Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F2 CYP4F12

2.13e-045932GO:0052871
GeneOntologyMolecularFunction4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity

FUT5 FUT6

3.18e-046932GO:0017083
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F2 CYP4F12

4.44e-047932GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F2 CYP4F12

4.44e-047932GO:0018685
GeneOntologyMolecularFunctionaromatase activity

CYP1A2 CYP4F2 CYP4F12

5.75e-0435933GO:0070330
GeneOntologyMolecularFunctionalpha-(1->3)-fucosyltransferase activity

FUT5 FUT6

5.90e-048932GO:0046920
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

TSPOAP1 RIMBP2

7.56e-049932GO:0099511
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

TSPOAP1 RIMBP2

7.56e-049932GO:0099626
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F2 CYP4F12

9.42e-0410932GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F2 CYP4F12

9.42e-0410932GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F2 CYP4F12

9.42e-0410932GO:0102033
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

TSPOAP1 RYR1 RIMBP2

1.28e-0346933GO:0005245
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP1A2 CYP4F2 CYP4F12

1.54e-0349933GO:0016712
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F12

1.62e-0313932GO:0016713
GeneOntologyBiologicalProcessomega-hydroxylase P450 pathway

CYP1A2 CYP4F2 CYP4F12

3.02e-0514923GO:0097267
GeneOntologyBiologicalProcessmenaquinone catabolic process

CYP4F2 CYP4F12

5.89e-053922GO:0042361
GeneOntologyBiologicalProcessmenaquinone metabolic process

CYP4F2 CYP4F12

1.17e-044922GO:0009233
GeneOntologyBiologicalProcessphylloquinone metabolic process

CYP4F2 CYP4F12

1.17e-044922GO:0042374
GeneOntologyBiologicalProcessphylloquinone catabolic process

CYP4F2 CYP4F12

1.17e-044922GO:0042376
GeneOntologyBiologicalProcessvitamin K catabolic process

CYP4F2 CYP4F12

1.17e-044922GO:0042377
GeneOntologyBiologicalProcessepoxygenase P450 pathway

CYP1A2 CYP4F2 CYP4F12

1.24e-0422923GO:0019373
DomainPLAC

PAPLN ADAMTS10 ADAMTS18 ADAMTSL4

4.86e-0714904PF08686
DomainPLAC

PAPLN ADAMTS10 ADAMTS18 ADAMTSL4

1.85e-0619904PS50900
DomainPLAC

PAPLN ADAMTS10 ADAMTS18 ADAMTSL4

1.85e-0619904IPR010909
DomainADAM_spacer1

PAPLN ADAMTS10 ADAMTS18 ADAMTSL4

4.16e-0623904IPR010294
DomainADAM_spacer1

PAPLN ADAMTS10 ADAMTS18 ADAMTSL4

4.16e-0623904PF05986
DomainTSP_1

PAPLN ADAMTS10 SEMA5B ADAMTS18 ADAMTSL4

1.31e-0563905PF00090
DomainTSP1

PAPLN ADAMTS10 SEMA5B ADAMTS18 ADAMTSL4

1.53e-0565905SM00209
DomainTSP1_rpt

PAPLN ADAMTS10 SEMA5B ADAMTS18 ADAMTSL4

1.53e-0565905IPR000884
DomainTSP1

PAPLN ADAMTS10 SEMA5B ADAMTS18 ADAMTSL4

1.53e-0565905PS50092
DomainPOU

POU5F2 POU2F2 POU5F1

5.79e-0516903SM00352
DomainPOU_2

POU5F2 POU2F2 POU5F1

5.79e-0516903PS00465
DomainPOU_dom

POU5F2 POU2F2 POU5F1

5.79e-0516903IPR000327
DomainPOU_3

POU5F2 POU2F2 POU5F1

5.79e-0516903PS51179
DomainPou

POU5F2 POU2F2 POU5F1

5.79e-0516903PF00157
DomainPOU_1

POU5F2 POU2F2 POU5F1

5.79e-0516903PS00035
DomainPOU_dom_5

POU5F2 POU5F1

6.87e-053902IPR015585
DomainPOU

POU5F2 POU2F2 POU5F1

7.01e-0517903IPR013847
DomainPeptidase_M12B_ADAM-TS

PAPLN ADAMTS10 ADAMTS18

2.04e-0424903IPR013273
Domain-

POU5F2 POU2F2 POU5F1

2.91e-04279031.10.260.40
DomainLambda_DNA-bd_dom

POU5F2 POU2F2 POU5F1

3.61e-0429903IPR010982
DomainGlyco_transf_10

FUT5 FUT6

6.31e-048902PF00852
DomainGlyco_tran_10_N

FUT5 FUT6

6.31e-048902PF17039
DomainGlyco_trans_10

FUT5 FUT6

6.31e-048902IPR001503
DomainGlyco_tran_10_N

FUT5 FUT6

6.31e-048902IPR031481
DomainCyt_P450_E_grp-I

CYP1A2 CYP4F2 CYP4F12

1.33e-0345903IPR002401
DomainCyt_P450_CS

CYP1A2 CYP4F2 CYP4F12

2.13e-0353903IPR017972
DomainCYTOCHROME_P450

CYP1A2 CYP4F2 CYP4F12

2.62e-0357903PS00086
Domain-

CYP1A2 CYP4F2 CYP4F12

2.76e-03589031.10.630.10
Domainp450

CYP1A2 CYP4F2 CYP4F12

2.76e-0358903PF00067
DomainAMP-bd_C

ACSM5 SLC27A5

2.98e-0317902IPR025110
DomainAMP-binding_C

ACSM5 SLC27A5

2.98e-0317902PF13193
DomainCyt_P450

CYP1A2 CYP4F2 CYP4F12

3.04e-0360903IPR001128
PathwayREACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE

CYP1A2 CYP4F2 CYP4F12

1.43e-0511643MM14863
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS10 SEMA5B ADAMTS18 ADAMTSL4

2.82e-0539644M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS10 SEMA5B ADAMTS18 ADAMTSL4

2.82e-0539644MM15165
PathwayKEGG_MEDICUS_REFERENCE_LEWIS_X_ANTIGEN_BIOSYNTHESIS

FUT5 FUT6

2.01e-045642M47966
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS10 SEMA5B ADAMTS18 ADAMTSL4

2.53e-0468644M27303
PathwayKEGG_MEDICUS_REFERENCE_SIALYL_LEWIS_X_ANTIGEN_BIOSYNTHESIS

FUT5 FUT6

3.01e-046642M47967
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

PAPLN POU5F1 ADAMTS10 SEMA5B ADAMTS18 ADAMTSL4

8.33e-0875100620637190
Pubmed

Expression of CYP4F2 in human liver and kidney: assessment using targeted peptide antibodies.

