Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5B KDM5C KDM5D

5.39e-076613GO:0034647
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5B KDM5C KDM5D

1.50e-068613GO:0032453
GeneOntologyMolecularFunctionsemaphorin receptor activity

PLXNA4 PLXNA1 PLXNA2

5.85e-0612613GO:0017154
GeneOntologyMolecularFunctionzinc ion binding

CYLD RNF14 KDM5B TRAF2 USP22 MYCBP2 ZNF330 KDM5C FBXO43 ZSWIM1 ZSWIM7

7.09e-058916111GO:0008270
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM5B KDM5C KDM5D

8.42e-0528613GO:0141052
GeneOntologyMolecularFunctionhistone demethylase activity

KDM5B KDM5C KDM5D

1.15e-0431613GO:0032452
GeneOntologyMolecularFunctionprotein demethylase activity

KDM5B KDM5C KDM5D

1.26e-0432613GO:0140457
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC6A13 CLCN3 CLCN4 SLC17A1 SLC25A11

1.75e-04171615GO:0015103
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

AMHR2 OR5M10 OR2A7 OR2M7 OR5M1 PLXNA4 ADGRF4 ADGRF3 OR5AR1 PLXNA1 PLXNA2 TAAR6 OR10D4P

1.84e-0413536113GO:0004888
GeneOntologyMolecularFunctiontransition metal ion binding

CYLD RNF14 KDM5B TRAF2 USP22 MYCBP2 ZNF330 KDM5C FBXO43 ZSWIM1 ZSWIM7 OR5AR1

2.16e-0411896112GO:0046914
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A13 CLCN3 CLCN4 SLC17A1 SLC25A11 SLC39A14

2.82e-04296616GO:0015291
GeneOntologyMolecularFunctionprotein tyrosine/serine/threonine phosphatase activity

CDC14C MTMR2 CDC14B

3.07e-0443613GO:0008138
GeneOntologyMolecularFunctiondemethylase activity

KDM5B KDM5C KDM5D

3.29e-0444613GO:0032451
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate 3-phosphatase activity

MTMR2 MTMR1

4.96e-0411612GO:0052629
GeneOntologyMolecularFunctionvoltage-gated chloride channel activity

CLCN3 CLCN4

4.96e-0411612GO:0005247
GeneOntologyMolecularFunctionodorant binding

OR5M10 OR2A7 OR5M1 OR5AR1

6.15e-04127614GO:0005549
GeneOntologyMolecularFunctionphosphatidylinositol-3-phosphate phosphatase activity

MTMR2 MTMR1

8.16e-0414612GO:0004438
GeneOntologyMolecularFunctionphosphatidylinositol monophosphate phosphatase activity

MTMR2 MTMR1

9.40e-0415612GO:0052744
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

KDM5B KDM5C KDM5D

1.04e-0365613GO:0016706
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate phosphatase activity

MTMR2 MTMR1

1.07e-0316612GO:0106018
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC6A13 CLCN3 CLCN4 SLC39A14

1.17e-03151614GO:0008509
GeneOntologyMolecularFunctionvoltage-gated monoatomic anion channel activity

CLCN3 CLCN4

1.21e-0317612GO:0008308
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR5M10 OR2A7 OR2M7 OR5M1 ADGRF4 ADGRF3 OR5AR1 TAAR6 OR10D4P

1.37e-03884619GO:0004930
GeneOntologyMolecularFunctionolfactory receptor activity

OR5M10 OR2A7 OR2M7 OR5M1 OR5AR1 OR10D4P

1.99e-03431616GO:0004984
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC6A13 SLC39A14

2.85e-0326612GO:0015296
GeneOntologyMolecularFunctionphosphatidylinositol bisphosphate phosphatase activity

MTMR2 MTMR1

3.07e-0327612GO:0034593
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A13 CLCN3 CLCN4 SLC17A1 SLC25A11 SLC39A14

3.29e-03477616GO:0022804
GeneOntologyMolecularFunctiondioxygenase activity

KDM5B KDM5C KDM5D

3.36e-0398613GO:0051213
GeneOntologyMolecularFunctionphosphatidylinositol phosphate phosphatase activity

MTMR2 MTMR1

3.78e-0330612GO:0052866
GeneOntologyMolecularFunctionnuclear androgen receptor binding

RNF14 KDM5D

4.56e-0333612GO:0050681
GeneOntologyMolecularFunctioncysteine-type deubiquitinase activity

CYLD USP22 USP1

5.13e-03114613GO:0004843
GeneOntologyMolecularFunctionhistone modifying activity

KDM5B USP22 KDM5C KDM5D

5.28e-03229614GO:0140993
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC6A13 SLC17A1 SLC39A14

5.78e-03119613GO:0015294
GeneOntologyMolecularFunctiondeubiquitinase activity

CYLD USP22 USP1

6.47e-03124613GO:0101005
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC6A13 CLCN3 CLCN4

6.62e-03125613GO:0015108
GeneOntologyMolecularFunctionubiquitin-like protein peptidase activity

CYLD USP22 USP1

8.51e-03137613GO:0019783
GeneOntologyMolecularFunctionantiporter activity

CLCN3 CLCN4 SLC25A11

8.68e-03138613GO:0015297
GeneOntologyCellularComponentsemaphorin receptor complex

PLXNA4 PLXNA1 PLXNA2

6.62e-0613613GO:0002116
DomainLys_sp_deMease-like_dom

KDM5B KDM5C KDM5D

1.13e-074583IPR013637
DomainPLU-1

KDM5B KDM5C KDM5D

1.13e-074583PF08429
Domainzf-C5HC2

KDM5B KDM5C KDM5D

2.83e-075583PF02928
DomainZnf_C5HC2

KDM5B KDM5C KDM5D

2.83e-075583IPR004198
DomainPlexin_cytopl

PLXNA4 PLXNA1 PLXNA2

2.36e-069583PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA4 PLXNA1 PLXNA2

