Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	oxidoreductase activity, acting on CH or CH2 groups	CYP3A4 CYP3A43 XDH	1.47e-04	15	141	3	GO:0016725
GeneOntologyMolecularFunction	testosterone 16-alpha-hydroxylase activity	CYP3A4 CYP3A43	2.94e-04	4	141	2	GO:0008390
GeneOntologyMolecularFunction	testosterone 6-beta-hydroxylase activity	CYP3A4 CYP3A43	4.88e-04	5	141	2	GO:0050649
GeneOntologyMolecularFunction	vitamin D 23-hydroxylase activity	CYP3A4 CYP3A43	4.88e-04	5	141	2	GO:0062179
GeneOntologyMolecularFunction	1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity	CYP3A4 CYP3A43	4.88e-04	5	141	2	GO:0062181
GeneOntologyMolecularFunction	vitamin D3 25-hydroxylase activity	CYP3A4 CYP3A43	7.29e-04	6	141	2	GO:0030343
GeneOntologyMolecularFunction	vitamin D 24-hydroxylase activity	CYP3A4 CYP3A43	7.29e-04	6	141	2	GO:0070576
GeneOntologyMolecularFunction	vitamin D 25-hydroxylase activity	CYP3A4 CYP3A43	1.02e-03	7	141	2	GO:0070643
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HIVEP1 HIVEP2 HDAC4 ESR1 SOX30 ZNF397 REST SKI ZKSCAN5 TFCP2L1 ZSCAN20 WIZ ZNF296 KLF5 NR5A1 ATF4 ZNF853 CUX1 NR1D2	1.21e-03	1244	141	19	GO:0000978
GeneOntologyMolecularFunction	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor	CYP3A4 CYP3A43	1.35e-03	8	141	2	GO:0033695
GeneOntologyMolecularFunction	caffeine oxidase activity	CYP3A4 CYP3A43	1.35e-03	8	141	2	GO:0034875
GeneOntologyMolecularFunction	estrogen 2-hydroxylase activity	CYP3A4 CYP3A43	1.35e-03	8	141	2	GO:0101021
Domain	SANT	TRERF1 SMARCA5 MYSM1 ZSCAN20 SMARCC1	3.68e-05	50	141	5	SM00717
Domain	SANT_dom	TRERF1 SMARCA5 MYSM1 SMARCC1	4.09e-05	26	141	4	IPR017884
Domain	SANT/Myb	TRERF1 SMARCA5 MYSM1 ZSCAN20 SMARCC1	4.46e-05	52	141	5	IPR001005
Domain	SANT	TRERF1 SMARCA5 MYSM1 SMARCC1	5.54e-05	28	141	4	PS51293
Domain	Myb_DNA-binding	TRERF1 SMARCA5 MYSM1 SMARCC1	1.36e-04	35	141	4	PF00249
Domain	Tyr_Pase_KIM-con	PTPN7 PTPRR	1.69e-04	3	141	2	IPR008356
Domain	MYB_LIKE	TRERF1 SMARCA5 MYSM1 SMARCC1	1.88e-04	38	141	4	PS50090
Domain	Aldolase_II	ADD1 ADD3	3.36e-04	4	141	2	SM01007
Domain	Aldolase_II/adducin_N	ADD1 ADD3	3.36e-04	4	141	2	IPR001303
Domain	Aldolase_II	ADD1 ADD3	3.36e-04	4	141	2	PF00596
Domain	-	ADD1 ADD3	3.36e-04	4	141	2	3.40.225.10
Domain	S_TKc	HUNK TEK ERN2 SCYL2 TTBK1 NRK EIF2AK1 MAP2K3 MAP2K6 CDK7	4.04e-04	359	141	10	SM00220
Domain	Cyt_P450_E_grp-II	CYP3A4 CYP3A43	5.58e-04	5	141	2	IPR002402
Domain	Cyt_P450_E_CYP3A	CYP3A4 CYP3A43	8.32e-04	6	141	2	IPR008072
Domain	SWIRM	MYSM1 SMARCC1	8.32e-04	6	141	2	PS50934
Domain	SWIRM	MYSM1 SMARCC1	8.32e-04	6	141	2	PF04433
Domain	SWIRM	MYSM1 SMARCC1	8.32e-04	6	141	2	IPR007526
Domain	Kinase-like_dom	HUNK TEK ERN2 SCYL2 TTBK1 DST NRK SMARCC1 EIF2AK1 MAP2K3 MAP2K6 CDK7	8.46e-04	542	141	12	IPR011009
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SMARCA5 MAP1B TCOF1 WDR33 PUF60 ERC1 ADD1 ADD3 SCYL2 KIAA1671 CEP170 WIZ SEC24B SEC16A SMARCC1 CUX1 PCMT1	1.67e-10	549	145	17	38280479
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	NUP50 SMARCA5 MAP1B TCOF1 PUF60 ERC1 ESD PPP6R1 NUDCD3 RRBP1 ADD1 ADD3 SCYL2 KIAA1671 CEP170 CRACD DST WIZ SEC24B SEC16A PCMT1	3.70e-10	934	145	21	33916271
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	TRERF1 SMARCA5 ANKFY1 HIVEP1 ESR1 ZNF397 REST TFCP2L1 ZSCAN20 WIZ ZNF296 BTBD7 KLF5 SMARCC1 UNK ATF4 CUX1 NR1D2	8.54e-09	808	145	18	20412781
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	ERC1 PPP6R1 RRBP1 ADD1 ADD3 KIAA1671 DST EIF4ENIF1 SEC16A UNK	2.02e-08	209	145	10	36779422
Pubmed	Interaction network of human early embryonic transcription factors.	TRERF1 SMARCA5 HIVEP1 HIVEP2 HDAC4 SKI KIAA1671 WIZ SEC16A SMARCC1 CDH1 RAI1	3.15e-08	351	145	12	38297188
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	HIVEP2 TCOF1 ERC1 USP11 DNER QRICH1 HUNK RRBP1 ZKSCAN5 ADD3 SCYL2 ARHGAP1 FRY SARS2 DST WIZ RALBP1 LRP1 EIF2AK1 CUX1 NR1D2	9.43e-08	1285	145	21	35914814
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	WDR33 TBC1D22B CCNA2 SCYL2 CEP170 ARHGAP1 DST SEC16A MAP2K3 CUX1 GOLGA4 PCMT1 CDK7	1.02e-07	472	145	13	38943005
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TRERF1 ANKFY1 HDAC4 TCOF1 ERC1 PPP6R1 ADD1 CEP170 FRY DST WIZ SEC16A LRP1 SMARCC1 RABGEF1 CUX1 GOLGA4 RAI1	1.20e-07	963	145	18	28671696
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TRERF1 ANKFY1 HIVEP1 ERC1 PPP6R1 KIAA1671 DST WIZ EIF4ENIF1 SEC16A LRP1 CUX1	2.08e-07	418	145	12	34709266
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SMARCA5 TUT4 TCOF1 ERC1 USP11 PPP6R1 SKI ZKSCAN5 KIAA1671 CEP170 WIZ EIF4ENIF1 SETD5 CAPRIN2 SEC16A LRP1 SMARCC1 CDH16 RAI1	2.20e-07	1116	145	19	31753913
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CPAMD8 TUT4 HIVEP2 HDAC4 MAP1B CERS6 NUDCD3 ZSWIM1 RRBP1 SKI KIAA1671 CEP170 LRFN2 SETD5 PTPRR LRP1 MAP2K3 CLEC16A CUX1 GOLGA4 MAN1B1 RAI1	2.56e-07	1489	145	22	28611215
Pubmed	A census of human transcription factors: function, expression and evolution.	TRERF1 HIVEP1 HIVEP2 ESR1 SOX30 ESX1 CERS6 REST TSC22D2 SKI MYSM1 TFCP2L1 ZSCAN20 KLF5 NR5A1 ATF4 NR1D2	2.71e-07	908	145	17	19274049
Pubmed	The functional interactome landscape of the human histone deacetylase family.	TRERF1 NUP50 HDAC4 WDR33 PUF60 ESD PPP6R1 ADD3 SEC16A SMARCC1	4.13e-07	289	145	10	23752268
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	HDAC4 ERC1 TBC1D22B PPP6R1 KIAA1671 CEP170 DST EIF4ENIF1 SEC16A UNK RABGEF1 IPO11	4.15e-07	446	145	12	24255178
Pubmed	Human transcription factor protein interaction networks.	TRERF1 SMARCA5 HIVEP1 WDR33 USP11 ESR1 PPP6R1 SKI CCNA2 KIAA1671 DST WIZ EIF4ENIF1 KLF5 UBXN7 SEC24B SEC16A SMARCC1 UNK CUX1 PCMT1	5.39e-07	1429	145	21	35140242
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	TCOF1 TBC1D22B ADD1 ADD3 SEMA4C KIAA1671 ARHGAP1 DST WIZ SEC24B SEC16A CLEC16A PCDH9 CUX1 GOLGA4	9.77e-07	777	145	15	35844135
Pubmed	The protein interaction landscape of the human CMGC kinase group.	NUP50 TCOF1 TROAP WDR33 ERC1 USP11 SKI TEK ECM1 CCNA2 FRY NSG1 MAP2K3 CDK7	1.40e-06	695	145	14	23602568
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	NUP50 SMARCA5 ANKFY1 ARHGAP40 WDR33 PUF60 NOA1 TIAM2 KIAA1671 CEP170 ARHGAP1 RALBP1 SEC16A SMARCC1 GOLGA4 PCMT1	1.54e-06	916	145	16	32203420
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	NUP50 SMARCA5 TCOF1 PUF60 ESD ADD1 ADD3 CRACD DST WIZ SMARCC1 CDK7	1.55e-06	506	145	12	30890647
