Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	metalloendopeptidase activity	TRABD2A ADAMTS12 MMP24 ADAM17 MMP8 MMP11 MMP17	3.77e-06	120	107	7	GO:0004222
GeneOntologyMolecularFunction	cell adhesion molecule binding	FN1 CALR LARP1 RDX TENM2 PPL MSN MMP24 PTPRM ANGPTL3 TENM1 PRKCA ADAM17 GPNMB	3.84e-06	599	107	14	GO:0050839
GeneOntologyMolecularFunction	metallopeptidase activity	TRABD2A ERAP1 ADAMTS12 MMP24 ADAM17 MMP8 MMP11 MMP17	1.23e-05	200	107	8	GO:0008237
GeneOntologyMolecularFunction	transition metal ion binding	CYP2A13 FN1 MARCHF10 L3MBTL2 TNFSF10 ERAP1 CALR PIAS4 MMP24 SETDB1 MIB1 PRKCA ENDOU MMP8 MMP11 MMP17 PLOD2 ALOX5 ALOX15	1.66e-05	1189	107	19	GO:0046914
GeneOntologyMolecularFunction	proteoglycan binding	FN1 FCN2 NID1 GPNMB	1.60e-04	51	107	4	GO:0043394
GeneOntologyMolecularFunction	arachidonate 12(S)-lipoxygenase activity	ALOX5 ALOX15	1.69e-04	4	107	2	GO:0004052
GeneOntologyMolecularFunction	dioxygenase activity	PLOD2 KDM6A UTY ALOX5 ALOX15	1.84e-04	98	107	5	GO:0051213
GeneOntologyMolecularFunction	peptidase activity	TRABD2A ERAP1 ADAMTS12 USP26 MMP24 ENDOU USP4 ADAM17 MMP8 MMP11 MMP17 PCSK4	2.00e-04	654	107	12	GO:0008233
GeneOntologyMolecularFunction	histone H3K27me2/H3K27me3 demethylase activity	KDM6A UTY	2.81e-04	5	107	2	GO:0071558
GeneOntologyMolecularFunction	integrin binding	FN1 CALR ANGPTL3 PRKCA ADAM17 GPNMB	3.62e-04	175	107	6	GO:0005178
GeneOntologyMolecularFunction	endopeptidase activity	TRABD2A ERAP1 ADAMTS12 MMP24 ADAM17 MMP8 MMP11 MMP17 PCSK4	5.11e-04	430	107	9	GO:0004175
GeneOntologyMolecularFunction	interleukin-6 receptor binding	ERAP1 ADAM17	5.87e-04	7	107	2	GO:0005138
GeneOntologyMolecularFunction	tumor necrosis factor binding	ADAM17 MMP8	5.87e-04	7	107	2	GO:0043120
GeneOntologyMolecularFunction	ADP phosphatase activity	ENTPD1 ENTPD2	5.87e-04	7	107	2	GO:0043262
GeneOntologyMolecularFunction	adenosine receptor binding	GRM5 USP4	7.80e-04	8	107	2	GO:0031685
GeneOntologyMolecularFunction	phospholipase D activity	PLD3 PLD1	7.80e-04	8	107	2	GO:0004630
GeneOntologyMolecularFunction	zinc ion binding	MARCHF10 L3MBTL2 TNFSF10 ERAP1 CALR PIAS4 MMP24 SETDB1 MIB1 PRKCA MMP8 MMP11 MMP17	9.55e-04	891	107	13	GO:0008270
GeneOntologyMolecularFunction	phosphatidylserine floppase activity	ABCA1 ATP8A1	9.99e-04	9	107	2	GO:0090556
GeneOntologyMolecularFunction	UDP phosphatase activity	ENTPD1 ENTPD2	9.99e-04	9	107	2	GO:0045134
GeneOntologyMolecularFunction	carbohydrate binding	CALR ZG16B H6PD CLEC4F FCN2 ENDOU PLOD2	1.41e-03	310	107	7	GO:0030246
GeneOntologyMolecularFunction	sulfur compound binding	ACACA FN1 RYR2 NRP2 ANGPTL3 TENM1 GPNMB	1.78e-03	323	107	7	GO:1901681
GeneOntologyMolecularFunction	GDP phosphatase activity	ENTPD1 ENTPD2	1.81e-03	12	107	2	GO:0004382
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	TMC2 CACNA1G CACNA2D3	1.92e-03	46	107	3	GO:0005245
GeneOntologyMolecularFunction	iron ion binding	CYP2A13 CALR PLOD2 ALOX5 ALOX15	2.01e-03	166	107	5	GO:0005506
GeneOntologyCellularComponent	extracellular matrix	COL4A2 FN1 CALR ADAMTS12 MMP24 ORM2 FCN2 ENTPD1 ENTPD2 ANGPTL3 NID1 MMP8 MMP11 MMP17 MUC4	1.79e-06	656	110	15	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL4A2 FN1 CALR ADAMTS12 MMP24 ORM2 FCN2 ENTPD1 ENTPD2 ANGPTL3 NID1 MMP8 MMP11 MMP17 MUC4	1.86e-06	658	110	15	GO:0030312
GeneOntologyCellularComponent	apical plasma membrane	SLC2A9 FN1 SLC6A19 RDX LCT MSN SLC7A5 ADAM17 PLD1 ATP12A MUC4	5.25e-05	487	110	11	GO:0016324
GeneOntologyCellularComponent	apical part of cell	SLC2A9 FN1 SLC6A19 RDX LCT MSN PRKCA SLC7A5 ADAM17 PLD1 ATP12A MUC4	6.70e-05	592	110	12	GO:0045177
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL4A2 FN1 CALR ORM2 FCN2 ENTPD1 ENTPD2 ANGPTL3 NID1 MMP8 MUC4	1.11e-04	530	110	11	GO:0062023
GeneOntologyCellularComponent	Mon1-Ccz1 complex	CCZ1B CCZ1	2.72e-04	5	110	2	GO:0035658
GeneOntologyCellularComponent	endoplasmic reticulum lumen	COL4A2 FN1 ERAP1 CALR CALU H6PD ADAM17 PCSK4	3.74e-04	332	110	8	GO:0005788
GeneOntologyCellularComponent	TORC1 complex	LARP1 MTOR	4.06e-04	6	110	2	GO:0031931
GeneOntologyCellularComponent	external side of apical plasma membrane	LCT SLC7A5	4.06e-04	6	110	2	GO:0098591
GeneOntologyCellularComponent	basement membrane	COL4A2 FN1 ENTPD1 ENTPD2 NID1	4.68e-04	122	110	5	GO:0005604
GeneOntologyCellularComponent	nuclear matrix	TEP1 PIAS4 TENM1 STAG2 ALOX5	8.74e-04	140	110	5	GO:0016363
GeneOntologyCellularComponent	sarcoplasmic reticulum lumen	CALR CALU	9.64e-04	9	110	2	GO:0033018
GeneOntologyCellularComponent	vacuole	RAB9B CCZ1B CALR PLD3 PLBD2 ORM2 ATP8A1 CCZ1 MTOR SLC7A5 USP4 PLD1 HTT	1.02e-03	913	110	13	GO:0005773
GeneOntologyCellularComponent	microvillus membrane	MSN SLC7A5 MUC4	1.05e-03	38	110	3	GO:0031528
GeneOntologyCellularComponent	lysosome	RAB9B CCZ1B CALR PLD3 PLBD2 ORM2 ATP8A1 CCZ1 MTOR SLC7A5 USP4 PLD1	1.16e-03	811	110	12	GO:0005764
GeneOntologyCellularComponent	lytic vacuole	RAB9B CCZ1B CALR PLD3 PLBD2 ORM2 ATP8A1 CCZ1 MTOR SLC7A5 USP4 PLD1	1.16e-03	811	110	12	GO:0000323
GeneOntologyCellularComponent	endoplasmic reticulum membrane	CYBB CYP2A13 ABCA1 ERAP1 CALR CALU PLCD4 TMEM214 PLD3 RYR2 MTOR ENTPD2 EBP PLD1 PLOD2 POFUT2	1.18e-03	1293	110	16	GO:0005789
GeneOntologyCellularComponent	sarcoplasmic reticulum	CALR CALU H6PD RYR2	1.21e-03	88	110	4	GO:0016529
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	CYBB CYP2A13 ABCA1 ERAP1 CALR CALU PLCD4 TMEM214 PLD3 RYR2 MTOR ENTPD2 EBP PLD1 PLOD2 POFUT2	1.24e-03	1299	110	16	GO:0098827
GeneOntologyCellularComponent	perinuclear region of cytoplasm	CYBB ABCA1 CALR PPP1R13B MSN PTPRM TENM1 PRKCA CACNA1G PLD1 CDC20 ALOX5 HTT	1.25e-03	934	110	13	GO:0048471
GeneOntologyCellularComponent	phagocytic vesicle	CYBB RAB9B ABCA1 CALR MTOR	1.46e-03	157	110	5	GO:0045335
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	CYBB CYP2A13 ABCA1 ERAP1 CALR CALU PLCD4 TMEM214 PLD3 RYR2 MTOR ENTPD2 EBP PLD1 PLOD2 POFUT2	1.55e-03	1327	110	16	GO:0042175
GeneOntologyCellularComponent	specific granule	CYBB ORM2 ATP8A1 PLD1 MMP8	1.58e-03	160	110	5	GO:0042581
GeneOntologyCellularComponent	TOR complex	LARP1 MTOR	1.75e-03	12	110	2	GO:0038201
GeneOntologyCellularComponent	MLL3/4 complex	KDM6A UTY	1.75e-03	12	110	2	GO:0044666
GeneOntologyCellularComponent	nuclear periphery	TEP1 PIAS4 TENM1 STAG2 ALOX5	2.12e-03	171	110	5	GO:0034399
GeneOntologyCellularComponent	sarcoplasm	CALR CALU H6PD RYR2	3.11e-03	114	110	4	GO:0016528
GeneOntologyCellularComponent	actin-based cell projection	TMC2 RDX TENM2 MSN SLC7A5 MUC4	3.54e-03	278	110	6	GO:0098858
GeneOntologyCellularComponent	cell tip	RDX MSN	3.54e-03	17	110	2	GO:0051286
GeneOntologyCellularComponent	microvillus	RDX MSN SLC7A5 MUC4	4.08e-03	123	110	4	GO:0005902
Domain	CYSTEINE_SWITCH	ADAMTS12 MMP24 ADAM17 MMP8 MMP11 MMP17	1.31e-07	41	109	6	PS00546
Domain	Pept_M10_metallopeptidase	ADAMTS12 MMP24 ADAM17 MMP8 MMP11 MMP17	1.76e-07	43	109	6	IPR001818
Domain	ZINC_PROTEASE	ERAP1 ADAMTS12 MMP24 ADAM17 MMP8 MMP11 MMP17	1.70e-06	98	109	7	PS00142
Domain	Pept_M10A_stromelysin-type	MMP24 MMP8 MMP11 MMP17	3.15e-06	18	109	4	IPR016293
Domain	-	ADAMTS12 MMP24 ADAM17 MMP8 MMP11 MMP17	7.82e-06	81	109	6	3.40.390.10
Domain	MetalloPept_cat_dom	ADAMTS12 MMP24 ADAM17 MMP8 MMP11 MMP17	7.82e-06	81	109	6	IPR024079
Domain	Hemopexin-like_dom	MMP24 MMP8 MMP11 MMP17	8.92e-06	23	109	4	IPR000585
Domain	Hemopexin-like_repeat	MMP24 MMP8 MMP11 MMP17	8.92e-06	23	109	4	IPR018487
Domain	HEMOPEXIN	MMP24 MMP8 MMP11 MMP17	8.92e-06	23	109	4	PS00024
Domain	-	MMP24 MMP8 MMP11 MMP17	8.92e-06	23	109	4	2.110.10.10
Domain	HEMOPEXIN_2	MMP24 MMP8 MMP11 MMP17	8.92e-06	23	109	4	PS51642
Domain	HX	MMP24 MMP8 MMP11 MMP17	8.92e-06	23	109	4	SM00120
Domain	M10A_MMP	MMP24 MMP8 MMP11 MMP17	8.92e-06	23	109	4	IPR033739
Domain	Hemopexin	MMP24 MMP8 MMP11 MMP17	8.92e-06	23	109	4	PF00045
Domain	Pept_M10A	MMP24 MMP8 MMP11 MMP17	8.92e-06	23	109	4	IPR021190
Domain	Peptidase_M10	MMP24 MMP8 MMP11 MMP17	1.07e-05	24	109	4	PF00413
Domain	Peptidase_Metallo	MMP24 MMP8 MMP11 MMP17	2.33e-05	29	109	4	IPR006026
Domain	ZnMc	MMP24 MMP8 MMP11 MMP17	2.33e-05	29	109	4	SM00235
Domain	DUF1712	CCZ1B CCZ1	3.37e-05	2	109	2	PF08217
Domain	DUF1712_fun	CCZ1B CCZ1	3.37e-05	2	109	2	IPR013176
Domain	-	LRP1B TENM2 TENM1 NID1	7.71e-05	39	109	4	2.120.10.30
Domain	Hemopexin_CS	MMP24 MMP8 MMP11	1.24e-04	17	109	3	IPR018486
Domain	MAM	NRP2 MALRD1 PTPRM	1.24e-04	17	109	3	SM00137
Domain	EGF-like_CS	FN1 LRP1B TENM2 MALRD1 TENM1 NID1 ADAM17 MUC4	1.47e-04	261	109	8	IPR013032
Domain	MAM	NRP2 MALRD1 PTPRM	1.48e-04	18	109	3	PF00629
Domain	MAM_dom	NRP2 MALRD1 PTPRM	1.48e-04	18	109	3	IPR000998
Domain	MAM_2	NRP2 MALRD1 PTPRM	1.48e-04	18	109	3	PS50060
Domain	6-blade_b-propeller_TolB-like	LRP1B TENM2 TENM1 NID1	1.48e-04	46	109	4	IPR011042
Domain	ERM_C_dom	RDX MSN	2.01e-04	4	109	2	IPR011259
Domain	Tox-GHH_dom	TENM2 TENM1	2.01e-04	4	109	2	IPR028916
Domain	PLDc	PLD3 PLD1	2.01e-04	4	109	2	PF00614
Domain	Tox-GHH	TENM2 TENM1	2.01e-04	4	109	2	PF15636
Domain	Ten_N	TENM2 TENM1	2.01e-04	4	109	2	IPR009471
Domain	Ten_N	TENM2 TENM1	2.01e-04	4	109	2	PF06484
Domain	ERM	RDX MSN	2.01e-04	4	109	2	PF00769
Domain	TENEURIN_N	TENM2 TENM1	2.01e-04	4	109	2	PS51361
Domain	ERM	RDX MSN	2.01e-04	4	109	2	IPR011174
