Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpoly-purine tract binding

FMR1 PABPN1L DDX3X PABPN1 SYNCRIP

1.70e-05371755GO:0070717
GeneOntologyMolecularFunctionsingle-stranded RNA binding

FMR1 PABPN1L DDX3X AGO4 AGO3 PABPN1 SYNCRIP

5.56e-051111757GO:0003727
GeneOntologyMolecularFunctionoxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor

GMPR2 GMPR

7.64e-0521752GO:0046857
GeneOntologyMolecularFunctionGMP reductase activity

GMPR2 GMPR

7.64e-0521752GO:0003920
GeneOntologyMolecularFunctionpoly(A) binding

PABPN1L DDX3X PABPN1 SYNCRIP

1.14e-04291754GO:0008143
GeneOntologyMolecularFunctioncalcium ion binding

NID2 HSPG2 GALNT3 PAMR1 EFEMP2 ACTN2 ACTN3 CUBN PKD1L3 DYSF F9 CD93 THBS2 FAT1 NECAB1 ADGRE4P ASTN2

3.26e-0474917517GO:0005509
GeneOntologyCellularComponentGMP reductase complex

GMPR2 GMPR

6.81e-0521732GO:1902560
DomainEGF-like_Ca-bd_dom

NID2 HSPG2 PAMR1 EFEMP2 CUBN F9 CD93 THBS2 FAT1 ADGRE4P

2.76e-0712417610IPR001881
DomainEGF_CA

NID2 HSPG2 PAMR1 EFEMP2 CUBN F9 CD93 THBS2 FAT1

2.34e-061221769SM00179
DomainEGF

NID2 HSPG2 PAMR1 EFEMP2 LAMA1 CUBN F9 CD93 THBS2 FAT1 FCGBP ADGRE4P

2.43e-0623517612SM00181
DomainC8

MUC19 MUC5B FCGBP MUC5AC

3.56e-06121764PF08742
DomainTIL

MUC19 MUC5B FCGBP MUC5AC

3.56e-06121764PF01826
DomainEGF-like_dom

NID2 HSPG2 PAMR1 EFEMP2 LAMA1 CUBN F9 CD93 THBS2 FAT1 FCGBP ADGRE4P

4.41e-0624917612IPR000742
DomainUnchr_dom_Cys-rich

MUC19 MUC5B FCGBP MUC5AC

5.10e-06131764IPR014853
DomainC8

MUC19 MUC5B FCGBP MUC5AC

5.10e-06131764SM00832
DomainCUB

PAMR1 CDCP2 CUBN CSMD2 CSMD1 DCBLD2

6.42e-06491766PF00431
DomainTIL_dom

MUC19 MUC5B FCGBP MUC5AC

7.09e-06141764IPR002919
DomainCUB

PAMR1 CDCP2 CUBN CSMD2 CSMD1 DCBLD2

7.24e-06501766SM00042
DomainEGF_2

NID2 HSPG2 PAMR1 EFEMP2 LAMA1 CUBN F9 CD93 THBS2 FAT1 ASTN2 EPHA8

8.32e-0626517612PS01186
Domain-

PAMR1 CDCP2 CUBN CSMD2 CSMD1 DCBLD2

9.14e-065217662.60.120.290
DomainSushi

PAMR1 CSMD2 F13B HP C4BPA CSMD1

9.14e-06521766PF00084
DomainCUB

PAMR1 CDCP2 CUBN CSMD2 CSMD1 DCBLD2

1.02e-05531766PS01180
DomainCCP

PAMR1 CSMD2 F13B HP C4BPA CSMD1

1.14e-05541766SM00032
DomainVWF_type-D

MUC19 MUC5B FCGBP MUC5AC

1.27e-05161764IPR001846
DomainVWFD

MUC19 MUC5B FCGBP MUC5AC

1.27e-05161764PS51233
DomainVWD

MUC19 MUC5B FCGBP MUC5AC

1.27e-05161764SM00216
DomainVWD

MUC19 MUC5B FCGBP MUC5AC

1.27e-05161764PF00094
DomainSUSHI

PAMR1 CSMD2 F13B HP C4BPA CSMD1

1.41e-05561766PS50923
DomainEGF_3

NID2 HSPG2 PAMR1 EFEMP2 CUBN F9 CD93 THBS2 FAT1 ADGRE4P ASTN2

1.47e-0523517611PS50026
DomainSushi_SCR_CCP_dom

PAMR1 CSMD2 F13B HP C4BPA CSMD1

1.57e-05571766IPR000436
DomainCUB_dom

PAMR1 CDCP2 CUBN CSMD2 CSMD1 DCBLD2

1.57e-05571766IPR000859
DomainEGF_CA

NID2 EFEMP2 CUBN CD93 THBS2 FAT1 ADGRE4P

1.68e-05861767PF07645
Domain-

STXBP5L COP1 DDB1 ARPC1B WDR19 PWP1 PLXNC1 DAW1 VPS41 WDR41 WDR1 BUB3 PLXNB3

1.70e-05333176132.130.10.10
DomainWD40/YVTN_repeat-like_dom

STXBP5L COP1 DDB1 ARPC1B WDR19 PWP1 PLXNC1 DAW1 VPS41 WDR41 WDR1 BUB3 PLXNB3

1.82e-0533517613IPR015943
DomainEGF

NID2 HSPG2 PAMR1 CUBN F9 CD93 THBS2 FAT1

2.59e-051261768PF00008
DomainVWC_out

MUC19 MUC5B FCGBP MUC5AC

2.64e-05191764SM00215
DomainVWC

MUC19 MUC5B THBS2 FCGBP MUC5AC

2.74e-05381765SM00214
DomainSPR

SPRY3 SPRED3 SPRY4

2.80e-0571763PS51227
DomainSprouty

SPRY3 SPRED3 SPRY4

2.80e-0571763IPR007875
DomainSprouty

SPRY3 SPRED3 SPRY4

2.80e-0571763PF05210
DomainEGF-like_CS

NID2 HSPG2 PAMR1 EFEMP2 LAMA1 CUBN F9 CD93 THBS2 FAT1 EPHA8

3.86e-0526117611IPR013032
DomainEGF_CA

NID2 EFEMP2 CUBN F9 CD93 FAT1 ADGRE4P

4.21e-05991767PS01187
DomainASX_HYDROXYL

NID2 EFEMP2 CUBN F9 CD93 FAT1 ADGRE4P

4.49e-051001767PS00010
DomainVWF_dom

MUC19 MUC5B THBS2 FCGBP MUC5AC

4.50e-05421765IPR001007
DomainEGF-type_Asp/Asn_hydroxyl_site

NID2 EFEMP2 CUBN F9 CD93 FAT1 ADGRE4P

6.51e-051061767IPR000152
DomainGMPR

GMPR2 GMPR

8.83e-0521762IPR005993
DomainWD40_repeat_dom

STXBP5L COP1 DDB1 ARPC1B WDR19 PWP1 DAW1 VPS41 WDR41 WDR1 BUB3

1.23e-0429717611IPR017986
DomainEGF_dom

NID2 CUBN THBS2

1.70e-04121763IPR024731
DomainEGF_3

NID2 CUBN THBS2

1.70e-04121763PF12947
DomainNXF_fam

NXF3 NXF2

2.63e-0431762IPR030217
DomainEGF_Ca-bd_CS

NID2 EFEMP2 CUBN F9 CD93 FAT1

3.13e-04971766IPR018097
DomainVWFC_2

MUC19 MUC5B THBS2 MUC5AC

4.38e-04381764PS50184
DomainIMPDH

GMPR2 GMPR

5.23e-0441762PF00478
DomainTap_RNA_bd

NXF3 NXF2

5.23e-0441762PD043466
DomainIMP_DH_GMPRt

GMPR2 GMPR

5.23e-0441762IPR001093
DomainTap_RNA-bd

NXF3 NXF2

5.23e-0441762IPR015245
DomainIMP_DH_GMP_RED

GMPR2 GMPR

5.23e-0441762PS00487
DomainIMP_DH/GMP_Rdtase_CS

GMPR2 GMPR

5.23e-0441762IPR015875
DomainArgonaute_N

AGO4 AGO3

5.23e-0441762IPR032474
DomainArgonaute_Mid_dom

AGO4 AGO3

5.23e-0441762IPR032473
DomainArgoL2

AGO4 AGO3

5.23e-0441762IPR032472
DomainTap-RNA_bind

NXF3 NXF2

5.23e-0441762PF09162
DomainArgoN

AGO4 AGO3

5.23e-0441762PF16486
DomainArgoMid

AGO4 AGO3

5.23e-0441762PF16487
DomainArgoL2

AGO4 AGO3

5.23e-0441762PF16488
DomainCTCK_1

MUC19 MUC5B MUC5AC

6.05e-04181763PS01185
DomainGrowth_fac_rcpt_

NID2 HSPG2 EFEMP2 LAMA1 CUBN CD93 FAT1

7.02e-041561767IPR009030
DomainEGF_1

HSPG2 PAMR1 EFEMP2 LAMA1 CUBN F9 THBS2 FAT1 ASTN2

7.19e-042551769PS00022
DomainWD40

STXBP5L COP1 ARPC1B WDR19 PWP1 DAW1 WDR41 WDR1 BUB3

8.02e-042591769PF00400
DomainHnRNP_R/Q_splicing_fac

SYNCRIP HNRNPR

8.67e-0451762IPR006535
DomainDUF1785

AGO4 AGO3

8.67e-0451762SM01163
DomainWD40

STXBP5L COP1 ARPC1B WDR19 PWP1 DAW1 WDR41 WDR1 BUB3

1.02e-032681769SM00320
DomainCT

MUC19 MUC5B MUC5AC

1.11e-03221763SM00041
DomainWD40_repeat

STXBP5L COP1 ARPC1B WDR19 PWP1 DAW1 WDR41 WDR1 BUB3

1.13e-032721769IPR001680
DomainG-protein_beta_WD-40_rep

PWP1 DAW1 WDR41 WDR1 BUB3

1.25e-03851765IPR020472
DomainSpectrin

KALRN ACTN2 ACTN3

1.27e-03231763PF00435
DomainACTININ_2

FLNA ACTN2 ACTN3

1.27e-03231763PS00020
DomainACTININ_1

FLNA ACTN2 ACTN3

1.27e-03231763PS00019
DomainActinin_actin-bd_CS

FLNA ACTN2 ACTN3