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	TCOF1 ESR1 TEK SCYL2 CEP170 PTPN7 PTPRR PPM1L SEC16A LRP1 RABGEF1	1.66e-06	420	145	11	28065597
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	ANKFY1 HIVEP1 HIVEP2 ESR1 QRICH1 REST ZKSCAN5 ZFAND4 TFCP2L1 KLF5 SMARCC1 ATF4 CUX1 NR1D2	1.76e-06	709	145	14	22988430
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TRERF1 HIVEP1 WDR33 SKI WIZ KLF5 SMARCC1 CUX1 RAI1	2.04e-06	268	145	9	33640491
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	TUT4 MAP1B ERC1 RRBP1 ADD1 CEP170 ARHGAP1 PARP4 WIZ EIF4ENIF1 SMARCC1 UNK MAP2K3 PCMT1	2.25e-06	724	145	14	36232890
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	MPO TRERF1 NUP50 HIVEP1 HDAC4 PUF60 QRICH1 CEP170 PRAM1 WIZ KLF5 SMARCC1 CUX1 PCMT1 RAI1 IPO11 CDK7	3.81e-06	1103	145	17	34189442
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	PUF60 ERC1 TBC1D22B ADD1 ADD3 SCYL2 KIAA1671 ARHGAP1 DST SEC24B CDH1 PCMT1	4.80e-06	565	145	12	25468996
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ANKFY1 ERC1 PPP6R1 CRACD LRFN2 SETD5 BTBD7 SEC16A KIF17 CLEC16A	8.75e-06	407	145	10	12693553
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	TRERF1 HDAC4 TCOF1 ESR1 TSC22D2 ZKSCAN5 KIAA1671 EIF4ENIF1 KLF5 UNK	1.41e-05	430	145	10	35044719
Pubmed	The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.	WDR33 ERC1 PPP6R1 SEMA4C PARP4 SEC16A	1.48e-05	125	145	6	29467281
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	SMARCA5 MAP1B PUF60 USP11 PPP6R1 QRICH1 RRBP1 SKI CRACD WIZ LRP1 SMARCC1 MAP2K3 CUX1	1.52e-05	857	145	14	25609649
Pubmed	The frameshift polymorphism CYP3A43_74_delA is associated with poor differentiation of breast tumors.	CYP3A4 CYP3A43	1.73e-05	2	145	2	20715157
Pubmed	Effects of genetic variation in adducin on left ventricular diastolic function as assessed by tissue Doppler imaging in a Flemish population.	ADD1 ADD3	1.73e-05	2	145	2	18475162
Pubmed	Differential roles of MAPK kinases MKK3 and MKK6 in osteoclastogenesis and bone loss.	MAP2K3 MAP2K6	1.73e-05	2	145	2	24400116
Pubmed	Differences in E-Cadherin and Syndecan-1 Expression in Different Types of Ameloblastomas.	CDH1 SDC1	1.73e-05	2	145	2	29850393
Pubmed	Estrogen-induced interaction between KLF5 and estrogen receptor (ER) suppresses the function of ER in ER-positive breast cancer cells.	ESR1 KLF5	1.73e-05	2	145	2	19569049
Pubmed	MKK3, an upstream activator of p38, contributes to formalin phase 2 and late allodynia in mice.	MAP2K3 MAP2K6	1.73e-05	2	145	2	19427893
Pubmed	CCAAT-displacement protein/cut homeobox transcription factor (CUX1) represses estrogen receptor-alpha (ER-α) in triple-negative breast cancer cells and can be antagonized by muscadine grape skin extract (MSKE).	ESR1 CUX1	1.73e-05	2	145	2	30964885
Pubmed	Microtubule stability, Golgi organization, and transport flux require dystonin-a2-MAP1B interaction.	MAP1B DST	1.73e-05	2	145	2	22412020
Pubmed	Cytohesin-associated scaffolding protein (CASP) is a substrate for granzyme B and ubiquitination.	GZMB CUX1	1.73e-05	2	145	2	25159843
Pubmed	Btbd7 contributes to reduced E-cadherin expression and predicts poor prognosis in non-small cell lung cancer.	BTBD7 CDH1	1.73e-05	2	145	2	25253020
Pubmed	Differential involvement of p38 mitogen-activated protein kinase kinases MKK3 and MKK6 in T-cell apoptosis.	MAP2K3 MAP2K6	1.73e-05	2	145	2	12151339
Pubmed	Increased expression of phosphorylated adducin in tumor cells.	ADD1 ADD3	1.73e-05	2	145	2	32237935
Pubmed	Expression of syndecan-1 and E-cadherin is inversely correlated with poor patient's prognosis and recurrent status of extrahepatic bile duct carcinoma.	CDH1 SDC1	1.73e-05	2	145	2	19420730
Pubmed	MYSM1 inhibits human colorectal cancer tumorigenesis by activating miR-200 family members/CDH1 and blocking PI3K/AKT signaling.	MYSM1 CDH1	1.73e-05	2	145	2	34706761
Pubmed	New markers: urine xanthine oxidase and myeloperoxidase in the early detection of urinary tract infection.	MPO XDH	1.73e-05	2	145	2	24591758
Pubmed	A genetic variant near the PMAIP1/Noxa gene is associated with increased bleomycin sensitivity.	NOA1 REST	1.73e-05	2	145	2	21106707
Pubmed	ERalpha as ligand-independent activator of CDH-1 regulates determination and maintenance of epithelial morphology in breast cancer cells.	ESR1 CDH1	1.73e-05	2	145	2	19383788
Pubmed	E-cadherin adhesion molecule and syndecan-1 expression in various thyroid pathologies.	CDH1 SDC1	1.73e-05	2	145	2	17431390
Pubmed	Role of MAPK kinase 6 in arthritis: distinct mechanism of action in inflammation and cytokine expression.	MAP2K3 MAP2K6	1.73e-05	2	145	2	19561096
Pubmed	Overexpression of ZNF342 by juxtaposition with MPO promoter/enhancer in the novel translocation t(17;19)(q23;q13.32) in pediatric acute myeloid leukemia and analysis of ZNF342 expression in leukemia.	MPO ZNF296	1.73e-05	2	145	2	19255975
Pubmed	Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression.	MAP2K3 MAP2K6	1.73e-05	2	145	2	10097111
Pubmed	Simultaneous loss of expression of syndecan-1 and E-cadherin in the embryonic palate during epithelial-mesenchymal transformation.	CDH1 SDC1	1.73e-05	2	145	2	9712528
Pubmed	Expression of oestrogen receptor and loss of E-cadherin are diagnostic for gastric metastasis of breast carcinoma.	ESR1 CDH1	1.73e-05	2	145	2	15693887
Pubmed	Adducins regulate remodeling of apical junctions in human epithelial cells.	ADD1 ADD3	1.73e-05	2	145	2	20810786
Pubmed	Loss of E-cadherin-mediated cell contacts reduces estrogen receptor alpha (ER alpha) transcriptional efficiency by affecting the respective contribution exerted by AF1 and AF2 transactivation functions.	ESR1 CDH1	1.73e-05	2	145	2	17991426
Pubmed	Recruitment of histone deacetylase 4 to the N-terminal region of estrogen receptor alpha.	HDAC4 ESR1	1.73e-05	2	145	2	16051668
Pubmed	HDAC4 protects cells from ER stress induced apoptosis through interaction with ATF4.	HDAC4 ATF4	1.73e-05	2	145	2	24308964
Pubmed	Specific calcineurin targeting in macrophages confers resistance to inflammation via MKP-1 and p38.	MAP2K3 MAP2K6	1.73e-05	2	145	2	24596247
Pubmed	SUMOylation inhibits SF-1 activity by reducing CDK7-mediated serine 203 phosphorylation.	NR5A1 CDK7	1.73e-05	2	145	2	19015234