Domain	PG_binding_1	MMP24 MMP8 MMP17	2.05e-04	20	109	3	PF01471
Domain	Peptidoglycan-bd-like	MMP24 MMP8 MMP17	2.05e-04	20	109	3	IPR002477
Domain	Ez/rad/moesin-like	RDX MSN MYLIP	2.38e-04	21	109	3	IPR000798
Domain	NIDO_dom	NID1 MUC4	3.34e-04	5	109	2	IPR003886
Domain	NIDO	NID1 MUC4	3.34e-04	5	109	2	SM00539
Domain	NIDO	NID1 MUC4	3.34e-04	5	109	2	PF06119
Domain	NIDO	NID1 MUC4	3.34e-04	5	109	2	PS51220
Domain	YD	TENM2 TENM1	3.34e-04	5	109	2	IPR006530
Domain	FERM_C	RDX MSN MYLIP	4.56e-04	26	109	3	PF09380
Domain	LipOase_mml	ALOX5 ALOX15	4.99e-04	6	109	2	IPR001885
Domain	LIPOXYGENASE_1	ALOX5 ALOX15	4.99e-04	6	109	2	PS00711
Domain	LipOase_C	ALOX5 ALOX15	4.99e-04	6	109	2	IPR013819
Domain	LIPOXYGENASE_2	ALOX5 ALOX15	4.99e-04	6	109	2	PS00081
Domain	LipOase_Fe_BS	ALOX5 ALOX15	4.99e-04	6	109	2	IPR020833
Domain	LipOase_CS	ALOX5 ALOX15	4.99e-04	6	109	2	IPR020834
Domain	PLDc	PLD3 PLD1	4.99e-04	6	109	2	SM00155
Domain	Lipoxygenase	ALOX5 ALOX15	4.99e-04	6	109	2	PF00305
Domain	LIPOXYGENASE_3	ALOX5 ALOX15	4.99e-04	6	109	2	PS51393
Domain	LipOase	ALOX5 ALOX15	4.99e-04	6	109	2	IPR000907
Domain	FERM_PH-like_C	RDX MSN MYLIP	5.11e-04	27	109	3	IPR018980
Domain	FERM_C	RDX MSN MYLIP	5.11e-04	27	109	3	SM01196
Domain	Moesin_tail	RDX MSN	6.95e-04	7	109	2	IPR008954
Domain	PLipase_D/transphosphatidylase	PLD3 PLD1	6.95e-04	7	109	2	IPR001736
Domain	PLD	PLD3 PLD1	6.95e-04	7	109	2	PS50035
Domain	EGF_1	FN1 LRP1B TENM2 MALRD1 TENM1 NID1 MUC4	7.44e-04	255	109	7	PS00022
Domain	TMC	TMC2 TMC3	9.24e-04	8	109	2	PF07810
Domain	GDA1_CD39_NTPase	ENTPD1 ENTPD2	9.24e-04	8	109	2	IPR000407
Domain	GDA1_CD39	ENTPD1 ENTPD2	9.24e-04	8	109	2	PF01150
Domain	GDA1_CD39_NTPASE	ENTPD1 ENTPD2	9.24e-04	8	109	2	PS01238
Domain	TMC	TMC2 TMC3	9.24e-04	8	109	2	IPR012496
Domain	FERM_N	RDX MSN MYLIP	9.29e-04	33	109	3	IPR018979
Domain	FERM_N	RDX MSN MYLIP	9.29e-04	33	109	3	PF09379
Domain	EF-hand_8	CALU RYR2 KCNIP4	1.01e-03	34	109	3	PF13833
Domain	FERM_M	RDX MSN MYLIP	2.45e-03	46	109	3	PF00373
Domain	NHL	TENM2 TENM1	2.52e-03	13	109	2	PS51125
Domain	EGF	LRP1B TENM2 MALRD1 TENM1 NID1 MUC4	2.57e-03	235	109	6	SM00181
Domain	EGF_3	LRP1B TENM2 MALRD1 TENM1 NID1 MUC4	2.57e-03	235	109	6	PS50026
Domain	-	RDX MSN MYLIP	2.93e-03	49	109	3	1.20.80.10
Domain	FERM_central	RDX MSN MYLIP	2.93e-03	49	109	3	IPR019748
Domain	FERM_domain	RDX MSN MYLIP	2.93e-03	49	109	3	IPR000299
Domain	Ldl_recept_b	LRP1B NID1	2.93e-03	14	109	2	PF00058
Domain	LDLRB	LRP1B NID1	2.93e-03	14	109	2	PS51120
Domain	FERM/acyl-CoA-bd_prot_3-hlx	RDX MSN MYLIP	3.10e-03	50	109	3	IPR014352
Domain	FERM_1	RDX MSN MYLIP	3.10e-03	50	109	3	PS00660
Domain	FERM_2	RDX MSN MYLIP	3.10e-03	50	109	3	PS00661
Domain	FERM_3	RDX MSN MYLIP	3.10e-03	50	109	3	PS50057
Domain	Band_41_domain	RDX MSN MYLIP	3.10e-03	50	109	3	IPR019749
Domain	B41	RDX MSN MYLIP	3.10e-03	50	109	3	SM00295
Domain	LY	LRP1B NID1	3.37e-03	15	109	2	SM00135
Domain	Pept_M10A_Zn_BS	MMP8 MMP11	3.37e-03	15	109	2	IPR021158
Domain	LDLR_classB_rpt	LRP1B NID1	3.37e-03	15	109	2	IPR000033
Domain	EGF-like_dom	LRP1B TENM2 MALRD1 TENM1 NID1 MUC4	3.41e-03	249	109	6	IPR000742
Domain	EGF_2	LRP1B TENM2 MALRD1 TENM1 NID1 MUC4	4.62e-03	265	109	6	PS01186
Domain	LH2	ALOX5 ALOX15	4.86e-03	18	109	2	SM00308
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL4A2 FN1 MMP24 NID1 ADAM17 MMP8 MMP11 MMP17	3.29e-06	140	91	8	M587
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL4A2 FN1 MMP24 NID1 MMP8 MMP11 MMP17	8.69e-06	114	91	7	MM14571
Pathway	WP_CHRONIC_HYPERGLYCEMIA_IMPAIRMENT_OF_NEURON_FUNCTION	MMP24 PRKCA MMP8 MMP11 MMP17	1.12e-05	46	91	5	M46450
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL4A2 FN1 MMP24 PRKCA NID1 ADAM17 MMP8 MMP11 MMP17 PLOD2	2.30e-05	300	91	10	M610
Pathway	WP_MATRIX_METALLOPROTEINASES	MMP24 MMP8 MMP11 MMP17	3.41e-05	29	91	4	MM15981
Pathway	WP_MATRIX_METALLOPROTEINASES	MMP24 MMP8 MMP11 MMP17	3.92e-05	30	91	4	M39652
Pathway	REACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES	MMP24 MMP8 MMP11 MMP17	5.76e-05	33	91	4	M26976
Pathway	REACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES	MMP24 MMP8 MMP11 MMP17	1.01e-04	38	91	4	MM14611
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL4A2 FN1 MMP24 NID1 MMP8 MMP11 MMP17 PLOD2	2.59e-04	258	91	8	MM14572
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	PLCD4 LRP1B ADAMTS12 PIAS4 MMP24 ATP8A1 ENTPD1 ENTPD2 PRKCA PRMT2 USP4 MMP8 MMP11 MMP17 PCSK4	1.09e-08	730	110	15	34857952
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	ACACA FN1 ERAP1 CALR CALU TMEM214 H6PD PLD3 PLBD2 NRP2 MSN IGF2BP2 EBP NID1 ADAM17 MMP11 PLOD2 POFUT2 ALOX15	1.41e-07	1451	110	19	30550785
Pubmed	Matrix metalloproteinases in tumor invasion.	MMP24 MMP8 MMP11 MMP17	1.67e-07	16	110	4	10949577
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	COL4A2 ERAP1 CALR CALU TMEM214 H6PD PLD3 LRP1B PLBD2 NRP2 EBP NID1 SLC7A5 ADAM17 PLOD2 POFUT2 HTT	2.36e-07	1201	110	17	35696571
Pubmed	Functional interactions between matrix metalloproteinases and glycosaminoglycans.	MMP24 MMP8 MMP11 MMP17	6.63e-07	22	110	4	23421805
Pubmed	Matrix metalloproteinases.	MMP24 MMP8 MMP11 MMP17	6.63e-07	22	110	4	10419448
Pubmed	Human colostrum: identification of minor proteins in the aqueous phase by proteomics.	ERAP1 CALR ZG16B RDX MSN ORM2 MUC4	8.89e-07	162	110	7	16502470
Pubmed	Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).	TNFSF10 ERAP1 CALR ZG16B RDX PLD3 PPL MSN PLOD2 MUC4	8.90e-07	417	110	10	19199708
Pubmed	Matrix metalloproteinases 2 and 9 are dispensable for pancreatic islet formation and function in vivo.	MMP24 MMP8 MMP11 MMP17	9.59e-07	24	110	4	15734845
Pubmed	UTX Affects Neural Stem Cell Proliferation and Differentiation through PTEN Signaling.	MTOR KDM6A UTY	1.07e-06	7	110	3	29551674
Pubmed	Hypoplastic basement membrane of the lens anlage in the inheritable lens aplastic mouse (lap mouse).	COL4A2 FN1 NID1	1.07e-06	7	110	3	10716744
Pubmed	Functional proteomics mapping of a human signaling pathway.	COL4A2 FN1 PPP1R13B PPL RYR2 PIAS4 SETDB1 NID1 GPNMB MMP11 KDM6A	2.91e-06	591	110	11	15231748
Pubmed	Binding of mouse and human fibulin-2 to extracellular matrix ligands.	COL4A2 FN1 NID1	4.99e-06	11	110	3	7500359
Pubmed	Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.	MMP24 MMP8 MMP11 MMP17	5.16e-06	36	110	4	20587546
Pubmed	Matrilin-2 interacts with itself and with other extracellular matrix proteins.	COL4A2 FN1 NID1	6.63e-06	12	110	3	12180907
Pubmed	Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.	COL4A2 FN1 NID1	8.60e-06	13	110	3	9833687
Pubmed	Embryo-uterine interaction coordinates mouse embryogenesis during implantation.	FN1 RDX MSN	8.60e-06	13	110	3	37522872
Pubmed	Expression of UTX Indicates Poor Prognosis in Patients With Luminal Breast Cancer and is Associated With MMP-11 Expression.	MMP11 KDM6A	9.91e-06	2	110	2	31335488
Pubmed	An H-YDb epitope is encoded by a novel mouse Y chromosome gene.	KDM6A UTY	9.91e-06	2	110	2	8944031
Pubmed	Nuclear localization of phospholipase D1 mediates the activation of nuclear protein kinase C(alpha) and extracellular signal-regulated kinase signaling pathways.	PRKCA PLD1	9.91e-06	2	110	2	21113078
Pubmed	PTPRM methylation induced by FN1 promotes the development of glioblastoma by activating STAT3 signalling.	FN1 PTPRM	9.91e-06	2	110	2	34225581
Pubmed	Expression of NTPDase1 and NTPDase2 in murine kidney: relevance to regulation of P2 receptor signaling.	ENTPD1 ENTPD2	9.91e-06	2	110	2	15632415
Pubmed	The Adipose Tissue-Derived Secretome (ADS) in Obesity Uniquely Induces L-Type Amino Acid Transporter 1 (LAT1) and mTOR Signaling in Estrogen-Receptor-Positive Breast Cancer Cells.	MTOR SLC7A5	9.91e-06	2	110	2	34201429
Pubmed	NTPDase1 and -2 are expressed by distinct cellular compartments in the mouse colon and differentially impact colonic physiology and function after DSS colitis.	ENTPD1 ENTPD2	9.91e-06	2	110	2	31188623
Pubmed	Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663.	ALOX5 ALOX15	9.91e-06	2	110	2	22516296
Pubmed	LARP1 post-transcriptionally regulates mTOR and contributes to cancer progression.	LARP1 MTOR	9.91e-06	2	110	2	25531318
Pubmed	Toxoplasma gondii GRA7-Targeted ASC and PLD1 Promote Antibacterial Host Defense via PKCα.	PRKCA PLD1	9.91e-06	2	110	2	28125719
Pubmed	Phospholipase D regulates the size of skeletal muscle cells through the activation of mTOR signaling.	MTOR PLD1	9.91e-06	2	110	2	23915343
Pubmed	Blockade of PLD1 potentiates the antitumor effects of bortezomib in multiple myeloma cells by inhibiting the mTOR/NF-κB signal pathway.	MTOR PLD1	9.91e-06	2	110	2	33191863
Pubmed	GPNMB mitigates Alzheimer's disease and enhances autophagy via suppressing the mTOR signal.	MTOR GPNMB	9.91e-06	2	110	2	34695452
Pubmed	Differential catalytic properties and vascular topography of murine nucleoside triphosphate diphosphohydrolase 1 (NTPDase1) and NTPDase2 have implications for thromboregulation.	ENTPD1 ENTPD2	9.91e-06	2	110	2	11929769
Pubmed	Leukotrienes enhance the bactericidal activity of alveolar macrophages against Klebsiella pneumoniae through the activation of NADPH oxidase.	CYBB ALOX5	9.91e-06	2	110	2	15718414
Pubmed	Role of defective calcium regulation in cardiorespiratory dysfunction in Huntington's disease.	RYR2 HTT	9.91e-06	2	110	2	32897880
