Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	MAP kinase kinase kinase activity	MAP3K14 MAP3K6 MAP3K5	1.63e-04	27	79	3	GO:0004709
Domain	DIX	DVL1P1 DVL1 AXIN1	2.07e-06	7	74	3	PF00778
Domain	DIX	DVL1P1 DVL1 AXIN1	2.07e-06	7	74	3	IPR001158
Domain	DIX	DVL1P1 DVL1 AXIN1	2.07e-06	7	74	3	PS50841
Domain	DAX	DVL1P1 DVL1 AXIN1	2.07e-06	7	74	3	SM00021
Domain	DVL-1	DVL1P1 DVL1	1.55e-05	2	74	2	IPR008340
Domain	BAT2_N	PRRC2A PRRC2B	4.63e-05	3	74	2	PF07001
Domain	BAT2_N	PRRC2A PRRC2B	4.63e-05	3	74	2	IPR009738
Domain	DUF4071	MAP3K6 MAP3K5	4.63e-05	3	74	2	IPR025136
Domain	DUF4071	MAP3K6 MAP3K5	4.63e-05	3	74	2	PF13281
Domain	PRRC2	PRRC2A PRRC2B	4.63e-05	3	74	2	IPR033184
Domain	Dishevelled_fam	DVL1P1 DVL1	9.24e-05	4	74	2	IPR008339
Domain	Dishevelled	DVL1P1 DVL1	9.24e-05	4	74	2	PF02377
Domain	Dishevelled_protein_dom	DVL1P1 DVL1	9.24e-05	4	74	2	IPR003351
Domain	NUT	NUTM2F NUTM2G	1.54e-04	5	74	2	IPR024310
Domain	NUT_N	NUTM2F NUTM2G	1.54e-04	5	74	2	IPR024309
Domain	NUT	NUTM2F NUTM2G	1.54e-04	5	74	2	PF12881
Domain	MYTH4	MYO15B MYO15A	5.48e-04	9	74	2	PS51016
Domain	MyTH4_dom	MYO15B MYO15A	5.48e-04	9	74	2	IPR000857
Domain	MyTH4	MYO15B MYO15A	5.48e-04	9	74	2	PF00784
Domain	MyTH4	MYO15B MYO15A	5.48e-04	9	74	2	SM00139
Domain	DEP	DVL1P1 DVL1	3.40e-03	22	74	2	PF00610
Domain	DEP	DVL1P1 DVL1	3.40e-03	22	74	2	PS50186
Domain	DEP	DVL1P1 DVL1	3.40e-03	22	74	2	SM00049
Domain	PAS_fold_3	KCNH3 NPAS1	3.71e-03	23	74	2	IPR013655
Domain	DEP_dom	DVL1P1 DVL1	3.71e-03	23	74	2	IPR000591
Domain	PAS_3	KCNH3 NPAS1	3.71e-03	23	74	2	PF08447
Domain	PAS-assoc_C	KCNH3 NPAS1	4.04e-03	24	74	2	IPR000700
Domain	JmjC	KDM6B HR	4.04e-03	24	74	2	PF02373
Domain	PAC	KCNH3 NPAS1	4.73e-03	26	74	2	IPR001610
Domain	PAC	KCNH3 NPAS1	4.73e-03	26	74	2	SM00086
Domain	PAC	KCNH3 NPAS1	4.73e-03	26	74	2	PS50113
Domain	SH3_2	MYO15B MYO15A ARHGAP33	4.83e-03	86	74	3	IPR011511
Domain	SH3_2	MYO15B MYO15A ARHGAP33	4.83e-03	86	74	3	PF07653
Domain	DUSP	KASH5 DUSP15	6.69e-03	31	74	2	IPR024950
Domain	JMJC	KDM6B HR	7.11e-03	32	74	2	PS51184
Domain	PAS	KCNH3 NPAS1	7.11e-03	32	74	2	SM00091
Domain	JmjC_dom	KDM6B HR	7.11e-03	32	74	2	IPR003347
Domain	JmjC	KDM6B HR	7.55e-03	33	74	2	SM00558
Pathway	BIOCARTA_PS1_PATHWAY	DVL1 AXIN1	5.98e-04	14	37	2	MM1459
Pathway	BIOCARTA_PS1_PATHWAY	DVL1 AXIN1	5.98e-04	14	37	2	M16173
Pathway	BIOCARTA_PITX2_PATHWAY	DVL1 AXIN1	6.89e-04	15	37	2	MM1439
Pathway	BIOCARTA_PITX2_PATHWAY	DVL1 AXIN1	7.86e-04	16	37	2	M8516
Pathway	WP_INSULIN_SIGNALING	MAP3K14 MAP3K6 ARHGAP33 MAP3K5	7.88e-04	160	37	4	M39482
Pathway	WP_INSULIN_SIGNALING	MAP3K14 MAP3K6 ARHGAP33 MAP3K5	7.88e-04	160	37	4	MM15956
Pathway	REACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA	TUT4 DUX4	8.89e-04	17	37	2	M48025
