Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	TUT4 SETX AGO2 RBBP8 SMARCAD1 INO80 ERI2 GTDC1 DICER1 BPTF MLH3 POLR1B PRIMPOL	1.05e-04	645	117	13	GO:0140640
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	SETX RBBP8 SMARCAD1 INO80 DICER1 BPTF MLH3 PRIMPOL	1.57e-04	262	117	8	GO:0140097
GeneOntologyCellularComponent	NLRP1 inflammasome complex	CASP4 CASP5 CASP12	3.38e-06	6	117	3	GO:0072558
GeneOntologyCellularComponent	non-canonical inflammasome complex	CASP4 CASP5	3.11e-05	2	117	2	GO:0160074
GeneOntologyCellularComponent	canonical inflammasome complex	CASP4 CASP5 CASP12	1.31e-04	18	117	3	GO:0061702
GeneOntologyCellularComponent	PR-DUB complex	ASXL3 ASXL2	1.85e-04	4	117	2	GO:0035517
GeneOntologyCellularComponent	postsynapse	AGO2 ATR VEZT MYO9A APBA2 LRRTM3 CBLB DICER1 ASAP1 NEDD4 AKAP9 GPR158 MTMR2 MACF1 AGAP2	5.59e-04	1018	117	15	GO:0098794
GeneOntologyCellularComponent	stereocilia coupling link	VEZT DIAPH3	8.51e-04	8	117	2	GO:0002139
MousePheno	abnormal meiosis	SETX ATR DICER1 NEDD4 MLH3 AKAP9 CCNB3 NXF5 MYBL1 BRWD1	4.02e-06	241	92	10	MP:0001930
MousePheno	abnormal cell cycle	SETX ATR RBBP8 DICER1 NEDD4 FANCC MLH3 AKAP9 CCNB3 NXF5 DIAPH3 PRIMPOL MYBL1 BRWD1	7.13e-06	520	92	14	MP:0003077
MousePheno	abnormal sex determination	SETX ZNF148 ATR ZFPM2 NEDD4 FANCC EBF2 NHSL1 FANCB SMYD4 LRGUK MLH3 AKAP9 WDR11 NXF5 TNFAIP3 GOLGA3 MYBL1 BRWD1	1.00e-05	945	92	19	MP:0002210
MousePheno	abnormal primary sex determination	SETX ZNF148 ATR ZFPM2 NEDD4 FANCC EBF2 NHSL1 FANCB SMYD4 LRGUK MLH3 AKAP9 WDR11 NXF5 GOLGA3 MYBL1 BRWD1	1.95e-05	901	92	18	MP:0002211
MousePheno	absent distal visceral endoderm	INO80 BPTF	4.28e-05	2	92	2	MP:0012161
MousePheno	small gonad	SETX ZNF148 ATR NEDD4 FANCC EBF2 NHSL1 FANCB SMYD4 LRGUK MLH3 AKAP9 WDR11 NXF5 GOLGA3 MYBL1 BRWD1	5.65e-05	885	92	17	MP:0001116
MousePheno	small testis	SETX ZNF148 ATR FANCC EBF2 NHSL1 FANCB SMYD4 LRGUK MLH3 AKAP9 WDR11 NXF5 GOLGA3 MYBL1 BRWD1	8.38e-05	823	92	16	MP:0001147
MousePheno	abnormal gametogenesis	SETX ATR SMARCAD1 DZIP1 DICER1 NEDD4 FANCC FANCB LRGUK MLH3 AKAP9 WDR11 CCNB3 NXF5 MTMR2 GOLGA3 MYBL1 BRWD1	1.81e-04	1070	92	18	MP:0001929
MousePheno	abnormal circulating interleukin-18 level	CASP4 CASP5 CASP12	2.10e-04	18	92	3	MP:0008634
MousePheno	abnormal oogenesis	ATR SMARCAD1 DICER1 FANCC MLH3 CCNB3 BRWD1	2.23e-04	186	92	7	MP:0001931
MousePheno	abnormal female meiosis	ATR DICER1 MLH3 CCNB3 BRWD1	2.27e-04	84	92	5	MP:0005168
MousePheno	abnormal distal visceral endoderm morphology	INO80 BPTF	2.55e-04	4	92	2	MP:0010126
MousePheno	abnormal testis size	SETX ZNF148 ATR FANCC EBF2 NHSL1 FANCB SMYD4 LRGUK MLH3 AKAP9 WDR11 NXF5 GOLGA3 MYBL1 BRWD1	2.84e-04	915	92	16	MP:0004849
Domain	Pept_C14A_CASP1-typ	CASP4 CASP5 CASP12	8.66e-06	7	119	3	IPR017350
Domain	Caspase_his_AS	CASP4 CASP5 CASP12	5.32e-05	12	119	3	IPR016129
Domain	CASPASE_CYS	CASP4 CASP5 CASP12	5.32e-05	12	119	3	PS01122
Domain	Pept_C14_p10	CASP4 CASP5 CASP12	5.32e-05	12	119	3	IPR002138
Domain	Caspase_cys_AS	CASP4 CASP5 CASP12	5.32e-05	12	119	3	IPR033139
Domain	CASPASE_P10	CASP4 CASP5 CASP12	5.32e-05	12	119	3	PS50207
Domain	CASc	CASP4 CASP5 CASP12	6.88e-05	13	119	3	SM00115
Domain	Pept_C14A	CASP4 CASP5 CASP12	6.88e-05	13	119	3	IPR015917
Domain	-	CASP4 CASP5 CASP12	8.72e-05	14	119	3	3.40.50.1460
Domain	Pept_C14_p20	CASP4 CASP5 CASP12	8.72e-05	14	119	3	IPR001309
Domain	Caspase-like_dom	CASP4 CASP5 CASP12	8.72e-05	14	119	3	IPR029030
Domain	CASPASE_P20	CASP4 CASP5 CASP12	8.72e-05	14	119	3	PS50208
Domain	Adaptor_Cbl_EF_hand-like	CBL CBLB	1.20e-04	3	119	2	IPR014741
Domain	HARE-HTH	ASXL3 ASXL2	1.20e-04	3	119	2	PF05066
Domain	Adaptor_Cbl_SH2-like	CBL CBLB	1.20e-04	3	119	2	IPR014742
Domain	ASXH	ASXL3 ASXL2	1.20e-04	3	119	2	PF13919
Domain	PHD_3	ASXL3 ASXL2	1.20e-04	3	119	2	PF13922
Domain	ASX-like_PHD	ASXL3 ASXL2	1.20e-04	3	119	2	IPR026905
Domain	ASXH	ASXL3 ASXL2	1.20e-04	3	119	2	IPR028020
Domain	Adaptor_Cbl	CBL CBLB	1.20e-04	3	119	2	IPR024162
Domain	Cbl_PTB	CBL CBLB	1.20e-04	3	119	2	IPR024159
Domain	Cbl_N2	CBL CBLB	1.20e-04	3	119	2	PF02761
Domain	Cbl_N3	CBL CBLB	1.20e-04	3	119	2	PF02762
Domain	ASX/ASX-like	ASXL3 ASXL2	1.20e-04	3	119	2	IPR024811
Domain	Cbl_N	CBL CBLB	1.20e-04	3	119	2	PF02262
Domain	HB1/Asxl_HTH	ASXL3 ASXL2	1.20e-04	3	119	2	IPR007759
Domain	Adaptor_Cbl_N_hlx	CBL CBLB	1.20e-04	3	119	2	IPR003153
Domain	CBL_PTB	CBL CBLB	1.20e-04	3	119	2	PS51506
Domain	-	CBL CBLB	1.20e-04	3	119	2	1.20.930.20
Domain	CARD	CASP4 CASP5 CASP12	7.35e-04	28	119	3	PF00619
Domain	MACPF_2	MPEG1 C6	8.28e-04	7	119	2	PS51412
Domain	MACPF_1	MPEG1 C6	8.28e-04	7	119	2	PS00279
Domain	CARD	CASP4 CASP5 CASP12	9.95e-04	31	119	3	IPR001315
Domain	CARD	CASP4 CASP5 CASP12	1.20e-03	33	119	3	PS50209
Domain	PAZ	AGO2 DICER1	1.41e-03	9	119	2	PS50821
Domain	PAZ	AGO2 DICER1	1.41e-03	9	119	2	SM00949
Domain	PAZ	AGO2 DICER1	1.41e-03	9	119	2	PF02170
Domain	PAZ_dom	AGO2 DICER1	1.41e-03	9	119	2	IPR003100
Domain	CYCLIN	RBL2 CCNG1 CCNB3	1.81e-03	38	119	3	SM00385
Domain	-	RBL2 CCNG1 CCNB3	2.10e-03	40	119	3	1.10.472.10
Domain	CASPASE_HIS	CASP4 CASP5	2.13e-03	11	119	2	PS01121
Domain	MACPF	MPEG1 C6	2.13e-03	11	119	2	PF01823
Domain	MACPF	MPEG1 C6	2.55e-03	12	119	2	IPR020864
Domain	MACPF	MPEG1 C6	2.55e-03	12	119	2	SM00457
Domain	Ank_2	FEM1C ANKRD27 ASAP1 ANKAR ANKRD7 AGAP2	2.56e-03	215	119	6	PF12796
Domain	Cyclin-like	RBL2 CCNG1 CCNB3	2.58e-03	43	119	3	IPR013763
Domain	CARD	CASP4 CASP5	4.56e-03	16	119	2	SM00114
Domain	-	FEM1C ANKRD27 ASAP1 ANKAR ANKRD7 AGAP2	5.14e-03	248	119	6	1.25.40.20
Domain	ANK	FEM1C ANKRD27 ASAP1 ANKAR ANKRD7 AGAP2	5.45e-03	251	119	6	SM00248
Domain	ANK_REPEAT	FEM1C ANKRD27 ASAP1 ANKAR ANKRD7 AGAP2	5.66e-03	253	119	6	PS50088
Domain	Ankyrin_rpt-contain_dom	FEM1C ANKRD27 ASAP1 ANKAR ANKRD7 AGAP2	5.77e-03	254	119	6	IPR020683
Domain	ANK_REP_REGION	FEM1C ANKRD27 ASAP1 ANKAR ANKRD7 AGAP2	5.77e-03	254	119	6	PS50297
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PITPNM2 SETX AGO2 SANBR DZIP1 INO80 ERI2 FEM1C MELK PREPL DICER1 ANKRD27 STOX2 AKAP11 CEP126	5.46e-10	529	121	15	14621295
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SETX MYO9A STXBP4 DZIP1 CBL TTK MELK ANKRD27 NEDD4 NHSL1 STOX2 OPTN AKAP9 CCDC138 MACF1 AKAP11 MPHOSPH9 TNFAIP3	1.20e-09	861	121	18	36931259
Pubmed	Unpackaging the genetics of mammalian fertility: strategies to identify the "reproductive genome".	SETX AKAP9 GOLGA3 MYBL1 BRWD1	1.99e-09	16	121	5	29878059
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZSWIM8 TUT4 AGO2 ZNF148 VEZT APBA2 SMARCAD1 INO80 DICER1 NSRP1 BPTF MLH3 RNH1 CCNB3 SMARCC1 MACF1 TAF2 BRWD1	6.43e-08	1116	121	18	31753913
Pubmed	Comparative study of apoptosis-related gene loci in human, mouse and rat genomes.	CASP4 CASP5 CASP12	1.64e-07	4	121	3	15880263
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TBC1D15 ZNF148 VEZT DYNC2H1 STXBP4 SMARCAD1 DZIP1 TTK PREPL DICER1 NSRP1 AKAP9 WDR11 CCDC138 MACF1 AKAP11 WDR41 DIAPH3 GOLGA3 HERC5	2.10e-07	1487	121	20	33957083
Pubmed	Regulation of LFA-1-dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteins.	CBL CBLB ITGB2	4.09e-07	5	121	3	18239087
Pubmed	CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery.	CBL CBLB ASAP1	1.42e-06	7	121	3	17255943
Pubmed	Characterization of seven murine caspase family members.	CASP4 CASP5 CASP12	2.27e-06	8	121	3	9038361
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	DYNC2H1 APBA2 FEM1C MELK PREPL DICER1 LRR1 OPTN RNH1 POLR1B ZNF770 ASXL2 MPHOSPH9 TNFAIP3 DCAF4	2.30e-06	1005	121	15	19615732
Pubmed	Prodomains--adaptors--oligomerization: the pursuit of caspase activation in apoptosis.	CASP4 CASP5 CASP12	3.40e-06	9	121	3	10087912