Pubmed	αv-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation.	FN1 NID1	9.91e-06	2	110	2	33141174
Pubmed	Morphoproteomic analysis reveals an overexpressed and constitutively activated phospholipase D1-mTORC2 pathway in endometrial carcinoma.	MTOR PLD1	9.91e-06	2	110	2	21228924
Pubmed	Endogenous LXA4 circuits are determinants of pathological angiogenesis in response to chronic injury.	ALOX5 ALOX15	9.91e-06	2	110	2	20008149
Pubmed	Metabotropic glutamate receptor-mediated cell signaling pathways are altered in a mouse model of Huntington's disease.	GRM5 HTT	9.91e-06	2	110	2	20053912
Pubmed	Proteomic and lipidomic profiling of demyelinating lesions identifies fatty acids as modulators in lesion recovery.	ALOX5 ALOX15	9.91e-06	2	110	2	34706241
Pubmed	Protein kinase C alpha associates with phospholipase D1 and enhances basal phospholipase D activity in a protein phosphorylation-independent manner in human melanoma cells.	PRKCA PLD1	9.91e-06	2	110	2	12839565
Pubmed	PLD1 is overexpressed in an ER-negative MCF-7 cell line variant and a subset of phospho-Akt-negative breast carcinomas.	MTOR PLD1	9.91e-06	2	110	2	17726467
Pubmed	Sex-specific differences in expression of histone demethylases Utx and Uty in mouse brain and neurons.	KDM6A UTY	9.91e-06	2	110	2	18434530
Pubmed	Constitutive activation with overexpression of the mTORC2-phospholipase D1 pathway in uterine leiomyosarcoma and STUMP: morphoproteomic analysis with therapeutic implications.	MTOR PLD1	9.91e-06	2	110	2	21326806
Pubmed	Interactive effect between ATPase-related genes and early-life tobacco smoke exposure on bronchial hyper-responsiveness detected in asthma-ascertained families.	ABCA1 ATP8A1	9.91e-06	2	110	2	30282721
Pubmed	The arginylation-dependent association of calreticulin with stress granules is regulated by calcium.	CALR ATE1	9.91e-06	2	110	2	20423325
Pubmed	Ryanodine receptor phosphorylation by oxidized CaMKII contributes to the cardiotoxic effects of cardiac glycosides.	CYBB RYR2	9.91e-06	2	110	2	24104877
Pubmed	The amino acid transporter Slc7a5 regulates the mTOR pathway and is required for granule cell development.	MTOR SLC7A5	9.91e-06	2	110	2	32821949
Pubmed	Human membrane type-4 matrix metalloproteinase (MT4-MMP) is encoded by a novel major transcript: isolation of complementary DNA clones for human and mouse mt4-mmp transcripts.	MMP24 MMP17	9.91e-06	2	110	2	10471807
Pubmed	Target sequencing and CRISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer.	KDM6A UTY	9.91e-06	2	110	2	27533081
Pubmed	Molecular basis for the reduced catalytic activity of the naturally occurring T560M mutant of human 12/15-lipoxygenase that has been implicated in coronary artery disease.	ALOX5 ALOX15	9.91e-06	2	110	2	21558275
Pubmed	Positive and negative selection on mammalian Y chromosomes.	KDM6A UTY	9.91e-06	2	110	2	15758204
Pubmed	Lysine demethylases KDM6A and UTY: The X and Y of histone demethylation.	KDM6A UTY	9.91e-06	2	110	2	31097364
Pubmed	LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs.	LARP1 MTOR	9.91e-06	2	110	2	28650797
Pubmed	Role of endoplasmic reticulum stress in 12/15-lipoxygenase-induced retinal microvascular dysfunction in a mouse model of diabetic retinopathy.	CYBB ALOX15	9.91e-06	2	110	2	29468369
Pubmed	Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids.	ALOX5 ALOX15	9.91e-06	2	110	2	19497113
Pubmed	Interleukin-4-mediated 15-lipoxygenase-1 trans-activation requires UTX recruitment and H3K27me3 demethylation at the promoter in A549 cells.	KDM6A ALOX15	9.91e-06	2	110	2	24465480
Pubmed	Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine.	TNFSF10 DFFB	9.91e-06	2	110	2	28981092
Pubmed	Immunocytochemical localization of NTPDases1 and 2 in the neural retina of mouse and zebrafish.	ENTPD1 ENTPD2	9.91e-06	2	110	2	19116950
Pubmed	Novel associations of SNPs MYLIP rs3757354 and ABCA1 2230806 gene with early-onset-preeclampsia: A case-control candidate genetic study.	ABCA1 MYLIP	9.91e-06	2	110	2	33450693
Pubmed	Metabotropic glutamate receptor 5 knockout promotes motor and biochemical alterations in a mouse model of Huntington's disease.	GRM5 HTT	9.91e-06	2	110	2	24282028
Pubmed	Modulation of mTOR and CREB pathways following mGluR5 blockade contribute to improved Huntington's pathology in zQ175 mice.	GRM5 HTT	9.91e-06	2	110	2	30961637
Pubmed	Phosphorylation and activation of phospholipase D1 by protein kinase C in vivo: determination of multiple phosphorylation sites.	PRKCA PLD1	9.91e-06	2	110	2	10441128
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	ERAP1 H6PD PLD3 ENTPD2 ADAM17 PLOD2	1.43e-05	164	110	6	32409323
Pubmed	Early Correction of N-Methyl-D-Aspartate Receptor Function Improves Autistic-like Social Behaviors in Adult Shank2-/- Mice.	GRM5 MTOR PRKCA	1.67e-05	16	110	3	30466882
Pubmed	Human 5-, 12- and 15-lipoxygenase-1 coexist in kidney but show opposite trends and their balance changes in cancer.	ALOX5 ALOX15	2.97e-05	3	110	2	22825379
Pubmed	The ezrin-like family of tyrosine kinase substrates: receptor-specific pattern of tyrosine phosphorylation and relationship to malignant transformation.	RDX MSN	2.97e-05	3	110	2	8479753
Pubmed	Characterization of lens fiber cell triton insoluble fraction reveals ERM (ezrin, radixin, moesin) proteins as major cytoskeletal-associated proteins.	RDX MSN	2.97e-05	3	110	2	18261459
Pubmed	5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy.	ALOX5 ALOX15	2.97e-05	3	110	2	18346986
Pubmed	Ezrin, radixin, and moesin are phosphorylated in response to 2-methoxyestradiol and modulate endothelial hyperpermeability.	RDX MSN	2.97e-05	3	110	2	21659656
Pubmed	Expression, localization, and binding activity of the ezrin/radixin/moesin proteins in the mouse testis.	RDX MSN	2.97e-05	3	110	2	19064715
Pubmed	Differential involvement of ezrin/radixin/moesin proteins in sphingosine 1-phosphate-induced human pulmonary endothelial cell barrier enhancement.	RDX MSN	2.97e-05	3	110	2	21864676
Pubmed	Differential expression of ezrin/radixin/moesin (ERM) and ERM-associated adhesion molecules in the blastocyst and uterus suggests their functions during implantation.	RDX MSN	2.97e-05	3	110	2	14613898
Pubmed	HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin.	ABCA1 HTT	2.97e-05	3	110	2	16192271
Pubmed	Inhibition of cell adhesion by phosphorylated Ezrin/Radixin/Moesin.	RDX MSN	2.97e-05	3	110	2	26555866
Pubmed	Click chemistry-enabled CRISPR screening reveals GSK3 as a regulator of PLD signaling.	PRKCA PLD1	2.97e-05	3	110	2	34810254
Pubmed	PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation.	CCZ1B CCZ1	2.97e-05	3	110	2	32160108
Pubmed	Human ezrin-moesin-radixin proteins modulate hepatitis C virus infection.	RDX MSN	2.97e-05	3	110	2	23703860
Pubmed	Fibroblast-like synoviocyte migration is enhanced by IL-17-mediated overexpression of L-type amino acid transporter 1 (LAT1) via the mTOR/4E-BP1 pathway.	MTOR SLC7A5	2.97e-05	3	110	2	29198077
Pubmed	Pseudomonas aeruginosa ExoS ADP-ribosyltransferase inhibits ERM phosphorylation.	RDX MSN	2.97e-05	3	110	2	16889625
Pubmed	PLD regulates myoblast differentiation through the mTOR-IGF2 pathway.	MTOR PLD1	2.97e-05	3	110	2	18198186
Pubmed	Effect of knockdown of ezrin, radixin, and moesin on P-glycoprotein function in HepG2 cells.	RDX MSN	2.97e-05	3	110	2	21837648
Pubmed	5 S,15 S-Dihydroperoxyeicosatetraenoic Acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Reticulocyte 15-Lipoxygenase-1.	ALOX5 ALOX15	2.97e-05	3	110	2	30407793
Pubmed	Ezrin and moesin function together to promote T cell activation.	RDX MSN	2.97e-05	3	110	2	19124745
Pubmed	Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations.	SETDB1 HTT	2.97e-05	3	110	2	30452683
Pubmed	Tonic mGluR5/CB1-dependent suppression of inhibition as a pathophysiological hallmark in the striatum of mice carrying a mutant form of huntingtin.	GRM5 HTT	2.97e-05	3	110	2	23230231
Pubmed	The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice.	ALOX5 ALOX15	2.97e-05	3	110	2	8944751
Pubmed	Activation of Ras requires the ERM-dependent link of actin to the plasma membrane.	RDX MSN	2.97e-05	3	110	2	22132106
Pubmed	Membrane type 4 matrix metalloproteinase (MMP17) has tumor necrosis factor-alpha convertase activity but does not activate pro-MMP2.	ADAM17 MMP17	2.97e-05	3	110	2	10799478
Pubmed	Cell surface colony-stimulating factor 1 can be cleaved by TNF-alpha converting enzyme or endocytosed in a clathrin-dependent manner.	CYBB ADAM17	2.97e-05	3	110	2	17982061
Pubmed	The UTX gene escapes X inactivation in mice and humans.	KDM6A UTY	2.97e-05	3	110	2	9499428
Pubmed	Phospholipase D confers rapamycin resistance in human breast cancer cells.	MTOR PLD1	2.97e-05	3	110	2	12813467
Pubmed	Ezrin-radixin-moesin family proteins are involved in parvovirus replication and spreading.	RDX MSN	2.97e-05	3	110	2	19321616
Pubmed	Deciphering brain-specific transcriptomic expression of Ezr, Rad and Msn genes in the development of Mus musculus.	RDX MSN	2.97e-05	3	110	2	29906485
Pubmed	Hsa_circRNA_002144 promotes growth and metastasis of colorectal cancer through regulating miR-615-5p/LARP1/mTOR pathway.	LARP1 MTOR	2.97e-05	3	110	2	33347535
