Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncAMP-dependent protein kinase activity

PRKACA PRKACB PRKACG

1.56e-067723GO:0004691
GeneOntologyMolecularFunctioncyclic nucleotide-dependent protein kinase activity

PRKACA PRKACB PRKACG

3.72e-069723GO:0004690
GeneOntologyMolecularFunctionAMP-activated protein kinase activity

PRKACA PRKACB PRKACG

5.30e-0610723GO:0004679
GeneOntologyMolecularFunctionphosphatidylinositol 3-kinase regulator activity

WASH6P WASH3P FLT3

3.53e-0518723GO:0035014
GeneOntologyMolecularFunctiontelomerase RNA binding

SMG7 GAR1 HNRNPU

9.77e-0525723GO:0070034
GeneOntologyMolecularFunctionpromoter-specific chromatin binding

TRIM33 RBL2 NDN HNRNPU

2.30e-0483724GO:1990841
GeneOntologyMolecularFunctiongamma-tubulin binding

WASH6P WASH3P NDN

3.46e-0438723GO:0043015
GeneOntologyMolecularFunctionphosphatidylinositol 3-kinase inhibitor activity

WASH6P WASH3P

3.54e-048722GO:0141039
GeneOntologyMolecularFunctionphosphatidylinositol-3,4,5-trisphosphate binding

INPPL1 BTK JPH2

7.35e-0449723GO:0005547
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO9A MYO9B DNAI2 KIF17

8.75e-04118724GO:0003774
GeneOntologyMolecularFunctionubiquitin protein ligase binding

WASH6P WASH3P FLT3 PRKACA PRKACB SORBS1

1.35e-03337726GO:0031625
GeneOntologyMolecularFunctionprotein kinase activity

FLT3 TRIO PIK3CB CSNK2A2 BTK PRKACA PRKACB PRKACG

1.40e-03600728GO:0004672
GeneOntologyMolecularFunctionactin binding

WASH6P WASH3P MYO9A MYO9B INPPL1 SORBS1 HNRNPU

1.68e-03479727GO:0003779
GeneOntologyMolecularFunctionsulfuric ester hydrolase activity

SGSH IDS

1.68e-0317722GO:0008484
GeneOntologyMolecularFunctioncytoskeletal protein binding

WASH6P WASH3P MYO9A MYO9B STXBP5L INPPL1 STAU2 NDN SORBS1 KIF17 HNRNPU

1.84e-0310997211GO:0008092
GeneOntologyMolecularFunctionubiquitin-like protein ligase binding

WASH6P WASH3P FLT3 PRKACA PRKACB SORBS1

1.84e-03358726GO:0044389
GeneOntologyMolecularFunctionprotein serine kinase activity

TRIO PIK3CB CSNK2A2 PRKACA PRKACB PRKACG

1.97e-03363726GO:0106310
GeneOntologyMolecularFunctionprotein kinase A regulatory subunit binding

PRKACA PRKACG

3.65e-0325722GO:0034237
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

FLT3 TRIO PIK3CB CSNK2A2 BTK PRKACA PRKACB PRKACG

3.93e-03709728GO:0016773
GeneOntologyBiologicalProcessproteoglycan catabolic process

SGSH BTK IDS

6.60e-0611723GO:0030167
GeneOntologyBiologicalProcesshigh-density lipoprotein particle assembly

PRKACA PRKACB PRKACG

1.14e-0513723GO:0034380
GeneOntologyBiologicalProcessregulation of plasma lipoprotein particle levels

WASH6P WASH3P PRKACA PRKACB PRKACG

3.02e-05103725GO:0097006
GeneOntologyBiologicalProcessdendritic transport

STAU2 KIF17 HNRNPU

3.80e-0519723GO:0098935
GeneOntologyBiologicalProcessnegative regulation of meiotic cell cycle

PRKACA PRKACB HORMAD1

7.83e-0524723GO:0051447
GeneOntologyBiologicalProcessrenal water homeostasis

PRKACA PRKACB PRKACG

1.00e-0426723GO:0003091
GeneOntologyBiologicalProcessnegative regulation of catabolic process

WASH6P WASH3P CSNK2A2 PRKACA SECISBP2 QKI BOLL HNRNPU

1.03e-04418728GO:0009895
GeneOntologyBiologicalProcessplasma lipoprotein particle assembly

PRKACA PRKACB PRKACG

1.40e-0429723GO:0034377
GeneOntologyBiologicalProcessdendritic transport of ribonucleoprotein complex

STAU2 HNRNPU

1.79e-046722GO:0098961
GeneOntologyBiologicalProcessdendritic transport of messenger ribonucleoprotein complex

STAU2 HNRNPU

1.79e-046722GO:0098963
GeneOntologyBiologicalProcesspositive regulation of cholesterol import

WASH6P WASH3P

1.79e-046722GO:1904109
GeneOntologyBiologicalProcessprotein-lipid complex assembly

PRKACA PRKACB PRKACG

2.06e-0433723GO:0065005
GeneOntologyBiologicalProcessnegative regulation of mRNA catabolic process

SECISBP2 QKI BOLL HNRNPU

2.44e-0487724GO:1902373
GeneOntologyBiologicalProcessmulticellular organismal-level water homeostasis

PRKACA PRKACB PRKACG

2.46e-0435723GO:0050891
GeneOntologyBiologicalProcessgerm cell development

WASH6P WASH3P STAU2 PRKACA NDN QKI HORMAD1 PYGO1

2.71e-04482728GO:0007281
GeneOntologyBiologicalProcessglycoprotein catabolic process

SGSH BTK IDS

3.95e-0441723GO:0006516
GeneOntologyBiologicalProcessregulation of cholesterol import

WASH6P WASH3P

4.26e-049722GO:0060620
GeneOntologyBiologicalProcessheparan sulfate proteoglycan catabolic process

SGSH IDS

4.26e-049722GO:0030200
GeneOntologyBiologicalProcessnegative regulation of RNA catabolic process

SECISBP2 QKI BOLL HNRNPU

4.32e-04101724GO:1902369
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

WASH6P WASH3P STAU2 PRKACA NDN QKI HORMAD1 PYGO1

4.91e-04527728GO:0022412
GeneOntologyBiologicalProcesspolar body extrusion after meiotic divisions

WASH6P WASH3P

5.31e-0410722GO:0040038
GeneOntologyCellularComponentcAMP-dependent protein kinase complex

PRKACA PRKACB PRKACG

4.82e-0610733GO:0005952
GeneOntologyCellularComponenttelomerase holoenzyme complex

SMG7 GAR1 HNRNPU

8.89e-0525733GO:0005697
GeneOntologyCellularComponentserine/threonine protein kinase complex

CSNK2A2 PRKACA PRKACB PRKACG MED13

2.23e-04157735GO:1902554
GeneOntologyCellularComponentprotein kinase complex

CSNK2A2 PRKACA PRKACB PRKACG MED13

3.22e-04170735GO:1902911
GeneOntologyCellularComponentdendrite cytoplasm

STAU2 KIF17 HNRNPU

3.41e-0439733GO:0032839
GeneOntologyCellularComponentfilopodium

WASH6P WASH3P MYO9B INPPL1

9.08e-04123734GO:0030175
GeneOntologyCellularComponentciliary base

PRKACA PRKACB PRKACG

9.92e-0456733GO:0097546
GeneOntologyCellularComponenttransferase complex, transferring phosphorus-containing groups