Pubmed	Phosphorylation of steroidogenic factor 1 is mediated by cyclin-dependent kinase 7.	NR5A1 CDK7	1.73e-05	2	145	2	17901130
Pubmed	Cis-acting regulatory elements regulating CYP3A4 transcription in human liver.	CYP3A4 CYP3A43	1.73e-05	2	145	2	32301865
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	MPO NUP50 MAP1B QRICH1 ADD3 PAPOLG CEP170 SEC24B SEC16A CDK7	1.85e-05	444	145	10	34795231
Pubmed	Sequence diversity and haplotype structure at the human CYP3A cluster.	CYP3A4 CYP3A43 ZKSCAN5	1.97e-05	13	145	3	16314882
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	DNER HUNK SKI TEK FRY PTPRR USH2A	2.14e-05	199	145	7	23382691
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TRERF1 SMARCA5 HIVEP1 TCOF1 REST RRBP1 ADD1 PAPOLG GZMB SEC16A SMARCC1 UNK GOLGA4	2.32e-05	774	145	13	15302935
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	NUP50 SMARCA5 PUF60 USP11 ESD QRICH1 RRBP1 CCNA2 TFCP2L1 KLF5 UBXN7 SMARCC1 MAP2K3 PCMT1 CDK7	2.36e-05	1014	145	15	32416067
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	NUP50 HDAC4 WDR33 QRICH1 PARP4 EIF4ENIF1 SEC16A SMARCC1 MAP2K6 RAI1	2.37e-05	457	145	10	32344865
Pubmed	Establishment and analysis of a mouse model that regulates sex-related differences in liver drug metabolism.	CYP3A4 CYP3A43 ESR1	3.11e-05	15	145	3	29968852
Pubmed	A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs.	DNER REST CDH1	3.82e-05	16	145	3	35577801
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	HIVEP1 TCOF1 WDR33 ERC1 USP11 PPP6R1 NUDCD3 PAPOLG KIAA1671 SEC16A UNK	3.86e-05	588	145	11	38580884
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	MAP1B TCOF1 ERC1 RRBP1 ADD1 SCYL2 CEP170 ARHGAP1 DST SEC24B SEC16A GOLGA4	4.44e-05	708	145	12	39231216
Pubmed	ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination.	CCNA2 FAT2 CUX1	4.62e-05	17	145	3	26581405
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	MAP1B TCOF1 WDR33 PUF60 ERC1 CEP170 UBXN7 SEC16A SMARCC1	4.84e-05	399	145	9	35987950
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	NUP50 SMARCA5 HIVEP1 MAP1B WDR33 PUF60 RRBP1 CEP170 PRAM1 WIZ SEC16A SMARCC1 CUX1 RAI1	4.87e-05	954	145	14	36373674
Pubmed	p38α Signaling Induces Anoikis and Lumen Formation During Mammary Morphogenesis.	MAP2K3 MAP2K6	5.16e-05	3	145	2	21610252
Pubmed	Downregulation of mouse hepatic CYP3A protein by 3-methylcholanthrene does not require cytochrome P450-dependent metabolism.	CYP3A4 CYP3A43	5.16e-05	3	145	2	23846873
Pubmed	Expression and significance of Twist, estrogen receptor, and E-cadherin in human breast cancer cells and tissues.	ESR1 CDH1	5.16e-05	3	145	2	28901319
Pubmed	Heme-regulated eIF2α kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis.	ATF4 EIF2AK1	5.16e-05	3	145	2	22498744
Pubmed	Changes in the expression of oestrogen receptors and E-cadherin as molecular markers of progression from normal epithelium to invasive cancer in elderly patients with vulvar squamous cell carcinoma.	ESR1 CDH1	5.16e-05	3	145	2	21323952
Pubmed	Regulation of the expression of two female-predominant CYP3A mRNAs (CYP3A41 and CYP3A44) in mouse liver by sex and growth hormones.	CYP3A4 CYP3A43	5.16e-05	3	145	2	12147261
Pubmed	Mouse liver cytochrome P-450 (P-450IIIAM1): its cDNA cloning and inducibility by dexamethasone.	CYP3A4 CYP3A43	5.16e-05	3	145	2	1339292
Pubmed	Predominantly neuronal expression of cytochrome P450 isoforms CYP3A11 and CYP3A13 in mouse brain.	CYP3A4 CYP3A43	5.16e-05	3	145	2	12617959
Pubmed	An essential role for Pax8 in the transcriptional regulation of cadherin-16 in thyroid cells.	CDH1 CDH16	5.16e-05	3	145	2	22135066
Pubmed	MKK3 and -6-dependent activation of p38alpha MAP kinase is required for cytoskeletal changes in pulmonary microvascular endothelial cells induced by ICAM-1 ligation.	MAP2K3 MAP2K6	5.16e-05	3	145	2	15516490
Pubmed	17β-Estradiol-induced cell proliferation requires estrogen receptor (ER) α monoubiquitination.	ESR1 RABGEF1	5.16e-05	3	145	2	21356307
Pubmed	The Critical Role of The Piezo1/β-catenin/ATF4 Axis on The Stemness of Gli1+ BMSCs During Simulated Microgravity-Induced Bone Loss.	PIEZO1 ATF4	5.16e-05	3	145	2	37759400
Pubmed	Collective Wisdom: Lobular Carcinoma of the Breast.	ESR1 CDH1	5.16e-05	3	145	2	27249682
Pubmed	Intergenic mRNA molecules resulting from trans-splicing.	CYP3A4 CYP3A43	5.16e-05	3	145	2	11726664
Pubmed	Activation of mitogen-activated protein kinase kinase (MKK) 3 and MKK6 by type I interferons.	MAP2K3 MAP2K6	5.16e-05	3	145	2	15644321
Pubmed	A diacylglycerol kinase inhibitor, R59022, stimulates glucose transport through a MKK3/6-p38 signaling pathway in skeletal muscle cells.	MAP2K3 MAP2K6	5.16e-05	3	145	2	17588539
Pubmed	Skeletal muscle denervation causes skeletal muscle atrophy through a pathway that involves both Gadd45a and HDAC4.	HDAC4 ATF4	5.16e-05	3	145	2	23941879
Pubmed	High fat diet induced obesity is mitigated in Cyp3a-null female mice.	CYP3A4 CYP3A43	5.16e-05	3	145	2	29738703
Pubmed	A novel female-specific member of the CYP3A gene subfamily in the mouse liver.	CYP3A4 CYP3A43	5.16e-05	3	145	2	10775455
Pubmed	Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases.	PTPN7 PTPRR	5.16e-05	3	145	2	16441242
Pubmed	Concordant up-regulation of cytochrome P450 Cyp3a11, testosterone oxidation and androgen receptor expression in mouse brain after xenobiotic treatment.	CYP3A4 CYP3A43	5.16e-05	3	145	2	19226368
Pubmed	Immunofluorescence localization of an adducin-like protein in the chromosomes of mouse oocytes.	ADD1 ADD3	5.16e-05	3	145	2	1864459
Pubmed	Dynamic patterns of histone methylation are associated with ontogenic expression of the Cyp3a genes during mouse liver maturation.	CYP3A4 CYP3A43	5.16e-05	3	145	2	19188337
Pubmed	Regulation of p38 MAPK by MAPK kinases 3 and 6 in fibroblast-like synoviocytes.	MAP2K3 MAP2K6	5.16e-05	3	145	2	15778394
Pubmed	MAP1B and clathrin are novel interacting partners of the giant cyto-linker dystonin.	MAP1B DST	5.16e-05	3	145	2	21936565
Pubmed	Different roles of estrogen receptors alpha and beta in the regulation of E-cadherin protein levels in a mouse mammary epithelial cell line.	ESR1 CDH1	5.16e-05	3	145	2	18974111
Pubmed	Requirement of protein l-isoaspartyl O-methyltransferase for transcriptional activation of trefoil factor 1 (TFF1) gene by estrogen receptor alpha.	ESR1 PCMT1	5.16e-05	3	145	2	22382029
