ZNF705D ZNF551 ZNF705G

3.60e-07718681428
GeneFamilyLow density lipoprotein receptors

LRP1 LRP1B LRP8

1.42e-0513683634
GeneFamilyCD molecules|Mucins

MUC5B MUC2 MUC5AC

6.45e-0521683648
GeneFamilyLIM domain containing

TRIP6 PRICKLE2 FHL2 FHL5

7.13e-05596841218
GeneFamilyFibulins

FBLN2 EFEMP1

3.85e-048682556
GeneFamilyLaminin subunits

LAMB1 LAMC1

8.98e-0412682626
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.83e-0317682486
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

2.05e-031868291
GeneFamilyZinc fingers MYND-type

SMYD4 SMYD3

2.79e-032168287
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ADAM21 ADAM29

4.60e-032768247
GeneFamilyWD repeat domain containing|Caspase recruitment domain containing|Apoptosome

NOD1 BIRC2

5.66e-0330682959
GeneFamilyComplement system|Sushi domain containing

CD59 ITGB2

8.09e-0336682492
GeneFamilyTudor domain containing

UHRF2 TDRD1

8.53e-0337682780
GeneFamilyADAM metallopeptidase domain containing|CD molecules

JAG1 LRP1 CD59 EPCAM ITGB2

1.63e-02394685471
GeneFamilyUbiquitin specific peptidases

USP12 USP16

1.88e-0256682366
GeneFamilyRing finger proteins

TRAF5 TRIM8 BIRC2 UHRF2

1.99e-0227568458
CoexpressionNABA_MATRISOME

ADAMTS19 HSPG2 COL24A1 FBLN2 EFEMP1 CRIM1 MEGF9 OTOGL ADAM21 LAMB1 LAMC1 ADAM29 MUC5B MUC2 MUC5AC OTOG

6.53e-0810088116MM17056
CoexpressionNABA_CORE_MATRISOME

HSPG2 COL24A1 FBLN2 EFEMP1 CRIM1 OTOGL LAMB1 LAMC1 OTOG

1.56e-07270819MM17057
CoexpressionNABA_MATRISOME

ADAMTS19 HSPG2 COL24A1 FBLN2 EFEMP1 CRIM1 MEGF9 ADAM21 LAMB1 LAMC1 ADAM29 MUC5B MUC2 MUC5AC OTOG

5.08e-0710268115M5889
CoexpressionNABA_ECM_GLYCOPROTEINS

FBLN2 EFEMP1 CRIM1 OTOGL LAMB1 LAMC1 OTOG

2.16e-06191817MM17059
CoexpressionNABA_CORE_MATRISOME

HSPG2 COL24A1 FBLN2 EFEMP1 CRIM1 LAMB1 LAMC1 OTOG

2.20e-06275818M5884
CoexpressionCARRILLOREIXACH_HEPATOBLASTOMA_VS_NORMAL_HYPOMETHYLATED_AND_UP

HSPG2 TRPS1 LAMB1 LAMC1 LGR5 DNMT3A

1.12e-05162816M45037
CoexpressionJONES_OVARY_MAST_CELL

HSPG2 CRIM1 JAG1 CD59

1.36e-0547814M48356
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_ACTC_POS_SMC_CELL

ADAMTS19 HSPG2 TRAF5 CRIM1 JAG1 PRICKLE2 USP12 SLC2A13 FHL2 SMYD3

1.36e-055898110M45662
CoexpressionVERRECCHIA_EARLY_RESPONSE_TO_TGFB1

HSPG2 LRP1 CD59 ITGB2

2.38e-0554814M4737
CoexpressionP53_DN.V1_UP

FBLN2 EFEMP1 CRIM1 BIRC2 FHL2 EPCAM

3.11e-05194816M2698
CoexpressionNABA_ECM_GLYCOPROTEINS

FBLN2 EFEMP1 CRIM1 LAMB1 LAMC1 OTOG

3.30e-05196816M3008
CoexpressionGSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_DN

SMYD4 EFEMP1 TRIP6 CDIN1 EPCAM ARMC8

3.69e-05200816M6201
CoexpressionRIGGI_EWING_SARCOMA_PROGENITOR_UP

ZNF711 BCL11B P2RX7 JAG1 F2R ITGB2 TMEFF2 LRP8

6.22e-05437818M15981
CoexpressionHOSHIDA_LIVER_CANCER_SUBCLASS_S1

TRAF5 EFEMP1 MYCBP2 LAMB1 ITGB2 GNS

9.02e-05235816M5311
CoexpressionDESCARTES_FETAL_EYE_SMOOTH_MUSCLE_CELLS

CPEB2 COL24A1 P2RX7 SPRING1

9.65e-0577814M40182
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

CPEB2 MTMR6 BCL11B CRIM1 MEGF9 MYCBP2 PRICKLE2 ACVR1B LGR5 MUC2 LRP1B TMEFF2

1.44e-0411068112M39071
CoexpressionYAMAZAKI_TCEB3_TARGETS_UP

HSPG2 FBLN2 LAMB1 LAMC1 GNS

1.67e-04166815M1542
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_500

JAG1 TRPS1 LAMB1 LAMC1 LGR5 EPCAM

3.76e-05165806gudmap_kidney_P4_CapMesRenVes_Crym_k3_500
CoexpressionAtlasStromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2