CYP4F2 CYP4F12

8.18e-062100218662666
Pubmed

Involvement of the organic cation transporters in histamine uptake into human vascular endothelial cells.

POU2F2 POU5F1

8.18e-062100219271143
Pubmed

Cloning and characterization of PRAX-1. A new protein that specifically interacts with the peripheral benzodiazepine receptor.

TSPOAP1 TSPO

8.18e-06210029915832
Pubmed

Site-specific fucosylation of sialylated polylactosamines by alpha1,3/4-fucosyltransferases-V and -VI Is defined by amino acids near the N terminus of the catalytic domain.

FUT5 FUT6

8.18e-062100217604274
Pubmed

Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes.

FUT5 FUT6

8.18e-06210021339443
Pubmed

RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses.

TSPOAP1 RIMBP2

8.18e-062100227671655
Pubmed

Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms.

FUT5 FUT6

2.45e-05310027650030
Pubmed

Overexpressed N-fucosylation on the cell surface driven by FUT3, 5, and 6 promotes cell motilities in metastatic pancreatic cancer cell lines.

FUT5 FUT6

2.45e-053100230808544
Pubmed

Sperm 1: a POU-domain gene transiently expressed immediately before meiosis I in the male germ cell.

POU5F2 POU2F2

2.45e-05310027902581
Pubmed

Physical maps of human alpha (1,3)fucosyltransferase genes FUT3-FUT6 on chromosomes 19p13.3 and 11q21.

FUT5 FUT6

2.45e-05310027782074
Pubmed

A human POU domain gene, mPOU, is expressed in developing brain and specific adult tissues.

POU5F2 POU5F1

2.45e-05310027908264
Pubmed

RIM-binding proteins recruit BK-channels to presynaptic release sites adjacent to voltage-gated Ca2+-channels.

TSPOAP1 RIMBP2

2.45e-053100229967030
Pubmed

Efficient stimulus-secretion coupling at ribbon synapses requires RIM-binding protein tethering of L-type Ca2+ channels.

TSPOAP1 RIMBP2

4.89e-054100228874522
Pubmed

miR-125a-3p/FUT5-FUT6 axis mediates colorectal cancer cell proliferation, migration, invasion and pathological angiogenesis via PI3K-Akt pathway.

FUT5 FUT6

4.89e-054100228771224
Pubmed

Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.

CYP4F2 CYP4F12

4.89e-054100222665481
Pubmed

RIM-BPs Mediate Tight Coupling of Action Potentials to Ca(2+)-Triggered Neurotransmitter Release.

TSPOAP1 RIMBP2

4.89e-054100226402606
Pubmed

Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

CYP4F2 CYP4F12

4.89e-054100211185557
Pubmed

Activation of host antiviral RNA-sensing factors necessary for herpes simplex virus type 1-activated transcription of host cell fucosyltransferase genes FUT3, FUT5, and FUT6 and subsequent expression of sLe(x) in virus-infected cells.

FUT5 FUT6

4.89e-054100219349624
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F2 CYP4F12

4.89e-054100218065749
Pubmed

The cyclin-dependent kinase-activating kinase (CAK) assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors.

POU2F2 POU5F1

4.89e-05410029368058
Pubmed

Biallelic variants in TSPOAP1, encoding the active-zone protein RIMBP1, cause autosomal recessive dystonia.

TSPOAP1 RIMBP2

8.14e-055100233539324
Pubmed

Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.

CYP4F2 CYP4F12

8.14e-055100222969154
Pubmed

Interactions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families.

ADAMTS10 ADAMTSL4

8.14e-055100229758265
Pubmed

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.

CYP4F2 CYP4F12

8.14e-055100221466787
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

TSPOAP1 RIMBP2

8.14e-055100217855024
Pubmed

Distinct human α(1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells.

FUT5 FUT6

8.14e-055100229593094
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

PAPLN EMILIN1 C6orf15 ADAMTSL4

8.19e-0579100418757743
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F2 CYP4F12

1.22e-04610029068972
Pubmed

How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs.

TSPOAP1 RIMBP2

1.22e-046100227537484
Pubmed

Cell cycle adaptations of embryonic stem cells.

POU5F1 CDC20

1.70e-047100222084091
Pubmed

Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice.

CYP4F2 CYP4F12

1.70e-047100222160543
Pubmed

OCT-4: a novel estrogen receptor-α collaborator that promotes tamoxifen resistance in breast cancer cells.

POU2F2 POU5F1

2.27e-048100227065334
Pubmed

The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin.

POU2F2 POU5F1

2.27e-048100219536068
Pubmed

Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues.

CYP1A2 CYP4F2 CYP4F12

2.80e-0444100312745259
Pubmed

The END network couples spindle pole assembly to inhibition of the anaphase-promoting complex/cyclosome in early mitosis.

EMILIN1 CDC20

2.91e-049100217609108
Pubmed

Origin of climbing fiber neurons and their developmental dependence on Ptf1a.

POU5F1 GLS

2.91e-049100217928434
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

CXorf38 ABHD10 NLRX1 TRMT2B PGAM5 GLS TSPO ACSM5 AURKAIP1 OVCA2 CARS2

4.29e-0411361001134800366
Pubmed

Molecular and functional architecture of striatal dopamine release sites.

