Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphatase binding

INSR AMBRA1 SFI1 STAT1 SPTBN4 KIFAP3 DLG1 DLG2 DLG3

6.61e-06264999GO:0019902
GeneOntologyMolecularFunctionstructural constituent of postsynaptic density

DLG1 DLG2 DLG3

1.90e-0511993GO:0098919
GeneOntologyMolecularFunctionstructural constituent of postsynaptic specialization

DLG1 DLG2 DLG3

3.26e-0513993GO:0098879
GeneOntologyMolecularFunctionstructural molecule activity

INSR NUP98 ERVK13-1 CRELD2 SPTBN4 CRELD1 DST DLG1 MACF1 DLG2 DLG3 DMD NUP160 SEC13

1.25e-048919914GO:0005198
GeneOntologyMolecularFunctionnucleoside monophosphate kinase activity

AK6 DLG1 DLG2

1.95e-0423993GO:0050145
GeneOntologyMolecularFunctionferric-chelate reductase (NADPH) activity

STEAP3 STEAP1

2.41e-045992GO:0052851
GeneOntologyMolecularFunctionferric-chelate reductase activity

STEAP3 STEAP1

2.41e-045992GO:0000293
GeneOntologyMolecularFunctioncupric reductase (NADH) activity

STEAP3 STEAP1

2.41e-045992GO:0008823
GeneOntologyMolecularFunctionoxidoreductase activity, acting on metal ions, NAD or NADP as acceptor

STEAP3 STEAP1

5.03e-047992GO:0016723
GeneOntologyMolecularFunctionstructural constituent of postsynapse

DLG1 DLG2 DLG3

5.28e-0432993GO:0099186
GeneOntologyMolecularFunctionprotein phosphatase binding

INSR AMBRA1 STAT1 KIFAP3 DLG2 DLG3

6.26e-04210996GO:0019903
GeneOntologyMolecularFunctionhistone H3K4 monomethyltransferase activity

KMT2C KMT2D

6.68e-048992GO:0140945
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

KMT2C KMT2D

1.07e-0310992GO:0140999
GeneOntologyMolecularFunctionphosphotransferase activity, phosphate group as acceptor

AK6 DLG1 DLG2

1.10e-0341993GO:0016776
GeneOntologyMolecularFunctionstructural constituent of synapse

DLG1 DLG2 DLG3

1.18e-0342993GO:0098918
GeneOntologyMolecularFunctionguanylate kinase activity

DLG1 DLG2

1.30e-0311992GO:0004385
GeneOntologyMolecularFunctionnucleobase-containing compound kinase activity

AK6 DLG1 DLG2

1.64e-0347993GO:0019205
GeneOntologyMolecularFunctionintegrin binding

ITGA2B DST FCER2 DMD FERMT3

1.80e-03175995GO:0005178
GeneOntologyMolecularFunctionionotropic glutamate receptor binding