Interaction	WWTR1 interactions	SMARCA5 MAP1B PUF60 ERC1 ADD3 SCYL2 KIAA1671 CEP170 WIZ KLF5 SEC24B SEC16A SMARCC1 CUX1 PCMT1	2.57e-07	422	140	15	int:WWTR1
Interaction	MAPRE1 interactions	NUP50 MAP1B TROAP ERC1 RRBP1 ADD1 ADD3 CEP170 TTBK1 IFT52 DST RALBP1 SEC16A LRP1 UNK CDH1	5.92e-07	514	140	16	int:MAPRE1
Interaction	HDAC1 interactions	TRERF1 NUP50 SMARCA5 ANKFY1 HIVEP1 ERC1 USP11 ESD ESR1 PPP6R1 REST KIAA1671 TFCP2L1 DST WIZ EIF4ENIF1 RALBP1 KLF5 SMARCC1 CDH1 CUX1 GOLGA4 RAI1 NR1D2	6.34e-07	1108	140	24	int:HDAC1
Interaction	FXR1 interactions	TUT4 ANKFY1 HIVEP1 HDAC4 TCOF1 USP11 ESR1 TBC1D22B ECM1 CCNA2 KIAA1671 CEP170 PRAM1 KIAA1549L EIF4ENIF1 CAPRIN2 SEC16A KIF17	1.15e-06	679	140	18	int:FXR1
Interaction	NAA40 interactions	NUP50 SMARCA5 MAP1B TCOF1 PUF60 ERC1 ESD PPP6R1 NUDCD3 RRBP1 ADD1 ADD3 SCYL2 KIAA1671 CEP170 CRACD DST WIZ SEC24B SEC16A PCMT1	3.99e-06	978	140	21	int:NAA40
Interaction	GSK3A interactions	SMARCA5 WDR33 PUF60 ERC1 PPP6R1 RRBP1 ADD1 ADD3 KIAA1671 DST EIF4ENIF1 KLF5 SEC16A UNK	4.48e-06	464	140	14	int:GSK3A
Interaction	FAM78A interactions	ADD1 ADD3 FAM78A	6.46e-06	6	140	3	int:FAM78A
Interaction	KDM1A interactions	TRERF1 SMARCA5 ANKFY1 HIVEP1 ERC1 ESR1 PPP6R1 ANKRD23 NUDCD3 KIAA1671 TFCP2L1 DST WIZ EIF4ENIF1 SEC16A LRP1 SMARCC1 UNK EIF2AK1 CUX1	8.08e-06	941	140	20	int:KDM1A
Interaction	EBAG9 interactions	ESR1 TBC1D22B ADD1 ADD3 SCYL2 ARHGAP1 DST SEC24B SEC16A CUX1 GOLGA4	9.00e-06	303	140	11	int:EBAG9
Interaction	ACTR3 interactions	ERC1 USP11 ESR1 NUDCD3 DNALI1 KIAA1671 CRACD DST UNK CDH1 CLEC16A	9.57e-06	305	140	11	int:ACTR3
Interaction	CREBBP interactions	TRERF1 HIVEP1 HIVEP2 MAP1B ESR1 CCNA2 EIF4ENIF1 KLF5 SMARCC1 NR5A1 ATF4 CDH1 CUX1 PCMT1 CDK7	1.87e-05	599	140	15	int:CREBBP
Interaction	MAPK1 interactions	HDAC4 ESR1 REST ECM1 PTPN7 PPP2R5B SARS2 PTPRR SEC16A RABGEF1 NR5A1 MAP2K3 MAP2K6 RAI1	2.61e-05	543	140	14	int:MAPK1
Interaction	EGR2 interactions	TRERF1 HIVEP1 HIVEP2 HDAC4 WIZ SEC16A SMARCC1 CDH1	2.63e-05	171	140	8	int:EGR2
Interaction	DYRK1B interactions	TROAP USP11 SKI CCNA2 MAP2K3 CLEC16A	4.14e-05	91	140	6	int:DYRK1B
Interaction	GOLGA1 interactions	ERC1 PPP6R1 KIAA1671 DST SEC16A UNK ATF4 GOLGA4	4.27e-05	183	140	8	int:GOLGA1
Interaction	PPIA interactions	MAP1B WDR33 USP11 ESR1 TBC1D22B RRBP1 CCNA2 SCYL2 CEP170 ARHGAP1 DST SEC16A MAP2K3 MAP2K6 CUX1 GOLGA4 PCMT1 CDK7	4.45e-05	888	140	18	int:PPIA
Interaction	RBBP7 interactions	SMARCA5 HIVEP1 MAP1B TCOF1 USP11 ESR1 REST PTPN7 TFCP2L1 ZNF296 SMARCC1 MAP2K3 GOLGA4	5.44e-05	507	140	13	int:RBBP7
Interaction	AR interactions	TRERF1 DPH1 SMARCA5 HIVEP1 HDAC4 WDR33 PUF60 ESD ESR1 SKI MYSM1 WIZ KLF5 SEC16A SMARCC1 NR5A1 CUX1 RAI1 CDK7	5.76e-05	992	140	19	int:AR
Interaction	PDCD6 interactions	MAP1B ESR1 CCNA2 UBXN7 SEC24B SEC16A SMARCC1 CLEC16A	9.16e-05	204	140	8	int:PDCD6
Interaction	MIDEAS interactions	TRERF1 USP11 ESR1 CCNA2 TFCP2L1 SEC16A	1.08e-04	108	140	6	int:MIDEAS
Interaction	RAB5A interactions	SMARCA5 ANKFY1 HIVEP1 USP11 TBC1D22B RRBP1 SEMA4C SCYL2 ARHGAP1 DST SEC24B SEC16A UNK RABGEF1 PCMT1	1.20e-04	706	140	15	int:RAB5A
Interaction	BRCA1 interactions	SMARCA5 HIVEP1 TCOF1 TROAP ERC1 USP11 ESR1 SOX30 PPP6R1 CCNA2 CEP170 PARP4 DST WIZ SEC24B SEC16A SMARCC1 CDH1 USH2A PCMT1 CDK7	1.46e-04	1249	140	21	int:BRCA1
Interaction	EPHA2 interactions	ANKFY1 TBC1D22B ADD1 ADD3 SEMA4C PTPN7 DST PTPRR SEC24B PPM1L SEC16A MAP2K3 CDH1 MAP2K6 SDC1	1.46e-04	719	140	15	int:EPHA2
Interaction	ARHGAP18 interactions	NEXMIF SCYL2 ARHGAP1 EIF4ENIF1 SEC16A CDH1	1.53e-04	115	140	6	int:ARHGAP18
Interaction	CAV1 interactions	ANKFY1 ESD ESR1 TBC1D22B TEK ADD1 ADD3 ARHGAP1 DST UBXN7 SEC24B LRP1 RABGEF1 CDH1 CUX1	1.58e-04	724	140	15	int:CAV1
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	TRERF1 SMARCA5 MYSM1 ZSCAN20 SMARCC1	6.15e-06	53	89	5	532
GeneFamily	Mitogen-activated protein kinase kinases	MAP2K3 MAP2K6	4.95e-04	7	89	2	653
GeneFamily	Cytochrome P450 family 3	CYP3A4 CYP3A43	6.58e-04	8	89	2	1002
GeneFamily	Maestro heat like repeat containing	MROH5 MROH2B	1.28e-03	11	89	2	636
GeneFamily	Nuclear hormone receptors	ESR1 NR5A1 NR1D2	1.80e-03	49	89	3	71
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	SMARCA5 TUT4 HIVEP1 HIVEP2 HDAC4 MAP1B ERC1 CERS6 TSC22D2 CEP170 DST UBXN7 SEC24B CLEC16A CUX1 GOLGA4 PCMT1	5.49e-06	856	145	17	M4500
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	TUT4 HIVEP1 HIVEP2 MAP1B CERS6 CEP170 DST SEC24B CLEC16A CUX1 GOLGA4 PCMT1	1.16e-05	466	145	12	M13522
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_500	ANKFY1 ESR1 ECM1 MYSM1 ADD1 ADD3 NRK LRP1 SMARCC1 CAPS2 PCDH9 CDH16 CDK7	4.60e-06	413	143	13	gudmap_developingGonad_e14.5_ epididymis_500
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	SMARCA5 ANKFY1 WDR33 ESR1 REST ECM1 MYSM1 ADD1 ADD3 NRXN3 NRK LRP1 SMARCC1 CAPS2 PCDH9 CDH16 CDK7	2.41e-05	790	143	17	gudmap_developingGonad_e16.5_epididymis_1000
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 HDAC4 ERC1 PIEZO1 HUNK FRY RALBP1 CDH1	2.04e-07	189	145	8	fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Neuronal-INs\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	MAP1B CERS6 TIAM2 CEP170 CRACD NRXN3 PTPRR NSG1	2.69e-07	196	145	8	556e18eae05bf19259fe02848bcc9120aa2a9d29
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1-Excitatory_Neuron.Slc17a7.Reln_(Medial_entorrhinal_cortexm,_Reln+/Cbln1+)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ARHGAP40 SOX30 EQTN ERN2 C12orf50	1.67e-06	61	145	5	5e855b5462f42b7a1d0bbd518cc11072342ce0cc
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1-Excitatory_Neuron.Slc17a7.Reln_(Medial_entorrhinal_cortexm,_Reln+/Cbln1+)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ARHGAP40 SOX30 EQTN ERN2 C12orf50	1.67e-06	61	145	5	2fc13475581431f82e0b5ef42e18cd29c9787666
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 CERS6 CCNA2 ANGPTL2 CDH1 SDC1 RAPGEFL1	2.28e-06	182	145	7	9174fb0b7ed8f721a5c513e41fd80476a9f34332
ToppCell	PND07-28-samps-Epithelial-Alveolar_epithelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	NEXMIF TFCP2L1 FAT2 KLF5 CDH1 SDC1 CDH16	2.36e-06	183	145	7	23e55f88a802a9299d2773f9394970e86e8bbfaa
ToppCell	PND07-28-samps-Epithelial-Alveolar_epithelial-AT2\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	NEXMIF TFCP2L1 FAT2 KLF5 CDH1 SDC1 CDH16	2.36e-06	183	145	7	0a69e22750dd8b66ab988cf36d0dd2b59e2f7d26
