Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	spinal cord association neuron differentiation	WNT3A PAX7 MDGA1	1.11e-05	14	66	3	GO:0021527
GeneOntologyBiologicalProcess	dorsal spinal cord development	WNT3A PAX7 MDGA1	4.61e-05	22	66	3	GO:0021516
Domain	Protein_Kinase_C_mu-related	PRKD2 PRKD1	3.68e-05	3	66	2	IPR015727
Domain	HP	SVIL ABLIM3	3.40e-04	8	66	2	PS51089
Domain	-	SVIL ABLIM3	3.40e-04	8	66	2	1.10.950.10
Domain	VHP	SVIL ABLIM3	3.40e-04	8	66	2	PF02209
Domain	Villin_headpiece	SVIL ABLIM3	3.40e-04	8	66	2	IPR003128
Domain	VHP	SVIL ABLIM3	3.40e-04	8	66	2	SM00153
Domain	C1_1	PRKD2 ARHGEF28 PRKD1	1.08e-03	57	66	3	PF00130
Domain	VitD_rcpt	NR2C1 NR1H2	1.09e-03	14	66	2	IPR000324
Domain	PTPc_motif	MTMR7 PTPN18 PTPN20	1.19e-03	59	66	3	SM00404
Domain	Tyr_Pase_cat	MTMR7 PTPN18 PTPN20	1.19e-03	59	66	3	IPR003595
Domain	ZF_DAG_PE_1	PRKD2 ARHGEF28 PRKD1	1.51e-03	64	66	3	PS00479
Domain	ZF_DAG_PE_2	PRKD2 ARHGEF28 PRKD1	1.51e-03	64	66	3	PS50081
Domain	C1	PRKD2 ARHGEF28 PRKD1	1.57e-03	65	66	3	SM00109
Domain	PE/DAG-bd	PRKD2 ARHGEF28 PRKD1	1.65e-03	66	66	3	IPR002219
Domain	Tyr_Pase_AS	MTMR7 PTPN18 PTPN20	2.20e-03	73	66	3	IPR016130
Domain	DAG/PE-bd	PRKD2 PRKD1	2.47e-03	21	66	2	IPR020454
Domain	TYR_PHOSPHATASE_1	MTMR7 PTPN18 PTPN20	3.50e-03	86	66	3	PS00383
Domain	TYR_PHOSPHATASE_2	MTMR7 PTPN18 PTPN20	3.62e-03	87	66	3	PS50056
Domain	TYR_PHOSPHATASE_dom	MTMR7 PTPN18 PTPN20	3.62e-03	87	66	3	IPR000387
Domain	-	MTMR7 PTPN18 PTPN20	4.23e-03	92	66	3	3.90.190.10
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RBM15 MTMR7 WASHC5 CALR BCAS2 SVIL PSMB2 PPP6R1 PTPN18 PTPN20 CIC CLCC1	2.09e-06	1049	74	12	27880917
Pubmed	Both the establishment and maintenance of neuronal polarity require the activity of protein kinase D in the Golgi apparatus.	PRKD2 PRKD1	4.47e-06	2	74	2	18753385
Pubmed	Functional redundancy of protein kinase D1 and protein kinase D2 in neuronal polarity.	PRKD2 PRKD1	4.47e-06	2	74	2	25639845
Pubmed	The role of PKD in cell polarity, biosynthetic pathways, and organelle/F-actin distribution.	PRKD2 PRKD1	4.47e-06	2	74	2	24492625
Pubmed	Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells.	PRKD2 PRKD1	4.47e-06	2	74	2	20819079
Pubmed	Differential expression of PKD1 and PKD2 in gastric cancer and analysis of PKD1 and PKD2 function in the model system.	PRKD2 PRKD1	4.47e-06	2	74	2	22217708
Pubmed	Genomic analysis of recurrences and high-grade forms of polymorphous adenocarcinoma.	PRKD2 PRKD1	4.47e-06	2	74	2	30843621
Pubmed	Protein kinase D2 induces invasion of pancreatic cancer cells by regulating matrix metalloproteinases.	PRKD2 PRKD1	4.47e-06	2	74	2	24336522
Pubmed	Visualization of PAX7 protein dynamics in muscle satellite cells in a YFP knock-in-mouse line.	LAMA2 PAX7	4.47e-06	2	74	2	30139390
Pubmed	Functional and therapeutic significance of protein kinase D enzymes in invasive breast cancer.	PRKD2 PRKD1	1.34e-05	3	74	2	26253275