TSPOAP1 RIMBP2

4.43e-0411100234767769
Pubmed

APEX Fingerprinting Reveals the Subcellular Localization of Proteins of Interest.

TRMT2B AURKAIP1

5.30e-0412100227184847
Pubmed

The expression and function of fatty acid transport protein-2 and -4 in the murine placenta.

PLIN5 SLC27A5

5.30e-0412100222028793
Pubmed

Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway.

CA9 POU5F1

5.30e-0412100217418408
Pubmed

Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.

ADAMTS10 ADAMTS18

5.30e-0412100225770910
Pubmed

Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China.

FAM83E FUT6

6.25e-0413100224941225
Pubmed

Ligand-activated peroxisome proliferator activated receptor gamma alters placental morphology and placental fatty acid uptake in mice.

PLIN5 SLC27A5

7.28e-0414100217463056
Pubmed

A novel isoform of Vinexin, Vinexin gamma, regulates Sox9 gene expression through activation of MAPK cascade in mouse fetal gonad.

POU5F1 SORBS3

7.28e-0414100215836771
Pubmed

Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism.

FUT5 FUT6

8.39e-0415100211698403
Pubmed

The REV7 subunit of DNA polymerase ζ is essential for primordial germ cell maintenance in the mouse.

POU5F1 CDC20

9.57e-0416100223463509
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

APBB1 PGAM5 KHSRP CEP170 YLPM1 GIGYF2 SCRIB

1.06e-03549100738280479
Pubmed

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.

CYP1A2 CYP4F2 CYP4F12

1.10e-0370100315128046
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TSPOAP1 PPRC1 USP19 GIGYF2 RIMBP2 SCRIB

1.17e-03407100612693553
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

JCAD KHSRP CEP170 GIGYF2 SCRIB

1.20e-03274100534244482
Pubmed

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

CA9 KHSRP TYK2 TSPO CYP4F12

1.24e-03276100528319085
Pubmed

Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers.

RYR1 TYK2

1.36e-031910028432525
Pubmed

High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.

POU5F1 PRR3 C6orf15 NFKBIL1

1.67e-03175100419851445
Pubmed

Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size.

SAV1 CDC20

1.82e-0322100221512031
Pubmed

USP39 is essential for mammalian epithelial morphogenesis through upregulation of planar cell polarity components.

POU5F1 SCRIB

1.82e-0322100235440748
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

JCAD SAV1 PGAM5 CDC42EP1 CEP170 GIGYF2

1.86e-03446100624255178
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

SOST PAPLN SEZ6L2 SEMA5B CLEC14A C6orf15 CYP4F12 ADAMTSL4 C16orf54

2.16e-03985100912975309
Pubmed

Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis.

POU5F1 SCRIB

2.17e-0324100222333836
Pubmed

CPEB2-eEF2 interaction impedes HIF-1α RNA translation.

ERI3 SORBS3

2.17e-0324100222157746
Pubmed

Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.

POU5F1 C6orf15

2.17e-0324100221323541
Pubmed

A mouse knockout library for secreted and transmembrane proteins.

CA9 SOST PAPLN SEZ6L2 CLEC14A C6orf15

2.17e-03460100620562862
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

KHSRP YLPM1 GIGYF2 SCRIB

2.80e-03202100424639526
CytobandEnsembl 112 genes in cytogenetic band chr19q13

FAM83E TPRX2 POU2F2 RYR1 ZNF71 FCGBP FCGRT NTN5 EPN1 SLC27A5

2.81e-04119210010chr19q13
CytobandEnsembl 112 genes in cytogenetic band chr19p13

CYP4F2 KHSRP TYK2 ADAMTS10 PLIN5 CYP4F12 FUT5 FUT6

3.64e-047971008chr19p13
Cytoband1p36.33

FAAP20 HES4 AURKAIP1

6.53e-047710031p36.33
Cytoband7q36

BLACE KRBA1

1.59e-032710027q36
Cytoband19p13.3

KHSRP PLIN5 FUT5 FUT6

1.84e-03237100419p13.3
GeneFamilyPOU class homeoboxes and pseudogenes

POU5F2 POU2F2 POU5F1

5.87e-0523603523
GeneFamilyADAMTS like

PAPLN ADAMTSL4

2.25e-047602947
GeneFamilyFucosyltransferases|Blood group antigens

FUT5 FUT6

8.25e-0413602434
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS10 ADAMTS18

1.79e-031960250
GeneFamilyAcyl-CoA synthetase family

ACSM5 SLC27A5

3.34e-032660240
GeneFamilyCytochrome P450 family 4

CYP4F2 CYP4F12

6.35e-03366021003
ToppCellBLOOD--(3)_Non_classical_monocytes| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

POU2F2 IER5 ZDHHC1 FCGRT NFKBIL1 HES4 NINJ1

2.84e-07196997b5ce99e27c9e87be52c10c022a665bf4df0e8b05
ToppCellCOVID-19-COVID-19_Severe-Myeloid-CD16+_Monocyte|COVID-19_Severe / Disease, condition lineage and cell class

METRNL POU2F2 IER5 ZDHHC1 FCGRT HES4 NINJ1

3.25e-0720099758fbb7fc7159cbc417e6b457d60b7beba9b90da6
ToppCellVE-CD8-exh_CD4|VE / Condition, Cell_class and T cell subcluster

POU5F1 DOK2 ERI3 OVCA2 DNAH10OS SLC16A7

5.57e-071349964413fec495907184b6d5cf4bda39359506b2c172
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POU2F2 DOK2 RYR1 C11orf21 TMEM102 C16orf54

3.21e-06181996090e89b506d945e123e647d08947e9649a65ce7c
ToppCellmetastatic_Brain-Myeloid_cells-Alveolar_Mac|metastatic_Brain / Location, Cell class and cell subclass

DOK2 FCGRT ASGR1 TSPO DLEU7 ADAMTSL4

3.75e-061869969270e04c61b743874424a5935537b62e7d89c461
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POU2F2 IER5 DOK2 RYR1 TMEM102 C16orf54