Pathway	PID_BETA_CATENIN_DEG_PATHWAY	DVL1 AXIN1	9.99e-04	18	37	2	M31
Pathway	BIOCARTA_MAPK_PATHWAY	MAP3K14 MAP3K6 MAP3K5	1.03e-03	76	37	3	MM1433
Pathway	BIOCARTA_MAPK_PATHWAY	MAP3K14 MAP3K6 MAP3K5	1.23e-03	81	37	3	M13863
Pathway	PID_WNT_CANONICAL_PATHWAY	DVL1 AXIN1	1.24e-03	20	37	2	M90
Pathway	BIOCARTA_GSK3_PATHWAY	DVL1 AXIN1	1.24e-03	20	37	2	M11106
Pubmed	Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element.	DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	5.41e-19	12	87	8	10433963
Pubmed	Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy.	DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	1.40e-18	13	87	8	17668377
Pubmed	The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	3.82e-18	8	87	7	17588759
Pubmed	DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	5.71e-17	10	87	7	17984056
Pubmed	Characterization of a tandemly repeated 3.3-kb KpnI unit in the facioscapulohumeral muscular dystrophy (FSHD) gene region on chromosome 4q35.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	8.12e-16	13	87	7	7739628
Pubmed	Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	9.13e-15	17	87	7	11245978
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FAM193B KMT2C TNRC18 B4GALNT4 SCAP SZT2 PPRC1 DVL1 KDM6B MYRF SOWAHB ARHGAP33 PRRC2B KCNH3 MAP3K5 HR	1.38e-08	1105	87	16	35748872
Pubmed	Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development.	DUX4L9 DUX4L2 DUX4L4	6.04e-08	4	87	3	17911620
Pubmed	The homeobox transcription factor DUXBL controls exit from totipotency.	DUX4L9 DUX4L2 DUX4L4	6.04e-08	4	87	3	38509386
Pubmed	Characterization of genomic structures and expression profiles of three tandem repeats of a mouse double homeobox gene: Duxbl.	DUX4L9 DUX4L2 DUX4L4	1.51e-07	5	87	3	20063414
Pubmed	The transcription factor Duxbl mediates elimination of pre-T cells that fail β-selection.	DUX4L9 DUX4L2 DUX4L4	5.25e-07	7	87	3	30765463
Pubmed	Genome-Wide Association Study of the Genetic Determinants of Emphysema Distribution.	JCAD SOWAHB	6.19e-06	2	87	2	27669027
Pubmed	Coexpression and protein-protein complexing of DIX domains of human Dvl1 and Axin1 protein.	DVL1 AXIN1	6.19e-06	2	87	2	20846493
Pubmed	Defective regulation of microRNA target genes in myoblasts from facioscapulohumeral dystrophy patients.	DUX4L9 DUX4	6.19e-06	2	87	2	24145033
Pubmed	ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis.	MAP3K6 MAP3K5	6.19e-06	2	87	2	19214184
Pubmed	Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1.	MAP3K6 MAP3K5	6.19e-06	2	87	2	17210579
Pubmed	Human homologue sequences to the Drosophila dishevelled segment-polarity gene are deleted in the DiGeorge syndrome.	DVL1P1 DVL1	6.19e-06	2	87	2	8644734