2.36e-069583IPR013548
DomainPlexin

PLXNA4 PLXNA1 PLXNA2

2.36e-069583IPR031148
DomainJmjN

KDM5B KDM5C KDM5D

3.36e-0610583SM00545
DomainJMJN

KDM5B KDM5C KDM5D

3.36e-0610583PS51183
DomainJmjN

KDM5B KDM5C KDM5D

3.36e-0610583PF02375
DomainJmjN

KDM5B KDM5C KDM5D

3.36e-0610583IPR003349
Domain-

KDM5B KDM5C KDM5D

1.26e-05155831.10.150.60
DomainBRIGHT

KDM5B KDM5C KDM5D

1.26e-0515583SM00501
DomainARID_dom

KDM5B KDM5C KDM5D

1.26e-0515583IPR001606
DomainARID

KDM5B KDM5C KDM5D

1.26e-0515583PS51011
DomainARID

KDM5B KDM5C KDM5D

1.26e-0515583PF01388
DomainJmjC

KDM5B KDM5C KDM5D

5.49e-0524583PF02373
DomainLIM

LIMK1 LIMD1 LIMCH1 LHX6

6.23e-0569584PF00412
Domain-

LIMK1 LIMD1 LIMCH1 LHX6

6.59e-05705842.10.110.10
DomainZnf_LIM

LIMK1 LIMD1 LIMCH1 LHX6

6.97e-0571584IPR001781
DomainLIM_DOMAIN_1

LIMK1 LIMD1 LIMCH1 LHX6

6.97e-0571584PS00478
DomainLIM_DOMAIN_2

LIMK1 LIMD1 LIMCH1 LHX6

6.97e-0571584PS50023
DomainLIM

LIMK1 LIMD1 LIMCH1 LHX6

6.97e-0571584SM00132
Domain-

RNF14 KDM5B TRAF2 USP22 MYCBP2 KDM5C MKRN2 KDM5D

7.00e-054495883.30.40.10
DomainIPT

PLXNA4 PLXNA1 PLXNA2

7.88e-0527583SM00429
DomainZnf_RING/FYVE/PHD

RNF14 KDM5B TRAF2 USP22 MYCBP2 KDM5C MKRN2 KDM5D

8.17e-05459588IPR013083
DomainTIG

PLXNA4 PLXNA1 PLXNA2

1.20e-0431583PF01833
DomainSema

PLXNA4 PLXNA1 PLXNA2

1.20e-0431583SM00630
DomainSemap_dom

PLXNA4 PLXNA1 PLXNA2

1.20e-0431583IPR001627
DomainSema

PLXNA4 PLXNA1 PLXNA2

1.20e-0431583PF01403
DomainSEMA

PLXNA4 PLXNA1 PLXNA2

1.20e-0431583PS51004
DomainPSI

PLXNA4 PLXNA1 PLXNA2

1.32e-0432583PF01437
DomainJMJC

KDM5B KDM5C KDM5D

1.32e-0432583PS51184
DomainIPT

PLXNA4 PLXNA1 PLXNA2

1.32e-0432583IPR002909
DomainPlexin_repeat

PLXNA4 PLXNA1 PLXNA2

1.32e-0432583IPR002165
DomainJmjC_dom

KDM5B KDM5C KDM5D

1.32e-0432583IPR003347
DomainJmjC

KDM5B KDM5C KDM5D

1.45e-0433583SM00558
DomainSWIM

ZSWIM1 ZSWIM7

1.97e-047582PF04434
DomainIg_E-set

MYCBP2 PLXNA4 PLXNA1 PLXNA2

3.06e-04104584IPR014756
DomainCl-channel_core

CLCN3 CLCN4

3.36e-049582IPR014743
Domain-

CLCN3 CLCN4

3.36e-0495821.10.3080.10
DomainVoltage_CLC

CLCN3 CLCN4

3.36e-049582PF00654
DomainCl-channel_volt-gated

CLCN3 CLCN4

3.36e-049582IPR001807
DomainZnf_SWIM

ZSWIM1 ZSWIM7

3.36e-049582IPR007527
DomainZF_SWIM

ZSWIM1 ZSWIM7

3.36e-049582PS50966
DomainPSI

PLXNA4 PLXNA1 PLXNA2

3.44e-0444583IPR016201
DomainPSI

PLXNA4 PLXNA1 PLXNA2

3.92e-0446583SM00423
DomainEGF_CA

NID2 HSPG2 EFEMP2 NOTCH4

5.60e-04122584SM00179
DomainEGF-like_Ca-bd_dom

NID2 HSPG2 EFEMP2 NOTCH4

5.95e-04124584IPR001881
DomainPTPc_motif

MTMR2 MTMR1 CDC14B

8.17e-0459583SM00404
DomainTyr_Pase_cat

MTMR2 MTMR1 CDC14B

8.17e-0459583IPR003595
DomainIBR

RNF14 FBXO43

8.42e-0414582SM00647
DomainMyotubularin-like_Pase_dom

MTMR2 MTMR1

8.42e-0414582IPR010569
DomainPPASE_MYOTUBULARIN

MTMR2 MTMR1

8.42e-0414582PS51339
DomainMyotubularin_fam

MTMR2 MTMR1

8.42e-0414582IPR030564
DomainMyotub-related

MTMR2 MTMR1

8.42e-0414582PF06602
DomainIBR

RNF14 FBXO43

8.42e-0414582PF01485
DomainIBR_dom

RNF14 FBXO43

9.70e-0415582IPR002867
DomainZinc_finger_PHD-type_CS

KDM5B KDM5C KDM5D

1.08e-0365583IPR019786
DomainCBS

CLCN3 CLCN4

1.11e-0316582SM00116
DomainGRAM

MTMR2 MTMR1

1.11e-0316582SM00568
DomainUSP_CS

CYLD USP22 USP1

1.13e-0366583IPR018200
DomainUSP_1

CYLD USP22 USP1

1.34e-0370583PS00972
DomainUCH

CYLD USP22 USP1

1.40e-0371583PF00443
DomainUSP_2

CYLD USP22 USP1

1.40e-0371583PS00973
DomainGrowth_fac_rcpt_

NID2 HSPG2 EFEMP2 NOTCH4

1.40e-03156584IPR009030
DomainUSP_3

CYLD USP22 USP1

1.46e-0372583PS50235
DomainUSP_dom

CYLD USP22 USP1

1.46e-0372583IPR028889
DomainPeptidase_C19_UCH

CYLD USP22 USP1

1.46e-0372583IPR001394
DomainTyr_Pase_AS

MTMR2 MTMR1 CDC14B

1.52e-0373583IPR016130
DomainPHD

KDM5B KDM5C KDM5D

1.64e-0375583PF00628
DomainCBS_dom

CLCN3 CLCN4

1.74e-0320582IPR000644
DomainCBS

CLCN3 CLCN4

1.74e-0320582PF00571
DomainCBS

CLCN3 CLCN4

1.74e-0320582PS51371
DomainZnf_PHD-finger

KDM5B KDM5C KDM5D

1.90e-0379583IPR019787
DomainGRAM

MTMR2 MTMR1

2.10e-0322582PF02893
DomainGRAM

MTMR2 MTMR1

2.10e-0322582IPR004182
DomainTYR_PHOSPHATASE_1

MTMR2 MTMR1 CDC14B

2.42e-0386583PS00383
DomainEGF_CA

NID2 EFEMP2 NOTCH4

2.42e-0386583PF07645
DomainTYR_PHOSPHATASE_2

MTMR2 MTMR1 CDC14B

2.50e-0387583PS50056
DomainTYR_PHOSPHATASE_dom

MTMR2 MTMR1 CDC14B

2.50e-0387583IPR000387
DomainRho_GTPase_activation_prot

PLXNA4 PLXNA1 PLXNA2

2.59e-0388583IPR008936
DomainPHD

KDM5B KDM5C KDM5D

2.67e-0389583SM00249
DomainZnf_PHD

KDM5B KDM5C KDM5D

2.84e-0391583IPR001965
Domain-

MTMR2 MTMR1 CDC14B

2.93e-03925833.90.190.10
DomaincEGF

NID2 EFEMP2

2.94e-0326582IPR026823
DomaincEGF

NID2 EFEMP2

2.94e-0326582PF12662
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

LIMK1 PLXNA4 PLXNA1 PLXNA2

9.70e-0814464MM15029
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

LIMK1 PLXNA4 PLXNA1 PLXNA2

1.75e-0716464M16498
PathwayREACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION

PLXNA4 PLXNA1 PLXNA2

2.69e-069463MM15030
PathwayREACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION

PLXNA4 PLXNA1 PLXNA2

1.15e-0514463M7578
PathwayREACTOME_CRMPS_IN_SEMA3A_SIGNALING

PLXNA4 PLXNA1 PLXNA2

1.44e-0515463MM15031
PathwayREACTOME_CRMPS_IN_SEMA3A_SIGNALING

PLXNA4 PLXNA1 PLXNA2

1.77e-0516463M8245
PathwayREACTOME_SEMAPHORIN_INTERACTIONS

LIMK1 PLXNA4 PLXNA1 PLXNA2

2.22e-0551464MM14967
PathwayREACTOME_OTHER_SEMAPHORIN_INTERACTIONS

PLXNA4 PLXNA1 PLXNA2

3.04e-0519463M10959
PathwayREACTOME_SEMAPHORIN_INTERACTIONS

LIMK1 PLXNA4 PLXNA1 PLXNA2

5.46e-0564464M7923
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM5B KDM5C KDM5D

1.12e-0429463MM14934
PathwayWP_GPCRS_ODORANT

OR2A7 ADGRF4 ADGRF3 OR5AR1 TAAR6

1.52e-04157465MM15872
PathwayWP_PHOSPHATIDYL_INOSITOL_PHOSPHATE_PATHWAY

PIK3CD MTMR2 MTMR1

4.47e-0446463M48317
PathwayWP_PHOSPHOINOSITIDES_METABOLISM

PIK3CD MTMR2 MTMR1

5.39e-0449463M40046
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM5B KDM5C KDM5D

5.72e-0450463M27232
PathwayREACTOME_ORGANIC_ANION_TRANSPORTERS

SLC17A1 SLC25A11

6.73e-0412462M27350
PathwayREACTOME_ORGANIC_ANION_TRANSPORTERS

SLC17A1 SLC25A11

6.73e-0412462MM15087
PathwayREACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE

PIK3CD MTMR2 MTMR1

6.80e-0453463M662
PathwayWP_NRP1TRIGGERED_SIGNALING_IN_PANCREATIC_CANCER

PLXNA4 PLXNA1 PLXNA2

7.18e-0454463M42568
PathwayKEGG_RIBOFLAVIN_METABOLISM

MTMR2 MTMR1

1.21e-0316462M6889
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

LIMK1 PIK3CD PLXNA4 PLXNA1 PLXNA2

1.54e-03261465MM15676
Pubmed

Structural Basis for Plexin Activation and Regulation.

PLXNA4 PLXNA1 PLXNA2

5.13e-09361327397516
Pubmed

Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.

PLXNA4 PLXNA1 PLXNA2

5.13e-09361318625214
Pubmed

Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.

KDM5B KDM5C KDM5D

2.05e-08461316541399
Pubmed

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

KDM5B KDM5C KDM5D

2.05e-08461317320160
Pubmed

Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.

PLXNA4 PLXNA1 PLXNA2

2.05e-08461311306810
Pubmed

PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.

PLXNA4 PLXNA1 PLXNA2

2.05e-08461325518740
Pubmed

Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.

PLXNA4 PLXNA1 PLXNA2

1.79e-07761319063725
Pubmed

Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.

PLXNA4 PLXNA1 PLXNA2

1.79e-07761319655386
Pubmed

The expression of plexins during mouse embryogenesis.

PLXNA4 PLXNA1 PLXNA2

2.86e-07861315661641
Pubmed

Integration of opposing semaphorin guidance cues in cortical axons.

PLXNA4 PLXNA1 PLXNA2

2.86e-07861322368082
Pubmed

The role of neuropilins in cell signalling.

PLXNA4 PLXNA1 PLXNA2

4.28e-07961319909241
Pubmed

Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.

PLXNA4 PLXNA1 PLXNA2

6.11e-071061318804103
Pubmed

Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.

PLXNA4 PLXNA1 PLXNA2

1.12e-061261325839327
Pubmed

PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons.

PLXNA4 PLXNA1 PLXNA2

1.12e-061261331690636
Pubmed

On and off retinal circuit assembly by divergent molecular mechanisms.

PLXNA4 PLXNA1 PLXNA2

1.12e-061261324179230
Pubmed

Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.

PLXNA4 PLXNA1 PLXNA2

1.12e-061261328407732
Pubmed

Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.

PLXNA4 PLXNA1 PLXNA2

1.12e-061261321270798
Pubmed

Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.

PLXNA4 PLXNA1 PLXNA2

1.12e-061261323991118
Pubmed

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.

KDM5B KDM5C KDM5D

1.45e-061361324619213
Pubmed

Plexin signaling via off-track and rho family GTPases.

PLXNA4 PLXNA1 PLXNA2

1.45e-061361311604131
Pubmed

Functional assembly of accessory optic system circuitry critical for compensatory eye movements.

PLXNA4 PLXNA1 PLXNA2

1.45e-061361325959730
Pubmed

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.

PLXNA4 PLXNA1 PLXNA2

1.45e-061361310520995
Pubmed

Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.

PLXNA4 PLXNA1 PLXNA2

1.45e-061361322723296
Pubmed

A midline switch of receptor processing regulates commissural axon guidance in vertebrates.

PLXNA4 PLXNA1 PLXNA2

1.84e-061461320159958
Pubmed

Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus.

PLXNA4 PLXNA1 PLXNA2

2.83e-061661318489001
Pubmed

Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.

PLXNA4 PLXNA1 PLXNA2

2.83e-061661317356169
Pubmed

Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.

PLXNA4 PLXNA1 PLXNA2

2.83e-061661322632726
Pubmed

Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration.

CLCN3 CLCN4

3.03e-06261232118314
Pubmed

Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.

KDM5C KDM5D

3.03e-06261232081420
Pubmed

Plexin/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A.

PLXNA1 PLXNA2

3.03e-06261210781943
Pubmed

Overexpression of CDC14B causes mitotic arrest and inhibits zygotic genome activation in mouse preimplantation embryos.

CDC14C CDC14B

3.03e-06261219923902
Pubmed

The Cdc14B phosphatase displays oncogenic activity mediated by the Ras-Mek signaling pathway.

CDC14C CDC14B

3.03e-06261221502810
Pubmed

Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.