DLG1 DLG2 DLG3

2.19e-0352993GO:0035255
GeneOntologyCellularComponentnuclear pore outer ring

NUP98 NUP160 SEC13

1.24e-05101003GO:0031080
GeneOntologyCellularComponentaxon

SETX INSR SPG11 STAT1 CNTN6 SPTBN4 LRIG2 DST DLG1 DLG2 DLG3 DMD LGI1

3.23e-0489110013GO:0030424
GeneOntologyCellularComponentaxon initial segment

SPTBN4 DLG2 LGI1

3.55e-04291003GO:0043194
DomainMAGUK_N_PEST

DLG1 DLG2 DLG3

5.41e-074973PF10608
DomainPDZ_assoc

DLG1 DLG2 DLG3

5.41e-074973PF10600
DomainDLG1_PEST_dom

DLG1 DLG2 DLG3

5.41e-074973IPR019590
DomainPDZ_assoc

DLG1 DLG2 DLG3

5.41e-074973IPR019583
DomainMAGUK_N_PEST

DLG1 DLG2 DLG3

5.41e-074973SM01277
DomainDLG1

DLG1 DLG2 DLG3

5.41e-074973IPR016313
DomainActinin_actin-bd_CS

SPTBN4 DST MACF1 DMD

5.61e-0623974IPR001589
DomainSpectrin

SPTBN4 DST MACF1 DMD

5.61e-0623974PF00435
DomainACTININ_2

SPTBN4 DST MACF1 DMD

5.61e-0623974PS00020
DomainACTININ_1

SPTBN4 DST MACF1 DMD

5.61e-0623974PS00019
DomainSpectrin_repeat

SPTBN4 DST MACF1 DMD

1.47e-0529974IPR002017
DomainCH

SPTBN4 DST MICALL2 MACF1 DMD

2.20e-0565975SM00033
DomainSpectrin/alpha-actinin

SPTBN4 DST MACF1 DMD

2.20e-0532974IPR018159
DomainSPEC

SPTBN4 DST MACF1 DMD

2.20e-0532974SM00150
DomainFerric_reduct

NOX3 STEAP3 STEAP1

2.89e-0512973PF01794
DomainFe3_Rdtase_TM_dom

NOX3 STEAP3 STEAP1

2.89e-0512973IPR013130
DomainCH

SPTBN4 DST MICALL2 MACF1 DMD

3.16e-0570975PF00307
Domain-

SPTBN4 DST MICALL2 MACF1 DMD

3.38e-05719751.10.418.10
DomainCH

SPTBN4 DST MICALL2 MACF1 DMD

3.87e-0573975PS50021
DomainCH-domain

SPTBN4 DST MICALL2 MACF1 DMD

4.41e-0575975IPR001715
DomainGuanylate_kinase_CS

DLG1 DLG2 DLG3

7.24e-0516973IPR020590
DomainFurin_repeat

INSR CRELD2 CRELD1

1.05e-0418973IPR006212
DomainFU

INSR CRELD2 CRELD1

1.05e-0418973SM00261
DomainSH3

FNBP1 DST ITSN2 DLG1 MACF1 DLG2 DLG3

1.34e-04216977PS50002
DomainSH3_domain

FNBP1 DST ITSN2 DLG1 MACF1 DLG2 DLG3

1.50e-04220977IPR001452
DomainSH3_1

FNBP1 DST ITSN2 DLG1 DLG2 DLG3

2.14e-04164976PF00018
DomainGUANYLATE_KINASE_2

DLG1 DLG2 DLG3

2.23e-0423973PS50052
DomainGUANYLATE_KINASE_1

DLG1 DLG2 DLG3

2.23e-0423973PS00856
DomainFYrich_C

KMT2C KMT2D

2.64e-045972IPR003889
DomainFYrich_N

KMT2C KMT2D

2.64e-045972IPR003888
DomainFYRC

KMT2C KMT2D

2.64e-045972SM00542
DomainFYRN

KMT2C KMT2D

2.64e-045972SM00541
DomainTDE1/TMS

SERINC2 SERINC5

2.64e-045972IPR005016
DomainSerinc

SERINC2 SERINC5

2.64e-045972PF03348
DomainFYRN

KMT2C KMT2D

2.64e-045972PF05964
DomainFYRC

KMT2C KMT2D

2.64e-045972PF05965
DomainFYRC

KMT2C KMT2D

2.64e-045972PS51543
DomainFYRN

KMT2C KMT2D

2.64e-045972PS51542
DomainGuanylate_kin

DLG1 DLG2 DLG3

3.24e-0426973PF00625
DomainGK/Ca_channel_bsu

DLG1 DLG2 DLG3

3.24e-0426973IPR008145
DomainGuanylate_kin-like_dom

DLG1 DLG2 DLG3

3.24e-0426973IPR008144
DomainGuKc

DLG1 DLG2 DLG3

3.24e-0426973SM00072
Domain-

DST MACF1

3.95e-0469723.90.1290.10
DomainGAR

DST MACF1

3.95e-046972PS51460
Domain-

DST MACF1

3.95e-0469723.30.920.20
DomainGAS_dom

DST MACF1

3.95e-046972IPR003108
DomainGAS2

DST MACF1

3.95e-046972PF02187
DomainGAS2

DST MACF1

3.95e-046972SM00243
Domain-

TBC1D9B STAT1 STAT4 DST ITSN2 MACF1 DMD

4.23e-042619771.10.238.10
DomainSTAT_TF_prot_interaction

STAT1 STAT4

5.51e-047972IPR013799
DomainSTAT_TF_DNA-bd_sub

STAT1 STAT4

5.51e-047972IPR012345
DomainSTAT

STAT1 STAT4

5.51e-047972IPR001217
DomainPlectin_repeat

DST MACF1

5.51e-047972IPR001101
DomainSTAT_TF_coiled-coil

STAT1 STAT4

5.51e-047972IPR015988
Domain-

STAT1 STAT4

5.51e-0479722.60.40.630
DomainDUF3456

CRELD2 CRELD1

5.51e-047972PF11938
DomainSTAT_int

STAT1 STAT4

5.51e-047972SM00964
DomainSTAT_TF_DNA-bd

STAT1 STAT4

5.51e-047972IPR013801
DomainSTAT_bind

STAT1 STAT4

5.51e-047972PF02864
DomainSTAT_int

STAT1 STAT4

5.51e-047972PF02865
DomainPlectin

DST MACF1

5.51e-047972PF00681
DomainDUF3456

CRELD2 CRELD1

5.51e-047972IPR021852
Domain-

STAT1 STAT4

5.51e-0479721.10.532.10
DomainSTAT_alpha

STAT1 STAT4

5.51e-047972PF01017
Domain-

STAT1 STAT4

5.51e-0479721.20.1050.20
DomainPLEC

DST MACF1

5.51e-047972SM00250
DomainSTAT_TF_alpha

STAT1 STAT4

7.32e-048972IPR013800
DomainEF-hand-dom_pair

TBC1D9B STAT1 STAT4 DST ITSN2 MACF1 DMD

7.43e-04287977IPR011992
DomainPeptidase_M1

ERAP2 LTA4H

1.70e-0312972IPR001930
DomainPeptidase_M1

ERAP2 LTA4H

2.01e-0313972PF01433
Domain6-hairpin_glycosidase-like

SPATA20 TREH

2.01e-0313972IPR008928
DomainPeptidase_M1_N

ERAP2 LTA4H

2.01e-0313972IPR014782
DomainPost-SET_dom

KMT2C KMT2D

3.06e-0316972IPR003616
DomainPostSET

KMT2C KMT2D

3.06e-0316972SM00508
DomainPOST_SET

KMT2C KMT2D

3.06e-0316972PS50868
DomainGal_mutarotase_SF_dom

MAN2B1 LGI1

3.45e-0317972IPR011013
PathwayBIOCARTA_PDZS_PATHWAY

DLG1 DLG2 DLG3

1.07e-0418743M22001
PathwayREACTOME_RAS_ACTIVATION_UPON_CA2_INFLUX_THROUGH_NMDA_RECEPTOR

DLG1 DLG2 DLG3

1.48e-0420743M17670
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

DLG1 DLG2 DLG3

1.73e-0421743M838
PathwayREACTOME_NEGATIVE_REGULATION_OF_NMDA_RECEPTOR_MEDIATED_NEURONAL_TRANSMISSION

DLG1 DLG2 DLG3

1.73e-0421743M27944
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

DLG1 DLG2 DLG3

1.99e-0422743MM15104
PathwayREACTOME_LONG_TERM_POTENTIATION

DLG1 DLG2 DLG3

2.28e-0423743M27949
PathwayREACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION

NUP98 NUP160 SEC13

2.60e-0424743MM15658
PathwayREACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION

NUP98 NUP160 SEC13

3.71e-0427743M29807
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING

DLG1 DLG2 DLG3

4.14e-0428743M837
PathwayREACTOME_L1CAM_INTERACTIONS

ITGA2B CNTN6 SPTBN4 DLG1 DLG3

4.31e-04121745M872
PathwayREACTOME_NRCAM_INTERACTIONS

DLG1 DLG3

5.61e-047742M27378
PathwayREACTOME_ISG15_ANTIVIRAL_MECHANISM

NUP98 STAT1 NUP160 SEC13

6.10e-0474744M48006
PathwayREACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN

NUP98 NUP160 SEC13

6.17e-0432743M29579
PathwayREACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS

NUP98 NUP160 SEC13

6.77e-0433743M27016
PathwayREACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN

NUP98 NUP160 SEC13

7.39e-0434743M27041
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

NUP98 NUP160 SEC13

8.05e-0435743M27320
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

DLG1 DLG2 DLG3

8.05e-0435743MM15109
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

NUP98 NUP160 SEC13

8.75e-0436743M26974
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

NUP98 NUP160 SEC13

8.75e-0436743M27245
PathwayREACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS

NUP98 NUP160 SEC13

9.49e-0437743M1029
PathwayREACTOME_INTERACTIONS_OF_REV_WITH_HOST_CELLULAR_PROTEINS

NUP98 NUP160 SEC13

9.49e-0437743M27038
PathwayREACTOME_SERINE_BIOSYNTHESIS

SERINC2 SERINC5

9.56e-049742M27959
PathwayREACTOME_SERINE_BIOSYNTHESIS

SERINC2 SERINC5

9.56e-049742MM15707
PathwayREACTOME_SARS_COV_2_INFECTION

MGAT4A NUP98 ST3GAL3 STAT1 PARP16 NUP160 SEC13

9.61e-04299747M41727
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

NUP98 NUP160 SEC13

1.11e-0339743M27238
PathwayREACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES

NUP98 STAT1 FANCA NUP160 SEC13

1.17e-03151745M550
PathwayREACTOME_INTERLEUKIN_21_SIGNALING

STAT1 STAT4

1.19e-0310742M27898
PathwayREACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS

DLG1 DLG3

1.19e-0310742M10272
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

NUP98 NUP160 SEC13

1.19e-0340743MM14945
PathwayREACTOME_NS1_MEDIATED_EFFECTS_ON_HOST_PATHWAYS

NUP98 NUP160 SEC13

1.28e-0341743M29574
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

NUP98 NUP160 SEC13

1.28e-0341743MM15200
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

NUP98 NUP160 SEC13

1.38e-0342743MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

NUP98 NUP160 SEC13

1.47e-0343743MM14609
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

NUP98 NUP160 SEC13

1.47e-0343743M26975
PathwayREACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS

NUP98 NUP160 SEC13

1.58e-0344743M109
PathwayREACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS

DLG1 DLG2 DLG3

1.58e-0344743M27934
PathwayREACTOME_INTERLEUKIN_35_SIGNALLING

STAT1 STAT4

1.73e-0312742M27860
PathwayREACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS

DLG1 DLG3

1.73e-0312742MM15142
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

NUP98 NUP160 SEC13

1.79e-0346743M27397
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

NUP98 NUP160 SEC13

1.91e-0347743M27395
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

NUP98 NUP160 SEC13

1.91e-0347743MM14939
PathwayREACTOME_GENE_SILENCING_BY_RNA

NUP98 NUP160 SEC13

2.15e-0349743MM14837
Pubmed

Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.

DST MACF1 DMD

9.78e-08410238954775
Pubmed

Expression pattern of membrane-associated guanylate kinases in interneurons of the visual cortex.

DLG1 DLG2 DLG3

9.78e-084102321031555
Pubmed

Synaptic scaffold evolution generated components of vertebrate cognitive complexity.

DLG1 DLG2 DLG3

9.78e-084102323201973
Pubmed

Sema4c, a transmembrane semaphorin, interacts with a post-synaptic density protein, PSD-95.

DLG1 DLG2 DLG3

2.44e-075102311134026
Pubmed

Selective interaction of megalin with postsynaptic density-95 (PSD-95)-like membrane-associated guanylate kinase (MAGUK) proteins.