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC4 ERC1 PIEZO1 HUNK FRY RALBP1 CDH1	2.54e-06	185	145	7	a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANKRD23 UBTD1 ZNF853 KIF17 IL3RA MADCAM1 IPO11	2.54e-06	185	145	7	a987dbf6adf533c5f8a0a8a465a6c8e67e0ffcc8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 HDAC4 ERC1 HUNK FRY RALBP1 CDH1	2.92e-06	189	145	7	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC4 ERC1 HUNK FRY IQCA1 RALBP1 CDH1	3.24e-06	192	145	7	fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC4 ERC1 HUNK FRY IQCA1 RALBP1 CDH1	3.24e-06	192	145	7	bae236c9f1fac77bce28d0a9cf090100d391ff77
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 CERS6 ERN2 FAT2 KLF5 CDH1 RAPGEFL1	3.36e-06	193	145	7	a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TEK FAM78A UBTD1 KIF17 IL3RA MADCAM1 IPO11	3.36e-06	193	145	7	807fa1443b3c883cb318c71f4fca3c41d58f4910
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 MAP1B ESR1 CERS6 CRACD DST LRP1	3.59e-06	195	145	7	d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TEK KIAA1671 UBTD1 KIF17 IL3RA MADCAM1 IPO11	3.72e-06	196	145	7	9b53e3fdb23dbdfc2e7ce012c6b2ce50700c95d5
ToppCell	COVID-19-Epithelial\|COVID-19 / Condition, Lineage and Cell class	DNALI1 ROPN1L IQCA1 KLF5 VWA3B CDH1 CFAP46	3.84e-06	197	145	7	18fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HIVEP2 MAP1B CERS6 FRY NRXN3 KIAA1549L PTPRR	3.97e-06	198	145	7	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TEK FAM78A UBTD1 KIF17 IL3RA MADCAM1 IPO11	3.97e-06	198	145	7	96d46e73f968391000ecd14c787efb93c79f96ec
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-35\|World / Primary Cells by Cluster	TUT4 MAP1B CERS6 TIAM2 CEP170 NRXN3 NSG1	3.97e-06	198	145	7	de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell	distal-Epithelial-Differentiating_Basal\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ERN2 FAT2 PTPRR KLF5 NSG1 SDC1 RAPGEFL1	4.11e-06	199	145	7	286d52f25120293620bdbfd62b832f08e118adf6
ToppCell	control-Epithelial-Secretory\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ERN2 TFCP2L1 FAT2 KLF5 SDC1 GOLGA4 RAPGEFL1	4.11e-06	199	145	7	3d01f90ffd271ca00129192787e4921bdca7e01e
ToppCell	facs-Aorta-Heart-3m-Endothelial-coronary_vascular_endothelial_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO SOX30 ESX1 TFCP2L1 PTPRR IPO11	4.74e-06	132	145	6	dc13b54e38fbda9341972cef11833041f2f2a345
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIAA1671 FAT2 KLF5 SDC1 NR1D2 RAPGEFL1	1.42e-05	160	145	6	445cef1f2f3279672620664792d4eec54df71bdb
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARHGAP40 HUNK ERN2 NRXN3 PTPRR KLF5	1.47e-05	161	145	6	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	MAP1B CRACD NRXN3 PTPRR NSG1	1.57e-05	96	145	5	56e993d37b7958abe56682422536045550e29b41
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERC1 FAT2 IQCA1 RALBP1 CDH1 CDH16	2.01e-05	170	145	6	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	IIF-Myeloid-pDC\|IIF / Disease, Lineage and Cell Type	RRBP1 GZMB NR5A1 CDH1 KIF17 IL3RA	2.36e-05	175	145	6	35cfb7d0b88678ff5b83ad6e19dbc15a908a3fcc
ToppCell	B_cells-pDCs\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	CERS6 DST GZMB CDH1 MAP2K6 IL3RA	2.44e-05	176	145	6	ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCell	ILEUM-inflamed-(3)_pDC\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	HIVEP1 CERS6 RRBP1 GZMB CDH1 IL3RA	2.44e-05	176	145	6	b9f847dd55703e413f3cd815eef5724fffaf13b3
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TEK UBTD1 KIF17 IL3RA MADCAM1 IPO11	2.60e-05	178	145	6	aa44851653d276226b922ee14dd1fc8d1a844cdf
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CPAMD8 ARHGAP40 ERN2 UBTD1 IQCA1 CDH1	2.60e-05	178	145	6	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	E18.5-samps\|World / Age Group, Lineage, Cell class and subclass	TFCP2L1 SARS2 KLF5 CDH1 SDC1 CUX1	2.94e-05	182	145	6	9649f15858d1ede73e068afc59df3ac367b49687
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RRBP1 GZMB CDH1 MAP2K6 KIF17 IL3RA	2.94e-05	182	145	6	9bbe8062aa562dc3b9c299581faf6ebbcb72a9f7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ERN2 FAT2 PTPRR KLF5 SDC1 RAPGEFL1	2.94e-05	182	145	6	678eadd57e7e830fc2bf9fd35616d3badce01705
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CPAMD8 ARHGAP40 XDH ERN2 PTPRR CDH1	2.94e-05	182	145	6	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ERN2 FAT2 PTPRR KLF5 SDC1 RAPGEFL1	2.94e-05	182	145	6	8d1229fa5aa6e2e38f2ac6fe4f4dc89752fe9344
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-plasmacytoid_dendritic_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RRBP1 GZMB CDH1 MAP2K6 KIF17 IL3RA	2.94e-05	182	145	6	4602a98df7045e2c70b7560abfba9b444fbd5d30
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PUF60 XDH CCNA2 SARS2 NRK UNK	3.04e-05	183	145	6	ba7753e9fe2a6a87c5264f299ac97da2ddbda178
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 ERC1 FRY TFCP2L1 RALBP1 CDH1	3.04e-05	183	145	6	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	(7)_DC_plasmacytoid\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	CERS6 RRBP1 GZMB CDH1 KIF17 IL3RA	3.04e-05	183	145	6	2c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCell	CV-Severe-3\|CV / Virus stimulation, Condition and Cluster	TSC22D2 SEMA4C ZACN GZMB LRP1 MADCAM1	3.13e-05	184	145	6	1c9bda00bb6efd98f68781ca06655bf6c4282f27
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	CPAMD8 ARHGAP40 UBTD1 TFCP2L1 KLF5 PCDH9	3.23e-05	185	145	6	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT2 KLF5 KEL CDH1 SDC1 RAPGEFL1	3.23e-05	185	145	6	e0172e0ab0f1d7151a3c3c63bb7c84d6bda92035
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP1 MAP1B ESR1 TSC22D2 ATF4 MAP2K3	3.23e-05	185	145	6	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TEK UBTD1 KIF17 IL3RA MADCAM1 IPO11	3.33e-05	186	145	6	e9d12f2fcd346fc8d00f7178324ea5997628df8a
ToppCell	E17.5-Epithelial\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NEXMIF KLF5 CDH1 SDC1 CUX1 CDH16	3.43e-05	187	145	6	fdabe716ce67f2eede90548198cbe20bbf693570