KDM5C KDM5D

3.03e-0626129060413
Pubmed

Alcohol-associated fibrosis in females is mediated by female-specific activation of lysine demethylases KDM5B and KDM5C.

KDM5B KDM5C

3.03e-06261235468265
Pubmed

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.

KDM5C KDM5D

3.03e-06261210441747
Pubmed

Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

KDM5C KDM5D

3.03e-06261216416087
Pubmed

Preferential association with ClC-3 permits sorting of ClC-4 into endosomal compartments.

CLCN3 CLCN4

3.03e-06261228972156
Pubmed

Birth and rapid subcellular adaptation of a hominoid-specific CDC14 protein.

CDC14C CDC14B

3.03e-06261218547142
Pubmed

A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.

KDM5C KDM5D

3.03e-0626127524912
Pubmed

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.

PLXNA4 PLXNA1 PLXNA2

3.43e-061761311683995
Pubmed

Semaphorin signaling facilitates cleft formation in the developing salivary gland.

PLXNA4 PLXNA1 PLXNA2

3.43e-061761317626059
Pubmed

Interactions between plexin-A2, plexin-A4, and semaphorin 6A control lamina-restricted projection of hippocampal mossy fibers.

PLXNA4 PLXNA2

9.07e-06361217296555
Pubmed

Early-onset aging and defective DNA damage response in Cdc14b-deficient mice.

CDC14C CDC14B

9.07e-06361221262768
Pubmed

Identification of plexin family molecules in mice.

PLXNA1 PLXNA2

9.07e-0636128806646
Pubmed

Structural analysis of human KDM5B guides histone demethylase inhibitor development.

KDM5B KDM5C

9.07e-06361227214403
Pubmed

Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription.

CDC14C CDC14B

9.07e-06361222355704
Pubmed

Fyn-dependent phosphorylation of PlexinA1 and PlexinA2 at conserved tyrosines is essential for zebrafish eye development.

PLXNA1 PLXNA2

9.07e-06361229091353
Pubmed

Identification of a mouse male-specific transplantation antigen, H-Y.

KDM5C KDM5D

9.07e-0636127544442
Pubmed

Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization.

KDM5B KDM5C

9.07e-06361238230606
Pubmed

Plexins promote Hedgehog signaling through their cytoplasmic GAP activity.

PLXNA1 PLXNA2

9.07e-06361236169302
Pubmed

Differential expression of plexin-A subfamily members in the mouse nervous system.

PLXNA1 PLXNA2

9.07e-06361211241833
Pubmed

CDC14B acts through FZR1 (CDH1) to prevent meiotic maturation of mouse oocytes.

CDC14C CDC14B

9.07e-06361219129509
Pubmed

Role of transmembrane semaphorin Sema6A in oligodendrocyte differentiation and myelination.

PLXNA4 PLXNA2

9.07e-06361222777942
Pubmed

Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.

KDM5B KDM5C

9.07e-06361226645689
Pubmed

Deubiquitinases A20 and CYLD modulate costimulatory signaling via CD137 (4-1BB).

CYLD TRAF2

9.07e-06361229296520
Pubmed

Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair.

CDC14C CDC14B

9.07e-06361226283732
Pubmed

A semaphorin code defines subpopulations of spinal motor neurons during mouse development.

PLXNA4 PLXNA1 PLXNA2

1.01e-052461315869472
Pubmed

A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.

PLXNA4 PLXNA1 PLXNA2

1.01e-052461328893946
Pubmed

Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.

PLXNA4 PLXNA1 PLXNA2

1.63e-052861318617019
Pubmed

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination.

CYLD TRAF2

1.81e-05461212917691
Pubmed

Functional redundancy in the myotubularin family.

MTMR2 MTMR1

1.81e-05461211846405
Pubmed

Role of ClC-5 in renal endocytosis is unique among ClC exchangers and does not require PY-motif-dependent ubiquitylation.

CLCN3 CLCN4

1.81e-05461220351103
Pubmed

CDC14A phosphatase is essential for hearing and male fertility in mouse and human.

CDC14C CDC14B

1.81e-05461229293958
Pubmed

Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice.

CYLD TRAF2

1.81e-05461217053834
Pubmed

X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.

KDM5C KDM5D

1.81e-05461232732223
Pubmed

CYLD regulates RhoA activity by modulating LARG ubiquitination.

CYLD TRAF2

1.81e-05461223405219
Pubmed

Determination of cell adhesion sites of neuropilin-1.

PLXNA1 PLXNA2

1.81e-05461210725340
Pubmed

A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human.

KDM5C KDM5D

1.81e-0546127951230
Pubmed

Hematopoietic stem cell quiescence and function are controlled by the CYLD-TRAF2-p38MAPK pathway.

CYLD TRAF2

1.81e-05461225824820
Pubmed

Myotubularins, a large disease-associated family of cooperating catalytically active and inactive phosphoinositides phosphatases.

MTMR2 MTMR1

1.81e-05461212925573
Pubmed

Mis12 controls cyclin B1 stabilization via Cdc14B-mediated APC/CCdh1 regulation during meiotic G2/M transition in mouse oocytes.

CDC14C CDC14B

1.81e-05461232341029
Pubmed

A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.

PLXNA1 PLXNA2

1.81e-0546128570614
Pubmed

Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.

KDM5B KDM5C KDM5D

2.70e-053361326864203
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR5M10 OR2A7 OR2M7 OR5M1 OR5AR1 OR10D4P

2.95e-0534061611875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR5M10 OR2A7 OR2M7 OR5M1 OR5AR1 OR10D4P

2.95e-0534061611802173
Pubmed

Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens.

NID2 HSPG2

3.02e-05561212243745
Pubmed

MicroRNAs regulate KDM5 histone demethylases in breast cancer cells.

KDM5B KDM5C

3.02e-05561226621457
Pubmed

Mapping of binding sites for nidogens, fibulin-2, fibronectin and heparin to different IG modules of perlecan.

NID2 HSPG2

3.02e-05561211493006
Pubmed

Guidance-cue control of horizontal cell morphology, lamination, and synapse formation in the mammalian outer retina.

PLXNA4 PLXNA2

3.02e-05561222593055
Pubmed

The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation.

CYLD TRAF2

3.02e-05561222057290
Pubmed

Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.

PLXNA1 PLXNA2

3.02e-05561225313870
Pubmed

An essential role for ClC-4 in transferrin receptor function revealed in studies of fibroblasts derived from Clcn4-null mice.

CLCN3 CLCN4

3.02e-05561219339555
Pubmed

A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast.

MTMR2 MTMR1

3.02e-0556128640223
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR5M10 OR2A7 OR2M7 OR5M1 OR5AR1 OR10D4P

3.10e-0534361632295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR5M10 OR2A7 OR2M7 OR5M1 OR5AR1 OR10D4P

3.25e-0534661614611657
Pubmed

Semaphorin-Plexin signaling influences early ventral telencephalic development and thalamocortical axon guidance.

