Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH10 DYNC2H1 DNAH7 DYNC1H1	2.66e-07	18	63	4	GO:0008569
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH10 DYNC2H1 DNAH7 DYNC1H1	1.74e-06	28	63	4	GO:0051959
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH10 DYNC2H1 DNAH7 DYNC1H1	5.49e-06	37	63	4	GO:0045505
GeneOntologyMolecularFunction	histone H3T6 kinase activity	PRKCA PRKCB	9.80e-06	2	63	2	GO:0035403
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF10 SP2 ZNF134 ZNF141 ZSCAN12 ZNF337 ZNF875 ZNF316 SP6 ZNF619 ZNF232 ZNF319 ZNF850 SP7 ZNF445	2.47e-05	1412	63	15	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF10 SP2 ZNF134 ZNF141 ZSCAN12 ZNF337 ZNF875 ZNF316 SP6 ZNF619 ZNF232 ZNF319 ZNF850 SP7 ZNF445	3.62e-05	1459	63	15	GO:0000977
GeneOntologyMolecularFunction	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	BIRC2 BIRC3 BIRC5	5.78e-05	24	63	3	GO:0043027
GeneOntologyMolecularFunction	microtubule motor activity	DNAH10 DYNC2H1 DNAH7 DYNC1H1	7.06e-05	70	63	4	GO:0003777
GeneOntologyMolecularFunction	clathrin light chain binding	CLTCL1 CLTC	2.04e-04	7	63	2	GO:0032051
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNAH10 DYNC2H1 DNAH7 DYNC1H1	5.27e-04	118	63	4	GO:0003774
GeneOntologyMolecularFunction	semaphorin receptor activity	MET PLXNA2	6.34e-04	12	63	2	GO:0017154
GeneOntologyMolecularFunction	histone H3 kinase activity	PRKCA PRKCB	6.34e-04	12	63	2	GO:0140996
GeneOntologyMolecularFunction	cysteine-type endopeptidase regulator activity involved in apoptotic process	BIRC2 BIRC3 BIRC5	6.62e-04	54	63	3	GO:0043028
GeneOntologyMolecularFunction	diacylglycerol-dependent serine/threonine kinase activity	PRKCA PRKCB	1.14e-03	16	63	2	GO:0004697
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SP2 ZNF134 ZNF141 ZSCAN12 ZNF316 SP6 ZNF232 ZNF319 ZNF850 SP7 ZNF445	1.62e-03	1244	63	11	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	SP2 ZNF134 ZNF141 ZSCAN12 ZNF316 SP6 ZNF232 ZNF319 ZNF850 SP7 ZNF445	1.92e-03	1271	63	11	GO:0000987
GeneOntologyMolecularFunction	histone kinase activity	PRKCA PRKCB	3.51e-03	28	63	2	GO:0035173
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	FBXO6 BIRC2 BIRC3 BIRC5 TNFAIP1 LONRF3	3.72e-03	473	63	6	GO:0004842
GeneOntologyBiologicalProcess	odontogenesis	JAG2 WNT7B SP6 RSPO2 PRKCB SP7	6.11e-06	151	62	6	GO:0042476
GeneOntologyBiologicalProcess	appendage morphogenesis	PCSK5 FRAS1 ZNF141 DYNC2H1 RSPO2 PLXNA2	1.95e-05	185	62	6	GO:0035107
GeneOntologyBiologicalProcess	limb morphogenesis	PCSK5 FRAS1 ZNF141 DYNC2H1 RSPO2 PLXNA2	1.95e-05	185	62	6	GO:0035108
GeneOntologyBiologicalProcess	regulation of odontogenesis	SP6 RSPO2 PRKCB	5.00e-05	24	62	3	GO:0042481
GeneOntologyBiologicalProcess	trachea cartilage morphogenesis	WNT7B RSPO2	5.31e-05	4	62	2	GO:0060535
GeneOntologyBiologicalProcess	limb development	PCSK5 FRAS1 ZNF141 DYNC2H1 RSPO2 PLXNA2	5.68e-05	224	62	6	GO:0060173
GeneOntologyBiologicalProcess	appendage development	PCSK5 FRAS1 ZNF141 DYNC2H1 RSPO2 PLXNA2	5.68e-05	224	62	6	GO:0048736
GeneOntologyBiologicalProcess	trachea cartilage development	WNT7B RSPO2	2.46e-04	8	62	2	GO:0060534
GeneOntologyBiologicalProcess	mitotic nuclear membrane disassembly	PRKCA PRKCB	2.46e-04	8	62	2	GO:0007077
GeneOntologyCellularComponent	dynein complex	DNAH10 DYNC2H1 DNAH7 DYNC1H1	1.99e-05	54	62	4	GO:0030286
GeneOntologyCellularComponent	microtubule associated complex	DNAH10 DYNC2H1 BIRC5 DNAH7 DYNC1H1	1.16e-04	161	62	5	GO:0005875
GeneOntologyCellularComponent	clathrin complex	CLTCL1 CLTC	3.07e-04	9	62	2	GO:0071439
GeneOntologyCellularComponent	inner dynein arm	DNAH10 DNAH7	3.84e-04	10	62	2	GO:0036156
MousePheno	absent kidney	PCSK5 FRAS1 DYNC2H1 RSPO2 AXIN1 NPNT	7.72e-09	53	40	6	MP:0000520
MousePheno	syndactyly	JAG2 PCSK5 FRAS1 DYNC2H1 SP6 RSPO2	2.36e-07	93	40	6	MP:0000564
MousePheno	abnormal lung vasculature morphology	FRAS1 DYNC2H1 WNT7B RSPO2	7.04e-05	78	40	4	MP:0004007
Domain	ZINC_FINGER_C2H2_2	ZNF10 SP2 ZNF134 ZNF141 ZNF337 ZNF875 ZNF316 HELZ2 SP6 ZNF619 ZNF232 ZNF319 ZNF850 SP7 ZNF445	1.51e-08	775	60	15	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF10 SP2 ZNF134 ZNF141 ZNF337 ZNF875 ZNF316 HELZ2 SP6 ZNF619 ZNF232 ZNF319 ZNF850 SP7 ZNF445	1.57e-08	777	60	15	PS00028
Domain	Znf_C2H2-like	ZNF10 SP2 ZNF134 ZNF141 ZNF337 ZNF875 ZNF316 HELZ2 SP6 ZNF619 ZNF232 ZNF319 ZNF850 SP7 ZNF445	2.16e-08	796	60	15	IPR015880
Domain	-	ZNF10 SP2 ZNF134 ZNF141 ZNF337 ZNF875 ZNF316 SP6 ZNF619 ZNF232 ZNF319 ZNF850 SP7 ZNF445	2.27e-08	679	60	14	3.30.160.60
Domain	ZnF_C2H2	ZNF10 SP2 ZNF134 ZNF141 ZNF337 ZNF875 ZNF316 HELZ2 SP6 ZNF619 ZNF232 ZNF319 ZNF850 SP7 ZNF445	2.64e-08	808	60	15	SM00355
Domain	zf-C2H2	ZNF10 SP2 ZNF134 ZNF141 ZNF337 ZNF875 ZNF316 SP6 ZNF619 ZNF232 ZNF319 ZNF850 SP7 ZNF445	2.93e-08	693	60	14	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF10 SP2 ZNF134 ZNF141 ZNF337 ZNF875 ZNF316 SP6 ZNF619 ZNF232 ZNF319 ZNF850 SP7 ZNF445	2.99e-08	694	60	14	IPR013087
Domain	Dynein_heavy_chain_D4_dom	DNAH10 DYNC2H1 DNAH7 DYNC1H1	9.40e-08	14	60	4	IPR024317
Domain	Dynein_HC_stalk	DNAH10 DYNC2H1 DNAH7 DYNC1H1	9.40e-08	14	60	4	IPR024743
Domain	Dynein_heavy_dom-2	DNAH10 DYNC2H1 DNAH7 DYNC1H1	9.40e-08	14	60	4	IPR013602
Domain	DHC_N2	DNAH10 DYNC2H1 DNAH7 DYNC1H1	9.40e-08	14	60	4	PF08393
Domain	MT	DNAH10 DYNC2H1 DNAH7 DYNC1H1	9.40e-08	14	60	4	PF12777
Domain	AAA_8	DNAH10 DYNC2H1 DNAH7 DYNC1H1	9.40e-08	14	60	4	PF12780
Domain	DHC_fam	DNAH10 DYNC2H1 DNAH7 DYNC1H1	1.28e-07	15	60	4	IPR026983
Domain	Dynein_heavy_dom	DNAH10 DYNC2H1 DNAH7 DYNC1H1	1.28e-07	15	60	4	IPR004273
Domain	Dynein_heavy	DNAH10 DYNC2H1 DNAH7 DYNC1H1	1.28e-07	15	60	4	PF03028
Domain	Znf_C2H2	ZNF10 SP2 ZNF134 ZNF141 ZNF337 ZNF875 ZNF316 SP6 ZNF619 ZNF232 ZNF319 ZNF850 SP7 ZNF445	1.87e-07	805	60	14	IPR007087
Domain	BIR	BIRC2 BIRC3 BIRC5	1.74e-06	8	60	3	SM00238
Domain	-	BIRC2 BIRC3 BIRC5	1.74e-06	8	60	3	1.10.1170.10
Domain	BIR	BIRC2 BIRC3 BIRC5	1.74e-06	8	60	3	PF00653
Domain	DHC_N1	DNAH10 DYNC2H1 DYNC1H1	1.74e-06	8	60	3	PF08385
Domain	BIR_REPEAT_2	BIRC2 BIRC3 BIRC5	1.74e-06	8	60	3	PS50143
Domain	BIR_rpt	BIRC2 BIRC3 BIRC5	1.74e-06	8	60	3	IPR001370
Domain	Dynein_heavy_dom-1	DNAH10 DYNC2H1 DYNC1H1	1.74e-06	8	60	3	IPR013594
Domain	BIR_REPEAT_1	BIRC2 BIRC3 BIRC5	1.74e-06	8	60	3	PS01282
Domain	Sp1_fam	SP2 SP6 SP7	3.72e-06	10	60	3	IPR030450
Domain	Clathrin_H-chain_propeller_rpt	CLTCL1 CLTC	1.01e-05	2	60	2	IPR022365
Domain	Clathrin-link	CLTCL1 CLTC	1.01e-05	2	60	2	PF09268
Domain	-	CLTCL1 CLTC	1.01e-05	2	60	2	2.130.10.110
Domain	Clathrin_H-chain_link/propller	CLTCL1 CLTC	1.01e-05	2	60	2	IPR016025
Domain	Clathrin_propel	CLTCL1 CLTC	1.01e-05	2	60	2	PF01394
Domain	Clathrin_heavy_chain	CLTCL1 CLTC	1.01e-05	2	60	2	IPR016341
Domain	Clathrin_H-chain_linker_core	CLTCL1 CLTC	1.01e-05	2	60	2	IPR015348
Domain	Clathrin_H-chain_propeller_N	CLTCL1 CLTC	1.01e-05	2	60	2	IPR001473
Domain	ATPase_dyneun-rel_AAA	DNAH10 DYNC2H1 DYNC1H1	1.12e-05	14	60	3	IPR011704
Domain	AAA_5	DNAH10 DYNC2H1 DYNC1H1	1.12e-05	14	60	3	PF07728
Domain	Furin_repeat	PCSK5 FRAS1 RSPO2	2.49e-05	18	60	3	IPR006212
Domain	FU	PCSK5 FRAS1 RSPO2	2.49e-05	18	60	3	SM00261
Domain	Clathrin_H-chain_linker	CLTCL1 CLTC	3.04e-05	3	60	2	IPR012331
Domain	Protein_kinase_C_a/b/g	PRKCA PRKCB	3.04e-05	3	60	2	IPR014375
Domain	CLH	CLTCL1 CLTC	3.04e-05	3	60	2	SM00299
Domain	DAG/PE-bd	RASGRP1 PRKCA PRKCB	4.02e-05	21	60	3	IPR020454
Domain	IPT	MET PKHD1L1 PLXNA2	8.73e-05	27	60	3	SM00429