DLG1 DLG2 DLG3

2.44e-075102312713445
Pubmed

Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.

DLG1 DLG2 DLG3 DMD

2.61e-0719102415024025
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

RABGAP1 KIFAP3 DST HOOK1 MACF1 DMD NUP160

3.31e-07151102717043677
Pubmed

Guanylyl cyclase/PSD-95 interaction: targeting of the nitric oxide-sensitive alpha2beta1 guanylyl cyclase to synaptic membranes.

DLG1 DLG2 DLG3

4.87e-076102311572861
Pubmed

Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis.

DLG1 DLG2 DLG3

4.87e-076102319118189
Pubmed

Selective binding of synapse-associated protein 97 to GluR-A alpha-amino-5-hydroxy-3-methyl-4-isoxazole propionate receptor subunit is determined by a novel sequence motif.

DLG1 DLG2 DLG3

4.87e-076102312070168
Pubmed

Plasma membrane Ca2+-atpase isoforms 2b and 4b interact promiscuously and selectively with members of the membrane-associated guanylate kinase family of PDZ (PSD95/Dlg/ZO-1) domain-containing proteins.

DLG1 DLG2 DLG3

4.87e-076102311274188
Pubmed

Inward rectifier K+ channel Kir2.3 is localized at the postsynaptic membrane of excitatory synapses.

DLG1 DLG2 DLG3

8.50e-077102311997254
Pubmed

Polarity protein complex Scribble/Lgl/Dlg and epithelial cell barriers.

DLG1 DLG2 DLG3

1.36e-068102323397623
Pubmed

Identification of multiple binding partners for the amino-terminal domain of synapse-associated protein 97.

DLG1 DLG2 DLG3

1.36e-068102312351654
Pubmed

Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex.

NUP98 NUP160 SEC13

2.03e-069102317360435
Pubmed

The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis.

NUP98 NUP160 SEC13

2.90e-0610102315146057
Pubmed

The discovery of a Werner Helicase Interacting Protein (WHIP) association with the nuclear pore complex.

NUP98 NUP160 SEC13

2.90e-0610102320676042
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

SETX INSR NUP98 KIF20A CEP350 LRIG2 DST STEAP3 DLG1 DLG3 NUP160 SEC13

3.06e-067771021235844135
Pubmed

DGKι regulates presynaptic release during mGluR-dependent LTD.

DLG1 DLG2 DLG3

3.97e-0611102321119615
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

DYNC2H1 PKD1L2 CRELD1 KMT2C DST DISP3 MACF1 DMD

5.10e-06322102826514267
Pubmed

NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation.

DLG1 DLG2 DLG3

5.29e-0612102316980967
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SETX ECT2L ICE1 TRRAP STAT1 TEFM KMT2C ZNF24 DST MICALL2 ITSN2 DLG1 MACF1 DLG3 SEC13 CKMT1A

7.37e-0614971021631527615
Pubmed

Fanconi anemia core complex gene promoters harbor conserved transcription regulatory elements.

STAT1 STAT4

8.52e-062102221826217
Pubmed

High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups.

STAT1 STAT4

8.52e-062102219333953
Pubmed

Identification, genomic organization and mRNA expression of CRELD1, the founding member of a unique family of matricellular proteins.

CRELD2 CRELD1

8.52e-062102212137942
Pubmed

Polymorphisms of signal transducers and activators of transcription 1 and 4 (STAT1 and STAT4) contribute to progression of childhood IgA nephropathy.

STAT1 STAT4

8.52e-062102220045654
Pubmed

STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge.

STAT1 STAT4

8.52e-062102224920804
Pubmed

Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.

DST MACF1

8.52e-062102211002341
Pubmed

Characterization of a single b-type heme, FAD, and metal binding sites in the transmembrane domain of six-transmembrane epithelial antigen of the prostate (STEAP) family proteins.

STEAP3 STEAP1

8.52e-062102226205815
Pubmed

cDNA cloning, expression and chromosome mapping of the human STAT4 gene: both STAT4 and STAT1 genes are mapped to 2q32.2-->q32.3.

STAT1 STAT4

8.52e-06210229284918
Pubmed

KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies.

KMT2C KMT2D

8.52e-062102231924266
Pubmed

Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region.

STAT1 STAT4

8.52e-062102218803832
Pubmed

Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.

KMT2C KMT2D

8.52e-062102228967912
Pubmed

Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA.

STAT1 STAT4

8.52e-06210229630226
Pubmed

Localization to detergent-resistant membranes and HIV-1 core entry inhibition correlate with HIV-1 restriction by SERINC5.

SERINC2 SERINC5

8.52e-062102229268082
Pubmed

Epigenetic control of innate and adaptive immune memory.

STAT1 STAT4

8.52e-062102230082830
Pubmed

Association of KMT2C/D loss-of-function variants with response to immune checkpoint blockades in colorectal cancer.

KMT2C KMT2D

8.52e-062102236601880
Pubmed

Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.

KMT2C KMT2D

8.52e-062102228483418
Pubmed

Tyrosine phosphorylation regulates the partitioning of STAT1 between different dimer conformations.

STAT1 STAT4

8.52e-062102218591661
Pubmed

The Ets transcription factor ERM is Th1-specific and induced by IL-12 through a Stat4-dependent pathway.

STAT1 STAT4

8.52e-062102210097133
Pubmed

The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.

KMT2C KMT2D

8.52e-062102234156443
Pubmed

Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma.

KMT2C KMT2D

8.52e-062102227280393
Pubmed

Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.

KMT2C KMT2D

8.52e-062102236869380
Pubmed

Disease Risk-Associated Genetic Variants in STAT1 and STAT4 Function in a Complementary Manner to Increase Pattern-Recognition Receptor-Induced Outcomes in Human Macrophages.

STAT1 STAT4

8.52e-062102232661180
Pubmed

Regulating type 1 IFN effects in CD8 T cells during viral infections: changing STAT4 and STAT1 expression for function.

STAT1 STAT4

8.52e-062102222968462
Pubmed

Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.

KMT2C KMT2D

8.52e-062102225346535
Pubmed

Cloning and characterization of E-dlg, a novel splice variant of mouse homologue of the Drosophila discs large tumor suppressor binds preferentially to SAP102.

DLG1 DLG3

8.52e-062102218618587
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

SELENBP1 DYNC2H1 NOX3 SERINC2 ARHGDIB PRCP TREH SUSD2 ATP6V0A4 ITSN2 LTA4H SERINC5 SEC13

8.86e-0610161021319056867
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SERINC2 LRIG2 DST SEL1L3 MACF1

1.25e-0510110259872452
Pubmed

Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases.

DLG1 DLG2 DLG3

1.33e-0516102321920314
Pubmed

A human MAP kinase interactome.

SETX NUP98 STAT1 CEP350 KMT2C DST ITSN2 MACF1 DMD

1.37e-05486102920936779
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

STK36 NWD2 ITSN2 MACF1 DLG3

1.37e-05103102510574462
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

STK36 TBC1D9B DYNC2H1 CEP350 LRIG2 DISP3 MACF1 KAZN NUP160

1.53e-05493102915368895
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SELENBP1 ELP1 SPTBN4 NWD2 DST ITSN2 TRAPPC10 DLG1 MACF1 DLG2 DLG3 DMD LGI1 SEC13 CKMT1A

1.84e-0514311021537142655
Pubmed

Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins.

DLG1 DLG2 DLG3

1.94e-0518102319455133
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

STK36 TBC1D9B MAN2B1 AMBRA1 SPATA20 ICE1 SFI1 TRRAP FANCA KMT2C KMT2D DST STEAP3

2.14e-0511051021335748872
Pubmed

Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome.

ITSN2 DLG1 DLG2 DLG3

2.28e-0556102422745667
Pubmed

A brain atlas of synapse protein lifetime across the mouse lifespan.