HSPG2 EFEMP1 CRIM1 JAG1 LRP1 LAMB1 LAMC1 FHL2 FHL5

5.13e-05453809GSM777067_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000

COL24A1 BCL11B ZNF560 MEGF9 JAG1 TRPS1 SLC2A13 LRP8

8.72e-05377808gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k2
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_k-means-cluster#3_top-relative-expression-ranked_500

USP12 LAMB1 LAMC1 LGR5

9.40e-0563804gudmap_developingKidney_e14.5 whole kidney - wildtype_500_k3
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

FBLN2 EFEMP1 TRPS1 PRICKLE2 LRP1 LAMB1 LAMC1 F2R

3.55e-09195848f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

7.12e-08189847bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

7.38e-08190847bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

7.38e-08190847e275de94468872e70cf305b3b450823d4c9c5e3f
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

7.38e-08190847ee2f4a55d2fd18b83e55399b5b5697a15a2d2e70
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

7.38e-08190847f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

7.38e-08190847c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

ADAMTS19 FBLN2 TRPS1 PRICKLE2 LAMB1 LAMC1 SLC2A13

8.21e-08193847dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HSPG2 FBLN2 EFEMP1 PRICKLE2 LAMB1 LAMC1 LRP1B

9.44e-081978473bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HSPG2 FBLN2 EFEMP1 PRICKLE2 LAMB1 LAMC1 LRP1B

9.44e-0819784717344464fdcc5ba0c03959696b97c195f11e644c
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HSPG2 FBLN2 EFEMP1 PRICKLE2 LAMB1 LAMC1 LRP1B

9.44e-081978475b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS19 COL24A1 BCL11B TRPS1 TMEFF2 LRP8

1.18e-06180846e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM163B EFEMP1 LRP1 LAMB1 LAMC1 F2R

1.26e-06182846c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM163B EFEMP1 LRP1 LAMB1 LAMC1 F2R

1.26e-06182846dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBLN2 EFEMP1 PRICKLE2 LRP1 LAMC1 PFN2

1.39e-061858469faa35ceb89ccd2979072286f063687c9f846ce3
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

FBLN2 TRPS1 LRP1 LAMB1 LAMC1 F2R

1.52e-06188846fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCelldroplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBLN2 EFEMP1 LRP1 LAMC1 TMEFF2

1.62e-0619084647077579496c5340e99f61499427a3a36b566da3
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

1.67e-061918466cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCelldroplet-Fat-Gat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

1.67e-06191846850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCelldroplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBLN2 EFEMP1 LRP1 LAMC1 TMEFF2

1.67e-06191846a57cf0519d749febc0b69fe0b098b7ba53d63258
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

1.67e-061918468b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCelldroplet-Mammary_Gland-nan-18m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBLN2 EFEMP1 LRP1 LAMC1 TMEFF2

1.67e-0619184619c67a812b8ce97472d316acd15aeefe8736000d
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

COL24A1 FBLN2 TRPS1 LAMB1 LAMC1 SLC2A13

1.72e-06192846356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 FBLN2 EFEMP1 LRP1 LAMB1 LAMC1

1.72e-061928467b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBLN2 EFEMP1 LRP1 LAMB1 LAMC1

1.72e-061928462d9e2262f1342fe17735f21f733c029d1275e955
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

FBLN2 TRPS1 PRICKLE2 LAMB1 LAMC1 SLC2A13

1.83e-0619484611c79a8c56ece42713b04b321982e41e239f07a5
ToppCellfacs-MAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

1.83e-06194846f906b090f67df4cfe3498cdbb52cc0efa08e06cc
ToppCellfacs-MAT-Fat-18m-Mesenchymal|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

1.83e-06194846944cdb0403d80a10a2eea2a3516a9343dbccc32c
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

FBLN2 EFEMP1 TRPS1 LRP1 LAMB1 LAMC1

1.83e-06194846d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellfacs-GAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

1.83e-061948469709dc95fb6982b6a0467b507845d5bc17252e3e
ToppCellfacs-GAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

1.83e-0619484693b7a9065430740ec31fce4e8c14ffccb498591d
ToppCellfacs-GAT-Fat-18m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

1.83e-061948460d2e65b44e3f143971c2fd24c4552f042b049cfa
ToppCellfacs-MAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

1.83e-0619484685081d255fcc1e9854c0073321dd9f0feaa48866
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

COL24A1 FBLN2 TRPS1 LRP1 LAMC1 SLC2A13

1.88e-061958466a02ebbeb3199447ddce64d92d8809436e040eba
ToppCellfacs-SCAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