PIK3CB CSNK2A2 PRKACA PRKACB PRKACG MED13

1.12e-03335736GO:0061695
GeneOntologyCellularComponentWASH complex

WASH6P WASH3P

1.23e-0315732GO:0071203
GeneOntologyCellularComponentBLOC-1 complex

WASH6P WASH3P

1.77e-0318732GO:0031083
DomainUbiquitin-rel_dom

MYO9A MYO9B RAPGEF5 PIK3CB USP48

5.54e-04184685IPR029071
DomainKinase-like_dom

FLT3 TRIO PIK3CB CSNK2A2 BTK PRKACA PRKACB PRKACG

7.65e-04542688IPR011009
DomainAGC-kinase_C

PRKACA PRKACB PRKACG

1.11e-0356683IPR000961
DomainAGC_KINASE_CTER

PRKACA PRKACB PRKACG

1.11e-0356683PS51285
DomainS_TK_X

PRKACA PRKACB PRKACG

1.11e-0356683SM00133
DomainPROTEIN_KINASE_ATP

FLT3 TRIO CSNK2A2 BTK PRKACA PRKACB PRKACG

1.38e-03459687PS00107
DomainSulfatase_CS

SGSH IDS

1.52e-0316682IPR024607
DomainSULFATASE_1

SGSH IDS

1.71e-0317682PS00523
DomainSULFATASE_2

SGSH IDS

1.71e-0317682PS00149
DomainSulfatase

SGSH IDS

1.92e-0318682PF00884
DomainSulfatase_N

SGSH IDS

1.92e-0318682IPR000917
DomainProt_kinase_dom

FLT3 TRIO CSNK2A2 BTK PRKACA PRKACB PRKACG

1.97e-03489687IPR000719
DomainPROTEIN_KINASE_DOM

FLT3 TRIO CSNK2A2 BTK PRKACA PRKACB PRKACG

2.07e-03493687PS50011
DomainProtein_kinase_ATP_BS

FLT3 CSNK2A2 BTK PRKACA PRKACB PRKACG

2.55e-03379686IPR017441
DomainCRAL_TRIO

MOSPD2 TRIO

2.62e-0321682PF00650
Domain-

MOSPD2 TRIO

3.15e-03236823.40.525.10
DomainSEC14

MOSPD2 TRIO

3.71e-0325682SM00516
DomainPHD

TRIM33 TCF20 PYGO1

4.19e-0389683SM00249
DomainCRAL_TRIO

MOSPD2 TRIO

4.32e-0327682PS50191
DomainZnf_PHD

TRIM33 TCF20 PYGO1

4.46e-0391683IPR001965
DomainCRAL-TRIO_dom

MOSPD2 TRIO

4.64e-0328682IPR001251
DomainZF_PHD_2

TRIM33 TCF20 PYGO1

5.03e-0395683PS50016
DomainZF_PHD_1

TRIM33 TCF20 PYGO1

5.18e-0396683PS01359
DomainZINC_PROTEASE

ADAMTS9 LMLN ECE2

5.49e-0398683PS00142
DomainRA

MYO9A MYO9B

5.67e-0331682SM00314
DomainAlkaline_phosphatase_core

SGSH IDS

5.67e-0331682IPR017850
DomainAlkaline_Pase-like_a/b/a

SGSH IDS

5.67e-0331682IPR017849
Domain-

SGSH IDS

5.67e-03316823.40.720.10
DomainSH2

INPPL1 BTK SH2D2A

5.96e-03101683PF00017
DomainMAGE

MAGED4 NDN

6.80e-0334682SM01373
DomainSH2

INPPL1 BTK SH2D2A

7.55e-03110683SM00252
DomainMAGE

MAGED4 NDN

7.60e-0336682PS50838
DomainMAGE

MAGED4 NDN

7.60e-0336682PF01454
DomainRA

MYO9A MYO9B

7.60e-0336682PF00788
DomainMHD_dom

MAGED4 NDN

7.60e-0336682IPR002190
DomainSH2

INPPL1 BTK SH2D2A

7.74e-03111683PS50001
DomainSH2

INPPL1 BTK SH2D2A

7.93e-03112683IPR000980
Domain-

INPPL1 BTK SH2D2A

7.93e-031126833.30.505.10
DomainSH3

TRIO BTK SORBS1 RUSC2

7.96e-03216684SM00326
DomainSH3

TRIO BTK SORBS1 RUSC2

7.96e-03216684PS50002
DomainRA

MYO9A MYO9B

8.01e-0337682PS50200
DomainMyosin_head_motor_dom

MYO9A MYO9B

8.44e-0338682IPR001609
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_KEY_METABOLIC_FACTORS

PRKACA PRKACB PRKACG

4.71e-075523M26988
PathwayKEGG_MEDICUS_REFERENCE_PKA_HOLOENZYME

PRKACA PRKACB PRKACG

1.64e-067523M47896
PathwayREACTOME_HDL_ASSEMBLY

PRKACA PRKACB PRKACG

2.62e-068523M27840
PathwayREACTOME_ROBO_RECEPTORS_BIND_AKAP5

PRKACA PRKACB PRKACG

3.92e-069523M27877
PathwayKEGG_MEDICUS_REFERENCE_AVP_V2R_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

5.58e-0610523M47648
PathwayREACTOME_REGULATION_OF_GLYCOLYSIS_BY_FRUCTOSE_2_6_BISPHOSPHATE_METABOLISM

PRKACA PRKACB PRKACG

1.02e-0512523M27950
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_ADENYLATE_CYCLASE

PRKACA PRKACB PRKACG

1.02e-0512523M27363
PathwayWP_DOPAMINE_METABOLISM

PRKACA PRKACB PRKACG

1.32e-0513523M39622
PathwayREACTOME_RET_SIGNALING

PIK3CB PRKACA PRKACB PRKACG

1.36e-0540524M27746
PathwayKEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

2.09e-0515523M47794
PathwayKEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

2.09e-0515523M47504
PathwayKEGG_MEDICUS_REFERENCE_DRD1_GNAS_AC_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

2.56e-0516523M47551
PathwayKEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

2.56e-0516523M47645
PathwayKEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

2.56e-0516523M47650
PathwayREACTOME_RAP1_SIGNALLING

PRKACA PRKACB PRKACG

2.56e-0516523M923
PathwayREACTOME_PKA_ACTIVATION_IN_GLUCAGON_SIGNALLING

PRKACA PRKACB PRKACG

3.10e-0517523M26995
PathwayKEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

3.10e-0517523M47544
PathwayREACTOME_SIGNALING_BY_VEGF

PIK3CB PRKACA PRKACB PRKACG SH2D2A

4.29e-05106525M27077
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY

PRKACA PRKACB PRKACG

4.40e-0519523M27841
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB

PRKACA PRKACB PRKACG

5.16e-0520523M759
PathwayWP_RAS_SIGNALING

FLT3 RAPGEF5 PIK3CB PRKACA PRKACB PRKACG

5.64e-05184526M39764
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

PRKACA PRKACB PRKACG

6.01e-0521523M27485
PathwayREACTOME_TRIGLYCERIDE_CATABOLISM

PRKACA PRKACB PRKACG

9.07e-0524523M10064
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

9.07e-0524523M47520
PathwayREACTOME_DARPP_32_EVENTS

PRKACA PRKACB PRKACG

9.07e-0524523M751
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAI_AC_PKA_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

1.16e-0426523M47553
PathwayPID_IL3_PATHWAY

PRKACA PRKACB PRKACG

1.16e-0426523M182
PathwayKEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

1.30e-0427523M47518
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_RASD1_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

1.30e-0427523M47519
PathwayREACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS

RHOG FLT3 PIK3CB CSNK2A2 PRKACA PRKACB PRKACG

1.41e-04313527M27867
PathwayKEGG_INSULIN_SIGNALING_PATHWAY

PIK3CB PRKACA PRKACB PRKACG SORBS1

1.45e-04137525M18155
PathwayKEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

1.45e-0428523M47647
PathwayWP_LIPID_METABOLISM_PATHWAY

PRKACA PRKACB PRKACG

1.62e-0429523M39762
PathwayKEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

1.62e-0429523M47627
PathwayWP_CANNABINOID_RECEPTOR_SIGNALING

PRKACA PRKACB PRKACG

1.62e-0429523M39676
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

1.62e-0429523M47515
PathwayWP_GPR143_IN_MELANOCYTES_AND_RETINAL_PIGMENT_EPITHELIUM_CELLS

PRKACA PRKACB PRKACG

1.79e-0430523M42578
PathwayKEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

1.98e-0431523M47507
PathwayREACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION

PRKACA PRKACB

1.98e-046522MM14628
PathwayKEGG_MEDICUS_REFERENCE_ACTH_CORTISOL_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

2.18e-0432523M47506
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

MAG TRIO MYO9B PIK3CB UNC5B CSNK2A2 PRKACA PRKACB PRKACG

2.25e-04575529M29853
PathwayWP_CARDIOMYOCYTE_SIGNALING_CONVERGING_ON_TITIN

PRKACA PRKACB PRKACG

2.39e-0433523M48071
PathwayREACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION

PRKACA PRKACB PRKACG

2.39e-0433523M11575
PathwayKEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION

PIK3CB PRKACA PRKACB PRKACG

2.67e-0485524M3578
PathwayREACTOME_HDL_ASSEMBLY

PRKACA PRKACB

2.77e-047522MM15560
PathwayKEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_DEGRADATION

SGSH IDS

2.77e-047522M47608
PathwayKEGG_PRION_DISEASES

PRKACA PRKACB PRKACG

2.85e-0435523M13036
PathwayKEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

2.85e-0435523M47969
PathwayKEGG_APOPTOSIS

PIK3CB PRKACA PRKACB PRKACG

2.92e-0487524M8492
PathwayPID_GMCSF_PATHWAY

PRKACA PRKACB PRKACG

3.10e-0436523M22
PathwayREACTOME_CA_DEPENDENT_EVENTS

PRKACA PRKACB PRKACG

3.37e-0437523M749
PathwayREACTOME_RET_SIGNALING

PIK3CB PRKACA PRKACB

3.65e-0438523MM15493
PathwayREACTOME_TRIGLYCERIDE_METABOLISM

PRKACA PRKACB PRKACG

3.65e-0438523M27856
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

TRIO MYO9B PIK3CB CSNK2A2 PRKACA PRKACB

3.79e-04261526MM15676
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

PRKACA PRKACB PRKACG KIF17

3.93e-0494524M2843
PathwayWP_COMMON_PATHWAYS_UNDERLYING_DRUG_ADDICTION

PRKACA PRKACB PRKACG

4.57e-0441523M39655
PathwayREACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING

PIK3CB INPPL1 PRKACA

4.57e-0441523MM15162
PathwayREACTOME_DAG_AND_IP3_SIGNALING

PRKACA PRKACB PRKACG

4.57e-0441523M512
PathwayWP_HIPPO_SIGNALING_REGULATION

FLT3 PRKACA PRKACB PRKACG

4.60e-0498524M39830
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

PRKACA PRKACB PRKACG

4.91e-0442523M791
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

EOMES HOXA4 MAG TRIM33 TRIO MYO9B PIK3CB UNC5B CSNK2A2 PRKACA PRKACB PRKACG MED13 HNRNPU

5.06e-0414325214M509
PathwayWP_HEDGEHOG_SIGNALING_WP4249

PRKACA PRKACB PRKACG

5.26e-0443523M39706
PathwayREACTOME_ADORA2B_MEDIATED_ANTI_INFLAMMATORY_CYTOKINES_PRODUCTION

PRKACA PRKACB PRKACG

5.26e-0443523M29837
PathwayREACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS

PRKACA PRKACB PRKACG

5.26e-0443523M933
PathwayREACTOME_SIGNALING_BY_VEGF

PIK3CB PRKACA PRKACB SH2D2A

5.56e-04103524MM14752
PathwayWP_VASOPRESSINREGULATED_WATER_REABSORPTION

PRKACA PRKACB PRKACG

5.64e-0444523M42554
PathwayKEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION

PRKACA PRKACB PRKACG

5.64e-0444523M9011
PathwayREACTOME_GPER1_SIGNALING

PRKACA PRKACB PRKACG

6.02e-0445523M45008
PathwayREACTOME_METABOLISM_OF_CARBOHYDRATES

SGSH PRKACA PRKACB PRKACG CHST1 IDS

6.38e-04288526M16864
PathwayBIOCARTA_AKAP95_PATHWAY

PRKACB PRKACG

7.19e-0411522M5731
PathwayBIOCARTA_PLCE_PATHWAY

PRKACB PRKACG

7.19e-0411522M5576
PathwayREACTOME_MUCOPOLYSACCHARIDOSES

SGSH IDS

7.19e-0411522M27160
PathwayBIOCARTA_CFTR_PATHWAY

PRKACB PRKACG

7.19e-0411522M12399
PathwayBIOCARTA_AGPCR_PATHWAY

PRKACB PRKACG

7.19e-0411522M19829
PathwayBIOCARTA_AKAP13_PATHWAY

PRKACB PRKACG

7.19e-0411522M17668
PathwayPID_PI3KCI_PATHWAY

PIK3CB INPPL1 BTK

7.28e-0448523M141
PathwayREACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING

PIK3CB INPPL1 PRKACA

7.28e-0448523M914
PathwayBIOCARTA_CARM1_PATHWAY

PRKACB PRKACG

8.60e-0412522M7968
PathwayKEGG_TASTE_TRANSDUCTION

PRKACA PRKACB PRKACG

9.21e-0452523M5785
PathwayREACTOME_AQUAPORIN_MEDIATED_TRANSPORT

PRKACA PRKACB PRKACG

9.21e-0452523M920
PathwayBIOCARTA_DREAM_PATHWAY

PRKACB PRKACG

1.01e-0313522M18899
PathwayWP_HIPPOMERLIN_SIGNALING_DYSREGULATION

FLT3 PRKACA PRKACB PRKACG

1.02e-03121524M39823
PathwayREACTOME_G_PROTEIN_MEDIATED_EVENTS

PRKACA PRKACB PRKACG

1.03e-0354523M26911
PathwayKEGG_VIBRIO_CHOLERAE_INFECTION

PRKACA PRKACB PRKACG

1.03e-0354523M17906
PathwayKEGG_HEDGEHOG_SIGNALING_PATHWAY

PRKACA PRKACB PRKACG

1.14e-0356523M1053
PathwayBIOCARTA_GATA3_PATHWAY

PRKACB PRKACG

1.18e-0314522M1394
PathwayBIOCARTA_AKAPCENTROSOME_PATHWAY

PRKACB PRKACG

1.18e-0314522M15347
PathwayKEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_PI3K_SIGNALING_PATHWAY

FLT3 PIK3CB

1.18e-0314522M47390
PathwayREACTOME_LEISHMANIA_INFECTION

MYO9B BTK PRKACA PRKACB PRKACG

1.24e-03219525M29836
PathwayREACTOME_RAP1_SIGNALLING

PRKACA PRKACB

1.36e-0315522MM15019
PathwayREACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS

PRKACA PRKACB

1.36e-0315522MM15103
PathwayKEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_PI3K_SIGNALING_PATHWAY

FLT3 PIK3CB

1.36e-0315522M47475
PathwayREACTOME_DEGRADATION_OF_GLI1_BY_THE_PROTEASOME

PRKACA PRKACB PRKACG

1.40e-0360523M27470
PathwayBIOCARTA_CK1_PATHWAY

PRKACB PRKACG

1.55e-0316522M16626
PathwayREACTOME_DARPP_32_EVENTS

PRKACA PRKACB

1.55e-0316522MM14699
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB

PRKACA PRKACB

1.55e-0316522MM14492
PathwayBIOCARTA_SHH_PATHWAY

PRKACB PRKACG

1.55e-0316522M11792
PathwayREACTOME_METABOLISM_OF_LIPIDS

EPHX2 PIK3CB CSNK2A2 INPPL1 PRKACA PRKACB PRKACG ETNPPL MED13

1.63e-03757529M27451
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY

PRKACA PRKACB

1.75e-0317522MM15561
PathwayREACTOME_GERM_LAYER_FORMATION_AT_GASTRULATION

EOMES TRIM33

1.75e-0317522M45017
Pubmed

Molecular cloning of a tissue-specific protein kinase (C gamma) from human testis--representing a third isoform for the catalytic subunit of cAMP-dependent protein kinase.

PRKACA PRKACB PRKACG

9.25e-0937432342480
Pubmed

Active cAMP-dependent protein kinase incorporated within highly purified HIV-1 particles is required for viral infectivity and interacts with viral capsid protein.

PRKACA PRKACB PRKACG

9.25e-09374312842892
Pubmed

The paradoxical increase in cortisol secretion induced by dexamethasone in primary pigmented nodular adrenocortical disease involves a glucocorticoid receptor-mediated effect of dexamethasone on protein kinase A catalytic subunits.

PRKACA PRKACB PRKACG

9.25e-09374319383776
Pubmed

Protein kinase A-induced phosphorylation of the p65 subunit of nuclear factor-kappaB promotes Schwann cell differentiation into a myelinating phenotype.

PRKACA PRKACB PRKACG

3.69e-08474318385332
Pubmed

HIV-1 gp120 induces anergy in naive T lymphocytes through CD4-independent protein kinase-A-mediated signaling.

PRKACA PRKACB PRKACG

9.22e-08574312972513
Pubmed

Characterization of the murine orthologue of a novel human subtelomeric multigene family.