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	ZSWIM8 TUT4 MYO9A SANBR INO80 TTK NSRP1 NEDD4 TAX1BP1 ZNF506 POLR1B MPHOSPH9 TNFAIP3 BRWD1	4.37e-06	925	121	14	28986522
Pubmed	Identification of polyubiquitin binding proteins involved in NF-kappaB signaling using protein arrays.	CBLB OPTN TAX1BP1 TNFAIP3	4.65e-06	32	121	4	19285159
Pubmed	Stromal-cell-derived factor-1/CXCL12-induced chemotaxis of a T cell line involves intracellular signaling through Cbl and Cbl-b and their regulation by Src kinases and CD45.	CBL CBLB CXCL12	4.84e-06	10	121	3	16503409
Pubmed	Divinations and surprises: genetic analysis of caspase function in mice.	CASP4 CASP5 CASP12	4.84e-06	10	121	3	10739653
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	TUT4 RBL2 CASP5 ERI2 PKHD1L1 THAP2 CHIC2 MTMR2 CKAP2L TNFAIP3 CEP126 KDM6A	5.21e-06	686	121	12	29987050
Pubmed	Sequential ubiquitination of NLRP3 by RNF125 and Cbl-b limits inflammasome activation and endotoxemia.	CASP4 CASP5 CBLB	6.64e-06	11	121	3	31999304
Pubmed	Functional proteomics mapping of a human signaling pathway.	CBLB ANKRD27 NEDD4 THAP2 OPTN TAX1BP1 MACF1 ASXL2 TNFAIP3 DIAPH3 KDM6A	7.36e-06	591	121	11	15231748
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	MYO9A DICER1 NHSL1 CCDC138 MACF1 AKAP11 GOLGA3	9.05e-06	209	121	7	36779422
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ZSWIM8 TRAF3IP1 RBL2 MCF2L2 APBA2 SMARCAD1 DZIP1 PREPL ZNF181 ZNF334 MTMR2 MACF1 KDM6A GOLGA3 AGAP2 BRWD1	1.03e-05	1285	121	16	35914814
Pubmed	Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors.	CBL CBLB NEDD4	1.15e-05	13	121	3	12218189
Pubmed	Revisiting caspase-11 function in host defense.	CASP4 CASP5	1.20e-05	2	121	2	23870309
Pubmed	Alteration in the differentiation-related molecular expression in the subventricular zone in a mouse model of Parkinson's disease.	CASP4 CASP5	1.20e-05	2	121	2	17963913
Pubmed	Caspase-11 mediates oligodendrocyte cell death and pathogenesis of autoimmune-mediated demyelination.	CASP4 CASP5	1.20e-05	2	121	2	11136825
Pubmed	The involvement of caspase-11 in TPEN-induced apoptosis.	CASP4 CASP5	1.20e-05	2	121	2	18474237
Pubmed	A locus on chromosome 9 is associated with differential response of 129S1/SvImJ and FVB/NJ strains of mice to systemic LPS.	CASP4 CASP5	1.20e-05	2	121	2	21720866
Pubmed	Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis.	CASP4 CASP12	1.20e-05	2	121	2	15975932
Pubmed	The human-specific CASP4 gene product contributes to Alzheimer-related synaptic and behavioural deficits.	CASP4 CASP5	1.20e-05	2	121	2	27516385
Pubmed	Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy.	CBL CBLB	1.20e-05	2	121	2	25871390
Pubmed	Caspase-11 signaling promotes damage to hippocampal CA3 to enhance cognitive dysfunction in infection.	CASP4 CASP5	1.20e-05	2	121	2	39179968
Pubmed	MicroRNA-Independent Modulation of DICER1 Expression by hAgo2.	AGO2 DICER1	1.20e-05	2	121	2	32778571
Pubmed	Caspase-11-mediated tubular epithelial pyroptosis underlies contrast-induced acute kidney injury.	CASP4 CASP5	1.20e-05	2	121	2	30250284
Pubmed	Caspase-11: the driving factor for noncanonical inflammasomes.	CASP4 CASP5	1.20e-05	2	121	2	24037676
Pubmed	Induction of caspase-11 by aspartyl proteinases of Candida albicans and implication in promoting inflammatory response.	CASP4 CASP5	1.20e-05	2	121	2	25712931
Pubmed	Decreased AGO2 and DCR1 in PBMCs from War Veterans with PTSD leads to diminished miRNA resulting in elevated inflammation.	AGO2 DICER1	1.20e-05	2	121	2	28850112
Pubmed	Inflammatory caspases are innate immune receptors for intracellular LPS.	CASP4 CASP5	1.20e-05	2	121	2	25119034
Pubmed	Cbl-b is a negative regulator of inflammatory cytokines produced by IgE-activated mast cells.	CBL CBLB	1.20e-05	2	121	2	17056522
Pubmed	Altered expression of caspases-4 and -5 during inflammatory bowel disease and colorectal cancer: Diagnostic and therapeutic potential.	CASP4 CASP5	1.20e-05	2	121	2	25943872
Pubmed	E3 ubiquitin ligase Cbl-b regulates Pten via Nedd4 in T cells independently of its ubiquitin ligase activity.	CBLB NEDD4	1.20e-05	2	121	2	22763434
Pubmed	Caspase-11 activation in response to bacterial secretion systems that access the host cytosol.	CASP4 CASP5	1.20e-05	2	121	2	23762026
Pubmed	Association of a new c-Cbl related protein with the very first stages of apoptosis induction.	CBL CBLB	1.20e-05	2	121	2	12102152
Pubmed	Cbl and Cbl-b control the germinal center reaction by facilitating naive B cell antigen processing.	CBL CBLB	1.20e-05	2	121	2	32584413
Pubmed	Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE.	CASP4 CASP5	1.20e-05	2	121	2	8702803
Pubmed	Mammalian caspases: structure, activation, substrates, and functions during apoptosis.	CASP4 CASP5	1.20e-05	2	121	2	10872455
Pubmed	WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation.	CBLB NEDD4	1.20e-05	2	121	2	12907674
Pubmed	Genome-wide identification of targets and function of individual MicroRNAs in mouse embryonic stem cells.	AGO2 DICER1	1.20e-05	2	121	2	20975942
Pubmed	A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor.	RBBP8 RBL2	1.20e-05	2	121	2	10449734
Pubmed	Down-regulation of Dicer and Ago2 is associated with cell proliferation and apoptosis in prostate cancer.	AGO2 DICER1	1.20e-05	2	121	2	25135428
Pubmed	CtIP Mutations Cause Seckel and Jawad Syndromes.	ATR RBBP8	1.20e-05	2	121	2	21998596
Pubmed	The role of E3 ubiquitin ligase Cbl proteins in β-elemene reversing multi-drug resistance of human gastric adenocarcinoma cells.	CBL CBLB	1.20e-05	2	121	2	23665906
Pubmed	CASP4/caspase-11 promotes autophagosome formation in response to bacterial infection.	CASP4 CASP5	1.20e-05	2	121	2	30165781
Pubmed	Caspase-11 promotes allergic airway inflammation.	CASP4 CASP5	1.20e-05	2	121	2	32103022
Pubmed	Lipid A Variants Activate Human TLR4 and the Noncanonical Inflammasome Differently and Require the Core Oligosaccharide for Inflammasome Activation.	CASP4 CASP5	1.20e-05	2	121	2	35862709
Pubmed	c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation.	CBL CBLB	1.20e-05	2	121	2	12415267
Pubmed	Mechanical Ventilation Exacerbates Poly (I:C) Induced Acute Lung Injury: Central Role for Caspase-11 and Gut-Lung Axis.	CASP4 CASP5	1.20e-05	2	121	2	34349759
Pubmed	Inhibition of caspase-11 under inflammatory conditions suppresses chondrogenic differentiation.	CASP4 CASP5	1.20e-05	2	121	2	38875922
Pubmed	Essential role of caspase-11 in activation-induced cell death of rat astrocytes.	CASP4 CASP5	1.20e-05	2	121	2	11902113
Pubmed	Caspases determine the vulnerability of oligodendrocytes in the ischemic brain.	CASP4 CASP5	1.20e-05	2	121	2	10974017
Pubmed	Ago2 and GW182 expression in mouse preimplantation embryos: a link between microRNA biogenesis and GW182 protein synthesis.	AGO2 DICER1	1.20e-05	2	121	2	20353723
Pubmed	Caspase-11-Mediated Cell Death Contributes to the Pathogenesis of Imiquimod-Induced Psoriasis.	CASP4 CASP5	1.20e-05	2	121	2	31173764
Pubmed	Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.	CASP4 CASP5	1.20e-05	2	121	2	14985426
Pubmed	Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11.	CASP4 CASP5	1.20e-05	2	121	2	29339744
Pubmed	The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases.	TAX1BP1 TNFAIP3	1.20e-05	2	121	2	10435631
Pubmed	Caspase-11 Contributes to Oviduct Pathology during Genital Chlamydia Infection in Mice.	CASP4 CASP5	1.20e-05	2	121	2	31160363
Pubmed	Caspase-11 attenuates gastrointestinal inflammation and experimental colitis pathogenesis.	CASP4 CASP5	1.20e-05	2	121	2	25414099
Pubmed	mRNA-Seq whole-transcriptome analysis of a single cell.	AGO2 DICER1	1.20e-05	2	121	2	19349980