Domain	AAA+_ATPase	DNAH10 DYNC2H1 HELZ2 DNAH7 DYNC1H1	9.87e-05	144	60	5	IPR003593
Domain	AAA	DNAH10 DYNC2H1 HELZ2 DNAH7 DYNC1H1	9.87e-05	144	60	5	SM00382
Domain	EGF	JAG2 PCSK5 FRAS1 NRXN2 BCAN NPNT	1.06e-04	235	60	6	SM00181
Domain	TIG	MET PKHD1L1 PLXNA2	1.33e-04	31	60	3	PF01833
Domain	Growth_fac_rcpt_	JAG2 PCSK5 FRAS1 RSPO2 NPNT	1.44e-04	156	60	5	IPR009030
Domain	KRAB	ZNF10 ZNF141 ZNF337 ZNF875 ZNF316 ZNF850 ZNF445	1.45e-04	358	60	7	PS50805
Domain	KRAB	ZNF10 ZNF141 ZNF337 ZNF875 ZNF316 ZNF850 ZNF445	1.45e-04	358	60	7	PF01352
Domain	EGF-like_dom	JAG2 PCSK5 FRAS1 NRXN2 BCAN NPNT	1.45e-04	249	60	6	IPR000742
Domain	IPT	MET PKHD1L1 PLXNA2	1.46e-04	32	60	3	IPR002909
Domain	KRAB	ZNF10 ZNF141 ZNF337 ZNF875 ZNF316 ZNF850 ZNF445	1.74e-04	369	60	7	SM00349
Domain	KRAB	ZNF10 ZNF141 ZNF337 ZNF875 ZNF316 ZNF850 ZNF445	1.77e-04	370	60	7	IPR001909
Domain	Clathrin	CLTCL1 CLTC	2.11e-04	7	60	2	PF00637
Domain	CHCR	CLTCL1 CLTC	2.11e-04	7	60	2	PS50236
Domain	Clathrin_H-chain/VPS_repeat	CLTCL1 CLTC	2.81e-04	8	60	2	IPR000547
Domain	zf-C2H2_6	ZNF10 ZNF141 ZNF316 ZNF619 ZNF850 ZNF445	5.03e-04	314	60	6	PF13912
Domain	C1_1	RASGRP1 PRKCA PRKCB	8.15e-04	57	60	3	PF00130
Domain	ZF_DAG_PE_1	RASGRP1 PRKCA PRKCB	1.14e-03	64	60	3	PS00479
Domain	ZF_DAG_PE_2	RASGRP1 PRKCA PRKCB	1.14e-03	64	60	3	PS50081
Domain	CARD	BIRC2 BIRC3	1.18e-03	16	60	2	SM00114
Domain	C1	RASGRP1 PRKCA PRKCB	1.19e-03	65	60	3	SM00109
Domain	PE/DAG-bd	RASGRP1 PRKCA PRKCB	1.25e-03	66	60	3	IPR002219
Domain	VWC_out	JAG2 FRAS1	1.68e-03	19	60	2	SM00215
Domain	Galactose-bd-like	PCSK5 FBXO6 NGLY1	3.43e-03	94	60	3	IPR008979
Domain	CARD	BIRC2 BIRC3	3.64e-03	28	60	2	PF00619
Domain	CARD	BIRC2 BIRC3	4.44e-03	31	60	2	IPR001315
Domain	Sema	MET PLXNA2	4.44e-03	31	60	2	SM00630
Domain	Semap_dom	MET PLXNA2	4.44e-03	31	60	2	IPR001627
Domain	Sema	MET PLXNA2	4.44e-03	31	60	2	PF01403
Domain	SEMA	MET PLXNA2	4.44e-03	31	60	2	PS51004
Domain	Ig_E-set	MET PKHD1L1 PLXNA2	4.56e-03	104	60	3	IPR014756
Domain	PSI	MET PLXNA2	4.73e-03	32	60	2	PF01437
Domain	Plexin_repeat	MET PLXNA2	4.73e-03	32	60	2	IPR002165
Domain	CARD	BIRC2 BIRC3	5.03e-03	33	60	2	PS50209
Domain	VWFC_1	JAG2 FRAS1	5.96e-03	36	60	2	PS01208
Domain	Pkinase_C	PRKCA PRKCB	6.29e-03	37	60	2	IPR017892
Pathway	WP_CANCER_PATHWAYS	JAG2 MET RASGRP1 WNT7B BIRC2 PRKCA BIRC3 PRKCB BIRC5 AXIN1	4.21e-06	507	46	10	M48302
Pathway	BIOCARTA_CBL_PATHWAY	MET PRKCA PRKCB	5.27e-06	11	46	3	MM1360
Pathway	BIOCARTA_CBL_PATHWAY	MET PRKCA PRKCB	7.01e-06	12	46	3	M16973
Pathway	KEGG_PATHWAYS_IN_CANCER	MET WNT7B BIRC2 PRKCA BIRC3 PRKCB BIRC5 AXIN1	8.90e-06	325	46	8	M12868
Pathway	REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD4	CLTC PRKCA PRKCB	1.44e-05	15	46	3	M27413
Pathway	WP_WNT_SIGNALING	WNT7B PRKCA PRKCB AXIN1	4.52e-05	61	46	4	MM15893
Pathway	WP_INTRAFLAGELLAR_TRANSPORT_PROTEINS_BINDING_TO_DYNEIN	IFT22 DYNC2H1 DYNC1H1	9.00e-05	27	46	3	M39827
Pathway	BIOCARTA_ION_PATHWAY	PRKCA PRKCB	1.04e-04	5	46	2	MM1574
Pathway	BIOCARTA_PLCD_PATHWAY	PRKCA PRKCB	1.04e-04	5	46	2	MM1587
Pathway	BIOCARTA_ION_PATHWAY	PRKCA PRKCB	1.04e-04	5	46	2	M22059
Pathway	BIOCARTA_PLCD_PATHWAY	PRKCA PRKCB	1.04e-04	5	46	2	M22080
Pathway	REACTOME_DISINHIBITION_OF_SNARE_FORMATION	PRKCA PRKCB	1.04e-04	5	46	2	M26920
Pathway	PID_RAS_PATHWAY	RASGRP1 PRKCA PRKCB	1.24e-04	30	46	3	M269
Pathway	WP_PHOTODYNAMIC_THERAPYINDUCED_NFKB_SURVIVAL_SIGNALING	BIRC2 BIRC3 BIRC5	1.98e-04	35	46	3	M39529
Pathway	BIOCARTA_ERBB4_PATHWAY	PRKCA PRKCB	2.16e-04	7	46	2	MM1563
Pathway	BIOCARTA_PKC_PATHWAY	PRKCA PRKCB	2.16e-04	7	46	2	MM1572
Pathway	BIOCARTA_ERBB4_PATHWAY	PRKCA PRKCB	2.16e-04	7	46	2	M22043
Pathway	BIOCARTA_PKC_PATHWAY	PRKCA PRKCB	2.16e-04	7	46	2	M22057
Pathway	PID_FAS_PATHWAY	CLTC BIRC2 BIRC3	2.53e-04	38	46	3	M94
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_US27_TO_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY	PRKCA PRKCB	2.88e-04	8	46	2	M47555
Pathway	KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PLCG_PKC_SIGNALING_PATHWAY	PRKCA PRKCB	2.88e-04	8	46	2	M47479
Pathway	WP_WNT_SIGNALING_AND_PLURIPOTENCY	WNT7B PRKCA PRKCB AXIN1	3.22e-04	101	46	4	M39387
Pathway	WP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY	WNT7B PRKCA PRKCB AXIN1	3.22e-04	101	46	4	MM15829
Pathway	BIOCARTA_PLC_PATHWAY	PRKCA PRKCB	3.70e-04	9	46	2	M22029
Pathway	BIOCARTA_PLC_PATHWAY	PRKCA PRKCB	3.70e-04	9	46	2	MM1551
Pathway	WP_FOCAL_ADHESION	MET BIRC2 PRKCA BIRC3 PRKCB	4.57e-04	199	46	5	M39402
Pathway	KEGG_FOCAL_ADHESION	MET BIRC2 PRKCA BIRC3 PRKCB	4.57e-04	199	46	5	M7253
Pathway	BIOCARTA_SRCRPTP_PATHWAY	PRKCA PRKCB	4.61e-04	10	46	2	MM1341
Pathway	BIOCARTA_AGPCR_PATHWAY	PRKCA PRKCB	4.61e-04	10	46	2	MM1352
Pathway	KEGG_MEDICUS_REFERENCE_TAC3_TACR3_PLC_PKC_SIGNALING_PATHWAY	PRKCA PRKCB	4.61e-04	10	46	2	M47644
Pathway	WP_WNT_SIGNALING_WP428	WNT7B PRKCA PRKCB AXIN1	4.93e-04	113	46	4	M39669
Pathway	WP_GASTRIN_SIGNALING	BIRC2 PRKCA BIRC3 BIRC5	5.27e-04	115	46	4	M39866
Pathway	KEGG_MEDICUS_REFERENCE_KISS1_KISS1R_PLCB_PKC_SIGNALING_PATHWAY	PRKCA PRKCB	5.62e-04	11	46	2	M47637
Pathway	BIOCARTA_SRCRPTP_PATHWAY	PRKCA PRKCB	5.62e-04	11	46	2	M10994
Pathway	BIOCARTA_MYOSIN_PATHWAY	PRKCA PRKCB	5.62e-04	11	46	2	M7014
Pathway	BIOCARTA_AGPCR_PATHWAY	PRKCA PRKCB	5.62e-04	11	46	2	M19829
Pathway	WP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES	JAG2 WNT7B PRKCA PRKCB	5.80e-04	118	46	4	M39852
Pathway	WP_WNT_SIGNALING_WP363	PRKCA PRKCB AXIN1	6.07e-04	51	46	3	M39721
Pathway	REACTOME_SIGNALING_BY_WNT	WNT7B CLTC RSPO2 PRKCA PRKCB AXIN1	6.69e-04	330	46	6	M7847
Pathway	KEGG_MEDICUS_PATHOGEN_HBV_LHBS_TO_PKC_ERK_SIGNALING_PATHWAY	PRKCA PRKCB	6.73e-04	12	46	2	M47597
Pathway	KEGG_MEDICUS_REFERENCE_TRH_TRHR_PLCB_PKC_SIGNALING_PATHWAY	PRKCA PRKCB	6.73e-04	12	46	2	M47649
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_APC_TO_WNT_SIGNALING_PATHWAY	BIRC5 AXIN1	6.73e-04	12	46	2	M47410
Pathway	KEGG_MEDICUS_PATHOGEN_HSV_GD_TO_HVEM_NFKB_SIGNALING_PATHWAY	BIRC2 BIRC3	6.73e-04	12	46	2	M47600
Pathway	KEGG_MEDICUS_REFERENCE_TSH_DUOX2_TG_SIGNALING_PATHWAY	PRKCA PRKCB	6.73e-04	12	46	2	M47628
Pathway	REACTOME_GAP_JUNCTION_DEGRADATION	CLTCL1 CLTC	6.73e-04	12	46	2	M15243
Pathway	PID_CD8_TCR_PATHWAY	RASGRP1 PRKCA PRKCB	6.80e-04	53	46	3	M88
Pathway	KEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY	PRKCA PRKCB	7.94e-04	13	46	2	M47656
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PLCG_ERK_SIGNALING_PATHWAY	PRKCA PRKCB	9.25e-04	14	46	2	M47383
Pathway	KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PLCG_ERK_SIGNALING_PATHWAY	PRKCA PRKCB	9.25e-04	14	46	2	M47384
Pathway	PID_TCR_RAS_PATHWAY	PRKCA PRKCB	9.25e-04	14	46	2	M134
Pathway	REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD4	CLTC PRKCB	9.25e-04	14	46	2	MM15161
Pathway	BIOCARTA_TRKA_PATHWAY	PRKCA PRKCB	9.25e-04	14	46	2	M9134
Pathway	REACTOME_SIGNALING_BY_WNT	WNT7B CLTC RSPO2 PRKCB AXIN1	1.04e-03	239	46	5	MM14756
Pathway	BIOCARTA_CDMAC_PATHWAY	PRKCA PRKCB	1.06e-03	15	46	2	MM1358
Pathway	BIOCARTA_TRKA_PATHWAY	PRKCA PRKCB	1.06e-03	15	46	2	MM1523
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_ERK_SIGNALING_PATHWAY	PRKCA PRKCB	1.06e-03	15	46	2	M47382
Pathway	REACTOME_DEPOLYMERIZATION_OF_THE_NUCLEAR_LAMINA	PRKCA PRKCB	1.06e-03	15	46	2	M27360
Pathway	PID_TCR_PATHWAY	RASGRP1 PRKCA PRKCB	1.18e-03	64	46	3	M34
Pathway	BIOCARTA_MEF2D_PATHWAY	PRKCA PRKCB	1.21e-03	16	46	2	MM1483
Pathway	BIOCARTA_SPPA_PATHWAY	PRKCA PRKCB	1.21e-03	16	46	2	M8731
Pathway	BIOCARTA_CDMAC_PATHWAY	PRKCA PRKCB	1.21e-03	16	46	2	M4388