1.94e-0619684665f2f51e17f1869f3468813127b96d3048d8ad41
ToppCellfacs-SCAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

1.94e-06196846e4ed897900a6472738bc6be2fb4817192727225d
ToppCellfacs-SCAT-Fat-18m-Mesenchymal|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

1.94e-061968462cd83176f2e8a9e6fa3c08cb33928a61e5fc43b6
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 TMEFF2

1.94e-06196846ed6047b48b6a96baa6a90c7af784e7c34b32824d
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBLN2 EFEMP1 PRICKLE2 LRP1 LAMB1 LAMC1

2.00e-06197846ab5d3ebc73bd7cfc64381d14b92878b370205186
ToppCell5'-Adult-Appendix-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBLN2 EFEMP1 PRICKLE2 LRP1 LAMB1 LAMC1

2.00e-06197846b11a5d909942a4299cbc0b27332b1a3f66f3bccd
ToppCellfacs-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBLN2 EFEMP1 LRP1 LAMB1 LAMC1

2.06e-061988460dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 CRIM1 CD59 LAMB1 LAMC1 F2R

2.06e-061988467cddd474416651088a4e08edfc0ac420ff10a5fe
ToppCellILEUM-inflamed-(8)_Fibroblast|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FBLN2 EFEMP1 LRP1 LAMB1 LAMC1 FHL2

2.12e-06199846cb3c04b91c8e8080137823b11c76ca0a2adda52d
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EFEMP1 LRP1 LAMB1 LAMC1 FHL2 F2R

2.12e-061998466139687a3a5025cb98da4dba0183f95fcae3dc61
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EFEMP1 LRP1 LAMB1 LAMC1 FHL2 F2R

2.12e-06199846e78f661b40da34768469549b6e755d330be6bbd8
ToppCellmetastatic_Brain-Fibroblasts-FB-like_cells|Fibroblasts / Location, Cell class and cell subclass

HSPG2 FBLN2 EFEMP1 LRP1 LAMB1 FHL2

2.18e-06200846f62833c63f9c6a94b6cc2ba8e2f960e67f093f48
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FBLN2 LRP1 LAMB1 LAMC1 F2R LGR5

2.18e-06200846efdf7066b7dd43e35dbc0d2719b75f250cf54af2
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

FBLN2 EFEMP1 LRP1 LAMB1 F2R

4.61e-0612984513cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 BCL11B CRIM1 SPRING1 F2R

6.41e-0613884519ffd66256fa94d728138d37d0a5a3bac7722dbb
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 BCL11B CRIM1 SPRING1 F2R

6.41e-06138845321070b6900887b27da0f2b25808a05a8ab89ee7
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BCL11B PRICKLE2 LAMB1 SMYD3 ZMYM3

1.16e-051568458790b4b400695571fcf1ccb24c658b5e90854ff7
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF157 MUC5B TDRD1 EPCAM MUC5AC

1.66e-05168845b275e951ff7109e36da22fc17bd4516f9b9432c4
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF157 MUC5B TDRD1 EPCAM MUC5AC

1.66e-051688450757a5af953901a8faed5774ffec4755fc9c0a6e
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF157 MUC5B TDRD1 EPCAM MUC5AC

1.66e-05168845a0dbe2ee697e29b32aa5f8326445e067ff66c154
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

COL24A1 FBLN2 LAMB1 LAMC1 SLC2A13

1.71e-051698456373562ab3b1765060212a6a53d6543e7e942e80
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TESMIN TBC1D2 MUC5B LGR5 EPCAM

1.81e-05171845f2b31c97bbcc5164fc279ed0362007878887ad5e
ToppCell11.5-Airway-Epithelial-Basal_cell|Airway / Age, Tissue, Lineage and Cell class

EFEMP1 LGR5 MUC2 EPCAM MUC5AC

1.86e-051728459d4d92e2d16dfc8a394f2641653bb97de20a2530
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LINC01551 FBLN2 LRP1 LAMC1 TMEFF2

1.86e-05172845e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLA2G12B LGR5 MUC2 EPCAM MUC5AC

1.97e-05174845e7cca4b6a3935fad61cf2a3d9984ab1ffa1a9447
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLA2G12B LGR5 MUC2 EPCAM MUC5AC

1.97e-05174845ad5b56f0ace6455c033834b931ec870cc0dc9290
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 EFEMP1 DEFB119 LRP1 TMEFF2

1.97e-0517484568a6ed81e7e1f95b61f7ee20403980fa3a8db4d0
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L5-6_FEZF2_ANKRD20A1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS19 COL24A1 BCL11B HIVEP1 LRP8

1.97e-0517484599eb5e1aee136c7039e23b68a43a0fa3d775859f
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

FBLN2 EFEMP1 LRP1 LAMB1 LRP1B

2.08e-051768452e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

FBLN2 EFEMP1 LRP1 LAMB1 LRP1B

2.08e-05176845f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS19 COL24A1 BCL11B TMEFF2 LRP8