Pubmed	Caspase-11 Mediates Pyroptosis of Tubular Epithelial Cells and Septic Acute Kidney Injury.	CASP4 CASP5	1.20e-05	2	121	2	31230050
Pubmed	The RNA-RNA base pairing potential of human Dicer and Ago2 proteins.	AGO2 DICER1	1.20e-05	2	121	2	31655860
Pubmed	Caspase-11-mediated enteric neuronal pyroptosis underlies Western diet-induced colonic dysmotility.	CASP4 CASP5	1.20e-05	2	121	2	32484462
Pubmed	Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation.	CASP4 CASP5	1.20e-05	2	121	2	30135078
Pubmed	Inappropriate use of antibiotics exacerbates inflammation through OMV-induced pyroptosis in MDR Klebsiella pneumoniae infection.	CASP4 CASP5	1.20e-05	2	121	2	34551309
Pubmed	Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS.	CASP4 CASP5	1.20e-05	2	121	2	38231198
Pubmed	Shigella evades pyroptosis by arginine ADP-riboxanation of caspase-11.	CASP4 CASP5	1.20e-05	2	121	2	34671164
Pubmed	Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes.	CASP4 CASP5	1.20e-05	2	121	2	26508369
Pubmed	Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases.	CASP4 CASP5	1.20e-05	2	121	2	7797592
Pubmed	Stearoyl Lysophosphatidylcholine Inhibits Endotoxin-Induced Caspase-11 Activation.	CASP4 CASP5	1.20e-05	2	121	2	28991049
Pubmed	Caspase-4 dimerisation and D289 auto-processing elicit an interleukin-1β-converting enzyme.	CASP4 CASP5	1.20e-05	2	121	2	37558421
Pubmed	Casp11 Deficiency Alters Subgingival Microbiota and Attenuates Periodontitis.	CASP4 CASP5	1.20e-05	2	121	2	38197150
Pubmed	Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1.	CASP4 CASP5	1.20e-05	2	121	2	22895188
Pubmed	A novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells.	CBL CBLB	1.20e-05	2	121	2	27276677
Pubmed	Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia.	CBL CBLB	1.20e-05	2	121	2	17475912
Pubmed	Protective role for caspase-11 during acute experimental murine colitis.	CASP4 CASP5	1.20e-05	2	121	2	25548224
Pubmed	Essential Role for endogenous siRNAs during meiosis in mouse oocytes.	AGO2 DICER1	1.20e-05	2	121	2	25695507
Pubmed	Cytoplasmic innate immune sensing by the caspase-4 non-canonical inflammasome promotes cellular senescence.	CASP4 CASP5	1.20e-05	2	121	2	34916628
Pubmed	Fasudil, a clinically safe ROCK inhibitor, decreases disease burden in a Cbl/Cbl-b deficiency-driven murine model of myeloproliferative disorders.	CBL CBLB	1.20e-05	2	121	2	26177294
Pubmed	The Brucella effector protein TcpB induces degradation of inflammatory caspases and thereby subverts non-canonical inflammasome activation in macrophages.	CASP4 CASP5	1.20e-05	2	121	2	29061850
Pubmed	Dissociation between neurodegeneration and caspase-11-mediated activation of caspase-1 and caspase-3 in a mouse model of amyotrophic lateral sclerosis.	CASP4 CASP5	1.20e-05	2	121	2	12843244
Pubmed	Caspase-11 Plays a Protective Role in Pulmonary Acinetobacter baumannii Infection.	CASP4 CASP5	1.20e-05	2	121	2	28760936
Pubmed	Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomy.	CBL CBLB	1.20e-05	2	121	2	24994594
Pubmed	Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation.	CASP4 CASP5	1.20e-05	2	121	2	27156449
Pubmed	Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages.	CASP4 CASP5	1.20e-05	2	121	2	36776889
Pubmed	Caspase-11-Mediated Hepatocytic Pyroptosis Promotes the Progression of Nonalcoholic Steatohepatitis.	CASP4 CASP5	1.20e-05	2	121	2	33894425
Pubmed	Interferon-induced guanylate-binding proteins promote cytosolic lipopolysaccharide detection by caspase-11.	CASP4 CASP5	1.20e-05	2	121	2	25347553
Pubmed	Activation of DSB processing requires phosphorylation of CtIP by ATR.	ATR RBBP8	1.20e-05	2	121	2	23273981
Pubmed	Role of caspase-11 non-canonical inflammasomes in retinal ischemia/reperfusion injury.	CASP4 CASP5	1.20e-05	2	121	2	39333859
Pubmed	cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis.	CASP4 CASP5	1.20e-05	2	121	2	31131320
Pubmed	Cutting Edge: Caspase-11 Limits the Response of CD8+ T Cells to Low-Abundance and Low-Affinity Antigens.	CASP4 CASP5	1.20e-05	2	121	2	25980012
Pubmed	The Fanconi anemia family of genes and its correlation with breast cancer susceptibility and breast cancer features.	ATR FANCC FANCB	1.81e-05	15	121	3	19536649
Pubmed	Expression of caspase family and muscle- and apoptosis-specific genes during skeletal myogenesis in mouse embryo.	CASP4 CASP5 CASP12	1.81e-05	15	121	3	19801895
Pubmed	Expression of caspase and BCL-2 apoptotic family members in mouse preimplantation embryos.	CASP4 CASP5 CASP12	1.81e-05	15	121	3	10377054
Interaction	ELF4 interactions	ZNF148 CASP4 INO80 BPTF ASXL2 TAF2 KDM6A	6.05e-06	115	121	7	int:ELF4
Interaction	PTK2B interactions	PITPNM2 CBL CBLB ITGB2 ASAP1 NEDD4 AGAP2	7.59e-06	119	121	7	int:PTK2B
Interaction	YWHAZ interactions	AGO2 COL6A6 MYO9A DZIP1 CBL MELK ITGB2 ANKRD27 NEDD4 NHSL1 STOX2 OPTN AKAP9 ASXL3 TAX1BP1 MACF1 AKAP11 ASXL2 MPHOSPH9 TNFAIP3 CEP126 GOLGA3	1.11e-05	1319	121	22	int:YWHAZ
Interaction	GOLGA1 interactions	PDXDC1 DICER1 WDR11 CCDC138 MACF1 MPHOSPH9 DIAPH3 GOLGA3	1.49e-05	183	121	8	int:GOLGA1
Cytoband	Ensembl 112 genes in cytogenetic band chr11q22	DYNC2H1 CASP4 CASP5 CASP12 CEP126	1.00e-05	107	121	5	chr11q22
Cytoband	11q22.2-q22.3	CASP4 CASP5	2.06e-05	3	121	2	11q22.2-q22.3
Cytoband	2q13	FBLN7 CKAP2L POLR1B	7.90e-04	68	121	3	2q13
Cytoband	12q21.1	TBC1D15 THAP2	8.07e-04	16	121	2	12q21.1
Cytoband	8q23	PKHD1L1 ZFPM2	1.03e-03	18	121	2	8q23
GeneFamily	Caspases\|Caspase recruitment domain containing	CASP4 CASP5 CASP12	1.90e-05	13	75	3	468
GeneFamily	WD repeat domain containing\|Caspase recruitment domain containing\|Apoptosome	CASP4 CASP5 CASP12	2.57e-04	30	75	3	959
GeneFamily	Ankyrin repeat domain containing	FEM1C ANKRD27 ASAP1 ANKAR ANKRD7 AGAP2	5.03e-04	242	75	6	403
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	ASAP1 AGAP2	2.22e-03	17	75	2	1291
GeneFamily	WD repeat domain containing\|DDB1 and CUL4 associated factors	DCAF4 BRWD1	2.49e-03	18	75	2	498
GeneFamily	Ring finger proteins\|Fanconi anemia complementation groups\|Protein phosphatase 1 regulatory subunits\|BRCA1 A complex\|BRCA1 B complex\|BRCA1 C complex	FANCC FANCB	3.07e-03	20	75	2	548
GeneFamily	Neuroblastoma breakpoint family	NBPF8 NBPF11	4.06e-03	23	75	2	662
GeneFamily	Cyclins	CCNG1 CCNB3	5.99e-03	28	75	2	473
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	AKAP9 AKAP11	6.41e-03	29	75	2	396
GeneFamily	ArfGAPs	ASAP1 AGAP2	8.25e-03	33	75	2	395
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF148 ZNF181 ZFPM2 ZNF677 ZNF334 ZNF506 ZNF770 ZNF614	9.64e-03	718	75	8	28
GeneFamily	Complement system\|Sushi domain containing	ITGB2 C6	9.76e-03	36	75	2	492
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	TCEA1 TUT4 SETX ZNF148 ATR MYO9A RBBP8 SMARCAD1 DZIP1 TTK NSRP1 BPTF STOX2 OPTN WDR11 TAX1BP1 AKAP11 DIAPH3 MYBL1	1.84e-10	656	121	19	M18979
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	TUT4 SETX AGO2 ZNF148 ATR CBLB TTK MELK DICER1 NEDD4 BPTF AKAP9 MACF1 AKAP11 MPHOSPH9 CXCL12 MYBL1	4.29e-07	856	121	17	M4500
Coexpression	ZHANG_BREAST_CANCER_PROGENITORS_UP	TCEA1 SETX ZNF148 ATR RBBP8 ERI2 MELK AKAP9 WDR11 TAX1BP1 ZNF770 TAF2	8.40e-07	434	121	12	M15150
Coexpression	ZHANG_BREAST_CANCER_PROGENITORS_UP	TCEA1 SETX ZNF148 ATR RBBP8 ERI2 MELK AKAP9 WDR11 TAX1BP1 ZNF770 TAF2	1.17e-06	448	121	12	MM1044
Coexpression	DE_YY1_TARGETS_DN	RBBP8 RBL2 TTK CCNG1 MACF1 MPHOSPH9	4.69e-06	93	121	6	M3278
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	TUT4 COL6A6 APBA2 PREPL DICER1 ZFPM2 EBF2 STOX2 OPTN AKAP9 GPR158 ASXL3 ANKAR CEP126 GOLGA3 CCDC144A BRWD1	1.33e-05	1106	121	17	M39071