WASH6P WASH3P WASH4P

9.22e-08574311701968
Pubmed

Overexpressing PKIB in prostate cancer promotes its aggressiveness by linking between PKA and Akt pathways.

PRKACA PRKACB PRKACG

9.22e-08574319483721
Pubmed

HIV-1 Tat binds to SH3 domains: cellular and viral outcome of Tat/Grb2 interaction.

PRKACA PRKACB PRKACG

9.22e-08574321745501
Pubmed

Effects of [D-Ala1] peptide T-NH2 and HIV envelope glycoprotein gp120 on cyclic AMP dependent protein kinases in normal and psoriatic human fibroblasts.

PRKACA PRKACB PRKACG

9.22e-0857439540970
Pubmed

PKA-mediated stabilization of FoxH1 negatively regulates ERalpha activity.

PRKACA PRKACB PRKACG

9.22e-08574319711044
Pubmed

The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix.

CSNK2A2 PRKACA PRKACB PRKACG

1.34e-07227449151826
Pubmed

Human subtelomeric WASH genes encode a new subclass of the WASP family.

WASH6P WASH3P WASH4P

1.84e-07674318159949
Pubmed

Architectural DNA-binding properties of the spermatidal transition proteins 1 and 2.

PRKACA PRKACB PRKACG

1.84e-0767439837753
Pubmed

Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation.

PRKACA PRKACB PRKACG

1.84e-07674319197368
Pubmed

Dynamic binding of PKA regulatory subunit RI alpha.

PRKACA PRKACB PRKACG

3.22e-07774316407073
Pubmed

Phosphorylation of HIV Nef by cAMP-dependent protein kinase.

PRKACA PRKACB PRKACG

3.22e-07774315629779
Pubmed

CCL3L1 prevents gp120-induced neuron death via the CREB cell signaling pathway.

PRKACA PRKACB PRKACG

5.14e-07874319100722
Pubmed

Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1).

PRKACA PRKACB PRKACG

5.14e-07874312628924
Pubmed

Human immunodeficiency virus proteins induce the inhibitory cAMP/protein kinase A pathway in normal lymphocytes.

PRKACA PRKACB PRKACG

7.70e-0797437688126
Pubmed

HIV-1 Tat-peptide inhibits protein kinase C and protein kinase A through substrate competition.

PRKACA PRKACB PRKACG

1.10e-061074320433920
Pubmed

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts.

PRKACA PRKACB PRKACG

2.01e-061274310830164
Pubmed

Phosphorylation of APOBEC3G by protein kinase A regulates its interaction with HIV-1 Vif.

PRKACA PRKACB PRKACG

2.60e-061374318836454
Pubmed

Viral genetic determinants of nonprogressive HIV type 1 subtype C infection in antiretroviral drug-naive children.

PRKACA PRKACB PRKACG

2.60e-061374319895210
Pubmed

The HIV-1 matrix protein p17 activates the transcription factors c-Myc and CREB in human B cells.

PRKACA PRKACB PRKACG

2.60e-061374320402410
Pubmed

Protein kinase A phosphorylation activates Vpr-induced cell cycle arrest during human immunodeficiency virus type 1 infection.

PRKACA PRKACB PRKACG

2.60e-061374320392842
Pubmed

cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes.

PRKACA PRKACB PRKACG

4.13e-06157432165385
Pubmed

A highly secreted sulphamidase engineered to cross the blood-brain barrier corrects brain lesions of mice with mucopolysaccharidoses type IIIA.

SGSH IDS

4.47e-06274223568409
Pubmed

Endocytic depletion of L-MAG from CNS myelin in quaking mice.

MAG QKI

4.47e-0627428557747
Pubmed

TSAd Plays a Major Role in Myo9b-Mediated Suppression of Malignant Pleural Effusion by Regulating TH1/TH17 Cell Response.

MYO9B SH2D2A

4.47e-06274233046503
Pubmed

Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase.

PRKACA PRKACB

4.47e-0627423023318
Pubmed

Global consequences of activation loop phosphorylation on protein kinase A.

PRKACA PRKACB

4.47e-06274219965870
Pubmed

Necdin interacts with the ribonucleoprotein hnRNP U in the nuclear matrix.

NDN HNRNPU

4.47e-06274211813259
Pubmed

Class IX Myosins: Motorized RhoGAP Signaling Molecules.

MYO9A MYO9B

4.47e-06274232451867
Pubmed

Characterization of the cAMP-dependent protein kinase catalytic subunit Cgamma expressed and purified from sf9 cells.

PRKACA PRKACG

4.47e-06274215039079
Pubmed

Abnormal expression and glycosylation of the large and small isoforms of myelin-associated glycoprotein in dysmyelinating quaking mutants.

MAG QKI

4.47e-0627427545761
Pubmed

Protein kinase A translocation and insulin secretion in pancreatic beta-cells: studies with adenylate cyclase toxin from Bordetella pertussis.

PRKACA PRKACB

4.47e-06274212180908
Pubmed

PKA mediates modality-specific modulation of the mechanically gated ion channel PIEZO2.

PIEZO2 PRKACA

4.47e-06274237146970
Pubmed

Recurrent Rearrangements in PRKACA and PRKACB in Intraductal Oncocytic Papillary Neoplasms of the Pancreas and Bile Duct.

PRKACA PRKACB

4.47e-06274231678302
Pubmed

Mechanism of Bruton's tyrosine kinase-mediated recruitment and regulation of TFII-I.

GTF2I BTK

4.47e-06274214623887
Pubmed

Systems-level identification of PKA-dependent signaling in epithelial cells.

PRKACA PRKACB

4.47e-06274228973931
Pubmed

Investigation of -PRKACA/-PRKACB fusion genes in oncocytic tumors of the pancreatobiliary and other systems.

PRKACA PRKACB

4.47e-06274236152045
Pubmed

PRKACA/PRKACB Fusions in Pancreatobiliary Intraductal Oncocytic Papillary Neoplasms Including Those With Atypical Morphology: An Analysis of 22 Cases Expanding Morphologic Spectrum.

PRKACA PRKACB

4.47e-06274238841868
Pubmed

Regulation of nuclear localization and transcriptional activity of TFII-I by Bruton's tyrosine kinase.

GTF2I BTK

4.47e-06274210373551
Pubmed

Gene Rearrangement and Expression of PRKACA and PRKACB Govern Morphobiology of Pancreatobiliary Oncocytic Neoplasms.

PRKACA PRKACB

4.47e-06274237871652
Pubmed

Molecular and behavioral effects of a null mutation in all PKA C beta isoforms.

PRKACA PRKACB

4.47e-06274212139926
Pubmed

Concomitant targeting of FLT3 and BTK overcomes FLT3 inhibitor resistance in acute myeloid leukemia through the inhibition of autophagy.

FLT3 BTK

4.47e-06274236226489
Pubmed

The C-terminal basic tail of RhoG assists the guanine nucleotide exchange factor trio in binding to phospholipids.

RHOG TRIO

4.47e-06274215199069
Pubmed

Targeting BTK for the treatment of FLT3-ITD mutated acute myeloid leukemia.

FLT3 BTK

4.47e-06274226292723
Pubmed

Characterization of genomic clones coding for the C alpha and C beta subunits of mouse cAMP-dependent protein kinase.

PRKACA PRKACB

4.47e-0627422833513
Pubmed

Quaking I controls a unique cytoplasmic pathway that regulates alternative splicing of myelin-associated glycoprotein.

MAG QKI

4.47e-06274220956316
Pubmed

Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all.

PRKACA PRKACB PRKACG

6.15e-061774324189052
Pubmed

The human immunodeficiency virus coat protein gp120 promotes forward trafficking and surface clustering of NMDA receptors in membrane microdomains.

PRKACA PRKACB PRKACG

1.20e-052174322114277
Pubmed

Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase C- and cAMP-dependent protein kinase pathways.

PRKACA PRKACB PRKACG

1.20e-05217439671211
Pubmed

Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice.

WASH6P WASH3P

1.34e-05374238086439
Pubmed

Developmentally regulated alternative splicing of brain myelin-associated glycoprotein mRNA is lacking in the quaking mouse.

MAG QKI

1.34e-0537422454205
Pubmed

FLT3-ITD and TLR9 use Bruton tyrosine kinase to activate distinct transcriptional programs mediating AML cell survival and proliferation.