Pubmed	MAPKKK6, a novel mitogen-activated protein kinase kinase kinase, that associates with MAPKKK5.	MAP3K6 MAP3K5	6.19e-06	2	87	2	9875215
Pubmed	Proteomic analysis identifies transcriptional cofactors and homeobox transcription factors as TBX18 binding proteins.	DUX4L9 DUX4L2 DUX4L4	6.73e-06	15	87	3	30071041
Pubmed	MAP3Ks as central regulators of cell fate during development.	MAP3K14 MAP3K6 MAP3K5	6.73e-06	15	87	3	18855897
Pubmed	Mutations in MINAR2 encoding membrane integral NOTCH2-associated receptor 2 cause deafness in humans and mice.	DUX4L9 DUX4L2 DUX4L4	6.73e-06	15	87	3	35727972
Pubmed	The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response.	MAP3K6 MAP3K5	1.85e-05	3	87	2	26243192
Pubmed	A divergent canonical WNT-signaling pathway regulates microtubule dynamics: dishevelled signals locally to stabilize microtubules.	DVL1 AXIN1	1.85e-05	3	87	2	14734535
Pubmed	Structure-based mechanism of preferential complex formation by apoptosis signal-regulating kinases.	MAP3K6 MAP3K5	1.85e-05	3	87	2	32156783
Pubmed	DUSP15 expression is reduced in the hippocampus of Myrf knock-out mice but attention and object recognition memory remain intact.	DUSP15 MYRF	1.85e-05	3	87	2	36730342
Pubmed	ASK family kinases mediate cellular stress and redox signaling to circadian clock.	MAP3K6 MAP3K5	1.85e-05	3	87	2	29555767
Pubmed	ASK1/2 signaling promotes inflammation in a mouse model of neutrophilic dermatosis.	MAP3K6 MAP3K5	1.85e-05	3	87	2	29629899
Pubmed	β-TrCP-dependent degradation of ASK1 suppresses the induction of the apoptotic response by oxidative stress.	MAP3K6 MAP3K5	3.70e-05	4	87	2	30031111
Pubmed	Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein.	DVL1 AXIN1	3.70e-05	4	87	2	11113207
Pubmed	cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene.	DVL1P1 DVL1	3.70e-05	4	87	2	8817329
Pubmed	Human dishevelled genes constitute a DHR-containing multigene family.	DVL1P1 DVL1	3.70e-05	4	87	2	9192851
Pubmed	Non-canonical Wnt signaling induces ubiquitination and degradation of Syndecan4.	DVL1P1 DVL1	3.70e-05	4	87	2	20639201
Pubmed	Axin-dependent phosphorylation of the adenomatous polyposis coli protein mediated by casein kinase 1epsilon.	DVL1 AXIN1	3.70e-05	4	87	2	11487578
Pubmed	Casein kinase Iepsilon modulates the signaling specificities of dishevelled.	DVL1 AXIN1	3.70e-05	4	87	2	14966280
Pubmed	ASK1 inhibits interleukin-1-induced NF-kappa B activity through disruption of TRAF6-TAK1 interaction.	MAP3K14 MAP3K5	3.70e-05	4	87	2	10921914
Pubmed	ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease.	MAP3K6 MAP3K5	3.70e-05	4	87	2	18327563
Pubmed	DUX4c is up-regulated in FSHD. It induces the MYF5 protein and human myoblast proliferation.	DUX4L9 DUX4	3.70e-05	4	87	2	19829708
