Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainNxph

NXPH1 NXPH3 NXPH2

1.20e-074593IPR010450
DomainNXPH/NXPE

NXPH1 NXPH3 NXPH2

1.66e-068593IPR026845
DomainNeurexophilin

NXPH1 NXPH3 NXPH2

1.66e-068593PF06312
DomainTransmembrane_161A/B

TMEM161A TMEM161B

9.81e-062592IPR019395
DomainTmemb_161AB

TMEM161A TMEM161B

9.81e-062592PF10268
DomainLRRC8_Pannexin-like

LRRC8E LRRC8A

9.75e-055592IPR021040
DomainPannexin_like

LRRC8E LRRC8A

9.75e-055592PF12534
DomainTyr_kinase_rcpt_3_CS

FLT4 KDR

2.71e-048592IPR001824
DomainRECEPTOR_TYR_KIN_III

FLT4 KDR

2.71e-048592PS00240
DomainIL-1_rcpt_fam

IL1RAPL1 IL1RAPL2

5.30e-0411592IPR015621
DomainSSD

SCAP PTCHD3

7.48e-0413592IPR000731
DomainSSD

SCAP PTCHD3

7.48e-0413592PS50156
DomainNA_NEUROTRAN_SYMP_2

SLC6A4 SLC6A20

1.45e-0318592PS00754
DomainSNF

SLC6A4 SLC6A20

1.62e-0319592PF00209
DomainNA_NEUROTRAN_SYMP_1

SLC6A4 SLC6A20

1.62e-0319592PS00610
DomainNA_NEUROTRAN_SYMP_3

SLC6A4 SLC6A20

1.62e-0319592PS50267
DomainNa/ntran_symport

SLC6A4 SLC6A20

1.62e-0319592IPR000175
DomainTIR

IL1RAPL1 IL1RAPL2

1.98e-0321592SM00255
DomainTIR

IL1RAPL1 IL1RAPL2

2.18e-0322592PF01582
Domain-

IL1RAPL1 IL1RAPL2

2.38e-03235923.40.50.10140
DomainTIR

IL1RAPL1 IL1RAPL2

2.59e-0324592PS50104
DomainTIR_dom

IL1RAPL1 IL1RAPL2

2.81e-0325592IPR000157
Domainig

IL1RAPL1 FLT4 IL1RAPL2 KDR

3.05e-03190594PF00047
DomainImmunoglobulin

IL1RAPL1 FLT4 IL1RAPL2 KDR

3.05e-03190594IPR013151
DomainZnF_U1

TUT7 ZNF407

3.77e-0329592SM00451
DomainZnf_U1

TUT7 ZNF407

3.77e-0329592IPR003604
Domain7tm_1

OR12D2 P2RY12 OR6J1 OPN5 GPR162 HCRTR1 OR5F1

5.30e-03677597PF00001
DomainG_PROTEIN_RECEP_F1_1

OR12D2 P2RY12 OR6J1 OPN5 GPR162 HCRTR1 OR5F1

5.64e-03685597PS00237
DomainG_PROTEIN_RECEP_F1_2

OR12D2 P2RY12 OR6J1 OPN5 GPR162 HCRTR1 OR5F1

5.91e-03691597PS50262
DomainGPCR_Rhodpsn

OR12D2 P2RY12 OR6J1 OPN5 GPR162 HCRTR1 OR5F1

5.96e-03692597IPR000276
Pubmed

Structure and evolution of neurexophilin.

NXPH1 NXPH3 NXPH2

5.65e-0856338699246
Pubmed

Neurexophilins form a conserved family of neuropeptide-like glycoproteins.

NXPH1 NXPH3 NXPH2

5.65e-0856339570794
Pubmed

Neurexophilin binding to alpha-neurexins. A single LNS domain functions as an independently folding ligand-binding unit.

NXPH1 NXPH3 NXPH2

1.97e-0776339856994
Pubmed

Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8.

PREB TMEM161A TMEM161B LMBRD2

5.51e-073663438070861
Pubmed

VEGF receptor subtypes may serve as novel prognostic factors and putative indicators for anti VEGF receptor treatment response in renal cell carcinoma cases.

FLT4 KDR

3.23e-06263227837630
Pubmed

The detection of tumor location and lymph node metastasis by aberrant NXPH1 and NXPH2 expressions in pancreatic ductal adenocarcinomas.

NXPH1 NXPH2

3.23e-06263227817196
Pubmed

Heterodimerization with vascular endothelial growth factor receptor-2 (VEGFR-2) is necessary for VEGFR-3 activity.

FLT4 KDR

3.23e-06263215474514
Pubmed

Neurexophilin 3 is highly localized in cortical and cerebellar regions and is functionally important for sensorimotor gating and motor coordination.

NXPH1 NXPH3

3.23e-06263216055736
Pubmed

Protocadherin-alpha family is required for serotonergic projections to appropriately innervate target brain areas.

SLC6A4 PCDHAC2

3.23e-06263219625505
Pubmed

VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts.

FLT4 KDR

3.23e-06263220224550
Pubmed

VEGFR signaling during lymphatic vascular development: From progenitor cells to functional vessels.

FLT4 KDR

3.23e-06263225399804
Pubmed

Altered sleep homeostasis after restraint stress in 5-HTT knock-out male mice: a role for hypocretins.