DLG2 DLG3

2.55e-053102236202095
Pubmed

IL-21 promotes differentiation of naive CD8 T cells to a unique effector phenotype.

STAT1 STAT4

2.55e-053102217548600
Pubmed

Expression of the mouse Macf2 gene during inner ear development.

DST MACF1

2.55e-053102212399109
Pubmed

The role of Tyk2, Stat1 and Stat4 in LPS-induced endotoxin signals.

STAT1 STAT4

2.55e-053102215226272
Pubmed

Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.

KMT2C KMT2D

2.55e-053102223932714
Pubmed

MAGUKs are essential, but redundant, in long-term potentiation.

DLG2 DLG3

2.55e-053102234244435
Pubmed

Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway.

DLG2 DLG3

2.55e-053102223486974
Pubmed

The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed and localised to the Golgi apparatus.

RABGAP1 KIF20A

2.55e-053102210893188
Pubmed

Architecture of the Mouse Brain Synaptome.

DLG2 DLG3

2.55e-053102230078578
Pubmed

Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.

KMT2C KMT2D

2.55e-053102222183980
Pubmed

Synapse-specific and developmentally regulated targeting of AMPA receptors by a family of MAGUK scaffolding proteins.

DLG2 DLG3

2.55e-053102217046693
Pubmed

Calcium-permeable AMPA receptors and silent synapses in cocaine-conditioned place preference.

DLG2 DLG3

2.55e-053102228077487
Pubmed

Determination of the consensus DNA-binding sequence and a transcriptional activation domain for ESE-2.

ITSN2 EHF

2.55e-053102216704374
Pubmed

HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.

KMT2C KMT2D

2.55e-053102221683083
Pubmed

SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit.

DLG1 DLG2

2.55e-05310229677374
Pubmed

Compartmentalized NRG signaling and PDZ domain-containing proteins in synapse structure and function.

DLG1 DLG3

2.55e-053102212175853
Pubmed

Trans-homophilic interaction of CADM1 activates PI3K by forming a complex with MAGuK-family proteins MPP3 and Dlg.

DLG1 DLG3

2.55e-053102225268382
Pubmed

LGI1-ADAM22-MAGUK configures transsynaptic nanoalignment for synaptic transmission and epilepsy prevention.

DLG1 LGI1

2.55e-053102233397806
Pubmed

Alternative splicing of the human Rab6A gene generates two close but functionally different isoforms.

RABGAP1 KIF20A

2.55e-053102211071909
Pubmed

Lysine methyltransferase 2D regulates muscle fiber size and muscle cell differentiation.

KMT2D DMD

2.55e-053102234613626
Pubmed

Molecular cloning and characterization of STAMP1, a highly prostate-specific six transmembrane protein that is overexpressed in prostate cancer.

STEAP3 STEAP1

2.55e-053102212095985
Pubmed

Sustained Post-Developmental T-Bet Expression Is Critical for the Maintenance of Type One Innate Lymphoid Cells In Vivo.

STAT1 STAT4

2.55e-053102234795671
Pubmed

Stat3 and Stat4: members of the family of signal transducers and activators of transcription.

STAT1 STAT4

2.55e-05310227545930
Pubmed

Distinct characteristics of murine STAT4 activation in response to IL-12 and IFN-alpha.

STAT1 STAT4

2.55e-053102217015705
Pubmed

Sec13 shuttles between the nucleus and the cytoplasm and stably interacts with Nup96 at the nuclear pore complex.

NUP98 SEC13

2.55e-053102214517296
Pubmed

Direct interaction of kindlin-3 with integrin αIIbβ3 in platelets is required for supporting arterial thrombosis in mice.

ITGA2B FERMT3

2.55e-053102224969775
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SPATA20 SPTBN4 LRIG2 DST HOOK1 DLG1 MACF1 DLG2 DLG3 EML1 FERMT3 LGI1

2.61e-059631021228671696
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

DST HOOK1 MACF1 DMD NUP160

2.87e-05120102531413325
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

FNBP1 TRPM2 INSR RABGAP1 ST3GAL3 TRRAP SPTBN4 KMT2C EHF SEL1L3 DLG1 MACF1 SLC35F2 SERINC5 STEAP1

2.92e-0514891021528611215
Pubmed

Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes.

DLG1 LGI1 CKMT1A

3.13e-0521102325707359
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

INSR DST ITSN2 STEAP3 DLG1 MACF1 DLG3 DMD

3.51e-05421102836976175
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

FNBP1 NELFA CRELD2 CBFA2T3 TMEM80 CFAP298 CRELD1 DST SERINC5 SEC13

3.98e-056971021028298427
Pubmed

Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays.

DLG1 DLG2 DLG3

4.16e-0523102316637659
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

STK36 SPTBN4 DST ITSN2 MACF1

4.21e-05130102512421765
Pubmed

GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

CNTN6 STAT4 EHF

4.74e-0524102324871463
Pubmed

Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.

KMT2C KMT2D

5.09e-054102219221051
Pubmed

Cancer gene mutation frequencies for the U.S. population.

KMT2C KMT2D

5.09e-054102234645806
Pubmed

Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-alpha/beta on antigen cross-presentation.

STAT1 STAT4

5.09e-054102217018853
Pubmed

STATs as activators of apoptosis.

STAT1 STAT4

5.09e-05410229695817
Pubmed

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6.

STAT1 STAT4

5.09e-05410228140422
Pubmed

SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes.

DLG1 DMD

5.09e-054102221164104
Pubmed

IL-23 drives pathogenic IL-17-producing CD8+ T cells.

STAT1 STAT4

5.09e-054102219380776
Pubmed

Cypin: a cytosolic regulator of PSD-95 postsynaptic targeting.

DLG1 DLG3

5.09e-054102210595517
GeneFamilyCalcium voltage-gated channel subunits|Membrane associated guanylate kinases

DLG1 DLG2 DLG3

1.04e-0426643904
GeneFamilyProteases, serine|STEAP family

STEAP3 STEAP1

1.23e-0456421324
GeneFamilyNucleoporins

NUP98 NUP160 SEC13

1.95e-04326431051
GeneFamilyEF-hand domain containing|Plakins

DST MACF1

3.41e-048642939
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

MR1 ARHGDIB PRCP

7.80e-0451643870
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

SFI1 ITGA2B DLG2 DLG3

3.87e-03181644694
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

FNBP1 SETX MGAT4A NUP98 MR1 ELP1 SPG11 ICE1 STAT1 STAT4 EPG5 CEP350 KMT2C ARHGDIB KMT2D ERAP2 ITSN2 SEL1L3 TRAPPC10 MACF1 BIN2 FERMT3

5.24e-08149210222M40023
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SETX NUP98 SPG11 RABGAP1 TRRAP CEP350 KIFAP3 DST ITSN2 DLG1 MACF1 KAZN DMD NUP160

5.85e-0685610214M4500
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MGAT4A GCNT4 STAT4 ARHGDIB BIN2 SERINC5 DTHD1

2.36e-071851027115a74d0b9be580005d45d22d6e228801b2705e2
ToppCelldroplet-Spleen-nan-3m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETX CEP350 ARHGDIB FCER2 HOOK1 ITSN2 MACF1

2.44e-07186102726f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-3|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

TTF2 MAN2B1 CRELD2 GCNT4 CNTN6 DST

2.08e-0616310260e8d3c98209fc98b86b841d69051cee9e276d837
ToppCellfacs-GAT-Fat-24m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC2 KIF20A EHF SEL1L3 STEAP1 CKMT1A

2.94e-061731026815ba48a9222ea09ba8005e2d2f7c5addf118ad1
ToppCellfacs-GAT-Fat-24m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC2 KIF20A EHF SEL1L3 STEAP1 CKMT1A

2.94e-06173102698e464d9e6d6b69421e9e4041b638b6825247f60
ToppCellfacs-GAT-Fat-24m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC2 KIF20A EHF SEL1L3 STEAP1 CKMT1A