Pubmed	Expression of the protein kinase D (PKD) family during mouse embryogenesis.	PRKD2 PRKD1	1.34e-05	3	74	2	16377259
Pubmed	Protein kinase D1/2 is involved in the maturation of multivesicular bodies and secretion of exosomes in T and B lymphocytes.	PRKD2 PRKD1	1.34e-05	3	74	2	26045048
Pubmed	A Novel Conserved Domain Mediates Dimerization of Protein Kinase D (PKD) Isoforms: DIMERIZATION IS ESSENTIAL FOR PKD-DEPENDENT REGULATION OF SECRETION AND INNATE IMMUNITY.	PRKD2 PRKD1	1.34e-05	3	74	2	27662904
Pubmed	Inhibition of protein kinase D by CID755673 promotes maintenance of the pluripotency of embryonic stem cells.	PRKD2 PRKD1	1.34e-05	3	74	2	32747433
Pubmed	Lack of PRKD2 and PRKD3 kinase domain somatic mutations in PRKD1 wild-type classic polymorphous low-grade adenocarcinomas of the salivary gland.	PRKD2 PRKD1	1.34e-05	3	74	2	26426580
Pubmed	Protein kinase D in vascular biology and angiogenesis.	PRKD2 PRKD1	1.34e-05	3	74	2	21488147
Pubmed	Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells.	PRKD2 PRKD1	1.34e-05	3	74	2	20497126
Pubmed	The RNA-binding protein Rbfox1 regulates splicing required for skeletal muscle structure and function.	LAMA2 PAX7	1.34e-05	3	74	2	25575511
Pubmed	The protein scaffold NHERF-1 controls the amplitude and duration of localized protein kinase D activity.	PRKD2 PRKD1	1.34e-05	3	74	2	19581308
Pubmed	Overexpression of the cytotoxic T cell (CT) carbohydrate inhibits muscular dystrophy in the dyW mouse model of congenital muscular dystrophy 1A.	LAMA2 B4GALNT2	1.34e-05	3	74	2	17591965
Pubmed	Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart.	PRKD2 PRKD1	1.34e-05	3	74	2	38419169
Pubmed	Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network.	PRKD2 PRKD1	2.67e-05	4	74	2	14743217
Pubmed	Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop.	PRKD2 PRKD1	2.67e-05	4	74	2	28428613
Pubmed	Survival kinase genes present prognostic significance in glioblastoma.	ULK4 CDCP1	2.67e-05	4	74	2	26956052
Pubmed	HLA-F is a predominantly empty, intracellular, TAP-associated MHC class Ib protein with a restricted expression pattern.	CALR TAP1	2.67e-05	4	74	2	10605026
Pubmed	Structural mechanism of ER retrieval of MHC class I by cowpox.	CALR TAP1	2.67e-05	4	74	2	23209377
Pubmed	The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.	NBAS CALR CDCP1 TAP1 CLCC1	3.81e-05	176	74	5	28692057
Pubmed	Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation.	PRKD2 PRKD1	4.45e-05	5	74	2	15623513
Pubmed	Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche.	LAMA2 PAX7	4.45e-05	5	74	2	26440893
Pubmed	Protein kinase D regulates RhoA activity via rhotekin phosphorylation.	PRKD2 PRKD1	4.45e-05	5	74	2	22228765
Pubmed	Pax7, Pax3 and Mamstr genes are involved in skeletal muscle impaired regeneration of dy2J/dy2J mouse model of Lama2-CMD.	LAMA2 PAX7	4.45e-05	5	74	2	31348492