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	CPAMD8 ARHGAP40 UBTD1 KLF5 CDH1 PCDH9	3.43e-05	187	145	6	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC4 ERC1 HUNK FRY RALBP1 CDH1	3.43e-05	187	145	6	f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCell	tumor_Lung-Epithelial_cells-tS3\|tumor_Lung / Location, Cell class and cell subclass	MAP1B DNER DNALI1 ROPN1L VWA3B CFAP46	3.53e-05	188	145	6	26326b4e298e33f9ba393fc632238aa8c54b1ea3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC4 ERC1 HUNK FRY RALBP1 CDH1	3.53e-05	188	145	6	e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCell	droplet-Lung-nan-18m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEXMIF TFCP2L1 FAT2 CDH1 SDC1 CDH16	3.64e-05	189	145	6	ca657353f2b649530809c0bc057e448adc511ec1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC4 HUNK FRY RALBP1 KEL CDH1	3.64e-05	189	145	6	8ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC4 ERC1 HUNK FRY RALBP1 CDH1	3.64e-05	189	145	6	bfc76a72b600d641c8fe58346e5d8986c34f3981
ToppCell	droplet-Lung-nan-18m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEXMIF TFCP2L1 FAT2 CDH1 SDC1 CDH16	3.64e-05	189	145	6	e5325f1c7430b574947f8ee67e425455b60dc518
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	UBTD1 NR5A1 KIF17 IL3RA MADCAM1 IPO11	3.64e-05	189	145	6	1d660bceee449aebf12fc9af4c74af246837b27a
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TEK UBTD1 KIF17 IL3RA MADCAM1 IPO11	3.64e-05	189	145	6	b5fa3a619e3b554a1a45a551c9b6369075fe5615
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIAA1671 UBTD1 KIF17 IL3RA MADCAM1 IPO11	3.64e-05	189	145	6	a34f008dfcee4012977bbc5b60de6f0329ca2f65
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TEK UBTD1 KIF17 IL3RA MADCAM1 IPO11	3.75e-05	190	145	6	d4aefae2d3164db6a9e953c54af0151501e9d1da
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	TSC22D2 TIAM2 CRACD NRXN3 DST PTPRR	3.75e-05	190	145	6	842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCell	facs-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NEXMIF TFCP2L1 KLF5 CDH1 SDC1 CDH16	3.86e-05	191	145	6	f98fc372e579ce69409afbbe0f83c03c7ea62632
ToppCell	facs-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NEXMIF TFCP2L1 KLF5 CDH1 SDC1 CDH16	3.86e-05	191	145	6	210589095a3f5d5117174caf6ec110b502f27030
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC4 HUNK KIAA1549L RALBP1 CDH1 PCDH9	3.86e-05	191	145	6	96b78b4e819ea6052334bfcbc7abbf35897df885
ToppCell	facs-Lung-3m-Epithelial-alveolar_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NEXMIF TFCP2L1 KLF5 CDH1 SDC1 CDH16	3.97e-05	192	145	6	4a46f7980ec145be5b4bf8b98265e3e0f2ea4c63
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)\|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MPO ADD3 CRACD PRAM1 KLF5 KEL	3.97e-05	192	145	6	072281344d58e85c9a290750b488d0c101f75d54
ToppCell	droplet-Fat-Scat-18m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP40 TFCP2L1 NRXN3 KLF5 CDH1 RAPGEFL1	3.97e-05	192	145	6	4098b5170c9995718758a082d1b8bcb86d5a289e
ToppCell	droplet-Fat-Scat-18m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP40 TFCP2L1 NRXN3 KLF5 CDH1 RAPGEFL1	3.97e-05	192	145	6	936028fe851e8dd2b906df0210acc574c017b499
ToppCell	droplet-Fat-Scat-18m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP40 TFCP2L1 NRXN3 KLF5 CDH1 RAPGEFL1	3.97e-05	192	145	6	62e55ed0d46b2e7b07dc42399972a099576cbc5f
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	TCOF1 TROAP PIEZO1 RALBP1 CAPRIN2 ATF4	3.97e-05	192	145	6	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	facs-Lung-24m-Epithelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DNALI1 TFCP2L1 IQCA1 KLF5 CDH1 SDC1	3.97e-05	192	145	6	ebfd8209a7353fbccb8ca7ade14b4f25822cebd2
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DNER TFCP2L1 NRK PCDH9 SDC1 CDH16	3.97e-05	192	145	6	32e4a180037e516c5cc798cd9dada9385e0f43ae
ToppCell	ASK452-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	DNALI1 ROPN1L IQCA1 VWA3B CAPS2 CFAP46	4.09e-05	193	145	6	c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	CPAMD8 ARHGAP40 NEXMIF XDH ERN2 NRXN3	4.09e-05	193	145	6	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	facs-Lung-24m-Epithelial-alveolar_epithelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NEXMIF TFCP2L1 KLF5 CDH1 SDC1 CDH16	4.09e-05	193	145	6	4a1b4a2faf741ffba5c84218af4df6a8b2a9f4de
ToppCell	facs-Lung-24m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NEXMIF TFCP2L1 KLF5 CDH1 SDC1 CDH16	4.09e-05	193	145	6	68adc680deb2f1a29d3cca19c13b9f6271dd4d60
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 ERC1 TFCP2L1 RALBP1 CDH1 CDH16	4.09e-05	193	145	6	e7012f7b53971972299db34fa51ff51a4e4987fe
ToppCell	facs-Lung-24m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NEXMIF TFCP2L1 KLF5 CDH1 SDC1 CDH16	4.09e-05	193	145	6	819e6ee2ffa3e31bf9a2d57c99d9e3eac7072765
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DNER ECM1 ANGPTL2 MROH2B NRK LRP1	4.21e-05	194	145	6	e2db75f4de114631b8bda4e188f84446545538b7
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 FRY RALBP1 KLF5 CDH1 CDH16	4.21e-05	194	145	6	4d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCell	ASK452-Epithelial-Ciliated\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	DNALI1 ROPN1L IQCA1 VWA3B CAPS2 CFAP46	4.21e-05	194	145	6	5aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCell	COPD-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	MAP1B CERS6 ADD3 KIAA1671 DST IPO11	4.33e-05	195	145	6	e91ce548ae7224661ee5d2f2639794a5f69798ee
ToppCell	distal-Epithelial-Differentiating_Basal-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ERN2 FAT2 KLF5 NSG1 SDC1 RAPGEFL1	4.33e-05	195	145	6	3fe6e49a9161fc9e5160251e6932cb5378175a54
ToppCell	11.5-Distal-Endothelial\|Distal / Age, Tissue, Lineage and Cell class	TEK KIAA1671 FRY KIF17 IL3RA MADCAM1	4.33e-05	195	145	6	efdede0f476883ffddd247fa7bc6449e7932613e
ToppCell	11.5-Distal-Endothelial-Endothelial\|Distal / Age, Tissue, Lineage and Cell class	TEK KIAA1671 FRY KIF17 IL3RA MADCAM1	4.33e-05	195	145	6	1e9b52b201ab6c78f536609e2afe1d680c71a6e7
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TEK KIAA1671 UBTD1 IL3RA MADCAM1 IPO11	4.33e-05	195	145	6	f65053811074a7f2ff0368f3a63b88e2a08da1a0
ToppCell	PND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NEXMIF TFCP2L1 KLF5 CDH1 SDC1 CUX1	4.33e-05	195	145	6	43164511f32e4591cb5399182fbac0b911716233