2.14e-051778454c069f0d044a96118090b85ca592a21d6b5d9399
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Paneth|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BCL11B MUC5B LGR5 EPCAM MUC5AC

2.14e-051778452af09028014f4ec3b7d2a4c286f1ae5e84a9f590
ToppCellICU-NoSEP-Myeloid-cDC1|ICU-NoSEP / Disease, Lineage and Cell Type

ZNF711 TRIP6 CD59 TDRD1 EPCAM

2.14e-0517784533cd2c183ee8b597012efcbcae72131ac6beaf4e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS19 COL24A1 BCL11B TMEFF2 LRP8

2.38e-0518184508f44323bf71b6004a921bbc969c954c75feeb66
ToppCellBasal|World / shred by cell class for mouse tongue

BCL11B EFEMP1 CRIM1 LAMB1 F2R

2.51e-05183845c6729a207526ff4aa48176207b9353176f631fea
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL24A1 OTOGL MUC5B LRP1B OTOG

2.57e-051848452cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL24A1 OTOGL MUC5B LRP1B OTOG

2.57e-05184845ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL24A1 OTOGL MUC5B LRP1B OTOG

2.57e-051848452b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-mature_NK_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCL11B P2RX7 FHL2 F2R ITGB2

2.57e-051848458095be57ed189763b5be039f330149a41e5b406a
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

FBLN2 LRP1 LAMB1 LAMC1 F2R

2.64e-051858458f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBLN2 EFEMP1 LRP1 LAMC1 LRP1B

2.71e-051868457582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS19 FBLN2 EFEMP1 LAMC1 TMEFF2

2.85e-05188845aa516273cdde53c8c0295f06830972388f890c97
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LRP1 LAMB1 LAMC1 TMEFF2

2.85e-051888457191087d8754f5e8700e3d744cd920ee26db1e57
ToppCellLV-14._Fibroblast_III|World / Chamber and Cluster_Paper

TRPS1 PRICKLE2 USP12 LAMB1 SLC2A13

2.93e-051898453922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCellfacs-BAT-Fat-18m-Mesenchymal|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LAMB1 LAMC1 TMEFF2

2.93e-05189845bba28f57a0708515fdd5acd9592dbbe4a4f57116
ToppCellfacs-BAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LAMB1 LAMC1 TMEFF2

2.93e-05189845cf293b23a4c0e8a0c9f09115b1d53d9b11de72e2
ToppCelldroplet-Lung-immune-endo-depleted|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 EFEMP1 LAMB1 LAMC1 F2R

2.93e-05189845c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCelldroplet-Lung-immune-endo-depleted-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 EFEMP1 LAMB1 LAMC1 F2R

2.93e-051898452a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Neuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

ZNF711 CPEB2 MTMR6 MYCBP2 LRP1

2.93e-051898453717d1148e26ac78a26aea0ca1dbfbb9d3668877
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMC1 TMEFF2

2.93e-051898450a8b827bba1efd885ad6c06929251c741dc3a541
ToppCellfacs-BAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LAMB1 LAMC1 TMEFF2

2.93e-0518984587323e86a5b5d159920a07e6bd7ef5e3438cd085
ToppCelldroplet-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 EFEMP1 LAMB1 LAMC1 F2R

2.93e-051898455a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 EFEMP1 LAMB1 LAMC1 F2R

3.00e-051908459cd147a174017ebda23cc47b6d4552d898acd092
ToppCellfacs-GAT-Fat-24m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 TMEFF2

3.00e-051908453720e64129f3f3268b1dc14031a76f41c38241c2
ToppCellfacs-GAT-Fat-24m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 TMEFF2

3.00e-0519084573a50426f972f08f9bb525ad5c0b774187ab5d6a
ToppCellfacs-GAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 TMEFF2

3.00e-05190845b55cf1fb586b724295b7b038483249847bb344fc
ToppCelldroplet-Mammary_Gland-nan-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBLN2 EFEMP1 LRP1 LAMC1

3.08e-051918458022059e434fd411dc539819f969bd4f94861281
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EFEMP1 LRP1 LAMB1 LAMC1 F2R

3.08e-0519184544a9a6768084dafc641ad455b65862bfd4cc0cb9
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EFEMP1 MEGF9 LAMB1 LAMC1 TMEFF2

3.16e-0519284530cefa0990ba1f379f350bfbf994a78db145075e
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBLN2 LRP1 LAMB1 LAMC1

3.16e-05192845671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCellfacs-BAT-Fat-24m-Mesenchymal-mesenchymal_progenitor|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 TMEFF2

3.16e-051928450b3161ce3add9f7457f4cfa5749dbb6501e3ad36
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBLN2 EFEMP1 LRP1 LAMB1 LAMC1

3.16e-05192845321850b0f881420c2d57d3e825e365c82fa511ab
ToppCellfacs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBLN2 LRP1 LAMB1 LAMC1

3.16e-05192845a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCellfacs-BAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 TMEFF2

3.16e-0519284561c7ec6171c519b2f3e9ce623669162c0c6ba9f5
ToppCellfacs-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBLN2 LRP1 LAMB1 LAMC1

3.16e-05192845eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCellfacs-BAT-Fat-24m-Mesenchymal|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 EFEMP1 LRP1 LAMB1 TMEFF2

3.16e-0519284524d682e3247a73d349e7776b9e564b6b57f4cb13
ComputationalGenes in the cancer module 3.