SLC6A4 HCRTR1

3.23e-06263220007481
Pubmed

[Expression of VEGFR-2 and VEGFR-3 in papillary renal cell carcinoma and their relationship with prognosis].

FLT4 KDR

3.23e-06263221163065
Pubmed

Combined blockade of VEGFR-2 and VEGFR-3 inhibits inflammatory lymphangiogenesis in early and middle stages.

FLT4 KDR

3.23e-06263221273538
Pubmed

LRRC8 family proteins within lysosomes regulate cellular osmoregulation and enhance cell survival to multiple physiological stresses.

LRRC8E LRRC8A

3.23e-06263233139539
Pubmed

Two novel members of the interleukin-1 receptor gene family, one deleted in Xp22.1-Xp21.3 mental retardation.

IL1RAPL1 IL1RAPL2

3.23e-06263210757639
Pubmed

Conserved signaling through vascular endothelial growth (VEGF) receptor family members in murine lymphatic endothelial cells.

FLT4 KDR

3.23e-06263221839079
Pubmed

Modulation of VEGFR-2-mediated endothelial-cell activity by VEGF-C/VEGFR-3.

FLT4 KDR

3.23e-06263212393458
Pubmed

Vascular endothelial growth factor receptors VEGFR-2 and VEGFR-3 are localized primarily to the vasculature in human primary solid cancers.

FLT4 KDR

3.23e-06263220606037
Pubmed

Viral vascular endothelial growth factors vary extensively in amino acid sequence, receptor-binding specificities, and the ability to induce vascular permeability yet are uniformly active mitogens.

FLT4 KDR

3.23e-06263212867434
Pubmed

Cooperative and redundant roles of VEGFR-2 and VEGFR-3 signaling in adult lymphangiogenesis.

FLT4 KDR

3.23e-06263217210781
Pubmed

Expansion of cortical and medullary sinuses restrains lymph node hypertrophy during prolonged inflammation.

FLT4 KDR

3.23e-06263222430738
Pubmed

Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting.

FLT4 KDR

3.23e-06263217535974
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

HIPK3 TMEM161A SGMS1 TMEM161B LRRC8A ZNF407 FBXO34 CCNC

5.56e-0653663815840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

HIPK3 TMEM161A SGMS1 TMEM161B LRRC8A ZNF407 FBXO34 CCNC

5.71e-0653863810512203
Pubmed

The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells.

FLT4 KDR

9.68e-06363216530705
Pubmed

Early endocardial morphogenesis requires Scl/Tal1.

FLT4 KDR

9.68e-06363217722983
Pubmed

Angiogenesis interactome and time course microarray data reveal the distinct activation patterns in endothelial cells.

FLT4 KDR

9.68e-06363225329517
Pubmed

Prognostic significance of epidermal growth factor receptor and vascular endothelial growth factor receptor in colorectal adenocarcinoma.

FLT4 KDR

9.68e-06363221635552
Pubmed

Expression and localization of VEGF receptors in human fetal skeletal tissues.

FLT4 KDR

9.68e-06363223059888
Pubmed

Heterogeneity in VEGFR3 levels drives lymphatic vessel hyperplasia through cell-autonomous and non-cell-autonomous mechanisms.

FLT4 KDR

9.68e-06363229615616
Pubmed

Generating Vegfr3 reporter transgenic mouse expressing membrane-tagged Venus for visualization of VEGFR3 expression in vascular and lymphatic endothelial cells.

FLT4 KDR

9.68e-06363230601868
Pubmed

Haploinsufficiency of vascular endothelial growth factor related signaling genes is associated with tetralogy of Fallot.

FLT4 KDR

9.68e-06363230232381
Pubmed

Interplay of vascular endothelial growth factor receptors in organ-specific vessel maintenance.

FLT4 KDR

9.68e-06363235050301
Pubmed

Tubular network formation by adriamycin-resistant MCF-7 breast cancer cells is closely linked to MMP-9 and VEGFR-2/VEGFR-3 over-expressions.

FLT4 KDR

9.68e-06363222542663
Pubmed

Explorative investigation of vascular endothelial growth factor receptor expression in primary ovarian cancer and its clinical relevance.

FLT4 KDR

9.68e-06363224713547
Pubmed

Identification and characterization of two members of a novel class of the interleukin-1 receptor (IL-1R) family. Delineation of a new class of IL-1R-related proteins based on signaling.

IL1RAPL1 IL1RAPL2

9.68e-06363210882729
Pubmed

Foretinib inhibits angiogenesis, lymphangiogenesis and tumor growth of pancreatic cancer in vivo by decreasing VEGFR-2/3 and TIE-2 signaling.

FLT4 KDR

9.68e-06363225909285
Pubmed

The inhibition of tyrosine kinase receptor signalling in leiomyosarcoma cells using the small molecule kinase inhibitor PTK787/ZK222584 (Vatalanib®).

FLT4 KDR

9.68e-06363225340839
Pubmed

The specificity of receptor binding by vascular endothelial growth factor-d is different in mouse and man.

FLT4 KDR

9.68e-06363211279005
Pubmed

Autotaxin and vascular endothelial growth factor receptor-2 and -3 are related to vascular development during the progression of chronic viral hepatitis C.

FLT4 KDR

9.68e-06363230456868
Pubmed

Signaling via vascular endothelial growth factor receptors.

