Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionzinc ion transmembrane transporter activity

SLC39A6 SLC39A7

1.07e-0424132GO:0005385
GeneOntologyMolecularFunctiontransition metal ion transmembrane transporter activity

SLC39A6 SLC39A7

3.64e-0444132GO:0046915
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF281 POU3F3 OTX1 MAFA ZIC3

7.86e-041244135GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF281 POU3F3 OTX1 MAFA ZIC3

8.67e-041271135GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF281 POU3F3 OTX1 MAFA ZIC3

1.40e-031412135GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF281 POU3F3 OTX1 MAFA ZIC3

1.62e-031459135GO:0000977
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

OTX1 MAFA ZIC3

5.09e-03560133GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

OTX1 MAFA ZIC3

5.24e-03566133GO:0001216
GeneOntologyBiologicalProcesszinc ion transmembrane transport

SLC39A6 SLC39A7

1.47e-0429132GO:0071577
GeneOntologyBiologicalProcesszinc ion transport

SLC39A6 SLC39A7

1.58e-0430132GO:0006829
GeneOntologyBiologicalProcessintracellular zinc ion homeostasis

SLC39A6 SLC39A7

3.42e-0444132GO:0006882
GeneOntologyBiologicalProcessmRNA transcription by RNA polymerase II

TAF2 ZIC3

4.78e-0452132GO:0042789
GeneOntologyBiologicalProcessmRNA transcription

TAF2 ZIC3

5.74e-0457132GO:0009299
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

POU3F3 OTX1 TAF2 MAFA ZIC3

1.12e-031390135GO:0045944
GeneOntologyBiologicalProcessbrain development

SELENOP POU3F3 OTX1 ZIC3

1.58e-03859134GO:0007420
GeneOntologyBiologicalProcesshead development

SELENOP POU3F3 OTX1 ZIC3

2.03e-03919134GO:0060322
GeneOntologyBiologicalProcesstransition metal ion transport

SLC39A6 SLC39A7

2.23e-03113132GO:0000041
GeneOntologyBiologicalProcesspeptidyl-threonine phosphorylation