FLT3 BTK

1.34e-05374225605370
Pubmed

Involvement of the catalytic subunit of protein kinase A and of HA95 in pre-mRNA splicing.

PRKACA PRKACB

1.34e-05374217594903
Pubmed

WASH Regulates Glucose Homeostasis by Facilitating Glut2 Receptor Recycling in Pancreatic β-Cells.

WASH6P WASH3P

1.34e-05374230425062
Pubmed

A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning.

PRKACA PRKACB

1.34e-0537428548807
Pubmed

Epidermal growth factor receptor levels are reduced in mice with targeted disruption of the protein kinase A catalytic subunit.

PRKACA PRKACB

1.34e-05374218380891
Pubmed

WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.

WASH6P WASH3P

1.34e-05374225225459
Pubmed

HIV-1 tat molecular diversity and induction of TNF-alpha: implications for HIV-induced neurological disease.

PRKACA PRKACB PRKACG

1.59e-05237439730685
Pubmed

The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases.

PRKACA PRKACB PRKACG

1.59e-05237439278385
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

RHOG TRIM33 GAR1 TRIO ADAMTS9 RBL2 TRPS1 SORBS1 IDS QKI MED13 ECE2

1.62e-051285741235914814
Pubmed

Role of phosphorylation in the nuclear biology of HIV-1.

PRKACA PRKACB PRKACG

2.61e-052774321651489
Pubmed

WASH knockout T cells demonstrate defective receptor trafficking, proliferation, and effector function.

WASH6P WASH3P

2.67e-05474223275443
Pubmed

Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation.

WASH6P WASH3P

2.67e-05474232492429
Pubmed

Casein kinase 2- and protein kinase A-regulated adenomatous polyposis coli and beta-catenin cellular localization is dependent on p38 MAPK.

CSNK2A2 PRKACA

2.67e-05474215649893
Pubmed

Defects in the medial entorhinal cortex and dentate gyrus in the mouse model of Sanfilippo syndrome type B.

SGSH IDS

2.67e-05474222096577
Pubmed

Regulation of erythroid Krüppel-like factor (EKLF) transcriptional activity by phosphorylation of a protein kinase casein kinase II site within its interaction domain.

CSNK2A2 PRKACA

2.67e-0547429722526
Pubmed

The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance.

WASH6P WASH3P

2.67e-05474231167970
Pubmed

BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement.

GTF2I BTK

2.67e-0547429012831
Pubmed

Regulation of TFII-I activity by phosphorylation.

GTF2I BTK

2.67e-0547429837922
Pubmed

Properties and phosphorylation sites of baculovirus-expressed nuclear inhibitor of protein phosphatase-1 (NIPP-1).

CSNK2A2 PRKACA

2.67e-0547429407077
Pubmed

Expression of myelin protein genes in quaking mouse brain.

MAG QKI

2.67e-0547423418751
Pubmed

Cloning of a mouse protein kinase A catalytic subunit pseudogene and chromosomal mapping of C subunit isoforms.

PRKACA PRKACB

2.67e-0547427873880
Pubmed

Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production.

WASH6P WASH3P

2.67e-05474232879135
Pubmed

c-Src-dependent transcriptional activation of TFII-I.

GTF2I BTK

2.67e-05474211934902
Pubmed

Glucose-dependent regulation of AMP-activated protein kinase in MIN6 beta cells is not affected by the protein kinase A pathway.

PRKACA PRKACB

2.67e-05474223116618
Pubmed

Trafficking defects in WASH-knockout fibroblasts originate from collapsed endosomal and lysosomal networks.

WASH6P WASH3P

2.67e-05474222718907
Pubmed

BIG1 is a binding partner of myosin IXb and regulates its Rho-GTPase activating protein activity.

MYO9A MYO9B

2.67e-05474215644318
Pubmed

Role of caveolin-1 in the modulation of lipolysis and lipid droplet formation.

PRKACA PRKACB

2.67e-05474215111495
Pubmed

Causes and Clinical Features of Infertile Men With Nonobstructive Azoospermia and Histopathologic Diagnosis of Hypospermatogenesis.

HORMAD1 BOLL

2.67e-05474228342926
Pubmed

Identification of phosphorylation sites for Bruton's tyrosine kinase within the transcriptional regulator BAP/TFII-I.

GTF2I BTK

2.67e-05474211373296
Pubmed

Rap1GAP2 is a new GTPase-activating protein of Rap1 expressed in human platelets.

PRKACA PRKACG

2.67e-05474215632203
Pubmed

A humble hexose monophosphate pathway metabolite regulates short- and long-term control of lipogenesis.

PRKACA PRKACG

2.67e-05474212721358
Pubmed

GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor.

PRKACA PRKACB

2.67e-05474231112131
Pubmed

The c-Cbl-associated protein and c-Cbl are two new partners of the SH2-containing inositol polyphosphate 5-phosphatase SHIP2.

INPPL1 SORBS1

2.67e-05474212504111
Pubmed

Discrete control of TRPV4 channel function in the distal nephron by protein kinases A and C.

PRKACA PRKACB

2.67e-05474223709216
Pubmed

Dendritic cells utilize the evolutionarily conserved WASH and retromer complexes to promote MHCII recycling and helper T cell priming.

WASH6P WASH3P

2.67e-05474224886983
Pubmed

Germline and Mosaic Variants in PRKACA and PRKACB Cause a Multiple Congenital Malformation Syndrome.

PRKACA PRKACB

2.67e-05474233058759
Pubmed

Differential role of PKA catalytic subunits in mediating phenotypes caused by knockout of the Carney complex gene Prkar1a.

PRKACA PRKACB

2.67e-05474221852354
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

PRR12 GTF2I TCF20 TRPS1

3.05e-058374428794006
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

RHOG TRIM33 SMG7 MYO9A MYO9B INPPL1 SECISBP2 SORBS1

3.60e-0558874838580884
Pubmed

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.

TRIM33 SMG7 PIK3CB PCDH11Y TRPS1 SLC35A5

3.89e-0529374631741433
Pubmed

Developmentally acquired PKA localisation in mouse oocytes and embryos.

PRKACA PRKACB

4.45e-05574218367160
Pubmed

Bruton's tyrosine kinase (Btk) enhances transcriptional co-activation activity of BAM11, a Btk-associated molecule of a subunit of SWI/SNF complexes.

GTF2I BTK

4.45e-05574215096481
Pubmed

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.

WASH6P WASH3P

4.45e-05574224344185
Pubmed

Signalling of the BCR is regulated by a lipid rafts-localised transcription factor, Bright.

GTF2I BTK

4.45e-05574219214191
Pubmed

Involvement of protein kinase A in patterning of the mouse somatosensory cortex.

PRKACA PRKACB

4.45e-05574216707791
InteractionPKIG interactions

PRKACA PRKACB PRKACG

9.01e-0612713int:PKIG
InteractionTNP1 interactions

PRKACA PRKACB PRKACG

9.01e-0612713int:TNP1
GeneFamilyMyosins, class IX

MYO9A MYO9B

5.53e-0624321103
GeneFamilyWiskott-Aldrich Syndrome protein family

WASH6P WASH3P WASH4P

6.87e-061643314
GeneFamilySulfatases

SGSH IDS

8.25e-0418432410
GeneFamilySH2 domain containing

INPPL1 BTK SH2D2A

1.78e-03101433741
GeneFamilyWD repeat domain containing

UTP15 NBEAL1 STXBP5L DNAI2

3.41e-03262434362
GeneFamilyMAGE family

MAGED4 NDN

4.07e-03404321136
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

MAG TRIO UNC5B

6.59e-03161433593
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAG PIEZO2 MOSPD2 RAPGEF5 MFSD6 PRKACB QKI

3.26e-081927478dc3016601148243196e925641c9507e9d58c9e0
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAG PIEZO2 RAPGEF5 UNC5B MFSD6 QKI

8.64e-07194746cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES OOSP1 SH2D2A AGBL2 KIF17

7.96e-061647451a9b444d2c6abcc83d4355ec5228b27541df2bd0
ToppCelldroplet-Marrow-BM-1m-Hematologic-hematopoietic_precursor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES FLT3 GTF2I GAR1 SH2D2A

1.25e-05180745ff34195bb7325e61fbf823c103c5e6115d8f1248
ToppCell(3)_Mast_cells|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MAG BTK DNAI2 KIAA1549 TM6SF1

