Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphenanthrene-9,10-epoxide hydrolase activity

AKR7A2 AKR7L

1.12e-0431232GO:0019119
GeneOntologyMolecularFunctionphenanthrene-epoxide hydrolase activity

AKR7A2 AKR7L

1.12e-0431232GO:0019118
DomainIPT

PLXNA3 RELA MST1R PLXNC1

2.89e-05271244SM00429
DomainASH

ASPM HYDIN

4.37e-0521242IPR031549
DomainASH

ASPM HYDIN

4.37e-0521242PF15780
DomainTIG

PLXNA3 RELA MST1R PLXNC1

5.07e-05311244PF01833
DomainIPT

PLXNA3 RELA MST1R PLXNC1

5.76e-05321244IPR002909
DomainHEAT_REPEAT

IPO5 MROH2A SF3B1 UTP20 KPNB1

1.02e-04701245PS50077
DomainNMDAR2_C

GRIN2A GRIN2B

1.31e-0431242PF10565
DomainNMDAR2_C

GRIN2A GRIN2B

1.31e-0431242IPR018884
DomainDUF1605

DHX57 DHX9 DHX29

1.81e-04171243IPR011709
DomainOB_NTP_bind

DHX57 DHX9 DHX29

1.81e-04171243PF07717
DomainHA2

DHX57 DHX9 DHX29

2.17e-04181243SM00847
DomainHA2

DHX57 DHX9 DHX29

2.17e-04181243PF04408
DomainHelicase-assoc_dom

DHX57 DHX9 DHX29

2.17e-04181243IPR007502
DomainHEAT

IPO5 SF3B1 UTP20 KPNB1

2.87e-04481244PF02985
DomainMunc13_dom-2

UNC13B BAIAP3

4.32e-0451242IPR014772
DomainMHD2

UNC13B BAIAP3

4.32e-0451242PS51259
DomainMunc13_subgr_dom-2

UNC13B BAIAP3

4.32e-0451242IPR019558
DomainMembr_traf_MHD

UNC13B BAIAP3

4.32e-0451242PF10540
DomainARM-type_fold

IPO5 MROH2A URB1 SF3B1 PIK3CG ASPM UTP20 WDFY3 KPNB1

4.38e-043391249IPR016024
Domain-

UNC13B PLA2G4E PIK3CG C2CD4D CPNE3 BAIAP3

4.64e-0414812462.60.40.150
DomainHEAT

IPO5 SF3B1 UTP20 KPNB1

5.95e-04581244IPR000357
DomainC2_dom

UNC13B PLA2G4E PIK3CG C2CD4D CPNE3 BAIAP3

7.96e-041641246IPR000008
DomainMunc13_1

UNC13B BAIAP3

8.98e-0471242IPR014770
DomainMHD1

UNC13B BAIAP3

8.98e-0471242PS51258
DomainDUF1041

UNC13B BAIAP3

8.98e-0471242PF06292
DomainCAPS_dom

UNC13B BAIAP3

8.98e-0471242IPR010439
DomainC1

UNC13B CDC42BPG PRKD3 KMT2C

9.17e-04651244SM00109
DomainPE/DAG-bd

UNC13B CDC42BPG PRKD3 KMT2C

9.71e-04661244IPR002219
DomainSemap_dom

PLXNA3 MST1R PLXNC1

1.12e-03311243IPR001627
DomainSEMA

PLXNA3 MST1R PLXNC1

1.12e-03311243PS51004
DomainSema

PLXNA3 MST1R PLXNC1

1.12e-03311243SM00630
DomainSema

PLXNA3 MST1R PLXNC1

1.12e-03311243PF01403
DomainPlexin_repeat

PLXNA3 MST1R PLXNC1

1.23e-03321243IPR002165
DomainPSI

PLXNA3 MST1R PLXNC1

1.23e-03321243PF01437
DomainIQ

MYO1D IQCN MYO3A ASPM

1.28e-03711244PF00612
DomainPlexin_cytopl

PLXNA3 PLXNC1

1.53e-0391242PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA3 PLXNC1

1.53e-0391242IPR013548
DomainPlexin

PLXNA3 PLXNC1

1.53e-0391242IPR031148
DomainDNA/RNA_helicase_DEAH_CS

DHX57 DHX9 DHX29

1.60e-03351243IPR002464
DomainC2

UNC13B PLA2G4E C2CD4D CPNE3 BAIAP3

1.82e-031311245PF00168
DomainDEAH_ATP_HELICASE

DHX57 DHX9 DHX29

2.03e-03381243PS00690
DomainIQ

MYO1D IQCN MYO3A ASPM

2.08e-03811244SM00015
DomainARM-like

IPO5 MROH2A SF3B1 ASPM UTP20 WDFY3 KPNB1

2.19e-032701247IPR011989
DomainC2

UNC13B PLA2G4E C2CD4D CPNE3 BAIAP3

2.21e-031371245SM00239
DomainC2

UNC13B PLA2G4E C2CD4D CPNE3 BAIAP3

2.58e-031421245PS50004
DomainIQ_motif_EF-hand-BS

MYO1D IQCN MYO3A ASPM

3.05e-03901244IPR000048
DomainPSI

PLXNA3 MST1R PLXNC1

3.10e-03441243IPR016201
DomainIQ

MYO1D IQCN MYO3A ASPM

3.43e-03931244PS50096
DomainPSI

PLXNA3 MST1R PLXNC1

3.52e-03461243SM00423
Domain-

IPO5 SF3B1 ASPM UTP20 WDFY3 KPNB1

3.68e-0322212461.25.10.10
DomainIMPORTIN_B_NT

IPO5 KPNB1

3.78e-03141242PS50166
DomainIg_E-set

PLXNA3 RELA MST1R PLXNC1

5.11e-031041244IPR014756
DomainNADP_OxRdtase_dom

AKR7A2 AKR7L

5.57e-03171242IPR023210
DomainImportin-beta_N

IPO5 KPNB1

5.57e-03171242IPR001494
DomainAldo_ket_red

AKR7A2 AKR7L

5.57e-03171242PF00248
DomainAldo/ket_red/Kv-b

AKR7A2 AKR7L

5.57e-03171242IPR001395
DomainZnF_C2HC

TUT4 FAM90A27P RTL4

5.83e-03551243SM00343
DomainZnf_CCHC

TUT4 FAM90A27P RTL4

5.83e-03551243IPR001878
DomainLig_chan-Glu_bd

GRIN2A GRIN2B

6.24e-03181242PF10613
DomainGlu/Gly-bd

GRIN2A GRIN2B

6.24e-03181242IPR019594
DomainLig_chan-Glu_bd

GRIN2A GRIN2B

6.24e-03181242SM00918
DomainIontro_rcpt

GRIN2A GRIN2B

6.24e-03181242IPR001320
DomainIono_rcpt_met

GRIN2A GRIN2B

6.24e-03181242IPR001508
DomainLig_chan

GRIN2A GRIN2B

6.24e-03181242PF00060
DomainPBPe

GRIN2A GRIN2B

6.24e-03181242SM00079
DomainC1_1

UNC13B CDC42BPG PRKD3

6.44e-03571243PF00130
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

KIF23 RPS5 KDM3B ANKHD1 DHX9 GMPS SF3B1 BRCA2 MKI67 EHMT1 CCT8 SLX4IP SLX4 KPNB1

7.53e-113571291437059091
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

IPO5 KIF23 MYO1D RPS5 PSMC2 DHX57 RPS23 ANKHD1 GMPS URB1 SF3B1 MKI67 SMARCC2 UTP20 VCL KPNB1

2.98e-096531291622586326
Pubmed

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells.

MYC RBL2 PPARGC1A KLF10 N4BP1 VGLL4 CDC6

1.09e-0873129722094256
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MYC KIF23 RPS5 PSMC2 DHX57 RPS23 ANKHD1 DHX9 GMPS URB1 SF3B1 CPNE3 MKI67 ASPM CCT8 SMARCC2 UTP20 WDFY3 DHX29 VCL KPNB1

2.81e-0813531292129467282
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

MYC KIF23 USP28 RPS5 CYP51A1 PSMC2 RPS23 DHX9 URB1 SF3B1 KLF10 MKI67 NFYC CCT8 SMARCC2 UTP20 VCL KPNB1

2.88e-089891291836424410
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

IPO5 KIF23 RPS5 PSMC2 RPS23 DHX9 GMPS SF3B1 MKI67 CCT8 SMARCC2 VCL KPNB1

4.32e-084941291326831064
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

KDM3B TRIOBP SMG5 MED13L KMT2C URB1 EHMT1 WDFY3 BAIAP3

1.77e-07225129912168954
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

IPO5 TUT4 CTTNBP2 RPS5 RPS23 DHX9 SF3B1 CPNE3 KPNB1

2.55e-07235129930258100
Pubmed

Human transcription factor protein interaction networks.