Pubmed	PKD, PKD2, and p38 MAPK mediate Hsp27 serine-82 phosphorylation induced by neurotensin in pancreatic cancer PANC-1 cells.	PRKD2 PRKD1	4.45e-05	5	74	2	17570131
Pubmed	The zinc-finger transcription factor, early growth response 3, mediates VEGF-induced angiogenesis.	PRKD2 PRKD1	6.66e-05	6	74	2	18059339
Pubmed	Inhibition of major histocompatibility complex-I antigen presentation by sarbecovirus ORF7a proteins.	CALR TAP1	6.66e-05	6	74	2	36136978
Pubmed	Testicular receptor 2, Nr2c1, is associated with stem cells in the developing olfactory epithelium and other cranial sensory and skeletal structures.	NR2C1 PAX7	6.66e-05	6	74	2	26712358
Pubmed	RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix.	IGF1R PRKD1	9.31e-05	7	74	2	11884618
Pubmed	Recruitment of MHC class I molecules by tapasin into the transporter associated with antigen processing-associated complex is essential for optimal peptide loading.	CALR TAP1	9.31e-05	7	74	2	11823531
Pubmed	Nucleotide binding by TAP mediates association with peptide and release of assembled MHC class I molecules.	CALR TAP1	9.31e-05	7	74	2	10508608
Pubmed	FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration.	LONRF1 PPP6R1 VWDE	1.00e-04	42	74	3	29348145
Pubmed	Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase.	PRKD2 PRKD1	1.24e-04	8	74	2	18440775
Pubmed	Interactions formed by individually expressed TAP1 and TAP2 polypeptide subunits.	CALR TAP1	1.24e-04	8	74	2	12047747
Pubmed	Point mutations in the alpha 2 domain of HLA-A2.1 define a functionally relevant interaction with TAP.	CALR TAP1	1.59e-04	9	74	2	8805302
Pubmed	Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing.	CALR TAP1	1.59e-04	9	74	2	17055437
Pubmed	Redundant type II cadherins define neuroepithelial cell states for cytoarchitectonic robustness.	WNT3A PAX7	1.99e-04	10	74	2	33060832
Pubmed	ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly.	CALR TAP1	1.99e-04	10	74	2	9545232
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CUL3 CELSR2 PELP1 UBE2V1 SVIL PRKD1 PPP6R1 ABLIM3 CDH10	2.03e-04	963	74	9	28671696
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	NBAS PELP1 UBE2V1 CALR BCAS2 PSMB2 PPP6R1 OGDH TAP1 JMY CLCC1	2.25e-04	1440	74	11	30833792
Pubmed	MEMO1 drives cranial endochondral ossification and palatogenesis.	MEMO1 TBX22	2.43e-04	11	74	2	26746790
Pubmed	Msx1 is required for dorsal diencephalon patterning.	WNT3A PAX7	2.43e-04	11	74	2	12874124
Pubmed	Hesr1 and Hesr3 are essential to generate undifferentiated quiescent satellite cells and to maintain satellite cell numbers.	LAMA2 PAX7	2.43e-04	11	74	2	21989910
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	CUL3 PRKD2 RBM15 ERP44 SYTL4 USP32 PPP6R1 OGDH DEDD	2.79e-04	1005	74	9	19615732