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	TUT4 SETX ZNF148 ATR RBL2 APBA2 CGGBP1 CBL CBLB ITGB2 DICER1 ASAP1 BPTF AKAP9 MACF1 AKAP11 ASXL2 TNFAIP3 MYBL1 BRWD1	1.59e-05	1492	121	20	M40023
Coexpression	DODD_NASOPHARYNGEAL_CARCINOMA_UP	FUT10 AGO2 ATR VEZT RBBP8 SMARCAD1 TTK MELK ASAP1 NEDD4 CCNG1 THAP2 LRR1 POLR1B MPHOSPH9 DIAPH3 ZNF614 PRIMPOL L3MBTL4	2.41e-05	1407	121	19	M14427
Coexpression	GSE27241_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP	CEP76 ERI2 MELK CKAP2L DIAPH3 GOLGA3 MYBL1	3.73e-05	197	121	7	M8226
Coexpression	GSE1460_CORD_VS_ADULT_BLOOD_NAIVE_CD4_TCELL_UP	TUT4 RBBP8 RBL2 TTK SMARCC1 TNFAIP3 PCOLCE	3.73e-05	197	121	7	M3480
Coexpression	ERBB2_UP.V1_DN	ATR RBBP8 ERI2 TTK TAF2 MYBL1 BRWD1	3.73e-05	197	121	7	M2635
Coexpression	GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_UP	TCEA1 SANBR CEP76 CGGBP1 MELK CKAP2L DIAPH3	3.98e-05	199	121	7	M8961
Coexpression	GSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_DN	TUT4 RBL2 CBLB DICER1 CCNG1 MACF1 POLR1B	3.98e-05	199	121	7	M7607
Coexpression	GSE23321_CD8_STEM_CELL_MEMORY_VS_EFFECTOR_MEMORY_CD8_TCELL_DN	TCEA1 TUT4 RBL2 FEM1C RAB33A TAX1BP1 TNFAIP3	3.98e-05	199	121	7	M8430
Coexpression	GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_UP	RBBP8 TTK MELK LRR1 CKAP2L DIAPH3 MYBL1	4.11e-05	200	121	7	M3577
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	TUT4 ZNF148 ATR CBLB MELK NEDD4 BPTF AKAP9 CXCL12 MYBL1	6.25e-05	466	121	10	M13522
Coexpression	KIM_MYCN_AMPLIFICATION_TARGETS_UP	DICER1 FANCC RAB33A MACF1 L3MBTL4	7.25e-05	93	121	5	M18532
Coexpression	GSE12507_PDC_CELL_LINE_VS_IMMATUE_T_CELL_LINE_UP	RBBP8 CEP76 PKHD1L1 FANCC CCNG1 FANCB	7.93e-05	153	121	6	M438
Coexpression	VANTVEER_BREAST_CANCER_ESR1_DN	TTK MELK ITGB2 CHIC2 OPTN MTMR2 TNFAIP3	8.39e-05	224	121	7	M15425
Coexpression	SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP	AGO2 VEZT RBBP8 TTK MELK ASAP1 MPHOSPH9 DIAPH3	8.85e-05	305	121	8	M19875
Coexpression	KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP	TCEA1 AGO2 ATR TTK MELK DICER1 ASAP1 NEDD4 SMYD4 LRR1 CCDC138 CKAP2L SMARCC1 MPHOSPH9 TAF2 PRIMPOL MYBL1	9.12e-05	1290	121	17	M80
Coexpression	DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP	RBBP8 TTK MELK FANCC LRR1 MPHOSPH9 CXCL12 MYBL1	1.31e-04	323	121	8	M2156
Coexpression	FARMER_BREAST_CANCER_APOCRINE_VS_BASAL	RBBP8 FEM1C MELK ANKRD27 NEDD4 OPTN AKAP9 HERC5	1.49e-04	329	121	8	M2631
Coexpression	GSE9601_UNTREATED_VS_NFKB_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_DN	FUT10 VEZT AKAP9 WDR11 WDR41 TAF2	1.61e-04	174	121	6	M6881
Coexpression	GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP	CASP4 TTK OPTN CKAP2L HERC5 MYBL1	1.71e-04	176	121	6	M2981
Coexpression	RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP	ATR DYNC2H1 RBBP8 TTK NEDD4 LRR1 ASXL2 WDR41 DIAPH3 MYBL1 BRWD1	2.01e-04	644	121	11	M10501
Coexpression	ZAK_PBMC_MRKAD5_HIV_1_GAG_POL_NEF_AGE_20_50YO_1DY_DN	FUT10 TUT4 RBL2 APBA2 CBLB PREPL ZNF181 CCNG1 BPTF ZNF506 MACF1 MPHOSPH9 MYBL1 BRWD1	2.44e-04	1012	121	14	M40864
Coexpression	GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP	SANBR ERI2 TTK MELK MPHOSPH9 MYBL1	2.89e-04	194	121	6	M7467
Coexpression	GSE22886_NAIVE_VS_MEMORY_TCELL_UP	ZNF148 CASR HAUS2 AKAP9 POLR1B MPHOSPH9	2.89e-04	194	121	6	M4416
Coexpression	GSE22886_NAIVE_CD8_TCELL_VS_MEMORY_TCELL_UP	GTDC1 CBLB HAUS2 POLR1B MPHOSPH9 MYBL1	2.97e-04	195	121	6	M4405
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_EARLY_STALK_CELL	SANBR APBA2 TTK MELK FANCB LRR1 CKAP2L TNFAIP3 DIAPH3 PHYHIPL	3.06e-04	567	121	10	M45692
Coexpression	GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_DN	DICER1 ANKRD27 ASAP1 WDR11 TNFAIP3 KDM6A	3.22e-04	198	121	6	M3248
Coexpression	GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_UP	RBL2 ITGB2 AKAP9 ZNF506 MACF1 BRWD1	3.22e-04	198	121	6	M5591
Coexpression	GSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_UP	TUT4 MYO9A RBBP8 CBL C6 PRIMPOL	3.31e-04	199	121	6	M6443
Coexpression	GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_DN	SETX ZNF148 CASP4 CGGBP1 OPTN HERC5	3.31e-04	199	121	6	M4635
Coexpression	GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_UP	RBL2 CASP4 CBL ITGB2 TNFAIP3 CXCL12	3.31e-04	199	121	6	M8301
Coexpression	GSE21063_WT_VS_NFATC1_KO_8H_ANTI_IGM_STIM_BCELL_UP	TCEA1 RBBP8 TTK MELK LRR1 DIAPH3	3.31e-04	199	121	6	M8277
Coexpression	GSE32986_GMCSF_AND_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP	PDXDC1 PREPL TAX1BP1 AKAP11 ASXL2 MPHOSPH9	3.31e-04	199	121	6	M8639
Coexpression	ZHENG_FOXP3_TARGETS_IN_THYMUS_UP	TBC1D15 MYO9A FEM1C CBLB ASXL2 TNFAIP3	3.31e-04	199	121	6	M1746
Coexpression	GSE28737_WT_VS_BCL6_HET_MARGINAL_ZONE_BCELL_DN	MYO9A CASP4 CASP12 POLR1B TNFAIP3 DIAPH3	3.40e-04	200	121	6	M9344
Coexpression	GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_DN	FANCB LRR1 AKAP9 ZNF334 WDR11 C6	3.40e-04	200	121	6	M7913
Coexpression	GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_DN	RBBP8 CEP76 GTDC1 MELK NEDD4 RAB33A	3.40e-04	200	121	6	M5303
Coexpression	HALLMARK_COMPLEMENT	CASP4 CASP5 CBLB ZFPM2 TNFAIP3 L3MBTL4	3.40e-04	200	121	6	M5921
Coexpression	GSE23505_IL6_IL1_VS_IL6_IL1_IL23_TREATED_CD4_TCELL_UP	RBL2 CEP76 TTK FANCB CASP12 DIAPH3	3.40e-04	200	121	6	M7869
Coexpression	GSE360_L_DONOVANI_VS_L_MAJOR_MAC_DN	RBBP8 CASR OPTN TAX1BP1 TNFAIP3 CCDC144A	3.40e-04	200	121	6	M5232
Coexpression	GSE42724_NAIVE_VS_MEMORY_BCELL_DN	RBBP8 CASP4 FEM1C NSRP1 FANCC GOLGA3	3.40e-04	200	121	6	M9793
Coexpression	GSE22886_IGA_VS_IGM_MEMORY_BCELL_DN	DYNC2H1 CBL CBLB DICER1 AGAP2 BRWD1	3.40e-04	200	121	6	M4439
Coexpression	ZHENG_FOXP3_TARGETS_IN_THYMUS_UP	TBC1D15 MYO9A FEM1C CBLB ASXL2 TNFAIP3	3.40e-04	200	121	6	MM1033
Coexpression	HE_LIM_SUN_FETAL_LUNG_C7_PROLIFERATING_SCHWANN_CELL	FUT10 RBBP8 CASP4 ERI2 HAUS2 TTK MELK FANCB SMYD4 LRR1 CKAP2L AKAP11 ASXL2 DIAPH3	3.67e-04	1054	121	14	M45798
Coexpression	FOURATI_BLOOD_TWINRIX_AGE_25_83YO_RESPONDERS_VS_POOR_RESPONDERS_0DY_UP	TCEA1 NBPF11 CGGBP1 GTDC1 PKHD1L1 CCNG1 FANCB MTMR2 KDM6A ZNF614	4.02e-04	587	121	10	M40869
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	TUT4 SETX ATR TRAF3IP1 RBBP8 STXBP4 SANBR SMARCAD1 CEP76 ERI2 TTK DICER1 NSRP1 THAP2 BPTF AKAP9 ZNF334 TAX1BP1 CCDC138 ZNF506 CKAP2L SMARCC1 MACF1 ZNF770 CEP126 PHYHIPL MYBL1 BRWD1	2.29e-10	1257	119	28	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	TUT4 SETX ATR TRAF3IP1 RBBP8 STXBP4 SANBR SMARCAD1 CEP76 ERI2 TTK DICER1 NSRP1 THAP2 BPTF AKAP9 ZNF334 TAX1BP1 CCDC138 ZNF506 CKAP2L SMARCC1 MACF1 ZNF770 CEP126 PHYHIPL MYBL1 BRWD1	6.40e-09	1459	119	28	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	facebase_RNAseq_e10.5_MaxArch_2500_K3	TUT4 SETX ATR COL6A6 RBBP8 STXBP4 SANBR SMARCAD1 CEP76 DZIP1 ERI2 TTK THAP2 OPTN AKAP9 ZNF334 TAX1BP1 ZNF506 CKAP2L SMARCC1 ZNF770 ASXL2 CEP126 KDM6A MYBL1	2.26e-08	1252	119	25	facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1	TUT4 SETX STXBP4 SANBR MPEG1 SMARCAD1 CEP76 LRRTM3 ERI2 STOX2 AKAP9 ZNF334 CCDC138 TIGD3 ZNF506 CKAP2L SMARCC1 MACF1 CEP126 PHYHIPL MYBL1 BRWD1	9.34e-08	1060	119	22	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2	TCEA1 TRAF3IP1 INO80 FEM1C DICER1 NSRP1 NEDD4 BPTF ZNF334 TAX1BP1 MACF1 ZNF770 ASXL2 PRIMPOL BRWD1	6.25e-07	564	119	15	Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#4	TUT4 SETX TRAF3IP1 STXBP4 TTK ASXL3 ZNF506 CKAP2L MACF1 MPHOSPH9 CEP126	9.52e-07	298	119	11	Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K4