2.94e-0617310263e6f0a08eddfd61871f7a85acccf6d539af6ebda
ToppCellfacs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNBP1 MAN2B1 CBFA2T3 ARHGDIB PRCP FERMT3

3.04e-061741026c52aed2ffe9c648e5f23e3459e2d331d6ca214e3
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 SFI1 CPS1 PKD1L2 DISP3 DMD

4.19e-0618410262cbed6462fea2622871bb7e49b0df3d984239281
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETX CBFA2T3 CEP350 ITSN2 MACF1 PLEKHM3

4.19e-0618410261154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 SFI1 CPS1 PKD1L2 DISP3 DMD

4.19e-061841026ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 SFI1 CPS1 PKD1L2 DISP3 DMD

4.19e-0618410262b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellFetal_29-31_weeks-Immune-T_lymphocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FNBP1 MGAT4A STAT4 ARHGDIB ERAP2 BIN2

5.35e-06192102669a2b04f03a1b82d067018379f7b8a116e954040
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FNBP1 TRPM2 CBFA2T3 STAT4 ARHGDIB BIN2

6.20e-06197102661ef3f417767c3f5296a26399da63e3e4f58faf8
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

TBC1D9B USE1 NUP98 SPG11 FANCA

6.55e-061141025670c9802a59b39241abf6f2c12a3d1844c7db5e5
ToppCellASK452-Epithelial|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

SELENBP1 ITPKC DST HOOK1 SUSD2 EHF

6.57e-061991026e8778d4d2bc7e15b4c7989a93e5808a76738df46
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FNBP1 MGAT4A STAT4 ARHGDIB BIN2 DTHD1

6.76e-062001026be9a43acc2f926b9433ab3f018b911b03896a924
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SETX STAT1 CEP350 KMT2C ITSN2 MACF1

6.76e-06200102612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FNBP1 MGAT4A STAT4 ARHGDIB BIN2 SERINC5

6.76e-062001026e0cec0a844b7c1f8edee4c005af27766754e470a
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRELD2 HOOK1 EHF LTA4H KAZN

1.39e-0513310255bf5e654653e2c340891f51e3f2a30441b7b6b2b
ToppCellRV-17._Lymphocyte|RV / Chamber and Cluster_Paper

TRPM2 STAT4 SEL1L3 BIN2 DTHD1

2.72e-051531025e1ea621184014415870e00d511386b8cc3e0833b
ToppCellfacs-Lung-Endomucin-24m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM2 ELP1 PKD1L2 ASPRV1 DTHD1

3.17e-0515810250ed844ab625351a46b74edddf082279ed1bae5c6
ToppCellfacs-Lung-Endomucin-24m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM2 ELP1 PKD1L2 ASPRV1 DTHD1

3.17e-051581025b3a810314e253b4fd0f578e759c36fdd21722934
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PNMA6F ARHGDIB TPRG1 BIN2 DTHD1

3.17e-051581025da060f5b61c7088f700d138b02ea596adacf7d60
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAN2B1 FANCA ARHGDIB BIN2 FERMT3

3.37e-051601025741e3b3f4ec5c77752da54746451f332435226e3
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGDIB NWD2 STEAP3 BIN2 FERMT3

3.58e-0516210259d6931619f5eb847c79d00ff5ae031fef30fd55c
ToppCellfacs-MAT-Fat-3m-Myeloid-macrophage|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNBP1 CBFA2T3 PIK3R6 PRCP PLEKHM3

3.79e-051641025b81498c3934e0d52bf0329dc745e02966f9d8613
ToppCelldroplet-Thymus-nan-3m-Myeloid-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM2 ITGA2B VWA7 PIK3R6 FCER2

4.02e-051661025c0af93db981dfd448abc7efcd257f3e5ff066aae
ToppCellfacs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYNC2H1 ECT2L SLC25A26 HOOK1 SLC35F2

4.50e-051701025d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCellBac-SEP-Myeloid-cDC1|Bac-SEP / Disease, Lineage and Cell Type

FNBP1 CBFA2T3 DST EHF DMD

4.89e-051731025f88269327441858ddb8c49b9dd619b76fd53b1da
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Lymphocytic-B_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA7 STAT4 KIF20A ARHGDIB FERMT3

4.89e-051731025a693772987f1baee533dd0bd285a3c7b5619a73b
ToppCellfacs-BAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGDIB FCER2 EHF ASPRV1 CKMT1A

5.16e-05175102546d6e319f8ca46592f23257800bcb6d228fffbbe
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GARIN1A ST3GAL3 DLG2 SERINC5 DMD

5.30e-051761025b4a23d8d1414434adeb237a96f28c825f1aebd77
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GARIN1A ST3GAL3 DLG2 SERINC5 DMD

5.30e-05176102566c9c6b59030f67e8d746a9c6930e50923f2ded1
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PKD1L2 KIF20A ITPKC SLC35F2 NUP160

5.45e-0517710251d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SERINC2 HOOK1 EHF STEAP1 CKMT1A

5.60e-051781025b89c4d015b44bf538aa39969ef8778877c8023f1
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SERINC2 HOOK1 EHF STEAP1 CKMT1A

5.60e-051781025fb8f8d95f6b08378fb42c4076ee040276faa296f
ToppCell356C-Lymphocytic-NK_cells-NK_cell_C|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SERINC2 LRIG2 PIK3R6

5.87e-053310235ce59ecc7f8432b14dc6cb9af56e1bf080e7d61f
ToppCellE18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA2B CBFA2T3 DLG2 BIN2 FERMT3

5.90e-051801025ca2a35bfb67347e47f511589a3d0f763e6664634
ToppCell10x3'2.3-week_14-16-Lymphocytic_NK-T_NK-ILC_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FNBP1 STAT4 HOOK1 EHF LGI1

5.90e-05180102527672ac6a02172a31851f18decb9acffa8f5a703
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MGAT4A GCNT4 STAT4 ATP6V0A4 SERINC5

5.90e-051801025f3d35b2ea78afef37a84232adf5e6e26712b618d
ToppCellE18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA2B CBFA2T3 DLG2 BIN2 FERMT3

5.90e-0518010254e9e8cde2919610c4ac0025b1c9819808048bc1d
ToppCellE18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA2B CBFA2T3 DLG2 BIN2 FERMT3

5.90e-051801025466381bf93c3da6a2a241daadb68e9aad2964eae
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SERINC2 DST EHF TPRG1 ASPRV1

6.06e-0518110256b43dcaeeb02ad5900772b6f16f1581847050e38
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

SFI1 STAT4 MACF1 SERINC5 EML1

6.06e-051811025f2315414e714ac86211546a935660c4be6e85f1b
ToppCellPND07-Epithelial-Epithelial_Airway-Basal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SERINC2 DST EHF TPRG1 ASPRV1

6.06e-051811025f50561fdacfb83ba85fe6476e7cbc2bad1ebc826
ToppCellfacs|World / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAT4A SERINC2 HOOK1 EHF CKMT1A

6.22e-05182102508f775135b451be709f5fc8e1cbcf63425794a2e
ToppCellFLU-Healthy-0|FLU / Virus stimulation, Condition and Cluster

CRELD2 STAT1 STAT4 ARHGDIB BIN2

6.38e-051831025058604ddb06b3bef131183d86b83b422dae8f6cb
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC2 GCNT4 EHF SEL1L3 SLC35F2

6.38e-0518310252df1611c8acccb2a6f233d3d68bd9df2381a7278
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

STAT1 CEP350 KMT2C DST ERAP2

6.38e-0518310258f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MGAT4A SFI1 GCNT4 STAT4 SERINC5

6.38e-051831025f2ef110bf29b1a8276ef216238363e542db262c1
ToppCellFLU-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

CRELD2 STAT1 STAT4 ARHGDIB BIN2

6.38e-0518310257a6f18246c39864479e114f698581f667fa9c600
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ITGA2B GCNT4 BIN2 KAZN FERMT3