Pubmed	Simulated Microgravity Promotes Cell Apoptosis Through Suppressing Uev1A/TICAM/TRAF/NF-κB-Regulated Anti-Apoptosis and p53/PCNA- and ATM/ATR-Chk1/2-Controlled DNA-Damage Response Pathways.	UBE2V1 CHEK2	2.91e-04	12	74	2	26887372
Pubmed	Congenital hydrocephalus in genetically engineered mice.	CELSR2 ULK4	2.91e-04	12	74	2	21746835
Pubmed	Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.	SPDYE17 SPDYE3	3.43e-04	13	74	2	15611625
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	RBM15 PELP1 CALR CHD6 PPP6R1	3.45e-04	282	74	5	23667531
Pubmed	Inhibition of floor plate differentiation by Pax3: evidence from ectopic expression in transgenic mice.	WNT3A PAX7	4.00e-04	14	74	2	8756299
Pubmed	Confirming genes influencing risk to cleft lip with/without cleft palate in a case-parent trio study.	ABCA4 PAX7	4.00e-04	14	74	2	23512105
Pubmed	Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.	CELSR2 MDGA1	4.61e-04	15	74	2	20473291
Pubmed	Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis.	ARHGEF28 UBE2V1	4.61e-04	15	74	2	23892723
Pubmed	Genetic evidence that Celsr3 and Celsr2, together with Fzd3, regulate forebrain wiring in a Vangl-independent manner.	CELSR2 WNT3A	4.61e-04	15	74	2	25002511
Pubmed	Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation.	TBX22 CUL3 OCEL1 CPED1 DEDD	4.93e-04	305	74	5	21244100
Pubmed	Genetic predictors of fibrin D-dimer levels in healthy adults.	ABCA4 ARHGEF28	5.26e-04	16	74	2	21502573
Pubmed	Signalling through the type 1 insulin-like growth factor receptor (IGF1R) interacts with canonical Wnt signalling to promote neural proliferation in developing brain.	IGF1R WNT3A	5.26e-04	16	74	2	22625652
Pubmed	Armc5 deletion causes developmental defects and compromises T-cell immune responses.	CUL3 TTF1	5.95e-04	17	74	2	28169274
Pubmed	Characterization of a new family of cyclin-dependent kinase activators.	SPDYE17 SPDYE3	5.95e-04	17	74	2	15574121
Pubmed	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.	WASHC5 BCAS2 SVIL PSMB2	6.02e-04	180	74	4	24104479
Pubmed	Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.	CUL3 ERP44 ACAT1 CALR PSMB2 CHEK2	6.60e-04	495	74	6	28581483
Pubmed	Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.	PRKD1 PAX7	6.68e-04	18	74	2	23669352
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	ERP44 ACAT1 CALR SVIL CLHC1 CLCC1	7.17e-04	503	74	6	36217030
Pubmed	Migration Speed of Cajal-Retzius Cells Modulated by Vesicular Trafficking Controls the Size of Higher-Order Cortical Areas.	CALR WNT3A	7.46e-04	19	74	2	26387718
Pubmed	A role for En-2 and other murine homologues of Drosophila segment polarity genes in regulating positional information in the developing cerebellum.	WNT3A PAX7	7.46e-04	19	74	2	8575294
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	CUL3 NBAS SYTL4 WASHC5 CALR BCAS2 SVIL CHEK2 TSEN2	7.59e-04	1155	74	9	20360068