4.11e-06189996b8cbfc47f3f40b6fccd15899d58c87d07b0001aa
ToppCellInfluenza_Severe-Non-classical_Monocyte|Influenza_Severe / Disease group and Cell class

METRNL POU2F2 IER5 ZDHHC1 FCGRT HES4

4.37e-06191996197edf6feb1cfc71d88e532d74f77305a42a3486
ToppCellsevere_COVID-19-Non-classical_Monocyte|severe_COVID-19 / disease group, cell group and cell class (v2)

METRNL ZDHHC1 RNPEP FCGRT HES4 NINJ1

5.07e-0619699634c1c74cad5e23196e86cfd6f19c836fe57b2264
ToppCellInfluenza_Severe-Non-classical_Monocyte|World / Disease group and Cell class

POU2F2 IER5 ZDHHC1 RNPEP FCGRT HES4

5.07e-061969968ef9810ee99082a9c803c7ecad6ceb5710d16b54
ToppCellCOVID-19_Severe-Non-classical_Monocyte|COVID-19_Severe / disease group, cell group and cell class

METRNL POU2F2 IER5 ZDHHC1 HES4 NINJ1

5.07e-06196996af9e8f5ef9d03862f707e105857309b55595b1b9
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

METRNL DOK2 ZDHHC1 FCGRT HES4 NINJ1

5.07e-0619699651fc8bb9a806f8fbf78d5d80d535f1068a9770c2
ToppCell10x5'-lymph-node_spleen-Myeloid_Monocytic-Nonclassical_monocytes|lymph-node_spleen / Manually curated celltypes from each tissue

ZDHHC1 FCGRT ASGR1 TSPO NINJ1 ADAMTSL4

5.22e-0619799667f19dd30adb03300f04219d0295bc1c1788f626
ToppCellHealthy/Control-Non-classical_Monocyte|World / Disease group and Cell class

POU2F2 IER5 ZDHHC1 FCGRT HES4 NINJ1

5.22e-06197996470784932e1fc3ff69f27cd83f56d85b0c01af63
ToppCell(3)_Monocyte|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

IER5 ASGR1 NFKBIL1 TSPO HES4 NINJ1

5.37e-06198996dff753c3d6919ea9f504bdc9859ed542a5490a9d
ToppCellHealthy_donor-Non-classical_Monocyte|Healthy_donor / disease group, cell group and cell class (v2)

POU2F2 IER5 ZDHHC1 FCGRT HES4 NINJ1

5.37e-06198996d4eae333fa100db3ea2d4cbe7a1d6ab14816f0e2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

METRNL DOK2 ZDHHC1 FCGRT HES4 NINJ1

5.53e-0619999667bbb5268730453fcba16738dc1bad8b1610f2db
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

METRNL DOK2 ZDHHC1 FCGRT HES4 NINJ1

5.53e-06199996fa5ad81554969fffe5e779614d071d9194a7182c
ToppCellInfluenza-Influenza_Severe-Myeloid-CD16+_Monocyte|Influenza_Severe / Disease, condition lineage and cell class

METRNL POU2F2 IER5 ZDHHC1 FCGRT HES4

5.69e-062009961efdcfcd86e99fbe03db19a2a5ab10808eec282d
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAM83E PAPLN C6orf15 CYP4F12 FUT6

2.67e-05157995c43f2e1ea53b375a7432f17f87cfef3b2261003d
ToppCellMild_COVID-19-Myeloid-MoAM2|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

METRNL LINC02913 ASGR1 HES4 NINJ1

3.10e-05162995e5fc80ab19d513af6a7e677a5e67bfebca2e963b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD IER5 SEZ6L2 ADAMTS18 CYP4F12

3.79e-051699957c994653b0d629dfb046755d6b678452de0a15d2
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Fst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

JCAD IER5 SEMA5B NTN5 DISP3

4.60e-05176995a1b9f8f199a028b3fa85de43fe96bc29f387bfd8
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR162 EMILIN1 KRBA1 ASGR1 ACSM5

4.60e-051769955d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POU2F2 DOK2 RYR1 C11orf21 TMEM102

4.98e-05179995716856b2c7c660bf5ce00e63efeda6ed121f2baa
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM83E SEZ6L2 DISP3 RIMBP2 CCDC188

4.98e-05179995f2e8fc975c30992611630197b79daaeef7c4211d
ToppCelldroplet-Kidney-nan-21m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD SOST EMILIN1 CDC42EP1 CLEC14A

4.98e-05179995ba38177ffcf3a20f02afeeaaa91bc8eab8d1ac05
ToppCelldroplet-Kidney-nan-21m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD SOST EMILIN1 CDC42EP1 CLEC14A

4.98e-05179995d121351b4c3b91108e6c5753d18a44d676f38d4c
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

METRNL POU2F2 IER5 FCGBP GLS

5.53e-0518399562f76907e501bba6e1010b5c447faed5f0ef93a7
ToppCell3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ASGR1 SP5 RIMBP2 CCDC188 C16orf54

5.53e-0518399549f3ddc1c7c04b4ca837dbd6dad995add82941d6
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAM83E FCGBP PLIN5 HES4 FUT6

5.68e-0518499501c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PKDCC CDC42EP1 FCGBP PLIN5 C6orf15

5.82e-05185995c4ca213a59ffab183a7719c2b4bc3f658a95002d
ToppCellfacs-Heart-LA-24m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD SOST CLEC14A SP5 DLEU7

6.13e-05187995d9943e65eedab73d141eae524e2411653a751705
ToppCellfacs-Heart-LA-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD SOST CLEC14A SP5 DLEU7

6.13e-051879957b13c3b67d66f3afb410141d5471c9e78a4d8623
ToppCellMacrophages-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

DOK2 FCGRT NFKBIL1 TSPO ADAMTSL4

6.61e-051909958c49622a43422c07659f74edffe1ceab87621381
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

POU2F2 FCGBP FCGRT TSPO NINJ1

6.94e-05192995314d94d676d13f4ca0eea8ba222c7eb00946849c
ToppCellMacrophages-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