Pubmed	Distribution of ecto-nucleotidases in mouse sensory circuits suggests roles for nucleoside triphosphate diphosphohydrolase-3 in nociception and mechanoreception.	ENTPD1 ENTPD2	2.97e-05	3	110	2	21807070
Pubmed	Activation of PKC induces leukocyte adhesion by the dephosphorylation of ERM.	RDX MSN	2.97e-05	3	110	2	31843195
Pubmed	Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase.	ALOX5 ALOX15	2.97e-05	3	110	2	15328042
Pubmed	Increased phosphorylation of ezrin/radixin/moesin proteins contributes to proliferation of rheumatoid fibroblast-like synoviocytes.	RDX MSN	2.97e-05	3	110	2	21278069
Pubmed	TSC2 regulates tumor susceptibility to TRAIL-mediated T-cell killing by orchestrating mTOR signaling.	TNFSF10 MTOR	2.97e-05	3	110	2	36715448
Pubmed	Tumor cell-mediated induction of the stromal factor stromelysin-3 requires heterotypic cell contact-dependent activation of specific protein kinase C isoforms.	PRKCA MMP11	2.97e-05	3	110	2	15509588
Pubmed	FBW7/GSK3β mediated degradation of IGF2BP2 inhibits IGF2BP2-SLC7A5 positive feedback loop and radioresistance in lung cancer.	IGF2BP2 SLC7A5	2.97e-05	3	110	2	38281999
Interaction	MMP16 interactions	MMP24 MMP8 MMP11 MMP17	2.25e-06	18	108	4	int:MMP16
Interaction	MMP24 interactions	MMP24 MMP8 MMP11 MMP17	2.84e-06	19	108	4	int:MMP24
Interaction	COLQ interactions	COL4A2 FN1 TEP1 PLOD2	2.83e-05	33	108	4	int:COLQ
Interaction	FNDC5 interactions	ACACA FN1 ERAP1 CALR CALU ZG16B TMEM214 H6PD PLD3 PLBD2 PPL NRP2 MSN IGF2BP2 EBP NID1 ENDOU ADAM17 MMP11 PLOD2 POFUT2	3.03e-05	1470	108	21	int:FNDC5
Interaction	MMP11 interactions	MMP24 MMP8 MMP11	3.18e-05	12	108	3	int:MMP11
Interaction	SKIL interactions	COL4A2 FN1 PPL PIAS4 SETDB1 NID1	4.38e-05	119	108	6	int:SKIL
Cytoband	3q26	TNFSF10 PLD1	1.19e-04	7	110	2	3q26
GeneFamily	Endogenous ligands\|Matrix metallopeptidases	MMP24 MMP8 MMP11 MMP17	3.03e-06	24	77	4	891
GeneFamily	Arachidonate lipoxygenases	ALOX5 ALOX15	2.66e-04	6	77	2	407
GeneFamily	Transmembrane channel likes	TMC2 TMC3	4.93e-04	8	77	2	1135
GeneFamily	Phospholipases	PLCD4 PLD3 PLD1	7.57e-04	42	77	3	467
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	RDX MSN MYLIP	1.26e-03	50	77	3	1293
Coexpression	LIU_VAV3_PROSTATE_CARCINOGENESIS_UP	CYBB FN1 TNFSF10 NID1 GPNMB PLOD2	2.08e-06	89	110	6	M215
Coexpression	NABA_MATRISOME	COL4A2 FN1 TNFSF10 ADAMTS12 MMP24 CLEC4F LGI2 FCN2 ANGPTL3 NID1 ADAM17 MMP8 MMP11 MMP17 PLOD2 MUC4	4.78e-06	1008	110	16	MM17056
Coexpression	NABA_MATRISOME	COL4A2 FN1 TNFSF10 ADAMTS12 MMP24 CLEC4F LGI2 FCN2 ANGPTL3 NID1 ADAM17 MMP8 MMP11 MMP17 PLOD2 MUC4	5.98e-06	1026	110	16	M5889
Coexpression	BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP	FN1 TNFSF10 ERAP1 CALU LRP1B ATP8A1 MYLIP TENM1 SLC7A5 GPNMB	1.30e-05	427	110	10	M17923
Coexpression	SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP	COL4A2 FN1 MSN PTPRM ENTPD1 NID1 GPNMB MMP11 ALOX5	1.81e-05	352	110	9	M17471
Coexpression	NUYTTEN_NIPP1_TARGETS_UP	COL4A2 TNFSF10 ERAP1 PGM2L1 PLCD4 H6PD DFFB PTPRM RCBTB1 PLD1 GPNMB PLOD2 TENT2	2.06e-05	768	110	13	M6444
Coexpression	GRUETZMANN_PANCREATIC_CANCER_UP	FN1 MSN PTPN9 FLAD1 ENTPD1 NID1 MMP11 PLOD2 ALOX5	2.11e-05	359	110	9	M15193
Coexpression	GSE3920_UNTREATED_VS_IFNA_TREATED_FIBROBLAST_DN	ACACA ERAP1 PLCD4 PLD3 PLBD2 IGF2BP2 PLD1	2.22e-05	200	110	7	M6687
Coexpression	ONKEN_UVEAL_MELANOMA_UP	CALR LARP1 RDX SPATA20 TMEM214 MSN ZNF7 SETDB1 PTPRM RCBTB1 TRAPPC10 PRKCA ADAM17	2.76e-05	790	110	13	M12490
Coexpression	HEVNER_TELENCEPHALON_VASCULAR_ENDOTHELIUM_AND_MENINGEAL_CELLS	COL4A2 MYLIP NID1	3.15e-05	15	110	3	MM402
Coexpression	MARCHINI_TRABECTEDIN_RESISTANCE_DN	COL4A2 CALR NID1 SLC7A5	4.18e-05	46	110	4	M8349
Coexpression	CAIRO_LIVER_DEVELOPMENT_DN	CYBB FN1 FRYL H6PD EBP ANGPTL3 NID1	4.71e-05	225	110	7	M6175
Coexpression	PARK_APL_PATHOGENESIS_DN	CYBB COL4A2 PRKCA GPNMB	4.96e-05	48	110	4	M2541
Coexpression	CHEN_METABOLIC_SYNDROM_NETWORK	CYBB CALR PLD3 TEP1 PPL NRP2 NLRP6 ADPRH LGI2 FLAD1 ENTPD1 ENTPD2 EBP PRMT2 NID1 GPNMB	6.14e-05	1242	110	16	M1920
Coexpression	HOSHIDA_LIVER_CANCER_SUBCLASS_S1	CYBB COL4A2 PLD3 MSN SLC7A5 GPNMB CDC20	6.19e-05	235	110	7	M5311
Coexpression	NABA_MATRISOME_ASSOCIATED	TNFSF10 ADAMTS12 MMP24 CLEC4F FCN2 ANGPTL3 ADAM17 MMP8 MMP11 MMP17 PLOD2 MUC4	6.42e-05	738	110	12	MM17058
Coexpression	GSE6259_FLT3L_INDUCED_VS_WT_SPLENIC_DC_33D1_POS_DN	TMC2 CCZ1 ENTPD1 MYLIP PRKCA UTY	6.63e-05	163	110	6	M6722
Coexpression	GSE6269_HEALTHY_VS_FLU_INF_PBMC_DN	ACACA CALR CALU LARP1 PLD3 MSN	6.63e-05	163	110	6	M5640
Coexpression	NABA_ECM_REGULATORS	ADAMTS12 MMP24 ADAM17 MMP8 MMP11 MMP17 PLOD2	6.70e-05	238	110	7	M3468
Coexpression	CAIRO_LIVER_DEVELOPMENT_DN	CYBB FN1 FRYL H6PD EBP ANGPTL3 NID1	6.88e-05	239	110	7	MM1274
Coexpression	YAMAZAKI_TCEB3_TARGETS_UP	COL4A2 CALU PTPN9 PTPRM NID1 PLOD2	7.33e-05	166	110	6	M1542
Coexpression	NABA_ECM_REGULATORS	ADAMTS12 MMP24 ADAM17 MMP8 MMP11 MMP17 PLOD2	7.44e-05	242	110	7	MM17062
Coexpression	NABA_MATRISOME_ASSOCIATED	TNFSF10 ADAMTS12 MMP24 CLEC4F FCN2 ANGPTL3 ADAM17 MMP8 MMP11 MMP17 PLOD2 MUC4	7.58e-05	751	110	12	M5885
Coexpression	ZHANG_UTERUS_C0_SECRETORY_STROMAL3_NPPC_HIGH_CELL	COL4A2 FN1 CALU RDX ADPRH ATP8A1 PLOD2 POFUT2	9.03e-05	337	110	8	MM16606
Coexpression	PILON_KLF1_TARGETS_UP	ABCA1 FN1 FRYL NRP2 SETDB1 FCN2 EBP MIB1 ANGPTL3 TENT2	9.56e-05	541	110	10	MM1061
Coexpression	GAVIN_PDE3B_TARGETS	CYBB TNFSF10 ENTPD1	1.04e-04	22	110	3	M1737
Coexpression	VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP	FN1 ADAMTS12 GPNMB MMP11 PLOD2 ALOX5	1.08e-04	178	110	6	M17079
Coexpression	DELYS_THYROID_CANCER_UP	FN1 PLD3 PPL NRP2 IGF2BP2 ENTPD1 SLC7A5 MMP11 ALOX5	1.11e-04	445	110	9	M3645
Coexpression	YAMAZAKI_TCEB3_TARGETS_UP	COL4A2 CALU PTPN9 PTPRM NID1 PLOD2	1.11e-04	179	110	6	MM660
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HSERT	RAB9B PGM2L1 GRM5 LRP1B TENM2 MMP24 PTPRM KCNIP4 CACNA1G	1.20e-04	450	110	9	M39072
Coexpression	CHEN_METABOLIC_SYNDROM_NETWORK	CYBB CALR PLD3 TEP1 PPL NRP2 NLRP6 ADPRH LGI2 FLAD1 ENTPD1 ENTPD2 EBP PRMT2 NID1 GPNMB	1.21e-04	1316	110	16	MM1052
Coexpression	MURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL	COL4A2 ABCA1 FN1 CALU TMEM214 NRP2 MSN NID1 GPNMB MMP11 PLOD2	1.39e-04	681	110	11	M39175
Coexpression	GAVIN_PDE3B_TARGETS	CYBB TNFSF10 ENTPD1	1.55e-04	25	110	3	MM726
Coexpression	BYSTRYKH_HEMATOPOIESIS_STEM_CELL_SCP2_QTL_TRANS	COL4A2 TEP1 PCSK4	1.95e-04	27	110	3	M1998
Coexpression	GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN	TNFSF10 FRYL MTOR ENTPD1 PRKCA ENDOU	1.98e-04	199	110	6	M7522
Coexpression	GSE19401_UNSTIM_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN	FN1 PLD3 ATP8A1 NID1 GPNMB KDM6A	1.98e-04	199	110	6	M7659
Coexpression	GSE360_L_MAJOR_VS_M_TUBERCULOSIS_DC_UP	H6PD GRM5 ARFRP1 EBP GPNMB ALOX15	1.98e-04	199	110	6	M5213
Coexpression	GSE12198_CTRL_VS_LOW_IL2_STIM_NK_CELL_DN	ERAP1 ADPRH DFFB PLOD2 POFUT2 HTT	2.03e-04	200	110	6	M7074
Coexpression	GSE2826_WT_VS_XID_BCELL_UP	ADPRH DFFB RCBTB1 NID1 ENDOU CDC20	2.03e-04	200	110	6	M4895
Coexpression	GSE26488_WT_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_UP	CYBB MMP24 DFFB PTPN9 PRKCA SLC7A5	2.03e-04	200	110	6	M8200
Coexpression	GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDC_DN	TNFSF10 IFT172 ATP8A1 KDM6A STAG2 TENT2	2.03e-04	200	110	6	M3971
Coexpression	GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_MAC_UP	CALR PLD3 RYR2 PRKCA SLC7A5 MUC4	2.03e-04	200	110	6	M5168
Coexpression	GSE45365_NK_CELL_VS_CD8A_DC_UP	COL4A2 SLC6A19 MSN ZNF7 PTPN9 ENDOU	2.03e-04	200	110	6	M10028
Coexpression	GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDC_DN	ACACA FN1 CALU ZNF7 MMP8 POFUT2	2.03e-04	200	110	6	M4062
Coexpression	GSE17721_0.5H_VS_4H_CPG_BMDC_DN	ABCA1 TNFSF10 NRP2 IGF2BP2 ADAM17 TENT2	2.03e-04	200	110	6	M4125
Coexpression	MANNE_COVID19_ICU_VS_HEALTHY_DONOR_PLATELETS_UP	KREMEN1 ACACA SPATA20 PLBD2 MMP17	2.09e-04	128	110	5	M38978
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	RAB9B PGM2L1 GRM5 LRP1B TENM2 RYR2 NRP2 MMP24 ATP8A1 LGI2 TENM1 PRKCA KCNIP4 CACNA1G	2.20e-04	1106	110	14	M39071
Coexpression	WONG_ADULT_TISSUE_STEM_MODULE	COL4A2 ABCA1 FN1 PPP1R13B TENM2 RYR2 MSN ENTPD1 NID1 MMP17 MUC4	2.28e-04	721	110	11	M1999
Coexpression	BYSTRYKH_HEMATOPOIESIS_STEM_CELL_SCP2_QTL_TRANS	COL4A2 TEP1 PCSK4	2.69e-04	30	110	3	MM853
Coexpression	PILON_KLF1_TARGETS_UP	ABCA1 FN1 FRYL NRP2 SETDB1 EBP MIB1 ANGPTL3 TENT2	2.75e-04	503	110	9	M2226
Coexpression	HEVNER_CORTEX_CAUDAL_CORTICAL_PLATE	TENM2 CACNA1G CACNA2D3	2.97e-04	31	110	3	MM439
Coexpression	HOLLERN_EMT_BREAST_TUMOR_UP	FN1 CALU NRP2 ADPRH POFUT2	3.16e-04	140	110	5	M617
Coexpression	ROZANOV_MMP14_TARGETS_SUBSET	COL4A2 FN1 PLOD2	3.58e-04	33	110	3	M9167
Coexpression	ZHONG_PFC_C1_DLX5_POS_INTERNEURON	RDX PRKCA	3.62e-04	7	110	2	M39091
Coexpression	HOLLERN_EMT_BREAST_TUMOR_UP	FN1 CALU NRP2 ADPRH POFUT2	3.83e-04	146	110	5	MM964
Coexpression	ATM_DN.V1_UP	ACACA H6PD LCT PPL SLC7A5	3.83e-04	146	110	5	M2692
Coexpression	P53_DN.V2_UP	CYP2A13 H6PD ANGPTL3 ATP12A MMP17	4.08e-04	148	110	5	M2694
Coexpression	LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP	CALU MSN IGF2BP2 PLOD2	4.18e-04	83	110	4	M15975