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF10 MET ZNF141 ZNF337 ZNF875 PRKCB BIRC5 ZNF619 TOP3A AXIN1 SP7 ZNF445	1.28e-03	1387	46	12	M734
Pathway	REACTOME_TNF_RECEPTOR_SUPERFAMILY_TNFSF_MEMBERS_MEDIATING_NON_CANONICAL_NF_KB_PATHWAY	BIRC2 BIRC3	1.37e-03	17	46	2	M27561
Pathway	BIOCARTA_CCR5_PATHWAY	PRKCA PRKCB	1.37e-03	17	46	2	M2349
Pathway	REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS	PRKCA PRKCB	1.37e-03	17	46	2	M5488
Pathway	KEGG_WNT_SIGNALING_PATHWAY	WNT7B PRKCA PRKCB AXIN1	1.46e-03	151	46	4	M19428
Pathway	BIOCARTA_CHEMICAL_PATHWAY	PRKCA PRKCB	1.54e-03	18	46	2	MM1350
Pathway	REACTOME_TNF_RECEPTOR_SUPERFAMILY_TNFSF_MEMBERS_MEDIATING_NON_CANONICAL_NF_KB_PATHWAY	BIRC2 BIRC3	1.54e-03	18	46	2	MM15275
Pathway	BIOCARTA_CARDIACEGF_PATHWAY	PRKCA PRKCB	1.54e-03	18	46	2	M7552
Pathway	BIOCARTA_MEF2D_PATHWAY	PRKCA PRKCB	1.54e-03	18	46	2	M5290
Pathway	BIOCARTA_CALCINEURIN_PATHWAY	PRKCA PRKCB	1.54e-03	18	46	2	MM1385
Pathway	BIOCARTA_CALCINEURIN_PATHWAY	PRKCA PRKCB	1.54e-03	18	46	2	M3430
Pathway	BIOCARTA_CARDIACEGF_PATHWAY	PRKCA PRKCB	1.54e-03	18	46	2	MM1479
Pathway	BIOCARTA_CHEMICAL_PATHWAY	PRKCA PRKCB	1.54e-03	18	46	2	M3873
Pathway	WP_KIT_RECEPTOR_SIGNALING_PATHWAY	CLTC PRKCA PRKCB	1.59e-03	71	46	3	MM15947
Pathway	BIOCARTA_CCR3_PATHWAY	PRKCA PRKCB	1.72e-03	19	46	2	MM1361
Pathway	KEGG_MEDICUS_REFERENCE_CXCL12_CXCR4_PKC_ERK_SIGNALING_PATHAWAY	PRKCA PRKCB	1.72e-03	19	46	2	M47596
Pathway	BIOCARTA_PAR1_PATHWAY	PRKCA PRKCB	1.72e-03	19	46	2	MM1514
Pathway	BIOCARTA_MITOCHONDRIA_PATHWAY	BIRC2 BIRC3	1.72e-03	19	46	2	M16257
Pathway	BIOCARTA_CXCR4_PATHWAY	PRKCA PRKCB	1.72e-03	19	46	2	MM1375
Pathway	BIOCARTA_CXCR4_PATHWAY	PRKCA PRKCB	1.72e-03	19	46	2	M882
Pathway	BIOCARTA_CCR5_PATHWAY	PRKCA PRKCB	1.72e-03	19	46	2	MM1453
Pathway	REACTOME_VEGFR2_MEDIATED_CELL_PROLIFERATION	PRKCA PRKCB	1.72e-03	19	46	2	M27423
Pathway	BIOCARTA_PAR1_PATHWAY	PRKCA PRKCB	1.72e-03	19	46	2	M3494
Pathway	REACTOME_TICAM1_RIP1_MEDIATED_IKK_COMPLEX_RECRUITMENT	BIRC2 BIRC3	1.72e-03	19	46	2	M27020
Pathway	SA_CASPASE_CASCADE	BIRC2 BIRC3	1.72e-03	19	46	2	M7997
Pathway	BIOCARTA_CCR3_PATHWAY	PRKCA PRKCB	1.72e-03	19	46	2	M9152
Pathway	WP_SMITHMAGENIS_AND_POTOCKILUPSKI_SYNDROME_COPY_NUMBER_VARIATION	IFT22 CLTC BIRC2 TOP3A	1.76e-03	159	46	4	M48090
Pathway	BIOCARTA_CREB_PATHWAY	PRKCA PRKCB	1.91e-03	20	46	2	MM1520
Pathway	BIOCARTA_NOS1_PATHWAY	PRKCA PRKCB	1.91e-03	20	46	2	MM1445
Pathway	BIOCARTA_EDG1_PATHWAY	PRKCA PRKCB	1.91e-03	20	46	2	MM1456
Pathway	BIOCARTA_ARENRF2_PATHWAY	PRKCA PRKCB	1.91e-03	20	46	2	M14339
Pathway	KEGG_MEDICUS_REFERENCE_GNRH_GNRHR_PLCB_PKC_SIGNALING_PATHWAY	PRKCA PRKCB	2.10e-03	21	46	2	M47638
Pathway	BIOCARTA_NOS1_PATHWAY	PRKCA PRKCB	2.10e-03	21	46	2	M11650
Pathway	BIOCARTA_MITOCHONDRIA_PATHWAY	BIRC2 BIRC3	2.10e-03	21	46	2	MM1484
Pathway	BIOCARTA_EDG1_PATHWAY	PRKCA PRKCB	2.31e-03	22	46	2	M10579
Pathway	BIOCARTA_CREB_PATHWAY	PRKCA PRKCB	2.31e-03	22	46	2	M9070
Pathway	BIOCARTA_ARENRF2_PATHWAY	PRKCA PRKCB	2.31e-03	22	46	2	MM1449
Pathway	BIOCARTA_CASPASE_PATHWAY	BIRC2 BIRC3	2.31e-03	22	46	2	M17902
Pathway	WP_APOPTOSIS	BIRC2 BIRC3 BIRC5	2.49e-03	83	46	3	MM15972
Pubmed	Increased Expression of BIRC2, BIRC3, and BIRC5 from the IAP Family in Mesenchymal Stem Cells of the Umbilical Cord Wharton's Jelly (WJSC) in Younger Women Giving Birth Naturally.	BIRC2 BIRC3 BIRC5	5.94e-09	3	64	3	32322338
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH10 DYNC2H1 DNAH7 DYNC1H1	1.03e-08	14	64	4	9373155
Pubmed	cIAP1 Localizes to the nuclear compartment and modulates the cell cycle.	BIRC2 BIRC3 BIRC5	2.37e-08	4	64	3	15665297
Pubmed	Cartilage oligomeric matrix protein protects cells against death by elevating members of the IAP family of survival proteins.	BIRC2 BIRC3 BIRC5	5.93e-08	5	64	3	17993464
Pubmed	Survivin acts as an antiapoptotic factor during the development of mouse preimplantation embryos.	BIRC2 BIRC3 BIRC5	5.93e-08	5	64	3	12679106
Pubmed	An IAP-IAP complex inhibits apoptosis.	BIRC2 BIRC3 BIRC5	1.18e-07	6	64	3	15218035
Pubmed	Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex.	BIRC2 BIRC3 BIRC5	2.07e-07	7	64	3	17613533
Pubmed	The inhibitors of apoptosis (IAPs) and their emerging role in cancer.	BIRC2 BIRC3 BIRC5	2.07e-07	7	64	3	9916987
Pubmed	The inhibitors of apoptosis: there is more to life than Bcl2.	BIRC2 BIRC3 BIRC5	2.07e-07	7	64	3	14634619
Pubmed	Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.	MET CLTC BIRC2 PRKCA BIRC3 PRKCB BIRC5 AXIN1	4.09e-07	371	64	8	25241761
Pubmed	Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression.	BIRC2 BIRC3 BIRC5	7.07e-07	10	64	3	23384561
Pubmed	Distinct and complementary roles for α and β isoenzymes of PKC in mediating vasoconstrictor responses to acutely elevated glucose.	PRKCA PRKCB	3.33e-06	2	64	2	26660275
Pubmed	Characterization of a second human clathrin heavy chain polypeptide gene (CLH-22) from chromosome 22q11.	CLTCL1 CLTC	3.33e-06	2	64	2	8733129
Pubmed	Insulin inhibits phagocytosis in normal human neutrophils via PKCalpha/beta-dependent priming of F-actin assembly.	PRKCA PRKCB	3.33e-06	2	64	2	16673150
Pubmed	Heterogeneity of cellular proliferation within transitional cell carcinoma: correlation of protein kinase C alpha/betaI expression and activity.	PRKCA PRKCB	3.33e-06	2	64	2	16517978
Pubmed	Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are increased after labour in foetal membranes and myometrium and are essential for TNF-α-induced expression of pro-labour mediators.	BIRC2 BIRC3	3.33e-06	2	64	2	25046208
Pubmed	Effects of azidothymidine on protein kinase C activity and expression in erythroleukemic cell K562 and acute lymphoblastic leukemia cell HSB-2.	PRKCA PRKCB	3.33e-06	2	64	2	25693686
Pubmed	Baculoviral inhibitors of apoptosis repeat containing (BIRC) proteins fine-tune TNF-induced nuclear factor κB and c-Jun N-terminal kinase signalling in mouse pancreatic beta cells.	BIRC2 BIRC3	3.33e-06	2	64	2	23250032
Pubmed	Cellular inhibitor of apoptosis protein 1 (cIAP1) stability contributes to YM155 resistance in human gastric cancer cells.	BIRC2 BIRC5	3.33e-06	2	64	2	25635055
Pubmed	[Slow retinal degeneration in a mouse model: morphological and functional aspects].	PRPH2 RPE65	3.33e-06	2	64	2	27116862
Pubmed	Calcium-dependent isoforms of protein kinase C mediate posttetanic potentiation at the calyx of Held.	PRKCA PRKCB	3.33e-06	2	64	2	21658591
Pubmed	CXCL17 induces activation of human mast cells via MRGPRX2.	CXCL17 MRGPRX2	3.33e-06	2	64	2	38279626
Pubmed	Self-termination of the terminator.	BIRC2 BIRC3	3.33e-06	2	64	2	19008929
Pubmed	Cellular inhibitors of apoptosis are global regulators of NF-κB and MAPK activation by members of the TNF family of receptors.	BIRC2 BIRC3	3.33e-06	2	64	2	22434933
Pubmed	Reactivation of fetal splicing programs in diabetic hearts is mediated by protein kinase C signaling.	PRKCA PRKCB	3.33e-06	2	64	2	24151077
Pubmed	CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.	CLTCL1 CLTC	3.33e-06	2	64	2	29097553
Pubmed	Nuclear cIAP1 overexpression is a tumor stage- and grade-independent predictor of poor prognosis in human bladder cancer patients.	BIRC2 BIRC3	3.33e-06	2	64	2	21795072
Pubmed	Transient activation of PKC results in long-lasting detrimental effects on systolic [Ca2+]i in cardiomyocytes by altering actin cytoskeletal dynamics and T-tubule integrity.	PRKCA PRKCB	3.33e-06	2	64	2	29307535