MYC KIF23 MYO1D RPS5 PSMC2 RELA SMG5 ANKHD1 KMT2C KLF10 BANP MKI67 NFYC EHMT1 SLX4IP SMARCC2 N4BP1 VGLL4 SLX4 VCL

3.27e-0714291292035140242
Pubmed

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.

MYC CDC42BPG MYO1D RPS5 PSMC2 RPS23 DHX9 SF3B1 TONSL

6.77e-07264129932814769
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

IPO5 CDC42BPG PNKP KIF23 MYO1D RPS5 PSMC2 RPS23 MED13L DHX9 GMPS SF3B1 MKI67 CCT8 SMARCC2 CDH3 VCL KPNB1

8.70e-0712471291827684187
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

MYC KIF23 USP28 MED13L SF3B1 FAM111A BRCA2 TONSL SLX4IP SMARCC2 SLX4

1.09e-064531291129656893
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

IPO5 KIF23 ZFYVE16 RPS5 CYP51A1 KDM3B PSMC2 RPS23 ANKHD1 DHX9 AKR7A2 GMPS SF3B1 MKI67 EHMT1 CCT8 SMARCC2 KPNB1

1.52e-0612971291833545068
Pubmed

Subunits of the heterotrimeric transcription factor NF-Y are imported into the nucleus by distinct pathways involving importin beta and importin 13.

IPO5 NFYC KPNB1

1.73e-067129315964792
Pubmed

Mechanism of KMT5B haploinsufficiency in neurodevelopment in humans and mice.

GRIN2B MKI67 WDFY3

1.73e-067129336897941
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

KIF23 ZFYVE16 USP28 KDM3B PSMC2 RPS23 ANKHD1 GMPS SF3B1 CPNE3 MKI67 CCT8 DHX29 VCL KPNB1

2.12e-069341291533916271
Pubmed

Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis.

MYC MKI67 CDH3

2.75e-068129319427292
Pubmed

A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.

MYC KMT2C SF3B1 CCT8 SMARCC2

3.27e-0661129520305087
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

UNC13B PLXNA3 KDM3B SMG5 MED13L ANKHD1 MST1R PLEKHG1 KMT2C URB1 KLF10 BANP EHMT1 WDFY3 ELL GAREM1

3.58e-0611051291635748872
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

DHX57 DHX9 SF3B1 MKI67 SMARCC2 DHX29 VCL KPNB1

4.59e-06250129833536335
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

MYC IPO5 PNKP KIF23 USP28 KDM3B MED13L DHX9 GMPS SF3B1 CPNE3 MKI67 EHMT1 CCT8 SMARCC2

5.71e-0610141291532416067
Pubmed

The transcription factor NF-YA is crucial for neural progenitor maintenance during brain development.

MKI67 ASPM NFYC

8.05e-0611129338199563
Pubmed

Large-scale genotyping identifies 41 new loci associated with breast cancer risk.

MYC SLC25A21 NTN4 BRCA2 ELL

9.71e-0676129523535729
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

SLC25A21 TUT4 RBL2 ITPRID1 ANKHD1 PTPRZ1 LMLN SSX2IP PAN2 ELMOD3 DHX29 HYDIN

1.01e-056861291229987050
Pubmed

Functional proteomics mapping of a human signaling pathway.

PNKP ZFYVE16 KDM3B PSMC2 CBLB MTMR10 SF3B1 KLF10 ZNF587 VCL KPNB1

1.36e-055911291115231748
Pubmed

The glutamate receptor GluN2 subunit regulates synaptic trafficking of AMPA receptors in the neonatal mouse brain.

GRIN2A GRIN2B

1.37e-052129225131300
Pubmed

Knockdown of Ron kinase inhibits mutant phosphatidylinositol 3-kinase and reduces metastasis in human colon carcinoma.

MST1R PIK3CG

1.37e-052129219224914
Pubmed

Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms.

GRIN2A GRIN2B

1.37e-052129220921396
Pubmed

The GRIN2B and GRIN2A Gene Variants Are Associated With Continuous Performance Test Variables in ADHD.

GRIN2A GRIN2B

1.37e-052129227199241
Pubmed

The role of NMDAR subtypes and charge transfer during hippocampal LTP induction.

GRIN2A GRIN2B

1.37e-052129216901514
Pubmed

Disruption of an EHMT1-associated chromatin-modification module causes intellectual disability.

KMT2C EHMT1

1.37e-052129222726846
Pubmed

Specific involvement of postsynaptic GluN2B-containing NMDA receptors in the developmental elimination of corticospinal synapses.

GRIN2A GRIN2B

1.37e-052129220696923
Pubmed

NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.

GRIN2A GRIN2B

1.37e-052129223618906
Pubmed

Both NR2A and NR2B subunits of the NMDA receptor are critical for long-term potentiation and long-term depression in the lateral amygdala of horizontal slices of adult mice.

GRIN2A GRIN2B

1.37e-052129219474217
Pubmed

A novel form of the RelA nuclear factor kappaB subunit is induced by and forms a complex with the proto-oncogene c-Myc.

MYC RELA

1.37e-052129212027803
Pubmed

Importance of the GluN2B carboxy-terminal domain for enhancement of social memories.

GRIN2A GRIN2B

1.37e-052129226179233
Pubmed

Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiation.

GRIN2A GRIN2B

1.37e-052129216033900
Pubmed

Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids.

GRIN2A GRIN2B

1.37e-052129238214768
Pubmed

[Different distribution of NMDA receptor subunits in cortex contributes to selective vulnerability of motor neurons in amyotrophic lateral sclerosis].

GRIN2A GRIN2B

1.37e-052129221503117
Pubmed

Functional contributions of synaptically localized NR2B subunits of the NMDA receptor to synaptic transmission and long-term potentiation in the adult mouse CNS.

GRIN2A GRIN2B

1.37e-052129218372311
Pubmed

Effects of GluN2A and GluN2B gain-of-function epilepsy mutations on synaptic currents mediated by diheteromeric and triheteromeric NMDA receptors.

GRIN2A GRIN2B

1.37e-052129232247039
Pubmed

NF-κB downregulates Cbl-b through binding and suppressing Cbl-b promoter in T cell activation.

RELA CBLB

1.37e-052129225762784
Pubmed

Ubiquitination and functional modification of GluN2B subunit-containing NMDA receptors by Cbl-b in the spinal cord dorsal horn.

GRIN2B CBLB

1.37e-052129232606037
Pubmed

Separate functional properties of NMDARs regulate distinct aspects of spatial cognition.

GRIN2A GRIN2B

1.37e-052129229764972
Pubmed

Increasing the GluN2A/GluN2B Ratio in Neurons of the Mouse Basal and Lateral Amygdala Inhibits the Modification of an Existing Fear Memory Trace.

GRIN2A GRIN2B

1.37e-052129227605622
Pubmed

Disease-associated GRIN protein truncating variants trigger NMDA receptor loss-of-function.

GRIN2A GRIN2B

1.37e-052129233043365
Pubmed

The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences.

GRIN2A GRIN2B

1.37e-052129230355491
Pubmed

N-methyl-D-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease.

GRIN2A GRIN2B

1.37e-052129212127670
Pubmed

Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes.

GRIN2A GRIN2B

1.37e-052129220890276
Pubmed

Roles of NMDA receptor NR2A and NR2B subtypes for long-term depression in the anterior cingulate cortex.

GRIN2A GRIN2B

1.37e-052129216045501
Pubmed

NR2A- and NR2B-NMDA receptors and drebrin within postsynaptic spines of the hippocampus correlate with hunger-evoked exercise.

GRIN2A GRIN2B

1.37e-052129227915379
Pubmed

Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory.

GRIN2A GRIN2B

1.37e-052129232179753
Pubmed

Virally mediated knock-down of NR2 subunits ipsilateral to the deprived eye blocks ocular dominance plasticity.