PLXNA4 PLXNA2

4.52e-05661228438183
Pubmed

Roles of semaphorin-6B and plexin-A2 in lamina-restricted projection of hippocampal mossy fibers.

PLXNA4 PLXNA2

4.52e-05661220484647
Pubmed

Nidogen-2: a new basement membrane protein with diverse binding properties.

NID2 HSPG2

4.52e-0566129733643
Pubmed

Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock.

KDM5B KDM5C

4.52e-05661221960634
Pubmed

Expression of CLCN voltage-gated chloride channel genes in human blood vessels.

CLCN3 CLCN4

4.52e-05661210198195
Pubmed

Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteins.

NID2 HSPG2

4.52e-05661210544250
Pubmed

The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin.

NID2 HSPG2

4.52e-05661211956183
Pubmed

Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages.

PLXNA1 PLXNA2

4.52e-05661219480842
Pubmed

A comparative analysis of the fibulin protein family. Biochemical characterization, binding interactions, and tissue localization.

NID2 EFEMP2

6.32e-05761217324935
Pubmed

Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors.

PLXNA1 PLXNA2

6.32e-05761210520994
Pubmed

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.

KDM5B KDM5C

6.32e-05761228262558
Pubmed

TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.

PLXNA4 PLXNA1 PLXNA2

7.88e-054761335462405
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

KDM5B LIMK1 LIMD1 KDM5C MKRN2 KDM5D PLXNA1 PLXNA2

8.14e-0580861820412781
Pubmed

Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions.

ADGRF4 ADGRF3

8.42e-05861212435584
Pubmed

Specific ablation of the nidogen-binding site in the laminin gamma1 chain interferes with kidney and lung development.

NID2 HSPG2

8.42e-05861212015298
InteractionSEMA6D interactions

MKRN2 PLXNA4 PLXNA1 PLXNA2

4.55e-0723564int:SEMA6D
InteractionSEMA5A interactions

PLXNA4 PLXNA1 PLXNA2

7.06e-077563int:SEMA5A
InteractionSEMA5B interactions

PLXNA4 PLXNA1 PLXNA2

9.03e-0615563int:SEMA5B
InteractionSEMA6A interactions

MKRN2 PLXNA4 PLXNA1 PLXNA2

2.82e-0563564int:SEMA6A
InteractionIGFL3 interactions

MYCBP2 LRP11 MTMR1 PLXNA2

5.61e-0575564int:IGFL3
GeneFamilyPlexins

PLXNA4 PLXNA1 PLXNA2

1.97e-069533683
GeneFamilyAT-rich interaction domain containing

KDM5B KDM5C KDM5D

1.06e-0515533418
GeneFamilyPHD finger proteins|Lysine demethylases

KDM5B KDM5C KDM5D

4.61e-0524533485
GeneFamilyAdhesion G protein-coupled receptors, subfamily F

ADGRF4 ADGRF3

8.38e-055532916
GeneFamilyZinc fingers SWIM-type|Mitogen-activated protein kinase kinase kinases

ZSWIM1 ZSWIM7

3.00e-04953290
GeneFamilyChloride voltage-gated channels

CLCN3 CLCN4

3.74e-0410532302
GeneFamilyUbiquitin specific peptidases

CYLD USP22 USP1

5.91e-0456533366
GeneFamilyLIM domain containing

LIMK1 LIMD1 LIMCH1

6.89e-04595331218
GeneFamilyMyotubularins|Phosphoinositide phosphatases

MTMR2 MTMR1

8.64e-0415532903
GeneFamilyPHD finger proteins

KDM5B KDM5C KDM5D

2.33e-039053388
GeneFamilyPhosphoinositide phosphatases

MTMR2 MTMR1

3.95e-03325321079
GeneFamilyOlfactory receptors, family 5

OR5M10 OR5M1 OR5AR1

4.33e-03112533152
GeneFamilySolute carriers

SLC6A13 SLC17A1 SLC25A11 SLC39A14 SLC38A8

5.89e-03395535752
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 HSPG2 LHX6 PLXNA2 NOTCH4

6.87e-0619760562c0a90869431e582bb7bb329e0b0cc59123d3d1
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 HSPG2 LHX6 PLXNA2 NOTCH4

6.87e-0619760516f0eb047df9d702518f82ee99c6e7dc1350b2fb
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 HSPG2 LHX6 PLXNA2 NOTCH4

6.87e-061976059e948b2e0f7e426f1e6f95bbbf4282fbddc2b99d
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

NID2 MYCBP2 EFEMP2 LIMCH1 SLC39A14

7.22e-06199605fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NID2 MYCBP2 EFEMP2 PLXNA4 LIMCH1

7.22e-06199605a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

NID2 MYCBP2 EFEMP2 PLXNA4 LIMCH1

7.39e-06200605a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 HHIPL2 LHX6 NOTCH4

6.75e-051626045428c9fdb816f564395ebb4520448e5f3a42b025
ToppCellInfluenza_Severe-pDC|World / Disease group and Cell class

ZFAT PLXNA4 NOTCH4 TLCD5

7.42e-05166604bd25ce4c03c3d6cd9d986b9be1d355da52f0f2d7
ToppCellInfluenza_Severe-pDC|Influenza_Severe / Disease group and Cell class

ZFAT PLXNA4 NOTCH4 TLCD5

7.42e-05166604b43a5cd4d28118cf6e56a435deb8ea9435608a90
ToppCell10x5'-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue

OR2A7 ZFAT PLXNA4 TLCD5

7.77e-0516860490f713dae3fcbd6ca801a019e3861c263ff3366b
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

HSPG2 ZFAT PLXNA4 NOTCH4

7.77e-05168604dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCellsevere_influenza-pDC|World / disease group, cell group and cell class (v2)

ZFAT PLXNA4 NOTCH4 TLCD5

8.13e-05170604b9c08af83241666bbdbed9109cadcd088c0f647d
ToppCellnormal-na-Lymphocytic_B-B_plasma-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

HSPG2 CLCN3 PAQR6 KDM5D

8.13e-05170604c5b87974dfddf9780051f7f5693eeeb0c606a3fe
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A13 ZFAT SLC17A1 OTOGL

8.70e-051736048888434641ea554a9b62c436e87920378eef29cd
ToppCellsevere_influenza-pDC|severe_influenza / disease group, cell group and cell class (v2)

ZFAT PLXNA4 NOTCH4 TLCD5

8.90e-05174604d8d2ded5812ed3b3db4109585714a6513c13326a
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP11 GOLGA7B CDC14B PLXNA1

9.10e-0517560438dec78efc99fe23479cba68cfa441e62bd6a08b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 EFEMP2 USP1 NOTCH4

9.30e-051766041df7b6ce2519ad99bacbbaf1a8d5929e11513faa
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP11 GOLGA7B CDC14B PLXNA1

9.72e-05178604d3a75a8082e70543b84c35d53fe77625300d19fa
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP11 GOLGA7B CDC14B PLXNA1