FLT4 KDR

9.68e-06363210579917
Pubmed

Impact of vascular endothelial growth factor receptor 1, 2, and 3 expression on the outcome of patients with gastric cancer.

FLT4 KDR

9.68e-06363219068081
Pubmed

Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization.

FLT4 KDR

9.68e-06363221130043
Pubmed

Involvement of vascular endothelial growth factor receptor-3 in maintenance of integrity of endothelial cell lining during tumor angiogenesis.

FLT4 KDR

9.68e-06363210887117
Pubmed

Expression profiling and significance of VEGF-A, VEGFR2, VEGFR3 and related proteins in endometrial carcinoma.

FLT4 KDR

9.68e-06363224845798
Pubmed

Impact of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) single nucleotide polymorphisms on outcome in gastroenteropancreatic neuroendocrine neoplasms.

FLT4 KDR

9.68e-06363229787601
Pubmed

All three receptors for vascular endothelial growth factor (VEGF) are expressed on B-chronic lymphocytic leukemia (CLL) cells.

FLT4 KDR

9.68e-06363214687619
Pubmed

Evaluation of epigenetic inactivation of vascular endothelial growth factor receptors in head and neck squamous cell carcinoma.

FLT4 KDR

9.68e-06363228718364
Pubmed

Possible genetic predisposition to lymphedema after breast cancer.

FLT4 KDR

9.68e-06363222404826
Pubmed

Expression of receptors for VEGFs on normal human thyroid follicular cells and their role in follicle formation.

FLT4 KDR

9.68e-06363221751212
Pubmed

Multiple forms of mouse vascular endothelial growth factor-D are generated by RNA splicing and proteolysis.

FLT4 KDR

9.68e-06363211574540
Pubmed

Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4).

FLT4 KDR

9.68e-0636329435229
Pubmed

uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis.

FLT4 KDR

9.68e-06363230518756
Pubmed

Single-cell transcriptomic analysis of mouse neocortical development.

FLT4 P2RY12 NXPH1 SLC6A20 NXPH3

1.47e-0517063530635555
Pubmed

VEGFR3 modulates brain microvessel branching in a mouse model of 22q11.2 deletion syndrome.

FLT4 KDR

1.93e-05463236216515
Pubmed

Phase I dose escalation study of telatinib, a tyrosine kinase inhibitor of vascular endothelial growth factor receptor 2 and 3, platelet-derived growth factor receptor beta, and c-Kit, in patients with advanced or metastatic solid tumors.

FLT4 KDR

1.93e-05463219636022
Pubmed

LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength.

LRRC8E LRRC8A

1.93e-05463226824658
Pubmed

[Comparative immunohistochemical evaluation of vascular endothelial growth factor and its receptors in the placental villi in gestational diabetes mellitus and type 1 diabetes].

FLT4 KDR

1.93e-05463224341227
Pubmed

Ovarian hyperstimulation syndrome is correlated with a reduction of soluble VEGF receptor protein level and a higher amount of VEGF-A.

FLT4 KDR

1.93e-05463222016416
Pubmed

VEGFR3 does not sustain retinal angiogenesis without VEGFR2.

FLT4 KDR

1.93e-05463225561555
Pubmed

Somatic mutation of vascular endothelial growth factor receptors in juvenile hemangioma.

FLT4 KDR

1.93e-05463211807987
Pubmed

The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPδ and RhoGAP2.

IL1RAPL1 IL1RAPL2

1.93e-05463221926414
Pubmed

Differential expression of VEGF ligands and receptors in prostate cancer.

FLT4 KDR

1.93e-05463223038639
Pubmed

VEGFR3 Modulates Vascular Permeability by Controlling VEGF/VEGFR2 Signaling.

FLT4 KDR

1.93e-05463228298294
Pubmed

Hypocretinergic interactions with the serotonergic system regulate REM sleep and cataplexy.

SLC6A4 HCRTR1

1.93e-05463233247179
Pubmed

Lymphatic ontogeny and effect of hypoplasia in developing lung.

FLT4 KDR

1.93e-05463220932899
Pubmed

VEGFR3 is required for button junction formation in lymphatic vessels.

FLT4 KDR

1.93e-05463237454290
Pubmed

Selective transport of neurotransmitters and modulators by distinct volume-regulated LRRC8 anion channels.

LRRC8E LRRC8A

1.93e-05463228193731
Pubmed

Pro- and antiangiogenic VEGF and its receptor status for the severity of diabetic retinopathy.

FLT4 KDR

1.93e-05463228680264
Pubmed

LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP.

LRRC8E LRRC8A

1.93e-05463233171122
Pubmed

Renal Deletion of LRRC8/VRAC Channels Induces Proximal Tubulopathy.

LRRC8E LRRC8A

3.22e-05563235777784
Pubmed

Recurrent CIC Gene Abnormalities in Angiosarcomas: A Molecular Study of 120 Cases With Concurrent Investigation of PLCG1, KDR, MYC, and FLT4 Gene Alterations.

FLT4 KDR

3.22e-05563226735859
Pubmed

Protein expression profiling of vascular endothelial growth factor and its receptors identifies subclasses of hepatocellular carcinoma and predicts survival.

