Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase binding	RRAGD GCC2 TRIOBP DENND5A RRAGC EVI5L RAB11FIP3	1.82e-04	360	66	7	GO:0051020
GeneOntologyMolecularFunction	protein-glutamic acid ligase activity	TTLL9 TTLL7	4.76e-04	10	66	2	GO:0070739
GeneOntologyMolecularFunction	tubulin-glutamic acid ligase activity	TTLL9 TTLL7	4.76e-04	10	66	2	GO:0070740
GeneOntologyMolecularFunction	calcium ion binding	STIM1 TCHH DST RPTN ITSN1 NUCB1 ACTN1 RAB44 RAB11FIP3	7.65e-04	749	66	9	GO:0005509
GeneOntologyMolecularFunction	cytoskeletal protein binding	STIM1 EZR PTPN3 DST TTLL9 TRIOBP ACTN1 JAKMIP3 SPATA31C1 PXK TTLL7	8.83e-04	1099	66	11	GO:0008092
GeneOntologyCellularComponent	microtubule organizing center	EZR ODF2L RRAGD TTLL9 CEP85L FBF1 MAMLD1 RASSF10 TRIOBP DZIP1 PXK TTLL7 CEP55 RAB11FIP3	6.87e-07	919	65	14	GO:0005815
GeneOntologyCellularComponent	centrosome	ODF2L RRAGD CEP85L FBF1 MAMLD1 RASSF10 TRIOBP DZIP1 PXK CEP55 RAB11FIP3	2.30e-05	770	65	11	GO:0005813
GeneOntologyCellularComponent	ciliary basal body	EZR ODF2L TTLL9 FBF1 DZIP1 TTLL7	3.19e-05	195	65	6	GO:0036064
GeneOntologyCellularComponent	Gtr1-Gtr2 GTPase complex	RRAGD RRAGC	5.69e-05	4	65	2	GO:1990131
GeneOntologyCellularComponent	ciliary transition fiber	FBF1 DZIP1	4.22e-04	10	65	2	GO:0097539
GeneOntologyCellularComponent	centriolar satellite	ODF2L DZIP1 PXK RAB11FIP3	6.80e-04	128	65	4	GO:0034451
Domain	EF_HAND_1	STIM1 TCHH DST RPTN ITSN1 NUCB1 ACTN1 RAB11FIP3	3.60e-07	204	62	8	PS00018
Domain	EF_HAND_2	STIM1 TCHH DST RPTN ITSN1 NUCB1 ACTN1 RAB11FIP3	9.23e-07	231	62	8	PS50222
Domain	EF_hand_dom	STIM1 TCHH DST RPTN ITSN1 NUCB1 ACTN1 RAB11FIP3	9.53e-07	232	62	8	IPR002048
Domain	EF-hand_1	TCHH DST RPTN NUCB1 ACTN1 RAB11FIP3	1.11e-05	152	62	6	PF00036
Domain	-	TCHH DST RPTN ITSN1 NUCB1 ACTN1 RAB11FIP3	2.45e-05	261	62	7	1.10.238.10
Domain	EF_Hand_1_Ca_BS	TCHH DST RPTN ITSN1 NUCB1 ACTN1	2.47e-05	175	62	6	IPR018247
Domain	EF-hand-dom_pair	TCHH DST RPTN ITSN1 NUCB1 ACTN1 RAB11FIP3	4.49e-05	287	62	7	IPR011992
Domain	Gtr1_RagA	RRAGD RRAGC	6.48e-05	4	62	2	PF04670
Domain	Gtr1_RagA	RRAGD RRAGC	6.48e-05	4	62	2	IPR006762
Domain	TTL	TTLL9 TTLL7	8.26e-04	13	62	2	PS51221
Domain	TTL/TTLL_fam	TTLL9 TTLL7	8.26e-04	13	62	2	IPR004344
Domain	TTL	TTLL9 TTLL7	8.26e-04	13	62	2	PF03133
Domain	EFh	DST ITSN1 ACTN1 RAB11FIP3	1.88e-03	158	62	4	SM00054
Domain	Ez/rad/moesin-like	EZR PTPN3	2.19e-03	21	62	2	IPR000798
Domain	Actinin_actin-bd_CS	DST ACTN1	2.62e-03	23	62	2	IPR001589
Domain	Spectrin	DST ACTN1	2.62e-03	23	62	2	PF00435
Domain	ACTININ_2	DST ACTN1	2.62e-03	23	62	2	PS00020
Domain	ACTININ_1	DST ACTN1	2.62e-03	23	62	2	PS00019
Domain	FERM_CS	EZR PTPN3	2.85e-03	24	62	2	IPR019747
Domain	FERM_C	EZR PTPN3	3.35e-03	26	62	2	PF09380
Domain	S100_CABP	TCHH RPTN	3.61e-03	27	62	2	PS00303
Domain	S_100	TCHH RPTN	3.61e-03	27	62	2	PF01023
Domain	FERM_C	EZR PTPN3	3.61e-03	27	62	2	SM01196
Domain	FERM_PH-like_C	EZR PTPN3	3.61e-03	27	62	2	IPR018980
Domain	S100_Ca-bd_sub	TCHH RPTN	3.88e-03	28	62	2	IPR013787
Domain	S100/CaBP-9k_CS	TCHH RPTN	3.88e-03	28	62	2	IPR001751
Domain	S_100	TCHH RPTN	3.88e-03	28	62	2	SM01394
Domain	Spectrin_repeat	DST ACTN1	4.16e-03	29	62	2	IPR002017
Domain	ATP_grasp_subdomain_2	TTLL9 TTLL7	4.74e-03	31	62	2	IPR013816
Domain	Spectrin/alpha-actinin	DST ACTN1	5.04e-03	32	62	2	IPR018159
Domain	SPEC	DST ACTN1	5.04e-03	32	62	2	SM00150
Domain	FERM_N	EZR PTPN3	5.36e-03	33	62	2	PF09379
Domain	FERM_N	EZR PTPN3	5.36e-03	33	62	2	IPR018979
Domain	Kinase-like_dom	DST RPS6KA5 NTRK1 PRKG1 PXK MAP3K4	9.04e-03	542	62	6	IPR011009
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	EZR ODF2L CFAP91 DST WIZ CEP85L ITSN1 NUCB1 TRIOBP ACTN1 DZIP1 JAKMIP3 PRDM4	8.92e-07	1285	67	13	35914814
Pubmed	The cytoskeletal proteins alpha-actinin, Ezrin, and talin are De-expressed in endometriosis and endometrioid carcinoma compared with normal uterine epithelium.	EZR ACTN1	3.66e-06	2	67	2	17525629