1.27e-03231763IPR001589
DomainEFhand_Ca_insen

ACTN2 ACTN3

1.29e-0361762PF08726
DomainHaem_d1

STXBP5L WDR19

1.29e-0361762IPR011048
DomainArgoL1

AGO4 AGO3

1.29e-0361762PF08699
DomainEF-hand_Ca_insen

ACTN2 ACTN3

1.29e-0361762IPR014837
DomainArgoL1

AGO4 AGO3

1.29e-0361762IPR014811
DomainWxxW_domain

MUC5B MUC5AC

1.29e-0361762IPR025155
DomainMucin2_WxxW

MUC5B MUC5AC

1.29e-0361762PF13330
DomainWD_REPEATS_1

STXBP5L COP1 ARPC1B WDR19 PWP1 DAW1 WDR41 WDR1 BUB3

1.32e-032781769PS00678
DomainWD_REPEATS_2

STXBP5L COP1 ARPC1B WDR19 PWP1 DAW1 WDR41 WDR1 BUB3

1.35e-032791769PS50082
DomainWD_REPEATS_REGION

STXBP5L COP1 ARPC1B WDR19 PWP1 DAW1 WDR41 WDR1 BUB3

1.35e-032791769PS50294
DomainRho_GTPase_activation_prot

ARHGAP10 ARHGAP17 PLXNC1 PLXNB3 ARHGAP33

1.46e-03881765IPR008936
Domain-

IL10RB HSPG2 FLNA KALRN MXRA8 FNDC3A DSCAML1 NPTN AMIGO3 TIGIT PLXNC1 ASTN2 FGFR3 PLXNB3 EPHA8

1.56e-03663176152.60.40.10
DomainCys_knot_C

MUC19 MUC5B MUC5AC

1.62e-03251763IPR006207
DomainCTCK_2

MUC19 MUC5B MUC5AC

1.62e-03251763PS01225
DomainClathrin

WDR19 VPS41

1.80e-0371762PF00637
DomaincEGF

NID2 EFEMP2 CD93

1.82e-03261763PF12662
DomaincEGF

NID2 EFEMP2 CD93

1.82e-03261763IPR026823
DomainLaminin_G

HSPG2 LAMA1 THBS2 FAT1

2.18e-03581764IPR001791
DomainKelch

LZTR1 KLHL32 KLHL8 KLHL17

2.18e-03581764SM00612
DomainVWC

MUC5B THBS2 MUC5AC

2.27e-03281763PF00093
DomainPIWI

AGO4 AGO3

2.38e-0381762PS50822
DomainClathrin_H-chain/VPS_repeat

WDR19 VPS41

2.38e-0381762IPR000547
DomainPiwi

AGO4 AGO3

2.38e-0381762SM00950
DomainNuclear_transport_factor_2_euk

NXF3 NXF2

2.38e-0381762IPR018222
DomainNTF2

NXF3 NXF2

2.38e-0381762PF02136
DomainPiwi

AGO4 AGO3

2.38e-0381762PF02171
DomainLAMININ_IVA

HSPG2 LAMA1

2.38e-0381762PS51115
DomainLaminin_B

HSPG2 LAMA1

2.38e-0381762PF00052
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

HSPG2 FLNA PSAT1 KALRN MXRA8 CUBN PKD1L3 DYSF DDB1 F11 DDX3X FAT1 FCGBP ARSL HP GSTCD GM2A WDR1 BBOX1

1.30e-0610161781919056867
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC19 MUC5B MUC5AC

2.61e-066178319110483
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HSPG2 FLNA LZTR1 PCNX3 KALRN ARHGAP17 DYSF DENND1A URB1 FAT1 SIRT2 MTHFR XXYLT1 ANKRD11 PDZD8 SSBP4 TTC5 ARHGAP33 KLHL17

4.40e-0611051781935748872
Pubmed

Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme.

SPRY3 SPRED3 SPRY4 FGFR3

5.44e-0623178420934536
Pubmed

A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.

LZTR1 MUC19 PLXNC1 ABTB1 KLHL8 KLHL17

5.92e-0687178637495603
Pubmed

Specific ablation of the nidogen-binding site in the laminin gamma1 chain interferes with kidney and lung development.

NID2 HSPG2 LAMA1

7.24e-068178312015298
Pubmed

Calsarcins, a novel family of sarcomeric calcineurin-binding proteins.

FLNA ACTN2 ACTN3

1.08e-059178311114196
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

CARM1 FLNA FMR1 PPP1R12A DDB1 DDX3X AGO3 SYNCRIP HNRNPR

1.30e-05274178934244482
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

FLNA FMR1 KALRN SEPTIN9 PPP1R12A DPYSL5 ACTN2 ACTN3 DDB1 ARPC1B USP31 NPTN SIRT2 SACS DDX3Y PLCL1 WDR1 CAMSAP2 SYNCRIP HNRNPR CDK5

1.51e-0514311782137142655
Pubmed

TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules.

FMR1 DDX3X DDX3Y

1.54e-0510178318632687
Pubmed

Interaction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycans.

HSPG2 LAMA1 CD93

1.54e-051017839136074
Pubmed

Systematic and quantitative assessment of the ubiquitin-modified proteome.

PSAT1 DDB1 SPRYD7 AGO3 PABPN1 SYNCRIP HNRNPR

1.82e-05158178721906983
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

CARM1 NID2 HSPG2 FLNA EFEMP2 MXRA8 DPM3 RNF213 GMPR2 DDB1 DDX3X NPTN THBS2 FAT1 NT5DC2 XXYLT1 PDZD8 RARS2 TMED2 MAP4K4 SYNCRIP

1.86e-0514511782130550785
Pubmed

FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A.

ARPC1B DDX3X PWP1 WDR1

1.87e-0531178436159747
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

NID2 LZTR1 FMR1 DIS3L ARHGAP10 PPP1R12A HTATIP2 RNF213 DDB1 FAT1 AGO3 MTHFR NT5DC2 RARS2 CHPF2 CSMD1 SLC25A19 ARHGAP33

1.87e-0511161781831753913
Pubmed

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

MUC5B MUC5AC

2.60e-05217827513696
Pubmed

Polymorphisms in the methylenetetrahydrofolate reductase and methionine synthase reductase genes and homocysteine levels in Brazilian children.

MTHFR MTRR

2.60e-052178215216546
Pubmed

Esophageal and gastric cardia cancer risk and folate- and vitamin B(12)-related polymorphisms in Linxian, China.

MTHFR MTRR

2.60e-052178214652285
Pubmed

The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.

MUC5B MUC5AC

2.60e-052178237146737
Pubmed

MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.

MUC5B MUC5AC

2.60e-052178214988081
Pubmed

Methionine synthase reductase 66A->G polymorphism is associated with increased plasma homocysteine concentration when combined with the homozygous methylenetetrahydrofolate reductase 677C->T variant.

MTHFR MTRR

2.60e-052178215514263
Pubmed

Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.

MUC5B MUC5AC

2.60e-052178215563276
Pubmed

A sequential mechanism for exosite-mediated factor IX activation by factor XIa.

F9 F11

2.60e-052178222961984
Pubmed

The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.

MUC5B MUC5AC

2.60e-052178217621824
Pubmed

The association between MTHFR polymorphism and cervical cancer.

MTHFR MTRR

2.60e-052178229740106
Pubmed

Muc5b is required for airway defence.

MUC5B MUC5AC

2.60e-052178224317696
Pubmed

Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.

MUC5B MUC5AC

2.60e-052178222391959
Pubmed

The roles of MTRR and MTHFR gene polymorphisms in congenital heart diseases: a meta-analysis.

MTHFR MTRR

2.60e-052178230333252
Pubmed

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.

MUC5B MUC5AC

2.60e-052178235776514
Pubmed

Analysis of the factor XI variant Arg184Gly suggests a structural basis for factor IX binding to factor XIa.