FLT4 KDR

3.22e-05563219066962
Pubmed

Vascular endothelial growth factor-C derived from CD11b+ cells induces therapeutic improvements in a murine model of hind limb ischemia.

FLT4 KDR

3.22e-05563223219511
Pubmed

LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins.

LRRC8E LRRC8A

3.22e-05563215094057
Pubmed

Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.

LRRC8E LRRC8A

3.22e-05563224790029
Pubmed

Immunolocalization and expression of vascular endothelial growth factor receptors (VEGFRs) and neuropilins (NRPs) on keratinocytes in human epidermis.

FLT4 KDR

3.22e-05563217088944
Pubmed

RNAi-mediated silencing of VEGF-C inhibits non-small cell lung cancer progression by simultaneously down-regulating the CXCR4, CCR7, VEGFR-2 and VEGFR-3-dependent axes-induced ERK, p38 and AKT signalling pathways.

FLT4 KDR

3.22e-05563221680174
Pubmed

Pharmacogenetics of telatinib, a VEGFR-2 and VEGFR-3 tyrosine kinase inhibitor, used in patients with solid tumors.

FLT4 KDR

3.22e-05563219924384
Pubmed

VEGFR2 but not VEGFR3 governs integrity and remodeling of thyroid angiofollicular unit in normal state and during goitrogenesis.

FLT4 KDR

3.22e-05563228438786
Pubmed

VEGF-C is required for intestinal lymphatic vessel maintenance and lipid absorption.

FLT4 KDR

3.22e-05563226459520
Pubmed

Expression level, tissue distribution pattern, and prognostic impact of vascular endothelial growth factors VEGF and VEGF-C and their receptors Flt-1, KDR, and Flt-4 in different subtypes of non-Hodgkin lymphomas.

FLT4 KDR

3.22e-05563219701853
Pubmed

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia.

FLT4 KDR

4.82e-05663212810700
Pubmed

The Schlemm's canal is a VEGF-C/VEGFR-3-responsive lymphatic-like vessel.

FLT4 KDR

4.82e-05663225061878
Pubmed

The role of RNA interference in the developmental separation of blood and lymphatic vasculature.

FLT4 KDR

4.82e-05663224690185
Pubmed

A new chemical probe for quantitative proteomic profiling of fibroblast growth factor receptor and its inhibitors.

FLT4 KDR

4.82e-05663224184958
Pubmed

Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3.

FLT4 KDR

4.82e-05663220065093
Pubmed

Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling.

FLT4 KDR

4.82e-05663222426001
Pubmed

VEGF-C signaling pathways through VEGFR-2 and VEGFR-3 in vasculoangiogenesis and hematopoiesis.

FLT4 KDR

4.82e-05663211090062
Pubmed

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium.

FLT4 KDR

4.82e-0566327596436
Pubmed

Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development.

FLT4 KDR

4.82e-05663220439428
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

TMEM161A SCAP FANCI TMEM161B TUT7 LRRC8A PSMD2 LMBRD2 STT3A GPR107

5.62e-051201631035696571
Pubmed

Transgenic mouse models in angiogenesis and cardiovascular disease.

FLT4 KDR

6.74e-05763210685072
Pubmed

Spatial regulation of VEGF receptor endocytosis in angiogenesis.

FLT4 KDR

6.74e-05763223354168
Pubmed

Membrane fixation of vascular endothelial growth factor receptor 1 ligand-binding domain is important for vasculogenesis and angiogenesis in mice.

FLT4 KDR

8.98e-05863215601855
Pubmed

Mechanoinduction of lymph vessel expansion.

FLT4 KDR

8.98e-05863222157817
Pubmed

The cardiopharyngeal mesoderm contributes to lymphatic vessel development in mouse.

FLT4 KDR

8.98e-05863236196867
Pubmed

Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression.

FLT4 KDR

1.15e-04963217948123
Pubmed

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation.

FLT4 KDR

1.15e-04963218594512
CytobandXp22.1-p21.3

IL1RAPL1 POLA1

5.55e-063632Xp22.1-p21.3
GeneFamilyVolume regulated anion channel subunits

LRRC8E LRRC8A

6.58e-0554721158
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL1RAPL1 IL1RAPL2 IL22RA1

1.76e-0442473602
GeneFamilyX-linked mental retardation|Angiotensin receptors

IL1RAPL1 ZDHHC15 AP1S2

3.52e-0453473103
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL1RAPL1 IL1RAPL2

6.80e-04154721296
GeneFamilyImmunoglobulin like domain containing

IL1RAPL1 FLT4 IL1RAPL2 KDR

1.57e-03193474594
GeneFamilyReceptor Tyrosine Kinases|CD molecules

FLT4 KDR

4.84e-0340472321
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

IL1RAPL1 FLT4 KDR

8.44e-03161473593
ToppCellfacs-Kidney-nan-3m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 SLC12A1 P2RY12 LRRC8A SERINC3 KDR

2.26e-071826364c5d14e33ebdf117b5aa9e2f57aaa89aa51f72bf
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

IL1RAPL1 NXPH1 AP1S2 OPN5 KDR NXPH2

3.94e-07200636ca5401b76ab014080914bf78042d368cf318effa
ToppCelldistal-Endothelial-Capillary_Intermediate_1-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FZD4 SLC6A4 FLT4 LRRC8A KDR NXPH3