DYRK1A NLK

2.31e-03115132GO:0018107
MousePhenodecreased superior colliculus size

DYRK1A OTX1

8.43e-066112MP:0002892
MousePhenoabnormal cerebral cortex morphology

DYRK1A POU3F3 OTX1 ZIC3

8.62e-05328114MP:0000788
MousePhenoabnormal hippocampus morphology

DYRK1A POU3F3 OTX1 ZIC3

8.93e-05331114MP:0000807
MousePhenoabnormal temporal lobe morphology

DYRK1A POU3F3 OTX1 ZIC3

9.58e-05337114MP:0000801
MousePhenoabnormal superior colliculus morphology

DYRK1A OTX1

1.17e-0421112MP:0000904
MousePhenodecreased midbrain size

DYRK1A OTX1

1.41e-0423112MP:0012089
MousePhenoabnormal limbic system morphology

DYRK1A POU3F3 OTX1 ZIC3

1.49e-04378114MP:0004166
MousePhenoabnormal midbrain morphology

DYRK1A OTX1 ZIC3

1.91e-04151113MP:0000897
MousePhenoabnormal midbrain size

DYRK1A OTX1

2.59e-0431112MP:0012088
MousePhenoabnormal tectum morphology

DYRK1A OTX1

3.30e-0435112MP:0006104
MousePhenoabnormal midbrain roof plate morphology

DYRK1A OTX1

3.30e-0435112MP:0006103
MousePhenoabnormal corpora quadrigemina morphology

DYRK1A OTX1

3.30e-0435112MP:0000899
MousePhenoabnormal zygomatic bone morphology

POU3F3 ZIC3

4.54e-0441112MP:0005270
MousePhenosmall hippocampus

DYRK1A OTX1

5.72e-0446112MP:0008283
MousePhenoabnormal brainstem morphology

DYRK1A OTX1 ZIC3

6.33e-04227113MP:0005277
MousePhenoabnormal thalamus morphology

DYRK1A ZIC3

7.88e-0454112MP:0000832
MousePhenoabnormal hippocampus size

DYRK1A OTX1

8.17e-0455112MP:0008281
MousePhenoabnormal cerebral hemisphere morphology

DYRK1A POU3F3 OTX1 ZIC3

8.65e-04599114MP:0008540
MousePhenoabnormal neurocranium morphology

POU3F3 OTX1 ZIC3

1.04e-03269113MP:0000074
MousePhenoabnormal cerebellum lobule morphology

OTX1 ZIC3

1.28e-0369112MP:0009964
MousePhenopostnatal lethality, incomplete penetrance

DYRK1A SELENOP OTX1 ZIC3

1.31e-03669114MP:0011086
MousePhenoabnormal diencephalon morphology

DYRK1A OTX1 ZIC3

1.39e-03298113MP:0000830
MousePhenoshort tail

SELENOP ZIC3

2.17e-0390112MP:0000592
MousePhenoabnormal telencephalon morphology

DYRK1A POU3F3 OTX1 ZIC3

2.68e-03812114MP:0000787
MousePhenodecreased brain weight

DYRK1A OTX1

3.00e-03106112MP:0002175
MousePhenoabnormal tail length

SELENOP ZIC3

3.00e-03106112MP:0011999
DomainZip

SLC39A6 SLC39A7

4.05e-0514132PF02535
DomainZIP

SLC39A6 SLC39A7

4.05e-0514132IPR003689
DomainHomeobox_CS

POU3F3 OTX1

7.16e-03186132IPR017970
DomainHomeobox

POU3F3 OTX1

1.11e-02234132PF00046
DomainHOMEOBOX_1

POU3F3 OTX1

1.13e-02236132PS00027
DomainHOX

POU3F3 OTX1

1.14e-02237132SM00389
DomainHomeobox_dom

POU3F3 OTX1

1.16e-02239132IPR001356
DomainHOMEOBOX_2

POU3F3 OTX1

1.16e-02239132PS50071
Domain-

POU3F3 OTX1

1.60e-022831321.10.10.60
DomainHomeodomain-like

POU3F3 OTX1

2.16e-02332132IPR009057
DomainSer/Thr_kinase_AS

DYRK1A NLK

2.47e-02357132IPR008271
DomainS_TKc

DYRK1A NLK

2.50e-02359132SM00220
DomainPROTEIN_KINASE_ST

DYRK1A NLK

2.54e-02362132PS00108
DomainProtein_kinase_ATP_BS

DYRK1A NLK

2.76e-02379132IPR017441
DomainPkinase

DYRK1A NLK

2.79e-02381132PF00069
PathwayREACTOME_ZINC_INFLUX_INTO_CELLS_BY_THE_SLC39_GENE_FAMILY

SLC39A6 SLC39A7

1.85e-058122MM15106
PathwayREACTOME_ZINC_INFLUX_INTO_CELLS_BY_THE_SLC39_GENE_FAMILY

SLC39A6 SLC39A7

2.98e-0510122M27361
PathwayREACTOME_ZINC_TRANSPORTERS

SLC39A6 SLC39A7

3.64e-0511122MM15101
PathwayREACTOME_ZINC_TRANSPORTERS

SLC39A6 SLC39A7

6.93e-0515122M832
PathwayREACTOME_METAL_ION_SLC_TRANSPORTERS

SLC39A6 SLC39A7

1.25e-0420122MM15077
PathwayREACTOME_METAL_ION_SLC_TRANSPORTERS

SLC39A6 SLC39A7

1.81e-0424122M18795
PathwayWP_ENDODERM_DIFFERENTIATION

ZNF281 NLK ZIC3

2.10e-04143123M39591
PathwayWP_MESODERMAL_COMMITMENT_PATHWAY

ZNF281 NLK ZIC3

2.57e-04153123M39546
PathwayWP_ZINC_HOMEOSTASIS

SLC39A6 SLC39A7

4.35e-0437122M39377
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC39A6 SLC39A7

1.83e-0376122MM15072
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC39A6 SLC39A7

2.23e-0384122M27334
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

DYRK1A ZNF281 SLC39A6 ERC2 POU3F3 SLC39A7 OTX1 NLK TAF2 MAFA ZIC3

5.94e-151203131129180619
Pubmed

Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells.

POU3F3 OTX1 ZIC3

1.06e-072613322992956
Pubmed

Characterization of Zinc Influx Transporters (ZIPs) in Pancreatic β Cells: ROLES IN REGULATING CYTOSOLIC ZINC HOMEOSTASIS AND INSULIN SECRETION.

SLC39A6 SLC39A7

1.29e-07213225969539
Pubmed

Ermelin, an endoplasmic reticulum transmembrane protein, contains the novel HELP domain conserved in eukaryotes.