Pubmed	A human MAP kinase interactome.	PTPN3 DST HDAC4 RPS6KA5 ITSN1 NAV1 ACTN1 MAP3K4	4.35e-06	486	67	8	20936779
Pubmed	A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits.	FCHSD2 ITSN1	1.10e-05	3	67	2	29887380
Pubmed	Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes.	HDAC4 PHF21A	1.10e-05	3	67	2	35982159
Pubmed	The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.	RRAGD RRAGC	1.10e-05	3	67	2	24095279
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	RNF2 WIZ EP400 INTS13 PHF21A KNL1	1.33e-05	268	67	6	33640491
Pubmed	A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway.	STIM1 HDAC4	2.19e-05	4	67	2	29227474
Pubmed	Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes.	EZR ACTN1	2.19e-05	4	67	2	8713105
Pubmed	The DNA sequence and analysis of human chromosome 6.	ADGB EZR GABRR1 DST RRAGD UPF2 WDR46 RAB44	2.58e-05	622	67	8	14574404
Pubmed	cGMP-mediated signaling via cGKIalpha is required for the guidance and connectivity of sensory axons.	NTRK1 PRKG1	3.64e-05	5	67	2	12417579
Pubmed	PNUTS forms a trimeric protein complex with GABA(C) receptors and protein phosphatase 1.	PPP1R3A GABRR1	3.64e-05	5	67	2	18325784
Pubmed	Molecular basis for RASSF10/NPM/RNF2 feedback cascade-mediated regulation of gastric cancer cell proliferation.	RNF2 RASSF10	3.64e-05	5	67	2	34224728
Pubmed	SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling.	RRAGD RRAGC	3.64e-05	5	67	2	22575674
Pubmed	A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome.	RRAGD RRAGC	3.64e-05	5	67	2	32612235
Pubmed	A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D.	RRAGD RRAGC	5.46e-05	6	67	2	14660641
Pubmed	An EB1-binding motif acts as a microtubule tip localization signal.	STIM1 DST	5.46e-05	6	67	2	19632184
Pubmed	Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B.	RRAGD RRAGC	5.46e-05	6	67	2	11073942
Pubmed	Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2.	RRAGD RRAGC	5.46e-05	6	67	2	24529380
Pubmed	Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases.	RRAGD RRAGC	5.46e-05	6	67	2	24081491
Pubmed	The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.	RRAGD RRAGC	5.46e-05	6	67	2	18497260
Pubmed	Myogenin and class II HDACs control neurogenic muscle atrophy by inducing E3 ubiquitin ligases.	DST HDAC4	5.46e-05	6	67	2	20887891
Pubmed	Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain.	ACTN1 DZIP1 PXK	5.94e-05	39	67	3	22802532
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	STIM1 PTPN3 DST RNF2 RPS6KA5 PRKG1 MAP3K4 KNL1 CEP55	6.07e-05	910	67	9	36736316
Pubmed	SOCS2 Binds to and Regulates EphA2 through Multiple Mechanisms.	EZR DST NUCB1 KNL1	6.23e-05	110	67	4	28883622
Pubmed	Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.	FCHSD2 DST CEP85L ITSN1	6.45e-05	111	67	4	22558309
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	ODF2L HDAC4 CEP85L INTS13 ITSN1 NUCB1 WDR46 ACTN1 PRDM4	6.88e-05	925	67	9	28986522
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DST EP400 FBF1 TRIOBP CACNA1G DZIP1 PHF21A	7.16e-05	529	67	7	14621295
Pubmed	Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis.	RNF2 EP400 MXD1	7.43e-05	42	67	3	29028833
Pubmed	Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.	RRAGD RRAGC	7.63e-05	7	67	2	25259925
Pubmed	RNA Binding Protein Ptbp2 Is Essential for Male Germ Cell Development.	ACTN1 DZIP1	7.63e-05	7	67	2	26391954
Pubmed	The Absence of Sensory Axon Bifurcation Affects Nociception and Termination Fields of Afferents in the Spinal Cord.	NTRK1 PRKG1	1.02e-04	8	67	2	29472841
Pubmed	Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli.	EZR ACTN1	1.02e-04	8	67	2	10793131
Pubmed	Amino acid-dependent NPRL2 interaction with Raptor determines mTOR Complex 1 activation.	RRAGD RRAGC	1.02e-04	8	67	2	26582740
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	ITSN1 FBF1 NUCB1 TRIOBP ACTN1 PSPC1 CCDC136	1.02e-04	560	67	7	21653829