3.94e-0720063643bc48413b100a06f8edd9acd812296788fcbf5b
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1|Neuronal / cells hierarchy compared to all cells using T-Statistic

IL1RAPL1 NXPH1 AP1S2 OPN5 KDR NXPH2

3.94e-0720063640286010bd17cf9e34ecd5440953b072ebfae208
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2--L1-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

IL1RAPL1 ATP8A2 NXPH1 AP1S2 OPN5 NXPH2

3.94e-07200636f268cb1bb047e88913a828614b0a77871f5f8814
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

IL1RAPL1 ATP8A2 NXPH1 AP1S2 OPN5 NXPH2

3.94e-072006367345cc7dc24b9174541a3e68ecac8c4c092be400
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2|Neuronal / cells hierarchy compared to all cells using T-Statistic

IL1RAPL1 ATP8A2 NXPH1 AP1S2 OPN5 NXPH2

3.94e-072006365ff9ac97ef970b3b74ebb07f62a0a1f4176a10b4
ToppCelldistal-Endothelial-Capillary_Intermediate_1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FZD4 SLC6A4 FLT4 LRRC8A KDR NXPH3

3.94e-072006364d6714d48738cdee7d535923f6dd2431e5304741
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-CA1--L2-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

IL1RAPL1 NXPH1 AP1S2 OPN5 KDR NXPH2

3.94e-0720063670c47d3bbe67d88c5b9dff99c33a603d25fa2ab0
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)|Neuronal / cells hierarchy compared to all cells using T-Statistic

IL1RAPL1 ATP8A2 NXPH1 AP1S2 OPN5 NXPH2

3.94e-07200636e90155498397524b812c46f2412320230b445bb6
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175|Adult / Lineage, Cell type, age group and donor

FZD4 SLC6A4 IL1RAPL1 FLT4 KDR

5.96e-061826358b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_C1QL2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 KDR NXPH2

6.45e-061856356e7fefdd65d30abaffb26b92b0d04e1630d262ad
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Adult / Lineage, Cell type, age group and donor

FZD4 SLC6A4 IL1RAPL1 FLT4 KDR

6.97e-06188635e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 KDR NXPH2

6.97e-061886353139540a656c0436b2123ea50741ff8d00112165
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 KDR NXPH2

7.16e-06189635979b7fa947538aa7ca4a219263da2575869a2caa
ToppCellfacs-Liver-Non-hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 SGMS1 SERINC3 KDR ARMCX4

7.92e-061936358084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCellfacs-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 FLT4 SGMS1 SERINC3 KDR

8.33e-061956357f9b7f15006610ad591063d90e90367bd6083c7f
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 SGMS1 SERINC3 KDR ARMCX4

8.75e-06197635deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 SGMS1 SERINC3 KDR ARMCX4

8.75e-06197635a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 SGMS1 SERINC3 KDR ARMCX4

8.97e-06198635f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCellmedial-2-Endothelial-Capillary_Intermediate_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FZD4 SLC6A4 FLT4 LRRC8A KDR

9.41e-06200635a8adf5902540f6bb15b72efbb9c389b59d67e001
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FZD4 FLT4 LRRC8A SERINC3 KDR

9.41e-06200635bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellControl_saline-Endothelial-Endothelial-Alv_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

FZD4 SLC6A4 FLT4 SERINC3 KDR

9.41e-06200635abf4ba5fcb54cdeada0da1a8b956a30aa47679e4
ToppCellParenchymal-10x3prime_v2-Endothelial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FZD4 SLC6A4 FLT4 LRRC8A KDR

9.41e-062006353b07cf1a4dff2e868f52382681a2030c1248caed
ToppCellmedial-Endothelial-Capillary_Intermediate_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FZD4 SLC6A4 FLT4 LRRC8A KDR

9.41e-062006353ef7b7728615710c691aed8977e2582f19692cf9
ToppCelldistal-2-Endothelial-Capillary_Intermediate_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FZD4 SLC6A4 FLT4 LRRC8A KDR

9.41e-062006357a99f28670ffb8ece7873d8a9bcd2a3936d0255d
ToppCellmedial-Endothelial-Capillary_Intermediate_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FZD4 SLC6A4 FLT4 LRRC8A KDR

9.41e-06200635707148e01e961097819a05437a842b7d3bf72b0a
ToppCellEndothelial-G|World / shred on cell class and cell subclass (v4)

MOXD2P FLT4 ATP8A2 KDR

2.89e-051246344b72809463f2986b7d1b7ab9de633ac4d7854a92
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

IL1RAPL2 NXPH1 PCDHAC2 NXPH2

5.32e-051456348b13b576fd2e6e33ccb146860a91a53cee0cdd4d
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

P2RY12 POLA1 FANCI SERINC3

7.61e-05159634c0e55f25271f788c08fa4b95186501fc27b2ec39
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 IL1RAPL2 NXPH1 AP1S2

8.18e-05162634d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 IL1RAPL2 NXPH1 AP1S2

8.18e-05162634eed223e61c8162a2fe004ab4e09de5e037be7553
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 IL1RAPL2 NXPH1 AP1S2

8.18e-051626345bbd7130d4dad9035e73a439dda568195c136f31
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 IL1RAPL2 NXPH1 AP1S2