Pubmed	BIRC2-BIRC3 amplification: a potentially druggable feature of a subset of head and neck cancers in patients with Fanconi anemia.	BIRC2 BIRC3	3.33e-06	2	64	2	34997070
Pubmed	Genes encoding catalytic subunits of protein kinase A and risk of spina bifida.	PRKCA PRKCB	3.33e-06	2	64	2	16080189
Pubmed	Receptor-specific regulation of atrial GIRK channel activity by different Ca2+-dependent PKC isoforms.	PRKCA PRKCB	3.33e-06	2	64	2	31525436
Pubmed	Structural basis of sugar recognition by SCFFBS2 ubiquitin ligase involved in NGLY1 deficiency.	FBXO6 NGLY1	3.33e-06	2	64	2	39171510
Pubmed	Prognostic Significance of the BIRC2-BIRC3 Gene Signature in Head and Neck Squamous Cell Carcinoma.	BIRC2 BIRC3	3.33e-06	2	64	2	35985688
Pubmed	Genomic organization and physical map of the human inhibitors of apoptosis: HIAP1 and HIAP2.	BIRC2 BIRC3	3.33e-06	2	64	2	9892732
Pubmed	Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2.	BIRC2 BIRC3	3.33e-06	2	64	2	29452637
Pubmed	Cellular inhibitors of apoptosis (cIAP) 1 and 2 are increased in placenta from obese pregnant women.	BIRC2 BIRC3	3.33e-06	2	64	2	25113061
Pubmed	Unravelling the different functions of protein kinase C isoforms in platelets.	PRKCA PRKCB	3.33e-06	2	64	2	21596041
Pubmed	Genomic characterization of the mouse inhibitor of apoptosis protein 1 and 2 genes.	BIRC2 BIRC3	3.33e-06	2	64	2	9441758
Pubmed	Inhibition of microtubules and dynein rescues human immunodeficiency virus type 1 from owl monkey TRIMCyp-mediated restriction in a cellular context-specific fashion.	DYNC2H1 DYNC1H1	3.33e-06	2	64	2	25502651
Pubmed	Genetic analysis of the cytoplasmic dynein subunit families.	DYNC2H1 DYNC1H1	3.33e-06	2	64	2	16440056
Pubmed	Generation of a poor prognostic chronic lymphocytic leukemia-like disease model: PKCα subversion induces up-regulation of PKCβII expression in B lymphocytes.	PRKCA PRKCB	3.33e-06	2	64	2	25616575
Pubmed	The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step.	CLTCL1 CLTC	3.33e-06	2	64	2	20065094
Pubmed	c-IAP1 and c-IAP2 redundancy differs between T and B cells.	BIRC2 BIRC3	3.33e-06	2	64	2	23799077
Pubmed	Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy.	BIRC2 BIRC3	3.33e-06	2	64	2	31126323
Pubmed	PKCα and PKCβ cooperate functionally in CD3-induced de novo IL-2 mRNA transcription.	PRKCA PRKCB	3.33e-06	2	64	2	23439007
Pubmed	cIAP-2 and survivin contribute to cytokine-mediated delayed eosinophil apoptosis.	BIRC3 BIRC5	3.33e-06	2	64	2	16761316
Pubmed	All-trans retinoic acid and protein kinase C α/β1 inhibitor combined treatment targets cancer stem cells and impairs breast tumor progression.	PRKCA PRKCB	3.33e-06	2	64	2	33723318
Pubmed	Adaptive regulation maintains posttetanic potentiation at cerebellar granule cell synapses in the absence of calcium-dependent PKC.	PRKCA PRKCB	3.33e-06	2	64	2	22993418
Pubmed	A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes.	BIRC2 BIRC3	3.33e-06	2	64	2	12651874
Pubmed	IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer.	BIRC2 BIRC3	3.33e-06	2	64	2	20651737
Pubmed	Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli.	BIRC2 BIRC3	3.33e-06	2	64	2	10797013
Pubmed	The essentiality of PKCalpha and PKCbetaI translocation for CD14+monocyte differentiation towards macrophages and dendritic cells, respectively.	PRKCA PRKCB	3.33e-06	2	64	2	17455194
Pubmed	Disease Phenotypes in a Mouse Model of RNA Toxicity Are Independent of Protein Kinase Cα and Protein Kinase Cβ.	PRKCA PRKCB	3.33e-06	2	64	2	27657532
Pubmed	Epithelial-mesenchymal transdifferentiation of renal tubular epithelial cells induced by urinary proteins requires the activation of PKC-α and βI isozymes.	PRKCA PRKCB	3.33e-06	2	64	2	21323641
Pubmed	Calcium-dependent isoforms of protein kinase C mediate glycine-induced synaptic enhancement at the calyx of Held.	PRKCA PRKCB	3.33e-06	2	64	2	23035091
Pubmed	Distinct functions of protein kinase Calpha and protein kinase Cbeta during retinoic acid-induced differentiation of F9 cells.	PRKCA PRKCB	3.33e-06	2	64	2	9486851
Pubmed	Subcellular expression of c-IAP1 and c-IAP2 in colorectal cancers: relationships with clinicopathological features and prognosis.	BIRC2 BIRC3	3.33e-06	2	64	2	14708638
Pubmed	Protein kinase C alpha, betaI, and betaII isozymes regulate cytokine production in mast cells through MEKK2/ERK5-dependent and -independent pathways.	PRKCA PRKCB	3.33e-06	2	64	2	16430878
Pubmed	Suppression of PKC causes oncogenic stress for triggering apoptosis in cancer cells.	PRKCA PRKCB	3.33e-06	2	64	2	28415683
Pubmed	Inhibition of the calcium release-activated calcium (CRAC) current in Jurkat T cells by the HIV-1 envelope protein gp160.	PRKCA PRKCB	3.33e-06	2	64	2	11744714
Pubmed	Functional evaluation of the role of inhibitor of apoptosis proteins in chronic lymphocytic leukemia.	BIRC2 BIRC3	3.33e-06	2	64	2	15183896
Pubmed	Role of IAPs in prostate cancer progression: immunohistochemical study in normal and pathological (benign hyperplastic, prostatic intraepithelial neoplasia and cancer) human prostate.	BIRC2 BIRC3	3.33e-06	2	64	2	20078866
Pubmed	cPKC-dependent sequestration of membrane-recycling components in a subset of recycling endosomes.	PRKCA PRKCB	3.33e-06	2	64	2	14527960
Pubmed	Degradation of cIAPs contributes to hepatocyte lipoapoptosis.	BIRC2 BIRC3	3.33e-06	2	64	2	24008361
Pubmed	Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression.	BIRC2 BIRC3 BIRC5	3.97e-06	17	64	3	20080598
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	JAG2 PCSK5 FRAS1 CLTCL1 ANKRD37 WNT7B ZNF316 HELZ2 ZFYVE26 DYNC1H1 TOP3A	5.04e-06	1105	64	11	35748872
Pubmed	Inhibitor of apoptosis proteins, NAIP, cIAP1 and cIAP2 expression during macrophage differentiation and M1/M2 polarization.	BIRC2 BIRC3	9.99e-06	3	64	2	29518103
Pubmed	The ubiquitin-associated domain of cellular inhibitor of apoptosis proteins facilitates ubiquitylation.	BIRC2 BIRC3	9.99e-06	3	64	2	25065467
Pubmed	Dual inhibition of classical protein kinase C-α and protein kinase C-β isoforms protects against experimental murine diabetic nephropathy.	PRKCA PRKCB	9.99e-06	3	64	2	23434935
Pubmed	Differential regulation of glycogen synthase kinase-3 beta by protein kinase C isotypes.	PRKCA PRKCB	9.99e-06	3	64	2	1324914
Pubmed	Smac mimetics activate the E3 ligase activity of cIAP1 protein by promoting RING domain dimerization.	BIRC2 BIRC3	9.99e-06	3	64	2	21393245
Pubmed	Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis.	CLTCL1 CLTC	9.99e-06	3	64	2	19509056
Pubmed	Assignment of human inhibitor of apoptosis protein (IAP) genes xiap, hiap-1, and hiap-2 to chromosomes Xq25 and 11q22-q23 by fluorescence in situ hybridization.	BIRC2 BIRC3	9.99e-06	3	64	2	8938457
Pubmed	Recombinant human cytoplasmic dynein heavy chain 1 and 2: observation of dynein-2 motor activity in vitro.	DYNC2H1 DYNC1H1	9.99e-06	3	64	2	21723285
Pubmed	Loss of cIAP1 attenuates soleus muscle pathology and improves diaphragm function in mdx mice.	BIRC2 BIRC3	9.99e-06	3	64	2	23184147
Pubmed	A new PKCα/β/TBX3/E-cadherin pathway is involved in PLCε-regulated invasion and migration in human bladder cancer cells.	PRKCA PRKCB	9.99e-06	3	64	2	24316392
Pubmed	PI3K-independent mTOR activation promotes lapatinib resistance and IAP expression that can be effectively reversed by mTOR and Hsp90 inhibition.	BIRC3 BIRC5	9.99e-06	3	64	2	25692408
Pubmed	Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.	BIRC2 BIRC3	9.99e-06	3	64	2	19464198