GRIN2A GRIN2B

1.37e-052129216944113
Pubmed

Attenuation of focal ischemic brain injury in mice deficient in the epsilon1 (NR2A) subunit of NMDA receptor.

GRIN2A GRIN2B

1.37e-05212929822733
Pubmed

Endothelin-1 enhances the expression of the androgen receptor via activation of the c-myc pathway in prostate cancer cells.

MYC EDN1

1.37e-052129218623111
Pubmed

RNA helicase A interacts with nuclear factor kappaB p65 and functions as a transcriptional coactivator.

RELA DHX9

1.37e-052129215355351
Pubmed

NR2A and NR2B receptor gene variations modify age at onset in Huntington disease.

GRIN2A GRIN2B

1.37e-052129215742215
Pubmed

Cell cycle-dependent switch of up-and down-regulation of human hsp70 gene expression by interaction between c-Myc and CBF/NF-Y.

MYC NFYC

1.37e-052129210446203
Pubmed

Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice.

GRIN2A GRIN2B

1.37e-052129237657442
Pubmed

Individual NMDA receptor GluN2 subunit signaling domains differentially regulate the postnatal maturation of hippocampal excitatory synaptic transmission and plasticity but not dendritic morphology.

GRIN2A GRIN2B

1.37e-052129238813758
Pubmed

Dual Role of NMDAR Containing NR2A and NR2B Subunits in Alzheimer's Disease.

GRIN2A GRIN2B

1.37e-052129238731978
Pubmed

Differential Nanoscale Topography and Functional Role of GluN2-NMDA Receptor Subtypes at Glutamatergic Synapses.

GRIN2A GRIN2B

1.37e-052129230269991
Pubmed

Downregulation of hippocampal NR2A/2B subunits related to cognitive impairment in a pristane-induced lupus BALB/c mice.

GRIN2A GRIN2B

1.37e-052129231498792
Pubmed

Age-Dependent Changes in Synaptic NMDA Receptor Composition in Adult Human Cortical Neurons.

GRIN2A GRIN2B

1.37e-052129232191258
Pubmed

Distinct roles of GRIN2A and GRIN2B variants in neurological conditions.

GRIN2A GRIN2B

1.37e-052129231807283
Pubmed

The role of GluN2A and GluN2B NMDA receptor subunits in AgRP and POMC neurons on body weight and glucose homeostasis.

GRIN2A GRIN2B

1.37e-052129226500840
Pubmed

Chronic early postnatal scream sound stress induces learning deficits and NMDA receptor changes in the hippocampus of adult mice.

GRIN2A GRIN2B

1.37e-052129227015584
Pubmed

MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells.

MYC PPARGC1A

1.37e-052129226365176
Pubmed

Hippocampal NMDA receptor subunits differentially regulate fear memory formation and neuronal signal propagation.

GRIN2A GRIN2B

1.37e-052129219806658
Pubmed

Subtype selective NMDA receptor antagonists induce recovery of synapses lost following exposure to HIV-1 Tat.

GRIN2A GRIN2B

1.37e-052129222142193
Pubmed

Conformational rearrangement of the NMDA receptor amino-terminal domain during activation and allosteric modulation.

GRIN2A GRIN2B

1.37e-052129233976221
Pubmed

Directional gating of synaptic plasticity by GPCRs and their distinct downstream signalling pathways.

GRIN2A GRIN2B

1.37e-052129222334046
Pubmed

Immunohistochemical evaluation of midkine and nuclear factor-kappa B as diagnostic biomarkers for papillary thyroid cancer and synchronous metastasis.

RELA MDK

1.37e-052129225283079
Pubmed

ELL targets c-Myc for proteasomal degradation and suppresses tumour growth.

MYC ELL

1.37e-052129227009366
Pubmed

Role of N-methyl-d-aspartate receptor subunits GluN2A and GluN2B in auditory thalamocortical long-term potentiation in adult mice.

GRIN2A GRIN2B

1.37e-052129234197904
Pubmed

Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memory.

GRIN2A GRIN2B

1.37e-052129216157280
Pubmed

N-Methyl-d-aspartic Acid (NMDA) Receptor Is Involved in the Inhibitory Effect of Ketamine on Human Sperm Functions.

GRIN2A GRIN2B

1.37e-052129234830255
Pubmed

Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder.

KMT2C EHMT1

1.37e-052129229069077
Pubmed

NMDA Receptor C-Terminal Domain Signalling in Development, Maturity, and Disease.

GRIN2A GRIN2B

1.37e-052129236232696
Pubmed

Opposing action of conantokin-G on synaptically and extrasynaptically-activated NMDA receptors.

GRIN2A GRIN2B

1.37e-052129222306487
Pubmed

Differential roles of NMDAR subunits 2A and 2B in mediating peripheral and central sensitization contributing to orofacial neuropathic pain.

GRIN2A GRIN2B

1.37e-052129236038077
Pubmed

The p65 subunit of NF-kappaB binds to PGC-1alpha, linking inflammation and metabolic disturbances in cardiac cells.

RELA PPARGC1A

1.37e-052129220211864
Pubmed

Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior.

GRIN2A GRIN2B

1.37e-052129223201971
Pubmed

Barrel cortex critical period plasticity is independent of changes in NMDA receptor subunit composition.

GRIN2A GRIN2B

1.37e-052129211719203
Pubmed

Analysis of correlation between serum D-serine levels and functional promoter polymorphisms of GRIN2A and GRIN2B genes.

GRIN2A GRIN2B

1.37e-052129216266783
Pubmed

Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains.

GRIN2A GRIN2B

1.37e-052129227839871
Pubmed

A receptor-like protein-tyrosine phosphatase PTPzeta/RPTPbeta binds a heparin-binding growth factor midkine. Involvement of arginine 78 of midkine in the high affinity binding to PTPzeta.

MDK PTPRZ1

1.37e-052129210212223
Pubmed

Metaplasticity gated through differential regulation of GluN2A versus GluN2B receptors by Src family kinases.

GRIN2A GRIN2B

1.37e-052129222187052
Pubmed

NR2A and NR2B receptor gene variations modify age at onset in Huntington disease in a sex-specific manner.

GRIN2A GRIN2B

1.37e-052129217569088
Pubmed

Altered effects of ethanol in NR2A(DeltaC/DeltaC) mice expressing C-terminally truncated NR2A subunit of NMDA receptor.

GRIN2A GRIN2B

1.37e-052129211530236
Pubmed

Evolution of NMDA receptor cytoplasmic interaction domains: implications for organisation of synaptic signalling complexes.

GRIN2A GRIN2B

1.37e-052129218197970
Pubmed

Toll-like Receptor (TLR)-induced Rasgef1b expression in macrophages is regulated by NF-κB through its proximal promoter.

RELA RASGEF1B

1.37e-052129232866686
Pubmed

Crybb2 coding for βB2-crystallin affects sensorimotor gating and hippocampal function.

GRIN2A GRIN2B MKI67

1.39e-0513129324096375
Pubmed

Redox regulation of cardiomyocyte cell cycling via an ERK1/2 and c-Myc-dependent activation of cyclin D2 transcription.

MYC MKI67 CDC6

1.39e-0513129325450615
Pubmed

Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.

IPO5 MYO1D RPS5 PSMC2 RPS23 DHX9 SF3B1 CCT8 KPNB1

1.39e-05383129929331416
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KIF23 CTTNBP2 USP28 TRIOBP SIRPB1 GRIN2A GRIN2B MDK SF3B1 EHMT1 CCT8 SMARCC2 WDFY3 KPNB1

1.45e-059631291428671696
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

TUT4 MYO1D TRIOBP DHX57 SMG5 ANKHD1 URB1 MKI67 EHMT1 CCT8 DHX29 VCL

1.72e-057241291236232890
Pubmed

PTENα and PTENβ promote carcinogenesis through WDR5 and H3K4 trimethylation.

IPO5 RPS5 RPS23 DHX9 MKI67 CCT8 KPNB1

1.75e-05217129731685992
Pubmed

The murine ortholog of Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc.

GRIN2A GRIN2B MKI67

1.76e-0514129332249816
Pubmed

BCL7A-containing SWI/SNF/BAF complexes modulate mitochondrial bioenergetics during neural progenitor differentiation.