DOK2 FCGRT NFKBIL1 TSPO ADAMTSL4

7.11e-051939957254b730fc4e8b6837601141e37aa39ac680ecbb
ToppCellMacrophages-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

DOK2 FCGRT NFKBIL1 TSPO ADAMTSL4

7.11e-0519399518534bd60bdd1ce51f948380c78017679931b8b1
ToppCell390C-Myeloid-Monocyte-CD14+_Monocyte|390C / Donor, Lineage, Cell class and subclass (all cells)

METRNL FCGRT ASGR1 TSPO NINJ1

7.11e-05193995a50ee6110ea272d9d9f41d48bb5d43711cc00a32
ToppCellCOVID_vent-Myeloid-Monocytic-CD16+_Monocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

POU2F2 IER5 FCGRT HES4 NINJ1

7.29e-05194995b133d3d198360269cc449a75d34c29be377d91e0
ToppCellMonocytes-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

POU2F2 FCGRT NFKBIL1 TSPO NINJ1

7.29e-05194995ed14fbb3b4622798f8e02dc91bbe464a6fed8310
ToppCellMacrophages|World / lung cells shred on cell class, cell subclass, sample id

DOK2 FCGRT NFKBIL1 TSPO ADAMTSL4

7.29e-05194995baf7ae36826f04acb2b2975f80cd1287daec4261
ToppCellsevere_influenza-Non-classical_Monocyte|severe_influenza / disease group, cell group and cell class (v2)

POU2F2 IER5 ZDHHC1 FCGRT HES4

7.29e-051949957630e223666fb65743e21e045478f687dd739a54
ToppCellCOVID-19_Severe-Non-classical_Monocyte-|COVID-19_Severe / Disease condition and Cell class

POU2F2 IER5 DOK2 ZDHHC1 HES4

7.29e-05194995d70b9039fd2fef3e4be086513b94fb7e9bc1f670
ToppCellCOVID-19_Severe-Non-classical_Monocyte|COVID-19_Severe / Disease condition and Cell class

POU2F2 IER5 DOK2 ZDHHC1 HES4

7.29e-051949955151546812678ae85cb22224084d27b29e3c4724
ToppCellPBMC-Control|PBMC / Compartment, Disease Groups and Clusters

DOK2 ZDHHC1 FCGBP FCGRT C16orf54

7.47e-051959953cc4afa5f68f28336310d5f80a082cb8d98a5679
ToppCellBLOOD--(3)_Classical_Mono-1| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FCGRT ASGR1 NFKBIL1 TSPO CARS2

7.47e-051959954702d234731d4cd47d5fba570e439deee21c67f9
ToppCellmyeloid-CD14+_Monocyte|myeloid / Lineage and Cell class

IER5 ASGR1 TSPO NINJ1 CARS2

7.47e-0519599560fab0c24c827567fb42bbd7eb165bf45178c198
ToppCell343B-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SAV1 POU2F2 HES4 NINJ1 SLC16A7

7.47e-05195995d1ec768573929c717bb6b20ad5f26c4549cfcaed
ToppCell10x5'-blood-Myeloid_Monocytic-Nonclassical_monocytes|blood / Manually curated celltypes from each tissue

POU2F2 ZDHHC1 FCGRT HES4 NINJ1

7.47e-0519599588d65c7c3a28922c125bd9f7c403a55d7d4d83a9
ToppCellInt-URO-Myeloid-CD16_Mono|Int-URO / Disease, Lineage and Cell Type

POU2F2 IER5 FCGRT HES4 NINJ1

7.65e-0519699510772fed1471974cb49155df1da46e4016192620
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

POU2F2 FCGBP FCGRT TSPO NINJ1

7.65e-05196995efdc95811e8b17243065ae82d748ea2c5775fdbc
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

POU2F2 FCGBP FCGRT TSPO NINJ1

7.65e-051969953392efa5007736b1e87f34805c16e8baa792e596
ToppCellmyeloid-CD16+_Monocyte|World / Lineage and Cell class

POU2F2 ZDHHC1 FCGRT HES4 NINJ1

7.65e-05196995225c102e0a2047425a7125eba1d2359159c50409
ToppCellmyeloid-CD14+_Monocyte|World / Lineage and Cell class

IER5 FCGRT ASGR1 TSPO NINJ1

7.65e-05196995b70f9402a1707671c0dd44226fa2adfc4bde8283
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN1 CDC42EP1 FCGRT CLEC14A SORBS3

7.65e-0519699581900dcc9451ff6606ec940c16b559d73247590e
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

METRNL IER5 FCGRT HES4 NINJ1

7.65e-0519699529246378ffb1010fe6858da756ae3d13df2306ba
ToppCell(3)_MNP|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

IER5 FCGRT ASGR1 NFKBIL1 TSPO

7.65e-05196995c79403da5443710a6caf035a279e42bc324b27c9
ToppCell10x3'2.3-week_17-19-Myeloid_macrophage-stroma-stromal_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

DOK2 FCGBP FCGRT ACSM5 NINJ1

7.65e-0519699588517bb92be2f05c1e1ad94af22ac10d8c5c13c7
ToppCellfacs-Brain_Non-Myeloid|facs / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD APBB1 SEZ6L2 CDC42EP1 SORBS3

7.84e-05197995a1f7eec1aca03432caa8fe817ff6d24b29d4062d
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOK2 FCGRT ASGR1 TSPO ADAMTSL4

7.84e-05197995aec598543d9a6bd20670bc9855d6531a5ba995fa
ToppCellCOVID-19_Severe-Myeloid-Non-classical_Monocyte|COVID-19_Severe / Disease group, lineage and cell class

POU2F2 IER5 ZDHHC1 FCGRT HES4

7.84e-05197995c5837b9a5a39a0f607a4e217ade9fc87d82a5406
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

METRNL FCGRT ASGR1 HES4 NINJ1

7.84e-05197995383d598ce3f8f5fc98bef3300e4cf7b6992aec9c
ToppCell10x5'-bone_marrow-Myeloid_Monocytic-Nonclassical_monocytes|bone_marrow / Manually curated celltypes from each tissue