CoexpressionAtlas	facebase_RNAseq_e10.5_MandArch_2500_K1	TUT4 SETX ATR RBBP8 STXBP4 SMARCAD1 DZIP1 TTK NSRP1 CHIC2 OPTN AKAP9 ZNF334 ASXL3 ZNF506 CKAP2L SMARCC1 MACF1 ZNF770 CEP126 KDM6A BRWD1	1.36e-06	1241	119	22	facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	TUT4 TRAF3IP1 STXBP4 TTK PREPL NSRP1 AKAP9 CKAP2L MACF1 MPHOSPH9	5.72e-06	291	119	10	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	TCEA1 TRAF3IP1 DYNC2H1 SANBR CEP76 FEM1C NSRP1 THAP2 BPTF TAX1BP1 TIGD3 MACF1 ASXL2 PHYHIPL	6.26e-06	595	119	14	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_1000	TUT4 VEZT INO80 CBLB HAUS2 ASAP1 BPTF CHIC2 AKAP9 ASXL2 BRWD1	9.55e-06	379	119	11	gudmap_developingKidney_e15.5_1000_k3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	TUT4 TRAF3IP1 STXBP4 DICER1 NSRP1 AKAP9 CKAP2L MPHOSPH9 KDM6A MYBL1	1.02e-05	311	119	10	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500	TUT4 SETX STXBP4 SANBR MPEG1 SMARCAD1 CEP76 LRRTM3 ERI2 STOX2 AKAP9 ZNF334 CCDC138 TIGD3 ZNF506 CKAP2L SMARCC1 MACF1 CEP126 PHYHIPL MYBL1 BRWD1	1.11e-05	1414	119	22	facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	TRAF3IP1 MYO9A DYNC2H1 STXBP4 SANBR CEP76 GTDC1 PREPL NSRP1 CCNG1 AKAP9 MPHOSPH9 PHYHIPL KDM6A GOLGA3 MYBL1	1.63e-05	831	119	16	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	facebase_RNAseq_e10.5_MandArch_2500	TUT4 SETX ATR RBBP8 STXBP4 SMARCAD1 DZIP1 TTK NSRP1 CHIC2 OPTN AKAP9 ZNF334 ASXL3 ZNF506 CKAP2L SMARCC1 MACF1 ZNF770 CEP126 KDM6A BRWD1	1.98e-05	1468	119	22	facebase_RNAseq_e10.5_MandArch_2500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1	TUT4 TRAF3IP1 MYO9A STXBP4 GTDC1 TTK PREPL NSRP1 CCNG1 AKAP9 CKAP2L MACF1 MPHOSPH9 KDM6A GOLGA3	3.11e-05	780	119	15	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3	TCEA1 TUT4 TRAF3IP1 STXBP4 NSRP1 TAX1BP1 CKAP2L MACF1 ASXL2 PRIMPOL BRWD1	3.20e-05	432	119	11	Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#1_top-relative-expression-ranked_1000	TUT4 AGO2 STXBP4 SMARCAD1 ASXL3 SMARCC1 CXCL12	3.21e-05	159	119	7	gudmap_developingGonad_e11.5_ovary + mesonephros_k1_1000
CoexpressionAtlas	DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#4_top-relative-expression-ranked_1000	CBLB EBF2 ZNF334 ASXL3 MPHOSPH9 MYBL1 BRWD1	3.48e-05	161	119	7	gudmap_developingKidney_e11.5_metaneph mesench_1000_k4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000	TUT4 AGO2 TRAF3IP1 STXBP4 GTDC1 TTK PREPL NSRP1 NHSL1 AKAP9 RNH1 ASXL3 CKAP2L MACF1 AKAP11 MPHOSPH9 CXCL12	3.50e-05	985	119	17	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	TUT4 TRAF3IP1 DYNC2H1 STXBP4 SANBR CEP76 DICER1 NSRP1 EBF2 STOX2 AKAP9 CKAP2L MPHOSPH9 PHYHIPL KDM6A MYBL1 BRWD1	3.69e-05	989	119	17	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5	TCEA1 TRAF3IP1 DYNC2H1 STXBP4 SANBR NSRP1 NEDD4 BPTF AKAP9 TAX1BP1 MACF1 ASXL2 PRIMPOL	5.26e-05	629	119	13	Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000	SETX VEZT HAUS2 ASAP1 STOX2 AKAP9 ASXL3 SMARCC1 ASXL2 PRKG1	6.29e-05	385	119	10	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1	SETX TRAF3IP1 RBBP8 STXBP4 TTK NSRP1 SMYD4 AKAP9 SMARCC1 MPHOSPH9 CEP126	6.71e-05	469	119	11	Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlas	alpha beta T cells, NKT.44-NK1.1-.Th, aGC CD1d tet CD3e, Thymus, avg-2	PITPNM2 CEP76 DZIP1 ERI2 TTK MELK CCNG1 CKAP2L SMARCC1 DIAPH3	8.29e-05	398	119	10	GSM538338_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5	TRAF3IP1 RBBP8 NSRP1 AKAP9 CKAP2L MACF1 MPHOSPH9	8.67e-05	186	119	7	Facebase_RNAseq_e10.5_Mandibular Arch_500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500	TUT4 AGO2 TRAF3IP1 RBBP8 NSRP1 EBF2 AKAP9 ASXL3 CKAP2L MACF1 MPHOSPH9	1.03e-04	492	119	11	Facebase_RNAseq_e10.5_Mandibular Arch_500
CoexpressionAtlas	DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_1000	FBLN7 FUT10 TUT4 SETX ZNF148 DYNC2H1 STXBP4 DZIP1 INO80 LRR1 POLR1B ASXL2 MPHOSPH9 TAF2	1.19e-04	779	119	14	gudmap_developingKidney_e15.5_Cap mesenchyme_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	ATR TTK MELK FANCB LRR1 CCDC138 DIAPH3 PHYHIPL BRWD1	2.01e-04	361	119	9	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	SETX ATR MYO9A RBBP8 TTK MELK FANCB LRR1 CCDC138 AKAP11 DIAPH3 PHYHIPL MYBL1 BRWD1	2.03e-04	820	119	14	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4	TUT4 DYNC2H1 STXBP4 SANBR SMARCAD1 CEP76 ERI2 MELK BPTF STOX2 AKAP9 CCDC138 CKAP2L TAF2 CEP126 PHYHIPL KDM6A MYBL1 BRWD1	2.16e-04	1370	119	19	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000	SETX VEZT INO80 HAUS2 PREPL AKAP9 SMARCC1 ASXL2 PRKG1	2.37e-04	369	119	9	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4	TUT4 STXBP4 ASXL3 ZNF506 CKAP2L	3.14e-04	105	119	5	Facebase_RNAseq_e10.5_Medial Nasal Eminence_500_K4
CoexpressionAtlas	DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#3_top-relative-expression-ranked_500	CBLB ZNF334 ASXL3 GPX6 MPHOSPH9	3.28e-04	106	119	5	gudmap_developingKidney_e11.5_metaneph mesench_500_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#1_top-relative-expression-ranked_500	SETX PREPL ZFPM2 ZNF770 ASXL2 PRKG1 TAF2	3.29e-04	231	119	7	gudmap_developingLowerUrinaryTract_e14.5_ bladder_500_k1
CoexpressionAtlas	DevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#4_top-relative-expression-ranked_1000	AGO2 STXBP4 ASXL3 SMARCC1	4.07e-04	62	119	4	gudmap_developingGonad_e11.5_testes_k4_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000	TCEA1 TUT4 TRAF3IP1 STXBP4 SANBR LRRTM3 NSRP1 EBF2 AKAP9 TAX1BP1 CKAP2L MACF1 ASXL2 PRIMPOL BRWD1	4.23e-04	989	119	15	Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlas	B cells, preB.FrC.BM, CD19+ IgM- CD45R+ CD43+ HSA+, Bone marrow, avg-3	DYNC2H1 ERI2 TTK MELK FANCB LRR1 CKAP2L DIAPH3 MYBL1	5.01e-04	409	119	9	GSM399452_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#1	SETX RBBP8 STXBP4 CEP76 SMYD4 AKAP9 PHYHIPL	6.50e-04	259	119	7	Facebase_RNAseq_e8.5_Floor Plate_1000_K1
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#4_top-relative-expression-ranked_1000	ATR CCDC138 PHYHIPL MYBL1	7.19e-04	72	119	4	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k4_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3	TRAF3IP1 DYNC2H1 SANBR NSRP1 AKAP9 MPHOSPH9	7.53e-04	192	119	6	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4	TRAF3IP1 TTK NSRP1 AKAP9 MACF1 MPHOSPH9	7.53e-04	192	119	6	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K4
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	SETX RBBP8 SANBR SMARCAD1 CEP76 TTK SMARCC1 MPHOSPH9 CEP126 PHYHIPL	8.31e-04	532	119	10	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	DevelopingKidney_e11.5_metaneph mesench_emap-3843_top-relative-expression-ranked_1000	VEZT DYNC2H1 CBLB DICER1 EBF2 ZNF334 ASXL3 GPX6 MPHOSPH9 TNFAIP3 CXCL12 MYBL1 BRWD1	9.66e-04	850	119	13	gudmap_developingKidney_e11.5_metaneph mesench_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	TUT4 SETX ZNF148 TRAF3IP1 STXBP4 DZIP1 TTK ASXL3 ZNF506 CKAP2L MACF1 MPHOSPH9	9.68e-04	744	119	12	Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K4
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	ZNF148 ATR BPTF AKAP9 SMARCC1 POLR1B ZNF770 ASXL2	5.90e-08	193	121	8	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LRRTM3 TTK MELK TIGD3 CKAP2L DIAPH3 MYBL1	5.40e-07	176	121	7	45c6983ab671b0f306e7390320bd84f848e474cc
ToppCell	facs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERI2 MELK FANCC LRR1 CKAP2L DIAPH3 MYBL1	5.61e-07	177	121	7	8a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN7 COL6A6 MELK CKAP2L DIAPH3 ANKRD7 PCOLCE	5.61e-07	177	121	7	4197cf2b1e743230c821f422836fa5991b155a52