Pubmed	Dual engagement of 14-3-3 proteins controls signal relay from ASK2 to the ASK1 signalosome.	MAP3K6 MAP3K5	3.70e-05	4	87	2	19935702
Pubmed	Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1.	DVL1 AXIN1	3.70e-05	4	87	2	10428961
Pubmed	Frizzled-9 is activated by Wnt-2 and functions in Wnt/beta -catenin signaling.	DVL1 AXIN1	6.16e-05	5	87	2	12138115
Pubmed	Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin.	DVL1 AXIN1	6.16e-05	5	87	2	9482734
Pubmed	RNA transcripts, miRNA-sized fragments and proteins produced from D4Z4 units: new candidates for the pathophysiology of facioscapulohumeral dystrophy.	DUX4L2 DUX4	6.16e-05	5	87	2	19359275
Pubmed	Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress.	MAP3K6 MAP3K5	6.16e-05	5	87	2	11689443
Pubmed	SUMOylation target sites at the C terminus protect Axin from ubiquitination and confer protein stability.	DVL1 AXIN1	6.16e-05	5	87	2	18632848
Pubmed	ASK Family Kinases Are Required for Optimal NLRP3 Inflammasome Priming.	MAP3K6 MAP3K5	1.29e-04	7	87	2	29353059
Pubmed	Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin.	DVL1 AXIN1	1.29e-04	7	87	2	12556519
Pubmed	USP42 protects ZNRF3/RNF43 from R-spondin-dependent clearance and inhibits Wnt signalling.	DVL1 AXIN1	1.29e-04	7	87	2	33786993
Pubmed	Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization.	DVL1 AXIN1	1.29e-04	7	87	2	10330403
Pubmed	The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes.	DUSP15 MYRF	1.29e-04	7	87	2	27532821
Pubmed	The DIX domain protein coiled-coil-DIX1 inhibits c-Jun N-terminal kinase activation by Axin and dishevelled through distinct mechanisms.	DVL1 AXIN1	1.29e-04	7	87	2	15262978
Pubmed	A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida.	DVL1 AXIN1	1.29e-04	7	87	2	17681137
Pubmed	A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5).	DVL1P1 DVL1	1.72e-04	8	87	2	19643732
Pubmed	Dual functions of DP1 promote biphasic Wnt-on and Wnt-off states during anteroposterior neural patterning.	DVL1 AXIN1	1.72e-04	8	87	2	22773187
Pubmed	Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome.	SCAP TICAM1	1.72e-04	8	87	2	32516576
Pubmed	LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6.	DVL1 AXIN1	2.20e-04	9	87	2	22899650
Pubmed	RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.	DVL1 AXIN1	2.20e-04	9	87	2	32965059
Pubmed	Regulation of the Wnt signaling pathway by disabled-2 (Dab2).	DVL1 AXIN1	2.20e-04	9	87	2	12805222
Pubmed	Multiplex Chromosomal Exome Sequencing Accelerates Identification of ENU-Induced Mutations in the Mouse.	DUSP15 SOWAHB	2.20e-04	9	87	2	22384391
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	KMT2C KDM6B HR	2.56e-04	49	87	3	34368113
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	DUX4L9 DUX4L2 DUX4L4	2.72e-04	50	87	3	31806660