CoexpressionAtlas	kidney_adult_RenMedVasc_Tie2_k-means-cluster#3_top-relative-expression-ranked_500	ABCA1 TNFSF10 NRP2 ATP8A1 PTPRM MMP11	3.44e-05	120	108	6	gudmap_kidney_adult_RenMedVasc_Tie2_k3_500
CoexpressionAtlas	dev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_1000	ABCA1 ACACA ERAP1 CALR LARP1 PLD3 PLBD2 GREB1L IGF2BP2 ATP8A1 SLC7A5 MMP11 PLOD2 POFUT2 UTY	4.10e-05	884	108	15	gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#2_top-relative-expression-ranked_1000	LCT TENM2 RYR2 NRP2 ENTPD1 EBP PRKCA ENDOU MMP17	5.66e-05	337	108	9	gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_1000_k2
CoexpressionAtlas	Myeloid Cells, MF.Thio5.II-480hi.PC, CD115+ MHC II- F480hi Siglec F-, Peritoneal Cavity, avg-3	CYBB ABCA1 FN1 PLD3 PTPRM ENTPD1 PLD1 GPNMB ALOX5 ALOX15	8.52e-05	441	108	10	GSM605862_500
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CYBB FN1 CALR CALU PLBD2 MALRD1 GPNMB	4.90e-07	191	110	7	51535232e889db52a9b24e5696b1687e93dd7302
ToppCell	tumor_Lung-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	FN1 CALU NRP2 ADAMTS12 MMP11 PLOD2 CACNA2D3	6.45e-07	199	110	7	f89d67e3d8cd48ef5c30a5ad71764f4ebbc8bcb3
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL4A2 FN1 TNFSF10 RDX MSN IGF2BP2 PTPRM	6.67e-07	200	110	7	2d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYBB GPNMB MMP8 MMP17 ALOX5 HTT	2.80e-06	159	110	6	0c2437da5443fc3aff66f8ef311f02aa434a1fb0
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage\|343B / Donor, Lineage, Cell class and subclass (all cells)	CYBB FN1 TEP1 ADAM17 GPNMB MMP17	3.35e-06	164	110	6	057ca87847373eff7fe97dd9f4358509e66ca4c3
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|343B / Donor, Lineage, Cell class and subclass (all cells)	CYBB SLC2A9 FN1 ADAM17 GPNMB MMP17	4.87e-06	175	110	6	d3890bd0c570bb81434fdd1c5229891cefe2e462
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYBB ABCA1 FN1 PLD3 GPNMB ALOX5	6.29e-06	183	110	6	103c4c4595d8daa677679fd2fa1e99cd398e56dd
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PGM2L1 LRP1B NRP2 IGF2BP2 KCNIP4 CACNA2D3	7.57e-06	189	110	6	8c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PGM2L1 LRP1B NRP2 IGF2BP2 KCNIP4 CACNA2D3	7.57e-06	189	110	6	5d902a4660a27548764bf04c6de152b565da835c
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_2\|343B / Donor, Lineage, Cell class and subclass (all cells)	CYBB SLC2A9 FN1 ADAM17 GPNMB ALOX5	7.80e-06	190	110	6	6514f00d222eef08c282face7f177259bca62f0e
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 FN1 CALU LGI2 ENTPD2 NID1	8.28e-06	192	110	6	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	Entopeduncular-Neuronal\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	RAB9B PGM2L1 TENM2 MMP24 TENM1 KCNIP4	8.28e-06	192	110	6	4c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	SDK2 FN1 RYR2 NRP2 ADAMTS12 PTPRM	8.28e-06	192	110	6	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FN1 TENM2 NRP2 ADAMTS12 ENTPD2 NID1	8.53e-06	193	110	6	549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 CALU H6PD ENTPD2 NID1 GPNMB	8.53e-06	193	110	6	49600db68ed65cafc67bd45a285b364e4f5f88af
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	SDK2 FN1 RYR2 NRP2 ADAMTS12 CACNA2D3	8.53e-06	193	110	6	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	SDK2 FN1 TENM2 RYR2 ADAMTS12 NID1	8.53e-06	193	110	6	acad568621ed677031797b8c2e34dafea798d681
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 FN1 CALU ENTPD2 NID1 GPNMB	8.53e-06	193	110	6	45b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCell	metastatic_Brain-Myeloid_cells-Microglia/Mac\|Myeloid_cells / Location, Cell class and cell subclass	IFT172 ZG16B PLD3 NRP2 LGI2 GPNMB	9.04e-06	195	110	6	98a21f5e27d98384b3086034bd6f83441e2e4ef9
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FN1 CALU PGM2L1 NRP2 MMP11 PLOD2	9.86e-06	198	110	6	c55608633f66e3d434c5d81324efb07c5120d2c2
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CYBB ABCA1 FN1 NRP2 GPNMB ALOX5	9.86e-06	198	110	6	579a22199643440b98e381147779ced630d4ed66
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL4A2 FN1 CALU ADAMTS12 NID1 MMP11	9.86e-06	198	110	6	8b9e8eaeffda40912a0163fdf39b93bc5e64751c
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FN1 CALU PGM2L1 NRP2 MMP11 PLOD2	9.86e-06	198	110	6	3e5459038fc6ed95f529eb4d1dc5113e16c19012
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL4A2 FN1 CALU ADAMTS12 NID1 MMP11	9.86e-06	198	110	6	eb78b2ae6a787dbc75947e8dd5a03693285bc8be
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA1 SLC2A9 PLBD2 ENTPD1 GPNMB ALOX5	9.86e-06	198	110	6	0b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCell	NS-moderate-d_07-13-Epithelial-Secretory-diff\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CYP2A13 TNFSF10 ZG16B ATP12A MUC4 ALOX15	9.86e-06	198	110	6	361f3062f73a0add16dd6fbe927698416515879f
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TNFSF10 ZG16B ENTPD2 ATP12A MUC4 ALOX15	1.01e-05	199	110	6	73704e8d774b3d08a311f69137972b07015c38f6
ToppCell	proximal-Epithelial-Differentiating_Basal-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP2A13 TNFSF10 ZG16B ATP12A MUC4 ALOX15	1.01e-05	199	110	6	c607346f60e5997e757e5a31cab412ab3734377b
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ABCA1 SDK2 FN1 RYR2 ADAMTS12 NID1	1.01e-05	199	110	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A2 TENM2 NRP2 ADAMTS12 NID1 CACNA2D3	1.01e-05	199	110	6	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	3'_v3-Lung-Myeloid_Mac\|Lung / Manually curated celltypes from each tissue	CYBB FN1 PLD3 ADAM17 GPNMB ALOX5	1.01e-05	199	110	6	1677aaee5b7f5f262e27df5d9f1bdf6e21e3d804
ToppCell	IPF-Myeloid-Macrophage\|Myeloid / Disease state, Lineage and Cell class	COL4A2 ABCA1 CALU PLBD2 NRP2 GPNMB	1.01e-05	199	110	6	3c2b362d5e824e1a04830e70352f8818de984174
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A2 TENM2 NRP2 ADAMTS12 NID1 CACNA2D3	1.01e-05	199	110	6	9c2db0bb94cba71a3cc1827844da090e213e0258
ToppCell	(02)_MMP9/10+\|World / shred by cell type by condition	COL4A2 SDK2 FN1 TENM2 MSN SLC7A5	1.01e-05	199	110	6	3f78eddeaa67d3b767aa38de765632166b09a4f0
ToppCell	proximal-3-Epithelial-Differentiating_Basal\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP2A13 TNFSF10 ZG16B ATP12A MUC4 ALOX15	1.01e-05	199	110	6	12e07084fc2d5d4c418df564ccc0e132b056e549
ToppCell	proximal-Epithelial-Differentiating_Basal\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP2A13 TNFSF10 ZG16B ATP12A MUC4 ALOX15	1.01e-05	199	110	6	96a89a2578fad9a99c52d2cf9e26e06516a96568
ToppCell	3'_v3-Lung-Myeloid_Mac-Alveolar_macrophages\|Lung / Manually curated celltypes from each tissue	CYBB FN1 PLD3 ADAM17 GPNMB ALOX5	1.01e-05	199	110	6	eec1b086e5e8b9b0e1770dd269ca903f713d99a8
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CYBB ABCA1 PLD3 PLBD2 NRP2 GPNMB	1.01e-05	199	110	6	54a54ad983503ed515d476882d86b17d97892037
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CYBB FN1 PLD3 NRP2 GPNMB ALOX5	1.04e-05	200	110	6	bc56d6d6d32405685e9bd553ebdbe48b8fbe6902
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CYBB FN1 CALR CALU PLD3 GPNMB	1.04e-05	200	110	6	d0ffd0d403a335c477c1b72391078b1595d9630c
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	COL4A2 TNFSF10 PPP1R13B RDX IGF2BP2 PTPRM	1.04e-05	200	110	6	6f531a418ff25b59a543800cf4bce7b72404ce08
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	ABCA1 FN1 CALR PLD3 NRP2 GPNMB	1.04e-05	200	110	6	195862a319794e57f0506757ae45ab70200bc5b4
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial\|10w / Sample Type, Dataset, Time_group, and Cell type.	COL4A2 FN1 MSN ENTPD2 NID1 MMP11	1.04e-05	200	110	6	ff0b2675c68e9fc1fa16b3276431f199f3642eac
ToppCell	Severe_COVID-19-Myeloid-MoAM4\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	CYBB ABCA1 CALU PLD3 NRP2 GPNMB	1.04e-05	200	110	6	30448a41ca64d6f0fedaff0b7a6670dd33cdf2c5
ToppCell	BAL-Severe-Myeloid-MoAM-MoAM4-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYBB ABCA1 CALU PLD3 NRP2 GPNMB	1.04e-05	200	110	6	4f481d87e30195365900acb5d50641a9e7b2f462
ToppCell	Control_saline-Endothelial-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	COL4A2 TNFSF10 RDX IGF2BP2 PTPRM ENTPD1	1.04e-05	200	110	6	e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCell	BAL-Severe-Myeloid-MoAM-MoAM4-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CYBB ABCA1 CALU PLD3 NRP2 GPNMB	1.04e-05	200	110	6	5490393c5f54748f912676e19b58bd1320415a06
ToppCell	metastatic_Lymph_Node-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	ABCA1 FN1 CALR PLD3 NRP2 GPNMB	1.04e-05	200	110	6	4758b96725699641b55a665533adf2d238032b09
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial-Proteoglycan-expressing_cell\|10w / Sample Type, Dataset, Time_group, and Cell type.	COL4A2 FN1 MSN ENTPD2 NID1 MMP11	1.04e-05	200	110	6	07d2133c85e0a4eb8bef653ee15ecd0f1b2bbd44
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_macrophage\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CYBB FN1 PLD3 NRP2 GPNMB ALOX5	1.04e-05	200	110	6	d08c0b10cd95bfb462792e368627b3e36582b263
ToppCell	Severe-Myeloid-Macrophages-FCN1-SPP1+\|Severe / Condition, Lineage, Cell class and cell subclass	ABCA1 CALU PLD3 PLBD2 NRP2 GPNMB	1.04e-05	200	110	6	b8cd209b810312793465b28bb2a6cbe5d94da91f