1.39e-05184745dbfad62b925d835632b39a88ab95bd9af9cb7bee
ToppCell(3)_Mast_cell|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MAG BTK DNAI2 KIAA1549 TM6SF1

1.39e-05184745482907d3669597e25c8ff3e9a802a31415a0d654
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 PIEZO2 ADAMTS9 QKI ECE2

1.50e-0518774585f1678338a47d91e296f0620d4887f057eb7e70
ToppCellfacs-Pancreas-Endocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STXBP5L PRKACB NDN IDS HNRNPU

1.66e-05191745b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 PIEZO2 PCDH11Y ECE2 PYGO1

1.70e-05192745dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAG PIEZO2 MOSPD2 RAPGEF5 QKI

1.70e-051927453ce5dbde41aeb73d49f2c7991d34682f0827fa5a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM145 NDN QKI ECE2 PYGO1

1.75e-051937459f9eb241b0b82a6f12de6921c3acf6fed7cf65bb
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)|Neuronal / cells hierarchy compared to all cells using T-Statistic

FLT3 PIEZO2 QKI ECE2 PYGO1

2.07e-05200745107854f4855fc99c9f7e737eb246f0d868e6c5fd
ToppCellNS-control-d_0-4-Myeloid-Monocyte-derived_DC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RHOG MFSD6 PRKACB CYB5R4

5.98e-051277441f9039d2a9e418c41716c3608d4d03574b71904a
ToppCellcontrol-Myeloid-Monocyte-derived_DC|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RHOG MFSD6 PRKACB CYB5R4

6.16e-051287444a1f7b76b64df06531db79e427eda084374ce7b5
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod-3|TCGA-Mesothelium / Sample_Type by Project: Shred V9

FLT3 RBL2 MFSD6 KIAA1549

8.02e-05137744a1e34ebbeda3d5a4f14917282d44fcb4dcbf3133
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

ADAMTS9 JPH2 NDN SORBS1

1.46e-04160744fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCellfacs-Lung-nan-3m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES MAG SH2D2A BOLL

1.50e-04161744ae1cee34361dde9964581cca99a29578c3b3bd99
ToppCellfacs-Lung-nan-3m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES MAG SH2D2A BOLL

1.50e-0416174433de3e8b3238fcfc66dfbf89a913a07d464d6c35
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG7 MYO9B INPPL1 STAU2

1.61e-04164744b77995958c938e10a526118f75d78cee72e0b207
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOG TM6SF1 HORMAD1 IL36G

1.61e-0416474445a6d809d92fd4eee906da3c812282bacffc9f2f
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOG TM6SF1 HORMAD1 IL36G

1.61e-04164744aa4358311fc767c292897e3328309d1bcda392d4
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES HOXA4 SH2D2A SLC35A5

1.64e-04165744eeb58d4db64ad37dc6b441eab22b05c24862e1a9
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES UNC5B SH2D2A TM6SF1

1.64e-041657448741df8066a44c841752a99ad306d26ea68f5344
ToppCellmoderate-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAG PIEZO2 KIAA1549 SORBS1

1.68e-04166744c3835b424c63bf11a4e2c47635dc3787fc4a637a
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_Erythro-Mega|bone_marrow / Manually curated celltypes from each tissue

PIEZO2 OOSP1 ADAMTS9 NDN

1.68e-04166744a853005a5587d42daecdf2e23a93109919021a4f
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3|TCGA-Stomach / Sample_Type by Project: Shred V9

FLT3 BTK TM6SF1 SHISA3

1.72e-04167744d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCellASK440-Epithelial-Transformed_epithelium|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

WASH4P ADAMTS9 SORBS1 KIF17

1.93e-04172744df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-cDC1|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT3 PIK3CB TRPS1 DNAI2

1.97e-04173744d13ae4046a25ee0fb492ddedf44583a879a432e9
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 MYO9B RAPGEF5 KIF17

2.06e-0417574412f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DCAF15 PIEZO2 RAPGEF5 AGBL2

2.10e-041767448eb91dcf55d4e3e28a72d447181bf6d2ad891fc6
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES GTF2I RBL2 SH2D2A

2.15e-04177744b8de0fc92691a6d6759c743195b11edd2d63f265
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG RHOG ETNPPL QKI

2.29e-04180744350ba05cec45a788ab33530cc1346daddb00f884
ToppCellThalamus-Macroglia|Thalamus / BrainAtlas - Mouse McCarroll V32

MAG RHOG INPPL1 QKI

2.34e-041817444f62b63854a4e9fea6e839f0340e78392c66fb0e
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(other)|COVID-19 / group, cell type (main and fine annotations)

ADAMTS9 RAPGEF5 TMEM145 SORBS1

2.34e-0418174426eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCellcritical-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAG PRKACB KIAA1549 SORBS1

2.34e-04181744f0d81ae74d3f32979624a94b2ef93774831a7970
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 UNC5B KIAA1549 CHST1

2.34e-04181744cd81bc307e2bc42c1e9b24d5645ab65fa18c6133
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG RHOG ETNPPL QKI

2.39e-041827440beffe6b9b36cfd196ec98a18f6ded080c162f90
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG RHOG UNC5B QKI

2.44e-04183744038edbc879db7bca795fb2f08e47c42476946161
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

ADAMTS9 NBEAL1 RAPGEF5 SORBS1

2.44e-04183744cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellCerebellum-Macroglia|Cerebellum / BrainAtlas - Mouse McCarroll V32

MAG DNAI2 ETNPPL QKI

2.49e-0418474491b047a01d2cad231308279ca37fa699630f7864
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 PIEZO2 QKI ECE2

2.49e-0418474423515c28e1f42aab29cef9e5b4a7f45bda7f5520
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES STXBP5L TMEM145 NDN

2.49e-041847447d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCelldroplet-Marrow-nan-21m-Hematologic-hematopoietic_precursor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EOMES GTF2I NDN SH2D2A

2.49e-041847447e129862f8d2353387999e633725325c4d8cb42e
ToppCellwk_20-22-Epithelial-PNS-intermediate_Schwann|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADAMTS9 SORBS1 QKI MED13

2.49e-041847444e3ba64692868563a579902aa9c6f88cab5bce26
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDN CHST1 PYGO1 SHISA3

2.54e-04185744872720275789d249c9859de825a923803d458875
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 UNC5B KIAA1549 CHST1

2.60e-041867449d6cb36aa0aae69fe584dad31deafcfdcc9fd1db
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|356C / Donor, Lineage, Cell class and subclass (all cells)

MAG RAPGEF5 UNC5B CHST1

2.60e-04186744f0b78c7ee20279970ea8961bf59acb5262f2dce5
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 PIEZO2 ADAMTS9 QKI

2.60e-0418674496f6603cc75fa1ffc2a2fdb94ec0ec09498e540a
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|356C / Donor, Lineage, Cell class and subclass (all cells)

MAG RAPGEF5 UNC5B CHST1

2.60e-041867442b3c814a7dee8286ea113c63dc3de5daf0257d37
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 RAPGEF5 UNC5B KIF17

2.65e-0418774465d406122dffe18279f14a1ed35ba091730b97be
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 RAPGEF5 UNC5B KIF17

2.65e-041877444c15c0ed41a55271fc793cb76fee97fa64190369
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 RAPGEF5 UNC5B KIF17

2.65e-041877445274f2b302bbf7fed30c480af4f35058d2cf61e0
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

PIEZO2 ADAMTS9 RAPGEF5 UNC5B

2.65e-041877441e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell3'-Adult-LargeIntestine-Hematopoietic-Myeloid-Mast_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAG RHOG BTK IDS

2.70e-041887443fe9d698ff8f540edebf8609e7d42d3f81271edb
ToppCellNS-critical-d_0-4-Lymphoid-CTL|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EOMES RBL2 PRKACB SH2D2A

2.76e-04189744fb7572fb4c7c43886d57a025decad076f32a14c4
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAG BTK KIAA1549 IDS

2.76e-04189744f3cb1a8ddf7a4a95fb1b6e8fe5aa63ef037ca7a6
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 ADAMTS9 QKI ECE2

2.81e-0419074426843ec1d19ac85a50990705353b802745d33e4d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 RAPGEF5 UNC5B TM6SF1

2.81e-04190744876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCellNS-critical-d_0-4-Lymphoid|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EOMES RBL2 PRKACB SH2D2A