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	ERGIC1 RBM15 PELP1 WASHC5 BCAS2	8.04e-04	340	74	5	24332808
Pubmed	Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.	ERGIC1 MTMR7 ARHGEF28 ERP44 CALR BCAS2 PTPN18 PTPN20	8.11e-04	931	74	8	27432908
Pubmed	Evolutionarily conserved regulators of tau identify targets for new therapies.	ERP44 ACAT1 UBE2V1 CALR PSMB2 CLCC1	8.18e-04	516	74	6	36610398
Pubmed	Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci.	ABCA4 PAX7	8.28e-04	20	74	2	22863734
Pubmed	CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex.	CUL3 UBE2V1	9.14e-04	21	74	2	12481031
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	CUL3 ERP44 PELP1 CALR PPP6R1 OGDH	9.67e-04	533	74	6	25544563
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	ERGIC1 IGF1R ERP44 CELSR2 CALR SVIL PPP6R1 TAP1 CLCC1	9.99e-04	1201	74	9	35696571
Pubmed	Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.	LAMA2 PAX7	1.00e-03	22	74	2	28334989
Pubmed	Nuclear receptors in Leydig cell gene expression and function.	NR2C1 NR1H2	1.00e-03	22	74	2	20375256
Pubmed	Lamina-associated polypeptide 1 is dispensable for embryonic myogenesis but required for postnatal skeletal muscle growth.	IGF1R PAX7	1.00e-03	22	74	2	27798115
Pubmed	Homozygous Ft embryos are affected in floor plate maintenance and ventral neural tube patterning.	WNT3A PAX7	1.00e-03	22	74	2	15789444
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	PRKD2 MTMR7 ERP44 CALR PSMB2 PPP6R1 PTPN18 PTPN20	1.08e-03	974	74	8	28675297
Pubmed	Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46.	ERGIC1 ERP44	1.20e-03	24	74	2	15308636
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	TBX22 CUL3 PRKD2 IGF1R PRKD1	1.20e-03	372	74	5	22939624
Pubmed	The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.	NBAS CALR LONRF1 PSMB2	1.38e-03	225	74	4	25277244
Pubmed	DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors.	LRRTM2 MDGA1	1.40e-03	26	74	2	34848499
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RBM15 ERP44 PELP1 ACAT1 CALR BCAS2 SVIL TAP1	1.49e-03	1024	74	8	24711643
Pubmed	A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.	MEMO1 CUL3 ERGIC1 ERP44 CLCC1	1.51e-03	392	74	5	33144569
Pubmed	ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.	CHEK2 CHD6	1.51e-03	27	74	2	17525332
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	RBM15 VPS13D BCAS2 WNT3A PSMB2 CTRC PAX7 DEDD	1.55e-03	1031	74	8	16710414
Pubmed	Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.	CELSR2 ACAT1	1.75e-03	29	74	2	20167577
Pubmed	Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation.	PAX7 OGDH	1.87e-03	30	74	2	31693883
Pubmed	The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway.	CALR ULK4	2.00e-03	31	74	2	29099309
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	NR2C1 ERP44 CHD6 PPP6R1 CIC	2.00e-03	418	74	5	34709266