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	DST HDAC4 EP400 NAV1	1.19e-04	130	67	4	12421765
Pubmed	iASPP-PP1 complex is required for cytokinetic abscission by controlling CEP55 dephosphorylation.	PPP1R3A CEP55	1.30e-04	9	67	2	29743530
Pubmed	Identification of novel genetic loci for bone size and mechanosensitivity in an ENU mutant exhibiting decreased bone size.	GABRR1 RRAGD	1.30e-04	9	67	2	15883645
Pubmed	Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.	RRAGD RRAGC	1.30e-04	9	67	2	24337580
Pubmed	Phosphorylation of the recombinant rho1 GABA receptor.	GABRR1 PRKG1	1.30e-04	9	67	2	12175859
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	RNF2 WIZ EP400 INTS13 SF3A3 PSPC1	1.43e-04	411	67	6	35182466
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	DST WIZ GCC2 NAV1 PHF21A KNL1	1.56e-04	418	67	6	34709266
Pubmed	Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity.	NTRK1 PRKG1	1.63e-04	10	67	2	22427743
Pubmed	Esco2 is a novel corepressor that associates with various chromatin modifying enzymes.	HDAC4 PHF21A	1.63e-04	10	67	2	18501190
Pubmed	Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway.	RRAGD RRAGC	1.63e-04	10	67	2	22424946
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	ODF2L CEP85L FBF1 CEP55	1.86e-04	146	67	4	21399614
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	RNF2 WIZ EP400 INTS13	1.86e-04	146	67	4	23892456
Pubmed	Ventral migration of early-born neurons requires Dcc and is essential for the projections of primary afferents in the spinal cord.	FOXD3 NTRK1	1.99e-04	11	67	2	15788454
Pubmed	Neurogenin1 and neurogenin2 control two distinct waves of neurogenesis in developing dorsal root ganglia.	FOXD3 NTRK1	1.99e-04	11	67	2	10398684
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	RNF2 WIZ EP400 PHF21A	2.06e-04	150	67	4	28242625
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	STIM1 EZR CFAP91 RNF2 HDAC4 GCC2 SF3A3 NAV1 ACTN1 PHF21A	2.09e-04	1321	67	10	27173435
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	RNF2 WIZ EP400 PRKG1 CEP55	2.13e-04	281	67	5	24163370
Pubmed	Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.	RRAGD RRAGC	2.38e-04	12	67	2	20381137
Pubmed	SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1.	RRAGD RRAGC	2.38e-04	12	67	2	25561175
Pubmed	Phosphorylation of mouse LASP-1 on threonine 156 by cAMP- and cGMP-dependent protein kinase.	ACTN1 PRKG1	2.38e-04	12	67	2	15465019
Pubmed	PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.	RNF2 EP400 PHF21A	2.74e-04	65	67	3	22496869
Pubmed	A targeted multienzyme mechanism for selective microtubule polyglutamylation.	TTLL9 TTLL7	2.81e-04	13	67	2	17499049
Pubmed	Proteomic discovery of Max as a novel interacting partner of C/EBPalpha: a Myc/Max/Mad link.	ACTN1 MXD1	3.28e-04	14	67	2	17082780
Pubmed	Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB.	RPS6KA5 PRKG1	3.28e-04	14	67	2	9687510
Pubmed	Tubulin polyglutamylase enzymes are members of the TTL domain protein family.	TTLL9 TTLL7	3.28e-04	14	67	2	15890843
Pubmed	TBK1 Provides Context-Selective Support of the Activated AKT/mTOR Pathway in Lung Cancer.	RRAGD RRAGC	3.28e-04	14	67	2	28716898
Pubmed	Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.	RNF2 EP400 PSPC1 PHF21A	3.87e-04	177	67	4	26206133
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	DST RNF2 MAMLD1 SF3A3 ACTN1	3.98e-04	322	67	5	26514267
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	EZR DST WIZ EP400 SF3A3 PSPC1	4.34e-04	506	67	6	30890647
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	STIM1 RNF2 WIZ UPF2 WDR46 TRIOBP CEP55	4.85e-04	724	67	7	36232890
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	EZR DST WIZ HDAC4 ITSN1 NAV1 TRIOBP JAKMIP3	5.16e-04	963	67	8	28671696
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	WIZ EP400 UPF2 WDR46 PSPC1	5.17e-04	341	67	5	32971831
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	DST RNF2 WIZ EP400 INTS13 GOLIM4 TRIOBP ACTN1 PSPC1 CEP55	5.61e-04	1497	67	10	31527615