SLC39A6 SLC39A7

1.29e-07213211891044
Pubmed

The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor.

SLC39A6 RHOBTB2 TAF2

2.21e-073313319336002
Pubmed

Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters.

SLC39A6 SLC39A7

7.74e-07413212839489
Pubmed

Deletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function.

POU3F3 OTX1

1.00e-051313218596172
Pubmed

Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.

DYRK1A ZNF281 TAF2

2.27e-0515213316009940
Pubmed

Transcriptional regulation of cortical neuron migration by POU domain factors.

POU3F3 OTX1

2.44e-052013211859196
Pubmed

Tbx2 and Tbx3 regulate cell fate progression of the otic vesicle for inner ear development.

POU3F3 OTX1

3.25e-052313236521641
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

ZNF281 OTX1 MAFA ZIC3

3.78e-0554413428473536
Pubmed

Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient.

DYRK1A ZIC3

2.03e-045713234671097
Pubmed

Global phosphoproteome of HT-29 human colon adenocarcinoma cells.

SLC39A7 TAF2

2.18e-045913216083285
Pubmed

A census of human transcription factors: function, expression and evolution.

ZNF281 POU3F3 OTX1 MAFA

2.73e-0490813419274049
InteractionRNF4 interactions

DYRK1A ZNF281 SLC39A6 ERC2 POU3F3 SLC39A7 OTX1 NLK TAF2 MAFA ZIC3

1.32e-1114121311int:RNF4
InteractionKDM5B interactions

SLC39A6 RHOBTB2 TAF2

3.27e-05100133int:KDM5B
InteractionMYB interactions

ZNF281 ERC2 NLK

7.66e-05133133int:MYB
InteractionDBN1 interactions

DYRK1A RHOBTB2 MAFA ZIC3

1.11e-04417134int:DBN1
CytobandEnsembl 112 genes in cytogenetic band chr8q24

TAF2 MAFA

4.40e-03355132chr8q24
GeneFamilySolute carriers

SLC39A6 SLC39A7

1.55e-0239592752
ToppCelldroplet-Tongue-Unstain-18m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYRK1A RHOBTB2

6.62e-04133132f7d0763b5eec2db33044d6850fd57462494038c1
ToppCellmetastatic_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

ERC2 POU3F3

8.30e-0414913204c696f5102b0fff7d80e0f8d12a3119b2b81898
ToppCellClub_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

SLC39A6 OTX1

8.74e-0415313277030b0e033f3635b1bbe7552a28c074ea7bb106
ToppCellControl-PLT_4|World / Disease Group and Platelet Clusters

NLK MAFA

8.86e-04154132a2a03c5e6759c45aeeedf1e68ecb5a0112ef9a20
ToppCell10x5'-Liver-Myeloid_Mac-Intestinal_macrophages|Liver / Manually curated celltypes from each tissue

ERC2 SELENOP

9.09e-041561329a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SELENOP MAFA

9.09e-04156132ea9223bb6450b22df11efa1705ab72dab005244a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SELENOP MAFA

9.09e-04156132586b5509074c4cc359e9e31a968c2ded71c994ca
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OTX1 RHOBTB2

9.91e-041631327af3d3ae7e0de733a18d0486c7ffbb5a7ef7230a
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SELENOP ZIC3

1.00e-03164132ec68954fc09b6850273b5e59caa6b09d02151097
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SELENOP ZIC3

1.00e-031641326a41a159134e605b80d5e731f9ed5bc803bb531b
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SELENOP ZIC3

1.03e-0316613227af6c906cff1d40d134f0386db7708869691121
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OTX1 MAFA

1.05e-031681320f736d58cb0ff042fa3ce58e36bde37b6976f8fc
ToppCell3'_v3-bone_marrow-Mast-Mast_cell_lympho|bone_marrow / Manually curated celltypes from each tissue

NLK TAF2

1.08e-031701324dedf482cd4521b3f87d2b5ae80f7a3ea8686a15
ToppCellNasal_Brush-Epithelial-Ionocytes|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

RHOBTB2 MAFA

1.10e-03172132dd3a23dc78dc6939f41126f8d7bd23a2e4713647
ToppCellNasal_Brush-Epithelial-Ionocytes|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

RHOBTB2 MAFA

1.10e-0317213204fabb40fa9357d8902f3b04adc15231626cd9f8
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERC2 POU3F3

1.13e-03174132271c51d220842402975d97c86c9acfdbdf62a32c
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POU3F3 ZIC3