Pubmed	Mechanisms of Wnt signaling in development.	DVL1 AXIN1	2.75e-04	10	87	2	9891778
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	PRRT3 LMTK3 PRRC2A ARHGAP33 PRRC2B	2.94e-04	231	87	5	16452087
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	GXYLT2 LINC00322 PHF3 ZC3H18 PRRC2A PRRC2B	2.99e-04	361	87	6	26167880
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	KMT2C PHF3 DUX4 LMTK3 AXIN1	3.06e-04	233	87	5	37704626
Pubmed	Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription.	DVL1 AXIN1	3.35e-04	11	87	2	10644691
Pubmed	Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma.	PRRC2A MAP3K5	4.74e-04	13	87	2	17827388
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	FAM193B MYO15B SZT2 DUSP15 IGSF9B ADAMTSL4 GARRE1	4.77e-04	552	87	7	10737800
Pubmed	Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.	ESPNL MYO15A	5.52e-04	14	87	2	26754646
Pubmed	Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.	PHF3 LMTK3	5.52e-04	14	87	2	28263302
Pubmed	Human chromosome 19 and related regions in mouse: conservative and lineage-specific evolution.	KASH5 ARHGAP33	7.26e-04	16	87	2	11441184
Pubmed	Application of gene network analysis techniques identifies AXIN1/PDIA2 and endoglin haplotypes associated with bicuspid aortic valve.	PRRC2A AXIN1	7.26e-04	16	87	2	20098615
Pubmed	The contribution of de novo coding mutations to autism spectrum disorder.	PHF3 KDM6B	9.22e-04	18	87	2	25363768
Pubmed	Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation.	KDM6B MYRF	1.03e-03	19	87	2	23332759
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	KMT2C HAX1	1.14e-03	20	87	2	29785026
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	CMTM5 IGSF9B LMTK3 PRRC2A PRRC2B MAP3K5	1.25e-03	475	87	6	31040226
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KMT2C KDM6B	1.26e-03	21	87	2	27626377
Pubmed	PRRC2B modulates oligodendrocyte progenitor cell development and myelination by stabilizing Sox2 mRNA.	PRRC2A PRRC2B	1.38e-03	22	87	2	38507412
Pubmed	A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity.	TICAM1 MAP3K14	1.51e-03	23	87	2	22761313
Pubmed	Mesenchymal expression of Foxl1, a winged helix transcriptional factor, regulates generation and maintenance of gut-associated lymphoid organs.	MAP3K14 FOXL1	1.51e-03	23	87	2	12648490
Pubmed	Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor.	FAM193B CHERP AXIN1	1.62e-03	92	87	3	20368287
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	DNHD1 KMT2C SZT2 PHF3	1.88e-03	208	87	4	33230847
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	DNHD1 ZNF843 MAP3K14 HAX1 MYO15A	2.21e-03	363	87	5	25036637
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	FNIP2 JCAD KMT2C	2.23e-03	103	87	3	10819331