HSPG2 EFEMP1 CRIM1 TRIP6 LAMB1 BIRC2 FHL2 F2R

1.67e-04384458MODULE_3
Computationalcell line expressed genes.

SLC6A11 HSPG2 EFEMP1 CRIM1 LAMB1 LGR5 EPCAM ITGB2

2.56e-04409458MODULE_118
ComputationalTrachea genes.

HSPG2 FBLN2 CRIM1 LRP1 BIRC2 MUC5B EPCAM ZMYM3

2.83e-04415458MODULE_6
ComputationalCell line expressed genes.

HSPG2 EFEMP1 CRIM1 LAMB1 BIRC2 FHL2 LGR5 EPCAM

3.71e-04432458MODULE_52
ComputationalNeighborhood of PTX3

EFEMP1 LAMB1 LAMC1

4.44e-0436453GNF2_PTX3
ComputationalOvary genes.

HSPG2 CRIM1 TRIP6 LRP1 LAMB1 BIRC2 FHL2

7.68e-04368457MODULE_1
ComputationalDRG (dorsal root ganglia) genes.

HSPG2 FBLN2 CRIM1 MEGF9 LRP1 LAMB1 BIRC2

9.87e-04384457MODULE_2
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

TRIP6 TRPS1 TRIM8 USP16 CREBBP EP300 LRP8

2.30e-061708071050_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA

ZNF142 TRIP6 TRPS1 TRIM8 CREBBP EP300 LRP8

2.48e-061728071072_DN
DrugLorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; PC3; HT_HG-U133A

NOD1 P2RX7 MEGF9 JAG1 TDRD1 MUC2 MUC5AC

6.08e-061978074658_UP
DrugAC1O4QI2

JAG1 LRP1 CD59 F2R ITGB2 EP300

8.87e-06137806CID006398444
DrugGrgds

FBLN2 LAMB1 LAMC1 FHL2 ITGB2

1.11e-0583805CID000123811
DrugVerteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A

EFEMP1 CRIM1 MEGF9 LAMB1 LAMC1 GNS

2.22e-051618063556_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

ZNF142 HIVEP1 TRIP6 TRPS1 TRIM8 CREBBP

2.38e-051638067453_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

NOD1 TRIP6 TRPS1 TRIM8 CREBBP DNMT3A

2.92e-051698066064_DN
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA

HIVEP1 TRIP6 TRPS1 TRIM8 EP300 LRP8

3.12e-051718061000_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BCL11B HIVEP1 TRIP6 TRPS1 TRIM8 CREBBP

3.12e-051718064954_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

HIVEP1 TRIP6 TRPS1 TRIM8 CREBBP LRP8

3.22e-051728063428_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

TRIP6 TRPS1 TRIM8 ACVR1B USP16 LRP8

3.22e-051728065209_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

TRAF5 HIVEP1 TRIP6 TRPS1 TRIM8 CREBBP

3.22e-051728066993_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

TRIP6 TRPS1 USP16 CREBBP EP300 LRP8

3.33e-051738062881_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

TRAF5 HIVEP1 TRIP6 TRPS1 TRIM8 CREBBP

3.44e-051748063462_DN
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA

TRIP6 TRPS1 TRIM8 CREBBP EP300 LRP8

3.55e-051758061058_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

TRAF5 HIVEP1 TRIP6 TRIM8 CREBBP LRP8

3.55e-051758067236_DN
DrugSAHA; Down 200; 10uM; MCF7; HT_HG-U133A

ZNF142 TRPS1 TRIM8 CREBBP EP300 LRP8

3.78e-051778061645_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

TRAF5 TRIP6 TRPS1 TRIM8 CREBBP LRP8

3.91e-05178806992_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

HIVEP1 TRIP6 TRPS1 TRIM8 USP16 LRP8

3.91e-051788066276_DN
DrugAC1L1C2F

HSPG2 COL24A1 LAMB1 LAMC1 MUC5AC

4.33e-05110805CID000001711
DrugAC1L9IGO

HIVEP1 JAG1 CD59 ACVR1B ITGB2 EP300

4.70e-05184806CID000445722
Drug3-(4-methylphenylsulfonyl)-2-propenenitrile

EFEMP1 BIRC2 MUC5AC CREBBP EP300

4.92e-05113805ctd:C434003
DrugMebendazole [31431-39-7]; Down 200; 13.6uM; MCF7; HT_HG-U133A