Pubmed	Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals.	PRKCA PRKCB	9.99e-06	3	64	2	9814702
Pubmed	Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity.	BIRC2 BIRC3	9.99e-06	3	64	2	21447281
Pubmed	Glomerular clusterin is associated with PKC-alpha/beta regulation and good outcome of membranous glomerulonephritis in humans.	PRKCA PRKCB	9.99e-06	3	64	2	16775601
Pubmed	Increased steady-state levels of CUGBP1 in myotonic dystrophy 1 are due to PKC-mediated hyperphosphorylation.	PRKCA PRKCB	9.99e-06	3	64	2	17936705
Pubmed	Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG.	CLTCL1 CLTC	9.99e-06	3	64	2	22891263
Pubmed	PERK-dependent regulation of IAP translation during ER stress.	BIRC2 BIRC3	9.99e-06	3	64	2	19029953
Pubmed	Cytoplasmic dynein promotes HIV-1 uncoating.	DYNC2H1 DYNC1H1	9.99e-06	3	64	2	25375884
Pubmed	Specific protein kinase C isoforms α and βI are involved in follicle-stimulating hormone-induced mouse follicle-enclosed oocytes meiotic resumption.	PRKCA PRKCB	9.99e-06	3	64	2	23028752
Pubmed	Protein and molecular characterization of hippocampal protein kinase C in C57BL/6 and DBA/2 mice.	PRKCA PRKCB	9.99e-06	3	64	2	7760054
Pubmed	Gas1 is induced during and participates in excitotoxic neuronal death.	BIRC2 BIRC3	9.99e-06	3	64	2	11906213
Pubmed	Protein kinase C regulates rod photoreceptor differentiation through modulation of STAT3 signaling.	PRKCA PRKCB	9.99e-06	3	64	2	20237998
Pubmed	S-Phase-specific activation of PKC alpha induces senescence in non-small cell lung cancer cells.	PRKCA PRKCB	9.99e-06	3	64	2	18162471
Pubmed	Inhibitor of apoptosis proteins as novel targets in inflammatory processes.	BIRC2 BIRC3	9.99e-06	3	64	2	21817100
Pubmed	MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression.	BIRC2 BIRC3	9.99e-06	3	64	2	19276372
Pubmed	The turn motif is a phosphorylation switch that regulates the binding of Hsp70 to protein kinase C.	PRKCA PRKCB	9.99e-06	3	64	2	12080070
Pubmed	Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells.	BIRC2 BIRC3	9.99e-06	3	64	2	14960576
Pubmed	Expression of the inhibitors of apoptosis proteins in cisplatin-resistant prostate cancer cells.	BIRC3 BIRC5	9.99e-06	3	64	2	16142363
Pubmed	Role of protein kinase C in selective inhibition of mouse retinal neurites during contacts with chondroitin sulfates.	PRKCA PRKCB	9.99e-06	3	64	2	18313852
Pubmed	Desmosomal adhesiveness is developmentally regulated in the mouse embryo and modulated during trophectoderm migration.	PRKCA PRKCB	9.99e-06	3	64	2	22819675
Pubmed	Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways.	PRKCA PRKCB	9.99e-06	3	64	2	3755548
Pubmed	Phorbol diester-induced alterations in the expression of protein kinase C isozymes and their mRNAs. Analysis in wild-type and phorbol diester-resistant HL-60 cell clones.	PRKCA PRKCB	9.99e-06	3	64	2	1714454
Pubmed	Genetic variants of the peroxisome proliferator-activated receptor (PPAR) signaling pathway genes and risk of pancreatic cancer.	PRKCA PRKCB	9.99e-06	3	64	2	32367578
Cytoband	11q22	BIRC2 BIRC3	1.04e-04	11	64	2	11q22
Cytoband	Ensembl 112 genes in cytogenetic band chr11q22	DYNC2H1 BIRC2 BIRC3	4.62e-04	107	64	3	chr11q22
Cytoband	17q21.32	SP2 SP6	2.16e-03	49	64	2	17q21.32
Cytoband	Ensembl 112 genes in cytogenetic band chr8q23	RSPO2 PKHD1L1	2.33e-03	51	64	2	chr8q23
Cytoband	14q32	JAG2 DYNC1H1	3.01e-03	58	64	2	14q32
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF10 SP2 ZNF134 ZNF141 ZSCAN12 ZNF337 ZNF875 ZNF316 SP6 ZNF619 ZNF232 ZNF319 ZNF850 SP7 ZNF445	9.50e-10	718	52	15	28
GeneFamily	Ring finger proteins\|Baculoviral IAP repeat containing\|Caspase recruitment domain containing	BIRC2 BIRC3 BIRC5	1.24e-06	8	52	3	419
GeneFamily	Zinc fingers C2H2-type\|Sp transcription factors	SP2 SP6 SP7	1.86e-06	9	52	3	755
GeneFamily	C2 domain containing protein kinases	PRKCA PRKCB	3.60e-04	10	52	2	835
GeneFamily	Dyneins, cytoplasmic	DYNC2H1 DYNC1H1	6.20e-04	13	52	2	538
GeneFamily	Dyneins, axonemal	DNAH10 DNAH7	1.07e-03	17	52	2	536
GeneFamily	WD repeat domain containing\|Caspase recruitment domain containing\|Apoptosome	BIRC2 BIRC3	3.35e-03	30	52	2	959
Coexpression	GSE12198_CTRL_VS_HIGH_IL2_STIM_NK_CELL_UP	JAG2 PCSK5 SP6 BIRC3 ZFYVE26 AXIN1 CSTPP1 NPNT	2.60e-08	199	63	8	M7067
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	JAG2 NRXN2 PRKCB BCAN RYR2 NPNT	4.33e-07	200	64	6	61d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	JAG2 NRXN2 PRKCB BCAN RYR2 NPNT	4.33e-07	200	64	6	5c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	FRAS1 RSPO2 BCAN RYR2 NPNT	5.63e-06	177	64	5	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	FRAS1 RSPO2 BCAN RYR2 NPNT	5.63e-06	177	64	5	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK5 FRAS1 NRXN2 PRKCA BCAN	6.44e-06	182	64	5	ecb5624c9074cc6449fad961df54c926c2681d54
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 DYNC2H1 RSPO2 PRKCB NPNT	7.74e-06	189	64	5	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH10 DYNC2H1 DEFB124 DNAH7 PLXNA2	8.56e-06	193	64	5	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 RSPO2 PRKCB RYR2 NPNT	8.78e-06	194	64	5	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 CXCL17 BIRC5 STK31 NPNT	8.78e-06	194	64	5	d790cfff3664e46fe2fd2f6b0c26896799927845
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DYNC2H1 CLTC PRKCA PRKCB DYNC1H1	9.00e-06	195	64	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DYNC2H1 CLTC PRKCA PRKCB DYNC1H1	9.00e-06	195	64	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Basal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	JAG2 MET FRAS1 CXCL17 LINC02902	9.93e-06	199	64	5	e9c47f565a0a7737ecff68569d668aeb707ae5a6
ToppCell	Biopsy_IPF-Epithelial-Differentiating_Ciliated\|Biopsy_IPF / Sample group, Lineage and Cell type	IFT22 DNAH10 DYNC2H1 CXCL17 DNAH7	1.02e-05	200	64	5	8dfce65e417d6dcacb871d93d1539cdf807002fe
ToppCell	Biopsy_IPF-Epithelial\|Biopsy_IPF / Sample group, Lineage and Cell type	IFT22 DNAH10 DYNC2H1 CXCL17 DNAH7	1.02e-05	200	64	5	76f1ac00b34d07057d8da03d276438b719b46b1d
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Tmem163_Dmrtb1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MET DNAH10 VILL WNT7B	4.41e-05	136	64	4	0376c2907b869c7d42f57af7f65ffdd6246c4d27
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Tnc\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MET DNAH10 VILL WNT7B	7.15e-05	154	64	4	0066b2b8cfc74603e97f271ef5efc7ec512110dc
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Lypd1_Gpr88\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MET FRAS1 DNAH10 WNT7B	7.70e-05	157	64	4	5aee90ad7aaa65fdabc23597451da5e48db8f4e6
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 DNAH10 PKHD1L1 RYR2	8.29e-05	160	64	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 DNAH10 PKHD1L1 RYR2	8.29e-05	160	64	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	RASGRP1 FRAS1 VILL PRKCB	8.49e-05	161	64	4	ebcd5066e82b7760b9da6adc02d11258d1309dab
ToppCell	wk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MET FRAS1 CXCL17 NPNT	9.34e-05	165	64	4	f6887c64af0f26e33316bc5587487e24d76ece2a
ToppCell	Control-T_cells-Tregs\|Control / group, cell type (main and fine annotations)	RASGRP1 BIRC3 PRKCB MRGPRX2	1.02e-04	169	64	4	e1e0983f31ec81b3fad5f9c6140d17f03f81a5dc