Pubmed	Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.	IGF1R RAD54B CHEK2	2.02e-03	117	74	3	19124506
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	IGF1R CHD6 PTPN18 DNAH7 PTPN20	2.04e-03	420	74	5	28065597
Pubmed	Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes.	ABCA4 ADAMTS3	2.13e-03	32	74	2	21546767
Interaction	CDHR4 interactions	PRKD2 CELSR2 PPP6R1 TSEN2 VWDE	2.87e-06	68	66	5	int:CDHR4
Cytoband	Ensembl 112 genes in cytogenetic band chr7q11	SPDYE11 SPDYE17 SPDYE10 SPDYE13 SPDYE15 SPDYE8 SPDYE9 SPDYE12 SPDYE14	8.66e-10	271	77	9	chr7q11
Cytoband	7q11.23	SPDYE10 SPDYE8 SPDYE9 SPDYE14	2.25e-05	97	77	4	7q11.23
Cytoband	Ensembl 112 genes in cytogenetic band chr1p13	RBM15 CELSR2 BCAS2 CLCC1	4.51e-04	211	77	4	chr1p13
GeneFamily	Speedy/RINGO cell cycle regulator family	SPDYE3 SPDYE8 SPDYE9	3.80e-06	12	48	3	756
GeneFamily	Protein tyrosine phosphatases, non-receptor type	PTPN18 PTPN20	1.03e-03	18	48	2	812
Disease	Respiratory Depression	IGF1R IFT80	4.02e-04	13	68	2	C0235063
Disease	Respiratory Insufficiency	IGF1R IFT80	4.02e-04	13	68	2	C0035229
Disease	Respiratory Failure	IGF1R IFT80	4.02e-04	13	68	2	C1145670
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	CELSR2 ADAMTS3	4.68e-04	14	68	2	EFO_0004611, EFO_0008589
Disease	Prostatic Neoplasms	CUL3 ERP44 CALR CHEK2 CHD6 ZBED1 TAP1	5.38e-04	616	68	7	C0033578
Disease	Malignant neoplasm of prostate	CUL3 ERP44 CALR CHEK2 CHD6 ZBED1 TAP1	5.38e-04	616	68	7	C0376358
Disease	hydrocephalus (implicated_via_orthology)	CELSR2 ULK4	8.72e-04	19	68	2	DOID:10908 (implicated_via_orthology)
Disease	diastolic blood pressure, systolic blood pressure	ZNF800 PELP1 ADAMTS3 SVIL ULK4 CHD6 DNAH7	8.81e-04	670	68	7	EFO_0006335, EFO_0006336
Disease	cortical thickness	VPS13D IGF1R ABCA4 ADAMTS3 WNT3A LAMA2 PAX7 CPED1 PTPN20	9.99e-04	1113	68	9	EFO_0004840
Disease	Low Grade Lymphoma (neoplasm)	RAD54B CHEK2	1.07e-03	21	68	2	C0079747
Disease	Lymphoma, Intermediate-Grade	RAD54B CHEK2	1.07e-03	21	68	2	C0079741
Disease	High Grade Lymphoma (neoplasm)	RAD54B CHEK2	1.07e-03	21	68	2	C0079740
Disease	Diffuse Mixed-Cell Lymphoma	RAD54B CHEK2	1.07e-03	21	68	2	C0079757
Disease	Lymphoma, Undifferentiated	RAD54B CHEK2	1.07e-03	21	68	2	C0024306
Disease	Reticulosarcoma	RAD54B CHEK2	1.07e-03	21	68	2	C0024302
Disease	Lymphoma, Mixed-Cell	RAD54B CHEK2	1.07e-03	21	68	2	C0024304
Disease	Lymphoma, Diffuse	RAD54B CHEK2	1.07e-03	21	68	2	C3714542
Disease	Colorectal Carcinoma	TBX22 ABCA4 CALR BCAS2 CHEK2 B4GALNT2 PRKD1	1.15e-03	702	68	7	C0009402
Disease	Lymphoma, Non-Hodgkin, Familial	RAD54B CHEK2	1.17e-03	22	68	2	C4721532
Disease	Lymphoma, Small Noncleaved-Cell	RAD54B CHEK2	1.17e-03	22	68	2	C0079770
Disease	level of Sphingomyelin (d42:2) in blood serum	PELP1 ADAMTS3	2.04e-03	29	68	2	OBA_2045183
Disease	D dimer measurement	ABCA4 ARHGEF28	2.18e-03	30	68	2	EFO_0004507