BCL11B MEGF9 JAG1 GNS DNMT3A ARMC8

6.86e-051978062300_DN
DiseaseColorectal Carcinoma

MLH3 FBLN2 BCL11B EFEMP1 ZNF560 P2RX7 LRP1 LAMC1 ADAM29 UHRF2 LGR5 EP300

3.58e-077027912C0009402
DiseaseMenke-Hennekam syndrome

CREBBP EP300

7.08e-062792cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

7.08e-062792DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

7.08e-062792cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

7.08e-062792C4551859
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

7.08e-062792180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

7.08e-062792cv:C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

7.08e-062792DOID:1933 (is_implicated_in)
Diseasecystitis (is_marker_for)

MUC2 MUC5AC

7.08e-062792DOID:1679 (is_marker_for)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

7.08e-062792C0035934
Diseasesputum mucin-5B amount

MUC2 MUC5AC

2.12e-053792OBA_2050332
Diseaseactivities of daily living score measurement

TRPS1 SLC2A13 FHL2

2.37e-0521793EFO_0008451
Diseasepulse pressure measurement, migraine with aura

LRP1 FHL5

4.23e-054792EFO_0005763, MONDO_0005475
Diseasemucinous adenocarcinoma (is_marker_for)

MUC2 MUC5AC

7.04e-055792DOID:3030 (is_marker_for)
Diseasemigraine without aura

LRP1 FHL5

7.04e-055792MONDO_0100431
Diseasehepatocellular carcinoma (is_marker_for)

EFEMP1 JAG1 PFN2 EPCAM LRP1B DNMT3A

1.60e-04301796DOID:684 (is_marker_for)
DiseaseAbdominal Migraine

LRP1 FHL5

2.52e-049792C0270858
DiseaseSick Headaches

LRP1 FHL5

2.52e-049792C0700438
DiseaseAcute Confusional Migraine

LRP1 FHL5

2.52e-049792C0521664
DiseaseLynch Syndrome

MLH3 EPCAM

2.52e-049792C4552100
DiseaseStatus Migrainosus

LRP1 FHL5

2.52e-049792C0338489
Diseasepulse pressure measurement, migraine without aura, susceptibility to, 4

LRP1 FHL5

2.52e-049792EFO_0005763, MONDO_0011847
DiseaseCervical Migraine Syndrome

LRP1 FHL5

2.52e-049792C0007852
DiseaseHemicrania migraine

LRP1 FHL5

2.52e-049792C0018984
Diseasebringing up phlegm, sputum or mucus on most days, self-reported

MUC2 MUC5AC

2.52e-049792EFO_0009824
Diseaseadult onset asthma

LRP1 UHRF2 MUC2 MUC5AC

2.90e-04118794EFO_1002011
Diseasesleep quality

TRPS1 SLC2A13 LRP1B OTOG

2.90e-04118794EFO_0005272
DiseaseFacies

JAG1 DNMT3A

3.14e-0410792C0282631
Diseasepneumonia (implicated_via_orthology)

MUC2 ITGB2

3.14e-0410792DOID:552 (implicated_via_orthology)
Diseaseallergic rhinitis (biomarker_via_orthology)

ITGB2 MUC5AC

3.14e-0410792DOID:4481 (biomarker_via_orthology)
Diseasebody surface area

COL24A1 FBLN2 BCL11B HIVEP1 EFEMP1 CRIM1 TRPS1 DNMT3A

3.26e-04643798EFO_0022196
Diseasepulmonary fibrosis

MUC5B MUC5AC

3.83e-0411792EFO_0009448
DiseaseDiffuse Large B-Cell Lymphoma

TRAF5 CREBBP EP300

4.38e-0455793C0079744
DiseaseMigraine Disorders

LRP1 FHL5

5.42e-0413792C0149931
Diseasered blood cell density measurement

BCL11B HIVEP1 CDIN1 JAG1 TRPS1 LAMC1 ACVR1B UHRF2 DNMT3A

5.70e-04880799EFO_0007978
Diseasecystic fibrosis (is_marker_for)

MUC5B MUC2 MUC5AC

6.23e-0462793DOID:1485 (is_marker_for)
Diseasecholangiocarcinoma (is_marker_for)

MUC5B MUC2 MUC5AC

6.84e-0464793DOID:4947 (is_marker_for)
Diseasecortical thickness

HSPG2 BCL11B CRIM1 MEGF9 MYCBP2 JAG1 TRPS1 LRP1 LAMC1 LRP8

7.61e-0411137910EFO_0004840
Diseaseneuroticism measurement, cognitive function measurement

LINC01551 BCL11B HIVEP1 TRPS1 LRP1B TMEFF2 LRP8

8.10e-04566797EFO_0007660, EFO_0008354
Diseasemigraine without aura, susceptibility to, 4