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH10 DYNC2H1 DEFB124 DNAH7	1.02e-04	169	64	4	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 DNAH10 PKHD1L1 RYR2	1.02e-04	169	64	4	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	Adult-Epithelial-basal_cell-D231\|Adult / Lineage, Cell type, age group and donor	JAG2 MET FRAS1 PLXNA2	1.15e-04	174	64	4	a4f98afe7d1cc2617f6f7bc8092c41df57474b30
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 FRAS1 ACOT11 PRKCA	1.15e-04	174	64	4	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	JAG2 CXCL17 PLXNA2 NPNT	1.15e-04	174	64	4	3d4c05ea5719ca65e85d1f15198453034791087c
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MET DNAH10 CXCL17 PKHD1L1	1.17e-04	175	64	4	f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	NRXN2 DEFB124 BCAN RYR2	1.22e-04	177	64	4	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FRAS1 NRXN2 PRKCA BCAN	1.22e-04	177	64	4	d05497d2c80a66ec6a4e1733fea3a5534877a6a7
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	NRXN2 DEFB124 BCAN RYR2	1.22e-04	177	64	4	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 RASGRP1 RSPO2 BIRC3	1.22e-04	177	64	4	bde307e67ad8e48a5ff4c0827015f4688f6b3e46
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 FRAS1 ACOT11 PRKCB	1.25e-04	178	64	4	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 RASGRP1 RSPO2 BIRC3	1.31e-04	180	64	4	b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZNF141 ANKRD37 BIRC3 PRKCB	1.33e-04	181	64	4	d66838fca0429cad2079cd8d92a5cd33eb0d3522
ToppCell	Control-Epithelial-Basal\|World / Disease state, Lineage and Cell class	JAG2 MET CXCL17 WNT7B	1.36e-04	182	64	4	759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 RASGRP1 FRAS1 CLTCL1	1.36e-04	182	64	4	1647367b75b4b107af06bb934394168230cfd7c2
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	JAG2 ANKRD37 HELZ2 RYR2	1.36e-04	182	64	4	fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBXO6 VILL CXCL17 WNT7B	1.39e-04	183	64	4	7eaa6ef7c6cf848fd6489f97677f4406318da22f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 DNAH10 PKHD1L1 RYR2	1.42e-04	184	64	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 DNAH10 PKHD1L1 RYR2	1.42e-04	184	64	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 DNAH10 PKHD1L1 RYR2	1.42e-04	184	64	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Lung-nan-21m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MET CXCL17 WNT7B BCAN	1.45e-04	185	64	4	6938ac3cab536cf8a474eba441ce6dcdfcc43b53
ToppCell	droplet-Lung-nan-21m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MET CXCL17 WNT7B BCAN	1.45e-04	185	64	4	0e7351cd6d6e6e8c29573042e168da50ee496cfc
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	JAG2 PCSK5 ACOT11 ANKRD37	1.45e-04	185	64	4	b57dae20c21f984edd2acee4344d86f033108ebf
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	JAG2 PCSK5 ACOT11 ANKRD37	1.45e-04	185	64	4	d3b054d203e575c1bb5455aa7a2e551a0957a760
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	PCSK5 FRAS1 PRKCA NPNT	1.48e-04	186	64	4	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	PCSK5 FRAS1 PRKCA NPNT	1.48e-04	186	64	4	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	COPD-Epithelial-Club\|World / Disease state, Lineage and Cell class	MET CXCL17 WNT7B NPNT	1.48e-04	186	64	4	3006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CXCL17 PRKCA PLXNA2 NPNT	1.48e-04	186	64	4	e83718fabb057100835d3357df407f283d23fe16
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	JAG2 PCSK5 MET PLXNA2	1.51e-04	187	64	4	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	FRAS1 RSPO2 PRKCB NPNT	1.61e-04	190	64	4	71e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCell	COPD-Epithelial-Club\|COPD / Disease state, Lineage and Cell class	MET CXCL17 WNT7B NPNT	1.64e-04	191	64	4	c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IFT22 DNAH10 DNAH7 CLEC2A	1.64e-04	191	64	4	683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MET FRAS1 DNAH7 NPNT	1.64e-04	191	64	4	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	IPF-Epithelial-Club\|World / Disease state, Lineage and Cell class	MET CXCL17 WNT7B NPNT	1.64e-04	191	64	4	3c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FRAS1 RSPO2 RYR2 NPNT	1.64e-04	191	64	4	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	multiciliated\|World / shred by cell class for turbinate	DNAH10 DYNC2H1 ANKRD37 DNAH7	1.67e-04	192	64	4	0f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	FRAS1 PLXNA2 RYR2 NPNT	1.67e-04	192	64	4	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	MET FRAS1 CXCL17 NPNT	1.71e-04	193	64	4	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	RSPO2 PLXNA2 RYR2 NPNT	1.71e-04	193	64	4	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	background-Cholangiocytes\|background / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 WNT7B BIRC3 NPNT	1.71e-04	193	64	4	9152241073dbe02ac2c11d86bec9b5b529196f6e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	RASGRP1 BIRC3 PRKCB NGLY1	1.74e-04	194	64	4	5cd72330c9d9bb21b6c9d5d35085eade101486d1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MET FRAS1 ACOT11 DNAH7	1.74e-04	194	64	4	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MET CXCL17 DNAH7 NPNT	1.74e-04	194	64	4	6b286992d4bb56013c0ea5a7601d3476d806175a
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MET FRAS1 DNAH7 NPNT	1.74e-04	194	64	4	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH10 DYNC2H1 CXCL17 DNAH7	1.77e-04	195	64	4	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOT11 CLTC PRKCA PRKCB	1.77e-04	195	64	4	bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ACOT11 DNAH7 CSTPP1	1.77e-04	195	64	4	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH10 DYNC2H1 CXCL17 DNAH7	1.77e-04	195	64	4	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FRAS1 RSPO2 PRKCB NPNT	1.81e-04	196	64	4	6730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell	(6)_Endothelial_cells-(6)_Endothelial-B_(Artery)\|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	JAG2 PCSK5 ANKRD37 PLXNA2	1.81e-04	196	64	4	f540cf17b4405a6dd38d2b6123e6541d0aac889e
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MET VILL CXCL17 WNT7B	1.81e-04	196	64	4	b07db4a53ab9be9aad6fae5e45f9547db829d096
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	MET CXCL17 BIRC5 DNAH7	1.81e-04	196	64	4	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FRAS1 RSPO2 PRKCB NPNT	1.81e-04	196	64	4	21dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	MET CXCL17 BIRC5 DNAH7	1.81e-04	196	64	4	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MET VILL CXCL17 WNT7B	1.81e-04	196	64	4	c366f980cc04abfe1c0c14746c11810c812a42c0
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK5 FRAS1 PRKCA BCAN	1.84e-04	197	64	4	bb35a2b7320fda92e9cd42f536b7bd54e3a73a32
ToppCell	B_cells-Naive_B_cells_\|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ZNF10 ANKRD37 BIRC3 PRKCB	1.84e-04	197	64	4	fd5fdc5289d681d59ff22d72e4de6e74c6c7aac6
ToppCell	Severe_COVID-19-Epithelial-transitional_Epi\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	MET DYNC2H1 CXCL17 WNT7B	1.84e-04	197	64	4	5ad3cd4c77016e862041baac3076f8cc0f75c417
ToppCell	COVID-19-Epithelial\|COVID-19 / Condition, Lineage and Cell class	MET DNAH10 CXCL17 DNAH7	1.84e-04	197	64	4	18fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCell	Control_saline-Epithelial_airway\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH10 VILL WNT7B DNAH7	1.88e-04	198	64	4	e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell	normal_Lung-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	FRAS1 RSPO2 PLXNA2 NPNT	1.88e-04	198	64	4	e0e47cf65774191981840b22905b2094b95abe0f