ToppCell	COVID-19-Myeloid-MoAM2,_CCL18\|Myeloid / Condition, Lineage and Cell class	ABCA1 CALR CALU PLD3 NRP2 GPNMB	1.04e-05	200	110	6	a60346c5ea7a3dae1ad3c5dc6c6eca65b64c6888
ToppCell	Control_saline-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	COL4A2 TNFSF10 RDX IGF2BP2 PTPRM ENTPD1	1.04e-05	200	110	6	3372c488a39fe812fa94e4f0564594186fea3db5
ToppCell	BAL-Severe-Myeloid-MoAM-MoAM4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYBB ABCA1 CALU PLD3 NRP2 GPNMB	1.04e-05	200	110	6	cf720d3973e79ffd4c6e763a7284799ced22a274
ToppCell	BAL-Severe-Myeloid-MoAM-MoAM4\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYBB ABCA1 CALU PLD3 NRP2 GPNMB	1.04e-05	200	110	6	df821ac12953e44fcfedbbefb35a4976e406ccd6
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RYR2 ENTPD1 TENM1 NID1 CACNA1G CACNA2D3	1.04e-05	200	110	6	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMC2 LRP1B USP26 TENM1 ATP12A	3.03e-05	145	110	5	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SDK2 FRYL MYLIP PRKCA PCSK4	3.56e-05	150	110	5	744050a1b665c6989f37141348af3df7579a73c9
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB COL4A2 FN1 MMP8 MUC4	3.91e-05	153	110	5	0ef7c45cdd854c79e527006034029767f8e108b2
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	SDK2 MYLIP PRKCA SLC7A5 PCSK4	4.03e-05	154	110	5	874b1220337276489a89fcc9a39bc81ba6b68baf
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA1 PLD3 PLBD2 GPNMB MMP8	4.70e-05	159	110	5	4b840da854390f8285c219314cff4434d7ffcacc
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA1 PLD3 PLBD2 GPNMB MMP8	4.70e-05	159	110	5	d9e535cf9a0a2302268f2897b010dcecc6426e41
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA1 PLD3 PLBD2 GPNMB MMP8	4.70e-05	159	110	5	29999c87f5823f734e5cbf8ea8b729ec017db9b3
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRABD2A FRYL ATP8A1 TENM1 PRMT2	4.98e-05	161	110	5	5fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMC2 LRP1B USP26 TENM1 ATP12A	5.13e-05	162	110	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAM178B LRP1B ATP8A1 CCZ1 MUC4	5.13e-05	162	110	5	8e0f03fcc25b2ea777e8478fbf771699cf93719c
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYBB PLD3 GPNMB ALOX5 ALOX15	5.13e-05	162	110	5	d712bc31840ad1523e3dbf884acbb428a8995001
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAM178B LRP1B ATP8A1 CCZ1 MUC4	5.13e-05	162	110	5	e0417f1242edf71934fe62bccc55c4678f7ff4ac
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Myeloid-macrophage\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB TNFSF10 MMP8 ALOX5 CACNA2D3	5.29e-05	163	110	5	57f02f2b9ce940a2962bb57cd8d02eb67b6f44a3
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Myeloid\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB TNFSF10 MMP8 ALOX5 CACNA2D3	5.29e-05	163	110	5	155ac52a34e0d55545aab8a3e4162fc4c387e697
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Myeloid-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB TNFSF10 MMP8 ALOX5 CACNA2D3	5.29e-05	163	110	5	c132fb5b56186a10d33ae5ce17b2a7e670d52f79
ToppCell	Club_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	CYP2A13 TNFSF10 ZG16B ATP12A MUC4	5.93e-05	167	110	5	dbdaaeb3bd9139cb008d9fe24ec031fc5628f136
ToppCell	3'_v3-bone_marrow-Myeloid_Mac-Intermediate_macrophages\|bone_marrow / Manually curated celltypes from each tissue	ABCA1 FN1 NRP2 GPNMB MMP8	6.10e-05	168	110	5	8ade4d098aeecda2d80c1cad1cebe9a063eae948
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	FAM178B PRMT2 CACNA1G PLOD2 UTY	6.10e-05	168	110	5	b94b1f37c92e019d01ecfa3b7cc6797b6e4a56ff
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	COL4A2 L3MBTL2 IGF2BP2 RCBTB1 NID1	6.27e-05	169	110	5	ea600c63cf9572bc4b3cad6392f67bd0d92c7fc9
ToppCell	droplet-Liver-nan-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRM ENTPD1 MIB1 MMP8 MMP17	6.82e-05	172	110	5	f814b6134ad608015765399d54cc1e5e1873ed34
ToppCell	TCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-5\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	CYP2A13 ZG16B GRM5 ATP12A ALOX15	6.82e-05	172	110	5	6b8a8d3b97c10b9d092307eed3cacbd2745df185
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CYP2A13 ZG16B IGF2BP2 ATP12A MUC4	7.01e-05	173	110	5	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDK2 FRYL MTOR PRKCA MUC4	7.20e-05	174	110	5	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A2 ADAMTS12 LGI2 PTPRM MMP8	7.40e-05	175	110	5	955f10982a487e12cdc3a9f80b3be06bf6c59de7
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FN1 PLD3 ADAM17 GPNMB ALOX5	8.02e-05	178	110	5	0b398656f26c4061b11ccf98908d0e2e1367585a
ToppCell	droplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYBB ABCA1 PLD3 NRP2 CLEC4F	8.02e-05	178	110	5	c85de851b39cb8ef7ea1866ab64c6a387788273a
ToppCell	3'_v3-bone_marrow-Myeloid_Mac-Macrophage\|bone_marrow / Manually curated celltypes from each tissue	ABCA1 FN1 NRP2 CACNA1G GPNMB	8.02e-05	178	110	5	11a338032b59b936c5e65517c4160f7dd47a2cda
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A2 LGI2 PTPRM TENM1 PLOD2	8.23e-05	179	110	5	d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	KREMEN1 RYR2 ATP8A1 ENTPD1 CACNA2D3	8.23e-05	179	110	5	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A2 SDK2 KREMEN1 ADAMTS12 NID1	8.23e-05	179	110	5	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A2 ABCA1 FN1 NID1 MMP17	8.45e-05	180	110	5	f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1B MALRD1 SLC7A5 KCNIP4 CACNA2D3	8.45e-05	180	110	5	eee71184ebed2694d3e60f579a44b3cf7dd2cd35
ToppCell	Control-Epithelial-Goblet\|Control / Disease state, Lineage and Cell class	CYP2A13 ZG16B PPL ATP12A MUC4	8.45e-05	180	110	5	5293d23b8b8ea587239ffde561b70bad01632521
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRP1B MALRD1 SLC7A5 KCNIP4 CACNA2D3	8.45e-05	180	110	5	a17dbe03597b81e7a1fe2bf2d23e59e55c615a2a
ToppCell	Control-Myeloid-Alveolar_macrophages\|Control / group, cell type (main and fine annotations)	CYBB SLC2A9 FN1 GPNMB ALOX5	8.67e-05	181	110	5	8d2102c8c86c59a82610f26f90946b290552e666
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 FN1 ADAMTS12 NID1 MMP17	8.67e-05	181	110	5	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RAB9B SDK2 FN1 FAM178B RYR2	8.67e-05	181	110	5	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 FN1 ADAMTS12 NID1 MMP17	8.67e-05	181	110	5	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYBB CACNA1G ADAM17 GPNMB ALOX5	8.90e-05	182	110	5	4234d0cc57b5266a5e03133c75c7918abe48465e
ToppCell	3'_v3-bone_marrow-Myeloid_Mac\|bone_marrow / Manually curated celltypes from each tissue	ABCA1 FN1 NRP2 CACNA1G GPNMB	8.90e-05	182	110	5	e1d6b5de5bd1d11e968da3a55e5326ef252f55ba
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MARCHF10 LRP1B PPL KCNIP4 CACNA2D3	8.90e-05	182	110	5	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZG16B PGM2L1 NRP2 ATP12A MUC4	9.37e-05	184	110	5	01c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FN1 ADAMTS12 LGI2 MMP11 PLOD2	9.61e-05	185	110	5	87c416d14ca6255bee39b16e7571553e36ee3069
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYBB ABCA1 PLD3 GPNMB ALOX5	9.61e-05	185	110	5	4bee178ede12f56ba5f5bec44a03dc2a62c50137
Drug	hydroxyl radicals	CYP2A13 FN1 PPP1R13B RDX PLCD4 H6PD LCT LRP1B PPL USP26 ADPRH PTPN9 ATP8A1 PTPRM FLAD1 ENTPD1 ENTPD2 PRKCA USP4 PLD1 ATP12A PLOD2 ALOX5	7.42e-08	1341	109	23	CID000000961
Drug	Pro-leu-gly	MMP24 NID1 ADAM17 MMP8 MMP17	1.39e-07	26	109	5	CID000169533
Drug	quinacrine	PLD3 LCT MMP24 PRKCA PLD1 MMP8 MMP11 MMP17 ALOX5 ALOX15	2.70e-07	243	109	10	CID000000237
Drug	enantio-PAF-C16	PLCD4 MMP24 FCN2 ENTPD1 PRKCA MMP8 MMP11 MMP17 ALOX5 ALOX15	2.80e-07	244	109	10	CID000002499
Drug	genistein	FN1 TNFSF10 CALU PLCD4 PLD3 RYR2 MMP24 PTPRM MTOR MYLIP PRKCA CACNA1G ADAM17 PLD1 MMP8 CDC20 MMP11 MMP17 ALOX5 CACNA2D3	3.08e-07	1117	109	20	CID005280961
Drug	AC1L9M3B	CALR MMP24 PRKCA MMP8 MMP11 MMP17	4.70e-07	61	109	6	CID000448562
Drug	D-myo-inositol-1,4,5-triphosphate	FN1 CALR PLCD4 PLD3 GRM5 RYR2 DFFB MTOR ENTPD1 PRKCA CACNA1G PLD1 CACNA2D3 HTT	5.62e-07	568	109	14	CID000000806
Drug	1-Butanol	ABCA1 GRM5 MTOR PRKCA PLD1 ALOX5	1.07e-06	70	109	6	ctd:D020001
Drug	U46619	FN1 PLCD4 RYR2 PTPRM ENTPD1 PRKCA CACNA1G ALOX5 ALOX15 CACNA2D3	1.16e-06	285	109	10	CID000005618
Drug	MMI270	MMP24 ADAM17 MMP8 MMP17	1.44e-06	18	109	4	CID000446504
Drug	A0395	FN1 MMP24 ADAM17 MMP8 MMP11 MMP17	1.61e-06	75	109	6	CID009906466
Drug	NSC236997	FN1 TNFSF10 H6PD RAD54L2 LCT RYR2 MMP24 MTOR PRKCA MMP8 MMP11 MMP17 ALOX15	1.87e-06	539	109	13	CID000005300
Drug	polyethylenimine	FN1 CALU RYR2 MMP24 ADAM17 MMP11 MMP17	2.79e-06	128	109	7	CID000009033
Drug	H2O2	CYBB FN1 TNFSF10 CALR CALU PLCD4 SPATA20 H6PD PLD3 RYR2 MTOR PRKCA SLC7A5 ADAM17 PLD1 CDC20 MMP11 ALOX5 ALOX15	3.18e-06	1183	109	19	CID000000784
Drug	AC1Q6A8A	CYBB ABCA1 ALOX5	3.68e-06	7	109	3	CID000160255
Drug	rishitin	CYBB ABCA1 ALOX5	3.68e-06	7	109	3	CID000108064
Drug	SKF 104353	FN1 PRKCA ALOX5 ALOX15	4.91e-06	24	109	4	CID000060842
Drug	PHA-00745360 [351320-33-7]; Up 200; 10uM; PC3; HT_HG-U133A	ABCA1 TNFSF10 RYR2 ATP8A1 ENTPD1 ATP12A MMP11 UTY	5.09e-06	198	109	8	3824_UP