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	RNF2 WIZ EP400	5.62e-04	83	67	3	28794006
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	GCC2 DENND5A RAB11FIP3	6.45e-04	87	67	3	12465718
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	EZR PTPN3 DST UPF2 SF3A3 NAV1 ACTN1 PSPC1 CEP55	6.64e-04	1257	67	9	36526897
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	EZR RNF2 WIZ EP400 ACTN1 CEP55	6.65e-04	549	67	6	38280479
Pubmed	QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function.	DST CACNA1G	6.79e-04	20	67	2	33397958
Pubmed	Lbx1 specifies somatosensory association interneurons in the dorsal spinal cord.	FOXD3 NTRK1	7.50e-04	21	67	2	12062038
Pubmed	Large-scale concatenation cDNA sequencing.	CSRNP2 HDAC4 CEP85L LRRC8D RRAGC RAB11FIP3	7.94e-04	568	67	6	9110174
Pubmed	A "double adaptor" method for improved shotgun library construction.	CSRNP2 HDAC4 CEP85L LRRC8D RRAGC RAB11FIP3	8.38e-04	574	67	6	8619474
Pubmed	The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord.	NTRK1 PRKG1	9.01e-04	23	67	2	17954614
Pubmed	Embryonic lethality in mice lacking Trim59 due to impaired gastrulation development.	TRIOBP ACTN1	9.01e-04	23	67	2	29467473
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	RNF2 WIZ EP400 INTS13 SF3A3 ACTN1	9.08e-04	583	67	6	29844126
Pubmed	Functional proteomics mapping of a human signaling pathway.	EVC2 DST CSRNP2 ITSN1 PRDM4 KNL1	9.74e-04	591	67	6	15231748
Pubmed	Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.	TTLL9 TTLL7	1.07e-03	25	67	2	29593216
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	EZR DST WIZ EP400 UPF2 SF3A3 TRIOBP PSPC1	1.10e-03	1082	67	8	38697112
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FCHSD2 EP400 GCC2 NAV1 MAP3K4	1.14e-03	407	67	5	12693553
Pubmed	Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach.	FCHSD2 ITSN1 SF3A3	1.14e-03	106	67	3	18654987
Pubmed	Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death.	DST NTRK1	1.15e-03	26	67	2	26857994
Pubmed	Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	EP400 FBF1 CCDC136	1.18e-03	107	67	3	11347906
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	DST RNF2 EP400 WDR46 SF3A3	1.18e-03	410	67	5	26949251
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	EZR WIZ HDAC4 EP400 ACTN1 PSPC1 PHF21A KNL1	1.24e-03	1103	67	8	34189442
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DST WIZ EP400 NAV1 DENND5A ANO8 EVI5L RAB11FIP3	1.26e-03	1105	67	8	35748872
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXD3 RNF2 WIZ EP400 SF3A3 PHF21A TTLL7	1.30e-03	857	67	7	25609649
Pubmed	Interactome mapping suggests new mechanistic details underlying Alzheimer's disease.	ACTN1 EVI5L CEP55	1.31e-03	111	67	3	21163940
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	STIM1 PTPN3 DST HDAC4 CEP85L NAV1 DZIP1	1.33e-03	861	67	7	36931259
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TCHH WIZ EP400 INTS13 FBF1 PHF21A EVI5L KNL1	1.34e-03	1116	67	8	31753913
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	RNF2 TTLL9 INTS13 GCC2 FBF1 KNL1	1.44e-03	638	67	6	31182584
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	HDAC4 EP400 ITSN1 PRDM4 CEP55	1.45e-03	430	67	5	35044719
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	DST ITSN1 NAV1	1.63e-03	120	67	3	31413325
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	EZR EP400 MAMLD1 ACTN1 PHF21A	1.67e-03	444	67	5	34795231
Pubmed	c-Maf is required for the development of dorsal horn laminae III/IV neurons and mechanoreceptive DRG axon projections.	FOXD3 NTRK1	1.75e-03	32	67	2	22514301
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	STIM1 DST PHF21A	1.75e-03	123	67	3	26912792
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	EZR INTS13 SF3A3 ACTN1 PSPC1	1.79e-03	451	67	5	36168627
Interaction	NDC80 interactions	ODF2L CEP85L GCC2 NTRK1 WDR46 NAV1 PSPC1 CCDC136 KNL1 CEP55	6.71e-08	312	66	10	int:NDC80