ToppCell	facs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERI2 MELK FANCC LRR1 CKAP2L DIAPH3 MYBL1	5.61e-07	177	121	7	e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN7 SANBR MELK FANCB CKAP2L DIAPH3 MYBL1	6.05e-07	179	121	7	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CASR TTK MELK FANCB CKAP2L DIAPH3 MYBL1	6.28e-07	180	121	7	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN7 TTK MELK FANCB CKAP2L DIAPH3 MYBL1	8.11e-07	187	121	7	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A RBBP8 RIPOR3 STOX2 PRKG1 DIAPH3 PHYHIPL	8.40e-07	188	121	7	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	TTK MELK FANCC CCDC138 CKAP2L MPHOSPH9 DIAPH3	1.00e-06	193	121	7	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2H1 SANBR PLEKHG4B LRGUK AKAP9 C6 CEP126	1.15e-06	197	121	7	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	18-Airway-Mesenchymal-Mesenchyme_RSPO2+\|Airway / Age, Tissue, Lineage and Cell class	TTK MELK CKAP2L MACF1 DIAPH3 CXCL12 HERC5	1.23e-06	199	121	7	7ac35e8f45dcdc702422dabd8f3e4d03e2bf61af
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Proliferating-Cycling_Progenitors\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	FBLN7 TTK MELK LRR1 CKAP2L DIAPH3 MYBL1	1.23e-06	199	121	7	a99516a5760f49a69b0fe45a9b2316e393252966
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FBLN7 TTK MELK FANCB CKAP2L DIAPH3 MYBL1	1.23e-06	199	121	7	1d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PITPNM2 TUT4 SETX NEDD4 BPTF MACF1 BRWD1	1.27e-06	200	121	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Stem_cells\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	RBBP8 ERI2 TTK MELK LRR1 CKAP2L DIAPH3	1.27e-06	200	121	7	31dd81df9aa754a1e69b905bf9b8ce73ff8175aa
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Stem_cells-Neuroepithelial_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	RBBP8 ERI2 TTK MELK LRR1 CKAP2L DIAPH3	1.27e-06	200	121	7	54174a485a82480726fa06efa6e050ddea77cb3c
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_ventral_progenitors\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	RBBP8 TTK MELK LRR1 CKAP2L DIAPH3 MYBL1	1.27e-06	200	121	7	9359faa749f41aaef70b4874f20b4eed2dc12cc2
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FBLN7 TTK MELK PLEKHG4B FANCB CKAP2L DIAPH3	1.27e-06	200	121	7	af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TTK MELK CKAP2L MPHOSPH9 DIAPH3 MYBL1	5.62e-06	163	121	6	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN7 TTK MELK CKAP2L DIAPH3 MYBL1	5.62e-06	163	121	6	3f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCell	Dividing_Macrophages-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	TTK MELK FANCB CKAP2L DIAPH3 HERC5	6.91e-06	169	121	6	eb0c993ef2eea73bc4881182520922ce9ae9368f
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ERI2 TTK MELK CKAP2L DIAPH3 MYBL1	6.91e-06	169	121	6	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN7 SANBR MELK CKAP2L DIAPH3 MYBL1	6.91e-06	169	121	6	121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell	facs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FUT10 ATR DYNC2H1 SMYD4 LRGUK AKAP11	7.15e-06	170	121	6	d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CASR FANCB LRGUK TIGD3 DIAPH3	7.20e-06	98	121	5	fca0baf13520c53edb6da2fe3eb152fbd44df5ed
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	TUT4 CBLB AKAP9 MACF1 TNFAIP3 CCDC144A	7.39e-06	171	121	6	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CASR TTK MELK FANCB CKAP2L DIAPH3	8.43e-06	175	121	6	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RBBP8 ERI2 TTK CKAP2L PRKG1 DIAPH3	9.00e-06	177	121	6	26c25d10aa511b64cc7db43a8deea7b5d31bca96
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PKHD1L1 ZFPM2 ASAP1 STOX2 MACF1 PRKG1	9.29e-06	178	121	6	ad3de3e03a401dac64431a541899445262246347
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ERI2 TTK MELK CKAP2L DIAPH3 MYBL1	9.90e-06	180	121	6	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A FANCC STOX2 DIAPH3 PHYHIPL L3MBTL4	1.02e-05	181	121	6	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ERI2 TTK MELK CKAP2L DIAPH3 MYBL1	1.05e-05	182	121	6	336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 SETX MPEG1 SMARCC1 MACF1 KDM6A	1.12e-05	184	121	6	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ERI2 MELK LRR1 CKAP2L DIAPH3 MYBL1	1.12e-05	184	121	6	d1e0e3b0eed2db8a5b7e3d6f81294667e4ba64e5
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	TTK MELK FANCB CKAP2L DIAPH3 MYBL1	1.16e-05	185	121	6	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN7 TTK MELK CKAP2L DIAPH3 MYBL1	1.16e-05	185	121	6	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Mega-Mast\|bone_marrow / Manually curated celltypes from each tissue	SANBR RIPOR3 ZFPM2 ZNF334 CKAP2L PRKG1	1.16e-05	185	121	6	a62ebaff92f2ed27b27b32c27c89cfbe2cb35116
ToppCell	Dividing_Macrophages-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	TTK MELK FANCB CKAP2L DIAPH3 HERC5	1.19e-05	186	121	6	0067eb78d4c7e32b9563550d9fcaf13445ee6a48
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A RIPOR3 STOX2 PRKG1 DIAPH3 PHYHIPL	1.19e-05	186	121	6	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PKHD1L1 ZFPM2 ASAP1 STOX2 MACF1 PRKG1	1.19e-05	186	121	6	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A RIPOR3 STOX2 PRKG1 DIAPH3 PHYHIPL	1.23e-05	187	121	6	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBLN7 MELK CKAP2L DIAPH3 HERC5 PCOLCE	1.31e-05	189	121	6	fd8834d1feb7f63911c5fa51efb1f679a8baddeb
ToppCell	ILEUM-non-inflamed-(1)_T_cell-(1)_CD8_Trm\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	APBA2 CBLB AKAP9 MPHOSPH9 TNFAIP3 MYBL1	1.31e-05	189	121	6	2c8a2fb76ea002bac554bc1c761ce960b5e116e1
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	TTK MELK CCDC138 CKAP2L MPHOSPH9 DIAPH3	1.35e-05	190	121	6	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	3'_v3-GI_small-bowel-Myeloid_Mac-Cycling_Myeloid-Mac\|GI_small-bowel / Manually curated celltypes from each tissue	MPEG1 TTK MELK ITGB2 CKAP2L DIAPH3	1.39e-05	191	121	6	c3944332c5226b0113f8aa9ac07837b755606c6c
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RBBP8 MELK FANCB CKAP2L DIAPH3 HERC5	1.39e-05	191	121	6	50854384fdaa0efa2e3227659d544ed09ac102f2
ToppCell	(3)_Macrophage_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ERI2 TTK MELK CKAP2L DIAPH3 HERC5	1.39e-05	191	121	6	b42f0b89bb94fd43786ff50f1caeb3ebfbbb43fd
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TTK MELK FANCB CKAP2L DIAPH3 MYBL1	1.51e-05	194	121	6	f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell	IPF-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	APBA2 PKHD1L1 NHSL1 STOX2 PRKG1 L3MBTL4	1.56e-05	195	121	6	de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCell	tumor_Lung-B_lymphocytes-GC_B_cells_in_the_DZ\|B_lymphocytes / Location, Cell class and cell subclass	TTK MELK CKAP2L DIAPH3 CCDC144A MYBL1	1.56e-05	195	121	6	339e81a3a5b1f71c0d15ef1ef0f6999378704923
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	TTK MELK LRR1 CKAP2L DIAPH3 MYBL1	1.61e-05	196	121	6	5905f0e3061a6b98b7a33d64c782c3dda2cd51ef
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RBL2 APBA2 CBLB OPTN MACF1 MYBL1	1.61e-05	196	121	6	0f3c7fd450aaa1f866b8558692534c0ea2a34e75
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RBL2 APBA2 CBLB OPTN MACF1 MYBL1	1.61e-05	196	121	6	4e1f8828413896ab8a4ec92a89d6789e8e37e05a
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FBLN7 TTK MELK FANCB CKAP2L DIAPH3	1.65e-05	197	121	6	84ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCell	COVID-19_Severe-T/NK_proliferative\|COVID-19_Severe / Disease condition and Cell class	RBBP8 TTK MELK LRR1 CKAP2L DIAPH3	1.65e-05	197	121	6	718a84e9a8248080f2d964e7c6a3ba183ece9592