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TEK UBTD1 KIF17 IL3RA MADCAM1 IPO11	4.33e-05	195	145	6	ccfb80e3bfdf5304fa798e0a47b473955ecc0c6d
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Club\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP40 XDH ERN2 KLF5 SDC1 RAPGEFL1	4.33e-05	195	145	6	b9e8f405f6d837bb39b615836d3e2df349737c0e
ToppCell	PND01-Epithelial-Epithelial_Alveolar\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NEXMIF TFCP2L1 KLF5 CDH1 SDC1 CUX1	4.33e-05	195	145	6	9337111d75a487abc02969337718c30b1fe81379
ToppCell	wk_20-22-Epithelial-Distal_epithelial-type_II_pneumocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SMARCA5 KLF5 NSG1 CDH1 SDC1 CDH16	4.33e-05	195	145	6	45d1acd316d0ced97dfb150c3a943128d8fa4e7e
ToppCell	wk_15-18-Epithelial-Distal_epithelial-type_II_pneumocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SMARCA5 KLF5 NSG1 CDH1 SDC1 CDH16	4.33e-05	195	145	6	0e3aac1b1a1fd483f5fb9a394eb90c0e1ce63542
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NEXMIF PIEZO1 RALBP1 KLF5 CDH1 CDH16	4.33e-05	195	145	6	3d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCell	NS-moderate-d_16-33-Epithelial-Secretory\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ERN2 TFCP2L1 KLF5 PPM1L CDH1 SDC1	4.45e-05	196	145	6	70384c1da9baed843f414cfd1403ddd586a2db07
ToppCell	distal-Epithelial-Proximal_Basal\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	XDH HUNK ERN2 FAT2 KLF5 NSG1	4.45e-05	196	145	6	c102b28d5d1d90b9f7024cb51114276354be26a5
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	NEXMIF TFCP2L1 DST KLF5 NRK PCDH9	4.45e-05	196	145	6	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TEK KIAA1671 UBTD1 IL3RA MADCAM1 IPO11	4.45e-05	196	145	6	ccf6881c09e570116cf1bcb71112765ea8c28418
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP1B CERS6 FRY NRXN3 KIAA1549L PTPRR	4.45e-05	196	145	6	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Club\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CPAMD8 ARHGAP40 ITIH2 KLF5 CDH1 SDC1	4.45e-05	196	145	6	4e4c632db73b1340d80bf40a7657cb4821084d3c
ToppCell	wk_20-22-Epithelial-Distal_epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SMARCA5 KLF5 NSG1 CDH1 SDC1 CDH16	4.45e-05	196	145	6	cd507ee2baf4f52d6498811b3510d3164b56311f
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	XDH ERN2 TFCP2L1 KLF5 SDC1 RAPGEFL1	4.45e-05	196	145	6	5789b5b0763d6eab21bf4da1fd8eae6116f46f3f
Drug	deoxybenzoin	ESR1 GZMB CDH1	2.51e-06	5	145	3	CID000009948
Disease	Bladder Neoplasm	MPO ANKFY1 HDAC4 ESR1 KLF5 CDH1	6.42e-05	140	143	6	C0005695
Disease	Malignant neoplasm of urinary bladder	MPO ANKFY1 HDAC4 ESR1 KLF5 CDH1	6.68e-05	141	143	6	C0005684
Disease	spastic quadriplegic cerebral palsy 3 (implicated_via_orthology)	ADD1 ADD3	6.97e-05	3	143	2	DOID:0081361 (implicated_via_orthology)
Disease	Schizophrenia	HDAC4 CYP3A4 ESR1 REST CHRNA4 CCNA2 ARHGAP1 NRXN3 KLF5 LRP1 ATF4 KIF17 IL3RA RAI1	1.04e-04	883	143	14	C0036341
Disease	interleukin 10 measurement, mastiha supplement exposure measurement	ESR1 GZMB	1.39e-04	4	143	2	EFO_0004750, EFO_0600067
Disease	restrictive cardiomyopathy (is_implicated_in)	MAP2K3 MAP2K6	3.45e-04	6	143	2	DOID:397 (is_implicated_in)
Disease	Intellectual Disability	HIVEP2 HDAC4 MAP1B PUF60 QRICH1 CCNA2 FRY MAN1B1 RAI1	3.46e-04	447	143	9	C3714756
Disease	diastolic blood pressure, systolic blood pressure	ANKFY1 HDAC4 MAP1B ESR1 ADD1 KIAA1671 SEC16A LRP1 VWA3B CLEC16A CUX1	4.40e-04	670	143	11	EFO_0006335, EFO_0006336
Disease	Hypoxemia	MPO ESD ATF4	5.47e-04	33	143	3	C0700292
Disease	Hypoxia	MPO ESD ATF4	5.47e-04	33	143	3	C0242184
Disease	Anoxemia	MPO ESD ATF4	5.47e-04	33	143	3	C0003129
Disease	Anoxia	MPO ESD ATF4	5.47e-04	33	143	3	C0003130
Disease	Profound Mental Retardation	HDAC4 CCNA2 FRY MAN1B1 RAI1	5.95e-04	139	143	5	C0020796
Disease	Mental Retardation, Psychosocial	HDAC4 CCNA2 FRY MAN1B1 RAI1	5.95e-04	139	143	5	C0025363
Disease	Mental deficiency	HDAC4 CCNA2 FRY MAN1B1 RAI1	5.95e-04	139	143	5	C0917816
Disease	Autism Spectrum Disorders	NRXN3 USH2A PCDH9 RAI1	7.90e-04	85	143	4	C1510586
Disease	Acute Confusional Migraine	ESR1 LRP1	8.21e-04	9	143	2	C0521664
Disease	Status Migrainosus	ESR1 LRP1	8.21e-04	9	143	2	C0338489
Disease	Abdominal Migraine	ESR1 LRP1	8.21e-04	9	143	2	C0270858
Disease	Sick Headaches	ESR1 LRP1	8.21e-04	9	143	2	C0700438
Disease	Cervical Migraine Syndrome	ESR1 LRP1	8.21e-04	9	143	2	C0007852
Disease	Hemicrania migraine	ESR1 LRP1	8.21e-04	9	143	2	C0018984
Disease	urate measurement, bone density	ERC1 DNER QRICH1 TIAM2 CCER1 SCYL2 SEC16A VWA3B CAPS2 USH2A	9.06e-04	619	143	10	EFO_0003923, EFO_0004531
Disease	FEV/FEC ratio	HIVEP2 HDAC4 WDR33 ERC1 SOX30 DNER CERS6 REST RRBP1 ADD3 DST LRP1 CLEC16A CUX1 RAPGEFL1	9.40e-04	1228	143	15	EFO_0004713
Disease	cerebral palsy (implicated_via_orthology)	ADD1 ADD3	1.02e-03	10	143	2	DOID:1969 (implicated_via_orthology)
Disease	Mesothelioma	PUF60 ESR1 CDH1	1.04e-03	41	143	3	C0025500
Disease	serum IgG glycosylation measurement	HIVEP2 DNER HUNK TSC22D2 SKI TEK FRY PTPRR USH2A	1.06e-03	523	143	9	EFO_0005193
Disease	Major Depressive Disorder	MPO XDH REST PTPRR LRP1 CUX1	1.23e-03	243	143	6	C1269683
Disease	Prostatic Intraepithelial Neoplasias	ESR1 CDH1	1.25e-03	11	143	2	C0282612
Disease	Mammary Ductal Carcinoma	ATF4 CDH1	1.25e-03	11	143	2	C0021367
Disease	Invasive Ductal Breast Carcinoma	ATF4 CDH1	1.25e-03	11	143	2	C1134719
Disease	tuberculin skin test reactivity measurement, decreased susceptibility to bacterial infection	ESR1 FRY	1.49e-03	12	143	2	EFO_0008307, EFO_0008322
Disease	methionine sulfone measurement	CYP3A4 CYP3A43	1.49e-03	12	143	2	EFO_0800072
Disease	outer ear morphology trait	HIVEP2 CUX1	1.49e-03	12	143	2	EFO_0007664
Disease	triacylglycerol 58:12 measurement	DNER NRXN3	1.49e-03	12	143	2	EFO_0010439
Disease	pulmonary function measurement, smoking behaviour measurement, FEV/FEC ratio	HDAC4 DNER LRP1	1.55e-03	47	143	3	EFO_0003892, EFO_0004713, EFO_0005671
Disease	HbA1c measurement	CPAMD8 PIEZO1 SOX30 CERS6 NUDCD3 ZKSCAN5 SEC16A KEL CDH1 RAI1	1.72e-03	675	143	10	EFO_0004541
Disease	juvenile polyposis syndrome (implicated_via_orthology)	HIVEP1 HIVEP2	1.76e-03	13	143	2	DOID:0050787 (implicated_via_orthology)
Disease	Migraine Disorders	ESR1 LRP1	1.76e-03	13	143	2	C0149931