POU2F2 ZDHHC1 FCGRT HES4 NINJ1

7.84e-05197995dcf1e74b7c21466d38d68f44d404bce14ade2805
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

METRNL FCGRT ASGR1 HES4 NINJ1

7.84e-051979953cc4e56a77f96a43f9b5a24cf1b9524c927ef795
ToppCell343B-Myeloid|343B / Donor, Lineage, Cell class and subclass (all cells)

IER5 FCGRT ASGR1 TSPO ADAMTSL4

7.84e-0519799550c7dff900f806a292b39aade60669b9db882347
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Monocytes,_Macrophages|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

METRNL POU2F2 DOK2 TSPO NINJ1

8.03e-051989957490b30462d03b5edee3bcacdef9483dd15821b5
ToppCellPBMC-Severe-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

POU2F2 IER5 ZDHHC1 FCGRT HES4

8.03e-051989959b8679b3dd8f4220d71f607b7080cb88d6e71129
ToppCellPBMC-Severe-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

POU2F2 IER5 ZDHHC1 FCGRT HES4

8.03e-051989958b6b602ebe59b6dca6a22f17385d3160ff3ac67e
ToppCellICU-SEP-Myeloid-CD16_Mono|ICU-SEP / Disease, Lineage and Cell Type

POU2F2 IER5 FCGRT HES4 NINJ1

8.03e-051989953e6f262ec71e99a5dadbaaeaff1b4f1894907c7d
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

METRNL POU2F2 DOK2 TSPO NINJ1

8.03e-051989954f86ff6ba8cbe987e7541fca4f3ae8d0e434677d
ToppCell356C-Myeloid-Monocyte-CD14+_Monocyte|356C / Donor, Lineage, Cell class and subclass (all cells)

IER5 ASGR1 TSPO HES4 NINJ1

8.03e-051989958f53df66712c0b4a176098c0dbb3c2c13d3f56df
ToppCellPBMC-Severe-Myeloid-Non-classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

POU2F2 IER5 ZDHHC1 FCGRT HES4

8.03e-05198995b9030390316baf456135f85f831394e1e11ecf3e
ToppCell(0)_Myeloid-(01)_Dendritic_cell-(010)_cDC|(01)_Dendritic_cell / immune cells in Peripheral Blood (logTPM normalization)

METRNL POU2F2 DOK2 NFKBIL1 TSPO

8.03e-051989954abc274edac40f8836255fac2371ffd98a32cccd
ToppCellLPS_anti-TNF-Hematopoietic_Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

METRNL POU2F2 DOK2 TSPO NINJ1

8.03e-0519899539e52fcd467b8041da977cfe25764df02a87990a
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

POU2F2 IER5 DOK2 ASGR1 TSPO

8.03e-05198995c00dbe61dc25602f19bd42a760646680002961ca
ToppCellLPS_anti-TNF-Hematopoietic_Myeloid-Monocytes,_Macrophages|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

METRNL POU2F2 DOK2 TSPO NINJ1

8.03e-05198995b32ca1b5d88b13a39f2cd4e129ea031f97475d29
ToppCellPBMC-Severe-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

POU2F2 IER5 ZDHHC1 FCGRT HES4

8.03e-05198995d36a3cda7e5f385d2391e9b0dfb027d3c4549320
ToppCellPBMC-Severe-Myeloid-Non-classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

POU2F2 IER5 ZDHHC1 FCGRT HES4

8.03e-051989955436c3ed16e10e00c686f1ab0b0a68728a1a9985
ToppCellsevere_influenza-Non-classical_Monocyte|World / disease group, cell group and cell class (v2)

POU2F2 ZDHHC1 RNPEP FCGRT HES4

8.03e-05198995790ee20abc9666b8095675b0d445c0914ee70ea3
ToppCell390C-Myeloid-Dendritic-cDC2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

METRNL DOK2 TSPO HES4 NINJ1

8.03e-051989958b28e6630dcffa7ca32e959a50f94a0370b78ae0
ToppCellHealthy_donor-Non-classical_Monocyte|World / disease group, cell group and cell class (v2)

POU2F2 ZDHHC1 FCGRT HES4 ADAMTSL4

8.03e-051989958a97c8b2a43e6d1e669ce18752841e2006744bd9
ToppCell356C-Myeloid-Monocyte|356C / Donor, Lineage, Cell class and subclass (all cells)

IER5 ASGR1 TSPO HES4 NINJ1

8.03e-05198995ad5b9a92f3ad7f4220f173cee4dba0977bd803fe
ToppCellNS-critical-d_0-4-Myeloid-Non-resident_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

POU2F2 DOK2 CEP170 FCGRT NMT1

8.03e-0519899549fc6ba574ed5c848eaa329aad1d5c8091c79f47
ToppCellPBMC-Severe-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

POU2F2 IER5 ZDHHC1 FCGRT HES4

8.03e-051989954f67067d8142ca11b2d80195dac8d62a8d24d52c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

METRNL FCGRT ASGR1 TSPO NINJ1

8.03e-05198995de21168c9c05873938cc65e82cce40ffd8e55df1
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

METRNL FCGBP FCGRT TSPO NINJ1

8.22e-05199995e225c1bfc55947c30e7948be851daea04975efa5
ToppCelldistal-Hematologic-Interstitial_Macrophage-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

METRNL POU2F2 CEP170 ASGR1 NINJ1

8.22e-05199995e25a67a196f226b60b4aa0ff0cf4471d66333445
ToppCellSevere_COVID-19-Myeloid-MoAM3|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

CEP170 FCGRT ASGR1 TSPO ADAMTSL4

8.22e-0519999530523cf08815ca214877e33a2c52197ff8318557
ToppCellBAL-Severe-Myeloid-MoAM-MoAM3|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CEP170 FCGRT ASGR1 TSPO ADAMTSL4

8.22e-05199995105709b97c55826a852aed27658e3b4af1738c8a
ToppCellCOVID-19-Myeloid-MoAM3,_VCAN|COVID-19 / Condition, Lineage and Cell class