F9 F11

2.60e-052178223617568
Pubmed

The relevance of MTHFR C677T, A1298C, and MTRR A66G polymorphisms with response to male infertility in Asians: A meta-analysis.

MTHFR MTRR

2.60e-052178230813130
Pubmed

The factor IX gamma-carboxyglutamic acid (Gla) domain is involved in interactions between factor IX and factor XIa.

F9 F11

2.60e-052178212496253
Pubmed

Associations of coagulation factors IX and XI levels with incident coronary heart disease and ischemic stroke: the REGARDS study.

F9 F11

2.60e-052178228393470
Pubmed

Severe factor XI deficiency caused by a Gly555 to Glu mutation (factor XI-Glu555): a cross-reactive material positive variant defective in factor IX activation.

F9 F11

2.60e-052178215456490
Pubmed

Polymorphisms in MTHFR and MTRR genes associated with blood plasma homocysteine concentration and sperm counts.

MTHFR MTRR

2.60e-052178220888556
Pubmed

The ocular surface phenotype of Muc5ac and Muc5b null mice.

MUC5B MUC5AC

2.60e-052178224327612
Pubmed

MTHFR and MTRR genotype and haplotype analysis and colorectal cancer susceptibility in a case-control study from the Czech Republic.

MTHFR MTRR

2.60e-052178221211571
Pubmed

The Roles of MTRR and MTHFR Gene Polymorphisms in Colorectal Cancer Survival.

MTHFR MTRR

2.60e-052178236364857
Pubmed

Specific glycoforms of MUC5AC and endorepellin accurately distinguish mucinous from nonmucinous pancreatic cysts.

HSPG2 MUC5AC

2.60e-052178223836919
Pubmed

Novel missense mutations in two patients with factor XI deficiency (Val271Leu and Tyr351Ser) and one patient with combined factor XI and factor IX deficiency (Phe349Val).

F9 F11

2.60e-052178215842381
Pubmed

Deficits in trace fear memory and long-term potentiation in a mouse model for fragile X syndrome.

FMR1 PDE6B

2.60e-052178216093389
Pubmed

A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population.

LAMA1 XXYLT1

2.60e-052178220876614
Pubmed

[Molecular genetic markers of predisposition to thrombosis in adolescents with essential hypertension ].

MTHFR MTRR

2.60e-052178225518505
Pubmed

Association between MTHFR C677T and A1298C, and MTRR A66G polymorphisms and susceptibility to schizophrenia in a Syrian study cohort.

MTHFR MTRR

2.60e-052178222813657
Pubmed

Strength, power, fiber types, and mRNA expression in trained men and women with different ACTN3 R577X genotypes.

ACTN2 ACTN3

2.60e-052178219150855
Pubmed

Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome in China.

MTHFR MTRR

2.60e-052178218257130
Pubmed

Gel-forming mucins form distinct morphologic structures in airways.

MUC5B MUC5AC

2.60e-052178228607090
Pubmed

The mechanism underlying activation of factor IX by factor XIa.

F9 F11

2.60e-052178224759143
Pubmed

Mitogen- and stress-activated protein kinase 1 activates osteoclastogenesis in vitro and affects bone destruction in vivo.

RPS6KA5 TNFSF11

2.60e-052178223619911
Pubmed

The FMRP/GRK4 mRNA interaction uncovers a new mode of binding of the Fragile X mental retardation protein in cerebellum.

FMR1 GRK4

2.60e-052178226250109
Pubmed

Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.

MUC5B MUC5AC

2.60e-052178231030254
Pubmed

Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) gene polymorphisms as risk factors for hepatocellular carcinoma in a Korean population.

MTHFR MTRR

2.60e-052178219035314
Pubmed

The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.

MUC5B MUC5AC

2.60e-052178223527003
Pubmed

α-Actinin-2 deficiency results in sarcomeric defects in zebrafish that cannot be rescued by α-actinin-3 revealing functional differences between sarcomeric isoforms.

ACTN2 ACTN3

2.60e-052178222253474
Pubmed

Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.

MUC5B MUC5AC

2.60e-052178216540890
Pubmed

alpha-actinin-3 and performance.

ACTN2 ACTN3

2.60e-052178219696509
Pubmed

Altered mossy fiber distributions in adult Fmr1 (FVB) knockout mice.

FMR1 PDE6B

2.60e-052178211918288
Pubmed

Double aneuploidy (48,XXY,+21) of maternal origin in a child born to a 13-year-old mother: evaluation of the maternal folate metabolism.

MTHFR MTRR

2.60e-052178219852428
Pubmed

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

MUC5B MUC5AC

2.60e-052178227845589
Pubmed

Association analysis of MTHFR (rs1801133 and rs1801131) and MTRR (rs1801394) gene polymorphisms towards the development of hypertension in the Bai population from Yunnan, China.

MTHFR MTRR

2.60e-052178237154151
Pubmed

Maternal polymorphisms 677C-T and 1298A-C of MTHFR, and 66A-G MTRR genes: is there any relationship between polymorphisms of the folate pathway, maternal homocysteine levels, and the risk for having a child with Down syndrome?

MTHFR MTRR

2.60e-052178216575899
Pubmed

Loss of CSMD1 or 2 may contribute to the poor prognosis of colorectal cancer patients.

CSMD2 CSMD1

2.60e-052178224408017
Pubmed

Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.

MUC5B MUC5AC

2.60e-052178227435107
Pubmed

Factor XI-deficient mice exhibit increased bleeding after injury to the saphenous vein.

F9 F11

2.60e-052178228677246
Pubmed

Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.

MUC5B MUC5AC

2.60e-052178226871672
Pubmed

Differential regulation of Actn2 and Actn3 expression during unfolded protein response in C2C12 myotubes.

ACTN2 ACTN3

2.60e-052178232451822
Pubmed

Cloning and characterization of two human skeletal muscle alpha-actinin genes located on chromosomes 1 and 11.

ACTN2 ACTN3

2.60e-05217821339456
Pubmed

CDK5-mediated phosphorylation of Sirt2 contributes to depressive-like behavior induced by social defeat stress.

SIRT2 CDK5

2.60e-052178229158185
Pubmed

In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.

MUC5B MUC5AC

2.60e-052178211587997
Pubmed

MTHFR and MTRR gene polymorphisms in patients with chronic hepatitis B virus infections in Zigong, Sichuan Province.

MTHFR MTRR

2.60e-052178238634541
Pubmed

Productive recognition of factor IX by factor XIa exosites requires disulfide linkage between heavy and light chains of factor XIa.

F9 F11

2.60e-052178222207756
Pubmed

Methylenetetrahydrofolate reductase (MTHFR) 677C>T and methionine synthase reductase (MTRR) 66A>G polymorphisms: association with serum homocysteine and angiographic coronary artery disease in the era of flour products fortified with folic acid.

MTHFR MTRR

2.60e-052178212801615
Pubmed

5-Fluorouracil-based chemotherapy for colorectal cancer and MTHFR/MTRR genotypes.

MTHFR MTRR

2.60e-052178221204909
Pubmed

Maternal gene polymorphisms involved in folate metabolism and risk of Down syndrome offspring: a meta-analysis.

MTHFR MTRR

2.60e-052178217934692
Pubmed

Association of Methylenetetrahydrofolate Reductase rs1801133 Gene Polymorphism with Cancer Risk and Septin 9 Methylation in Patients with Colorectal Cancer.

SEPTIN9 MTHFR

2.60e-052178238252186
Pubmed

Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.

MUC5B MUC5AC

2.60e-052178234656442
Pubmed

[Association of MTHFR and MTRR genes polymorphisms with non-disjunctions of chromosomes 18 and 21].

MTHFR MTRR

2.60e-052178226037359
Pubmed

Association of MTHFR (C677T, A1298C) and MTRR A66G polymorphisms with fatty acids profile and risk of neural tube defects.

MTHFR MTRR

2.60e-052178238716581
Pubmed

Maternal polymorphisms for methyltetrahydrofolate reductase and methionine synthetase reductase and risk of children with Down syndrome.

MTHFR MTRR

2.60e-052178219254790
Pubmed

Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.

MUC5B MUC5AC

2.60e-052178234058148
Pubmed

Additive Interaction of MTHFR C677T and MTRR A66G Polymorphisms with Being Overweight/Obesity on the Risk of Type 2 Diabetes.

MTHFR MTRR

2.60e-052178227983710
Pubmed

Structural characterization and expression studies of Dby and its homologs in the mouse.

DDX3X DDX3Y

2.60e-052178216728723
Pubmed

The interaction of factor XIa with activated platelets but not endothelial cells promotes the activation of factor IX in the consolidation phase of blood coagulation.

F9 F11

2.60e-052178212167623
Pubmed

Effects of single-nucleotide polymorphisms in MTHFR and MTRR on mortality and allograft loss in kidney transplant recipients.

MTHFR MTRR

2.60e-052178216316363
Pubmed

Cell adaptation to activated FGFR3 includes Sprouty4 up regulation to inhibit the receptor-mediated ERKs activation from the endoplasmic reticulum.