1.17e-031771326f3b254e56e722cc23495b49e99a4abce0243cb3
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYRK1A RHOBTB2

1.18e-0317813209d2687e0d79f12e90af35fc1c0453d249cf2d19
ToppCell390C-Epithelial_cells-Epithelial-B_(AT2)|390C / Donor, Lineage, Cell class and subclass (all cells)

SELENOP RHOBTB2

1.19e-03179132466da2bc3bfc534ffe111c8c28ece7a3cfa08051
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-pDC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC39A6 OTX1

1.19e-03179132bbd4f8e988ef3f343aaedbc992b70f2bb6aff5f6
ToppCellCOVID-19-Epithelial_cells-AT1|COVID-19 / group, cell type (main and fine annotations)

ERC2 RHOBTB2

1.19e-03179132a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERC2 POU3F3

1.19e-03179132b8ca29aebd25ebac441bebd769bbf98c536d3166
ToppCell390C-Epithelial_cells-Epithelial-B_(AT2)-|390C / Donor, Lineage, Cell class and subclass (all cells)

SELENOP RHOBTB2

1.19e-03179132f4bdebb77d39e63160fbf3a85a340ce4d52b7cfd
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Erythrophagocytic_macrophages|bone_marrow / Manually curated celltypes from each tissue

SLC39A6 SELENOP

1.21e-03180132daf69a548ed7c6f285a6adcff00f99aa22f9d6a5
ToppCellAT2_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

SELENOP RHOBTB2

1.22e-03181132ed0ea67f0607073aedf153f8d1073b35e46127c3
ToppCellfacs-Spleen-nan-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF281 SELENOP

1.26e-03184132c37c623c4a5ff1628486d8a6461fa355ad5c264c
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POU3F3 ZIC3

1.26e-031841327712f2e1fae5cdde2d4e355b860dc8536b28e4f6
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SLC39A6 SLC39A7

1.29e-0318613274c238759c5d3fd39127ec0060d0c2cb16b326d4
ToppCellnormal_Lung-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

POU3F3 OTX1

1.29e-0318613200ad1239b952119b3fd2e6af8f034cba3488f9c1
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SLC39A6 SLC39A7

1.30e-03187132816d37a70f7ec382a268fe828b3dfe737a36a4bf
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.30e-031871327c44cec1c26ca5907a495f2d7e633410e2e9728f
ToppCellMesenchymal-chondrocyte|World / Lineage, Cell type, age group and donor

SELENOP POU3F3

1.31e-031881327b1e3f8a941eaa68e89c562129a92314642eec66
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.33e-03189132da014519d6eb21bc2dc2ed65eafe638b42a068ed
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERC2 NLK

1.33e-03189132a75226616340045b581d08429d2e123e041dee55
ToppCellAT2_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

SELENOP RHOBTB2

1.34e-0319013246dfab02c1b4a403b7efc871707b6a189eefd4c4
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERC2 NLK

1.34e-0319013249e09cdb843b3d889a06a811aa5affae68b25a75
ToppCell(7)_Epithelial-D_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SELENOP RHOBTB2

1.34e-03190132832d6d3ad14665e50623afe1b8586ccae1a97de5
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.36e-031911322b0d55a8e1b4ce862dd038f8e0429e8428fb8aba
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.36e-031911321c46f4eabc1fd790069d5d8b29580d3904e2ef41
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.36e-031911326cb2c107bc674aa173b4009f320a1687a76f3979
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-RGCs_early_2|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

SELENOP ZIC3

1.36e-0319113206107849463a1ccb78a5ccd3ae31619ef6bedda3
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.36e-03191132f00d6824bd138b192a996e9f7de57b235bb24c18
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_memory|lymph-node_spleen / Manually curated celltypes from each tissue

POU3F3 RHOBTB2

1.36e-03191132c3ca8077da8594fb493e47ac4dfbbd20bfc14b37
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.37e-031921325795ad6605565ce194341d08c65aae4b526dac84
ToppCellEndothelial-Endothelial-B|Endothelial / shred on cell class and cell subclass (v4)

SLC39A6 SELENOP

1.37e-03192132f8d7bd81e031d09a557722627c2f6180811cc6ab
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERC2 MAFA

1.37e-031921325b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.38e-031931328646e573f2d2ff175f3d02bfdf214e65f3b614d3
ToppCellAT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