GRIN2A GRIN2B SMARCC2

1.76e-0514129336305367
InteractionBRCA1 interactions

MYC IPO5 KIF23 RBL2 USP28 RPS5 PSMC2 RELA RPS23 DHX9 GMPS SF3B1 FAM111A BRCA2 SSX2IP TONSL MKI67 CCT8 SLX4IP SMARCC2 SLX4 VCL KPNB1

2.32e-06124912523int:BRCA1
InteractionSLX4 interactions

KIF23 RPS5 KDM3B ANKHD1 DHX9 GMPS SF3B1 BRCA2 MKI67 EHMT1 CCT8 SLX4IP SLX4 ELL KPNB1

2.66e-0657212515int:SLX4
InteractionSPDL1 interactions

MYC IPO5 TUT4 CTTNBP2 RPS5 RPS23 DHX9 SF3B1 CPNE3 SLX4 KPNB1

4.35e-0631512511int:SPDL1
InteractionTERF2IP interactions

MYC KIF23 ARPP21 USP28 KDM3B BRCA2 BANP CPNE3 MKI67 SLX4IP SMARCC2 VGLL4 WDFY3 SLX4

8.56e-0655212514int:TERF2IP
InteractionCCNE1 interactions

MYC RBL2 SF3B1 KLF10 BRCA2 CDC6 KPNB1

1.05e-051211257int:CCNE1
InteractionSIRT7 interactions

IPO5 KIF23 MYO1D RPS5 PSMC2 DHX57 RPS23 ANKHD1 GMPS URB1 SF3B1 MKI67 SMARCC2 UTP20 VCL KPNB1

1.49e-0574412516int:SIRT7
InteractionGSK3B interactions

MYC IPO5 DENND4A PSMC2 TRIOBP RELA GMPS PPARGC1A SF3B1 SSX2IP TONSL CPNE3 MKI67 CCT8 SLX4 VCL KPNB1

2.61e-0586812517int:GSK3B
InteractionACTC1 interactions

MYC KIF23 MYO1D RPS5 KDM3B GRIN2B SF3B1 MKI67 ASPM PAN2 CCT8 SMARCC2 SLX4 VCL KPNB1

2.65e-0569412515int:ACTC1
InteractionCALM1 interactions

MYC UNC13B DENND4A KIF23 ARPP21 MYO1D KDM3B RELA IQCN GRIN2B MYO3A SF3B1 ASPM PAN2

3.46e-0562612514int:CALM1
InteractionRPL35 interactions

MYC IPO5 KIF23 RPS5 PSMC2 RPS23 MDK MST1R SF3B1 FAM111A PAN2 CCT8 KPNB1

4.41e-0555812513int:RPL35
InteractionNPM1 interactions

MYC IPO5 KIF23 RPS5 DHX57 RELA RPS23 MDK DHX9 URB1 FAM111A BRCA2 BANP MKI67 ASPM NFYC PAN2 RP1 DHX29 SLX4

4.88e-05120112520int:NPM1
InteractionREV1 interactions

MYC RELA BRCA2 SLX4

6.36e-05351254int:REV1
InteractionDYNLL1 interactions

MYC CDC42BPG KIF23 CTTNBP2 USP28 RPS5 KMT2C SSX2IP PAN2 TRAF3IP3 ELL MORN3

8.01e-0551012512int:DYNLL1
InteractionCALML3 interactions

MYC UNC13B KIF23 MYO1D KDM3B IQCN FRMD1 MKI67

9.53e-052301258int:CALML3
InteractionTOP3B interactions

UNC13B IPO5 PLXNA3 KIF23 MYO1D KDM3B DHX57 SMG5 MED13L ANKHD1 DHX9 MST1R PLEKHG1 KMT2C URB1 KLF10 SSX2IP BANP EHMT1 WDFY3 ELL GAREM1

9.61e-05147012522int:TOP3B
InteractionRPS6 interactions

MYC KIF23 RPS5 PSMC2 DHX57 RPS23 DHX9 URB1 FAM111A MKI67 PAN2 UTP20 DHX29 SLX4 VCL KPNB1

1.02e-0487412516int:RPS6
InteractionPOLDIP3 interactions

MYC PSMC2 DHX9 MST1R BRCA2 BANP PAN2 SLX4

1.17e-042371258int:POLDIP3
InteractionTP63 interactions

RBL2 USP28 PIWIL1 RELA DHX9 BRCA2 ASPM CCT8 VCL

1.19e-043041259int:TP63
InteractionSLFN11 interactions

MYO1D DHX57 DHX9 SF3B1 MKI67 CCT8 SMARCC2 DHX29 VCL KPNB1

1.20e-0437612510int:SLFN11
InteractionNCL interactions

MYC KIF23 RPS5 PSMC2 RPS23 MDK FAM90A27P DHX9 ENAM PPARGC1A BRCA2 PTPRZ1 PAN2 SLX4 KPNB1

1.28e-0479812515int:NCL
InteractionAR interactions

MYC CDC42BPG MYO1D USP28 RPS5 KDM3B PSMC2 RELA RPS23 MED13L DHX9 GMPS KMT2C SF3B1 TONSL CPNE3 SMARCC2

1.35e-0499212517int:AR
InteractionRAD21 interactions

MYC CTTNBP2 RPS5 PSMC2 PKD1L2 DHX9 BRCA2 CCT8 SLX4 KPNB1

1.42e-0438412510int:RAD21
InteractionNSMCE2 interactions

MYC USP28 PAN2 SLX4

1.44e-04431254int:NSMCE2
InteractionKCTD7 interactions

IPO5 ZNF587 CPNE3 ZNF417 KPNB1

1.49e-04811255int:KCTD7
InteractionYTHDF3 interactions

MYC KIF23 TUT4 DHX57 SMG5 ANKHD1 MKI67 PAN2

1.52e-042461258int:YTHDF3
InteractionTMOD2 interactions

MYC MYO1D DHX9 PLEKHG1 PAN2

1.58e-04821255int:TMOD2
InteractionZBTB7A interactions

RELA DHX9 SF3B1 MKI67 SMARCC2 UTP20

1.68e-041311256int:ZBTB7A
InteractionRPL19 interactions

MYC KIF23 RPS5 DHX57 RPS23 DHX9 GMPS MST1R SF3B1 FAM111A MKI67 PAN2 SLX4

1.69e-0463812513int:RPL19
InteractionFBL interactions

MYC IPO5 KIF23 TUT4 RPS5 DHX57 RPS23 URB1 MKI67 PAN2 UTP20 DHX29 SLX4

1.72e-0463912513int:FBL
InteractionCXXC1 interactions

MYC RELA MDK KMT2C MKI67 NFYC

1.75e-041321256int:CXXC1
InteractionCEBPB interactions

MYC IPO5 PNKP RPS5 KDM3B PSMC2 RELA RPS23 ANKHD1 DHX9 GMPS SF3B1 BRCA2 MKI67 ASPM NFYC EHMT1 CCT8 SMARCC2 ELL KPNB1

2.08e-04144312521int:CEBPB
GeneFamilyDEAH-box helicases

DHX57 DHX9 DHX29

7.49e-0516953500
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN2A GRIN2B

5.64e-0479521201
GeneFamilyPlexins

PLXNA3 PLXNC1

9.60e-049952683
GeneFamilyT cell receptor beta locus at 7q34

TRBV29-1 TRBV5-8 TRBV5-5 TRBV5-3

1.14e-0387954372
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

MYO1D ZFYVE16 MKI67 HYDIN ELL

2.67e-03181955694
GeneFamilyActins|Deafness associated genes

TRIOBP TECTA MYO3A ELMOD3

2.98e-031139541152
GeneFamilyArmadillo repeat containing|Importins

IPO5 KPNB1

3.96e-0318952596
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

MYC KIF23 TUT4 ZFYVE16 KDM3B MED13L CBLB GMPS KLF10 BRCA2 SOCS5 NFYC UTP20 N4BP1 WDFY3 VCL

4.48e-0685612816M4500
CoexpressionGSE3982_DC_VS_MAC_DN

UNC13B MYO1D ITGA8 ZNRF4 TLR8 PIK3CG MKI67 BAIAP3

6.53e-062001288M5460
CoexpressionREICHERT_MITOSIS_LIN9_TARGETS

KIF23 LMLN MKI67 ASPM

8.73e-06271284M2483
CoexpressionREICHERT_MITOSIS_LIN9_TARGETS

KIF23 LMLN MKI67 ASPM

1.01e-05281284MM1323
CoexpressionGSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP

PNKP KIF23 RBL2 MTMR10 URB1 BRCA2 SLX4

3.12e-051811287M6857
ToppCelldroplet-Spleen-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC25A21 CTTNBP2 RTL4 SSX2IP MKI67 ASPM CDC6 GAREM1

7.46e-0818812881a3f95b4fd7611c634666761ddf21f1e58e56af8
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / Treatment groups by lineage, cell group, cell type

KIF23 DHX57 BRCA2 ZNF587 MKI67 ASPM RP1 CDC6

1.07e-071971288038fd92750257d43d5e980fd06d77742b543f11a
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF23 MDK MYO3A BRCA2 MKI67 ASPM CDC6

7.31e-07174128746cbb462173a684ceb9e680f9259dc3b133763f7
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

UNC13B KIF23 MYO3A PTPRZ1 MKI67 ASPM CDH3

1.36e-06191128739220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B KIF23 PLEKHG1 MYO3A PTPRZ1 ASPM CDH3

1.41e-06192128725378b5e4b0cea8415ff125783511fc25a56fc00
ToppCell(7)_Epithelial_cells-(7)_Epithelial-J_(AT1-AT2_progenitors)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

KIF23 MYO3A FAM111A BRCA2 MKI67 ASPM CDC6

1.51e-0619412874d6ae2b25db11a4ae6dadee83be5c8c05b1225c3
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

KIF23 PSMC2 GMPS MKI67 ASPM CCT8 CDC6

1.73e-061981287880f9817f5145f10f29fc05c5866090433532fe2
ToppCellproximal-Epithelial-Proliferating_Basal|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KIF23 MYO3A BRCA2 MKI67 ASPM CDC6 CDH3

1.79e-061991287521ff4ae3437c8ba477a0a42b9da195af976c3ff
ToppCellproximal-Epithelial-Proliferating_Basal-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KIF23 MYO3A BRCA2 MKI67 ASPM CDC6 CDH3

1.79e-061991287e8549b2c4152cb23548351d9cee27c3805892cd8
ToppCellproximal-3-Epithelial-Proliferating_Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KIF23 MYO3A BRCA2 MKI67 ASPM CDC6 CDH3

1.79e-0619912872263bb73d9c5693b44d91d2548305efc1b6e4079
ToppCellBiopsy_Other_PF-Epithelial-Proliferating_Epithelial_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

KIF23 MYO3A PTPRZ1 TONSL MKI67 ASPM CDC6

1.79e-061991287d73667e2e93026d95184e24ff0bc90afd1fb74a9
ToppCellNon-neuronal|World / Primary Cells by Cluster

KIF23 MDK FAM111A BRCA2 PTPRZ1 MKI67 ASPM

1.79e-061991287165d9de6cedc79e13bb6fa244e8898a5dacc54ff
ToppCellBiopsy_IPF-Epithelial-Proliferating_Epithelial_cells|Biopsy_IPF / Sample group, Lineage and Cell type

KIF23 BRCA2 TONSL MKI67 ASPM CDC6 CDH3

1.85e-06200128763c5402f050fdb12abab3c8b7f33d4914ae26b9b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO3A BRCA2 TONSL MKI67 ASPM CDC6

6.26e-0615712861ccb07a38d3fb606ee5fbc0437655f49baaaa62c
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTTNBP2 MROH2A GRIN2B TECTA PTPRZ1 HYDIN

6.98e-061601286c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTTNBP2 MROH2A GRIN2B TECTA PTPRZ1 HYDIN

6.98e-06160128625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 MROH2A PPARGC1A RASGEF1B HYDIN MORN3

8.32e-061651286936581de8fcd097401707438b9bbe89dd4e3e247
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF23 MYO3A FAM111A BRCA2 MKI67 ASPM

9.23e-061681286d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 FAM111A CSF2RA MKI67 ASPM SLX4

9.23e-06168128652fd65024af8683db11d931f7563cbe8eb815d1c
ToppCellDividing_Macrophages-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

KIF23 PIWIL1 FAM111A BRCA2 MKI67 ASPM

9.54e-061691286bc859a103cad567caf50c3c3882d2d2017807c73
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GCNA KIF23 PIK3CG MKI67 ASPM CDC6

1.02e-051711286e3cab55f39879e2bd3e8bda91802181075839bc4
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GCNA KIF23 PIK3CG MKI67 ASPM CDC6

1.02e-05171128652fdc2a4ec36fb91583b1215362548ceb6740ae1
ToppCell368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

KIF23 EDN1 MKI67 ASPM CDC6 SLX4

1.24e-051771286844017225e9039d1bc621a9630a30c2e9a51b36d
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PNKP KIF23 CPNE3 MKI67 ASPM VCL

1.28e-05178128615a99080e9f669572ab6d82934f324e6714846c1
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PNKP KIF23 CPNE3 MKI67 ASPM VCL

1.28e-051781286200308e109abb7e6f8816a6f8cce6d56862d4098
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 MYO1D MTMR10 NTN4 HYDIN SLX4

1.28e-051781286c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SANBR MYO3A BRCA2 TONSL MKI67 CDC6

1.32e-05179128688d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF23 MYO3A BRCA2 MKI67 ASPM CDC6

1.37e-051801286f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

1.41e-05181128673b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCellIIF-Lymphocyte-T_NK-T_NK_proliferative|IIF / Disease, Lineage and Cell Type

KIF23 MST1R BRCA2 MKI67 ASPM CDC6

1.55e-051841286ab8b45ce40e8c5f66e5c23332a591b4f9cba4ce1
ToppCellPBMC-Mild-cDC_12|Mild / Compartment, Disease Groups and Clusters

IPO5 MKI67 ASPM UTP20 CDC6 KPNB1

1.80e-051891286946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCelldroplet-Marrow-nan-3m-Hematologic-erythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC25A21 BRCA2 SSX2IP MKI67 ASPM CDC6

1.80e-0518912868a38baee58a27c2fa3f4bd131ab9f15723ed9295
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF23 SIRPB1 FAM111A BRCA2 MKI67 ASPM

1.91e-051911286b85a0978dc1e8af4f49423f56dcfd52efce09ed1
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

FAM111A CSF2RA BRCA2 FMN1 MKI67 ASPM

1.97e-051921286a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellCV-Healthy-2|Healthy / Virus stimulation, Condition and Cluster

MYC KIF23 MKI67 ASPM UTP20 CDC6

1.97e-051921286a249787f7e2f50af49bd7d4752c411a067a5e3d3
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-Cycling_T|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KIF23 TRBV29-1 BRCA2 MKI67 ASPM TRAF3IP3

2.03e-051931286bec113472c40c0106a9427248cbcf54548797596
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.03e-051931286e45ce9cf8421512b57f157c24b64793b47b4ba4b
ToppCellwk_20-22-Hematologic_Lymphocytic-B-Pro-B|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

KIF23 ARPP21 BRCA2 MKI67 ASPM CDC6

2.09e-0519412863590ff471f74a361ee5bf02a58e3104cd3bf7d00
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|367C / Donor, Lineage, Cell class and subclass (all cells)

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.09e-051941286a12b64945e10f00aa983678a02586c59badc1570
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

UNC13B RASSF10 NTN4 PTPRZ1 FMN1 CDH3

2.09e-051941286c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasmablast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARPP21 ENAM BRCA2 PLXNC1 PIK3CG ZNF778

2.15e-051951286c6e31038be2463f1601d52c82efa4e9facb8228f
ToppCellHealthy/Control-T/NK_proliferative|Healthy/Control / Disease group and Cell class

KIF23 BRCA2 MKI67 ASPM CDC6 HYDIN

2.15e-051951286957458fdc39723f4a31bd7fd3ce32891aa3fd462
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.21e-0519612869591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

KIF23 TRIOBP FAM111A BRCA2 MKI67 ASPM

2.21e-0519612865905f0e3061a6b98b7a33d64c782c3dda2cd51ef
ToppCellsevere-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CYP51A1 KMT2C BRCA2 CPNE3 MKI67 ASPM

2.27e-05197128670704b149b2820b8601d2495b7cd9cbe91eda262
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MYO3A PTPRZ1 MKI67 ASPM CDC6 CDH3

2.27e-05197128625bbe270d0897b9b1bd00d205f66efd1def81b99
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KIF23 MYO3A BRCA2 MKI67 ASPM CDC6