LRP1 FHL5

8.29e-0416792MONDO_0011847
DiseaseCraniofacial Abnormalities

HSPG2 TRPS1 EP300 DNMT3A

8.30e-04156794C0376634
DiseaseColorectal Neoplasms

MLH3 FBLN2 EFEMP1 LGR5 EP300

9.00e-04277795C0009404
Diseaseschizophrenia, irritable bowel syndrome

EP300 LRP8

9.38e-0417792EFO_0000555, MONDO_0005090
Diseasecervical artery dissection

LRP1 FHL5

9.38e-0417792EFO_1000059
Diseasestomach cancer (is_implicated_in)

ACVR1B LRP1B DNMT3A

9.64e-0472793DOID:10534 (is_implicated_in)
Diseaseosteochondrodysplasia (is_implicated_in)

HSPG2 TRPS1

1.18e-0319792DOID:2256 (is_implicated_in)
DiseaseLeukemia, Myelocytic, Acute

FHL2 CREBBP EP300 DNMT3A

1.22e-03173794C0023467
DiseaseProstatic Neoplasms

TBC1D2 LAMC1 EPCAM LRP1B CREBBP ZMYM3 TMEFF2

1.32e-03616797C0033578
DiseaseMalignant neoplasm of prostate

TBC1D2 LAMC1 EPCAM LRP1B CREBBP ZMYM3 TMEFF2

1.32e-03616797C0376358
Diseaseinfluenza A (H1N1)

TRPS1 TBC1D2 LRP1B

1.67e-0387793EFO_1001488
Diseasetobacco smoke exposure measurement

FAM163B FHL2

1.88e-0324792EFO_0009115
Diseasediastolic blood pressure, systolic blood pressure

BCL11B EFEMP1 CRIM1 JAG1 TRPS1 LRP1 FHL2

2.13e-03670797EFO_0006335, EFO_0006336
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

MLH3 EPCAM

2.21e-0326792C0009405
Diseasemigraine disorder, pulse pressure measurement

LRP1 FHL5

2.21e-0326792EFO_0005763, MONDO_0005277
Diseaseupper face morphology measurement

BCL11B EFEMP1 ARMC8

2.27e-0397793EFO_0010949
DiseaseMalignant neoplasm of breast

ADAMTS19 EFEMP1 OTOGL JAG1 BIRC2 ZFYVE26 FHL2 EP300 DNMT3A

2.28e-031074799C0006142
DiseaseColorectal cancer

MLH3 EP300

2.38e-0327792cv:C0346629
DiseaseHereditary non-polyposis colorectal cancer syndrome