SPRY4 FGFR3

2.60e-052178219761767
Pubmed

Parental Genetic Variants, MTHFR 677C>T and MTRR 66A>G, Associated Differently with Fetal Congenital Heart Defect.

MTHFR MTRR

2.60e-052178228758112
Pubmed

PABPN1 functions as a hub in the assembly of nuclear poly(A) domains that are essential for mouse oocyte development.

PABPN1L PABPN1

2.60e-052178236306357
Pubmed

[Methylenetetrahydrofolate reductase and methionine synthase reductase gene polymorphisms in ethnic Han women from Linyi].

MTHFR MTRR

2.60e-052178223225055
Pubmed

Association between premature ovarian failure, polymorphisms in MTHFR and MTRR genes and serum homocysteine concentration.

MTHFR MTRR

2.60e-052178226874989
Pubmed

Associations of variants in MTHFR and MTRR genes with male infertility in the Jordanian population.

MTHFR MTRR

2.60e-052178224334125
Pubmed

[Geographical distribution characteristics of one carbon metabolic pathway related single nucleotide polymorphisms].

MTHFR MTRR

2.60e-052178232290927
Pubmed

Human skeletal muscle-specific alpha-actinin-2 and -3 isoforms form homodimers and heterodimers in vitro and in vivo.

ACTN2 ACTN3

2.60e-05217829675099
Pubmed

C-Mannosylation of MUC5AC and MUC5B Cys subdomains.

MUC5B MUC5AC

2.60e-052178214718370
Pubmed

Adenovirus binding to blood factors results in liver cell infection and hepatotoxicity.

F9 C4BPA

2.60e-052178215919903
Pubmed

Associations of homocysteine status and homocysteine metabolism enzyme polymorphisms with hypertension and dyslipidemia in a Chinese hypertensive population.

MTHFR MTRR

2.60e-052178230786773
Pubmed

Association of three missense mutations in the homocysteine-related MTHFR and MTRR gene with risk of polycystic ovary syndrome in Southern Chinese women.

MTHFR MTRR

2.60e-052178233407572
Pubmed

Different effects of maternal homocysteine concentration, MTHFR and MTRR genetic polymorphisms on the occurrence of fetal aneuploidy.

MTHFR MTRR

2.60e-052178236210274
Pubmed

Association of polymorphisms in one-carbon metabolizing genes with breast cancer risk in Syrian women.

MTHFR MTRR

2.60e-052178222373582
Pubmed

[Association of folate metabolism genes MTRR and MTHFR with complex congenital abnormalities among Chinese population in Shanxi Province, China].

MTHFR MTRR

2.60e-052178225140779
Pubmed

Mucin production during prenatal and postnatal murine lung development.

MUC5B MUC5AC

2.60e-052178221653907
Cytoband13q14

SPRYD7 TNFSF11 TRIM13

9.59e-0523178313q14
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

PAMR1 CSMD2 F13B HP C4BPA CSMD1

3.16e-065712961179
GeneFamilyWD repeat domain containing

STXBP5L COP1 ARPC1B WDR19 PWP1 DAW1 WDR41 WDR1 BUB3

1.11e-042621299362
GeneFamilyActinins

ACTN2 ACTN3

3.00e-04412921112
GeneFamilyCD molecules|Mucins

MUC19 MUC5B MUC5AC

4.30e-04211293648
GeneFamilyArgonaute/PIWI family

AGO4 AGO3

1.38e-0381292408
GeneFamilyPlexins

PLXNC1 PLXNB3

1.76e-0391292683
GeneFamilyBasic leucine zipper proteins|BTB domain containing

LZTR1 KLHL32 ABTB1 KLHL8 KLHL17

2.74e-031341295861
GeneFamilyExosome complex

DIS3L EXOSC7

3.18e-03121292817
GeneFamilyKelch like|BTB domain containing

KLHL32 KLHL8 KLHL17

3.32e-03421293617
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP10 ARHGAP17 ARHGAP33

5.45e-03501293721
GeneFamilyFibronectin type III domain containing

KALRN FNDC3A DSCAML1 ASTN2 EPHA8

5.82e-031601295555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

HSPG2 KALRN DSCAML1 NPTN FGFR3

5.97e-031611295593
ToppCellfacs-Brain_Non-Myeloid-Hippocampus|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO4 PSAT1 TRIM35 DDB1 ANKRD11 DDX3Y WDR1 MAP4K4 PLXNB3

1.19e-072001789fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCell15-Trachea-Epithelial-Secretory_progenitor|Trachea / Age, Tissue, Lineage and Cell class

FLNA EFEMP2 MXRA8 MUC5B SPRY4 LRRTM4 C4BPA FGFR3

8.95e-071871788be9fce9e74b2f170a2067f1b31d802912a578329
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNA KALRN ARHGAP10 ACTN2 HIF3A DYSF NECAB1 PLCL1

1.37e-061981788c12e7511628db819a52959bb68580e27c00c2e41
ToppCellSevere-B_intermediate-6|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FLNA IFT57 ARHGAP17 ARPC1B ST3GAL5 PLXNC1 SSBP4 MAP4K4

1.43e-061991788bf6ebb63ab361d9d1946225894d7be433e9befab
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

GPR137 MXRA8 ZNF248 PLXNC1 MTHFR GM2A PRKN

2.25e-06148178710dcbdb47cac908648d9d652c8095b536db19b8a
ToppCellfacs-Heart-RA-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJV ACTN2 HP DHRS7C GMPR TREX2 ALAS2

3.33e-0615717879021900d9b1a71210c9c414a9d165eaf399eb607
ToppCellfacs-Heart-RA-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJV ACTN2 HP DHRS7C GMPR TREX2 ALAS2

3.33e-061571787c8c627ca181856cd31dba4cf073c2be659a49dc1
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_early_2|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

ANO4 PAMR1 DAW1 GMPR MARVELD2 DYNLT4 FRMD3

7.07e-0617617878e0ac3ad5e47614b4befabd674a40e3eaae553f3
ToppCell(05)_Ciliated-(4)_1wkpi|(05)_Ciliated / shred by cell type and Timepoint

ARPC1B AGO4 HP DYNLT4 DCBLD2 PLXNB3 HDC

8.18e-06180178785fc9b164147b28545e2397d32302eea03ef6346
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 TNFAIP8L1 DYSF TAMALIN CD93 SPRY4 PLCL1

9.12e-061831787dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 TNFAIP8L1 DYSF TAMALIN CD93 SPRY4 PLCL1

9.12e-0618317874759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN STXBP5L LAMA1 MUC5B DSCAML1 FAT1 CSMD1

9.45e-0618417872cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN STXBP5L LAMA1 MUC5B DSCAML1 FAT1 CSMD1

9.45e-0618417872b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN STXBP5L LAMA1 MUC5B DSCAML1 FAT1 CSMD1

9.45e-061841787ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DENND5B HSPG2 TSHR TAMALIN PLXNC1 PLCL1 ST8SIA4

9.78e-061851787fec16a5e527fdef32d25957451b6e8ee9796cafd
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KALRN ARHGAP10 DPYSL5 CSMD2 FAT1 PLCL1 CSMD1

1.01e-0518617874780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 NPR1 CD93 AGO3 PLXNC1 SPRY4 GMPR

1.25e-051921787d525f7f088a53110912600a7c9f6d33b9270d534
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 NPR1 CD93 AGO3 PLXNC1 SPRY4 GMPR

1.25e-0519217872bfac6b3956265205ca47d06888851ed68b65999
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFT57 TNFAIP8L1 MUC5B LRRIQ1 DAW1 VWA3B DYNLT4

1.25e-0519217876c269d2426f76559d2ed3bf2169eb4be5fc7ad6d
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 NPR1 MXRA8 CD93 PLXNC1 SPRY4 GMPR

1.29e-051931787d5f6d6e2c36d4e80af4d39cdfc0b18df295a587b
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 NPR1 MXRA8 CD93 PLXNC1 SPRY4 GMPR

1.29e-0519317874a8c97ff2dffc5c06351d1cb107e21e58250aa55
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNFAIP8L1 MUC5B LRRIQ1 DAW1 VWA3B DYNLT4 MUC5AC

1.38e-0519517879651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell10x_3'_v3-blood_(10x_3'_v3)|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DYSF ARPC1B AGO4 PLXNC1 ABTB1 GMPR ALAS2

1.47e-0519717872d3547107c88c7443fc6425742694e13368a71f5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 KALRN HIF3A DYSF TAMALIN CD93 MAP4K4

1.47e-051971787cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 KALRN HIF3A DYSF TAMALIN CD93 MAP4K4

1.47e-051971787412cb5f37df57121ddd1492021445479c7cbccbf
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ANO4 FLNA PPP1R12A FAT1 NECAB1 NT5DC2 SPRY4

1.57e-051991787aacd3ffa40a6e6f435aa9be5b959d88812eb69d4
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAT1 TRIM35 SIRT2 DDX3Y WDR1 MAP4K4 PLXNB3

1.62e-052001787f0c338877e39226a90c4effe12f6501d33542a73
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