6.55e-051841025ba65e3972b2b8d825a2c1a9d03d092cc1afad073
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HOOK1 ATP6V0A4 EHF LTA4H KAZN

6.55e-051841025ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

TTF2 SFI1 LRIG2 KMT2D MACF1

6.72e-051851025a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-NK_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAT4 ARHGDIB ATP6V0A4 BIN2 DTHD1

6.89e-051861025885aed2472cead81d60c9f3a28c0ff10eb449592
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FNBP1 STAT4 ARHGDIB BIN2 DTHD1

6.89e-0518610259d576dce2c5deefef1adda16c6da7055c8d57f8f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FNBP1 STAT4 ARHGDIB BIN2 DTHD1

6.89e-051861025bd3bd022b575d9b0ef90d50a5cb874085a827b77
ToppCellfacs-Trachea-nan-24m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 SELENBP1 SERINC2 EHF CKMT1A

6.89e-0518610256c06163d7315f1c71b15fe76f2e696bf3fa73b67
ToppCellfacs-Trachea-nan-24m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 SELENBP1 SERINC2 EHF CKMT1A

6.89e-05186102578e3b00eb347d1aa197671e31be9b0c6e4235760
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FNBP1 STAT4 ARHGDIB BIN2 DTHD1

6.89e-051861025924cc357b4c4ce8e9b05773bdab544f0b65474cc
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CRELD2 KIF20A SEL1L3 SLC35F2 CKMT1A

7.07e-05187102588d20f150df61ef0e3ee0c3e9895b094920c4b09
ToppCelldroplet-Spleen-nan-3m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETX ARHGDIB FCER2 ITSN2 MACF1

7.07e-05187102591c8e93bde0d1d1a4e324b0acf2afda00f4fb3bf
ToppCellILEUM-inflamed-(1)_CD8_Trm|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MGAT4A STAT4 TPRG1 SERINC5 DTHD1

7.07e-051871025a77d7ae44f47410bd92fb3aa0f44dce891752b63
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETX ARHGDIB FCER2 ITSN2 MACF1

7.07e-051871025382db691eb0b3e089e816bed3d6699cc2d4e1bda
ToppCellwk_15-18-Hematologic-Myeloid-Basophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TRPM2 ITGA2B CBFA2T3 PIK3R6 ITSN2

7.25e-0518810253638d85452de15a060146628fbbad9d2a36feb13
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CNTN6 HOOK1 EHF SEL1L3 DMD

7.25e-0518810250d86044bc340e3efb90d0022dd299873639d831c
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAT4 ARHGDIB FCER2 SLC35F2 FERMT3

7.43e-051891025039b1922c85aa749d6578583d9d41a4eef8a6ac4
ToppCellFetal_29-31_weeks-Immune-T_lymphocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FNBP1 MGAT4A STAT4 ARHGDIB ERAP2

7.62e-0519010252a8de1cf27a9ebc3825cf9e7a489ecd064dfc7f9
ToppCell(0)_T_CD4|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MGAT4A STAT4 ARHGDIB BIN2 FERMT3

7.81e-051911025ba289658777a2669fda9da9128e87adb60fd8430
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-leukocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GARIN1A SERINC2 ATP6V0A4 ASPRV1 CKMT1A

7.81e-051911025116fba9badea093e11f370996247cca0e4c02e8f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FNBP1 TRPM2 STAT4 PIK3R6 BIN2

7.81e-051911025468b5149d1533f03521844d3cce8633d44eb6ed4
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_mast/basophil_(18)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CBFA2T3 ARHGDIB FCER2 BIN2 FERMT3

7.81e-05191102514b11244c330cc4fe897253aaaf0df80caa01a55
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-NK_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAT4 ARHGDIB PIK3R6 BIN2 DTHD1

8.00e-051921025ec084cc4edb2ccd4e8fa646026ce89c39d7a0893
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SFI1 STAT4 KMT2C MACF1 SERINC5

8.00e-05192102547646d7e4990be85072987f92bf18d52f8da752e
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-ELP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FNBP1 CBFA2T3 ERAP2 MACF1 SERINC5

8.00e-05192102538ec82aa2ec4f2c0a843e83f7fe54f6b2483ca3d
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

MGAT4A STAT4 TPRG1 BIN2 DTHD1

8.00e-051921025ab88ea7723f0fa3b39611981c043445f27425404
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INSR SFI1 CEP350 MACF1 FERMT3

8.00e-0519210251ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MGAT4A STAT4 ARHGDIB TPRG1 BIN2

8.20e-051931025a77a6018a88291fb466cb9cd13eff4164b0cc8f1
ToppCellnormal_Pleural_Fluid-T/NK_cells-Naive_CD8+_T|normal_Pleural_Fluid / Location, Cell class and cell subclass

STAT4 ARHGDIB TPRG1 BIN2 DTHD1

8.20e-051931025828f11c9081df74faf3b788456991e1a0cf99900
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DYNC2H1 PPIL6 ECT2L DMD DTHD1

8.20e-051931025ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SFI1 STAT4 LRIG2 MACF1 SERINC5

8.20e-0519310259337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid|TCGA-Endometrium / Sample_Type by Project: Shred V9

CRELD2 SERINC2 SEL1L3 SERINC5 STEAP1

8.20e-0519310253465352298b1fc9d75af4c2fdd91ad7990cbc901
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAT4 PNMA6F ARHGDIB TPRG1 DTHD1

8.40e-0519410259344556b375fd9267652cdca57b2cbd50a878a1e
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-NK_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAT4 ARHGDIB PIK3R6 BIN2 DTHD1

8.40e-0519410253fe32e38c95135d152acb1624fec1623339e144a
ToppCellPCW_13-14-Epithelial-Epithelial_airway|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CNTN6 HOOK1 EHF SEL1L3 DMD

8.40e-0519410257b2b40a56eb9c7203ca50133b2da4fd8fdd4a5cf
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

MGAT4A STAT4 TPRG1 BIN2 DTHD1

8.40e-05194102568e9ad254fe94e2f59cf5c2b2ea3e1245cb85104
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

SPATA20 SPG11 KIFAP3 DST SUSD2

8.40e-05194102588db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

SPATA20 SPG11 KIFAP3 DST SUSD2

8.40e-051941025a71728202493d4858342ea2756ea281cd0d99a3a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STAT4 ARHGDIB BIN2 DTHD1 FERMT3

8.61e-051951025deadfbc25e922c967b96bdbed4e7b16ff77ee132
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD8-Trm/em_CD8|bone_marrow / Manually curated celltypes from each tissue

FNBP1 STAT4 ARHGDIB TPRG1 DTHD1

8.61e-051951025ed4e2275dac47cc9fb9c381e3f80fed0ce50b074
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

STAT1 STAT4 ARHGDIB ERAP2 SEL1L3

8.61e-051951025662b50a2aa97373bf343b88caace9717049c722a
ToppCellCV-Moderate-6|Moderate / Virus stimulation, Condition and Cluster

FNBP1 CEP350 KMT2C ERAP2 BIN2

8.61e-0519510252b8a72d7e755b9655c7a496000d10ff06e50862b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STAT4 ARHGDIB BIN2 DTHD1 FERMT3

8.61e-0519510257e3fc1fcaca99aa67d2992ac543ba59bcf477c1f
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NUP98 CRELD2 ERAP2 ITSN2 MACF1

8.82e-051961025ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MGAT4A STAT4 MACF1 BIN2 DTHD1

8.82e-051961025c100967851f037b3522130a9e2a4175ad593ecbc
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ELP1 ITGA2B PIK3R6 MACF1 BIN2

8.82e-0519610255bb8653af62334ded8aad48b24b64d7b54bc3cd5
ToppCellBronchial_Brush-Epithelial|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