9.72e-05178604b2cda1df801b1a1a41e3dd2808baef37765cd804
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 SLC6A13 LIMD1 PLXNA1

9.93e-051796041603117b52623663458a977c94bf7f9f6c1114b8
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b-Inhibitory_Gad1Gad2_Id2.Bcl11b_(Interneuron,_Neurogliaform2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC17A1 OTOGL LHX6

1.06e-0468603cfd75c373e10b3761666ccd445ba74755efeb95f
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC17A1 OTOGL LHX6

1.06e-0468603c25fb921dc83eecdc337353894829ae6b5192353
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b-Inhibitory_Gad1Gad2_Id2.Bcl11b_(Interneuron,_Neurogliaform2)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC17A1 OTOGL LHX6

1.06e-0468603712f5f4d3a1e0c0db1a340332876206b93bdac31
ToppCell(7)_DC_plasmacytoid|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ZFAT PLXNA4 NOTCH4 TLCD5

1.08e-041836042c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 AMHR2 PLXNA2 NOTCH4

1.08e-04183604dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 AMHR2 PLXNA2 NOTCH4

1.08e-041836044759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCellsystemic_lupus_erythematosus-managed-Myeloid-plasmacytoid_dendritic_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ZFAT PLXNA4 NOTCH4 TLCD5

1.13e-04185604cc5152d3055375172bdf84f442b233c8fbd422b3
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 HSPG2 LHX6 NOTCH4

1.15e-04186604a906020a8df6fcca474b278f746c553b177a56b4
ToppCelldroplet-Heart-HEART-1m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A13 PAQR6 GOLGA7B DNAH11

1.15e-04186604fddc6b93f98b10aaf8d4ebc142b46d8213f3129d
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|368C / Donor, Lineage, Cell class and subclass (all cells)

LIMD1 MTMR1 CPLANE1 DNAH11

1.17e-04187604b827d9da7032bf051756ddf88352af922eb0f87b
ToppCellHealthy-HSPC|World / disease group, cell group and cell class

HSPG2 AMHR2 KDM5B TLCD5

1.17e-041876048cd9e5499e5c2b2321ecbcf780df37fe0f165ac9
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|368C / Donor, Lineage, Cell class and subclass (all cells)

LIMD1 MTMR1 CPLANE1 DNAH11

1.17e-0418760461c00604dda8b36a5c3eea6554e5601aa1b884f7
ToppCellCOVID-19_Severe-pDC|World / disease group, cell group and cell class

ZFAT PLXNA4 NOTCH4 TLCD5

1.20e-041886044c8e328b8206120708b05ea3c5865a0200dc5c4e
ToppCellSevere-Lymphoid-NK-Treg|Severe / Condition, Lineage, Cell class and cell subclass

ZFAT USP22 AASDH GOLGA7B

1.25e-04190604e67803bf55a3f8e47a69ff1829c9100f870d7527
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 HSPG2 PLXNA2 NOTCH4

1.25e-0419060406bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RNF14 LIMK1 MYCBP2 GOLGA7B

1.27e-041916045d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RNF14 LIMK1 MYCBP2 GOLGA7B

1.27e-0419160473dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 SLC39A14 LHX6 NOTCH4

1.33e-04193604c0f0052c24b7fe9e21d2bc6c38047a8e755f87b6
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 SLC39A14 LHX6 NOTCH4

1.33e-04193604682ce63b73a7d02eef240673db67058d7507f744
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 SLC39A14 LHX6 NOTCH4

1.38e-0419560453b83e16b350100b1d5791a9c42bd98e37cbc0af
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 LIMCH1 PLXNA2 NOTCH4

1.38e-04195604d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 LIMCH1 LHX6 NOTCH4

1.41e-04196604a0ba408b802fa6d6e42e6d234b6879fdb1583f81
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 HSPG2 LHX6 NOTCH4

1.41e-04196604ed818de15f84f7f28bd06fd69d7876710da232a0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 LIMCH1 LHX6 NOTCH4

1.41e-04196604ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellmild-pDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZFAT PLXNA4 NOTCH4 TLCD5

1.44e-041976040cb00daa6943f7a7fb34a8fdf51188646af65686
ToppCellInfluenza-Influenza_Severe-Myeloid-pDC|Influenza_Severe / Disease, condition lineage and cell class

ZFAT PLXNA4 NOTCH4 TLCD5

1.44e-04197604e8e6f71e6dc8a695e4321a18543c1df63dd62f3e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 HSPG2 PLXNA2 NOTCH4

1.44e-041976049244f087ba4b60fdc81d54ce91860de715b3e12c
ToppCellmild-pDC|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZFAT PLXNA4 NOTCH4 TLCD5

1.44e-0419760415230a54fa5903dd728de1a0ad633bd2d2c7a04d
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NID2 HSPG2 LIMCH1 PLXNA1

1.46e-04198604b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCellsevere-pDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZFAT PLXNA4 NOTCH4 TLCD5

1.46e-041986043c4820a8391088682fb3e47b914f872533bae227
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 HSPG2 PLXNA2 NOTCH4

1.46e-04198604218f33e068eb126458ec33176de3cfa6fc06ddf0
ToppCellCOVID-19-COVID-19_Severe-Myeloid-pDC|COVID-19_Severe / Disease, condition lineage and cell class

ZFAT PLXNA4 NOTCH4 TLCD5

1.46e-04198604033ed362333e1d33f2aeea8da5865d2228d154dc
ToppCell3'-Child04-06-SmallIntestine-Endothelial-blood_vessel_EC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 LIMCH1 LHX6 NOTCH4

1.46e-0419860499be7a7a84199dac598e993a5a0144d9030f13ce
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 LIMCH1 PLXNA2 NOTCH4

1.46e-0419860458508a8df2714d769f137794c29441a7bd38b350
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 LIMCH1 LHX6 NOTCH4

1.46e-041986045b86dc00acf8ac2ede008f5d79c09996485bf250
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 HSPG2 PLXNA2 NOTCH4

1.46e-041986047cddd474416651088a4e08edfc0ac420ff10a5fe
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 HSPG2 PLXNA2 NOTCH4

1.46e-04198604e1fa02184ce93c4f8aa5cf04b70949cd4c425ff0
ToppCellILEUM-inflamed-(7)_CD36+_endothelial_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

HSPG2 LIMCH1 PLXNA2 NOTCH4

1.46e-0419860405d6558c7990ad2277db999025a073d29b273dfc
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 LIMCH1 LHX6 NOTCH4

1.46e-04198604f7a957e8f09d54a55a5dbecfaa9cdf01e6fd543d
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HSPG2 PLXNA4 LHX6 NOTCH4

1.49e-041996043a4deea6e11a0555d27497b7c9983350797aac69
ToppCellMS-IIF-Myeloid-pDC|IIF / Disease, condition lineage and cell class