Interaction	TOP3B interactions	FAM193B KMT2C TNRC18 B4GALNT4 SCAP SZT2 PPRC1 DVL1 KDM6B MYRF ADAMTSL4 PRRC2A SOWAHB ARHGAP33 PRRC2B KCNH3 MAP3K5 FOXL1 HR	2.33e-06	1470	78	19	int:TOP3B
Cytoband	Ensembl 112 genes in cytogenetic band chr4q35	DUX4L9 WWC2-AS2 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	1.44e-12	117	87	9	chr4q35
Cytoband	4q35.2	DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	1.11e-11	27	87	6	4q35.2
Cytoband	16q24	TAF1C FOXL1	4.74e-04	17	87	2	16q24
GeneFamily	PRD class homeoboxes and pseudogenes	DUX4L9 DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	7.78e-09	92	52	7	521
GeneFamily	Myosins, class XV\|Deafness associated genes\|FERM domain containing	MYO15B MYO15A	8.11e-06	2	52	2	1105
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	MAP3K14 MAP3K6 MAP3K5	4.35e-05	24	52	3	654
Drug	Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A	SCAP PHF3 TAF1C MED25 MAP3K6 PRRC2A PRRC2B	7.36e-06	193	84	7	3262_UP
Drug	PNU-0230031 [267429-39-0]; Down 200; 10uM; PC3; HT_HG-U133A	SZT2 TAF1C MED25 KDM6B ZNF783 CYP2W1 HR	7.88e-06	195	84	7	3732_DN
Disease	DiGeorge syndrome (is_implicated_in)	DVL1P1 DVL1	6.69e-05	5	77	2	DOID:11198 (is_implicated_in)
Disease	amphetamine abuse (implicated_via_orthology)	MAP3K6 MAP3K5	1.00e-04	6	77	2	DOID:670 (implicated_via_orthology)
Disease	thioredoxin domain-containing protein 12 measurement	TUT4 SCAP SH2D2A	1.46e-04	39	77	3	EFO_0008298
Disease	phosphatidylcholine 38:3 measurement	LINC00322 MYRF	7.88e-04	16	77	2	EFO_0010385
Disease	response to acetylsalicylate	SCAP SH2D2A	7.88e-04	16	77	2	GO_1903492
Disease	emphysema pattern measurement	JCAD SOWAHB	1.12e-03	19	77	2	EFO_0005850
Disease	pulmonary non-tuberculous mycobacterial infection	SCAP SH2D2A	1.12e-03	19	77	2	MONDO_0018469
Disease	nicotine dependence	DVL1P1 DVL1 HAX1	1.13e-03	78	77	3	EFO_0003768
Disease	arachidonic acid measurement	VGLL3 MYRF	1.94e-03	25	77	2	EFO_0006808

Protein segments in the cluster

Peptide	Gene	Start	Entry
PRLEPDPQHPGAWLP	ADAMTSL4	326	Q6UY14
PPDGALSHPQAPRWP	DUX4L4	246	P0CJ87
LSHPQAPRWPPHPGK	DUX4L4	251	P0CJ87
WPPGPRPLPLVGNLH	CYP2W1	31	Q8TAV3
GRLPLPWRPHAPAGP	DNHD1	4531	Q96M86
PWRPHAPAGPQPPWH	DNHD1	4536	Q96M86
PPDGALSHPQAPRWP	DUX4L6	246	P0CJ89
LSHPQAPRWPPHPGK	DUX4L6	251	P0CJ89
VHSSWNLPPGPFPLP	CYP2E1	26	P05181
WGLAPPGDPPPTLLH	NPAS1	511	Q99742
LGPSPPPTWPHLQLC	KASH5	541	Q8N6L0
VLSGTWPHPRPGPPP	KCNH3	956	Q9ULD8
GPSPFPRPWAPHALP	SLC10A4	81	Q96EP9
LSPAWPGHPDQPLPR	ESPNL	371	Q6ZVH7
GAWTLPSHPPELPGP	HAX1	96	O00165
SPAVPHPGPLQHWQP	KMT2C	2411	Q8NEZ4
PPDGALSHPQAPRWP	DUX4	246	Q9UBX2
LSHPQAPRWPPHPGK	DUX4	251	Q9UBX2
PGAAAAHLPRWPPPQ	KAAG1	31	Q9UBP8
HWSALLSPPVPPRPP	MYO15A	656	Q9UKN7
QPGHPRAWPPSPGRF	JCAD	921	Q9P266
CPPHPPPRSAWLPGG	KDM6B	31	O15054