8.18e-05162634e35ddce830e20ebeac1a2c405293fc4a5323dd4a
ToppCell356C-Lymphocytic-ILC-ILC-3|ILC / Donor, Lineage, Cell class and subclass (all cells)

TMEM161B TUT7 AACS

8.89e-0561633d0b33a48ee2faf68b270f9279c630437f3e8b20b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 P2RY12 IL1RAPL2 AP1S2

8.98e-05166634f742d15b02a6f651bbd00f53e3d871f40d05a03d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 P2RY12 IL1RAPL2 AP1S2

8.98e-05166634e941df9a1091164edde3def8fc7d410186b2bd88
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 P2RY12 IL1RAPL2 AP1S2

8.98e-05166634aeda46bea5d8463c24a83b98b9ed92d962d733e5
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Tpbg|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NDST3 IL1RAPL2 NXPH1 NXPH2

8.98e-05166634b4241f8d2a0aa910dbb0d0d5d3631a9b73453fe9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Neural|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 P2RY12 IL1RAPL2 AP1S2

8.98e-051666340f013bb5fdb72e88c2fc73d60cd01551a2db6341
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)|368C / Donor, Lineage, Cell class and subclass (all cells)

SGMS1 POLA1 ATP8A2 IL22RA1

9.41e-051686341bc6a1915d48f547385ed4f44e118bcc8a4a7b6c
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|368C / Donor, Lineage, Cell class and subclass (all cells)

SGMS1 POLA1 ATP8A2 IL22RA1

9.41e-0516863469f534de0f9a293047bea03cb1b78551087a8df5
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SGMS1 POLA1 ATP8A2 IL22RA1

9.41e-05168634c66a61d3ec711796313a2c6d2dc39aedbfc20afd
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

IL1RAPL1 FRMD4A IL1RAPL2 AP1S2

9.41e-0516863488c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SGMS1 POLA1 ATP8A2 IL22RA1

9.41e-0516863483b4f817d95daa15ae60668e789f97d8a3b2e6dd
ToppCellEndothelial-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

NDST3 FLT4 KDR NXPH3

9.63e-051696348889c9e8af1ab0b093d57b69abd80b59b3461be9
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FRMD4A ZDHHC15 POLA1 FANCI

1.03e-041726342b6cd84c946b1e800caba452ae70145ea285fec1
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FANCI LRRC8A KDR NXPH3

1.03e-0417263494093d356b0252b440deda4e1b0ac332b31513f6
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND01-03-samps / Age Group, Lineage, Cell class and subclass

FZD4 PCDHAC2 ZNF407 KDR

1.08e-04174634cb0109661e8c9ca04d67d33f2d926f0e649bf67d
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

FZD4 IL1RAPL1 FLT4 KDR

1.23e-04180634b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

FZD4 SLC6A4 FLT4 KDR

1.25e-04181634c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FZD4 IL1RAPL1 FLT4 KDR

1.28e-04182634a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

FLT4 SERINC3 KDR ARMCX4

1.28e-041826347af3b2029b7f55b923d5a4b764d4292f4ea48599
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NDST3 NXPH1 OPN5 NXPH2

1.28e-04182634f00eec1f434d92d44787d3d3343476c98c3de5b4
ToppCellE18.5-samps-Endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

FLT4 SERINC3 KDR ARMCX4

1.28e-04182634e2d799e6e7526176a6fe6515b8fbe4d83d3a3ea1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 POLA1 FANCI KDR

1.34e-04184634688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 OPN5 KDR NXPH2

1.34e-04184634ae0a77e3e520a246b17776bb19503519636b02ee
ToppCellfacs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDELR2 FLT4 P2RY12 LRRC8A

1.34e-04184634af5eb3650fafc808828eb42f68c0f1e9c278adbb
ToppCellfacs-Lung-Endomucin-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDELR2 FLT4 P2RY12 LRRC8A

1.36e-04185634f262b441ea3fe7f69dff33d5f171000371f3a3e5
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRRC8E IL1RAPL1 NXPH1 GPR162

1.39e-04186634bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCellmild-Lymphocytic-Plasmablast|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PREB KDELR2 STT3A CCNC

1.39e-04186634060510c21b1e0889b7a6eeb15821b9e2f03a0f99
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 OPN5 KDR NXPH2

1.39e-0418663477592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCellfacs-Spleen-nan-3m-Lymphocytic-CD79a_B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCHSD2 SGMS1 P2RY12 SERINC3

1.42e-04187634b51af2824e65734f333b1325117f4a2e88b17c23
ToppCellfacs-Spleen-nan-3m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCHSD2 SGMS1 P2RY12 SERINC3

1.42e-041876343ca3954f45f167e98a230f2847f0582d74fcd32e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 NXPH2

1.45e-041886348268574584e5fb869a6cb8bbd7135cd7454a6a25
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 NXPH2

1.45e-041886340501a8aa850bd2e347020abd1cac4d8075738189
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 NXPH2

1.45e-041886344544552ebd67e9eb3e40d8511bb2b03a6e1178f8
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 NXPH2

1.48e-04189634222e67d3fd106c43b0cae6538dddeaa7be1f759f
ToppCellLAM-Endothelial-VasEndo-1|LAM / Condition, Lineage and Cell class

FZD4 SLC6A4 FLT4 KDR

1.48e-04189634454e64b1ee93edebbc1576fbf7c3a6db332fa927
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P2RY12 ATP8A2 SERINC3 STT3A