ARHGAP10 STXBP5L PARP8 CSMD2 SPRY4 LRRTM4 CSMD1

1.62e-052001787961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

ARHGAP10 STXBP5L PARP8 CSMD2 SPRY4 LRRTM4 CSMD1

1.62e-052001787f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

ARHGAP10 STXBP5L PARP8 CSMD2 SPRY4 LRRTM4 CSMD1

1.62e-052001787cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

ARHGAP10 STXBP5L PARP8 CSMD2 SPRY4 LRRTM4 CSMD1

1.62e-052001787c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

ARHGAP10 STXBP5L PARP8 CSMD2 SPRY4 LRRTM4 CSMD1

1.62e-0520017874fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

ARHGAP10 STXBP5L PARP8 CSMD2 SPRY4 LRRTM4 CSMD1

1.62e-052001787310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)--|Thalamus / BrainAtlas - Mouse McCarroll V32

ZFAND2B HIF3A DYSF TMEM71 VWA3B MARVELD2

2.31e-0514217865fd737c1fee9d97aee8955f1bf378ead3fce138d
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)-|Thalamus / BrainAtlas - Mouse McCarroll V32

ZFAND2B HIF3A DYSF TMEM71 VWA3B MARVELD2

2.31e-05142178616f9945e835c3506b12d904778560d065a50f059
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)|Thalamus / BrainAtlas - Mouse McCarroll V32

ZFAND2B HIF3A DYSF TMEM71 VWA3B MARVELD2

2.31e-05142178658bfff3284ae21150e4619511bd58622c16c5dde
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NID2 PSAT1 KCNH1 ALAS2 PLCL1 ARHGAP33

3.51e-051531786489228ab81c3ae339a53a9da6c2a1c1b6ac3f84b
ToppCellfacs-Brain_Myeloid-Cortex_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEPTIN9 TNFAIP8L1 CD93 HP PLXNC1 ADGRE4P

3.92e-0515617862ba838bc864c2c1767bcab7bb4d790af96b91387
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-FB-1|E18.5-samps / Age Group, Lineage, Cell class and subclass

ANO4 MXRA8 AMIGO3 PLXNC1 DDX3Y ALAS2

4.36e-051591786b4bc888e978b1b577721b891b0af6ba9a1607044
ToppCellfacs-Lung-Endomucin-24m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA TIFAB ARPC1B HP ADGRE4P GM2A

4.36e-051591786886cbaef39a3517514a3896b6b960d01a3af043d
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNA TIFAB ARPC1B HP ADGRE4P GM2A

5.36e-0516517861d844d19ff9b49dd0f61f0b24799e172076771ef
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNA TIFAB ARPC1B HP ADGRE4P GM2A

5.36e-0516517869a6abd0e6b11860231ce5e845c87b8d66f3ef697
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNA TIFAB ARPC1B HP ADGRE4P GM2A

5.36e-051651786433771abefc5bcb89bdae64af45cce7407bffe5d
ToppCellfacs-Heart-LA-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJV LAMA1 ACTN2 KLHL32 DHRS7C EPHA8

5.54e-051661786829a8998ce68739a58202851afd73e049ab0f84f
ToppCellfacs-Heart-LA-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJV LAMA1 ACTN2 KLHL32 DHRS7C EPHA8

5.54e-051661786c43aec09578975df8984886993d15b42a10190c8
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-neuroepithelial-like_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

LZTR1 PDE6B HTATIP2 ARHGAP17 ACTN2 ZFP2

5.73e-051671786e488d9c7cf4355959e3833de3bd496c13fc11b1b
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Tfr.Tmem2_(Tmem2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KIF24 SIRT2 FCGBP MAP4K4 PLXNB3

5.86e-051031785287e945ef2f9646f1ff4a4c50fe6e8a5e7fe0d92
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA TIFAB SEPTIN9 TBC1D2B HP ADGRE4P

5.92e-051681786c0aef5947b1d7e2c81a7481c509feda1687fcd7f
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA TIFAB SEPTIN9 TBC1D2B HP ADGRE4P

5.92e-051681786c861f80aa12caf54a94d93e38539ff41dc5227a6
ToppCelldroplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA TIFAB ST3GAL5 HP ADGRE4P GM2A

6.12e-051691786b059304543876f514d5c7214f1f0a2da00f10a67
ToppCelldroplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA TIFAB ST3GAL5 HP ADGRE4P GM2A

6.12e-051691786945f737984c4de70a4e9c214053b005358053dd5
ToppCelldroplet-Spleen-nan-21m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIFAB LAMA1 CD93 FCGBP HP ADGRE4P

6.32e-05170178603cb4e508356f85372a588c8d1c6babf2a012683
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D2B PABPN1L PKD1L3 FCGBP ADGRE4P CSMD1

6.32e-051701786a121e10099faaeb60251eec162f38caf7c4238c2
ToppCelldroplet-Spleen-nan-21m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIFAB LAMA1 CD93 FCGBP HP ADGRE4P

6.53e-0517117869498c35b2a2c3a339dc8c5d49c8ec20d8ad52753
ToppCelldroplet-Spleen-nan-21m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIFAB LAMA1 CD93 FCGBP HP ADGRE4P

6.53e-051711786db544252f98e073e5bb4bec4a110cd58e6434435
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRIM35 TBC1D2B CENPU PKD1L3 TAMALIN NXF3

6.74e-05172178694093d356b0252b440deda4e1b0ac332b31513f6
ToppCelldroplet-Spleen-SPLEEN-30m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST3GAL5 HP NT5DC2 DDX3Y ALAS2 HDC

6.74e-05172178602cc4a9fb7902c572cee37ba828749db4913ee87
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 PSAT1 TMEM71 ARPC1B LRRTM4 PLXNB3

6.96e-051731786789ab8b2709f4b8728e3733bc72744e9d92ea5ea
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND5B MUC5B PABPN1L PKD1L3 F9 CHPF2

7.19e-0517417863f4277763e312b46ebd4401ea4a2f5d4c850c768
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT3 LAMA1 FCGBP HP FGFR3 BBOX1

7.19e-051741786a0ccda8fd6f55251cdeff24cf66e72e4a31d2104
ToppCelldroplet-Bladder-Unstain-18m-Hematologic-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTN2 TNFSF11 ST3GAL5 PLXNC1 PLXNB3 HDC

7.19e-051741786773329bb91b97578df138446cf62101dd0dad758
ToppCelldroplet-Lung-nan-21m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND5B MUC5B PABPN1L PKD1L3 F9 CHPF2

7.19e-051741786fad66d1a8407574b6a835e0bdb824a53afa58650
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D2B PABPN1L PKD1L3 FCGBP ADGRE4P CSMD1

7.42e-051751786f7cd2ef79d91d64976fcdb5f1e7343b24ba27456
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DENND5B PSAT1 TSHR SAMD7 AMIGO3 NT5DC2

7.42e-0517517863b5346fba617292de71963b6175e85a4f182fe30
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DENND5B PSAT1 TSHR SAMD7 AMIGO3 NT5DC2

7.66e-051761786dc4e939a07bad21ab36181f9588df3fa662f9a92
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4|TCGA-Lung / Sample_Type by Project: Shred V9

RNF213 DYSF THBS2 PLXNC1 ST8SIA4 DCBLD2

7.66e-0517617860923b01137d6f9956ca815b41102c81e82624065
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

KALRN RNF213 DENND1A CD93 URB1 AGO3

7.90e-05177178682fdd6185b368f54f03de389427cbe3071d21a99
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBC1D2B DENND1A THBS2 PLXNC1 ASTN2 DCBLD2

8.15e-051781786c87945146b2734141f07b39d268e0d8086ee0364
ToppCelldroplet-Lung-1m-Hematologic-myeloid|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA TIFAB SEPTIN9 ARPC1B HP GM2A

8.40e-0517917866d2458a887047b5c20389f08345ff5aac7c683e6
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RB HTATIP2 TAMALIN ARPC1B CD93 SSBP4

8.66e-0518017862405aa5699a8d8cf4c6b3dca07510e774728ac50
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RB HTATIP2 TAMALIN ARPC1B CD93 SSBP4

8.66e-0518017869c47852c0a723e2f5cd6898afff4c31a0da06905
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RB HTATIP2 TAMALIN ARPC1B CD93 SSBP4

8.66e-051801786499d5fe71e0dc20cffdf85e3b3f14eb4e83e3a3d
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 PSAT1 CSMD1 ZFP2 PLXNB3 FRMD3

9.21e-051821786a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMK+-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

PARP8 RNF213 TIGIT PDZD8 DDX3Y EPHA8

9.49e-05183178679defd22b3194dad16db55b9bdd220c09c1e6b90
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC19 DYSF LRRIQ1 HP ABTB1 C4BPA

9.78e-0518417867ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCellwk_15-18-Hematologic-Myeloid-MEP|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CENPU PLXNC1 NXF3 PDZD8 GMPR HDC

9.78e-05184178619d61d0ab038b7e729e13a46f88b8cf31759485d
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DENND5B TSHR TAMALIN PLXNC1 PLCL1 ST8SIA4

9.78e-0518417860a26bcc6610f756939e32a4d6dfeebcbf3a1db86
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 MXRA8 AGO3 PLXNC1 SPRY4 HDC