2.34e-051981286f088badb90c6c2d916195f5649eda102119c9ac6
ToppCellNon-neuronal-Dividing-Radial_Glia-vRG-11|World / Primary Cells by Cluster

KIF23 MDK BRCA2 MKI67 ASPM CDC6

2.34e-051981286672c6faeed54e1397e12c0aac1a5cbd19c684f06
ToppCellCOVID-19-Lymphoid-Proliferating_CD4_T_cells|Lymphoid / Condition, Lineage and Cell class

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.41e-0519912862e9ee10a069afca5dbd9f0863cf90a66db1a6ffb
ToppCellBiopsy_Control_(H.)-Epithelial-Proliferating_Epithelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

KIF23 MYO3A BRCA2 MKI67 ASPM CDC6

2.41e-0519912864fcf5bec207e4384fd73c5e8801a7e414e3ee7b0
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.41e-05199128688d130e2451e61afb710edf552e6b346b9fcfb2b
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Polychromatic_Erythroblast|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

SLC25A21 KIF23 BRCA2 MKI67 ASPM CDC6

2.41e-051991286fa698f00d2dad74d28b4696c8c23dce70f123e52
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

DYM MYO1D MED13L KMT2C RASGEF1B WDFY3

2.41e-05199128694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Basophilic_Erythroblast|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

MYC IPO5 GMPS PLXNC1 CCT8 KPNB1

2.41e-0519912866f159c1215439ec22374903124085746fa8da333
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Dividing_Basal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KIF23 MYO3A PTPRZ1 MKI67 ASPM CDH3

2.41e-051991286f0c289523957258d16135c04679db379d43d28d9
ToppCellNon-neuronal-Dividing|World / Primary Cells by Cluster

KIF23 MDK FAM111A BRCA2 MKI67 ASPM

2.47e-05200128650fa7b34a05f2c5ebbc7d113bd8e31326688a231
ToppCelldistal-Hematologic-Proliferating_Macrophage|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.47e-0520012863835a8a9739b8cd5bf19c40765ef76907ac1ad38
ToppCellmild-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SIRPB1 MED13L CSF2RA KLF10 RASGEF1B WDFY3

2.47e-052001286934c2efc780318c66d667ca75be0de350361d351
ToppCell356C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

KIF23 FAM111A MKI67 ASPM CDC6 KPNB1

2.47e-052001286548a0f486ab8745da107f2815914dbf873a6e3c8
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Proliferating|3_mon / Sample Type, Dataset, Time_group, and Cell type.

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.47e-0520012869279415f5e76cb5b4e071c6582ac249b72dd694c
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_ventral_progenitors|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.47e-0520012869359faa749f41aaef70b4874f20b4eed2dc12cc2
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells-Neuroepithelial_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.47e-052001286203b9a5de4430713da01b3331e69381db449a3a0
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Proliferating-Cycling|3_mon / Sample Type, Dataset, Time_group, and Cell type.

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.47e-052001286d582385b2dbb25eeba1b22c5d258a8f26a40ef8b
ToppCellNon-neuronal-Dividing-IPC-IPC-div2|World / Primary Cells by Cluster

MDK FAM111A BRCA2 MKI67 ASPM CDC6

2.47e-0520012864923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells|GW26 / Sample Type, Dataset, Time_group, and Cell type.

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.47e-052001286a854e19703dc920e48304541e2b06ed013292f3e
ToppCellsevere-T/NK_proliferative|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KIF23 GMPS BRCA2 MKI67 ASPM CDC6

2.47e-052001286d341f4e500377a5bef82c24bf64704b981053336
ToppCelldistal-Hematologic-Proliferating_Macrophage-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.47e-0520012869c03a8da12d29618f72c429836c1d1bd84a78b12
ToppCellLAM-Myeloid-pMacrophage|LAM / Condition, Lineage and Cell class

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.47e-0520012867e233d037165c9d3607604aaaf0f368e266567d3
ToppCellBiopsy_Other_PF-Immune-Proliferating_Macrophages|Biopsy_Other_PF / Sample group, Lineage and Cell type

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.47e-05200128661473e8613f39a92002d5b631e6bd563735566e4
ToppCellNon-neuronal-Dividing-IPC-IPC-div2-5|World / Primary Cells by Cluster

MDK FAM111A BRCA2 MKI67 ASPM CDC6

2.47e-052001286dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCellNon-neuronal-Dividing-Radial_Glia-vRG|World / Primary Cells by Cluster

KIF23 MDK FAM111A BRCA2 MKI67 ASPM

2.47e-0520012867596143925cd403ec7baceef87d19d570e48586a
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KIF23 MYO3A BRCA2 MKI67 ASPM CDC6

2.47e-052001286af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCellNon-neuronal-Dividing-Radial_Glia-vRG-17|World / Primary Cells by Cluster

KIF23 MDK FAM111A BRCA2 MKI67 ASPM

2.47e-0520012864417f14d45ce683c1a45ec989ae63ee6c047353e
ToppCellNon-neuronal-Dividing-Radial_Glia|World / Primary Cells by Cluster

KIF23 MDK FAM111A BRCA2 MKI67 ASPM

2.47e-052001286ecbbad00e16041a9e1cd88d8bd7279a1b52c0aa4
ToppCelldistal-3-Hematologic-Proliferating_Macrophage|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.47e-0520012861b65c97e8123d0572d31525d6a10bc7f16857959
ToppCell(3)_MNP-(3)_DC_Monocyte_Dividing|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.47e-052001286d94fe9bd6ee7c1fed14666f24de41bda014e299b
ToppCell356C-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KIF23 FAM111A BRCA2 MKI67 ASPM CDC6

2.47e-0520012865b014c658eecc5e73679e5feb7a2aaa3d297001d
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF23 BRCA2 MKI67 ASPM CDC6

4.29e-0513412854d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCellEndothelial-Endothelial-H_(cycle)|Endothelial / shred on cell class and cell subclass (v4)

KIF23 URB1 MKI67 ASPM VGLL4

4.93e-051381285a1f41a5a9da40adcc343722baef78c603599c3f0
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DENND4A KIF23 FAM111A MKI67 ASPM

6.45e-05146128545d7cb73776e60d22f335a651845e21e16948fcc
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF23 PIWIL1 BRCA2 MKI67 ASPM

1.08e-0416312855285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFYVE16 FMN1 DHX29 SLX4 KPNB1

1.08e-041631285132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SMG5 BRCA2 MKI67 N4BP1 VGLL4

1.12e-0416412854ef776d1bab4103d42d3a4f22cdfb49e8d2bc5a0
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARPP21 MDK MKI67 ASPM C8A

1.15e-0416512850ae39c9a6d1265d65dc0660924612cfe11e489ec
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARPP21 MDK MKI67 ASPM C8A

1.15e-041651285686cf89077cc7b744a6127de2b34d8c27da8b6c4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO3A BRCA2 TONSL MKI67 CDC6

1.15e-04165128588681101d7cf60b99b8ace5d8c0944323b937306
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARPP21 MDK MKI67 ASPM C8A

1.15e-041651285a5ed8c331d5551cd8bce50bdc31cb893218317cd
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l34|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DENND4A TLR8 CSF2RA PIK3CG MKI67

1.25e-04168128584977db9d71e59208727885320cc18d80d064380
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

KIF23 MYO3A BRCA2 MKI67 CDC6

1.28e-041691285a949f547b53126a208819bade74a1ac9b2a36ea7
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 ITGA8 MDK MKI67 ASPM

1.28e-041691285563c267edaade0e5df192ad953801ef9768d4270
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF23 PIWIL1 BRCA2 MKI67 ASPM

1.28e-041691285e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SANBR MYO3A BRCA2 MKI67 CDC6

1.28e-041691285121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

KIF23 MYO3A BRCA2 MKI67 CDC6

1.28e-041691285195d5cd60d646ac6d40a3321b2f739917e7aef14
ToppCellCiliated_cells-A-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

ARPP21 GPR179 C2CD4D RP1 HYDIN

1.32e-0417012858b7ef1464ea589886b575ebad5447b085cbdcdba
ToppCellsystemic_lupus_erythematosus-treated-Hematopoietic-Progen-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

MYC TUT4 RBL2 RPS5 TRAF3IP3

1.36e-04171128561d622153b91702ef21b0efc7b9581e592b7ccea
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF23 FAM111A CSF2RA MKI67 ASPM