Drug	NSC350593	CYBB FN1 PLCD4 PLD3 PRKCA PLD1 MMP8 ALOX5 ALOX15	5.97e-06	269	109	9	CID000004364
Drug	Isoproterenol	ABCA1 ACACA FN1 TNFSF10 CALR PGM2L1 RYR2 DFFB IGF2BP2 MTOR ENTPD1 MYLIP MIB1 PRKCA PLD1 GPNMB MMP11	6.56e-06	1016	109	17	ctd:D007545
Drug	DA-125	MMP24 MMP8 MMP11 MMP17	6.85e-06	26	109	4	CID000114758
Drug	myo-inositol	ACACA CALR PLCD4 PLD3 LCT GRM5 RYR2 MTOR PRKCA CACNA1G PLD1 MMP17 ALOX5 ALOX15 CACNA2D3	7.47e-06	811	109	15	CID000000892
Drug	AC1L1KC5	TNFSF10 CALR CALU PLD3 GRM5 RYR2 ENTPD1 PRKCA CACNA1G PLD1 ALOX5 CACNA2D3	1.11e-05	541	109	12	CID000005428
Drug	mercuric acetate	MMP24 MMP8 MMP11 MMP17	1.24e-05	30	109	4	CID000015337
Drug	DOPPA	PLD3 PRKCA PLD1	1.25e-05	10	109	3	CID003034821
Drug	D 609	CALR PLCD4 PLD3 PRKCA PLD1	1.40e-05	64	109	5	CID000002940
Drug	AC1L1JM9	FN1 TNFSF10 CALU PLD3 MTOR PRKCA SLC7A5 ADAM17 PLD1	1.59e-05	304	109	9	CID000005103
Drug	dibutyryl cyclic 3',5'-AMP	ABCA1 FN1 PLD3 MMP24 MTOR FCN2 PRKCA PLD1 MMP8 MMP11 MMP17 ALOX5	1.59e-05	561	109	12	CID000002460
Drug	magnesium	RAB9B FN1 PGM2L1 GRM5 RYR2 MMP24 ADPRH DFFB FLAD1 ENTPD1 ENTPD2 PRKCA ADAM17 PLD1 MMP8 ATP12A MMP11 MMP17 ALOX5	1.60e-05	1325	109	19	CID000000888
Drug	malolactomycin D	MMP24 MMP8 MMP11 MMP17	1.61e-05	32	109	4	CID006449115
Drug	RHC 80267	PLCD4 PLD3 PRKCA PLD1 ALOX5 ALOX15	1.66e-05	112	109	6	CID000005063
Drug	KI-8110	FN1 ORM2 CLEC4F	1.71e-05	11	109	3	CID003081597
Drug	aldosterone	FN1 RYR2 MMP24 PRKCA SLC7A5 CACNA1G MMP8 MMP11 MMP17 CACNA2D3	2.13e-05	397	109	10	CID000005839
Drug	TMB-8	PLD3 RYR2 PRKCA CACNA1G PLD1 ALOX5 ALOX15	2.25e-05	176	109	7	CID000005494
Drug	quercetin 3-O-glucopyranoside	ACACA ALOX15	2.27e-05	2	109	2	ctd:C110309
Drug	canola oil	TNFSF10 NRP2 MSN ENTPD1 PLD1 ALOX15	2.70e-05	122	109	6	ctd:C061996
Drug	pyrachlostrobin	CYBB ABCA1 SLC2A9 FN1 ERAP1 PLCD4 TEP1 MSN NID1 GPNMB CDC20 MMP11 PLOD2 ALOX5	3.30e-05	811	109	14	ctd:C513428
Drug	AC1L1KS5	PLCD4 PLD3 GRM5 RYR2 ENTPD1 PRKCA CACNA1G PLD1 CACNA2D3	3.33e-05	334	109	9	CID000005631
Drug	Ketoconazole [65277-42-1]; Up 200; 7.6uM; HL60; HT_HG-U133A	COL4A2 ACACA ERAP1 SPATA20 RYR2 ENTPD1 SLC7A5	3.55e-05	189	109	7	1285_UP
Drug	Fluvastatin sodium salt [93957-55-2]; Down 200; 9.2uM; PC3; HT_HG-U133A	TNFSF10 RYR2 NRP2 ENTPD1 PLD1 GPNMB HTT	4.05e-05	193	109	7	6691_DN
Drug	trifluoperazine dihydrochloride; Down 200; 10uM; HL60; HT_HG-U133A	CYBB SLC2A9 FN1 CALR SETDB1 FLAD1 CACNA2D3	4.19e-05	194	109	7	2684_DN
Drug	1,10-phenanthroline	ACACA FN1 MMP24 ADAM17 PLD1 MMP8 MMP11 MMP17	4.40e-05	267	109	8	CID000001318
Drug	Trimetazidine dihydrochloride [13171-25-0]; Up 200; 11.8uM; MCF7; HT_HG-U133A	FN1 RAD54L2 PTPRM TENM1 PRKCA NID1 UTY	4.47e-05	196	109	7	2876_UP
Drug	Hymecromone [90-33-5]; Up 200; 22.8uM; PC3; HT_HG-U133A	GREB1L MMP24 ENTPD1 ENTPD2 PRKCA CACNA1G MUC4	4.47e-05	196	109	7	4623_UP
Drug	Azaperone [1649-18-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A	RAD54L2 PLD3 TEP1 ARFRP1 MTOR PRMT2 KDM6A	4.62e-05	197	109	7	7231_DN
Drug	estradiol, USP; Up 200; 0.01uM; PC3; HT_HG-U133A	TNFSF10 PLD3 RYR2 NRP2 ADPRH ENTPD1 PLD1	4.77e-05	198	109	7	1241_UP
Drug	2-propylpentanoic acid; Up 200; 50uM; PC3; HT_HG-U133A	TNFSF10 PLD3 PIAS4 MMP24 ADPRH ENTPD1 PLD1	4.77e-05	198	109	7	1222_UP
Drug	Mephenesin [59-47-2]; Up 200; 22uM; MCF7; HT_HG-U133A	SLC2A9 ENTPD1 PRKCA GPNMB MMP11 MUC4 ALOX5	4.77e-05	198	109	7	2304_UP
Drug	raloxifene	PPP1R13B PLD3 MMP24 ARFRP1 EBP PLD1 MMP8 MMP11 MMP17	4.89e-05	351	109	9	CID000005035
Drug	Natamycin [7681-93-8]; Down 200; 6uM; HL60; HT_HG-U133A	SLC2A9 ERAP1 ZNF250 PIAS4 ENTPD1 PRMT2 KDM6A	4.92e-05	199	109	7	6126_DN
Drug	Arecoline hydrobromide [300-08-3]; Up 200; 17uM; MCF7; HT_HG-U133A	SLC2A9 GREB1L NID1 PLD1 GPNMB MMP8 MMP17	4.92e-05	199	109	7	5423_UP
Drug	carvedilol	FN1 RYR2 MSN PRKCA GPNMB MMP8	4.97e-05	136	109	6	ctd:C043211
Drug	HEPES	CALU MTOR FCN2 NID1 SLC7A5 MMP8	4.97e-05	136	109	6	CID000023830
Drug	Benzathine benzylpenicillin [5928-84-7]; Down 200; 4.2uM; HL60; HT_HG-U133A	COL4A2 H6PD RAD54L2 PIAS4 IGF2BP2 POFUT2 UTY	5.08e-05	200	109	7	2939_DN
Drug	Cck (26-33)	PLD3 PRKCA PLD1	5.71e-05	16	109	3	CID003081599
Drug	AC1L1O6Q	FN1 CALR PLCD4 PLD3 PRKCA PLD1	6.08e-05	141	109	6	CID000058035
Drug	fenobam	CALR GRM5	6.79e-05	3	109	2	CID000162834
Drug	AC1L1JRO	FN1 MMP8	6.79e-05	3	109	2	CID000005176
Drug	kazinol B	RYR2 PRKCA ALOX5	6.91e-05	17	109	3	CID000480869
Drug	1,2-dipalmitoy	PLD3 PPL PLD1 PCSK4	7.56e-05	47	109	4	CID000003098
Drug	peroxynitrite	CYBB FN1 RYR2 MMP24 FCN2 PRKCA MMP8 MMP11 MMP17	7.79e-05	373	109	9	CID000104806
Drug	AC1O5PL5	ALOX5 ALOX15 HTT	8.27e-05	18	109	3	CID006438380
Drug	Nicotine	CYP2A13 ACACA FN1 CALR PLCD4 GRM5 RYR2 DFFB IGF2BP2 MTOR PRKCA SLC7A5 PLD1 GPNMB ALOX5	8.39e-05	1000	109	15	ctd:D009538
Drug	mangrove	ABCA1 ACACA PLD3 LCT LRP1B PPL PRKCA PLD1 ALOX5 ALOX15	8.49e-05	468	109	10	CID000000965
Drug	MW 1	PGM2L1 LCT RYR2 PIAS4 ENDOU HTT	8.89e-05	151	109	6	CID000073965
Drug	5-ASA	PLD3 PLD1 ALOX5 ALOX15	9.66e-05	50	109	4	CID000004075
Drug	thiomalate	DFFB PRKCA SLC7A5 ALOX5	9.66e-05	50	109	4	CID000006268
Drug	AC1MW7VF	CYBB RYR2 DFFB	9.78e-05	19	109	3	CID000414699
Drug	Pz-plgpa	FN1 PPL MMP8	9.78e-05	19	109	3	CID000152296
Drug	noradrealine	ACACA PLCD4 RYR2 MMP24 PRKCA CACNA1G PLD1 MMP8 MMP11 MMP17 CACNA2D3	9.95e-05	575	109	11	CID000000951
Drug	isoflavone	LCT MMP24 MTOR MMP8 MMP11 MMP17	1.03e-04	155	109	6	CID000072304
Drug	quercetin	FN1 TNFSF10 MMP24 MTOR PRKCA MMP8 MMP11 MMP17 ALOX5 ALOX15	1.08e-04	482	109	10	CID005280343
Drug	phorbol acetate myristate	CYBB FN1 CALU PLCD4 PLD3 RYR2 PTPN9 PTPRM MTOR PRKCA CACNA1G ADAM17 PLD1 MMP8 MUC4 ALOX5 ALOX15 CACNA2D3	1.11e-04	1399	109	18	CID000004792
Drug	5-nitro-2-(3-phenylpropylamino)benzoic acid	CALU ENTPD1 ENTPD2 ALOX5	1.13e-04	52	109	4	CID000004549
Drug	POPC	ABCA1 PLCD4 PLD3 PPL PRKCA PLD1 ALOX5 ALOX15	1.14e-04	306	109	8	CID000065167
Drug	NSC107658	SLC2A9 FN1 ATE1 PLD3 PRKCA PLD1 MMP8 ALOX5	1.14e-04	306	109	8	CID000002919
Drug	Drugs, Chinese Herbal	SLC2A9 ACACA TNFSF10 PGM2L1 TEP1 MTOR PRKCA CACNA1G CDC20 KDM6A ALOX5	1.18e-04	586	109	11	ctd:D004365
Drug	lysosphingomyelin	FN1 PLCD4 PLD3 RYR2 PRKCA PLD1	1.22e-04	160	109	6	CID000005263
Drug	2-(aminomethyl)pyrrolidine	PLCD4 ENTPD1 ENTPD2 PRKCA PLD1 ALOX5	1.27e-04	161	109	6	CID000072032
Drug	Glucose	CYBB COL4A2 SLC2A9 ACACA FN1 CALR CALU ATE1 LCT SETDB1 MTOR MIB1 PRKCA PLD1 CDC20 PLOD2 STAG2 ALOX5	1.34e-04	1420	109	18	ctd:D005947
Drug	methyl orsellinate	ALOX5 ALOX15	1.35e-04	4	109	2	CID000076658
Drug	CF-NP	FN1 MSN	1.35e-04	4	109	2	CID000026247
Drug	lipoxin A5	ALOX5 ALOX15	1.35e-04	4	109	2	CID006439927
Drug	phillyrin	FN1 ALOX5	1.35e-04	4	109	2	CID000101712
Drug	acetate	ACACA RDX PGM2L1 PLBD2 MMP24 FCN2 PRKCA MMP8 MMP11 MMP17 ALOX5	1.42e-04	599	109	11	CID000000175
Drug	Losartan	CYBB COL4A2 SLC2A9 FN1 ALOX5 ALOX15	1.45e-04	165	109	6	ctd:D019808
Drug	AC1Q5THZ	CYBB PLCD4 H6PD PLD3 ENTPD1 PRKCA PLD1 MMP8 ALOX5 ALOX15	1.51e-04	502	109	10	CID000001959
Drug	BM 13.177	ENTPD1 ALOX5 ALOX15	1.54e-04	22	109	3	CID000051550
Drug	cediranib	CALR CALU MTOR	1.54e-04	22	109	3	CID009933475
Drug	AC1NBU2J	PPL PTPN9 PCSK4	1.54e-04	22	109	3	CID004473762
Drug	9,12,15-octadecatrienoic acid	CALR LCT FLAD1 PRKCA ALOX5 ALOX15	1.54e-04	167	109	6	CID000000860
Drug	L-656,224	PRKCA ALOX5 ALOX15	1.76e-04	23	109	3	CID000128132
Drug	HA1004	FN1 PLD3 PRKCA NID1 PLD1	1.80e-04	109	109	5	CID000003546
Drug	1,2,5,6-dibenzanthracene	COL4A2 ABCA1 SLC2A9 FN1 TNFSF10 PLCD4 PPL ADPRH PTPN9 LGI2 MMP8 CDC20 PCSK4	1.84e-04	837	109	13	ctd:C026486
Drug	Fructose	CYBB ABCA1 SLC2A9 ACACA LCT MSN ENTPD2	1.84e-04	246	109	7	ctd:D005632
Drug	nitric oxide	CYBB FN1 ATE1 PLD3 RYR2 MMP24 CLEC4F FCN2 PRKCA PLD1 MMP8 MMP11 MMP17 ALOX5 ALOX15	1.86e-04	1075	109	15	CID000145068
Drug	Endocrine Disruptors	ACACA RAD54L2 PRKCA PLD1 GPNMB	1.88e-04	110	109	5	ctd:D052244
Drug	6-trans-leukotriene B4	FN1 PLCD4 PLD3 PRKCA PLD1 ALOX5 ALOX15	1.89e-04	247	109	7	CID000000169
Drug	monomethyl phthalate	CYP2A13 ABCA1 LARP1 PLCD4 H6PD PPL MSN USP4 CDC20 MMP17 KDM6A ALOX5 TENT2 HTT	1.91e-04	957	109	14	ctd:C517284
Drug	nilvadipine	RYR2 NID1 CACNA1G CACNA2D3	1.97e-04	60	109	4	CID000004494
Disease	pantothenate measurement	ABCA1 TENM2 DFFB	2.49e-06	8	106	3	EFO_0021034
Disease	spermatogenesis-associated protein 20 measurement	SPATA20 CACNA1G	1.28e-05	2	106	2	EFO_0802083
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	TNFSF10 LRP1B MTOR MUC4 KDM6A ALOX5	1.62e-05	148	106	6	C0279702
Disease	Neoplasm of uncertain or unknown behavior of bladder	MTOR KDM6A STAG2	1.99e-05	15	106	3	C0496930
Disease	Benign neoplasm of bladder	MTOR KDM6A STAG2	1.99e-05	15	106	3	C0154017
Disease	Carcinoma in situ of bladder	MTOR KDM6A STAG2	1.99e-05	15	106	3	C0154091
Disease	Carcinoma of bladder	MTOR KDM6A STAG2	3.54e-05	18	106	3	C0699885
Disease	coronary artery calcification	COL4A2 ABCA1 GRM5 LRP1B PTPRM MYLIP PRKCA POFUT2 CACNA2D3	3.67e-05	450	106	9	EFO_0004723
Disease	Kabuki syndrome (implicated_via_orthology)	KDM6A UTY	3.83e-05	3	106	2	DOID:0060473 (implicated_via_orthology)
Disease	rectum adenocarcinoma (is_marker_for)	SLC7A5 KDM6A	3.83e-05	3	106	2	DOID:1996 (is_marker_for)
Disease	Colorectal Carcinoma	ABCA1 ACACA FN1 TNFSF10 CALR FCN2 TENM1 NID1 GPNMB MMP11 KDM6A	4.59e-05	702	106	11	C0009402