1.01e-041851786742350093d90f96735dc73e3360cdd749bae63fd
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPA1 FCGBP DDX3Y GMPR FGFR3 DCBLD2

1.01e-041851786e29079ef09aee62c3e9756341db4e59ca9dbf7ac
ToppCellfacs-Large_Intestine-Distal-24m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPA1 FCGBP DDX3Y GMPR FGFR3 DCBLD2

1.01e-0418517862ecc4b76b3645b65c226c2298bff307cc6479172
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO4 NID2 NPR1 PAMR1 CD93 GMPR

1.04e-04186178602418c50fdcca549bf73dedf6199ab4a27862a9b
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO4 NID2 NPR1 PAMR1 CD93 GMPR

1.04e-04186178639e475a3c167b33daa63b0c1bfa32451c5f46635
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAMR1 LAMA1 HIF3A FGFR3 BBOX1 PLXNB3

1.04e-04186178641e03be964044dae690d566bd078dab3d8045eba
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP10 CSMD2 THBS2 FAT1 PLCL1 CSMD1

1.04e-041861786a95744b8649096bd7cfc3591a02841fa411085b3
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MXRA8 LAMA1 THBS2 AMIGO3 XXYLT1 ASTN2

1.07e-041871786b6ecf55014f246461bf1ca12f24cb4d046661fa4
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NID2 EFEMP2 THBS2 LRRTM4 FGFR3 BBOX1

1.07e-041871786f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCellControl-Myeloid-MoAM5|Control / Disease group,lineage and cell class (2021.01.30)

GALNT3 IFT57 TNFSF11 FCGBP SACS PLXNC1

1.07e-0418717868769341be67382cea2a590d962f4def7c39de883
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MXRA8 LAMA1 THBS2 AMIGO3 XXYLT1 ASTN2

1.07e-0418717869fb15f24b9b364b0c4704ec98aec236eaec5411c
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MXRA8 LAMA1 THBS2 AMIGO3 XXYLT1 ASTN2

1.07e-041871786e6afbaed352310a1cb49571a2aae18be1f533c9a
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HSPG2 NPR1 DYSF ARPC1B CD93 GMPR

1.07e-04187178603de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCellBAL-Control-Myeloid-MoAM-MoAM5-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GALNT3 IFT57 TNFSF11 FCGBP SACS PLXNC1

1.07e-0418717860d589de12108230ced5b60229564f4a181e2f172
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KALRN ARHGAP10 STXBP5L NECAB1 KCNH1 LRRTM4

1.07e-041871786f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCellBAL-Control-Myeloid-MoAM-MoAM5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GALNT3 IFT57 TNFSF11 FCGBP SACS PLXNC1

1.07e-04187178659d28f4ee1d463ae20abb8d7e7399b504d80698a
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NID2 EFEMP2 THBS2 LRRTM4 FGFR3 BBOX1

1.07e-04187178602e7246ef5ad41773d14426254e139b156d45c1d
ToppCellBAL-Control-Myeloid-MoAM-MoAM5-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GALNT3 IFT57 TNFSF11 FCGBP SACS PLXNC1

1.07e-04187178625adf648c05c21534b4913254e73d43fc5f64e06
ToppCellBAL-Control-Myeloid-MoAM-MoAM5|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

GALNT3 IFT57 TNFSF11 FCGBP SACS PLXNC1

1.07e-0418717863b0cfa9e5ea5e7d6dda689c328b9b5110b43ee1d
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D175|Adult / Lineage, Cell type, age group and donor

HIF3A DYSF TAMALIN CD93 FAT1 NXF3

1.07e-041871786f3548817f2fded5978137bb252cb628ac199e4f6
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NID2 EFEMP2 THBS2 LRRTM4 FGFR3 BBOX1

1.07e-04187178608c73d125e0638c9e9878165bba2442c266c8a48
ToppCellP07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NPR1 TAMALIN ARPC1B CD93 FGFR3 FRMD3

1.10e-0418817865bc1537e079c7435196c163bff5f639ea392a33a
ToppCellControl-B_intermediate-6|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FLNA RNF213 ARPC1B ST3GAL5 SACS PLXNC1

1.13e-04189178611cb9a16f1de8f60af2073ed7ea6d4f41c02f299
Diseaseanorectal malformation

MUC5B CSMD2 THBS2 KLHL17

3.94e-06191714MONDO_0019938
Diseasechildhood medulloblastoma (implicated_via_orthology)

DDX3X DDX3Y

3.34e-0521712DOID:3869 (implicated_via_orthology)
DiseaseThyrotoxicosis

TSHR MTHFR

3.34e-0521712C0040156
Diseasethanatophoric dysplasia (implicated_via_orthology)

HSPG2 FGFR3

3.34e-0521712DOID:13481 (implicated_via_orthology)
DiseaseEpilepsy

FLNA DDX3X KCNH1 ANKRD11 RARS2 FGFR3

4.29e-051091716C0014544
DiseaseColorectal Carcinoma

KALRN PARP8 LAMA1 CUBN DSCAML1 CD93 FAT1 SACS MTHFR MTRR FGFR3 ST8SIA4 CAMSAP2 HDC

6.42e-0570217114C0009402
DiseaseDiabetic Angiopathies

THBS2 HP MTHFR

1.01e-04161713C0011875
DiseaseMicroangiopathy, Diabetic

THBS2 HP MTHFR

1.01e-04161713C0025945
DiseaseMalignant neoplasm of breast

IL24 NID2 FLNA TFAP2D KALRN CUBN DYSF UBLCP1 DDX3X NOP9 HP KCNH1 MTHFR DAW1 ANKRD30A ASTN2 HNRNPR

1.79e-04107417117C0006142
DiseaseNeural tube defects, folate-sensitive

MTHFR MTRR

1.99e-0441712cv:C1866558
Diseasemethylmalonate (MMA) measurement

ANKRD11 ZNF778

1.99e-0441712EFO_0800622
DiseaseSertoli cell-only syndrome (implicated_via_orthology)

DDX3X DDX3Y

1.99e-0441712DOID:0050457 (implicated_via_orthology)
DiseaseNeural tube defect, folate-sensitive

MTHFR MTRR

1.99e-0441712C1866558
DiseaseNEURAL TUBE DEFECTS, FOLATE-SENSITIVE

MTHFR MTRR

1.99e-0441712601634
Diseasehepatocellular adenoma (biomarker_via_orthology)

CARM1 HP

3.30e-0451712DOID:0050868 (biomarker_via_orthology)
Diseasefocal segmental glomerulosclerosis 1 (implicated_via_orthology)

ACTN2 ACTN3

3.30e-0451712DOID:0111128 (implicated_via_orthology)
DiseaseAffective Disorders, Psychotic

HP MTHFR

3.30e-0451712C0001723
Diseasevenous thromboembolism

PSAT1 GRK4 DPYSL5 F9 F11 CD93 LRRTM4 ASTN2 C4BPA ST8SIA4

3.73e-0446017110EFO_0004286
Diseasehemochromatosis (is_implicated_in)

HJV ALAS2

4.93e-0461712DOID:2352 (is_implicated_in)
DiseaseCarcinoma in situ of uterine cervix

MTHFR FGFR3

4.93e-0461712C0851140
Diseasespina bifida (is_implicated_in)

MTHFR MTRR

4.93e-0461712DOID:0080016 (is_implicated_in)
Diseaseoral squamous cell carcinoma (is_implicated_in)

FAT1 MTHFR FGFR3

5.63e-04281713DOID:0050866 (is_implicated_in)
DiseaseDevelopmental regression

ADPRS ST3GAL5

6.88e-0471712C1836830
Diseasecoronary aneurysm

TIFAB CSMD2 CSMD1

1.09e-03351713EFO_1000881
Diseasemitral valve prolapse (is_implicated_in)

FLNA TSHR

1.17e-0391712DOID:988 (is_implicated_in)
Diseasemacrophage colony stimulating factor measurement

MTRR CSMD1 EPHA8

1.29e-03371713EFO_0008217
DiseaseEpilepsy, Cryptogenic

FLNA DDX3X KCNH1 ANKRD11

1.34e-03821714C0086237
DiseaseAwakening Epilepsy

FLNA DDX3X KCNH1 ANKRD11

1.34e-03821714C0751111
DiseaseAura

FLNA DDX3X KCNH1 ANKRD11

1.34e-03821714C0236018
Diseasevenous thromboembolism, factor VII measurement

F11 XXYLT1 C4BPA

1.39e-03381713EFO_0004286, EFO_0004619
Diseasepolymeric immunoglobulin receptor measurement

IL24 CHPF2

1.46e-03101712EFO_0008267
DiseaseGiant Cell Glioblastoma

LZTR1 FAT1 PRKN FGFR3

1.46e-03841714C0334588
DiseaseHyperhomocysteinemia

MTHFR MTRR

1.77e-03111712C0598608
Diseasepulmonary fibrosis

MUC5B MUC5AC

1.77e-03111712EFO_0009448
Diseasecraniosynostosis (is_implicated_in)