SELENOP RHOBTB2

1.38e-031931328187f976fd2d11fad3286690f1a046e894772220
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.38e-03193132ba484fa1f290a92ae02475a4c468b4ac840c133e
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.38e-03193132043dd0fc2f93e0bd1ca34ac3e196622b3e91df0f
ToppCell(7)_Epithelial_cells|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SELENOP RHOBTB2

1.40e-03194132413e8b9f1e15be363a7f4a8f727af3eeb9e9a928
ToppCell343B-Epithelial_cells-Epithelial-D_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SELENOP RHOBTB2

1.40e-031941323944b00a64428579874e1ebd94ef35a294017658
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.40e-0319413246266d3d9af7000dc1381b1c8e55047193cbcf94
ToppCell343B-Epithelial_cells-Epithelial-D_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

SELENOP RHOBTB2

1.40e-031941325af1f0ca4c46d9368e5defe33b30c7b4382202bb
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.40e-031941320db439a544cf8f918a77058fd70319ab0e8e645e
ToppCell390C-Epithelial_cells-Epithelial-C_(AT2)|390C / Donor, Lineage, Cell class and subclass (all cells)

SELENOP RHOBTB2

1.41e-03195132d0608db4a61576e67f4a3a52e1f84d788a1dea85
ToppCell356C-Epithelial_cells|356C / Donor, Lineage, Cell class and subclass (all cells)

SELENOP RHOBTB2

1.41e-03195132d913d0a6c4797d9a873ddea6f340c3f152da1cf3
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT2-AT2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SELENOP RHOBTB2

1.41e-031951326867f9c56ea27a17c8c4099aae0d79903c3748a5
ToppCell390C-Epithelial_cells-Epithelial-C_(AT2)-|390C / Donor, Lineage, Cell class and subclass (all cells)

SELENOP RHOBTB2

1.41e-03195132bdfe486d32cb598950c1a5f5cdab40302c8f0f99
ToppCellAT2_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

SELENOP RHOBTB2

1.41e-0319513233f60762f00cd6f4757d8a8d5227141558ac823e
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SELENOP RHOBTB2

1.41e-03195132955a0a7244cd7eaf006a39e1bd03333baf6f30a4
ToppCell343B|World / Donor, Lineage, Cell class and subclass (all cells)

SELENOP RHOBTB2

1.41e-031951322290911fde6efacfa38b985a2541322968bee42d
ToppCellAT2_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

SELENOP RHOBTB2

1.41e-031951320792c1e959e933b10ae987d821ff43020dfdabad
ToppCell3'-Parenchyma_lung-Epithelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.41e-03195132eec187c087e432417bc346c5d3ead72f58bf3215
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.41e-03195132d9694db6bf239636d1335016878c98f6ee2eb0eb
ToppCellAT2_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

SELENOP RHOBTB2

1.41e-03195132b0cea3f4e59635913d243612f2e8cf4c7b34e726
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.41e-031951323e24570def013d5b0b1ef1d7a5ced7dfd922590b
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.41e-031951326617abca0009ad3d8731f515f91ab275f9ea4c40
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.41e-03195132fc0ae145a2118df7cbbc9ac4ca9dc12d26c087c4
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.43e-03196132b1abecc0aafc09ca70a5fde624f2a998c4aa3341
ToppCell(7)_Epithelial-B_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SELENOP RHOBTB2

1.43e-03196132345d4cc062b43bca9d506fbf23363469a9ba496f
ToppCellASK440-Epithelial-Type_2|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

SELENOP RHOBTB2

1.43e-03196132754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCellcritical-Epithelial-Secretory|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SELENOP OTX1

1.43e-031961327da687eb983a54c28ee990424cc52e01caf5f4aa
ToppCell356C-Epithelial_cells-Epithelial-A_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

SELENOP RHOBTB2

1.43e-031961324715f19f844e7244fc4bc446cba7c8088c600fc3
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.43e-0319613265e161fd672e37a5d10f28011bb422c4d7042d6a
ToppCellcellseq-Epithelial-Epithelial_Alveolar|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SELENOP RHOBTB2

1.43e-03196132a7cbe66ebd8931ef2b8ff26a42afce0ad1c48f17
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.43e-03196132006d783a530aa6e1e6545dcc2e6b00bb300fe070
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.43e-031961327e5addaa844e66f8160e05858c341866a80aed23
ToppCell356C-Epithelial_cells-Epithelial-A_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