ToppCell	Control_saline-Epithelial_airway-airway_epithelial\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH10 VILL WNT7B DNAH7	1.88e-04	198	64	4	e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell	Biopsy_Control_(H.)-Epithelial-SCGB3A2+\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	MET FRAS1 CXCL17 NPNT	1.88e-04	198	64	4	1fe51f4beca0eef4ff117e6edaa646e35c0f9629
ToppCell	distal-1-Epithelial-Club\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MET CXCL17 WNT7B NPNT	1.92e-04	199	64	4	8f0a72a95d0310ef2324c6975495c294b5a47cc8
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	JAG2 PCSK5 MET FRAS1	1.92e-04	199	64	4	94a7867e800df352731796de8c24cba133c29622
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DNAH10 VILL WNT7B DNAH7	1.92e-04	199	64	4	60919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCell	LPS_anti-TNF-Epithelial_airway\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DNAH10 VILL WNT7B DNAH7	1.92e-04	199	64	4	6aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IFT22 DNAH10 DYNC2H1 DNAH7	1.95e-04	200	64	4	79e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 RSPO2 RYR2 NPNT	1.95e-04	200	64	4	8c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Macroglial-Astrocyte\|10w / Sample Type, Dataset, Time_group, and Cell type.	WNT7B RSPO2 BCAN RPE65	1.95e-04	200	64	4	75f5ea38fbd341b80a8058077a04447f0e0eea28
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	FRAS1 RSPO2 RYR2 NPNT	1.95e-04	200	64	4	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DNAH10 VILL WNT7B DNAH7	1.95e-04	200	64	4	da12821e8a0657869ca0f75d351cce2d7605a505
ToppCell	Biopsy_IPF-Epithelial-Ciliated\|Biopsy_IPF / Sample group, Lineage and Cell type	IFT22 DNAH10 DYNC2H1 DNAH7	1.95e-04	200	64	4	bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	FRAS1 RSPO2 RYR2 NPNT	1.95e-04	200	64	4	a510deaada669e690329183e18df02870bd204b3
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	DNAH10 ZNF337 TNFAIP1 DNAH7	1.95e-04	200	64	4	6b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	NRXN2 PRKCA BCAN LONRF3	1.95e-04	200	64	4	f692b602bc989d35c9162e73dda813dbef8d5267
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	DNAH10 ZNF337 TNFAIP1 DNAH7	1.95e-04	200	64	4	be83f442179ba4217d12f0458059586ff3130991
ToppCell	LPS_IL1RA_TNF-Epithelial_airway\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DNAH10 VILL WNT7B DNAH7	1.95e-04	200	64	4	72c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
Computational	Anti-apoptosis.	BIRC2 BIRC3 BIRC5	2.08e-05	17	35	3	MODULE_537
Computational	Viral anti-apoptotic evasion mechanisms.	BIRC2 BIRC3 BIRC5	4.65e-04	47	35	3	MODULE_312
Drug	NSC339555	RASGRP1 BIRC2 PRKCA BIRC3 PRKCB TNFAIP1	2.01e-06	133	64	6	CID000433902
Drug	evodiamine	BIRC2 PRKCA BIRC3 BIRC5	2.47e-06	34	64	4	ctd:C049639
Drug	AC1NR9P8	CLTCL1 CLTC BIRC2 BIRC3	3.90e-06	38	64	4	CID005287445
Drug	bryostatin 1	PRKCA BIRC3 PRKCB	4.58e-06	12	64	3	ctd:C046785
Drug	S)-HDAC42	BIRC2 BIRC3 BIRC5	5.94e-06	13	64	3	CID006918801
Drug	Badg	CLTCL1 CLTC	7.78e-06	2	64	2	CID000125951
Drug	12-hydroxydaphnetoxin	PRKCA PRKCB	7.78e-06	2	64	2	CID000099841
Drug	dehydroxymethylepoxyquinomicin	BIRC2 BIRC3 BIRC5	9.41e-06	15	64	3	ctd:C464444
Drug	NSC226080	PCSK5 MET ZNF141 CLTCL1 CLTC BIRC2 PRKCA PRKCB TNFAIP1 TOP3A RYR2	1.03e-05	782	64	11	CID000005040
Drug	4-methylene-2-octyl-5-oxofuran-3-carboxylic acid	MET BIRC2 BIRC3	1.40e-05	17	64	3	ctd:C406734
Drug	deca-2,4-dienal	BIRC2 BIRC3 TNFAIP1	1.99e-05	19	64	3	CID000016899
Drug	beta-Jonone	CLTCL1 CLTC PRPH2 RPE65	2.30e-05	59	64	4	CID000026955
Drug	octahydromezerein	PRKCA PRKCB	2.33e-05	3	64	2	CID000164152
Drug	Akt-I-1 compound	BIRC2 BIRC3	2.33e-05	3	64	2	ctd:C501520
Drug	aclacinomycins	BIRC2 BIRC3	2.33e-05	3	64	2	ctd:C011157
Drug	Miniglucagon	CLTCL1 CLTC NGLY1	2.33e-05	20	64	3	CID003080901
Drug	cepharanthine	BIRC2 PRKCA PRKCB TNFAIP1	4.53e-05	70	64	4	CID000010206
Drug	AC1OAR8J	CLTCL1 CLTC	4.65e-05	4	64	2	CID006834124
Drug	daphnetoxin	PRKCA PRKCB	4.65e-05	4	64	2	CID000119454
Drug	gamma-secretase inhibitor I	BIRC2 BIRC3	4.65e-05	4	64	2	CID011754711
Drug	Gg-O	CLTC PRKCB DYNC1H1	4.66e-05	25	64	3	CID016040279
Drug	danthron	BIRC2 BIRC3 BIRC5	4.66e-05	25	64	3	ctd:C004315
Drug	NSC750927	BIRC2 PRKCA BIRC3 PRKCB DYNC1H1 TOP3A	4.80e-05	232	64	6	CID000003461
Drug	diphenyleneiodonium	MET PRKCA PRKCB TNFAIP1 DYNC1H1 RYR2	4.80e-05	232	64	6	CID000003101
Drug	AC1LAIW3	MET PRKCA PRKCB TOP3A	5.06e-05	72	64	4	CID000469261
Drug	lonafarnib	BIRC2 BIRC3 BIRC5	5.26e-05	26	64	3	ctd:C115354
Drug	leptomycin B	BIRC2 PRKCA BIRC3 BIRC5	5.64e-05	74	64	4	ctd:C038753
Drug	diallyl trisulfide	BIRC2 BIRC3 BIRC5 TNFAIP1	5.94e-05	75	64	4	CID000016315
Drug	embelin	BIRC2 BIRC3 TNFAIP1	6.60e-05	28	64	3	CID000003218
Drug	erlotinib	MET CLTC BIRC2 BIRC3 DYNC1H1	7.11e-05	153	64	5	CID000176870
Drug	AVPW	BIRC2 BIRC3	7.74e-05	5	64	2	CID009549245
Drug	12-deoxyphorbolphenylacetate-20-acetate	PRKCA PRKCB	7.74e-05	5	64	2	ctd:C029705
Drug	wartmannin	PCSK5 MET CLTCL1 CLTC BIRC2 PRKCA BIRC3 PRKCB BIRC5 TNFAIP1	8.25e-05	811	64	10	CID000005691
Drug	1'-acetoxychavicol acetate	BIRC2 BIRC3 BIRC5	9.00e-05	31	64	3	ctd:C047948
Drug	NSC-725021	BIRC2 BIRC3	1.16e-04	6	64	2	CID000406741
Drug	ruboxistaurin	PRKCA PRKCB	1.16e-04	6	64	2	ctd:C099154
Drug	tephrosin	BIRC2 BIRC3	1.16e-04	6	64	2	ctd:C480848
Drug	Dendroaspis natriuretic peptide	BIRC2 BIRC3	1.16e-04	6	64	2	ctd:C075597
Drug	thymeleatoxin	PRKCA PRKCB	1.16e-04	6	64	2	ctd:C080287
Drug	kamebakaurin	BIRC2 BIRC3	1.16e-04	6	64	2	ctd:C047382
Drug	AC1L1IPS	CLTCL1 CLTC	1.16e-04	6	64	2	CID000004682
Drug	dichloromethanediamine	PCSK5 BIRC2 PRKCA BIRC3 PRKCB BIRC5 TNFAIP1 TOP3A	1.29e-04	539	64	8	CID005311048
Drug	anacardic acid	BIRC3 BIRC5 SP7	1.30e-04	35	64	3	ctd:C088115
Drug	isoquinolinium	ACOT11 PRKCA PRKCB TNFAIP1	1.37e-04	93	64	4	CID000008405
Drug	Dynasore hydrate	CLTCL1 CLTC	1.62e-04	7	64	2	CID005396227
Drug	C12-NBD-PC	CLTCL1 CLTC	1.62e-04	7	64	2	CID006439314
Drug	Aklavin hydrochloride	BIRC2 BIRC3	1.62e-04	7	64	2	CID000002074
Drug	taxol	ZNF141 BIRC2 PRKCA BIRC3 PRKCB BIRC5 TNFAIP1 TOP3A	1.68e-04	560	64	8	CID000004666
Drug	E 14	MET BCAN DYNC1H1	1.80e-04	39	64	3	CID000122591
Drug	taurolidine	BIRC2 BIRC3 TNFAIP1	1.80e-04	39	64	3	CID000029566
Drug	2f34	CLTCL1 CLTC BIRC2 BIRC3 NGLY1	1.87e-04	188	64	5	CID006420160
Drug	AC1L1GSB	BIRC2 BIRC3 TNFAIP1	1.94e-04	40	64	3	CID000003819
Drug	1-stearoyl-2-arachidonoyl-sn-glycerol	RASGRP1 PRKCA PRKCB	1.94e-04	40	64	3	CID000001398
Drug	TE 5	PCSK5 WNT7B BIRC2	2.09e-04	41	64	3	CID003083341
Drug	PHA-00851261E [724719-49-7]; Up 200; 1uM; MCF7; HT_HG-U133A	MET VILL PRPH2 PRKCA TNFAIP1	2.11e-04	193	64	5	3857_UP
Drug	Na 7	CLTCL1 CLTC	2.15e-04	8	64	2	CID000446006
Drug	gastrin 17	BIRC2 BIRC3	2.15e-04	8	64	2	ctd:C013550
Drug	1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate	BIRC2 BIRC3	2.15e-04	8	64	2	ctd:C477931
Drug	loperamide	PRKCA PRKCB TOP3A RYR2	2.19e-04	105	64	4	CID000003954
Drug	Amethopterin (R,S) [59-05-2]; Down 200; 8.8uM; PC3; HT_HG-U133A	ZNF134 ZNF141 PRKCA TOP3A RYR2	2.22e-04	195	64	5	6654_DN
Drug	PEP005	PRKCA PRKCB NGLY1	2.25e-04	42	64	3	CID006918670
Drug	Tridihexethyl chloride; Up 200; 11.4uM; HL60; HT_HG-U133A	VILL ZNF337 BIRC3 BCAN AXIN1	2.27e-04	196	64	5	2964_UP