CEP170 FCGRT ASGR1 TSPO ADAMTSL4

8.22e-05199995aba0b833e44fe42625fac91466f6ebaa8e786d3b
ToppCellBAL-Severe-Myeloid-MoAM-MoAM3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CEP170 FCGRT ASGR1 TSPO ADAMTSL4

8.22e-051999950892957a49304ce4b6daa3657d76d8365ce0dd19
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

METRNL FCGRT ASGR1 TSPO ADAMTSL4

8.22e-0519999587956fcb39c2e3e99622ff05f99267d7621a78fc
ToppCellBAL-Severe-Myeloid-MoAM-MoAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CEP170 FCGRT ASGR1 TSPO ADAMTSL4

8.22e-05199995b2dc3d0af6ecd3ab01779aaa1f061cb0f941cae8
ToppCellBAL-Severe-Myeloid-MoAM-MoAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CEP170 FCGRT ASGR1 TSPO ADAMTSL4

8.22e-05199995961ad44199871be8e09d31904d383edc865ba262
ToppCellmild_COVID-19_(asymptomatic)-Classical_Monocyte|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

POU2F2 FCGRT ASGR1 TSPO NINJ1

8.22e-0519999573a98d19871ffbc3c631de330998d42e9afa6da2
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

POU2F2 IER5 ZDHHC1 FCGRT HES4

8.22e-05199995df946601b295be5419c09befbfa73f4314eef116
ToppCellBAL-Severe-cDC_0|Severe / Compartment, Disease Groups and Clusters

DOK2 FCGRT ASGR1 TSPO ADAMTSL4

8.22e-05199995d39be8b173156bf87baddd3caed4b35597c53ea1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

METRNL DOK2 ZDHHC1 FCGRT HES4

8.41e-0520099552f2a97af2d77dd068b19531dad1b3fba2601e90
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

METRNL DOK2 FCGRT TSPO NINJ1

8.41e-05200995b719af4e821f371459344693458bfd316cc2b37c
ToppCellParenchymal-10x5prime-Immune_Myeloid-Monocytic-Monocyte_CD14|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

METRNL POU2F2 ASGR1 TSPO NINJ1

8.41e-0520099547a3fd432c35958c5d478d34f5e0355e39ed0aba
Diseaseserum carcinoembryonic antigen measurement

FAM83E FUT5 FUT6

3.65e-0520963EFO_0005760
Diseasealpha-(1;3)-fucosyltransferase 5 measurement

FUT5 FUT6

6.26e-054962EFO_0021979
Diseasegalactoside 3(4)-L-fucosyltransferase measurement

FUT5 FUT6

2.18e-047962EFO_0021853
Diseasealpha-(1,3)-fucosyltransferase 5 measurement

FUT5 FUT6

2.18e-047962EFO_0020136
Diseaseresponse to vitamin

CYP4F2 GPR162

2.90e-048962GO_0033273
Diseaseasparaginase-induced acute pancreatitis

ADAMTS18 CDC20

3.72e-049962EFO_1001507
Diseasekidney cancer (implicated_via_orthology)

SAV1 SCRIB

5.65e-0411962DOID:263 (implicated_via_orthology)
Diseaseprotein FAM3D measurement

FAM83E NTN5

6.77e-0412962EFO_0021869
Diseasetumor necrosis factor measurement

APBB1 NFKBIL1

1.07e-0315962EFO_0010834
Diseaseuridine diphosphate galactose measurement, uridine diphosphate glucose measurement

JCAD ADAMTS18

1.38e-0317962EFO_0010543, EFO_0010544
DiseaseMHC class I polypeptide-related sequence A measurement