ZFAT PLXNA4 NOTCH4 TLCD5

1.49e-04199604e262ee854e64d87460bee810c14d6cbe744460e8
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NID2 PLXNA4 LIMCH1 SLC39A14

1.49e-041996048b86c69aaf60feff53aa782559cfece7342a23de
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 HSPG2 PLXNA2 NOTCH4

1.49e-041996040602e2b2aa56d106da63bd342a38bef437b4d496
ToppCellCOVID-19-COVID-19_Severe-Others-HSPC|COVID-19_Severe / Disease, condition lineage and cell class

HSPG2 KDM5B LIMCH1 TLCD5

1.49e-0419960425de67b6c9c8d6bb9a538e071a40ef865906c95d
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 HSPG2 PLXNA2 NOTCH4

1.49e-04199604463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts|LPS_only / Treatment groups by lineage, cell group, cell type

NID2 MYCBP2 EFEMP2 LIMCH1

1.49e-041996041a0add79f4e34078b3475eb11c85a4234bda197c
ToppCellLPS_only-Mesenchymal_fibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

NID2 MYCBP2 EFEMP2 LIMCH1

1.49e-04199604211c3a08f2d484ab7a3368006767289088f0d957
ToppCell5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 LIMCH1 LHX6 NOTCH4

1.49e-04199604258d59cf811bf1668ffbb5f18f961021f660de62
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 LIMCH1 LHX6 NOTCH4

1.52e-04200604cd3c638961144a2fc91c437a173cc37c7452fa74
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal|GW16 / Sample Type, Dataset, Time_group, and Cell type.

PLXNA4 LIMCH1 GOLGA7B PLXNA2

1.52e-0420060484e4565d28a02700bf7f6730d1b3a58744ca0aea
ToppCellnormal_Lung-Endothelial_cells-Stalk-like_ECs|Endothelial_cells / Location, Cell class and cell subclass

HSPG2 MYCBP2 LIMCH1 LHX6

1.52e-04200604413ac64bbe95b8c921c5396d8b5f298fec8c4f82
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 LIMCH1 LHX6 NOTCH4

1.52e-04200604ae6cc5462a8a254682793fb8cc348b9721c729bf
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 LIMCH1 LHX6 NOTCH4

1.52e-042006049e44da8aaac239ed69d674dcd53800c5eaf397cb
ToppCell5'-Adult-SmallIntestine-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 LIMCH1 LHX6 NOTCH4

1.52e-042006042554b77edfe3d378296b0b25625caacbfb1c0e76
ToppCellILEUM-non-inflamed-(7)_CD36+_endothelial_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

HSPG2 LIMCH1 PLXNA2 NOTCH4

1.52e-0420060445755a597725015dc3ee36f9166f9e82f6f9c603
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 HSPG2 PLXNA2 NOTCH4

1.52e-04200604061ba851f941c616ddb462512e826c412881c3ce
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

USP22 MKRN2 ZSWIM7

4.28e-04109603cc43c221487a712546917cc3253c158a1fc1fd7a
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_3|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

PAQR6 LIMCH1 ZSWIM1

8.15e-041366035e209185b5f6e9347829fc9066f0b2c3711df057
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NID2 HSPG2 SLC6A13

9.23e-04142603f4e4cde228149d5a536fbf0517ed71d81e296faf
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Cortical_neuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

PLXNA4 LIMCH1 PLXNA2

1.04e-03148603a1269312903fc27830c1835dabf660c659a711be
ToppCell10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-MPP_myeloid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

KDM5B MKRN2 LHX6

1.08e-03150603040468880f69b050c7e992749a165280eb6e61ef
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZFAT CLCN4 PLXNA4

1.08e-0315060357f21ad380fd1350a2c25d75ad8c3b763ded53ec
ToppCellmild_COVID-19_(asymptomatic)-NK_CD56bright|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

HSPG2 MTMR2 PAQR6

1.10e-031516032470162f4b56bc505db166a6eb0fa54847759df8
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A13 ADGRF4 DNAH11

1.14e-03153603d6526d17826470534b766df144c74e73eb83fdad
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LHX6 MUCL3 NOTCH4

1.19e-03155603babcb9e548f04ace8157d506d27c5941c692c491
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 LHX6 NOTCH4

1.21e-03156603f894fac4e44a23718b20ad80c9677bf4f2118002
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 MUCL3 NOTCH4

1.21e-03156603ea9223bb6450b22df11efa1705ab72dab005244a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 MUCL3 NOTCH4

1.21e-03156603586b5509074c4cc359e9e31a968c2ded71c994ca
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

HSPG2 KDM5B DMXL1

1.21e-03156603abea3c183d32062b009a79a2bdf861021989c7ef
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Serous_adenocarcinoma-3|TCGA-Endometrium / Sample_Type by Project: Shred V9

ADGRF4 MUCL3 TAAR6

1.23e-03157603ef70abc999be3a2c1eed7d21aef4b484f69d8567
ToppCellsevere_COVID-19-pDC|World / disease group, cell group and cell class (v2)

HSPG2 PLXNA4 PLXNA1

1.28e-03159603e1c48c4ceda116826819ff9adeed7bad6a58844d
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

NID2 HSPG2 SLC6A13

1.28e-0315960392049a8d8fc9997d8d0d76500c72596a9b2394e0
ToppCellsevere_COVID-19-pDC|severe_COVID-19 / disease group, cell group and cell class (v2)

HSPG2 PLXNA4 PLXNA1

1.28e-03159603ea5088d27e42b8850455764d53b757ea8d8f14bc
ToppCellCOVID_non-vent-Lymphocytic-Dendritic-pDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ZFAT PLXNA4 NOTCH4

1.30e-0316060361f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCellCOVID_non-vent-Lymphocytic-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ZFAT PLXNA4 NOTCH4

1.30e-0316060334b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCell(06)_Krt4/13+-(2)_48hpi|(06)_Krt4/13+ / shred by cell type and Timepoint

CLCN3 CDC14B

1.32e-03406021e42cd186ee06ac9345e16ede649a72c15bdf2f8
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LIMD1 LIMCH1 SLC38A8

1.33e-03161603b19f82dd98a3064581793711bb70373f18abecd9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 MUCL3 NOTCH4

1.35e-03162603c399b9e4854916a59f5cae2d8dbf19660f8759be
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 MUCL3 NOTCH4

1.35e-03162603a291248b693c771845174393934a782f1d8bd7ce
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYLD PIK3CD LRP11

1.37e-031636034af92b211d12c5b88b65bb746242cd702b545bd0
DrugFenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; PC3; HT_HG-U133A

TRAF2 STS CLCN3 ZNF330 MTMR2 MTMR1 CDC14B

7.99e-071956073714_DN
DrugCefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; MCF7; HT_HG-U133A

CYLD HSPG2 LIMK1 TRAF2 MTMR1 LIMCH1 CDC14B

8.85e-071986073581_DN
DrugFlunarizine dihydrochloride [30484-77-6]; Up 200; 8.4uM; PC3; HT_HG-U133A