Interaction	PCM1 interactions	ODF2L HDAC4 CEP85L GCC2 NTRK1 FBF1 NAV1 TRIOBP PHF21A CEP55	1.39e-06	434	66	10	int:PCM1
Interaction	ARHGEF15 interactions	EZR PRKG1 PSPC1 CEP55	1.99e-05	49	66	4	int:ARHGEF15
Cytoband	Ensembl 112 genes in cytogenetic band chr6q15	GABRR1 RRAGD	2.55e-03	51	67	2	chr6q15
GeneFamily	EF-hand domain containing	TCHH DST RPTN ITSN1 NUCB1 RAB11FIP3	1.07e-05	219	42	6	863
GeneFamily	EF-hand domain containing\|S100 fused type protein family	TCHH RPTN	1.10e-04	7	42	2	1350
GeneFamily	Tubulin tyrosine ligase family	TTLL9 TTLL7	4.71e-04	14	42	2	779
Coexpression	GAVIN_FOXP3_TARGETS_CLUSTER_P7	DST ACTN1 DENND5A LRRC8D MXD1	3.16e-06	91	65	5	M1736
Coexpression	GAVIN_FOXP3_TARGETS_CLUSTER_P7	DST ACTN1 DENND5A LRRC8D MXD1	3.52e-06	93	65	5	MM1218
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	FCHSD2 DST RNF2 HDAC4 UPF2 GCC2 ITSN1 MAMLD1 DENND5A PHF21A MAP3K4	7.56e-06	856	65	11	M4500
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FCHSD2 CEP85L MAMLD1 PRKG1 OVCH1	5.80e-06	170	67	5	876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FCHSD2 CEP85L MAMLD1 PRKG1 OVCH1	5.80e-06	170	67	5	1f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCell	facs-Skin-Telogen-3m-Epithelial\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STIM1 EZR DST CYP4B1 GOLIM4	1.10e-05	194	67	5	4d7fc4d0a55abb3b645116d13a983bbedc55f70c
ToppCell	facs-Skin-Telogen-3m\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STIM1 EZR DST CYP4B1 GOLIM4	1.10e-05	194	67	5	ba10fc5929649bb994c3f1d2ce6ca3167fa9b11b
ToppCell	facs-Skin-Telogen\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STIM1 EZR DST CYP4B1 GOLIM4	1.10e-05	194	67	5	bafecab8d48fc94ffd93f0d054b5f32c04b6b3f6
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST CYP4B1 GOLIM4 ACTN1 TTLL7	1.16e-05	196	67	5	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DST ITSN1 ACTN1 PRKG1 DZIP1	1.27e-05	200	67	5	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	LPS-IL1RA-Myeloid-Monocytes,_Macrophages-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1G JAKMIP3 OVCH1 MXD1	5.75e-05	139	67	4	505bf5a483fc2ba69377db9850c3b26ab2f416d1
ToppCell	MS-CD8-exh_CD4\|MS / Condition, Cell_class and T cell subcluster	PTPN3 EVC2 WIZ TTLL9	6.25e-05	142	67	4	7591491520a883bb09fa2b8d0a20ae2abd2b8703
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-valve_cells\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R3A FOXD3 CFAP91 PRKG1	8.34e-05	153	67	4	1440f2716fea74e2c3eb2924eba3d63ebd08c997
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NTRK1 GOLIM4 ACTN1 MXD1	9.22e-05	157	67	4	0673c7161c25feceee8f1e5fd237171576c42c6b
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NTRK1 GOLIM4 ACTN1 MXD1	9.22e-05	157	67	4	d307d0b48af35e0e1af41ecd3ebf91be8fd29dc0
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN3 KNL1 CEP55 RAB11FIP3	9.45e-05	158	67	4	ee8ce3cd202807df692b28bb1a81827d49d73862
ToppCell	10x5'-bone_marrow-Mast\|bone_marrow / Manually curated celltypes from each tissue	NTRK1 JAKMIP3 RAB44 TTLL7	9.68e-05	159	67	4	c3d3570e83c5d25cc92fa3a7a8f0dc2f89a72913
ToppCell	10x5'-bone_marrow-Mast-Mast_cells\|bone_marrow / Manually curated celltypes from each tissue	NTRK1 JAKMIP3 RAB44 TTLL7	1.02e-04	161	67	4	15ba7e69699558353cfeecdcf1dbc2e147379ed6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FCHSD2 MAMLD1 PRKG1 OVCH1	1.09e-04	164	67	4	b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	MAMLD1 PRKG1 CCDC136 TTLL7	1.12e-04	165	67	4	3d2acdae0dd2b79a15f74158e8e566ce22b4218e
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Myeloid-neutrophil\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASSF10 ACTN1 RAB44 MXD1	1.12e-04	165	67	4	4fe7c3c9370a556cf4e308a2e723b4b907a6cc25
ToppCell	5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD31 RPS6KA5 NTRK1 RAB44	1.17e-04	167	67	4	0aa1973141a2437df24c9857cd50ff3dfc7673c0