FLNA FGFR3

2.12e-03121712DOID:2340 (is_implicated_in)
Diseasetriacylglycerol 44:1 measurement

PRKN CSMD1

2.12e-03121712EFO_0010399
DiseaseHereditary hemochromatosis

HJV HP

2.12e-03121712C0392514
DiseaseHemochromatosis

HJV HP

2.12e-03121712C0018995
Diseasealbuminuria

TSHR CUBN CSMD1 STEAP1B

2.21e-03941714EFO_0004285
Diseasehomocysteine measurement

CUBN MTHFR CSMD1

2.42e-03461713EFO_0004578
Diseasecystatin C measurement

TFAP2D KALRN SEPTIN9 FNDC3A CD93 ANKRD11 SLX4IP ZNF778

2.48e-034021718EFO_0004617
Diseaseillegal drug consumption

SEPTIN9 CSMD1

2.50e-03131712EFO_0005431
Diseaserhinitis (biomarker_via_orthology)

MUC5AC HDC

2.50e-03131712DOID:4483 (biomarker_via_orthology)
Diseasehypoxanthine mesurement

XXYLT1 GMPR

2.90e-03141712EFO_0010500
Diseasetotal brain volume change measurement

LRRTM4 WDR41

2.90e-03141712EFO_0021504
Diseaseresponse to 5-fluorouracil, response to cyclophosphamide, chemotherapy-induced alopecia, response to doxorubicin

DENND1A CSMD1

2.90e-03141712EFO_0005400, GO_0036275, GO_1902518, GO_1902520
DiseaseHypermetropia

ARHGAP10 SEPTIN9 DSCAML1 ANKRD11

3.08e-031031714HP_0000540
Diseaseresponse to cisplatin, platinum measurement

EFEMP2 DYSF CSMD1

3.62e-03531713EFO_0010154, GO_0072718
DiseaseSpondyloepiphyseal Dysplasia

HSPG2 FLNA

3.80e-03161712C0038015
DiseaseSpondyloepiphyseal Dysplasia Tarda, X-Linked

HSPG2 FLNA

3.80e-03161712C3541456
Diseaseamygdala volume change measurement

PARP8 CSMD1

3.80e-03161712EFO_0021490
Diseaseosteosarcoma (is_implicated_in)

EFEMP2 MTHFR

3.80e-03161712DOID:3347 (is_implicated_in)
DiseaseSchwartz-Jampel Syndrome, Type 1

HSPG2 FLNA

3.80e-03161712C4551479
Diseasegliosarcoma

LZTR1 FGFR3

3.80e-03161712C0206726
DiseaseSchwartz-Jampel Syndrome

HSPG2 FLNA

3.80e-03161712C0036391
DiseaseMelnick-Needles Syndrome

HSPG2 FLNA

3.80e-03161712C0025237
DiseaseAutistic Disorder

LZTR1 FMR1 COP1 MTHFR ASTN2 PRKN

4.27e-032611716C0004352
DiseaseVan Buchem disease

HSPG2 FLNA

4.29e-03171712C0432272
Diseasegraft-versus-host disease (is_implicated_in)

IL10RB MTHFR

4.29e-03171712DOID:0081267 (is_implicated_in)
DiseaseIntellectual Disability

FMR1 PPP1R12A LAMA1 DDX3X ADPRS ST3GAL5 SACS HNRNPR

4.70e-034471718C3714756
Diseaseneuroblastoma

KALRN PARP8 KLHL8 CSMD1

4.71e-031161714EFO_0000621
Diseaseadverse effect, response to xenobiotic stimulus

LAMA1 ASTN2 VWA3B

4.90e-03591713EFO_0009658, GO_0009410
Diseaseresponse to methotrexate, juvenile idiopathic arthritis

ANO4 CSMD1

5.35e-03191712EFO_0002609, GO_0031427
Diseaseosteochondrodysplasia (is_implicated_in)

HSPG2 FLNA

5.35e-03191712DOID:2256 (is_implicated_in)
DiseaseOsteochondrodysplasias

HSPG2 FLNA

5.35e-03191712C0029422
DiseaseDyschondroplasias

HSPG2 FLNA

5.35e-03191712C0013366
Diseasecolorectal cancer (is_implicated_in)