1.36e-04171128505014cf6746e6663e376fdd681f1b43a7081c603
ToppCellsystemic_lupus_erythematosus-treated-Hematopoietic-Progen|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

MYC TUT4 RBL2 RPS5 TRAF3IP3

1.36e-04171128509b3fa120f63c411f8a0dd6bd230a9720ce83fb1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TECTA PIK3CG MKI67 ASPM CDC6

1.36e-041711285c2dbc439af28d4fabb24d57685b75b2e588819b0
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF23 FAM111A CSF2RA MKI67 ASPM

1.36e-041711285d6114db2292fbb27b39d090d51fd305a135b1ccf
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IPO5 DENND4A PNKP KIF23 CDC6

1.43e-04173128528c98a9a54aa2cfa67464db4f628c9357ad185b9
DrugSulfur Dioxide

MYC RELA GRIN2A GRIN2B EDN1 PPARGC1A

7.42e-07581246ctd:D013458
Diseaseplacental insufficiency (biomarker_via_orthology)

GRIN2A GRIN2B PPARGC1A

3.90e-0681233DOID:3891 (biomarker_via_orthology)
DiseaseChildhood Medulloblastoma

MYC BRCA2 PIK3CG EHMT1

3.13e-05431234C0278510
DiseaseMelanotic medulloblastoma

MYC BRCA2 PIK3CG EHMT1

3.13e-05431234C1275668
DiseaseMedullomyoblastoma

MYC BRCA2 PIK3CG EHMT1

3.13e-05431234C0205833
DiseaseDesmoplastic Medulloblastoma

MYC BRCA2 PIK3CG EHMT1

3.13e-05431234C0751291
DiseaseAdult Medulloblastoma

MYC BRCA2 PIK3CG EHMT1

3.13e-05431234C0278876
Diseaseleiomyoma (implicated_via_orthology)

MYC MKI67

5.16e-0531232DOID:127 (implicated_via_orthology)
DiseaseMedulloblastoma

MYC BRCA2 PIK3CG EHMT1

5.71e-05501234C0025149
Diseaseskin hydration measurement

MYC PIWIL1 PLEKHG1

8.90e-05211233EFO_0009586
Diseasemethylmalonate (MMA) measurement

ACSF3 ZNF778

1.03e-0441232EFO_0800622
DiseaseHuntington's disease (is_implicated_in)

GRIN2A GRIN2B PPARGC1A

1.18e-04231233DOID:12858 (is_implicated_in)
Diseasecancer (implicated_via_orthology)

MYC IPO5 RBL2 PSMC2 FRMD1 BRCA2 SMARCC2

1.37e-042681237DOID:162 (implicated_via_orthology)
DiseaseMYELODYSPLASTIC SYNDROME

MYC SF3B1 BRCA2 SLX4

1.80e-04671234C3463824
Diseaseovarian neoplasm

MYC RBL2 ITGA8 BRCA2 MKI67

2.52e-041341235C0919267
DiseaseMalignant neoplasm of ovary

MYC RBL2 ITGA8 BRCA2 MKI67

2.79e-041371235C1140680
Diseaseductal carcinoma in situ (is_implicated_in)

RELA BRCA2

3.57e-0471232DOID:0060074 (is_implicated_in)
Diseasecognitive disorder (biomarker_via_orthology)

GRIN2A GRIN2B

4.75e-0481232DOID:1561 (biomarker_via_orthology)
DiseaseNeurodevelopmental Disorders

GRIN2B MED13L KMT2C WDFY3

6.30e-04931234C1535926
DiseaseLeukemia, Myelocytic, Acute

MYC CBLB KMT2C SF3B1 SLX4

8.09e-041731235C0023467
Diseasediabetic retinopathy (biomarker_via_orthology)

EDN1 PPARGC1A PIK3CG

8.83e-04451233DOID:8947 (biomarker_via_orthology)
Diseasehyperhomocysteinemia (implicated_via_orthology)

GRIN2A GRIN2B

9.25e-04111232DOID:9279 (implicated_via_orthology)
Diseasevascular dementia (is_marker_for)

GRIN2A GRIN2B

9.25e-04111232DOID:8725 (is_marker_for)
Diseaseunipolar depression, multiple sclerosis

TDRD15 RASSF10

1.11e-03121232EFO_0003761, MONDO_0005301
DiseaseSchizophrenia

IPO5 DYM ITGA8 RELA SIRPB1 GRIN2A GRIN2B MDK PPARGC1A CSF2RA PTPRZ1

1.19e-0388312311C0036341
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

TRIOBP TECTA MYO3A

1.27e-03511233cv:CN043650
DiseaseFanconi anemia

BRCA2 SLX4

1.52e-03141232cv:C0015625
Diseaseautosomal dominant polycystic kidney disease (is_marker_for)

ITGA8 EDN1

1.52e-03141232DOID:898 (is_marker_for)
DiseaseChronic Lymphocytic Leukemia

MYC RBL2 SF3B1

1.58e-03551233C0023434
DiseaseHypertrophic Cardiomyopathy

MYC KLF10 VCL

1.76e-03571233C0007194
Diseaseage-related hearing impairment

PIWIL1 PSMC2 TRIOBP MED13L M1AP FMN1

2.43e-033241236EFO_0005782
DiseaseBone marrow hypocellularity

BRCA2 SLX4

2.52e-03181232C1855710
Diseaselow density lipoprotein cholesterol measurement, physical activity

TDRD15 RP1 KPNB1

2.67e-03661233EFO_0003940, EFO_0004611
DiseaseColorectal Carcinoma

MYC UNC13B MYOT GRIN2A ITPRID1 KMT2C MKI67 PAN2 TRAF3IP3

2.76e-037021239C0009402
Diseaseevent free survival time, urinary bladder cancer

GRIN2B TFF1

2.81e-03191232EFO_0000482, MONDO_0001187
Diseaseascending aortic diameter

MED13L EDN1 SLX4IP HYDIN

2.85e-031401234EFO_0021787
Diseasebipolar I disorder

TDRD15 KDM3B GRIN2A ANKHD1

2.92e-031411234EFO_0009963
DiseaseAdenocarcinoma of prostate

MYC BRCA2

3.12e-03201232C0007112
Diseaseestrogen-receptor negative breast cancer

BRCA2 ELL GAREM1

3.29e-03711233EFO_1000650
Diseaseepilepsy (biomarker_via_orthology)

RELA GRIN2B

3.44e-03211232DOID:1826 (biomarker_via_orthology)
DiseaseLewy Body Disease

EDN1 PPARGC1A

3.77e-03221232C0752347
DiseaseAcute Lung Injury

EDN1 TFF1

3.77e-03221232C0242488
DiseaseNonsyndromic genetic hearing loss

TRIOBP TECTA MYO3A

3.98e-03761233cv:C5680182
Diseaseautism spectrum disorder symptom

ITGA8 SSX2IP

4.12e-03231232EFO_0005426
Diseasespermatogenic failure (is_implicated_in)

GCNA IQCN

4.12e-03231232DOID:0111910 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
RQRLEINCQDPSIKT