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GOLIM4 ACTN1 RAB44 MXD1	1.20e-04	168	67	4	c0ff30e2c47005514131a0866cf10a1c228128fc
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCHH CSRNP2 KNL1 CEP55	1.31e-04	172	67	4	29c8510f26527d487d0fc3543102d067cdb281a6
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	FCHSD2 DST HDAC4 UPF2	1.46e-04	177	67	4	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ODF2L CYP4B1 NAV1 TTLL7	1.53e-04	179	67	4	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD31 RPS6KA5 NTRK1 RAB44	1.53e-04	179	67	4	40441de2d679733ecbf2145fabc3ed65a53310eb
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGB NAV1 PRKG1 CCDC136	1.56e-04	180	67	4	9db9899ca42455310e9b63df523fe6c4780abfb7
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADGB ODF2L CFAP91 TTLL7	1.56e-04	180	67	4	92fb01b91261b3103454924cde56add337b41844
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2\|TCGA-Skin / Sample_Type by Project: Shred V9	RRAGD RPS6KA5 ACTN1 RRAGC	1.59e-04	181	67	4	9d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NTRK1 RAB44 CCDC136 TTLL7	1.70e-04	184	67	4	ce31684772e47a294155f368e50b49753f7c8e87
ToppCell	tumor_Lung-Epithelial_cells-tS3\|Epithelial_cells / Location, Cell class and cell subclass	ADGB CFAP91 TTLL9 TTLL7	1.81e-04	187	67	4	3cea677279e71fdb9879530dea10a5e6393beacd
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	DST ACTN1 PRKG1 TTLL7	1.81e-04	187	67	4	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FCHSD2 DST GOLIM4 NAV1	1.84e-04	188	67	4	9fc3819aae5a2b2534cb131d467435b5cfc420d6
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FCHSD2 DST GOLIM4 NAV1	1.84e-04	188	67	4	5e5d779ea079d3b2a1ef650b06b9f5cc1ffef5e7
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EZR PTPN3 DST DZIP1	1.88e-04	189	67	4	aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EZR PTPN3 DST DZIP1	1.88e-04	189	67	4	8977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DST ACTN1 PRKG1 TTLL7	1.92e-04	190	67	4	2e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DST ACTN1 PRKG1 TTLL7	1.92e-04	190	67	4	0028f886c789ba238c031eae5d96acaed4af8c25
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EZR FCHSD2 UPF2 PRDM4	1.92e-04	190	67	4	0db545a4cba7534bad2693e0d565cde7dbc7a586
ToppCell	COPD-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	EZR FCHSD2 UPF2 PRDM4	1.92e-04	190	67	4	1e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EPSTI1 MAMLD1 ACTN1 PRKG1	1.96e-04	191	67	4	08720998aa55131d7377c4c67c4c935865bd7d79
ToppCell	10x5'-bone_marrow-Lymphocytic_B-Memory_B_cells\|bone_marrow / Manually curated celltypes from each tissue	EZR FCHSD2 UPF2 PRDM4	1.96e-04	191	67	4	67479df0ca4c5a792fd604aded3f75609fec0888
ToppCell	ASK452-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	ADGB ODF2L CFAP91 CYP4B1	2.04e-04	193	67	4	c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	EZR FCHSD2 PRDM4 PXK	2.04e-04	193	67	4	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R3A CYP4B1 NAV1 TTLL7	2.04e-04	193	67	4	826b8dd801298b3e0cd76232feae5a14026b8806
ToppCell	Severe_COVID-19-Myeloid-proliferating_Myeloid_cells\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	DST OVCH1 KNL1 CEP55	2.04e-04	193	67	4	0d85025690c9cd545cba30abc38acbdd6a39b153
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R3A CYP4B1 NAV1 TTLL7	2.04e-04	193	67	4	87d3a577d37fb0cb4b6313c596310de452bc3872
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RRAGD ACTN1 RAB44 KNL1	2.04e-04	193	67	4	ccab6a0c76f574ef7e1d6d5f1e620376daf21bbf
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DST OVCH1 KNL1 CEP55	2.08e-04	194	67	4	cb39850e9577015b6b9834e98c36b412bae7d462
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DST OVCH1 KNL1 CEP55	2.08e-04	194	67	4	408597c9aa302a44b112c1d612c21fbb0227a82a
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DST OVCH1 KNL1 CEP55	2.08e-04	194	67	4	193cc20fefbd795a4ad59e401a95af47d30603e7