CYLD NID2 KDM5B STS LIMD1 LIMCH1

1.28e-051966067252_UP
DrugDeoxycorticosterone [64-85-7]; Down 200; 12.2uM; PC3; HT_HG-U133A

LIMK1 CLCN4 LIMD1 MTMR1 LIMCH1 PLXNA2

1.32e-051976066758_DN
DrugAlprostadil [745-65-3]; Down 200; 11.2uM; PC3; HT_HG-U133A

CYLD STS KDM5C EFEMP2 CPLANE1 CDC14B

1.36e-051986064099_DN
DrugMonocrotaline [315-22-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A

STS CLCN3 KDM5C MTMR2 LHX6 PLXNA1

1.36e-051986062749_DN
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5B KDM5C KDM5D

3.03e-084593DOID:0060809 (implicated_via_orthology)
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5B KDM5C KDM5D

4.17e-0616593DOID:0050888 (implicated_via_orthology)
DiseaseDent disease (implicated_via_orthology)

CLCN3 CLCN4

1.18e-053592DOID:0050699 (implicated_via_orthology)
Diseasealcohol use disorder (implicated_via_orthology)

KDM5B PIK3CD KDM5C ADGRF3 KDM5D

4.49e-05195595DOID:1574 (implicated_via_orthology)
Diseaseosteopetrosis (implicated_via_orthology)

CLCN3 CLCN4

8.20e-057592DOID:13533 (implicated_via_orthology)
Diseasecentronuclear myopathy X-linked (implicated_via_orthology)

MTMR2 MTMR1

1.40e-049592DOID:0111225 (implicated_via_orthology)
Diseaseintellectual disability (implicated_via_orthology)

KDM5B KDM5C KDM5D

4.63e-0475593DOID:1059 (implicated_via_orthology)
DiseaseBronchiectasis

PIK3CD DNAH11

8.85e-0422592C0006267
DiseaseCharcot-Marie-Tooth disease (implicated_via_orthology)

MTMR2 MTMR1

1.05e-0324592DOID:10595 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
CLAAAFLCHFLYLAT

ADGRF3

841

Q8IZF5
GSCNFYITLLDCFHA

CDC14B

171

O60729
CCLVFFLSTECSHYR

ADGRF4

11

Q8IZF3
LFSLCYFHACVAGRL

DNAH11

4081

Q96DT5
KIFFGSHDCFIYCCN

AASDH

991

Q4L235
ACCCGNFFSSLFSKY

CLCN4

231

P51793
GSCNFYITLLDCFHA

CDC14C

141

A4D256
CIYQCLCGSHNYSSF

DMXL1

2241

Q9Y485
LFTCSCGTDFCNANY

AMHR2

106

Q16671
FGILSNCNHTYCLSC

MKRN2

256

Q9H000
DHLYSCLFGTFLCNC

MTMR1

531

Q13613
LSFCGSLEINHFYCA

OR5M10

166

Q6IEU7
YLEHSAACLPCFCFG

HSPG2

511

P98160
VSQLFFYHFLGCTEC

OR10D4P

96

Q8NGN7
CLHTCSRYHFFCDDG

LRP11

306

Q86VZ4
SRYHFFCDDGCCIDI

LRP11

311

Q86VZ4
NLYHDTCFTCAACSR

LIMD1

491

Q9UGP4
EGCLACATAYFIFLC

GOLGA7B

76

Q2TAP0
FCDGCDDNYHIFCLL

KDM5D

331

Q9BY66
FVFYNCSVHQSCLSC

PLXNA1

656

Q9UIW2
FKFYNCSAHQLCLSC

PLXNA2

651

O75051
FVFYNCSVHNSCLSC

PLXNA4

651

Q9HCM2
FSYCGSREIAHFCCD

OR2M7

166

Q8NG81
CVACGFCSLLYAFSQ

GXYLT1

11

Q4G148
HLYSCLFGTFLCNSE

MTMR2

511

Q13614
AYHLACFACFSCKRQ

LHX6

151

Q9UPM6
LCDGCDDSYHTFCLI

KDM5B

326

Q9UGL1
AFCTCFSHLCVIGLF

OR2A7

236

Q96R45
ACLYPFASCCAHTFS

PAQR6

91

Q6TCH4
DSGYFSDNILCHFCA

SLC25A11

211

Q02978
SRHAFCTDYATGFCC

NID2

496

Q14112
TACGFDFCVLCLCAY

FBXO43

661

Q4G163
DFCVLCLCAYHGSEE

FBXO43

666

Q4G163
LFGDCCLCSFTFYSG

CPLANE1

191

Q9H799
CLCSFTFYSGECLKL

CPLANE1

196

Q9H799
GHYNSCYLDSTLFCL

CYLD

596

Q9NQC7
LHLEFCSDYESFGCC

HHIPL2

56

Q6UWX4
RCFNSYGTFLCRCHQ

EFEMP2

216

O95967
FNFLSACCCYLGLAF

SLC39A14

401

Q15043
LNLYFHIQCFRCGIC

LIMCH1

1031

Q9UPQ0
SSCLCNALAHYAYLC

OTOGL

711

Q3ZCN5
HSLCSAFGLQCCLLF

MUCL3

6

Q3MIW9
TFHTCCDVAFCYSSL

TAAR6

106

Q96RI8
CDVAFCYSSLFHLCF

TAAR6

111

Q96RI8
LSFCGSLEINHFYCA

OR5M1

166

Q8NGP8
CSFRYGLSFLVHCCN

SLC17A1

16

Q14916
CFATHVCFCFGSYVT

STS

481

P08842
YCCSVAVFFCFGTTH

MYCBP2

4601

O75592
CFGFQCHEAAVSIYC

SLC38A8

226

A6NNN8
LSYCGSNIINHFFCE

OR5AR1

166

Q8NGP9
AACHSLANAFYCQCL

NOTCH4

1021

Q99466
VHVACCCGNIFSYLF

CLCN3

286

P51790
QAQCGHRYCSFCLAS

TRAF2

46

Q12933
SCNFAFCTLCRLTYH

RNF14

331

Q9UBS8
CSLCGWLSLYISFCH

TLCD5

11

Q6ZRR5
NRLHSCLYCVFFGCF

USP22

71

Q9UPT9
FACDYCSFTCLSKGH

ZFAT

326

Q9P243
SCHYCSCPAFAFSVL

ZSWIM7

81

Q19AV6
YHNNCYRDCIALCFL

SLC6A13

306

Q9NSD5
LCQFQYICSCLHSGL

PIK3CD

256

O00329
GRIFSCSFCHNFLCE

ZNF330

141

Q9Y3S2
SCSCYFNQAFHLPCR

ZSWIM1

381

Q9BR11
HLKCFAASGLEFDCY

USP1

531

O94782
LCDGCDDNYHIFCLL

KDM5C

341

P41229
RCCDCSASLSHQYYE

LIMK1

51

P53667