Disease	exercise test	RDX RYR2 PRKCA	4.91e-05	20	106	3	EFO_0004328
Disease	Glioblastoma Multiforme	FN1 TNFSF10 MTOR PRKCA STAG2	5.15e-05	111	106	5	C1621958
Disease	renal fibrosis (is_marker_for)	CYBB ADAM17	7.63e-05	4	106	2	DOID:0050855 (is_marker_for)
Disease	Sarcomatoid Renal Cell Carcinoma	TNFSF10 LRP1B MTOR MUC4 ALOX5	1.01e-04	128	106	5	C1266043
Disease	Chromophobe Renal Cell Carcinoma	TNFSF10 LRP1B MTOR MUC4 ALOX5	1.01e-04	128	106	5	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	TNFSF10 LRP1B MTOR MUC4 ALOX5	1.01e-04	128	106	5	C1266044
Disease	Papillary Renal Cell Carcinoma	TNFSF10 LRP1B MTOR MUC4 ALOX5	1.01e-04	128	106	5	C1306837
Disease	Renal Cell Carcinoma	TNFSF10 LRP1B MTOR MUC4 ALOX5	1.01e-04	128	106	5	C0007134
Disease	Liver Cirrhosis, Experimental	CYBB COL4A2 ERAP1 MSN CLEC4F ANGPTL3 NID1 ADAM17 GPNMB MMP8 PLOD2	1.09e-04	774	106	11	C0023893
Disease	1-myristoyl-2-docosahexaenoyl-GPC (14:0/22:6) measurement	GREB1L MIB1	1.27e-04	5	106	2	EFO_0800454
Disease	severe acute respiratory syndrome, COVID-19	COL4A2 LRP1B TENM2 ADAMTS12 MALRD1 PRKCA KCNIP4 CACNA2D3	2.15e-04	447	106	8	EFO_0000694, MONDO_0100096
Disease	endometrial carcinoma (is_marker_for)	ERAP1 PRKCA MMP8	2.49e-04	34	106	3	DOID:2871 (is_marker_for)
Disease	colon cancer (is_implicated_in)	CALR LRP1B SLC7A5	2.95e-04	36	106	3	DOID:219 (is_implicated_in)
Disease	severe pre-eclampsia (is_marker_for)	COL4A2 ERAP1	3.53e-04	8	106	2	DOID:13129 (is_marker_for)
Disease	triacylglycerol 58:6 measurement	LRP1B TENM2	3.53e-04	8	106	2	EFO_0010440
Disease	asthma exacerbation measurement	GRM5 TENM2 MALRD1 PTPRM	3.59e-04	93	106	4	EFO_0007614
Disease	hepatocellular carcinoma (is_implicated_in)	CALR TEP1 LRP1B SLC7A5 KDM6A	5.05e-04	181	106	5	DOID:684 (is_implicated_in)
Disease	congestive heart failure (biomarker_via_orthology)	PRKCA ADAM17 MMP8 ALOX15	6.11e-04	107	106	4	DOID:6000 (biomarker_via_orthology)
Disease	Hypertensive disease	CYBB FN1 ERAP1 MTOR ALOX15	6.29e-04	190	106	5	C0020538
Disease	Early Pregnancy Loss	FN1 TNFSF10 MMP11 MUC4	6.55e-04	109	106	4	C3830362
Disease	Malignant mesothelioma	FN1 RYR2 SETDB1 FCN2	6.55e-04	109	106	4	C0345967
Disease	Spontaneous abortion	FN1 TNFSF10 MMP11 MUC4	6.55e-04	109	106	4	C0000786
Disease	Miscarriage	FN1 TNFSF10 MMP11 MUC4	6.55e-04	109	106	4	C4552766
Disease	Abortion, Tubal	FN1 TNFSF10 MMP11 MUC4	6.55e-04	109	106	4	C0000822
Disease	alcohol use disorder (implicated_via_orthology)	RYR2 ANGPTL3 PRKCA KDM6A UTY	7.07e-04	195	106	5	DOID:1574 (implicated_via_orthology)
Disease	Hepatic fibrosis	CYP2A13 SDK2 ATP12A	7.36e-04	49	106	3	HP_0001395
Disease	malignant pleural mesothelioma (is_marker_for)	SLC7A5 KDM6A	1.13e-03	14	106	2	DOID:7474 (is_marker_for)
Disease	Hermansky-Pudlak syndrome (implicated_via_orthology)	CCZ1B CCZ1	1.13e-03	14	106	2	DOID:3753 (implicated_via_orthology)
Disease	hypertension (implicated_via_orthology)	FN1 MTOR PRKCA ALOX5	1.19e-03	128	106	4	DOID:10763 (implicated_via_orthology)
Disease	Atherosclerosis	ABCA1 ALOX5 ALOX15	1.27e-03	59	106	3	C0004153
Disease	Atherogenesis	ABCA1 ALOX5 ALOX15	1.27e-03	59	106	3	C1563937
Disease	body mass index, type 2 diabetes mellitus	IGF2BP2 MTOR	1.48e-03	16	106	2	EFO_0004340, MONDO_0005148
Disease	gout, hyperuricemia	SLC2A9 MALRD1	1.48e-03	16	106	2	EFO_0004274, EFO_0009104
Disease	cholangiocarcinoma (is_marker_for)	SLC7A5 MUC4 ALOX5	1.60e-03	64	106	3	DOID:4947 (is_marker_for)
Disease	diverticular disease	KREMEN1 ATE1 ARFRP1 PRMT2 KCNIP4	1.65e-03	236	106	5	EFO_0009959
Disease	Prostatic Neoplasms	TNFSF10 CALR LRP1B PPL SETDB1 MUC4 KDM6A ALOX5	1.73e-03	616	106	8	C0033578
Disease	Malignant neoplasm of prostate	TNFSF10 CALR LRP1B PPL SETDB1 MUC4 KDM6A ALOX5	1.73e-03	616	106	8	C0376358
Disease	glucose homeostasis measurement, acute insulin response measurement	SDK2 PTPRM	1.88e-03	18	106	2	EFO_0006831, EFO_0006896
Disease	physical activity measurement	MARCHF10 ERAP1 CALU GRM5 USP4	1.94e-03	245	106	5	EFO_0008002
Disease	portal hypertension (implicated_via_orthology)	MTOR ALOX5	2.10e-03	19	106	2	DOID:10762 (implicated_via_orthology)
Disease	Cannabis use, age at onset	LARP1 RYR2	2.10e-03	19	106	2	EFO_0004847, EFO_0007585
Disease	stomach cancer (is_implicated_in)	TEP1 LRP1B KDM6A	2.24e-03	72	106	3	DOID:10534 (is_implicated_in)
Disease	dilated cardiomyopathy	PRKCA GPNMB	2.33e-03	20	106	2	EFO_0000407
Disease	lung cancer (is_implicated_in)	CALR LRP1B SETDB1	2.43e-03	74	106	3	DOID:1324 (is_implicated_in)
Disease	transient cerebral ischemia (biomarker_via_orthology)	DFFB MTOR ENTPD1 HTT	2.52e-03	157	106	4	DOID:224 (biomarker_via_orthology)
Disease	psoriasis, type 2 diabetes mellitus	ERAP1 RDX IGF2BP2	2.52e-03	75	106	3	EFO_0000676, MONDO_0005148
Disease	DNA methylation	ABCA1 KREMEN1 SLC2A9 LRP1B PTPRM ENTPD1 KCNIP4 CACNA2D3	2.56e-03	656	106	8	GO_0006306
Disease	susceptibility to scarlet fever measurement	SDK2 FRYL ATE1	2.92e-03	79	106	3	EFO_0008409
Disease	Glioblastoma	FN1 TNFSF10 MTOR	2.92e-03	79	106	3	C0017636
Disease	pulmonary hypertension (biomarker_via_orthology)	CYBB RYR2 ALOX5	3.03e-03	80	106	3	DOID:6432 (biomarker_via_orthology)
Disease	type 2 diabetes mellitus (is_implicated_in)	ABCA1 IGF2BP2 MTOR ADAM17	3.42e-03	171	106	4	DOID:9352 (is_implicated_in)
Disease	Giant Cell Glioblastoma	FN1 TNFSF10 MTOR	3.48e-03	84	106	3	C0334588

Protein segments in the cluster

Peptide	Gene	Start	Entry
FLLQQGYSDGYTKWD	USP26	266	Q9BXU7
TWQDEEYFGSYGTLK	PRMT2	96	P55345
GEYISSVAWIKEGNY	CDC20	226	Q12834
YSTINYKWSFGDNTG	GPNMB	276	Q14956
SLNWYEDNNYKALFG	ABCA1	321	O95477
GSYLDDEKNWGLSFY	ORM2	131	P19652
LWSGYSLLYFEGQEK	COL4A2	1511	P08572
QKGQWLSGFFDYGSF	ACACA	1946	Q13085
LLGFLKYYATEFDWN	TENT2	391	Q6PIY7
DGLVSWEEYKNATYG	CALU	121	O43852
NETWENYKYGFGRLD	ANGPTL3	296	Q9Y5C1
WEYFYGLLFTSENLK	DFFB	286	O76075
TYEWAKDLLTNYQTG	RAD54L2	701	Q9Y4B4
KGVAYALWDYEAQNS	PPP1R13B	1021	Q96KQ4
KDWYLNLNYGGASNF	ATP8A1	326	Q9Y2Q0
WNGNYKLAGTVFQYD	ADAMTS12	761	P58397
IFLFKGNQYWALSGY	MMP8	341	P22894
EGLLYAWGANTYGQL	RCBTB1	251	Q8NDN9
ENLGNWQKEFIYYAD	RAB9B	96	Q9NP90
GGYVKIDLATWNFQF	PTPN9	236	P43378
SGYNAWLSYELQLGT	PCDHA2	601	Q9Y5H9
EVWFFGLQYVDSKGY	RDX	41	P35241
EAPFAGQNWLKSYGY	MMP24	76	Q9Y5R2
SYALFLYQSGGMQWD	MUC4	4481	Q99102
KIFEAYWFLGQAGSS	PLD3	246	Q8IV08
DYEAGQLYGLEKFWA	LARP1	981	Q6PKG0
KDYFDYINVGSWDNG	GRM5	476	P41594
DYVENKLYWISSGNG	LRP1B	1741	Q9NZR2
KGYEAQTFNWENYLE	L3MBTL2	501	Q969R5
NDLKDSYGQEWTRYQ	ATP12A	911	P54707
SLQSDYWKNAAFLYG	KDM6A	121	O15550
GYSGLYEAIESWDFK	DDX58	81	O95786
VTANYLLENFIKYGW	ENTPD2	171	Q9Y5L3
AQSTEGWDFLYSKYQ	ERAP1	776	Q9NZ08
VWTLGLENKGYYFNT	PCSK4	551	Q6UW60
DNGYKVYWETGAQIT	PGM2L1	181	Q6PCE3
YSYTLQKNNGESWEL	PPL	421	O60437
VGFLWKSNGAYNIFA	NID1	226	P14543
FNWDGYYKEVGSAFI	ENDOU	336	P21128
GLSSDGYLYKWLDNI	FRYL	1126	O94915
LNWAFNLYDINKDGY	KCNIP4	161	Q6PIL6
VSYSLNGKDWEYIQD	NRP2	526	O60462
LFAYGGWNYLNFVTE	SLC7A5	251	Q01650
SWKEDALFGYQFLNG	ALOX15	221	P16050
NFEWLNGYTVKFGLY	LCT	1321	P09848
YFGLQFTGSKGESLW	MYLIP	41	Q8WY64
NNPDYWKYGEAASTE	KREMEN1	171	Q96MU8
EVWFFGLQYQDTKGF	MSN	41	P26038
LKSGYAFVDYPDQNW	IGF2BP2	36	Q9Y6M1
AYGWITINYLLGKFS	ENTPD1	176	P49961
LYFGLSEYSKSLQWG	GREB1L	861	Q9C091
YFNYTVKVLGQGEEW	PLOD2	61	O00469
LALNYYKEAGLWSDA	IFT172	1231	Q9UG01
SAAYVLWDNGAKNLY	MIB1	191	Q86YT6
WYLYADSSNGKFGDT	MALRD1	1146	Q5VYJ5
LGGQEELQSLWDKYY	ARFRP1	76	Q13795
YWSKLNDLFGDAALY	HTT	2201	P42858
LTGIYFAFYNGEWDL	FAM126A	241	Q9BYI3
TFDWLFKGYGVAFSN	CYP2A13	106	Q16696
FKGAINFDNIGYAWI	CACNA1G	331	O43497
GAVDTYDTIFAKYNW	CACNA2D3	371	Q8IZS8
GSVDFYRDWATYKQG	FCN2	151	Q15485
TGTFYQIGDSWEKYV	FN1	566	P02751
KYTAFLYNDQLIWSG	CCZ1	221	P86791
YAYDNFGVLGLDLWQ	CALR	306	P27797
KYTAFLYNDQLIWSG	CCZ1B	221	P86790
SEGYWKDYLNSSQNS	MARCHF10	436	Q8NA82
GYGSFHQQYWLDGKI	ATE1	336	O95260
AGFLSYNIYLTGWDE	CYBB	471	P04839
GLNAIWFYTNSIFGK	SLC2A9	331	Q9NRM0
GWFVLYYEDLLGDQA	EBP	81	Q15125
WGSNYYQVKLTLDSE	FLAD1	316	Q8NFF5
YLWQGLFQLYLDEAG	H6PD	41	O95479
SQNGDIQGYKIYFWE	SDK2	1651	Q58EX2
KLANGWIYGEIYSDS	RYR2	2736	Q92736
LYDWAAGKLYQGQVD	NLRP6	216	P59044
FTIGDNKTYNGYWNT	PTPRM	676	P28827
SGNVKDLTQAWDLYY	MTOR	2091	P42345
FFQGAQYWVYDGEKP	MMP11	356	P24347
ADYWKNAAFLYGLGL	UTY	121	O14607
NSGQYWLSLLDSYAG	SLC6A19	476	Q695T7
QDLDTVWSLGGYLQY	TMC3	191	Q7Z5M5
YDWKSRNDFIGQYTL	PLCD4	706	Q9BRC7
WEELSSQLFYYGGEL	TMEM191C	151	A6NGB0
ASGWYKLLNQEEGEY	PRKCA	271	P17252
GSQWFAGTDDYIYLS	ALOX5	11	P09917
GSDYTFSQIYQWDKE	LGI2	481	Q8N0V4
QVYVLQSYAEGWKEG	POFUT2	136	Q9Y2G5
SDGASYFFRGQEYWK	MMP17	486	Q9ULZ9
GSYAAIQENALAKWY	PLD1	341	Q13393
WGGSGSYFNNLDYLL	FAM178B	191	Q8IXR5
NLVYTFAWNKTDIYG	TENM1	1076	Q9UKZ4
WDKTDAYGQRVYGLS	TENM2	1126	Q9NT68
LTWDYNYEVGSVEGK	SETDB1	1261	Q15047
IYRNTSWDNAGFKGY	ADAM17	261	P78536
ALGYYNGKWEFLQDG	ADPRH	16	P54922
QGWKFNGGSLYYFSS	CLEC4F	471	Q8N1N0
YQLLGIKSIGFEWNY	ZG16B	171	Q96DA0
NGKWYYFDDSNVSLA	USP4	891	Q13107
SQGLWSDYSDNLKYD	ZNF250	91	P15622
ENDGWSLNTFGKYLL	TEP1	756	Q99973
DAFLNDSYLKYVGWT	STAG2	321	Q8N3U4
TQDKLFWDSQGGGYF	SPATA20	606	Q8TB22
KLYSYSLQGYSWLGE	TMEM214	531	Q6NUQ4
GLYADYLFNAIAGNW	TRABD2A	146	Q86V40
TWGNYGKSYSVALYL	PIAS4	261	Q8N2W9
QALVAQYGDWFSYDG	PLBD2	441	Q8NHP8
WDYLIGNSETADNKY	TMC2	386	Q8TDI7
YLQGALKNYLAEGWA	TRAPPC10	501	P48553
WSKDAEYGLYSIYQG	TNFSF10	231	P50591
AQWFYEYGNALEGST	ZNF7	606	P17097
DSASNYFPWYKQELG	TRAV13-1	46	A0A0B4J241