ToppCell	BAL-Severe-Myeloid-Myeloid\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DST OVCH1 KNL1 CEP55	2.08e-04	194	67	4	2360b5f995b360419de41612368cab9fb61781a1
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	DST OVCH1 KNL1 CEP55	2.08e-04	194	67	4	903ae11708b0cb24538c6982abd57fe6fa95b8d3
ToppCell	BAL-Severe-Myeloid-Myeloid\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	DST OVCH1 KNL1 CEP55	2.08e-04	194	67	4	58406502a8cbcc3037f79a1b6a683df408297ae5
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	DST CYP4B1 EVI5L RAB11FIP3	2.08e-04	194	67	4	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RRAGD ACTN1 RAB44 KNL1	2.08e-04	194	67	4	23318a1b55895b5166c6151f488a94a09b4627ff
ToppCell	BLOOD--(1)_T_cell-(1)_Activated_T_cells\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	EZR EPSTI1 KNL1 CEP55	2.08e-04	194	67	4	6a0cbb9d5c5c4effb02dff654c6c3b184026875c
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	DST CYP4B1 EVI5L RAB11FIP3	2.08e-04	194	67	4	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD31 RPS6KA5 NTRK1 TTLL7	2.08e-04	194	67	4	9d7f232ef5f27c28f325edfa6614f479013acbba
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DST MAMLD1 ACTN1 PRKG1	2.12e-04	195	67	4	d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST CYP4B1 GOLIM4 ACTN1	2.16e-04	196	67	4	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITSN1 MAMLD1 ACTN1 PRKG1	2.16e-04	196	67	4	3a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITSN1 MAMLD1 ACTN1 PRKG1	2.16e-04	196	67	4	bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADGB ODF2L CFAP91 TTLL9	2.20e-04	197	67	4	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	distal-1-Hematologic-Basophil/Mast_1\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANKRD31 RPS6KA5 NTRK1 RAB44	2.20e-04	197	67	4	e33752427eefeacbbc538e1b35f37194bdabfc40
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	RPS6KA5 NTRK1 RAB44 TTLL7	2.25e-04	198	67	4	2e6630eab77b12a6059682ab5ba465f38e469102
ToppCell	10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	RPS6KA5 NTRK1 RAB44 TTLL7	2.25e-04	198	67	4	a1247a5efd92f95c6227c0e71dc8a0427eb54b7f
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DST ITSN1 PRKG1 DZIP1	2.29e-04	199	67	4	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ODF2L EP400 UPF2 TTLL7	2.29e-04	199	67	4	174f6013af6eafa577f84205a62927f2b367fda3
ToppCell	human_hepatoblastoma-Tumor_cells-T9\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	EZR NUCB1 DENND5A MXD1	2.29e-04	199	67	4	e9c83555d2197b740797a9f33b64f8f7a7ba1ee2
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	WIZ RRAGD NAV1 DENND5A	2.29e-04	199	67	4	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	COVID-19-kidney-Fibroblast-1\|kidney / Disease (COVID-19 only), tissue and cell type	DST MAMLD1 ACTN1 PRKG1	2.29e-04	199	67	4	9503646ff1ad248181146ce767e9d12e882ec3bd
ToppCell	mild-cDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DST EPSTI1 GOLIM4 NAV1	2.33e-04	200	67	4	86f585bf9066b179bbcbc703bf43f15da4a07284
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-Mesoderm\|10w / Sample Type, Dataset, Time_group, and Cell type.	PTPN3 FBF1 GOLIM4 MAP3K4	2.33e-04	200	67	4	9ef226ebb0a7cdb9431e2fa65faa2a7d67da590d
ToppCell	NS-moderate-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EZR PTPN3 ODF2L CYP4B1	2.33e-04	200	67	4	64462a18afca3c1a8548a857924b8166058bf958
ToppCell	10x5'v1-week_12-13-Myeloid_neutrophil-granulo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	RPS6KA5 NTRK1 RAB44 MXD1	2.33e-04	200	67	4	cad2d972aa6ea0cc9ebe5ec60fda6e306e9ee2b2
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DST ITSN1 PRKG1 DZIP1	2.33e-04	200	67	4	c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCell	Control_saline-Endothelial-Endothelial-Artery\|Control_saline / Treatment groups by lineage, cell group, cell type	DST RPS6KA5 MAMLD1 GOLIM4	2.33e-04	200	67	4	65b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DST ACTN1 PRKG1 DZIP1	2.33e-04	200	67	4	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	DST ITSN1 PRKG1 PHF21A	2.33e-04	200	67	4	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