2.81e-0419074484f9f5ac29ff0f929a589b76efa61d4c570e76b0
ToppCellhuman_hepatoblastoma-Endothelial_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ADAMTS9 RAPGEF5 UNC5B JPH2

2.81e-041907448d6ef93d69e96cd6921816d152bea3b0710cf147
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 RAPGEF5 UNC5B TM6SF1

2.81e-04190744be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 RAPGEF5 UNC5B TM6SF1

2.81e-0419074409a8855901c3c9332dbaab3e40166485b696d0f1
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MAG PIEZO2 ETNPPL QKI

2.81e-04190744ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MAG PIEZO2 ETNPPL QKI

2.87e-041917442b056cbe2e82e056e1f798974999378460eb1d16
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIEZO2 UNC5B KIAA1549 CHST1

2.87e-0419174440e617d3c93f03ae87baf6c0b2304b617f5fe782
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STXBP5L PRKACB NDN IDS

2.87e-04191744657297cd19d05a7e7bb74fc3a086fbd95f47aae4
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTS9 RAPGEF5 UNC5B PCDH11Y

2.93e-0419274427ff3621e177e7932dd44dd6baa81551ea75a874
ToppCellNS-moderate-d_07-13-Lymphoid-CTL|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EOMES RBL2 PRKACB SH2D2A

2.93e-04192744ab2c3d829f5cbf4eb386babcfdf851222a2a88e8
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS9 RAPGEF5 UNC5B TM6SF1

2.93e-041927445a0615fdc217554ccd611504b16e5d97628e207d
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS9 RAPGEF5 UNC5B CHST1

2.93e-041927441f35efb0765e05f7f9c881849953bef3965be25a
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 ADAMTS9 QKI ECE2

2.93e-0419274467d6230e32d446dcb12047fae2c3f1faa80dd720
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 RAPGEF5 PRKACB HNRNPU

2.93e-041927441ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 QKI ECE2 PYGO1

2.93e-04192744bf1943715085c4124b1675888b0615c9500ec888
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 PIEZO2 PCDH11Y QKI

2.99e-04193744d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCellmoderate-Lymphoid-CTL|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

EOMES RBL2 PRKACB SH2D2A

2.99e-041937443fce0807631811da1cff5ca9db23ff1ad36020e7
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 PCDH11Y ECE2 PYGO1

2.99e-04193744010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 PIEZO2 PCDH11Y PYGO1

2.99e-041937442189da4b727e25e62669d7b9257f06493be21a27
ToppCellNS-moderate-d_16-33-Lymphoid-CTL|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EOMES RBL2 PRKACB SH2D2A

3.05e-041947446b2bb3dd11fd53fa9ab4d66c18b0714f96f99288
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 PIEZO2 PCDH11Y PYGO1

3.05e-0419474483863da11dfbe59b2d0a2c08db40b537c150588c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 PIEZO2 PCDH11Y PYGO1

3.05e-041947441bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 QKI ECE2 PYGO1

3.05e-041947444f758718a1233c25c25d99fc1b7b06f906b8b0a2
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAG BTK KIAA1549 IDS

3.05e-041947449d7f232ef5f27c28f325edfa6614f479013acbba
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(Neuron.Gad1Gad2.Pvalb-Unc5b)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FLT3 UNC5B JPH2

3.09e-0479743cc17a013a4a57a99c404b10449ef61ce559631d1
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(Neuron.Gad1Gad2.Pvalb-Unc5b)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FLT3 UNC5B JPH2

3.09e-047974319fb2bc964589ea40e7b9f0809c641331c93dacd
ToppCellfacs-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 RAPGEF5 UNC5B QKI

3.11e-041957447f9b7f15006610ad591063d90e90367bd6083c7f
ToppCellMS-mDC2|MS / Condition, Cell_class and T cell subcluster

FLT3 BTK TM6SF1 KIF17

3.17e-041967444707e4a911c6ea032f69aa1e431d5f4260bda011
ToppCellMS-mDC2-|MS / Condition, Cell_class and T cell subcluster

FLT3 BTK TM6SF1 KIF17

3.17e-04196744064029b1376fa673f25f80596609be86ce0409a9
ToppCellCOVID-19-Myeloid-Transitioning_MDM|COVID-19 / group, cell type (main and fine annotations)

MYO9B TRPS1 CYB5R4 QKI

3.17e-041967444929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell|GW09 / Sample Type, Dataset, Time_group, and Cell type.

RHOG TRIO LMLN SH2D2A

3.17e-041967447be50b9156394dea44d7b8b476d4dd516abfafae
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG7 QKI MED13 HNRNPU

3.17e-04196744151f1a29a91f8b234e9b6ed062666357a2f69128
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS9 RAPGEF5 UNC5B TM6SF1

3.23e-0419774498e34e8612f111bb667a574de1faaa785d318ca4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EOMES RBL2 PRKACB SH2D2A

3.23e-0419774432b770e403028862f91e4727f4a8fbb6151910e4
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG RHOG UNC5B QKI

3.23e-041977447b12f9d4ad1e84df58e86591a491c84d4f36eac5
ToppCellSevere_COVID-19-T/NK-CD8+_T|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

EOMES RBL2 PRKACB SH2D2A

3.29e-04198744584f0dc6f22bb13956a5f6950698599e382907e9
ToppCellBAL-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EOMES RBL2 PRKACB SH2D2A

3.29e-041987442eb80255bacddbf778b1c9eec09f74b4cdb09b36
ToppCellControl_saline-Endothelial-Endothelial-Activated_Gen_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

ADAMTS9 RAPGEF5 SORBS1 QKI

3.29e-041987443c3a5d2555f6af4aa33f9ea778808315d0e39d86
ToppCellBAL-Severe-Lymphocyte-T/NK-CD8+_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

EOMES RBL2 PRKACB SH2D2A

3.29e-04198744ec99da4e269c4cd982a395cdac0e4487ab14ec39
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG RHOG UNC5B QKI

3.29e-04198744fef9a4c96450078527b94d25e681410e4ea01b13
ToppCellBAL-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

EOMES RBL2 PRKACB SH2D2A

3.29e-0419874406fdf8554148d11c0a946a7fd200edd9fa7e1965
ToppCellBronchus_Control_(B.)-Stromal-TX-Smooth_muscle-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

HOXA4 ADAMTS9 JPH2 SORBS1

3.35e-041997442c5ad62919c64ea0242e0984bb9932d2d975f4e3
DrugEnoxacin [74011-58-8]; Down 200; 12.4uM; PC3; HT_HG-U133A

GTF2I SMG7 RAPGEF5 MFSD6 SORBS1 QKI HNRNPU

2.63e-061967174655_DN
DrugTiaprofenic acid [33005-95-7]; Up 200; 15.4uM; MCF7; HT_HG-U133A

DNAI2 PRKACA PRKACG NDN SORBS1 CHST1 SH2D2A

2.81e-061987174171_UP
Drugrotenone; Up 200; 1uM; PC3; HT_HG-U133A

DCAF15 SMG7 TRIO MYO9B PRKACG IL36G RUSC2

2.91e-061997175920_UP
Drug8-N3cAMP

PRKACA PRKACB PRKACG

1.03e-0514713CID006426627
Drug8-(6-aminohexyl)amino cyclic AMP

PRKACA PRKACB PRKACG

1.03e-0514713CID000161999
DrugGF109203X

RHOG PIK3CB RBL2 INPPL1 BTK PRKACA PRKACB PRKACG

1.09e-05341718CID000002396
DrugNA-382

PRKACA PRKACB PRKACG

1.29e-0515713CID000132534
Drugphosphine oxide

MAG RBL2 PRKACA PRKACB PRKACG

2.12e-05107715CID000166931
Drug8-azido cyclic AMP

PRKACA PRKACB PRKACG

2.29e-0518713CID000115296
Drug8-thiomethyl-cAMP

PRKACA PRKACB PRKACG

2.72e-0519713CID000093140
Drug8-azidoadenosine

PRKACA PRKACB PRKACG

2.72e-0519713CID000160751
Drugtyrphostin 23

RBL2 PRKACA PRKACB PRKACG HNRNPU

3.13e-05116715CID000002052
DrugDiphenidol hydrochloride [3254-89-5]; Down 200; 11.6uM; MCF7; HT_HG-U133A