1.48e-041896346dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P2RY12 ATP8A2 SERINC3 STT3A

1.48e-041896343ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P2RY12 ATP8A2 SERINC3 STT3A

1.48e-04189634875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCellfacs-Brain_Myeloid-Striatum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P2RY12 ATP8A2 SERINC3 STT3A

1.48e-0418963497ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FZD4 SLC6A4 IL1RAPL1 KDR

1.51e-041906340a351609a72fd638c84b2435782e312ee6a33aac
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 OPN5 KDR NXPH2

1.51e-041906342f54da2bee411f8868348a4c37034184b8f58a89
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 NXPH2

1.51e-041906343b8d1e66ae68c1eee64095e75195d76d97e24026
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 NXPH2

1.51e-0419063456cc761e50fddfb5366391518b4d8e16589b6b42
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 NXPH2

1.51e-0419063459720dfe9de1b980807644536c919d2a02ba69dd
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 NXPH2

1.51e-04190634be2b184a3559da41ba387ae0fdbeb9ae532868a5
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 NXPH2

1.51e-04190634dc655e4782aab274f0c9b6e36a5ce315e3a1a4b9
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 NXPH2

1.51e-0419063425d4b591f75c26e404a34c42f1742d580af6598d
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

FZD4 SLC6A4 IL1RAPL1 KDR

1.54e-04191634f229abf69a1217194f74b0502486907e07dba989
ToppCellfacs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 ATP8A2 SERINC3 KDR

1.54e-0419163448823a97c38263f2c6e58348214f5b62773a6368
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 ATP8A2 SERINC3 KDR

1.54e-041916340eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial-endothelial_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 LRRC8A SERINC3 KDR

1.57e-041926340986b7900021efe2a4df84a935e7c9a0af1b0e57
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 NXPH2

1.57e-04192634bd3fa6c8fcb618db64d11f25cabaf08608957c35
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 FLT4 SGMS1 KDR

1.57e-041926349ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 NXPH2

1.57e-04192634f6ec683b2133b3095a1fcc06ca8605cf38f774b5
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 NXPH2

1.57e-04192634690b3d17c481159bc96b8bc7f6a66b51343ee858
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 LRRC8A SERINC3 KDR

1.57e-041926348f20d3511dcb44445592b17d005a53da0052ae56
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 FLT4 SGMS1 KDR

1.57e-04192634a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCellfacs-Lung-Endomucin_-18m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 SGMS1 LRRC8A KDR

1.57e-04192634ba3fe97786564dba1c8185f2802ce1b57f4f3cc9
ToppCellEndothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|World / Lineage, Cell type, age group and donor

FZD4 SLC6A4 FLT4 KDR

1.57e-041926341e156bab5ecf64627890d2de9b27603d9a01f28d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 NXPH2

1.57e-0419263463d1b3efe93e5ff939278ebe40bacb38218ea09b
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 LRRC8A SERINC3 KDR

1.57e-04192634b28d294e42b303d1db6060231d84d7b9e4d9fccf
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 FLT4 SGMS1 KDR

1.57e-0419263466defad13bd8e79319741e43ddb056841710b1d7
ToppCellfacs-Lung-Endomucin_|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 SGMS1 LRRC8A KDR

1.57e-0419263485d4d0df701451daf95e94a87a0096da1e86533b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NXPH1 AP1S2 OPN5 NXPH2

1.57e-04192634342842378c20267c5044bdd622515e8b9f895623
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDELR2 FCHSD2 P2RY12 SERINC3

1.60e-0419363406b65110db974f4ef90d3511ff34428976a52c9c
ToppCellE15.5-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FZD4 FLT4 SERINC3 KDR

1.60e-041936349f4ffce4e1440b009b0b5947ebf52b12a644704d
ComputationalNeighborhood of CCNF

POLA1 FANCI NUDT13

7.54e-0478253MORF_CCNF
ComputationalPeptide and AA transporters.

SLC6A4 SLC12A1

7.77e-0418252MODULE_368
ComputationalGenes in the cancer module 162.

SLC6A4 SLC12A1

8.67e-0419252MODULE_162
ComputationalGenes in the cancer module 218.

SLC6A4 SLC12A1

9.62e-0420252MODULE_218
Diseaselymphangioma (is_marker_for)

FLT4 KDR

4.20e-062612DOID:1475 (is_marker_for)
DiseaseHEMANGIOMA, CAPILLARY INFANTILE, SOMATIC

FLT4 KDR

4.20e-062612C4016109
DiseaseHEMANGIOMA, CAPILLARY INFANTILE

FLT4 KDR

1.26e-053612602089
DiseaseCapillary infantile hemangioma

FLT4 KDR

1.26e-053612cv:C1865871
DiseaseHEMANGIOMA, CAPILLARY INFANTILE

FLT4 KDR

1.26e-053612C1865871
Diseasethyroid gland carcinoma (is_marker_for)

FLT4 KDR

2.74e-0412612DOID:3963 (is_marker_for)
Diseasechildhood trauma measurement

NDST3 IL1RAPL1

1.13e-0324612EFO_0007979
Diseasecarnosine measurement

FRMD4A HCRTR1

1.13e-0324612EFO_0010470
Diseasetransforming growth factor beta measurement

NXPH1 CUL9

1.43e-0327612EFO_0004818
Diseaseresponse to serotonin-norephinephrine reuptake inhibitor