Disease	hereditary sensory neuropathy (implicated_via_orthology)	DST NTRK1	4.91e-05	5	66	2	DOID:0050548 (implicated_via_orthology)
Disease	follicular lymphoma (implicated_via_orthology)	RRAGD RRAGC	4.91e-05	5	66	2	DOID:0050873 (implicated_via_orthology)
Disease	Neuralgia, Supraorbital	NTRK1 PRKG1	5.79e-04	16	66	2	C0038870
Disease	Neuralgia, Iliohypogastric Nerve	NTRK1 PRKG1	5.79e-04	16	66	2	C0423712
Disease	Neuralgia, Perineal	NTRK1 PRKG1	5.79e-04	16	66	2	C0423711
Disease	Neuralgia	NTRK1 PRKG1	5.79e-04	16	66	2	C0027796
Disease	Neuralgia, Atypical	NTRK1 PRKG1	5.79e-04	16	66	2	C0234247
Disease	Neuralgia, Stump	NTRK1 PRKG1	5.79e-04	16	66	2	C0234249
Disease	Paroxysmal Nerve Pain	NTRK1 PRKG1	5.79e-04	16	66	2	C0751373
Disease	Nerve Pain	NTRK1 PRKG1	5.79e-04	16	66	2	C0751372
Disease	Neuralgia, Ilioinguinal	NTRK1 PRKG1	5.79e-04	16	66	2	C0751371
Disease	Neuralgia, Vidian	NTRK1 PRKG1	5.79e-04	16	66	2	C0042656
Disease	wellbeing measurement, alcohol consumption measurement	DST GOLIM4 RRAGC	6.19e-04	74	66	3	EFO_0007869, EFO_0007878
Disease	hypertrophic cardiomyopathy	CEP85L CCDC136 PHF21A	1.16e-03	92	66	3	EFO_0000538
Disease	Ovarian Serous Adenocarcinoma	NTRK1 MAP3K4	1.21e-03	23	66	2	C1335177

Protein segments in the cluster

Peptide	Gene	Start	Entry
QRVVELETQDHIHRN	EVI5L	581	Q96CN4
VRTVVRHHEEKQLRE	EP400	841	Q96L91
EHARQQHNERLRKQF	ACTN1	621	P12814
KAEEIHQFRQHRTRV	ADGB	1566	Q8N7X0
AQEQEVNHREILREH	CSRNP2	111	Q9H175
QRRADVQHLEDDRHK	CEP55	286	Q53EZ4
QRQRNLHEHKVSLVE	CFAP91	551	Q7Z4T9
QRREAFKRHERQAQH	ANO8	881	Q9HCE9
DHTIRQQVQRLHELD	RASSF10	236	A6NK89
QQVQRLHELDREIDH	RASSF10	241	A6NK89
HERLQIQIHKREAEN	ODF2L	186	Q9ULJ1
TLRKRDSDHHREVQQ	RAB44	211	Q7Z6P3
HERHQFQRDKEATQE	RAB11FIP3	606	O75154
HQRQKQAESREHIVA	PTPN3	271	P26045
RAHINNSEKHQRVLE	INTS13	541	Q9NVM9
EKRRQNHLESETIHN	ANKRD31	1096	Q8N7Z5
REPQQRHSIKDVHAR	NTRK1	766	P04629
RHRQEQELEKQHREQ	HDAC4	136	P56524
VHQIDQLQREQRHLK	MXD1	116	Q05195
QQEEHRQLRELIAEH	DST	5976	Q03001
HIVDTRQQEHIRSEK	PRKG1	396	Q13976
QERAKIHQTEHRRVN	EPSTI1	271	Q96J88
THDHLEEIQSKRQER	PHF21A	376	Q96BD5
ELRQVREHEQHKTAV	JAKMIP3	56	Q5VZ66
QKHREQRREQASVGE	EVC2	681	Q86UK5
EHTRERKHANDQTVI	KNL1	156	Q8NG31
EQKASHQHQEALRRE	GOLGA6L22	61	H0YM25
EHTRTERQVLEHIRQ	RPS6KA5	96	O75582
LEEQQRRHREHPKVN	NUCB1	206	Q02818
NRNVKDVNREHDEHN	PPP1R3A	301	Q16821
ENRQLRKAHQDIHTQ	GOLIM4	181	O00461
QERLRKQEQHMHQEH	FBF1	1016	Q8TES7
RPQRQRREVHEDAHK	GABRR1	41	P24046
HKCRQHQEEEEARRR	CACNA1G	1541	O43497
LEHVQQEDEHQRPRK	ITSN1	661	Q15811
QVRHLQEEHRKTVET	GCC2	1446	Q8IWJ2
QKQQITHLHERIRDN	CEP85L	381	Q5SZL2
RQKQHTEHLRLDNDQ	DENND5A	701	Q6IQ26
HQGTVKRRQEEDHFQ	MAMLD1	56	Q13495
QVAHDHTDQVIRERK	CYP4B1	251	P13584
ARDENKRTHNDIIHN	EZR	541	P15311
AREHKNIVHQQRVLN	FCHSD2	336	O94868
DDHKIETQRDIHQRA	RRAGD	186	Q9NQL2
EAHQERVLARINKHN	RNF2	121	Q99496
RFKRHQQEHLREQTA	FOXD3	236	Q9UJU5
RQHISRNAQDKQELH	LRRC8D	461	Q7L1W4
RQDLKQHVLIHTQER	PRDM4	686	Q9UKN5
HLKRDHRELQNTERQ	UPF2	366	Q9HAU5
HEHLQRQRVSFEQVK	MAP3K4	341	Q9Y6R4
QLQSQEETKERRHSH	NAV1	951	Q8NEY1
DHKIETQRDIHQRAN	RRAGC	186	Q9HB90
QNRVTDHRINKTLHD	MTRF1L	331	Q9UGC7
TEQVRRAKHIIVHED	OVCH1	641	Q7RTY7
QHRQLHQASREKIIE	WIZ	321	O95785
RRTERNHIENILKAH	SPATA31C1	571	P0DKV0
LQERLHKAQEEHRTV	STIM1	261	Q13586
RHKQEREIPNFHQIR	DZIP1	581	Q86YF9
RHHERELQRLQQEKE	TRIOBP	2131	Q9H2D6
RAQREHEAQKQHSVE	HTR3D	406	Q70Z44
ELQHHRQVSEEEQRR	CCDC136	326	Q96JN2
KQIQLRHEEEHRRRE	PSPC1	346	Q8WXF1
IEEQKQIHQHRRLTR	PXK	431	Q7Z7A4
EHRDKVRQSLQQQHH	WDR46	576	O15213
HRRQDVHLTNVAVQK	TTLL9	246	Q3SXZ7
EQRHLTHENVQRKQA	SF3A3	336	Q12874
NTGRQHRQRHEEERQ	RPTN	116	Q6XPR3
DEQNHQRRDRQTHEH	RPTN	736	Q6XPR3
EQSHQRRDRQTHEDK	RPTN	751	Q6XPR3
REEHIRRQQKEEQRH	TCHH	1881	Q07283
QVRKQISREEHENRH	TTLL7	436	Q6ZT98