BANP

41

Q8N9N5
SQLETSLKRLQCPQV

AKR7A2

121

O43488
RVLVRKLCQPQSTGS

ELL

286

P55199
SRECNRQQKVIPVVN

ELMOD3

271

Q96FG2
VRSQLETSLKRLQCP

AKR7L

91

Q8NHP1
IFVTKRNREVCTNPN

CCL16

66

O15467
QRVRRAATPAAVTCQ

C8A

26

P07357
DIKSSVLRQVQVCPS

BAIAP3

41

O94812
CETVREQLTNSIRKQ

SSX2IP

331

Q9Y2D8
ERTERIKNCLNPQFS

CPNE3

46

O75131
QVRIVSENPQREACS

ACSF3

386

Q4G176
PQQRVTGAICVNSKE

ANGPTL2

61

Q9UKU9
QTCQNKAQVRSTRPQ

APEX2

366

Q9UBZ4
VCTQPRRISAVSLAN

DHX29

626

Q7Z478
VSQKVDRVRSPLQAC

ASPM

181

Q8IZT6
INKTSSTRIPEQRFC

ARPP21

221

Q9UBL0
CTRSIQIPANRSKTA

DENND4A

1561

Q7Z401
KLNRRRQQQTPSSCS

RASSF10

186

A6NK89
RNVCVQTDRETFLKP

FMN1

801

Q68DA7
RQTCPATITAKNRPQ

IQCN

416

Q9H0B3
QVGECRRVQQLTLSP

CDC42BPG

1126

Q6DT37
QILRTCSRDPTQAIA

RBL2

446

Q08999
VVKTRFQIQRCATDP

SLC25A21

36

Q9BQT8
TCEKYQPTIQTRNIR

PAN2

721

Q504Q3
SQKASCRISQRRNLP

NSUN3

226

Q9H649
RKERSPQQNIVSCVS

KMT2C

196

Q8NEZ4
LETCVVNIALPNRSR

MED13L

1851

Q71F56
PCKTGQLQTNRARAT

M1AP

476

Q8TC57
SKQNIRRDCNPEVSE

ITPRID1

261

Q6ZRS4
QKLSQQQESVCPRES

GPR179

1526

Q6PRD1
QRICNAITKSHPQRS

MTMR10

311

Q9NXD2
RYNAQCQETIRVTKP

MDK

111

P21741
PLQLTCRQDQRAVAV

LMLN

426

Q96KR4
NVRKCTDRQNSPVTS

CBLB

466

Q13191
RPQQVRKQCGQDSRT

FAM90A27P

266

A6NNH2
LSKCVQVRVRPNNVS

PLXNA3

536

P51805
SSRELCQNKSQPNRT

PLXNC1

541

O60486
QPLTRSLSEKNRCDQ

GAREM1

466

Q9H706
CISRQNKSVLRPAVT

KDM3B

1126

Q7LBC6
PNNCSGVRKRRLSNV

PRKD3

201

O94806
VLCSVQSPRKVLQEV

METTL7B

146

Q6UX53
RRQCIRENGNVAKTP

MKI67

831

P46013
QCNREKNRTSSIIPV

PTPRZ1

2046

P23471
PCAKRLANVVRQVQT

IPO5

1056

O00410
KPQSIQRDIITVCND

RASGEF1B

191

Q0VAM2
CRQIPFDTTNNRKIR

ITGA8

106

P53708
PRRCLKETLQITQTE

NFYC

286

Q13952
RQVRVQESSCPLAQQ

PKD1L2

2031

Q7Z442
PCSTRKQLQDQEIRA

PPARGC1A

446

Q9UBK2
SQKKLRTRTISNCPN

PLA2G4E

101

Q3MJ16
SQATRQEPCTQVRTR

FRMD1

446

Q8N878
ITCDVNIVVRPISNK

HYDIN

3391

Q4G0P3
QKQPSCQRSVVIRTF

GMPS

626

P49915
TCVPFRTTKERQEIQ

BRCA2

2331

P51587
SNQQIRQTCVRKSLI

CABP7

176

Q86V35
ATISVCRSLVENNPR

DYM

56

Q7RTS9
PRSKVTQCSQNTKRS

CTTNBP2

1616

Q8WZ74
EKVANIICTQPRRIS

DHX57

591

Q6P158
NPESEKRNTCVLREQ

FAM111A

281

Q96PZ2
QVCVSPTVNQRLKDS

CYP51A1

406

Q16850
REQQSRVVKCSANPI

C2CD4D

271

B7Z1M9
QPSQCRFQTLRLPTK

MTFMT

361

Q96DP5
KSQEITTNSEQRCPL

CDC6

126

Q99741
TQCPDTRVRVAALQN

KPNB1

226

Q14974
SPNRSKCERNTVADV

KLF10

206

Q13118
APKRQASCILNVQSR

GCNA

41

Q96QF7
TLRRNTPCSIKNQLG

ENAM

951

Q9NRM1
NLLPTKATDRENRCQ

EDN1

96

P05305
TPKSREITTLANNQC

EHMT1

526

Q9H9B1
CNQSPVRQVLNITDK

CDH3

556

P22223
KQAENICRQATIQPR

CNTD1

86

Q8N815
KNRVVEPRLSNNECS

CSF2RA

66

P15509
AECNIVVTQPRRISA

DHX9

436

Q08211
TLSLPDQQTGKCRRV

MORN3

76

Q6PF18
ARRRQQEPGQSKTCI

KIF23

746

Q02241
QEPGQSKTCIVSDRR

KIF23

751

Q02241
NIQSVPKCSENERTQ

RP1

1216

P56715
RCLQVPEISTQRKVN

MROH2A

86

A6NES4
TPSQCVVARTLGKQQ

PIWIL1

581

Q96J94
LTPAKRARQQETQLC

RTL4

266

Q6ZR62
TLQSEQPLQVARCTK

PSMC2

86

P35998
FRKAQCPIVERLTNS

RPS5

61

P46782
QSEPARVQCRQVFLK

UTP20

2256

O75691
KLRNRVVPGCVTQSQ

PRLHR

251

P49683
RTNPDLIIVCAQSSQ

SMG5

666

Q9UPR3
SRRNQNCATEIPQIV

SOCS5

76

O75159
CNTKLLSNEIRNIPR

TDRD15

1621

B5MCY1
ITNLRVQLLKRQSCP

NTN4

221

Q9HB63
RVLRQISNNRKCTSP

MYC

331

P01106
GPLTQVTDRKCSRTQ

PNKP

36

Q96T60
TRQPKKQVSSPCAQR

SANBR

591

Q6NSI8
TIEKSLVQNNCLSRP

SMARCC2

126

Q8TAQ2
SQRLCQPSSQEPAKR

URB1

1896

O60287
RTCIQQNIPRSSSTQ

TRIOBP

816

Q9H2D6
SPRVAKTQQKRRNCS

SLX4IP

286

Q5VYV7
TPIRGSCTTQRKLQE

SLX4

1476

Q8IY92
PVRAENQVNVTCQVR

SIRPB1

261

Q5TFQ8
AQTETCTVAPRERQN

TFF1

26

P04155
QLCVTNTRTPSSVRK

ANKHD1

1946

Q8IWZ3
ERQQNRPSVITCASA

VGLL4

156

Q14135
IKTRGQQATLRCSPI

TRBV5-8

31

A0A5A2
QQVLCQRRTSPKPFT

PIK3CG

391

P48736
FPKRETVCLLSQNQV

TECTA

706

O75443
QPNSAIRKCVRVQLI

RPS23

61

P62266
IKTRGQQVTLRCSPI

TRBV5-5

31

A0A597
RPNVTTCRQVGKTLR

TRAF3IP3

36

Q9Y228
IAECSNRRLQEVPQT

TLR8

46

Q9NR97
STPNVVSQQACTRDR

ZNF778

181

Q96MU6
NLQVSVPVISCRSKQ

WDFY3

1791

Q8IZQ1
LKVQERQNRVCTTVA

SF3B1

1101

O75533
SQKRPRCSATAQRVA

TONSL

756

Q96HA7
PCKQRISVQRESQSR

ZNF587

66

Q96SQ5
RRPVKTSTCQKAQVR

ZNRF4

286

Q8WWF5
RTNLLQVCERIPTIS

VCL

1046

P18206
PCKQRISVQRESQSR

ZNF417

66

Q8TAU3
REETRNLTPKQCAVL

UNC13B

1341

O14795
PQNVLENCRSHTEKR

USP28

196

Q96RU2
SAVISQKPSRDICQR

TRBV29-1

16

A0A5B7
SVQRCSVVVSQPNKE

PLEKHG1

1141

Q9ULL1
ECPEVKLARQRNSSV

TUT4

1371

Q5TAX3
RNIQACKELAQTTRT

CCT8

31

P50990
NRAPNTAELKICRVN

RELA

186

Q04206
QNRIQCAIKSLSRIT

MST1R

1106

Q04912
IKTRGQQVTLRCSPI

TRBV5-3

31

A0A0A0MS03
QRTSLLPKDQECVNS

ZFYVE16

51

Q7Z3T8
KCTVSVETRLNQPQP

MYO1D

976

O94832
KPINRRVSSQQCLSG

MYO3A

1466

Q8NEV4
SNCRINTFRTVPIEQ

N4BP1

456

O75113
KQSSIIIQPRQCTEQ

MYOT

36

Q9UBF9
IIQPRQCTEQRFSAS

MYOT

41

Q9UBF9
RNTVPCRKFVKINNS

GRIN2A

431

Q12879
RNTVPCQKRIVTENK

GRIN2B

431

Q13224