Disease	systolic blood pressure, cigarettes per day measurement	FRY NRXN3	1.76e-03	13	143	2	EFO_0006335, EFO_0006525
Disease	X-21410 measurement	CYP3A4 ZKSCAN5	2.68e-03	16	143	2	EFO_0800813
Disease	Alzheimer's disease (implicated_via_orthology)	HIVEP1 HIVEP2 LRP1	2.69e-03	57	143	3	DOID:10652 (implicated_via_orthology)
Disease	age at first birth measurement	VWC2 ESR1 SMARCC1 PCDH9	2.81e-03	120	143	4	EFO_0009101
Disease	noggin measurement	HIVEP2 SKI	3.39e-03	18	143	2	EFO_0021995
Disease	Ulcerative Colitis	MPO ECM1 CDH1	3.58e-03	63	143	3	C0009324
Disease	pulmonary hypertension (is_marker_for)	HDAC4 ESR1 TEK	3.74e-03	64	143	3	DOID:6432 (is_marker_for)
Disease	metabolonic lactone sulfate measurement	CYP3A4 CYP3A43	3.78e-03	19	143	2	EFO_0800659
Disease	etiocholanolone glucuronide measurement	CYP3A4 XDH	3.78e-03	19	143	2	EFO_0800362
Disease	dehydroepiandrosterone sulphate measurement	CYP3A4 CYP3A43 ZKSCAN5	4.44e-03	68	143	3	EFO_0007001
Disease	Malignant neoplasm of ovary	DPH1 ESR1 NR5A1 CDH1	4.52e-03	137	143	4	C1140680
Disease	BREAST CANCER	ESR1 CDH1	4.61e-03	21	143	2	114480
Disease	cardiovascular system disease (is_implicated_in)	MPO XDH	4.61e-03	21	143	2	DOID:1287 (is_implicated_in)
Disease	Ovarian Failure, Premature	EIF4ENIF1 NR5A1	4.61e-03	21	143	2	C0085215

Protein segments in the cluster

Peptide	Gene	Start	Entry
QQELTPLPLLKDVPA	PPP2R5B	56	Q15173
PNIPIELIPHINKQT	CEP170	846	Q5SW79
EELPQLINANFPVDP	ESD	126	P10768
PPLLELKQEQEEPPQ	ESX1	101	Q8N693
SDQLPPQQPLEAEKA	CHRNA4	426	P43681
EPLVKPQSQAQVEPV	ANKRD23	96	Q86SG2
LDQNIIPENLPAPTD	CAPS2	116	Q9BXY5
TPIKIEDPNQFVPLN	ADD3	481	Q9UEY8
PQSQLLAGIVVDKPP	ADD3	521	Q9UEY8
PVPALDLGQQLQLKV	CUX1	91	P39880
DLFAPLVQETNKQPP	ATF4	121	P18848
PFLDNILEPPVKTQN	DEPDC4	251	Q8N2C3
EQEPTQQFIPVKRPI	GZMB	81	P10144
LNEQTLPVQPGEIKP	CFAP46	1561	Q8IYW2
EIQSDQNLKVLPPPL	ANGPTL2	241	Q9UKU9
QIPPEILKNPQLQAA	DPH1	36	Q9BZG8
CTFLNPEQIIPKVPQ	CCER1	381	Q8TC90
QDLKLAPQQLDIPIP	IQCA1	106	Q86XH1
KNNVLIVCVPNPPID	NUP50	421	Q9UKX7
RQQQVLPLDPAEPEI	RAI1	1561	Q7Z5J4
KPIQEPEVPQIDVPN	RALBP1	171	Q15311
NHKPSPDQIIQPLLE	ERC1	1001	Q8IUD2
QTENPENPLRCPIKL	QRICH1	691	Q2TAL8
KPPNQPLAAIDSENV	RABGEF1	461	Q9UJ41
ALQRQPPSPKQLEEE	PTPN7	86	P35236
QLQSAPLPIVDKGPV	INTS15	31	Q96N11
NPNLQTEEALPLPKE	ANKFY1	516	Q9P2R3
VVQEGPAQKELLPPV	REST	656	Q13127
ELLQRAPLQQPDPAQ	FAM201A	101	Q5SY85
ELDPLPEKVLQQRPN	HDAC4	996	P56524
LLGQSLQVKPLQVEP	MADCAM1	16	Q13477
VVFLNVPENLKNPEP	MAP1B	356	P46821
APQEKERPLQQVSPV	KIAA1671	1476	Q9BY89
PDNLDPIPKNILFVI	ITIH2	301	P19823
PILPRIQEQFQKNPD	NUDCD3	166	Q8IVD9
NVDVLKPLPQLEPQA	GOLGA4	241	Q13439
VPPPNKEAVDLANRI	DST	941	Q03001
KNEPVDRPPVLLIAN	LRP1	191	Q07954
PQVVEKQQETPLAPA	ERN2	456	Q76MJ5
VVENALKVNPILGPQ	IPO11	751	Q9UI26
LQEEIDAVLPNKAPP	CYP3A4	331	P08684
NELEPLNRPQLKIPL	ESR1	21	P03372
LEKPLQVRPQAPLEL	FAT2	3171	Q9NYQ8
REELPENVPIGNIPK	PCDH9	31	Q9HC56
IPPNDPRIKNQADCI	MPO	296	P05164
LDVNQLQFPPPDKVV	NSG1	31	P42857
LLQADPVVKNPPNNL	KIAA1549L	1166	Q6ZVL6
LNPDVPEALQAPAQV	PARP4	1061	Q9UKK3
INNVQDPQKPEPRDK	MAN1B1	641	Q9UKM7
QPEQAPKVLNVVVDP	PTPRR	291	Q15256
PNPVLLKQPEESNLN	PAPOLG	281	Q9BWT3
LLQTKEDPNPPITNL	IL3RA	16	P26951
KHEPLQLIQPQFETP	IFT52	316	Q9Y366
TQIPLKLDNLPILQP	CYP3A43	471	Q9HB55
EIQVLKEPLQQPTFP	EIF2AK1	46	Q9BQI3
QLPRPNCPVETLKEQ	CDK7	306	P50613
LLKQEGPVEAAQPPV	CRACD	491	Q6ZU35
NVPDPVAKPAFQLLV	CPAMD8	1496	Q8IZJ3
PLQPQVQFLDKPILN	GLB1L	611	Q6UWU2
LEPDPVKRPNIQQAL	HUNK	301	P57058
ANGPQIAPPNAILEK	CERS6	71	Q6ZMG9
KNEPIHLDVVEQPPQ	BTBD7	1021	Q9P203
VFNVNAPLPPRKEQE	CAPRIN2	766	Q6IMN6
PTKQAEEILNAILPP	DNALI1	61	O14645
LPQEAVPLQKELPSL	ECM1	106	Q16610
VPLQKELPSLQHPNE	ECM1	111	Q16610
LEKGLPSVQQPLLQV	FRY	2231	Q5TBA9
TKQDVPQQLQPAEPI	CCDC168	1861	Q8NDH2
ENINPEKAAPVQQPR	CCNA2	31	P20248
KPTIEALPNVLPLNE	EQTN	21	Q9NQ60
RQLQPVPATQEPDKI	DNER	151	Q8NFT8
NDRIVPQPPLQKLSA	SEC24B	1136	O95487
PEPQPTREKQLQELQ	NOA1	81	Q8NC60
VSVPQALPKAQPAEL	CDH16	11	O75309
NPKPQVINIIDADLP	CDH1	606	P12830
LPQEEPQEVPLQGLL	KIF17	596	Q9P2E2
QQLKQVVEEPSPQLP	MAP2K3	276	P46734
QLKQVVEEPSPQLPA	MAP2K6	266	P52564
LELNLPSEPQPKQQA	MROH5	916	Q6ZUA9
LPAQEQLRPKPQLEQ	NR1D2	221	Q14995
VTLPKNPLEIIIPQN	NRK	1446	Q7Z2Y5
QALKLPNQTHPDVPV	SARS2	166	Q9NP81
EPPKLQARGPQEILV	USH2A	4536	O75445
AAPVVPQALIDQLKP	PCMT1	161	P22061
PNVPELILQLLQLEP	NR5A1	221	Q13285
NPLIPLFQQPLVQEI	TBC1D22B	276	Q9NU19
LPPLTPEQQEALQKA	PUF60	56	Q9UHX1
VKPPVADSLANPLQL	TSC22D2	616	O75157
SAQVIKPPLIFVDPN	TCOF1	951	Q13428
AQDQPKILSKNEPIP	FAM78A	236	Q5JUQ0
LEAAAPIQPTPVAQK	NEXMIF	41	Q5QGS0
NNRDLKPQPDIVLLP	NRXN3	496	Q9HDB5
DPALRKEKDPQPQQL	PRAM1	541	Q96QH2
LQHLQEKNPEQEPIP	ARHGAP1	246	Q07960
PLKNLNVVIPDPDIL	PPM1L	271	Q5SGD2
APQNPPQRKKVSLLE	SETD5	1056	Q9C0A6
PELGPVFKQQEPIQI	SCYL2	411	Q6P3W7
LPQIVATNLPPEDQD	SDC1	21	P18827
DLQQKLEEVRQPPPR	WIZ	1556	O95785
KLQQRQPLPDSNPEE	SEMA4C	816	Q9C0C4
LPIFKQEEPQLSPEN	TFCP2L1	26	Q9NZI6
LQQICRAPEPPVKEN	MROH2B	281	Q7Z745
PVPNIEEVVLPKNVN	SMARCC1	376	Q92922
APNVALAPPAQQKVV	SKI	416	P12755
LQVKPEQVLLLPQPQ	SOX30	71	O94993
EIPGQPVPKNILQEL	EIF4ENIF1	516	Q9NRA8
PVPKNILQELLGQPV	EIF4ENIF1	521	Q9NRA8
PNLFVPLNTNPKEVQ	ADD1	486	P35611
IPLQSQSQEPLKPQE	C12orf50	56	Q8NA57
PEKLERIQLPVPNAA	CLEC16A	516	Q2KHT3
AVNLQVAKLNPPPEA	SCGB1D4	41	Q6XE38
IPLEKLAQAPEQPGQ	VWC2	31	Q2TAL6
PLAPVQPQANGKEEE	TTBK1	721	Q5TCY1
PNHLNAEVAPQPLKE	ZSCAN20	186	P17040
LPAFAVVPNIPNLKQ	ARHGAP40	366	Q5TG30
PPAEQDPVQLKTQLE	RRBP1	1281	Q9P2E9
KSLLPPPNQSQLLEE	TIAM2	996	Q8IVF5
IKVIPNLPSEGQPAL	SEC16A	1461	O15027
QQIHIPPELPDILKQ	ROPN1L	11	Q96C74
VQKPPLNIQRPLVDS	TROAP	51	Q12815
QKDPPADVQLFQEVP	XDH	551	P47989
DILPPQPENIKISNI	TEK	636	Q02763
KDFVIQVIINQPPPP	UBTD1	211	Q9HAC8
PETPIQNPVVKHLLQ	PPP6R1	421	Q9UPN7
DLKTQVPPQQLVPCF	ZACN	206	Q401N2
PVQPELQLELVPAAG	ZNF853	406	P0CG23
LIPQDPPEQELILVK	ZNF397	11	Q8NF99
IPQKQEILVEPEPLF	UBXN7	81	O94888
PEANPVKQLQPNEEA	PIEZO1	2366	Q92508
LAQIQRLVAEPPKPD	VWA3B	351	Q502W6
NKVPIPAPNEVLNDR	WDR33	511	Q9C0J8
QILEDTHKVQPQPPA	ZSWIM1	366	Q9BR11
KLPPQIPHLELGNDQ	ZFAND4	336	Q86XD8
PRNPELPNAAQAQKE	SMARCA5	801	O60264
ELKIPEENQPPSKQV	RAPGEFL1	276	Q9UHV5
VLPPLQQEDPGKQVA	HIVEP2	1126	P31629
FLQQRKPPVIPVLQE	TUT4	1131	Q5TAX3
PPAATAQVLQAQPEK	UNK	16	Q9C0B0
LQKVPAKDPQQEPDA	ZFYVE26	466	Q68DK2
QPPIERKVIELPNIQ	USP11	176	P51784
VQRENAKKVLNPPAP	HIVEP1	2606	P15822
PEQAPQKPRLLEENA	ZKSCAN5	171	Q9Y2L8
VIELKPEPDAQPQQA	ZNF296	31	Q8WUU4
PNLKQEEGEKVLPPQ	TRERF1	541	Q96PN7
PVIQIDQPEFDVPLK	KEL	221	P23276
PEVNNIFIKQELPTP	KLF5	201	Q13887
PQGPPKVVVRNELLD	LRFN2	596	Q9ULH4
RQLPSPEPCEIQKNL	MYSM1	336	Q5VVJ2