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FBLN7 TTK MELK FANCB CKAP2L DIAPH3	1.65e-05	197	121	6	8b616cde333bdbc0c591035ad9e4949155866245
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	MYO9A NHSL1 STOX2 PRKG1 KDM6A L3MBTL4	1.70e-05	198	121	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	TTK MELK OPTN CKAP2L DIAPH3 MYBL1	1.70e-05	198	121	6	80b105a7c7d00ea3b5e586831fbb755bd84f9d1a
ToppCell	Caecum-B_cell-B_cell_cycling\|B_cell / Region, Cell class and subclass	ERI2 TTK MELK LRR1 CKAP2L DIAPH3	1.70e-05	198	121	6	d2def132f3efe9305a5501a96ec82efb1f02c3f7
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TTK MELK OPTN CKAP2L DIAPH3 MYBL1	1.70e-05	198	121	6	c73e906d2d12d6eba0e606958be16e63a2292cd0
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TTK MELK FANCB LRR1 CKAP2L DIAPH3	1.70e-05	198	121	6	6981cd5b1585c8ae6febdf0c4fb83067127f106c
ToppCell	T_cells-GZMK+GZMB+_T_cells\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	RBBP8 ERI2 TTK MELK CKAP2L DIAPH3	1.70e-05	198	121	6	085ba270f9defbf5ef45108c6d870e1d7c428479
ToppCell	VE-cycling\|VE / Condition, Cell_class and T cell subcluster	RBBP8 TTK MELK LRR1 CKAP2L DIAPH3	1.75e-05	199	121	6	47c47ebc318a0b98841ca2656837bbd068899559
ToppCell	COVID-19-Lymphoid-Proliferating_CD4_T_cells\|Lymphoid / Condition, Lineage and Cell class	RBBP8 TTK MELK LRR1 CKAP2L DIAPH3	1.75e-05	199	121	6	2e9ee10a069afca5dbd9f0863cf90a66db1a6ffb
ToppCell	(2)_B_cell-(24)_B_cell_cycling\|(2)_B_cell / shred on Cell_type and subtype	TTK MELK LRR1 CKAP2L DIAPH3 MYBL1	1.75e-05	199	121	6	d5a9a8a71c4de8cbcef947943f60838731bc640b
ToppCell	NS-critical-d_16-33-Lymphoid-NKT-proliferating\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TTK MELK LRR1 CKAP2L DIAPH3 MYBL1	1.75e-05	199	121	6	31b144bb209c629e12156f4d9c9cec79baffffb9
ToppCell	COVID-19-Lymphoid-Proliferating_CD4_T_cells\|COVID-19 / Condition, Lineage and Cell class	TTK MELK LRR1 RAB33A CKAP2L DIAPH3	1.75e-05	199	121	6	e1dfc856a85a91e8f7ab8d600a8a891d16b2aefb
ToppCell	COVID-19_Mild-T/NK_proliferative\|COVID-19_Mild / Disease condition and Cell class	RBBP8 TTK MELK LRR1 CKAP2L DIAPH3	1.75e-05	199	121	6	9f9a88d2b099646c1e1a7ee3f8d39cb1a2498ad7
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_ventral_progenitors\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	TTK MELK LRR1 CKAP2L DIAPH3 MYBL1	1.75e-05	199	121	6	446cd7d960812519fe2b8e434578ef0b668c75ce
ToppCell	VE-cycling-\|VE / Condition, Cell_class and T cell subcluster	RBBP8 TTK MELK LRR1 CKAP2L DIAPH3	1.75e-05	199	121	6	c0a67149a19b65b3069dbc5261d81f658e6e39a2
ToppCell	normal_Pleural_Fluid-T/NK_cells-Undetermined\|T/NK_cells / Location, Cell class and cell subclass	RBBP8 TTK MELK LRR1 CKAP2L DIAPH3	1.75e-05	199	121	6	a0c20b97cb38e493b47a06e9501fc165a78c61b2
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_IN_Progenitors\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	TTK MELK LRR1 CKAP2L DIAPH3 MYBL1	1.75e-05	199	121	6	f315ec3fb6c0799668c9195f836a77fc0db2b615
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TTK MELK CKAP2L MPHOSPH9 DIAPH3 MYBL1	1.75e-05	199	121	6	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TTK MELK FANCB LRR1 CKAP2L DIAPH3	1.75e-05	199	121	6	616c04b0605907fb218263f2164c36cb2fa26b87
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL6A6 DYNC2H1 AKAP9 MACF1 PRKG1 PCOLCE	1.80e-05	200	121	6	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ERI2 TTK MELK CKAP2L DIAPH3 MYBL1	1.80e-05	200	121	6	4cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	ERI2 TTK MELK CKAP2L DIAPH3 MYBL1	1.80e-05	200	121	6	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	metastatic_Lymph_Node-T/NK_cells-Undetermined\|T/NK_cells / Location, Cell class and cell subclass	RBBP8 TTK MELK LRR1 CKAP2L DIAPH3	1.80e-05	200	121	6	9c2095dcf70f1288d55d0ff4a97efd4fd8d0c9ee
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SETX BPTF AKAP9 MACF1 TNFAIP3 HERC5	1.80e-05	200	121	6	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CBLB OPTN AKAP9 MACF1 TNFAIP3 MYBL1	1.80e-05	200	121	6	109f673a4967ffa52270a0b4f818b3461288db44
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	TTK MELK LRR1 CKAP2L DIAPH3 MYBL1	1.80e-05	200	121	6	cea58274efbe7f9e3c3ef9fbb768ebfb917e21d9
ToppCell	Severe-T/NK_proliferative\|World / Disease group and Cell class	RBBP8 TTK MELK LRR1 CKAP2L DIAPH3	1.80e-05	200	121	6	128d82eb4d5760adf872212d8e8b5787a889969f
ToppCell	MS-IIF-Lymphocyte-T/NK-T/NK_proliferative\|IIF / Disease, condition lineage and cell class	RBBP8 TTK MELK LRR1 CKAP2L DIAPH3	1.80e-05	200	121	6	c7c1806a1054b2b034a26a18aac93fc3bec4dbc8
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	COL6A6 DYNC2H1 AKAP9 MACF1 PRKG1 PCOLCE	1.80e-05	200	121	6	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	tumor_Lung-T/NK_cells-Undetermined\|T/NK_cells / Location, Cell class and cell subclass	RBBP8 TTK MELK LRR1 CKAP2L DIAPH3	1.80e-05	200	121	6	a1ef1b4824b2d56f6b2af15d698f58fc5590c392
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	CEP76 TTK FANCB LRR1 CKAP2L MYBL1	1.80e-05	200	121	6	0bba93f1271dac704dddcdea8cb0f84a7ac6f42a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells-Neuroepithelial_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	CEP76 TTK FANCB LRR1 CKAP2L MYBL1	1.80e-05	200	121	6	c9479452ab8c51139522383f745f02171ebbd7e2
ToppCell	LPS-antiTNF-Unknown\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TTK MELK DIAPH3 MYBL1 AGAP2	2.73e-05	129	121	5	739b263296c28554967362060b154f7a95e1341d
ToppCell	LPS-antiTNF-Unknown-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TTK MELK DIAPH3 MYBL1 AGAP2	2.83e-05	130	121	5	615c233c7c2600c1c2bc5cf5b1c501fc474564ef
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CCDC60 TTK MELK CKAP2L DIAPH3	3.28e-05	134	121	5	4d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-Proliferative_Immature_MyoFibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	COL6A6 APBA2 ZFPM2 CASP12 RAB33A	3.40e-05	135	121	5	ed0f94d3839eea3b60217c4352159ed481361f13
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c3-LAMP3\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PITPNM2 INO80 ZNF181 EBF2 LRR1	3.90e-05	139	121	5	bb2b020dda32ddc60ec9952de5b01acee60b5b59
ToppCell	Control-B_naive-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 SETX AGO2 NBPF11 MACF1	6.55e-05	155	121	5	0a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN7 MELK FANCB CKAP2L DIAPH3	6.76e-05	156	121	5	955547dfeb1b1ad4957b4338701055726b22619f
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	PDXDC1 CBLB MACF1 TNFAIP3 KDM6A	6.76e-05	156	121	5	1545169694f686d28648a68b552c2ae606599d66
ToppCell	Severe-B_naive-1\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 SETX RBL2 MPEG1 MACF1	7.39e-05	159	121	5	2881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TUT4 CLHC1 SMYD4 ASXL3 CCDC144A	7.84e-05	161	121	5	8aaca49b53a551395f4025ac4e535c7b0ce41a49
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TUT4 CLHC1 SMYD4 ASXL3 CCDC144A	7.84e-05	161	121	5	deb10628d258fb813c293f81fb71be8e383dc82a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TTK MELK CKAP2L DIAPH3 MYBL1	8.81e-05	165	121	5	eec2d327c94832d1390314c93ef6a2be4648478b
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SETX CBLB BPTF AKAP9 MACF1	1.25e-05	49	67	5	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Computational	Neighborhood of ERBB2IP	TBC1D15 DICER1 WDR11 MTMR2 MACF1	5.00e-05	65	67	5	GCM_ERBB2IP