FCHSD2 NXPH1

2.53e-0336612EFO_0006325

Protein segments in the cluster

PeptideGeneStartEntry
YFYTVNRYCIIRSSK

GRAMD1C

431

Q8IYS0
YLTARSTYYVCKVER

CXorf65

66

A6NEN9
AQSYEYVYRCIKSSI

AACS

416

Q86V21
TCCYFKFIIEYYNIR

FBXO34

601

Q9NWN3
CYYIYKFTKGRAQSV

ARMCX4

21

Q5H9R4
SYNRVTKCILYCFYK

ATP8A2

871

Q9NTI2
TKCILYCFYKNVVLY

ATP8A2

876

Q9NTI2
ICIYIAFYSVDYKLV

NXPH2

231

O95156
FCMVSIIISAYYLYS

NDST3

21

O95803
HYYVLIVCYIYFTRI

GPR107

496

Q5VW38
LYICDLSTYKVYSFC

KBTBD3

511

Q8NAB2
KVIKFILIICYTVYY

LRRC8A

271

Q8IWT6
TVYFKRFYARYSLKS

CCNC

66

P24863
IVYKRYASLYFCCAI

AP1S2

56

P56377
LCKMYTTLTALVRYY

FANCI

1166

Q9NVI1
KVFVSTYYTLALATC

GPR162

91

Q16538
IKCALFYGYIRTNYS

IL1RAPL1

51

Q9NZN1
AVSLDRYLKICYLSY

OPN5

126

Q6U736
YISFVCIYGLTCIYT

LRRC8E

316

Q6NSJ5
CYLYTERLTTAIYLY

METTL15P1

206

P0C7V9
YFYIITYLFFKTRSC

OR12D2

216

P58182
IVCYTLITKELYRSY

P2RY12

206

Q9H244
VSKTVCSTYLQSRYY

HIPK3

351

Q9H422
CYRLLSTYVTKTRYL

NUDT13

16

Q86X67
KSLYTQLCFYRYIFD

POLA1

1386

P09884
LSIIKCYRYTAYGTA

PCDHAC2

726

Q9Y5I4
YPKIYHSCFFIVTYL

HCRTR1

211

O43613
CYNIYSIAYIVRLTV

FZD4

261

Q9ULV1
YFCVRFYIESISYLK

FRMD4A

96

Q9P2Q2
TVLYTLSDYTTCLYF

CABIN1

166

Q9Y6J0
FLVAVLCYLSYRYVT

IL22RA1

241

Q8N6P7
QARKVLAYACVYSFY

CUL9

2341

Q8IWT3
TLRNYPLTCKVVYSY

FCHSD2

466

O94868
TYIILFAYIYFSTRK

SCAP

291

Q12770
IYLACSYATVYLIYL

KDELR2

66

P33947
VFIYVLYIISSIYGC

PTCHD3

606

Q3KNS1
TAIILFYATCIYTYL

OR5F1

246

O95221
SSGIRVYYTSQLCKY

MOXD2P

321

A6NHM9
FKVVCVYIAFYSTDY

NXPH3

216

O95157
RVYCYVTVVSLQYLT

TMEM161A

366

Q9NX61
RVFYYLCVIALQYVA

TMEM161B

366

Q8NDZ6
TYPFCTYYFVLSIIV

LIPI

331

Q6XZB0
KTYNYIYIEIACFLS

LMBRD2

426

Q68DH5
KVICIYISFYSTDYK

NXPH1

236

P58417
YAKVCLYLTSCVNYV

PSMD2

226

Q13200
VKCALFYSYIRTNYS

IL1RAPL2

51

Q9NP60
IYVAYCTVYCLGTIL

STT3A

236

P46977
TYVIEFFLYVYVTCK

SLC12A1

631

Q13621
ILCCIVLVAYSYTYI

OR6J1

206

Q8NGC5
VYFTASLPYCVLIIY

SLC6A20

196

Q9NP91
AYVYRVIRTTAYLLY

CNGB1

786

Q14028
SYIRCYYFAVKTLIT

CNGB1

831

Q14028
VFQRLAAVLYCYFYK

TMEM138

121

Q9NPI0
AAVLYCYFYKRTAVR

TMEM138

126

Q9NPI0
IYIAFSLQCLYYVRE

PREB

326

Q9HCU5
KFLLCVILFYTVYYV

TMEM244

16

Q5VVB8
TGSYVCYYKYIKARI

FLT4

106

P35916
TLYLYRCITMYVTTL

SGMS1

221

Q86VZ5
LSIICVGLLYTYYTK

SERINC3

216

Q13530
YLIEFCYTIAQKYLF

ZMYND12

86

Q9H0C1
YKCFYRETDLASVIY

KDR

101

P35968
QYSYLCKVCKYYTVT

ZNF407

876

Q9C0G0
EYILHCLRTTYKYFA

TUT7

616

Q5VYS8
IGYAICIIAFYIASY

SLC6A4

161

P31645
YYAYVFELCLVTVLS

ZDHHC15

36

Q96MV8
SVLYCLYIATTVFSY

ZDHHC15

181

Q96MV8
RFSYVFYLSCHKIRY

NLRP13

261

Q86W25