SELENBP1 DYNC2H1 PPIL6 EHF DTHD1

9.03e-051971025272c7f4e582ef57564450540242b0db766b78328
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM2 CBFA2T3 STAT4 ARHGDIB BIN2

9.03e-0519710250523aec9713ae21e6b879aa98e07fa2576610d5f
ToppCellmild-dn_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MGAT4A SFI1 STAT1 SLC35F2 DTHD1

9.03e-05197102507a1f59c83b748825e0708cd1cc7b63a2cb856cc
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SELENBP1 CRELD2 HOOK1 EHF LTA4H

9.03e-051971025ad6f047d003c08413264f39a30ba0f7639a257cd
DrugGentamicine sulfate [1405-41-0]; Down 200; 2.6uM; PC3; HT_HG-U133A

TBC1D9B AMBRA1 TMEM80 STAT1 FANCA CEP350 DLG3 KAZN NUP160

2.70e-0720010195883_DN
DrugPNU-0293363 [326823-19-2]; Down 200; 10uM; PC3; HT_HG-U133A

TRPM2 MR1 ELP1 RABGAP1 CPS1 KIF20A ERAP2 DLG3

2.87e-0619810186568_DN
DrugMeropenem [96036-03-2]; Down 200; 10.4uM; PC3; HT_HG-U133A

USE1 SFI1 CINP TMEM80 CEP350 ZNF24 PARP16 KAZN

2.98e-0619910185824_DN
DrugTheobromine [83-67-0]; Down 200; 22.2uM; PC3; HT_HG-U133A

INSR MR1 ITGA2B CPS1 TMEM80 CEP350 ITPKC

2.48e-0519310176613_DN
DrugAzaguanine-8 [134-58-7]; Down 200; 26.2uM; MCF7; HT_HG-U133A

MR1 RABGAP1 TMEM80 KIFAP3 TRAPPC10 MACF1 DLG3

2.56e-0519410171670_DN
DrugFlumequine [42835-25-6]; Down 200; 15.4uM; PC3; HT_HG-U133A

MR1 TMEM80 ZNF24 DLG3 KAZN EML1 NUP160

2.56e-0519410175104_DN
DrugSkimmianine [83-95-4]; Down 200; 15.4uM; HL60; HT_HG-U133A

TBC1D9B CPS1 TMEM80 ERAP2 TRAPPC10 DLG1 KAZN

2.56e-0519410172504_DN
DrugThioguanosine [85-31-4]; Down 200; 12.6uM; PC3; HT_HG-U133A

SETX NUP98 CEP350 PARP16 TRAPPC10 EML1 NUP160

2.65e-0519510176643_DN
DrugMolsidomine [25717-80-0]; Down 200; 16.6uM; HL60; HG-U133A

TRPM2 NUP98 CINP STAT1 STAT4 TEFM MACF1

2.82e-0519710171711_DN
Drug(-)-Cinchonidine [485-71-2]; Down 200; 13.6uM; HL60; HG-U133A

TBC1D9B TRRAP STAT1 KIFAP3 PARP16 DLG1 SLC35F2

2.82e-0519710171780_DN
Drug(S)-propranolol hydrochloride [4199-10-4]; Down 200; 13.6uM; PC3; HT_HG-U133A

TBC1D9B CINP ARHGDIB TRAPPC10 DLG3 KAZN NUP160

2.92e-0519810176343_DN
DrugGuanabenz acetate [23256-50-0]; Down 200; 13.8uM; HL60; HG-U133A

NUP98 TRRAP STAT1 TEFM FANCA KIFAP3 MICALL2

3.01e-0519910172045_DN
Diseasebenign neoplasm (implicated_via_orthology)

DLG1 DLG2 DLG3

2.15e-0681013DOID:0060072 (implicated_via_orthology)
DiseaseKleefstra syndrome 2 (implicated_via_orthology)

KMT2C KMT2D

1.16e-0521012DOID:0080598 (implicated_via_orthology)
Diseaseglycine measurement, amino acid measurement

CPS1 PKD1L2

6.93e-0541012EFO_0005134, EFO_0009767
DiseaseMalignant neoplasm of breast

TBC1D9B DYNC2H1 NUP98 ELP1 STAT1 CNTN6 STAT4 EPG5 KMT2D HOOK1 ITSN2 MACF1 DMD

7.70e-05107410113C0006142
Disease2,3-dihydroxy-5-methylthio-4-pentenoate (DMTPA) measurement

SLC25A26 CPS1

1.72e-0461012EFO_0800111
Diseaseinterleukin 17 measurement

AMBRA1 FANCA NUP160

4.98e-04451013EFO_0008174
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

FANCA KMT2C KMT2D

4.98e-04451013DOID:3748 (is_implicated_in)
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

DLG1 DLG2 DLG3

6.40e-04491013DOID:0060037 (implicated_via_orthology)
Diseasesurvival time, lung adenocarcinoma

NWD2 DLG2

7.49e-04121012EFO_0000571, EFO_0000714
Diseaseneutrophil count

DYNC2H1 SLC25A26 CPS1 CBFA2T3 VWA7 FANCA LRIG2 KIFAP3 FCER2 ERAP2 ITSN2 DTHD1 NUP160

8.71e-04138210113EFO_0004833
DiseaseSjogren's Syndrome

STAT4 ITSN2

8.83e-04131012C1527336
DiseaseSicca Syndrome

STAT4 ITSN2

8.83e-04131012C0086981
Diseaserevision of total hip arthroplasty

ICE1 VWA7

1.03e-03141012EFO_0020973
Diseaseasthma (biomarker_via_orthology)

STAT1 STAT4 LTA4H

1.10e-03591013DOID:2841 (biomarker_via_orthology)
Diseasepancreas fat measurement

CBFA2T3 PLEKHM3

1.18e-03151012EFO_0600049
Diseaseglycine measurement

INSR CPS1 PKD1L2 PLEKHM3

1.28e-031371014EFO_0009767
Diseasefish consumption measurement

NOX3 DLG2 EML1

1.39e-03641013EFO_0010139
Diseasecarcinoma (implicated_via_orthology)

DLG1 DLG2 DLG3

1.39e-03641013DOID:305 (implicated_via_orthology)
DiseaseAmyotrophic lateral sclerosis

SETX SPG11

1.53e-03171012cv:C0002736
Diseaseamyotrophic lateral sclerosis

STK36 C4orf36 KIFAP3 SUSD2

1.58e-031451014MONDO_0004976
Diseasephospholipids:total lipids ratio, intermediate density lipoprotein measurement

SPG11 CPS1 MACF1

1.59e-03671013EFO_0008595, EFO_0020946
Diseasejuvenile idiopathic arthritis

FNBP1 STAT4 ERAP2

2.12e-03741013EFO_0002609
Diseaseprostate adenocarcinoma (is_implicated_in)

INSR STAT1

2.12e-03201012DOID:2526 (is_implicated_in)
Diseasecancer (implicated_via_orthology)

DST DLG1 MACF1 DLG2 DLG3

2.32e-032681015DOID:162 (implicated_via_orthology)
DiseaseOvarian Serous Adenocarcinoma