Drug	Clorgyline	TBC1D15 DYNC2H1 STXBP4 NSRP1 THAP2 AKAP9 AKAP11 BRWD1	3.30e-06	168	121	8	ctd:D003010
Drug	Imipramine hydrochloride [113-52-0]; Up 200; 12.6uM; PC3; HT_HG-U133A	CASP4 CBLB CHIC2 OPTN TNFAIP3 KDM6A CXCL12 BRWD1	7.86e-06	189	121	8	1807_UP
Drug	carmustine; Up 200; 100uM; MCF7; HT_HG-U133A	ATR CEP76 CHIC2 TAX1BP1 MTMR2 MPHOSPH9 KDM6A BRWD1	8.82e-06	192	121	8	6914_UP
Drug	Tolmetin sodium salt dihydrate [64490-92-2]; Down 200; 12.6uM; HL60; HT_HG-U133A	ZSWIM8 TRAF3IP1 CASP4 CASR NEDD4 RAB33A MLH3 KDM6A	1.06e-05	197	121	8	3009_DN
Drug	Cefoxitin sodium salt [33564-30-6]; Down 200; 8.8uM; PC3; HT_HG-U133A	SETX APBA2 MELK TAX1BP1 MTMR2 MACF1 KDM6A GOLGA3	1.14e-05	199	121	8	7148_DN
Disease	FANCONI ANEMIA, COMPLEMENTATION GROUP C	FANCC FANCB	1.56e-05	2	117	2	C3468041
Disease	Leukemia, Myelocytic, Acute	CBL CBLB FANCC FANCB CHIC2 ASXL2	6.80e-05	173	117	6	C0023467
Disease	macula measurement	PITPNM2 MYO9A INO80 TTK BPTF STOX2	1.11e-04	189	117	6	EFO_0008375
Disease	adenoid cystic carcinoma (is_implicated_in)	ATR KDM6A	1.55e-04	5	117	2	DOID:0080202 (is_implicated_in)
Disease	glutathione peroxidase 7 measurement	TUT4 ZFPM2	2.31e-04	6	117	2	EFO_0801635
Disease	Bladder Neoplasm	ASAP1 FANCC BPTF ASXL2 KDM6A	2.45e-04	140	117	5	C0005695
Disease	Malignant neoplasm of urinary bladder	ASAP1 FANCC BPTF ASXL2 KDM6A	2.53e-04	141	117	5	C0005684
Disease	Dickkopf-related protein 4 measurement	ZFPM2 PRKG1	4.30e-04	8	117	2	EFO_0008110
Disease	allergic rhinitis (biomarker_via_orthology)	ITGB2 PRKG1	6.87e-04	10	117	2	DOID:4481 (biomarker_via_orthology)
Disease	Oligospermia	DICER1 BRWD1	1.00e-03	12	117	2	C0028960
Disease	dickkopf‐related protein 1 measurement	ZFPM2 PRKG1	1.00e-03	12	117	2	EFO_0010620
Disease	factor VII measurement	NEDD4 OPTN L3MBTL4	1.37e-03	55	117	3	EFO_0004619
Disease	Fanconi anemia	FANCC FANCB	1.38e-03	14	117	2	cv:C0015625
Disease	Majewski Syndrome	TRAF3IP1 DYNC2H1	1.38e-03	14	117	2	C0024507
Disease	colorectal cancer (is_implicated_in)	DICER1 MLH3 TNFAIP3 KDM6A	1.40e-03	121	117	4	DOID:9256 (is_implicated_in)
Disease	matrix metalloproteinase 1 measurement	ZFPM2 CKAP2L	1.58e-03	15	117	2	EFO_0010588
Disease	Neoplasm of uncertain or unknown behavior of bladder	FANCC KDM6A	1.58e-03	15	117	2	C0496930
Disease	Benign neoplasm of bladder	FANCC KDM6A	1.58e-03	15	117	2	C0154017
Disease	Carcinoma in situ of bladder	FANCC KDM6A	1.58e-03	15	117	2	C0154091
Disease	Dermatitis	ITGB2 CXCL12	1.80e-03	16	117	2	C0011603
Disease	Amyotrophic lateral sclerosis	SETX OPTN	2.04e-03	17	117	2	cv:C0002736
Disease	matrix metalloproteinase 12 measurement	DYNC2H1 CASP12	2.29e-03	18	117	2	EFO_0010590
Disease	Bone marrow hypocellularity	FANCC FANCB	2.29e-03	18	117	2	C1855710
Disease	Carcinoma of bladder	FANCC KDM6A	2.29e-03	18	117	2	C0699885
Disease	MYELODYSPLASTIC SYNDROME	CBL FANCC FANCB	2.42e-03	67	117	3	C3463824
Disease	Congenital Myasthenic Syndromes, Presynaptic	MYO9A PREPL	2.55e-03	19	117	2	C0751884
Disease	type 1 diabetes mellitus (biomarker_via_orthology)	CBL CASP12	2.55e-03	19	117	2	DOID:9744 (biomarker_via_orthology)
Disease	Seckel syndrome	ATR RBBP8	3.42e-03	22	117	2	C0265202
Disease	calcium measurement	PITPNM2 SANBR CASR CBL ZFPM2 GPX6 MACF1 PRKG1	3.61e-03	628	117	8	EFO_0004838

Protein segments in the cluster

Peptide	Gene	Start	Entry
KSICANSPIKAQQDQ	ERI2	296	A8K979
NNCNPLTKESIRQKE	DCAF4	86	Q8WV16
RQKLQCVASKLQVLP	AKAP9	3516	Q99996
LNPCRTGKIKSLQNN	RBBP8	631	Q99708
QIFNNRNCLSLKDKP	CASP4	236	P49662
SQQQPRCKQKVIFGS	CASR	956	P41180
LKCNQNCLKTAGNPR	EBF2	191	Q9HAK2
PKVKNPCLNVQSQRS	AKAP11	1226	Q9UKA4
KQQQLLAACKSLPSS	AGAP2	571	Q99490
LKNQTQVKLNIVSCP	APBA2	641	Q99767
KKQRPLTASLQCNST	CGGBP1	81	Q9UFW8
QPICFDRQSTLKKTN	CEP76	86	Q8TAP6
SQRPVLKVCNHENQK	DIAPH3	1096	Q9NSV4
KALCPTRENFNSQQK	DICER1	1601	Q9UPY3
RPVNKCSDQIKLKNT	BPTF	1496	Q12830
NNRNCQSLKDKPKVI	CASP12	201	Q6UXS9
KKQQQQCRPSISISS	ASXL2	176	Q76L83
QQKRLLPSCSFQQNL	ASXL3	1896	Q9C0F0
TPQTLSNLCLKINVK	AGO2	556	Q9UKV8
LTNASQCQPVQPKKE	CCNB3	66	Q8WWL7
PVQKKSKNRTNCDIN	CCDC60	361	Q8IWA6
NKCDLREQIQVPSNL	RAB33A	151	Q14088
VSSKNRIPQEKCILQ	NSRP1	221	Q9H0G5
DQILTNLSKRKCPSQ	PCOLCE	426	Q15113
AALQAQKNCKETLPR	INO80	321	Q9ULG1
NRDVLLCQKLEQKNP	MPEG1	391	Q2M385
ALCRTPANKLKNKEN	MELK	411	Q14680
LQCSNRKELVNPNFK	RBL2	241	Q08999
CRNKPNQFIRIKNNI	ANKAR	1296	Q7Z5J8
QLNALLEQESRCQPK	CCNG1	16	P51959
LAQLNKCTSPQQKLV	ANKRD27	271	Q96NW4
QRKQRDCVNQCKSKP	MBD3L1	6	Q8WWY6
IKQTQCPADPLQLNK	FEM1C	426	Q96JP0
PRASQNCLSKQQLLS	FBLN7	21	Q53RD9
TLKLNPLQENCNAVR	FAM189A1	156	O60320
LRCENIQPNPTEKQK	TRAF3IP1	406	Q8TDR0
RKQQNEVSSCIPKIL	HAUS2	191	Q9NVX0
NKKSSCLQISLQPTR	NEDD4	81	P46934
LPVQFCQLQELKNLK	LRR1	241	Q96L50
KPKAAEVCQQSNQKR	GPR158	1051	Q5T848
NAANLIKKLCRDNPS	PRKG1	586	Q13976
CEKKTQLFLTNQRPE	ZFPM2	441	Q8WW38
LCNLPQGSLQNKTKL	KDM6A	401	O15550
VVRLCQNPKLQLKNS	CBLB	56	Q13191
RRIPKKSSQCNGQVL	NHSL1	686	Q5SYE7
PATKCPNSKLNLNQL	MCF2L2	271	Q86YR7
SGQLPNKKNCRTNIS	MLH3	666	Q9UHC1
RNFPELLSLNLCNNK	NXF5	156	Q9H1B4
CQLSQRLQESLKKVN	PDXDC1	361	Q6P996
NASRSPEKCAQQRQK	MPHOSPH9	781	Q99550
PEKCAQQRQKRLNSA	MPHOSPH9	786	Q99550
LCNSEQQRGKENLPK	MTMR2	521	Q13614
EKVNSQPRLVQQAKC	L3MBTL4	451	Q8NA19
NKLPIKILCLSNNQI	LRGUK	256	Q96M69
GRPTKKLQQQCQFIT	PITPNM2	1231	Q9BZ72
SKEPLKNLNSCLQQL	GOLGA3	1421	Q08378
QAKNCPISAKLERLQ	MACF1	4821	Q9UPN3
LKCQNRVIKLSTNPF	FANCB	521	Q8NB91
KLHRVNQVKCQLPES	HERC5	576	Q9UII4
QLSNNPVKGRTCKER	ITGB2	651	P05107
VQKLASALLNQKCPL	DYNC2H1	4111	Q8NCM8
QQNSCNRVPKILIDK	ATR	681	Q13535
NNRNCLSLKDKPKVI	CASP5	296	P51878
SQRNDIQEKCVKLLP	CCDC138	391	Q96M89
NIPCAVTKRNNLRKA	C6	496	P13671
KSNLPLNKTQQFNIC	CEP126	1046	Q9P2H0
CLRNKDLPQQLKNPA	FUT10	246	Q6P4F1
CLINKEPQNSGQSKL	FANCC	96	Q00597
RLKGCENKQPQKTSQ	CCDC144B	236	Q3MJ40
ASINRVNSCLKKNLP	CHIC2	66	Q9UKJ5
QQCKINVRDSENKSP	ANKRD7	81	Q92527
ENKSPLIKAVQCQNE	ANKRD7	91	Q92527
SNRQPAKLNLLTCQV	ASAP1	361	Q9ULH1
RQNCKGDSQPNKSIR	BRWD1	1441	Q9NSI6
VVRLCQNPKLALKNS	CBL	66	P22681
RLKGCENKQPQKTSQ	CCDC144A	236	A2RUR9
QTLKPQNRKVDCNKG	GPX6	21	P59796
STPEQLSKRLQNFCK	GTDC1	406	Q4AE62
RCNLIPEKQDINSTN	MYBL1	671	P10243
INLKIKCNRLNSIDP	COL6A6	2176	A6NMZ7
LRILTCEPSQNKQKG	PRIMPOL	341	Q96LW4
QEKCQALERKNSAIP	OPTN	331	Q96CV9
CKQRLPQLNSKDNKF	PHYHIPL	296	Q96FC7
CQRLQKQINKLSDQS	TAX1BP1	456	Q86VP1
NKDICLPESNNQVKT	SMYD4	376	Q8IYR2
QCSQKKAQKITELRP	SMARCAD1	406	Q9H4L7
CVPNLQRLNLDSNKL	LRRTM3	276	Q86VH5
CPQLAEKKQQFRSLK	NBPF8	261	Q3BBV2
CPQLAEKKQQFRSLK	NBPF11	296	Q86T75
TVANLNRIKLNSKQC	TAF2	56	Q6P1X5
AKIKQNRVLVCAPSN	SETX	1996	Q7Z333
AKNPNLRKNVLCGNI	TCEA1	201	P23193
CNQKVLRFDPTQLTK	SANBR	441	Q6NSI8
IRQKSDNIQPENLSC	STXBP4	106	Q6ZWJ1
EKTLVQNNCLTRPNI	SMARCC1	156	Q92922
RQQIKDFTCNPLNSI	DZIP1	436	Q86YF9
LIQCLTKELNEKQPS	CLHC1	476	Q8NHS4
KNNCQNQPPSKSTIR	CKAP2L	41	Q8IYA6
SCVLQKSKAISQRPN	CKAP2L	366	Q8IYA6
SQPQISRICKNKEKL	TIGD3	41	Q6B0B8
TQKGRQTERKPNECN	ZNF334	226	Q9HCZ1
ECSERRQKNQNKLPK	TNFAIP3	406	P21580
LQVCKALLQKLASPN	RIPOR3	626	Q96MK2
CQKGLQLAKENPQRT	PLEKHG4B	476	Q96PX9
TNEAEKLQKPSNCLQ	STOX2	906	Q9P2F5
QTPSCKIQKLSLQNC	RNH1	81	P13489
CLQNKPKISELARNI	PREPL	51	Q4J6C6
PLCSLNNTRVKNSKR	PKHD1L1	1541	Q86WI1
SPQDKRTLLVNCQNK	TBC1D15	186	Q8TC07
KIQQCVVANKLPRNR	ZNF770	11	Q6IQ21
PLTCNKNLTHRKDQQ	ZNF677	121	Q86XU0
ALNPNEIQRALVQCK	ZSWIM8	1371	A7E2V4
RNSLRQTNKTKQSCP	TTK	256	P33981
LKSRNLLKKNNSCSP	THAP2	91	Q9H0W7
NSKRSLKQPLEQNQT	ZNF148	396	Q9UQR1
QCLSKTQQKSRELNN	VEZT	411	Q9HBM0
HSPNQRLLKSVQQCN	ZNF614	91	Q8N883
LCSPQVNQKSKALLV	WDR11	1116	Q9BZH6
VKSKLCNLRNLPPQA	POLR1B	141	Q9H9Y6
NTPNCALQIVARLKN	CXCL12	51	P48061
ARLKNNNRQVCIDPK	CXCL12	61	P48061
GEKCALQNSPRSQKQ	TUT4	201	Q5TAX3
SPQLDTQQEIKLCQK	WDR41	266	Q9HAD4
QPVKKQQENATSCSL	WDR41	381	Q9HAD4
ISQPCQKSSQLCQKV	PPIP5K1	1306	Q6PFW1
RQKPCIVKNVENLLN	ZNF506	421	Q5JVG8
QGKSLTLPQTCNREK	ZNF181	221	Q2M3W8
CLKESPNKQQERAQS	MYO9A	1226	B2RTY4