POU5F1 C6orf15 NFKBIL1

1.43e-0368963EFO_0008233
Diseaseleft ventricular mass

SEZ6L2 ADAMTS10

1.55e-0318962EFO_0009289

Protein segments in the cluster

PeptideGeneStartEntry
WTGPGPATHWPLYAQ

nan

16

Q75L30
WRPEQPDDWYGHGLG

ASGR1

236

P07306
PRGTPLYGQPSWWGD

CEP170

171

Q5SW79
MGPSWGQHPGHWGFP

ERI3

36

O43414
WEGGIRVPGIFHWPG

ARSD

386

P51689
WPSAPGEGGWVPLQT

CDC20

336

Q12834
PQPGAGGQCCWRHWP

DISP3

36

Q9P2K9
GFEFDRWLNTPGWPP

RNPEP

476

Q9H4A4
PTEEGQGPEGVWGPW

ADAMTSL4

36

Q6UY14
TRHFPWSPFPHGGWT

BLACE

101

A4D250
VWGGGLSPRNPHSWG

DNAH10OS

66

P0CZ25
PGFAIWAPLPHWRGT

CDRT15P3

126

P0DPF6
FWGPQPWEGRPPATG

C16orf54

151

Q6UWD8
HRPPNPAFWWVNGTG

ACSM5

71

Q6NUN0
WHIPTGTTQWEPPGR

APBB1

271

O00213
HGPGFWFQPPVCSNW

CCER1

71

Q8TC90
SRPEGVDGAWGPWTP

ADAMTS10

541

Q9H324
GELGPRPIHGQWSAW

ADAMTS18

581

Q8TE60
DDQSHWRYGGDPPWP

CA9

136

Q16790
WRYGGDPPWPRVSPA

CA9

141

Q16790
SWGHLVPLQEAWGPP

POLN

851

Q7Z5Q5
LPTWHSWTPGRGGEP

TSPOAP1

21

O95153
SPPEPWGWPLLGHVL

CYP1A2

41

P05177
GVPVGHWPIPESFWP

INTS6L

281

Q5JSJ4
AGPAAAARLHPWWGG

GLS

46

O94925
ALGWAAPGGPREPWA

ABCC10

186

Q5T3U5
LWGGPEPGTQLYDWP

DOK2

181

O60496
PRWAHGPGHRHLPYW

KRBA1

861

A5PL33
LRPPGWLPQWHCGVR

NMT1

201

P30419
SWTPFPPDLWGPGRS

FAAP20

86

Q6NZ36
AWGGSWGPGNPIFPQ

GPR162

571

Q16538
QEWGWGDGPVAPGNP

DLEU7

26

Q6UYE1
SPRWLWGQPPGDGEN

JCAD

496

Q9P266
APGTPAFWVSGWLGP

FCGRT

41

P55899
AWAGGARPGPGVWDP

PGAM5

46

Q96HS1
GPDGQWVRGPRGQPW

GCGR

101

P47871
GLNPSTGPGLWWNPA

POU2F2

461

P09086
WRIPLGPLPHEFRGW

POU5F2

61

Q8N7G0
HPPPDGGWGWIVVGA

SLC16A7

11

O60669
RAAWGRAGQPWPRPP

METRNL

6

Q641Q3
ETPGQILGWGPPWDS

NFKBIL1

136

Q9UBC1
IHWSWPLQGERPFGP

NLRX1

31

Q86UT6
GPGGPEPGWVDPRTW

POU5F1

21

Q01860
SPDASPARWGWRHGP

NINJ1

21

Q92982
PTWPWPGELGPHAGL

OBSCN

7351

Q5VST9
GGSAVQRWPPSWGLP

C6orf15

91

Q6UXA7
RWRPHSPDGPRSAGW

GIGYF2

231

Q6Y7W6
GPVGGPHAWWVPPTA

LINC01599

261

Q8WXQ3
APSIPIWGGSWRAPG

FCGBP

4236

Q9Y6R7
DLEAGLGWGWPLHPG

CCDC188

96

H7C350
LGWGWPLHPGSNQGA

CCDC188

101

H7C350
FPQPPKRNWFWGHLG

CYP4F12

51

Q9HCS2
PALSPHPGLWGQWAC

FAM25E

71

A8MYX2
GPAGPALGRHWGAGW

CDC42EP1

311

Q00587
FPQPPRRNWFWGHQG

CYP4F2

51

P78329
TPYGWLEPWSGQPAH

FUT6

166

P51993
RAGPQGPGGPWRPWL

HES4

206

Q9HCC6
WRPAAPAGPSVDPWG

EPN1

321

Q9Y6I3
APGAWGWARGAPRPP

GABBR2

36

O75899
GDVHWGNCRPGRWPV

CXorf38

96

Q8TB03
DPGSQVEPSWPWHPG

LINC02913

126

Q8NAJ2
ESWPGAPGGLSHWLP

EMILIN1

426

Q9Y6C2
WHLGSEPFGRPWQPG

RYR1

1131

P21817
PLGWGPGPQHAPFWS

PPRC1

981

Q5VV67
GQKWGWHRGEPGHPR

KLHL30-AS1

41

Q8NEE0
VGGSAAPPGAWPWLV

PRSS56

106

P0CW18
GWGNTYPQWQPPAPH

KHSRP

546

Q92945
PYGWLEPWSGQPAHP

FUT5

181

Q11128
AGWGEPPPPAARASW

IER5

81

Q5VY09
GWEPPAVPPGWGTVS

RIMBP2

316

O15034
FWASPWGPGRPGWHI

CARS2

241

Q9HA77
PGLLPWYARNPPGWS

TRMT2B

26

Q96GJ1
DLPWWSIPQAGAGPG

SP5

186

Q6BEB4
RPPWARPLSDGAPGW

PKDCC

101

Q504Y2
GPWGEVDSRPPWGGA

FAM83E

416

Q2M2I3
WHRPAWPGALGGPER

NTN5

106

Q8WTR8
WWGVNAEPPFPGPGH

PRR3

101

P79522
AFPAAWEAWPRGPGG

SH2D5

266

Q6ZV89
PEGWQRGGPFWPQVT

PSD4

396

Q8NDX1
APDPAWDWQHVGPGY

NOL3

86

O60936
ELPPPEWGWRTASHG

SEZ6L2

646

Q6UXD5
APGGWHNGPHAPWAP

SCRIB

641

Q14160
FGSCPPEEQPRGWWF

OVCA2

61

Q8WZ82
KGPANWPWVAPGRGA

PROB1

51

E7EW31
WPWVAPGRGAGAQPR

PROB1

56

E7EW31
PNAIGRGKWWRPSGP

SOST

116

Q9BQB4
RSWGWAAVPFGPHRG

ABHD10

16

Q9NUJ1
WAGGRPPWPVSGVLG

AURKAIP1

16

Q9NWT8
WQALWPGPGGGEHPT

CLEC14A

11

Q86T13
GVEPPDRWTGTPGWP

C11orf21

31

Q9P2W6
HWSHPLEREGLPPGW

SAV1

226

Q9H4B6
GPWGPQDWVGPLPRG

USP19

1266

O94966
PGEAPHTQAFGEWPW

PAPLN

866

O95428
LARPWLGPWVPHGLS

SLC27A5

51

Q9Y2P5
GWPEGARSHSWAGPL

TMEM102

326

Q8N9M5
QHPDPAWYQTWPGPG

SORBS3

71

O60504
VTRDGGFGPWSPWQP

SEMA5B

606

Q9P283
GFGPWSPWQPCEHLD

SEMA5B

611

Q9P283
PPSRSHDGDRRGPWW

YLPM1

1251

P49750
GGPDPRWAHLDWPAQ

PLIN5

401

Q00G26
AWPGGLPPAQLQWEG

VSIG10L2

351

P0DP72
RGPGSEGVWEPGSWP

ZNF71

31

Q9NQZ8
GLQKPSWHPPHWVLG

TSPO

36

P30536
PQGRGSWISPQPGPW

TPRX2

116

P0DV77
GQRSRRNGWSWPPHP

ZDHHC1

36

Q8WTX9
PLWPPRGAGADSPRW

ZDHHC1

461

Q8WTX9
LLHWAGPGGGEPWVT

TYK2

31

P29597
PQRRGGPSWWPPSGV

nan

81

Q6ZSA8
WPGSPGWRLARGPAH

nan

76

Q6ZPA2