STK36 TRRAP

2.80e-03231012C1335177
Diseasebrain measurement, neuroimaging measurement

MR1 RABGAP1 SLC25A26 CHRNB3 MACF1 DLG2 EML1

2.87e-035501017EFO_0004346, EFO_0004464
DiseaseParkinson Disease

TRPM2 INSR FCER2

3.14e-03851013C0030567
Diseasepallidum volume

CHRNB3 DLG2

3.31e-03251012EFO_0006933
DiseaseTEMPS-A questionnaire

DYNC2H1 SLC35F2

3.31e-03251012EFO_0004783

Protein segments in the cluster

PeptideGeneStartEntry
VEEEAKLFLWWHQVL

EPG5

2411

Q9HCE0
TTNVWLKQEWTDHKL

CHRNB3

76

Q05901
VQLQELLHHWVLWSA

DISP3

711

Q9P2K9
WENVSRHLKAWDDNL

ERVK13-1

396

Q9NX77
DILHVINASDDEWWQ

DLG1

611

Q12959
ISHWFDLWTNKQRQE

ECT2L

31

Q008S8
QWKRLHLSLQELLVW

DMD

2806

P11532
VNTEWEKLNLHSADW

DMD

2911

P11532
LLLIATANEIHFWDW

AMBRA1

151

Q9C0C7
HEELKAIVWNNDLLW

BIN2

96

Q9UBW5
LEQLSENDDARKLWW

NWD2

516

Q9ULI1
KHDIITVLEQQENWW

ITSN2

921

Q9NZM3
ERVKSWADNLWTHQN

ITPKC

186

Q96DU7
VDQILKWIEQWIKDH

AK6

156

Q9Y3D8
LVTNKTWDHFWLNEG

LTA4H

306

P09960
WGELLSKWHLNLNVR

RABGAP1

541

Q9Y3P9
IDWLLDHILWVKVCN

MGAT4A

321

Q9UM21
LSEELVESWWFHKQQ

CRELD1

111

Q96HD1
LWEWAIFVLLHIDNS

NUP98

1561

P52948
HWVAKAWLNDIGLSQ

KAZN

526

Q674X7
NLDLDLWVHLNCALW

KMT2C

4421

Q8NEZ4
LWLHNKLGATDELWA

NELFA

11

Q9H3P2
KQELLEALLAWLQWA

DST

7036

Q03001
WFWLIHEKQLLLRQE

MICALL2

781

Q8IY33
SWLEDAKDMLQLWCH

PNMA6F

271

A0A0J9YX94
ALEWHLLQRQLQLQW

FAM205A

521

Q6ZU69
ALEWHLLQRQLQLQW

FAM205BP

251

Q63HN1
LLLLWHWDTTQSLKQ

FCER2

41

P06734
DIQHLKDWISETWVN

PRCP

271

P42785
DLLWNADSSVLAVWL

ELP1

291

O95163
RQLWDWSKHNLTITQ

INSR

436

P06213
ALDWGQKLWEVVHAA

PLEKHM3

296

Q6ZWE6
EWAEEWKHLNNLLNC

CBFA2T3

391

O75081
DALDLQKWAHEVWDI

PPIL6

101

Q8IXY8
LWHQLHVNTKSLISW

MACF1

946

Q9UPN3
QKHISQDREWWIGLT

PKD1L2

76

Q7Z442
GDNHKRAWDLVSWIL

PARP16

76

Q8N5Y8
IQVHTTEDWAWKKQL

DYNC2H1

1616

Q8NCM8
LNVIKEAEAQLWWAA

CFAP298

181

P57076
NHWLATKSLGQWLQE

CPS1

141

P31327
HQKWIWTHDNIISKE

ICE1

2126

Q9Y2F5
AELRWLIKDGHWFAN

GCNT4

396

Q9P109
DDKQDHLSWEWNLSI

ARHGDIB

181

P52566
ELWDQFDNLEKHTQW

FNBP1

6

Q96RU3
WEWLQHLLDTNQLDA

EHF

56

Q9NZC4
WKIQSSLLLEAVWHL

FANCA

171

O15360
LVHNAAEELWKWKEL

CEP350

2926

Q5VT06
AWKLTNSKLCLNWEH

CNTN6

911

Q9UQ52
DILHVINASDDEWWQ

DLG3

531

Q92796
ALWDNLLHWLAEELS

DTHD1

676

Q6ZMT9
WELNKANLTWSVKHD

MAN2B1

361

O00754
LAWDFVRENWTHLLK

ERAP2

871

Q6P179
DILHVINASDDEWWQ

DLG2

566

Q15700
HVLSVWDWQKEEKLA

EML1

351

O00423
VLHQIDAAWFNESWL

HOOK1

46

Q9UJC3
WDIALLAKTWSTNLA

C4orf36

26

Q96KX1
AQEEHLEAWWLQLKS

CRELD2

96

Q6UXH1
LWESLKALWSWRQDH

SLC25A26

161

Q70HW3
IQSEKFRWHNSQWLE

KIFAP3

671

Q92845
WHNNEKSFLIWVNEE

CKMT1A

251

P12532
WLAVDNVAHTIKQAW

MR1

151

Q95460
HSLWEQEDWNEHLLQ

GARIN1A

281

Q6NXP2
QWKEEQKLEAHSDWV

SEC13

201

P55735
KHRALSLQVQAWSQW

SFI1

246

A8K8P3
KDVQALWTNDHALAW

SUSD2

261

Q9UGT4
WNVKWEENLLHAVAK

SEL1L3

186

Q68CR1
QWLEKQDWEHAANDV

STAT1

36

P42224
AHFLLWQALVLWADW

TMEM80

176

Q96HE8
LWADWALSATLLALH

TMEM80

186

Q96HE8
TFHLWTGEEQLWKEL

PIK3R6

286

Q5UE93
NKKCLHLLWVSSQQW

SETX

471

Q7Z333
SAWKLHLLQWEEDSN

ST3GAL3

26

Q11203
WDWQRHEIVQTLSLK

SELENBP1

231

Q13228
AWAHLDRKLTVLDWQ

TEFM

181

Q96QE5
WQHWNVLEKTEEAEK

ITGA2B

141

P08514
DIASIHWDWKIALLF

SLC35F2

251

Q8IXU6
IWALWHDAENQTVVK

NUP160

406

Q12769
WDENQALHIALHWDE

NOX3

481

Q9HBY0
WDAKEQVCWHLANQL

STK36

676

Q9NRP7
TIHALIFAWNKWIDI

STEAP1

266

Q9UHE8
KEITKHWEWLENNLL

TBC1D9B

81

Q66K14
HWEWLENNLLQTLSI

TBC1D9B

86

Q66K14
WLHSFEVINDLNHWD

ASPRV1

116

Q53RT3
NAADWHNLILKWETL

CINP

26

Q9BW66
SFWLNEDLIWHQKIK

ZNF37A

126

P17032
EDLIWHQKIKNWEQS

ZNF37A

131

P17032
DHRIVLNWALWWDQL

SPG11

846

Q96JI7
RLEQHTQKSVNWLLW

USE1

221

Q9NZ43
AVENQLKWASWELHS

ZNF24

171

P17028
VLANKSHLWVEEEVW

STEAP3

341

Q658P3
WIHVQDAEEAWKLLK

KIF20A

346

O95235
RHLLAQWIENQDWEA

STAT4

31

Q14765
NWDHQLKLAVAWNRV

TRPM2

451

O94759
WLEWALRLQDTQDKL

SPATA20

596

Q8TB22
LLLVEFAHKWNKNWT

SERINC5

171

Q86VE9
ETIQGFWLLTKIDHW

TPRG1

91

Q6ZUI0
FWLLTKIDHWNNEKE

TPRG1

96

Q6ZUI0
DAKLRAWAGQLHQLW

TREH

121

O43280
HACELWIGEKEQWLL

SPTBN4

891

Q9H254
EQINRKQDWSDHAIW

FERMT3

51

Q86UX7
DHAIWWEQKRQWLLQ

FERMT3

61

Q86UX7
WEQKRQWLLQTHWTL

FERMT3

66

Q86UX7
QEAAANWHSWLIKVQ

ATP6V0A4

286

Q9HBG4
WQNVLKAHSSVDWLI

TRAPPC10

111

P48553
AHLELNESAWGRLWL

VWA7

776

Q9Y334
EDHWIRCSKELNQWE

TRRAP

2821

Q9Y4A5
VLLIDFAHSWNQRWL

SERINC2

176

Q96SA4
LLHQKQALAWLLWRE

TTF2

571

Q9UNY4
NLDLDLWVHLNCALW

KMT2D

5051

O14686
LKWLVEWLGHTNATV

LGI1

181

O95970
LKWLLQWLVDNNFQH

LRIG2

451

O94898