FPWPWPPAHSAPRPG	LMTK3	431	Q96Q04
PPDGALSHPQAPRWP	DUX4L3	246	P0CJ86
LSHPQAPRWPPHPGK	DUX4L3	251	P0CJ86
LPPEHPCDWPLTPHP	HR	171	O43593
PEPPGGPPRRAHFWL	MAP3K6	491	O95382
PPPIPGPNPHGQHWG	PCED1A	386	Q9H1Q7
HPAPVPARWPGPGAL	GXYLT2	46	A0PJZ3
PGPDVWRIPLGPLPH	POU5F2	56	Q8N7G0
LQPAPEPPAPAPHWA	LRATD1	131	Q96KN4
LGPPLLHPPPAQSWP	MED25	691	Q71SY5
PPRFQPHQGPWGAPS	FAM83A	366	Q86UY5
PWGSPPPPPEQIHSA	GGN	386	Q86UU5
PPHCHMPPGPAGEWP	MYO15B	16	Q96JP2
PPPNSLAHPGAWVPG	ARHGAP33	951	O14559
PRTPHRVPGPWGPPE	ARHGAP33	1216	O14559
PGINEHPPWAGPQHP	CHERP	596	Q8IWX8
HPPWAGPQHPDFGPP	CHERP	601	Q8IWX8
PPARPHSPLRWPSPT	CROCC2	1336	H7BZ55
RGPHPPWTEVRGPPP	FAM193B	641	Q96PV7
HPLLPGSRWLPPPLA	LINC00322	96	Q6ZN03
PILPPTAAERHNPWP	FNIP2	581	Q9P278
PPGPCHKLPPAPAWH	AXIN1	431	O15169
PPDGALSHPQAPRWP	DUX4L9	246	Q6RFH8
LSHPQAPRWPPHPGK	DUX4L9	251	Q6RFH8
LGPPPHVAAGWSPDP	DUSP15	201	Q9H1R2
PPPQPRAPGKWVHGS	GARRE1	746	O15063
PPDGALSHPQAPRWP	DUX4L7	246	P0CJ90
LSHPQAPRWPPHPGK	DUX4L7	251	P0CJ90
LLDGPSPPAPLHWPG	FOXL1	196	Q12952
PHWLPGPLHSPGLPL	CBLN3	6	Q6UW01
TLAPLPHPAAPWPLG	DVL1	521	O14640
TLAPLPHPAAPWPLG	DVL1P1	496	P54792
PPDGALSHPQAPRWP	DUX4L5	246	P0CJ88
LSHPQAPRWPPHPGK	DUX4L5	251	P0CJ88
HPQDGRSAWPPPGPI	SCAP	671	Q12770
RSAWPPPGPIPAGHW	SCAP	676	Q12770
WPGRPQSHPPAPPVQ	PRRT3	396	Q5FWE3
PGPQHAPFWSTVPPP	PPRC1	986	Q5VV67
PFPFHPLQPWKPHPL	MAP3K14	266	Q99558
WFSGPHPPPGDLLPR	MN1	631	Q10571
GEEHQLPPPPPGSFW	MAP3K5	41	Q99683
WSHGLPLPPPPPAAQ	NUTM2F	151	A1L443
WSHGLPLPPPPPAAQ	NUTM2G	151	Q5VZR2
WRPPGPHLPPAPGQP	METTL24	51	Q5JXM2
AVPPGPHWLLGTPLP	GRIN3B	251	O60391
PWGPPAGPLHVQLFP	GDF6	176	Q6KF10
WGLPHAPPSPGPLSP	SZT2	1351	Q5T011
PAVWPPPVPAEHRAP	KATNAL1	96	Q9BW62
GPPLPHQPPPAWRHT	SH2D2A	351	Q9NP31
HWPLPHIPWPGPNRV	MAB21L1	186	Q13394
HSPEWPPADALPLPP	TAF1C	776	Q15572
PLPPPHRGPAGNWGP	PRRC2A	411	P48634
RGPCHPMHNWPRPIP	PRR32	216	B1ATL7
HPRPASGPPRLGPWE	KDF1	6	Q8NAX2
GLAGHPLKPLPWPVP	SOWAHB	476	A6NEL2
PWPPFPGVFLHPRPL	B4GALNT4	546	Q76KP1
QPQPWPGLTPPGWHT	CMTM5	116	Q96DZ9
LEPGRPPPTGPEHKW	TNRC18	496	O15417
GPPPRHWASPPHKRA	RBMXL3	151	Q8N7X1
GIPSWNDHGPLKPPP	SPATA31A1	901	Q5TZJ5
WASSPPPPHRLPPNP	SPEM2	276	Q0P670
GPHDWLSLPVPPGPS	IGSF9B	551	Q9UPX0
PPLHAWQAGTPPPPS	TICAM1	631	Q8IUC6
LLGVPWQPPGPPIQH	TLE7	46	A0A1W2PR48
PMVPWPPVVHLPGQP	PHF3	1851	Q92576
PQPPPRKLHGWAPGP	PRRC2B	451	Q5JSZ5
LPPPHLPARPPGGWS	nan	41	Q8N9P0
RAPPPPSNPHWRGAL	ZNF843	316	Q8N446
PLPLPIPWGPRHSQD	ZNF831	951	Q5JPB2
PWPGHNLHQTGPAPP	VGLL3	186	A8MV65
HPLQIPAPSWPIHGP	TUT4	1496	Q5TAX3
GAPPRPWTPLQPGLH	WWC2-AS2	171	Q96NR7
PWTPLQPGLHHRPPS	WWC2-AS2	176	Q96NR7
PPLGPHPLMPANPWG	ZC3H18	266	Q86VM9
PGGPQHHQPQPPLWT	UBALD1	131	Q8TB05
PAAPARHGSLPLPWP	ZNF783	526	Q6ZMS7
PPDGALSHPQAPRWP	DUX4L2	246	P0CJ85
LSHPQAPRWPPHPGK	DUX4L2	251	P0CJ85
RVQTPPWHPPGAPSP	MYRF	316	Q9Y2G1
PWHPPGAPSPGLLQD	MYRF	321	Q9Y2G1