Drug	Lynestrenol [52-76-6]; Down 200; 14uM; HL60; HG-U133A	JAG2 ZNF337 ACOT11 BCAN TOP3A	2.32e-04	197	64	5	2037_DN
Drug	NS-398; Down 200; 10uM; MCF7; HT_HG-U133A	PRKCA ZFYVE26 TNFAIP1 TOP3A AXIN1	2.32e-04	197	64	5	6897_DN
Drug	Prednisone [53-03-2]; Down 200; 11.2uM; PC3; HT_HG-U133A	ZNF10 GTF3C2 ACOT11 PRKCA BCAN	2.32e-04	197	64	5	4577_DN
Drug	Nitrocaramiphen hydrochloride; Up 200; 10.8uM; MCF7; HT_HG-U133A	ZNF10 MET PRKCA TOP3A RYR2	2.32e-04	197	64	5	7464_UP
Drug	Dirithromycin [62013-04-1]; Up 200; 4.8uM; HL60; HG-U133A	FRAS1 CLTCL1 BCAN TNFAIP1 DNAH7	2.38e-04	198	64	5	1712_UP
Drug	Thalidomide [50-35-1]; Up 200; 15.4uM; HL60; HG-U133A	GTF3C2 ZNF337 ACOT11 PRKCA TOP3A	2.38e-04	198	64	5	1411_UP
Drug	Acemetacin [53164-05-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A	MET IFT22 ZFYVE26 TNFAIP1 RYR2	2.38e-04	198	64	5	7442_DN
Drug	Azlocillin sodium salt [37091-65-9]; Down 200; 8.2uM; PC3; HT_HG-U133A	ZNF141 ZSCAN12 TNFAIP1 RYR2 AXIN1	2.43e-04	199	64	5	5788_DN
Drug	Terazosin hydrochloride [63590-64-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A	FRAS1 PRKCB LONRF3 PLXNA2 RYR2	2.43e-04	199	64	5	6092_UP
Drug	Guanabenz acetate [23256-50-0]; Down 200; 13.8uM; HL60; HG-U133A	JAG2 ZNF337 ACOT11 PRKCA AXIN1	2.43e-04	199	64	5	2045_DN
Drug	Saquinavir mesylate [149845-06-7]; Down 200; 5.2uM; HL60; HT_HG-U133A	MET DYNC2H1 PRKCA BCAN TOP3A	2.49e-04	200	64	5	6127_DN
Drug	monodansylcadaverine	CLTCL1 CLTC BIRC2 BIRC5	2.71e-04	111	64	4	CID000004247
Drug	myricitrin	VILL PRKCA PRKCB	2.76e-04	45	64	3	CID005281673
Drug	potassium fluoride	NGLY1 DYNC1H1	2.76e-04	9	64	2	CID000518581
Drug	trichloroacetonitrile	BCAN PLXNA2	2.76e-04	9	64	2	CID000011011
Drug	Antagonist G	CLTCL1 CLTC	2.76e-04	9	64	2	CID000163960
Drug	4P-PDOT	CLTCL1 CLTC	2.76e-04	9	64	2	CID003976006
Drug	thiopental	PRKCA PRKCB TNFAIP1 RYR2	2.81e-04	112	64	4	CID003000715
Drug	Lucifer yellow	CLTCL1 CLTC PRKCA PRKCB	2.91e-04	113	64	4	CID006335488
Drug	AC1L18QD	PRPH2 PRKCA PRKCB BCAN RPE65 SP7	3.02e-04	325	64	6	CID000000213
Drug	Zlllal	CLTCL1 CLTC BIRC2 PRKCA BIRC3 PRKCB BIRC5 TNFAIP1	3.10e-04	613	64	8	CID000107707
Drug	AC1L1KZZ	BIRC2 BIRC3 BIRC5	3.14e-04	47	64	3	CID000005725
Drug	tyrphostin 23	CLTCL1 CLTC PRKCA PRKCB	3.21e-04	116	64	4	CID000002052
Drug	iridal	RASGRP1 PRPH2 RPE65	3.35e-04	48	64	3	CID005318463
Drug	zerumbone	BIRC2 BIRC3 BIRC5	3.35e-04	48	64	3	ctd:C403304
Drug	AC1LCVTP	BIRC2 BIRC3 TNFAIP1 NGLY1	3.43e-04	118	64	4	CID000656983
Drug	cc-637	CLTCL1 CLTC	3.45e-04	10	64	2	CID000002350
Drug	tetramethylrhodamine-5-maleimide	CLTCL1 CLTC	3.45e-04	10	64	2	CID005289288
Drug	Vitamin E	PRKCA PRKCB	3.45e-04	10	64	2	DB00163
Drug	acetylaminophenylarsine oxide	CLTCL1 CLTC	3.45e-04	10	64	2	CID006337999
Drug	sn-glycero-3-phosphoserine	PRKCA PRKCB	3.45e-04	10	64	2	CID000444182
Drug	tetronic acid	BIRC2 BIRC3	3.45e-04	10	64	2	CID000521261
Drug	NSC150531	PRKCA PRKCB RPE65	3.56e-04	49	64	3	CID000004475
Drug	ET-18-OCH3	CLTCL1 CLTC PRKCA PRKCB	3.65e-04	120	64	4	CID000001392
Drug	Trimethyltin ion	PRKCA PRKCB TNFAIP1	3.78e-04	50	64	3	CID000021162
Drug	azelnidipine	PRKCA TNFAIP1 DYNC1H1	4.01e-04	51	64	3	CID000065948
Drug	ajoene	BIRC2 BIRC3	4.21e-04	11	64	2	ctd:C048980
Drug	SM 164	BIRC2 BIRC3	4.21e-04	11	64	2	ctd:C533467
Disease	oral squamous cell carcinoma (is_marker_for)	MET BIRC2 BIRC3 BIRC5 AXIN1	2.22e-07	63	62	5	DOID:0050866 (is_marker_for)
Disease	high grade glioma (biomarker_via_orthology)	MET BIRC5 BCAN	3.95e-06	15	62	3	DOID:3070 (biomarker_via_orthology)
Disease	large cell carcinoma (is_implicated_in)	MET PRKCA	1.30e-05	3	62	2	DOID:4552 (is_implicated_in)
Disease	Adenocarcinoma of large intestine	MET PRKCA PRKCB AXIN1	5.08e-05	96	62	4	C1319315
Disease	VACTERL association (implicated_via_orthology)	PCSK5 DYNC2H1	6.48e-05	6	62	2	DOID:14679 (implicated_via_orthology)
Disease	Glioblastoma Multiforme	JAG2 MET PRKCA PRKCB	8.94e-05	111	62	4	C1621958
Disease	HEPATOCELLULAR CARCINOMA	MET AXIN1	1.55e-04	9	62	2	114550
Disease	Hepatocellular carcinoma	MET AXIN1	1.55e-04	9	62	2	cv:C2239176
Disease	lung non-small cell carcinoma (is_marker_for)	MET BIRC2 BIRC3 AXIN1	4.47e-04	169	62	4	DOID:3908 (is_marker_for)
Disease	hair color	SP2 FRAS1 WNT7B SP6 RSPO2	4.99e-04	311	62	5	EFO_0003924
Disease	exercise test	PRKCA RYR2	8.05e-04	20	62	2	EFO_0004328
Disease	triglyceride measurement, body fat percentage	DNAH10 SP6	8.89e-04	21	62	2	EFO_0004530, EFO_0007800
Disease	body fat percentage, high density lipoprotein cholesterol measurement	DNAH10 SP6	1.26e-03	25	62	2	EFO_0004612, EFO_0007800
Disease	triacylglycerol 50:1 measurement	PCSK5 GTF3C2	1.47e-03	27	62	2	EFO_0010408
Disease	urinary bladder cancer (is_marker_for)	WNT7B PRKCA BIRC5	1.50e-03	107	62	3	DOID:11054 (is_marker_for)
Disease	congestive heart failure (biomarker_via_orthology)	PRKCA PRKCB BIRC5	1.50e-03	107	62	3	DOID:6000 (biomarker_via_orthology)
Disease	abdominal:gluteofemoral adipose tissue ratio measurement	DNAH10 SP6	1.70e-03	29	62	2	EFO_0803320
Disease	Polydactyly	FRAS1 ZNF141 DYNC2H1	1.94e-03	117	62	3	C0152427
Disease	Adult T-Cell Lymphoma/Leukemia	PRKCB BIRC5	1.94e-03	31	62	2	C0023493

Protein segments in the cluster

Peptide	Gene	Start	Entry
QCFFCFKELEGWEPD	BIRC5	56	O15392
DEICCWSFYGQGRKL	TNFAIP1	206	Q13829
WSFYGQGRKLAEVCC	TNFAIP1	211	Q13829
KPTFCDNCAGFLWGV	RASGRP1	551	O95267
GFCLWREGDQLTKCC	ACOT11	531	Q8WXI4
DRVACFACGGKLSNW	BIRC3	201	Q13489
VVKDWFAARADCGCT	FBXO6	166	Q9NRD1
EDLAWSCGFPDCAKF	ANKRD37	101	Q7Z713
CDVGLRFCNPGWDAF	BCAN	681	Q96GW7
FQDGEDWRLSRCAKC	FRAS1	166	Q86XX4
FFHWVNNVLCSKCGG	NGLY1	241	Q96IV0
SCNFDHGLCGWIREK	NPNT	421	Q6UXI9
DGVNWFRCECAPGFA	JAG2	806	Q9Y219
GWFQLGKECLLQCRE	PCSK5	1541	Q92824
KADRKFECGWCSGER	PLXNA2	816	O75051
NGGVCREGWNRFICD	NRXN2	701	Q9P2S2
FIWGFGKQGFQCQVC	PRKCB	56	P05771
RIFVGLVKCGAWGCF	DYNC2H1	1726	Q8NCM8
LVKCGAWGCFDEFNR	DYNC2H1	1731	Q8NCM8
GCEFELWDCGGDAKF	IFT22	56	Q9H7X7
AFWRCFRTVGKNGDL	CSTPP1	81	Q9H6J7
DFWFACTGFRKLEPC	AXIN1	116	O15169
RSEFKRCWKGQGACQ	DEFB124	21	Q8NES8
FFKGLLSCGAWACFD	DNAH7	1366	Q8WXX0
AAFKKCREVFRACWG	LINC02902	56	Q6ZTY9
VGLCQVGAWGCFDEF	DYNC1H1	1946	Q14204
GGQECECKDWFLRAP	CXCL17	46	Q6UXB2
FGACGKLWESFIREC	HELZ2	921	Q9BYK8
QCGAWGCFDEFNRID	DNAH10	1876	Q8IVF4
ERCWEFFPAGDCFRK	RYR2	4946	Q92736
IFWFGACDIGLDACL	OR52M1	86	Q8NGK5
LTICGWDFGFRRNNK	MET	581	P08581
NGFLIVDLCCWKGFE	RPE65	321	Q16518
FIWGFGKQGFQCQVC	PRKCA	56	P17252
DRPFVCNWLFCGKRF	SP6	281	Q3SY56
KFCGFLFSDGDSGWC	MRGPRX2	166	Q96LB1
CSRNNRTCGFKWGLE	RSPO2	156	Q6UXX9
DRVACFACGGKLSNW	BIRC2	216	Q13490
WFLQEEKRECFGACL	CLTC	1556	Q00610
WFLEEGKRECFAACL	CLTCL1	1556	P53675
VACSGDWLGVRDKCF	CLEC2A	56	Q6UVW9
GGLFSEDQCWYRCKV	STK31	86	Q9BXU1
QFRFGRWNCSALGEK	WNT7B	76	P56706
ERPFVCNWLFCGKRF	SP7	321	Q8TDD2
IEFKCCGNNGFRDWF	PRPH2	161	P23942
GERPFVCNWFFCGKR	SP2	551	Q02086
GVCNDRCGGWSAKFV	PKHD1L1	2761	Q86WI1
FKCNGGSCNFFLWAD	TOP3A	836	Q13472
VCYLWFGKGCNGDQR	VILL	546	O15195
CEECGKAFKWSLIFN	ZNF141	201	Q15928
ECKECGKFFSWRSNL	ZNF10	266	P21506
QFKCVWCGERFLDVA	ZNF319	541	Q9P2F9
FKCQWCGKEFIGRHT	ZNF445	896	P59923
WICSDCGKTFGRRAA	ZNF316	691	A6NFI3
SRRDTCFDCGKGIWL	TEX13A	391	Q9BXU3
PFECNECGKAFRWGA	ZNF232	331	Q9UNY5
YGIACDNGCIWDLKF	GTF3C2	461	Q8WUA4
CKDCGRGFTWKSNLF	ZNF875	331	P10072
RFWGVFNCLCAGAFG	TMEM42	36	Q69YG0
KCNECGKAFGRWSAL	ZSCAN12	331	O43309
ECKECGKAFRWNASF	ZNF619	441	Q8N2I2
LFGFFCECLRRGEWE	ZFYVE26	16	Q68DK2
DVLGGWCRDSEFRCK	ZNF850	71	A8MQ14
KLHTCGACGRQFWFS	ZNF134	76	P52741
RWGAFKCAERGQDFS	ZNF337	176	Q9Y3M9
FVCNVCGQGFSWKRS	ZNF337	656	Q9Y3M9
EVWDGFKCRKCHGFL	LONRF3	151	Q496Y0