SEPTIN9 DDX3X FAT1 FGFR3

5.47e-031211714DOID:9256 (is_implicated_in)
Diseasevital capacity

HSPG2 SEPTIN9 ACTN3 GMPR2 PKD1L3 THBS2 LRRIQ1 LRRTM4 GSTCD SLX4IP GM2A ASTN2 PLCL1 WDR41 SSBP4

5.68e-03123617115EFO_0004312

Protein segments in the cluster

PeptideGeneStartEntry
YGDEISFSCHETSRF

C4BPA

391

P04003
SIEFDRDCDYFAIAG

COP1

426

Q8NHY2
ESRSFSYIEFHCGVD

EDDM3A

116

Q14507
YGGSAEELEAHFSRC

PABPN1L

156

A6NDY0
CFYHAFAGAEQAETA

ACTN2

251

P35609
DYADLVFDCADSQHS

ANKRD11

1731

Q6UB99
SYFVGALIVHADCFL

ARSL

241

P51690
DEGHFTDTVVLYSCN

CSMD1

1231

Q96PZ7
FTLDSKVVYECHEGF

CSMD1

2511

Q96PZ7
YHLQAGAEATAECLD

CSMD2

2561

Q7Z408
TVGYRVATFHDCEDA

DPM3

56

Q9P2X0
SAEEALQHPYFSDFC

CDK5

276

Q00535
DLEYHDTCSFDFLEI

CDCP2

76

Q5VXM1
CSETYHGKFANSEVE

CPA1

271

P15085
AGHDCFPVLFTYDAA

ARPC1B

261

O15143
GRTYFHDSSEKCEDI

ADGRE4P

41

Q86SQ3
SFHCSCEEGYVLAGE

CD93

406

Q9NPY3
VFAADICGVTAEHYA

ANKRD30A

231

Q9BXX3
YADEEEFSKHCGLSL

CENPU

81

Q71F23
TGAVLDCAFYDPTHA

BUB3

56

O43684
EFDFYLCSHAGIQGT

AGO3

746

Q9H9G7
SEFDFYLCSHAGIQG

AGO4

746

Q9HCK5
HLYLGCNELASFSFD

AMIGO3

161

Q86WK7
DSCVYAKVTHLFDNG

ANO4

411

Q32M45
AGLCGEDYVFFHLDI

NPR1

261

P16066
AEALYGSELTCIIHF

ASTN2

906

O75129
EALHLARDFGYTCET

TFAP2D

296

Q7Z6R9
FAECHALVDSTAYLA

MUC5B

271

Q9HC84
EAEFACHSYNECVAL

HSPG2

201

P98160
AYFHSCVFDVLISGD

HJV

356

Q6ZVN8
VYPCEAEHSSELSFE

ARHGAP10

736

A1A4S6
HIDAAYAGTAFLCPE

HDC

271

P19113
SLEDFLYHEGYACTS

DDX3X

456

O00571
GHFVTCVKAYDADSS

FAT1

2406

Q14517
SAYHDEACFSLSIPF

NXF3

366

Q9H4D5
VIYGSCAGFHAVDVD

MAP4K4

1086

O95819
CAGFHAVDVDSGSVY

MAP4K4

1091

O95819
HIRSEFGDYFDICVA

MTHFR

181

P42898
CDDFLVYCGDTHGSF

NOP9

191

Q86U38
TDHVCTRFFFVYEDG

PARP8

811

Q8N3A8
PSVDFDHSCSDSVEY

LZTR1

26

Q8N653
DDYASAFQGHDVGFC

HTATIP2

76

Q9BUP3
CYGDAGSAFAVHDLE

HP

351

P00738
YCESHAFADIPENIS

LRRTM4

46

Q86VH4
LAAGLHDACYSSDEA

DYNLT4

131

Q5JR98
ASRSYFFDRAGHCED

GPR137

316

Q96N19
FSADLHCISESDKYD

MTRR

31

Q9UBK8
SAGIALYSHEDVCVF

CARM1

66

Q86X55
RGFCFLEYEDHKTAA

SYNCRIP

286

O60506
GSSVEYRCFDHHFLE

F13B

546

P05160
ACTFDDTSEGAVHYF

PCNX3

651

Q9H6A9
HCAFGDYDSLAHVEG

PLXNB3

561

Q9ULL4
IANFTSDVEYSDDHC

PLXNC1

1306

O60486
YACDHFTEVVECEDF

KLHL8

191

Q9P2G9
SLEAEDAAAYYCHQS

IGKV6D-21

96

A0A0A0MT36
SFLEDYCGHENGTFR

MUC19

1301

Q7Z5P9
FGSYDREANVHCTLE

PDZD8

336

Q8NEN9
ECPHFSSFADELTDY

PDE6B

156

P35913
YSATLAGDHCFDVLD

PCED1A

216

Q9H1Q7
GYLLSAECTVFLDHE

F9

21

P00740
FCFLEYEDHKSAAQA

HNRNPR

291

O43390
HEYFCGVSNAARDFI

KALRN

2901

O60229
GHDDEILDSCFDYTG

DAW1

301

Q8N136
QHVFYFDEVFGEACT

KIF24

271

Q5T7B8
DLIYHAGESVDSLCF

KCNH1

606

O95259
ICLDVANGYSEHFVE

GMPR2

126

Q9P2T1
EFVADETERAYSFCG

RPS6KA5

201

O75582
VFSEHCGAAYEDFNI

MUC5AC

106

P98088
YFLCHLALVDAGFTT

OR2I1P

61

Q8NGU4
EGYLEFFVDCSASAT

EXOSC7

76

Q15024
ARGDADDAVYHTCFF

TAMALIN

276

Q7Z6J2
DDAVYHTCFFGDSEP

TAMALIN

281

Q7Z6J2
EELCDVSHQYGALTF

ALAS2

341

P22557
GDVFTLDTAENLCHY

LRRIQ1

1186

Q96JM4
SGYEFADDRHTCILI

NID2

831

Q14112
YGATAEELEAHFHGC

PABPN1

181

Q86U42
LADCAHFHYENVDFG

ARHGAP33

46

O14559
FEIGSSAHCETDYVE

CUBN

861

O60494
IFHGRLLCSFSDAAY

FRMD3

136

A2A2Y4
TAIDLDEDTCTFHIY

FMR1

251

Q06787
GEHVCYVLDCFAEEA

IFT57

141

Q9NWB7
SLFAIHGDCEAYDTR

KLHL17

351

Q6TDP4
IHDNDYFCTAENAAG

DSCAML1

96

Q8TD84
DSVFFSCHAINSYGE

DSCAML1

861

Q8TD84
YVTLDGHRFDFQGTC

FCGBP

3281

Q9Y6R7
AHEPTYFTVDCAEAG

FLNA

786

P21333
ETLTFLDAHCECFYG

GALNT3

271

Q14435
CDHGSEILAYSIDFG

FNDC3A

886

Q9Y2H6
SCAEEEFHHYGLALD

DIS3L

776

Q8TF46
RHCGYSKAFQDSDEE

EPHA8

566

P29322
SDAESCYLVHTLLEF

IL24

101

Q13007
DIGVDYCDFSVQSKH

BBOX1

261

O75936
FAHYFVLCGIDADSG

DENND5B

21

Q6ZUT9
CHSSFYHDTDFLGEE

F11

291

P03951
LLGDCVGSFYEAHDT

ADPRS

31

Q9NX46
LTECDFSSLSKYGDH

IL10RB

71

Q08334
GVFACVTAYIHKDSE

MARVELD2

206

Q8N4S9
TFCEEAFVSHYRSGA

DENND1A

336

Q8TEH3
GDFDIEDSDSCHFNY

DCBLD2

116

Q96PD2
RAFEGVDCVFHVASY

SDR42E2

91

A6NKP2
TYAASKHAALGFFDC

DHRS7C

191

A6NNS2
LHNVTFEDAGEYTCL

FGFR3

326

P22607
ICLDVANGYSEHFVE

GMPR

126

P36959
EDFLYHEGYACTSIH

DDX3Y

456

O15523
DEDFYARFATGCVSI

GRK4

496

P32298
GYELHRDGFSCSDID

EFEMP2

231

O95967
LVHDDFSVICQGFYE

SACS

1951

Q9NZJ4
DTDISDAYCSAVFAG

DYSF

16

O75923
EEYLYLDFSHQTEGC

GSTCD

11

Q8NEC7
DGTDGCALAALIHFY

CAMSAP2

251

Q08AD1
FESSHYLLCALGDGA

DDB1

596

Q16531
ATCVDDFYHGTKAAL

DPYSL5

76

Q9BPU6
FDGFHAIYEEITACS

PAMR1

226

Q6UXH9
LLGAYHDEACFSLAI

NXF2

411

Q9GZY0
DYIGSCTFEHFCDVL

GM2A

101

P17900
HSLEETFGCGYLNDF

RARS2

471

Q5T160
IFYHCTNEDDEGSCA

SPRY4

206

Q9C004
EGELSFYDAERHCHL

TRIM35

436

Q9UPQ4
IFPSFTCDSLDGYHS

TMEM71

31

Q6P5X7
AYHEGECSAVFEASG

PRKN

371

O60260
GCSDYAQVFKDHAID

SAMD7

341

Q7Z3H4
GFGDSCKFLHDRSDY

RNF113B

206

Q8IZP6
AALDCSTSHLDEFYS

ARHGAP17

301

Q68EM7
GCSAYEYIHALDSDA

HIF3A

271

Q9Y2N7
FCSGLSHLCSELEDY

LAMA1

1151

P25391
YCANETVHGVEFDFI

PSAT1

151

Q9Y617
ICQTGDFLDGDAHYE

PKD1L3

136

Q7Z443
GTIEVENTTHCEFAY

SEPTIN9

521

Q9UHD8
NVSAYCLHIAEDDGE

MAPKAP1

226

Q9BPZ7
TLATRFCDEIHLYGF

ST8SIA4

286

Q92187
EDLVEAHGTFYTSHC

SIRT2

181

Q8IXJ6
HLCDEVSLAGFGYDL

ST3GAL5

351

Q9UNP4
ASICLHSDYAAALFE

WDR19

431

Q8NEZ3
AYSHDGAFLAVCDAS

WDR1

496

O75083
IFLCHLAFVDIGYSS

OR5P3

61

Q8WZ94
DDSAILDCQFSEFYH

SPRYD7

166

Q5W111
CESSHFAVLLGAYGA

URB1

1521

O60287
VKGLFYHCSTDDEDN

SPRY3

191

O43610
DIHESPVTCTAYFAD

STXBP5L

406

Q9Y2K9
TERVLHGVSDYFAEC

SLX4IP

136

Q5VYV7
HGVSDYFAECAESSL

SLX4IP

141

Q5VYV7
DYLQTAHADEFDCPS

STEAP1B

26

Q6NZ63
CGRSDYFRALLDDHF

ABTB1

291

Q969K4
VSCFYHAFAGAEQAE

ACTN3

256

Q08043
DYFTEQHTFSCADGA

CHPF2

376

Q9P2E5
CHFLASTDDGFVYNL

PWP1

356

Q13610
DVFIGYHSDACASVV

RNF213

3216

Q63HN8
EDCAFSILHGENYES

PLCL1

186

Q15111
ECGKAFTQSAYLFDH

ZNF197

626

O14709
TGDSCVSNHYERDFF

ZNF778

141

Q96MU6
ECGEAFSYSSAFRRH

ZNF555

316

Q8NEP9
GEHTKHVFCSIEDAY

TRIM13

121

O60858
LCSKHFQESDFESYG

THAP9

61

Q9H5L6
ESLLYHCLSDAEGDF

SPRED3

336

Q2MJR0
CEHSGEAKAFQDYSA

SSBP4

81

Q9BWG4
EDSGEYHCVYHFVSA

NPTN

211

Q9Y639
FRDCYFETHSVEDAG

TTC5

26

Q8N0Z6
VEEGTSLEAFVCYFH

TIFAB

116

Q6ZNK6
GEDCAELHDYFNVLS

TIGIT

216

Q495A1
LSCVVDYFLGHSLEF

NT5DC2

196

Q9H857
FGLYSGEEFHETFDC

VPS41

111

P49754
FHSSEYAYRCGIAEA

nan

466

Q3C1V9
YFVSIDAHAEECFFE

TMED2

21

Q15363
CFRHHETSGDLATEY

TNFSF11

221

O14788
YTLFDHRSCAETGVE

UBLCP1

146

Q8WVY7
HINSLELGDSAVYFC

TRBV3-1

96

A0A576
YDGFHRSFCDTDDLE

USP31

371

Q70CQ4
ECGKAFSQSAYLIEH

ZFP2

386

Q6ZN57
YSLHVGCDLIDSFAL

THBS2

161

P35442
LYDVLADCSFRHADG

VWA3B

406

Q502W6
DACSGIFCADHVAYA

ZFAND2B

26

Q8WV99
AHNGFDYDFPLLCAE

TREX2

116

Q9BQ50
SVYDAREFSVHFVCG

SLC25A19

111

Q9HC21
CFVEFYEHRDAAAAL

TIAL1

51

Q01085
ECDKAFIYGSQLSEH

ZNF571

506

Q7Z3V5
HLDIADACFSYQGPD

TBC1D2B

81

Q9UPU7
VFGHLADCDFLAALY

TNFAIP8L1

146

Q8WVP5
FLYFEDHGLVTCSAD

WDR41

411

Q9HAD4
EYGEIFCDNSAFIIH

ZNF248

301

Q8NDW4
SDVFEAYFRCEGHVK

XXYLT1

366

Q8NBI6
FDSHYDYTICGDSED

TSHR

381

P16473
SFDRSLSCHAGYVAD

KLHL32

431

Q96NJ5
AVEETDAGLYTCNLH

MXRA8

126

Q9BRK3
HAAASCGYLDIAEFL

PPP1R12A

111

O14974
DTEELCEYFSQHLGE

NECAB1

81

Q8N987