Disease	level of Sphingomyelin (d38:1) in blood serum	PELP1 ADAMTS3	2.18e-03	30	68	2	OBA_2045180

Protein segments in the cluster

Peptide	Gene	Start	Entry
RYKDVLPYDQTRVIL	PTPN18	61	Q99952
LLYTDRYPEEKSVIT	TTF1	566	Q15361
KSIYEVQRPDLISYE	ABLIM3	316	O94929
TLETRYRKPFYTIDL	ERVK-18	246	O42043
TLITYKLTIYREDRP	CPED1	656	A4D0V7
IDSTRKDPIYSYDRR	ABCA4	351	P78363
RSIREYYPDLTVIVA	B4GALNT2	341	Q8NHY0
RKEERVEYYIPGSTT	CDCP1	276	Q9H5V8
PLDYETTKEYTLRVR	CELSR2	461	Q9HCU4
PDLVDKYLEETSIRY	DEDD	111	O75618
KYLEETSIRYVTPRA	DEDD	116	O75618
DEPLLKRTDKYRTYS	CHEK2	126	O96017
RELEESKYQYSEPRL	AMPD3	426	Q01432
SSYRKIYEEPIILSR	RAD54B	486	Q9Y620
YDRPLKIEAVYVSRR	RBM15	241	Q96T37
ITKTYPDDTYRLSRL	NR2C1	536	P13056
LKYPPVSSERERSRY	OCEL1	151	Q9H607
YPDIYTREELAQRTK	PAX7	241	P23759
YPVLVERILQYTKER	ARHGEF28	1006	Q8N1W1
YILTDLRVPHSYEVR	MDGA1	706	Q8NFP4
RYYKEIPLSEILSLE	PRKD1	461	Q15139
ATTYRDPTTEYTKRI	LRRTM2	371	O43300
RLISEKRDEVVYYDT	JMY	561	Q8N9B5
SLIRLARPVKYEELY	MTMR7	96	Q9Y216
EPSDLIVKIYRAESY	LONRF1	241	Q17RB8
RSYRFPKLTVITEYL	IGF1R	71	P08069
FRYDLSPITVKYTER	ERGIC1	231	Q969X5
RYYKEIPLSEILTVE	PRKD2	436	Q9BZL6
KDPREIDPIVTRRYY	LAMA2	261	P24043
ERPYSTVRTKVYAIL	PELP1	421	Q8IZL8
YRLVSLRSTTPEELY	NBAS	516	A2RRP1
KNRYRDILPYDSTRV	PTPN20	186	Q4JDL3
YDYVKPRLRTTISRA	OGDH	966	Q02218
IKRYREYELVTPVST	ADAMTS3	36	O15072
NTVYVDRDILPKTLY	IFT80	536	Q9P2H3
RKKPVVYTRVSAYID	CTRC	246	Q99895
TVKKPLDYESRRLYT	CDH10	331	Q9Y6N8
YVEPITEERAARTLY	CHD6	1526	Q8TD26
REYLARTPEDRKVYT	CUL3	751	Q13618
YVIKLSEPDYVRTLE	DNAH7	3011	Q8WXX0
LYTLIVRPDNTYEVK	CALR	171	P27797
SDIAQRYRISKYPTL	ERP44	96	Q9BS26
SSVDIYRTPLYDLRI	MEMO1	91	Q9Y316
EDKRLTRPAYSYIAL	FOXL3	26	A0A1W2PRP0
KRDTINPLYDETLRY	SYTL4	416	Q96C24
RKRRVYETYESPLPI	TSEN2	11	Q8NCE0
EYLSRYTKSRKEPDA	SVIL	131	O95425
DRRYAYTEEPRVKTV	RGS22	636	Q8NE09
LKPYIRESSEQESLY	GIN1	421	Q9NXP7
QPYVEALLSYTRIKR	NR1H2	396	P55055
SILDRYYTPTISRER	PSMB2	141	P49721
YYTPTISRERAVELL	PSMB2	146	P49721
AKRRRVSLVLPEYYE	SPDYE10	96	P0DUX0
AKRRRVSLVLPEYYE	SPDYE11	96	P0DTA3
AKRRRVSLVLPEYYE	SPDYE8	96	P0DUD1
YESPERYSRSVLLIT	TAP1	686	Q03518
IRYVERSYVSKPTLK	ACAT1	26	P24752
VEEETRRYRPTKNYL	BCAS2	36	O75934
GELEYDKVPYSSLRR	CIC	1451	Q96RK0
PTALVYYRKRTIQLE	CLHC1	106	Q8NHS4
PYAKTYEGRREILRE	CLCC1	411	Q96S66
KEYYLRIESTVPIIC	VWDE	306	Q8N2E2
DYVRYTKLPRRVAEA	WASHC5	1131	Q12768
AIDVVPVDSKRYRYV	TBX22	141	Q9Y458
AKRRRVSLVLPEYYE	SPDYE12	96	P0DUX1
AKRRRVSLVLPEYYE	SPDYE13	96	A0A494C0Z2
AKRRRVSLVLPEYYE	SPDYE14	96	P0DUD3
AKRRRVSLVLPEYYE	SPDYE15	96	P0DUD4
AKRRRVSLVLPEYYE	SPDYE17	96	P0DUD2
AKRRRVSLVLPEYYE	SPDYE3	161	A6NKU9
KRRRVSLVLPEYYEA	SPDYE3	381	A6NKU9
PRTIYENRIYSLKIE	UBE2V1	56	Q13404
ERLRYKYPSVACEIL	PPP6R1	71	Q9UPN7
LRPRYTYFKVPTERD	WNT3A	256	P56704
LLEAIYPSVDKREYI	ZNF800	116	Q2TB10
AKRRRVSLVLPEYYE	SPDYE9	96	A0A494C191
ADPRYELPSRKYIST	ZBED1	156	O96006
REDTRIKPIYNLYAI	USP32	1501	Q8NFA0
QYPILLKDYRSTVVD	ULK4	916	Q96C45
LQLERRLIYTSDPKY	VPS13D	856	Q5THJ4