TRIM33 MOSPD2 PIK3CB IDS QKI HNRNPU

3.20e-051947167406_DN
DrugLY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A

GTF2I TRIO SGSH QKI USP48 HNRNPU

3.30e-051957165213_DN
DrugApomorphine hydrochloride hemihydrate [41372-20-7]; Down 200; 6.4uM; HL60; HG-U133A

DCAF15 SMG7 MYO9A RBL2 UNC5B SLC35A5

3.39e-051967162005_DN
DrugCP-863187 [668981-07-5]; Down 200; 10uM; PC3; HT_HG-U133A

TRIO STAU2 TRPS1 CYB5R4 IDS QKI

3.49e-051977167512_DN
DrugAconitine [302-27-2]; Down 200; 6.2uM; HL60; HG-U133A

MOSPD2 GTF2I SMG7 PRKACA IDS USP48

3.59e-051987161784_DN
DrugEtanidazole [22668-01-5]; Up 200; 18.6uM; MCF7; HT_HG-U133A

RAPGEF5 UNC5B MFSD6 ETNPPL NDN CHST1

3.69e-051997166072_UP
Drugtetraethylenepentamine pentahydrochloride; Up 200; 100uM; MCF7; HG-U133A

DCAF15 GTF2I TRIO PIK3CB RBL2 ECE2

3.69e-05199716406_UP
DrugSp-8-Cl-cAMPS

PRKACA PRKACB PRKACG

4.29e-0522713CID000133987
Drug7B-forskolin

PRKACA PRKACB PRKACG

7.18e-0526713CID000130638
DrugH 85

PRKACA PRKACB PRKACG

7.18e-0526713CID006439306
Druglithium dimer

TCF20 RBL2 BOLL

7.18e-0526713CID000139759
DiseaseIntellectual Disability

PRR12 TCF20 TRIO QKI MED13 HNRNPU

6.76e-04447706C3714756
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

TRIO MED13

7.37e-0417702DOID:0060307 (is_implicated_in)
Diseasealcohol use disorder (implicated_via_orthology)

PIK3CB PRKACA PRKACB PRKACG

1.21e-03195704DOID:1574 (implicated_via_orthology)
DiseaseIntrahepatic Cholangiocarcinoma

PRKACA PRKACB

1.48e-0324702C0345905
DiseaseExtrahepatic Cholangiocarcinoma

PRKACA PRKACB

1.48e-0324702C3805278
DiseaseCholangiocarcinoma

PRKACA PRKACB

1.74e-0326702C0206698
Diseasenecrotizing enterocolitis

TCF20 TRPS1

1.87e-0327702EFO_0003928
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

ADAMTS9 PIK3CB CYB5R4

2.02e-03105703DOID:9352 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
FPEPFVNTLPQARYY

EOMES

476

O95936
ERFPYPFQVVYDEGP

BTK

96

Q06187
APFLYLQPSEVIYQP

BOLL

206

Q8N9W6
LFDYFPKPYPNSEAA

CYC1

171

P08574
PIYALQRNPFYPKNF

DNAI2

366

Q9GZS0
QIIPPAGYFQKVAEY

ETNPPL

221

Q8TBG4
FYEPLQPPQVKALYL

NBEAL1

791

Q6ZS30
LYVPVKEYPDFNFVG

QKI

86

Q96PU8
YPVLQIAEPFQYPQL

KIAA1549

1146

Q9HCM3
YEPIFQDIFKYPQEE

RBL2

166

Q08999
YPPFFADQPIQIYEK

PRKACA

236

P17612
ELAPDFYQPGPEYQK

JPH2

421

Q9BR39
YKKIPNSNPPEYEFL

MAGED4

561

Q96JG8
FNSPYPKNYPPVVFK

MAG

61

P20916
FPKPLPQEYQYFDEL

LMLN

446

Q96KR4
VNAYYLPTKNEIVFP

ECE2

606

P0DPD6
AYLFFPPVVNPIVYS

OR51J1

281

Q9H342
QKEKPYFPIPEEYTF

HNRNPU

461

Q00839
YFPIPEEYTFIQNVP

HNRNPU

466

Q00839
KPPEYRNYQIVFIVF

MFSD6

361

Q6ZSS7
KPTIFYNLYVNPDEV

OOSP1

41

A8MZH6
VNPYPGIPVDANFYK

FLT3

886

P36888
YSFNIPIEDKPQQFY

ADAMTS9

866

Q9P2N4
DLYGQPEPVKPFLFY

IL36G

106

Q9NZH8
KANPVFDYQLYFQEP

EPHX2

376

P34913
YPPFFADQPIQIYEK

PRKACB

236

P22694
FPPFYADQPIQIYEK

PRKACG

236

P22612
LLQVFPKFPYDPSFN

C2orf92

81

A0A1B0GVN3
QPEYFYQPKGNEKVP

AGBL2

201

Q5U5Z8
EHPYFYPVVKEQSQP

CSNK2A2

321

P19784
PFRYPKEFQKLYPLE

IDS

231

P22304
KLFYYDEVTPPDYQP

HORMAD1

176

Q86X24
PYPVFESNPEFLYVE

GTF2I

596

P78347
FLINSNYIEPKFPPF

HOXA4

6

Q00056
NYIEPKFPPFEEYAQ

HOXA4

11

Q00056
KYQVVYPFPTFQPAF

DCAF15

221

Q66K64
NKPVFIVPPYNYSYE

PCDH11Y

701

Q9BZA8
YPPAFQYETVVKPKV

KIF17

486

Q9P2E2
DENKVPYFNAPVYLE

GAR1

91

Q9NY12
PYFNAPVYLENKEQI

GAR1

96

Q9NY12
PFKYSYPPLVDDDFQ

MOSPD2

236

Q8NHP6
PFDDNYNTISYKPLP

PYGO1

71

Q9Y3Y4
QPSEYYLFQKPEVQP

RUSC2

441

Q8N2Y8
HYVELYEKPYPQPVQ

RTL1

446

A6NKG5
VSKVDFSPQPPYNYA

UTP15

41

Q8TED0
EFQEPVPASIPNYYK

TRIM33

981

Q9UPN9
SNPIYNEPDEPIAFY

SH2D2A

276

Q9NP31
NAFPKEYIPTVFDNY

RHOG

26

P84095
PYNHNPSEVKVPEFY

SMG7

856

Q92540
ELPLPTFDVPYFKYI

RAPGEF5

26

Q92565
PPKNSFNNPAYYVLE

INPPL1

976

O15357
LVSPQYFAYPLQQEP

SHISA3

211

A0PJX4
YPFVQEPPVTEQKIY

SECISBP2

51

Q96T21
FPPQYQEAVEPTVYV

MED13

586

Q9UHV7
QPYYYPPFDKIIEKA

PIK3CB

501

P42338
PPFQTPKKLYAQEYE

PRR12

1086

Q9ULL5
EFKEPVLPNNKYIYF

CYB5R4

336

Q7L1T6
TPQAYDPLDVLVPYF

SGSH

211

P51688
TPYPNEFQEPYAVVV

STXBP5L

366

Q9Y2K9
DLYFLENYIKPPPVN

CHST1

131

O43916
PIEKYQYPLFGLPFV

TRPS1

1086

Q9UHF7
LDPKPFPNYRANYNF

STAU2

116

Q9NUL3
FIYNASKPQVPEYAP

SLC35A5

371

Q9BS91
VPENYFYVPDLGQVP

WASH4P

241

A8MWX3
EENPYFPTYKFPELP

SORBS1

411

Q9BX66
LYLYQFQFFQEAVPP

PIEZO2

286

Q9H5I5
VPENYFYVPDLGQVP

WASH3P

226

C4AMC7
FGPFYPQDYAATLPK

TCF20

1721

Q9UGU0
PLPYFLQEPQDAYIV

UNC5B

46

Q8IZJ1
QQYFPKAPEFPSYKE

USP48

676

Q86UV5
PENYFYVPDLGQVPE

WASH6P

211

Q9NQA3
NPNYIYDVPPEFVIP

TRIO

2676

O75962
FPEKQPFYVPFFAAY

TMEM145

341

Q8NBT3
QFQEPYLKDPAAYPK

TM6SF1

251

Q9BZW5
INPFKFLPIYNPKYV

MYO9A

186

B2RTY4
INPFKFLPIYNPKYV

MYO9B

186

Q13459
KYQRVPYVEPPEYEF

NDN

246

Q99608