SELENOP RHOBTB2

1.43e-0319613293a5d9b8bcff7d07596ef1f4f2b74f043835fc69
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.43e-031961329d267dd293fde05f04febc0a9d15776c5b782a1c
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.43e-0319613282b117be41f2e7d677a42d2a5198726eeccb16d0
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.43e-0319613283aeb96a33802949238d8a097086a1812201d1b5
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.43e-0319613269f27c2668a9f412b2eb6ca83d11b44863209542
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.44e-031971320d59a2669de60046e8140d82e67c2b5da4a5683c
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.44e-03197132d2a4d7e92e91bcc47a7657da2e5c8a3ad7eb08ad
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.44e-03197132bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCellBronchus_Control_(B.)|World / Sample group, Lineage and Cell type

OTX1 MAFA

1.44e-03197132b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCellASK440-Epithelial-Type_2|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

SELENOP RHOBTB2

1.44e-0319713208d5bbeb77a4152af1c783bc958afcae24667767
ToppCell343B-Epithelial_cells-Epithelial-B_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

SELENOP RHOBTB2

1.44e-03197132f3ca63c7902d7530a29a85eb54f69b303031d150
ToppCell356C-Epithelial_cells-Epithelial-B_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

SELENOP RHOBTB2

1.44e-0319713206ed8f293d4ee89f14dc2f43d6cae93bbc02508a
ToppCellNS-critical-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SELENOP OTX1

1.44e-03197132a72047b7428c0d4aaf016c1ac23dc30919260fd8
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ERC2 ZIC3

1.44e-031971328f009a15f154b3bb184b489da4722b7c27de7e11
ToppCell5'-Parenchyma_lung-Epithelial|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.44e-0319713264d7411f1b3df4f7beeddcde367bfea366878be0
ToppCell343B-Epithelial_cells-Epithelial-B_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SELENOP RHOBTB2

1.44e-03197132f98720cab066579fdac3ba24fb6fe4c5759dae4e
ToppCell356C-Epithelial_cells-Epithelial-B_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

SELENOP RHOBTB2

1.44e-03197132c115d0a45545ed24259ad88872231bf4d4d389d2
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.44e-03197132dea31a839de5386d6b7ead1281a6ea6b0596a855
ToppCell390C-Epithelial_cells|390C / Donor, Lineage, Cell class and subclass (all cells)

SELENOP RHOBTB2

1.44e-0319713278554b26b04752e7cd80402c93a3a491560e8f5f
ToppCellEpithelial_cells-AT2_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

SELENOP RHOBTB2

1.44e-0319713259aa28a377315dfcda4d9b6ecd3419157654f24e
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELENOP RHOBTB2

1.44e-0319713287c4eafe46f622f9830df75e1ca589e064651db4
ToppCellAT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

SELENOP RHOBTB2

1.46e-03198132893036558a9ad86b57f9e735df35812e9d18739e
DiseaseIntellectual Disability

POU3F3 RHOBTB2 TAF2

8.82e-04447133C3714756
DiseaseGlobal developmental delay

POU3F3 RHOBTB2

1.52e-03133132C0557874

Protein segments in the cluster

PeptideGeneStartEntry
NALHHHHGNSSHHHH

DYRK1A

596

Q13627
HHHHHHHHHGQQALG

DYRK1A

611

Q13627
HGAHHAAHHHHAAHH

MAFA

186

Q8NHW3
YDDDHHHYHHHHHHH

ERC2

916

O15083
SAAAAGHHHHHHHHL

NLK

21

Q9UBE8
LSQSSGHHHHHHHHH

OTX1

286

P32242
ELAEHHHHHHHHAHP

POU3F3

266

P20264
SKHSDHHHHHHHEHK

TAF2

1141

Q6P1X5
GHSDQHHHHHHHHHG

RHOBTB2

321

Q9BYZ6
HHEHHHNHGHQHLGS

SELENOP

206

P49908
HIHHDHDHHSDHEHH

SLC39A6

91

Q13433
HDHHSDHEHHSDHER

SLC39A6

96

Q13433
HSDHEHHSEHEHHSD

SLC39A6

111

Q13433
HHSEHEHHSDHDHHS

SLC39A6

116

Q13433
EHHSDHDHHSHHNHA

SLC39A6

121

Q13433
YANALGHHHHHHHHH

ZIC3

81

O60481
THDHDHGHSHEDLHH

SLC39A7

76

Q92504
EEQQSHHHHHHHHYG

ZNF281

136

Q9Y2X9