MLH3 EPCAM

2.38e-0327792C1112155
DiseaseCOLORECTAL CANCER

MLH3 EP300

2.38e-0327792114500
DiseaseNeoplasm of the large intestine

MLH3 EP300

2.38e-0327792cv:C0009404
DiseaseSezary Syndrome

CREBBP DNMT3A

2.38e-0327792C0036920
DiseaseAdenoid Cystic Carcinoma

JAG1 CREBBP EP300

2.48e-03100793C0010606
DiseasePancreatic Neoplasm

EFEMP1 EPCAM EP300

2.48e-03100793C0030297
DiseaseMalignant neoplasm of pancreas

EFEMP1 EPCAM EP300

2.62e-03102793C0346647

Protein segments in the cluster

PeptideGeneStartEntry
FGSLRCSQCKQTYYC

TDRD1

176

Q9BXT4
GYCYEKSCHDRNEQC

ADAM29

491

Q9UKF5
CEDYDLCITCYNTKN

EP300

1686

Q09472
ECVCENYKLAVNCFV

EPCAM

26

P16422
VCCCQSEIFKYEFSN

LINC01551

66

Q86U37
QCCQCSYASRDTYKL

CTCFL

371

Q8NI51
NCKNCFLECAYQYDD

DNMT3A

516

Q9Y6K1
CSDSAYCYQKRCNNH

ADAM21

496

Q9UKJ8
RNTHCCYTDYCNRID

ACVR1B

91

P36896
TVCEDYDLCINCYNT

CREBBP

1721

Q92793
ENELTYYCCKKDLCN

CD59

81

P13987
NYNVRVLCCDDYSHC

MUC5B

1871

Q9HC84
CHSYNECVALEYRCD

HSPG2

206

P98160
CCETCRDFYAQKLQQ

ADAMTS19

1191

Q8TE59
QCINTYGTYKCLCTD

LRP1B

2981

Q9NZR2
KIASSCQLCDGYCYN

LRP1B

4386

Q9NZR2
YYHQDKEAAICRCSQ

MTMR6

191

Q9Y217
DRCQYRQCSGYCENF

LRP1

4301

Q07954
RCSQECANIYGSYQC

FBLN2

951

P98095
YVINVQCQFCEYDVC

MLH3

306

Q9UHC1
YKRCKYDTCNCQNNE

MUC2

611

Q02817
CANYLKLTYCNACSA

NOD1

676

Q9Y239
CENGYYNFDSICRKC

MEGF9

386

Q9H1U4
YYGDALQQDCRKCVC

LAMB1

1016

P07942
VECTYKAEACVCTYN

MUC5AC

1266

P98088
CYNYEIRIQCCETVN

MUC5AC

1661

P98088
HCYYALCSQDCQVVR

MUC5AC

4806

P98088
DVCYDTCGANKYRCD

PLA2G12B

116

Q9BX93
KNEQPYLYCRNCQSC

DEFB119

41

Q8N690
SECQRYVYSILCCKE

F2R

376

P25116
CCQEAAIVGYCDAKY

PFN2

16

P35080
CFESLYAEYCDTCAQ

PRICKLE2

246

Q7Z3G6
GQYCECDTINCERYN

ITGB2

531

P05107
CKCCQPCVVNEYYYR

P2RX7

371

Q99572
RYTQEYICQIFSHCC

ARMC8

161

Q8IUR7
TCYDRVFSNYCEECK

FHL5

31

Q5TD97
ERPYKCELCNYACAQ

BCL11B

821

Q9C0K0
NVTCLQYYCEFCWAN

CPEB2

546

Q7Z5Q1
LANQVYQCIVNDCCY

CDIN1

136

Q9Y2V0
CYCRLQYYCCKKDES

FAM163B

26

P0C2L3
KPCQSSYCYCQEVLD

GPAT2

606

Q6NUI2
CFTAQCGEINCERYY

CRIM1

366

Q9NZV1
DCYSNEYSSKCQECK

FHL2

91

Q14192
DCVCEDAYNNTYACV

GNS

441

P15586
KCIYNTAGFYCDRCK

LAMC1

851

P11047
CRCHAYNGKCQAVYT

DPY19L2P2

341

Q6ZN68
CSQICVNYKGYFKCE

LRP8

386

Q14114
AYQCCAFGVCENAYK

LGR5

476

O75473
LCTSIAAYAYKCCQE

OTOGL

1176

Q3ZCN5
TCRDLVNDFYCDCKN

JAG1

681

P78504
NYNINTYARFCKCCR

OTOG

2876

Q6ZRI0
NCRRSGCLKNYCECY

TESMIN

371

Q9Y4I5
GQNATCTRYSYCNEC

SLC2A13

431

Q96QE2
DECRTSSYLCQYQCV

EFEMP1

296

Q12805
SAYEYCVSCCLQPNK

SPRING1

126

Q9H741
GCSYAKYCSQECLQQ

SMYD4

311

Q8IYR2
TVTCVCQFKCNNDYV

TMEFF2

86

Q9UIK5
GTDFLEYKCRYCCSV

MYCBP2

4591

O75592
KQLRDQYCFECDCFR

SMYD3

251

Q9H7B4
DNCCKREVLNLYVYC

TRAF5

96

O00463
YYVGRNDDVKCFCCD

BIRC2

296

Q13490
SADYCRYVKQQCRQA

COL24A1

231

Q17RW2
LCDECNVAYHIYCLN

UHRF2

361

Q96PU4
CKYSDSFCENYNEYC

RNASE13

86

Q5GAN3
CYKCRQCSFTAADTQ

TRPS1

691

Q9UHF7
AYCEGCYVATLEKCA

TRIP6

326

Q15654
YECNECGNAFYVKAR

ZNF157

386

P51786
SYQCNLCEKAYTNCF

ZNF705A

171

Q6ZN79
CYVCDNEVQYCSSNQ

USP16

116

Q9Y5T5
YQCCECGKSFRQIFN

ZNF551

391

Q7Z340
CSEYKYYCEECRSKQ

USP12

226

O75317
YNNNCYRDCIMLCCL

SLC6A11

326

P48066
SYQCNLCEKAYTNCF

ZNF705EP

171

A8MWA4
SYQCNLCEKAYTNCF

ZNF705G

171

A8MUZ8
SYQCNLCEKAYTNCF

ZNF705B

171

P0CI00
SYQCNLCEKAYTNCF

ZNF705D

171

P0CH99
YQCPECEYCTNRADA

ZNF142

1536

P52746
KPYQCQYCIFRCADQ

ZNF711

531

Q9Y462
CEAEQVAVCQYCCYY

TRIM8

156

Q9BZR9
ARVCDQCYSYCNKDV

ZFYVE26

1861

Q68DK2
YICEYCNRACAKPSV

HIVEP1

406

P15822
LKTNCCDQCGAYIYT

ZMYM3

446

Q14202
CAYLQARNCQVESKY

TBC1D2

496

Q9BYX2
YKCNACEKAYSRSCV

ZNF560

656

Q96MR9
YNDIYCRFAECCREE

TOR1B

46

O14657
YCNVCDCVVKDSINF

ZMAT2

81

Q96NC0
ERPYTCEFCNYACAQ

ZNF296

411

Q8WUU4